LOCUS       c00028_gnlPro..        12770 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AOKBEKDI_28.
ACCESSION   c00028_gnlPro..
VERSION     c00028_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:16:58
            Original ID  :: gnl|Prokka|AOKBEKDI_28
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12770
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1731)
                     /locus_tag="ctg28_1"
                     /transl_table=11
                     /translation="MALDGIFLRHIKSEIEKEALGARVSQIYQPNREELVFGLRTFSGN
                     KKLLLSARANSPRVNFCSSTPENPAQPPMFCMLLRKRIGGGKLVGLRQNGCDRVLMLDF
                     ECVNELGDTVMITVVCEIMGMYSNIIIVDSNGVIIDSLKRVDLTMSSKRLVLPNIKYEL
                     PESQNKLNLLKCSVLDVCTAVKNLDTEMPLNKALLRTIEGVSPIVCREIEYKVMEGATN
                     RIEGVLFDRLAVEIEKLKSVCSDCSGKPVVVYREDGKPMDFCFMNVEQYGDFAKVESKE
                     SFSDLLDGFYEARDSRDRMRVKSQSLTKLLNNTLERLARKIAKQKSELERCADREHLRI
                     CGDLLQANIYRIERGAEYVDVENFYDENNAILRIKLNPAISPSANAQKYYKDYRKAKNA
                     EIMLKEQLEKGREELDYINSVLDTVDRAENEKDLAQIREELTEQGYLKVQKGKKPRQTT
                     LPPLEFESSDGFKILVGRNNRQNDKLTLKTASKNDMWLHTKDIHGSHVIVVSDGKEISD
                     TAIYEAARLAAYHSKARNSSQVPVDCTLVRYVSKPNGSKPGMVIYVNNKTLYVKPSQTV
                     E"
     protocluster    1..12770
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9471:12699]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9472..12699
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..12770
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12770
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(1746..2231)
                     /locus_tag="ctg28_2"
                     /transl_table=11
                     /translation="MIKINIICIGKIKEKYFTDAIAEYAKRLTAFCKFNIIELSEERIK
                     SNIPNRSQIDEVIFSEGKRIMQKISPSDYVVAMCIEGKSMSSEELSKLIDNASVSGKST
                     VDFIIGGSYGLDESVKKRADVRLSMSRMTFPHQMARMILSEQIYRAFEISSNGKYHK"
     CDS             complement(2253..3041)
                     /locus_tag="ctg28_3"
                     /transl_table=11
                     /translation="LARAVPLFSGSKGNSYYIGSASEGVLIDAGRSCKQIENAMLANGL
                     DMGSIGAVFITHEHTDHCSALRVLAKRYGFKVYSSLGTLNALRAGNKLDPNTDADVITD
                     EVVIGNMRVQRIDTPHDAAESCCYRVTAPDGKSALIATDMGVMLPDVRTAAEQSDFVVL
                     ESNHDINMLKNGFYPYPLKQRILSNRGHLSNEACAKELVNLVEKGTLRLMLGHLSEENN
                     TVPLAMSTSVDLLTSNGMKYKSDYSLDVATSVSTTKAIIF"
     CDS             complement(3164..4456)
                     /locus_tag="ctg28_4"
                     /transl_table=11
                     /translation="LEKFVVTGGKPLSGEVTISGAKNAAVAIIPAVILCDEPCQIENIP
                     NISDVSLISRILQQMGANVRRINRSSLYIDPTKIRTCNAVTDLVRGMRASYYLLGALLG
                     KYGKAKVALPGGCNFGVRPIDQHLKGFEALGATTQLVDGAIIEAECDNLVGTHVYLDVV
                     SVGATMNIMLAASKAKGQTIIENAAREPHIVDLANFLNSMGADVRGAGTDVIKIRGVEY
                     LHGITYSIIPDQIEAGTYMCAAAATRGCITVKNITPKHLESISAKLREMGVKITEYDEA
                     LKVDASSAPLKRCNIKTMPHPGFPTDCQPQFAALLMSVPGTSIINENVWDNRYQYVSEL
                     IRMGAQISVEGRLAIIEGGVPLTAAPVKATDLRAGAAMIIAALEINGTTEISNIQFIER
                     GYEDVVEKFRGLGADIKKVYFTGDNEQELGA"
     CDS             5187..5504
                     /locus_tag="ctg28_5"
                     /transl_table=11
                     /translation="MENKEKTTTPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENEM
                     SVLNIAEALSMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHVL
                     E"
     CDS             5517..7841
                     /locus_tag="ctg28_6"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCAHCAGKIEAKIAETNGFEDVSFNFATKLLNFKS
                     EKQNPVSEIQAICDSIEDGVTVVDKTPKTNLKKYTYTLDNLNCAHCAGKIEAKIVETDG
                     FEDVSFNFATKLLNFKSEKKNPVSEIQAICDSIEDGVTVVDKTPKNDVTTKAEPEITKK
                     KINHDTIFLAISIVLAVVSEILHLTLDGVTAVHYVVLAACFVATLLSGYKVFIKGAKNI
                     LKLKIDETTLMAVAVIAAFCLGDFVEAAMVTILFSIGEIFEDRAVDASRRDIEKLANIR
                     PDTATIIVDGAEQVVPAESVEIGSIIEVKPYERVPLDGIIIKGKTTLDTSALTGESLPV
                     DADEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDAAAQKGNSEKLISRFASV
                     YTPVVVLIAVAIAVIPPLCGLGAFSEWLYRALVCLVASCPCAIVISVPLSYYSGIGAAS
                     EVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLSVNKVNTVGSYSADEVLALAAASEK
                     YSAHPIASAIRERANGLELPELSDYSESAGHGTSAVYNGKTIQCGGSKILSDEQKKIAN
                     KDDSVFVIYDGQLIGSLNVSDTVRPEAKEVISQLKALGVKNTVMLTGDRQQPAENVKNE
                     LGLSECHAELLPAQKLELFKSLKSKSKGACFVGDGINDAPVLSASDCGIAMGFGSEAAI
                     EASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKALVIILAAFGLAQIWMSVI
                     ADTGVSVVCVLIAARLLKKKY"
     CDS             8040..9275
                     /locus_tag="ctg28_7"
                     /transl_table=11
                     /translation="LKKIFLLLVTALFLLSLYGCNTSSSSNNSTEQTTVTDTDDLSLDT
                     DTDSETEFNYDLEIYYNDKKIDNLNLFDALMPTEDGLIYSKINETSPNEIEYYRYYLDK
                     KNSVKLGSIKNWSMQINDKAYVNNHLCFMASTGDITDEENRTLEFIDIDLNKNKMTTVF
                     SDKGGFPYDTITGADNLVIITKVLNNGTSLELYDTETQKFKQLKYLEFDDKNCVGKTIR
                     KVSIDDKTKTICLLVLDCVSETDVSLKIETYDYDMNFLKSYDISNISDDSNELIQGVQF
                     FDFRNNYLIYQNFSMTRCIGYIGNKKLQKSDMIDNIDDTYSMAQTPQKGYNTVLSFKDV
                     DLERNIYLFNTIDKTMKKTKFKPEEENYYIGSMSRTGKDNLMIITTPDNADKKSNLNPK
                     LYFTKLSDLKFQ"
     CDS             9472..11094
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_8"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.2e-43, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             11107..11598
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_9"
                     /sec_met_domain="ALS_ss_C (E-value: 3.8e-30, bitscore:
                     93.5, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQEPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSSSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             11659..12699
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_10"
                     /sec_met_domain="IlvN (E-value: 5.8e-84, bitscore: 269.1,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4.8e-61, bitscore: 194.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLR
                     DSGCDVIVGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCINPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKLAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
ORIGIN
        1 ttcaaccgtt tgtgacggtt ttacatacag ggttttgttg ttgacataaa tcaccatacc
       61 aggttttgag ccgtttggct ttgacacata gcgaacaagt gtgcagtcaa cgggaacctg
      121 actgctgttt ctcgccttac tgtgatatgc cgcaagccgt gccgcctcgt agattgccgt
      181 gtcggaaatc tctttgccgt ccgaaacaac aattacatga gaaccgtgaa tgtcctttgt
      241 gtgcagccac atatcgttct ttgacgctgt tttcaaagtc agcttatcgt tctgacggtt
      301 gtttcttccg acaaggattt taaaaccgtc gcttgattca aattcgagtg gcggcaaagt
      361 tgtctgacgg ggctttttgc ccttttgaac cttgagatag ccctgctcgg taagttcctc
      421 acgaatttgt gcaaggtctt tttcattttc cgcacggtca accgtatcga gaaccgagtt
      481 aatataatca agctcttccc tgcccttttc aagctgttct ttgagcataa tttcggcatt
      541 tttagccttg cggtaatcct tgtaatactt ctgagcattt gccgaaggtg agattgccgg
      601 attaagcttt atgcgtaaaa ttgcgttgtt ctcatcgtaa aagttttcaa catcaacata
      661 ctccgcacca cgctcaatgc gatagatatt tgcctgtaaa aggtcaccgc atatgcgaag
      721 atgctcacgg tctgcacagc gttcaagctc actcttctgc tttgcaattt ttcgggcaag
      781 cctttcaagt gtgttgttca aaagctttgt aaggctttgt gatttcaccc tcattctgtc
      841 acgactgtca cgagcttcat agaatccgtc aagcaaatcg gagaagcttt ccttactctc
      901 aacctttgca aaatcgccgt actgctcaac attcataaag cagaagtcca taggcttgcc
      961 gtcctcacga taaaccacaa caggcttacc cgaacaatcg ctgcaaacgc ttttcagctt
     1021 ttcaatttca actgcgagtc ggtcaaaaag cacgccctca attctgtttg ttgcgccctc
     1081 cataaccttg tattcaatct cacggcatac aatcggagaa acaccctcaa ttgtccttaa
     1141 cagcgccttg ttaagcggca tttccgtgtc aagatttttt acggctgtac acacatcaag
     1201 caccgaacat ttaaggagat tcagcttgtt ctgcgattcg ggaagttcgt attttatatt
     1261 cggcagtaca agtcttttac tgctcattgt aagatcgaca cgcttgagtg aatcaatgat
     1321 gacgccgttt gaatcaacaa taattatgtt gctgtacata cccataattt cgcatacaac
     1381 agttatcatc acagtatcgc cgagttcgtt cacgcactcg aaatcgagca taagaacacg
     1441 gtcgcaaccg ttctggcgaa gtcccacaag ctttccgccg ccgattcttt ttcgcaaaag
     1501 catacagaac atcggaggtt gtgcaggatt ttcgggtgtt gacgaacaga agttcactct
     1561 cggtgaattt gctcgtgcag aaagcaacag ctttttgttg ccggaaaatg ttctcagccc
     1621 gaacacaagc tcctctctgt tcggctgata aatctgcgac acccttgcac cgagagcctc
     1681 tttttctatt tcacttttaa tatgtcttaa aaaaattccg tcaagcgcca tagtaactcc
     1741 gtaacttatt tgtgatattt accgtttgat gaaatctcaa acgcacggta aatctgttcg
     1801 cttaaaatca ttcttgccat ttggtgaggg aaggtcattc tgctcattga aagacggaca
     1861 tccgcccgtt ttttaaccga ttcgtcaagt ccgtagctgc cgccgataat aaaatcaacg
     1921 gtgctttttc cgcttacgga cgcattgtca atcagctttg aaagctcctc actcgacata
     1981 gactttccct caatacacat tgcaacaaca taatccgaag gcgaaatttt ctgcatgatt
     2041 cgttttccct cagagaaaat aacctcatct atctgcgacc tattcggtat gttgctctta
     2101 atgcgttctt ccgaaagctc aataatattg aatttacaaa atgcggtcaa gcgttttgca
     2161 tactctgcaa ttgcgtcggt aaaatatttt tctttgattt tgccgataca aattatgtta
     2221 atcttaatca tattcctctt gtttgtttaa ggttaaaaga tgatggcttt tgttgtgctt
     2281 acactcgtag caacatcaag cgaataatcg cttttgtact tcattccgtt tgatgtgagc
     2341 aggtctacgg atgttgacat tgcaagcgga acggtattat tttcttcgct gagatggccg
     2401 agcataagtc ttaaagttcc cttttcaaca aggttaacaa gttcttttgc acatgcctca
     2461 tttgaaagat gtcctctgtt tgaaaggatt ctctgcttta gcggataagg ataaaatccg
     2521 tttttgagca tattgatatc gtgatttgac tcaagcacaa caaagtcgct ctgctctgcg
     2581 gcagttctga catcgggcaa cataacgccc atatcggttg ctataagtgc ggattttccg
     2641 tcgggagcag taacacggta acaacagctt tctgccgcat cgtggggggt gtcaattcgc
     2701 tgaacacgca tattgccgat tacaacctcg tcagttataa catctgcatc tgtgtttgga
     2761 tcaagcttat tacctgccct caaagcattg agcgtaccaa ggcttgaata caccttaaag
     2821 ccgtaacgct ttgcaagcac acgcaacgca ctgcaatggt cagtgtgttc gtgagttata
     2881 aaaaccgccc cgatactgcc catatcaagt ccgtttgcaa gcatggcatt ttcaatctgc
     2941 ttgcatgaac gacctgcgtc aatcagtacg ccttcgcttg ccgaacctat gtagtagctg
     3001 ttacccttac ttccgctgaa cagcggtact gctcttgcca aaacaatcaa tccttatctt
     3061 tagtataacg aatatgataa cacaaatttt aaaatttgta aattatctca caaaaaagcc
     3121 gttctcacaa agaaaacggc tttgatttct aattaaattt tagtcaggca ccgagctctt
     3181 gctcgttgtc tcctgtaaaa tacacctttt tgatatctgc accaagtcct ctgaactttt
     3241 caacaacatc ttcatatcca cgctcaatga actgaatatt tgagatctct gttgtaccgt
     3301 taatttcaag agcggcaata atcatagccg cacctgcacg aagatcggtt gccttaacgg
     3361 gagccgctgt gagcggaaca ccgccctcaa tgattgcaag tctgccctca acagaaatct
     3421 gcgcacccat tcttataagc tcgctgacat actggtagcg attatcccaa acattctcgt
     3481 tgatgatgct tgttccggga acgctcataa gcaatgcggc aaactgcggc tgacagtctg
     3541 tcgggaagcc gggatgcggc attgtcttga tattacagcg cttgagcgga gcagatgacg
     3601 catcaacctt gagagcctca tcatattccg taatcttaac acccatctca cgcagctttg
     3661 cgctgattga ttcaagatgc ttcggtgtaa tattctttac cgtaatacaa cctcttgttg
     3721 cggcggcggc acacatatat gttcctgcct caatctggtc gggaataatc gaataagtaa
     3781 tgccgtgaag atactcaacg ccacggattt tgataacatc cgtacctgcg cccctgacat
     3841 ccgctcccat tgaattaagg aagttcgcaa ggtcaacaat atgcggttct ctcgcggcat
     3901 tttcaataat ggtctgtccc tttgcctttg atgcggcaag cataatgttc attgttgcac
     3961 caacggacac aacatcaagg tacacatgtg taccgacaag gttgtcgcat tctgcctcta
     4021 taatcgcacc gtcaacaagc tgagttgtcg caccgagagc ctcaaagcct ttaagatgct
     4081 ggtcaatcgg acgcacgcca aagttacagc cgccaggaag agccacctta gccttgccgt
     4141 acttgcccaa aagtgcgccg agaagataat atgacgctct catacctctt acaaggtcgg
     4201 tcacagcatt gcatgtgcgg atttttgtag gatcaatata taaggacgaa cggttgattc
     4261 gtcttacatt agcacccatc tgctgaagaa ttctgctgat aagtgataca tcgctgatgt
     4321 taggaatatt ttcaatctgg cacggttcat cacaaagaat aactgccgga ataattgcaa
     4381 cggctgcatt tttcgcaccg ctgattgtca cttcacccga taatggcttt ccgccggtaa
     4441 ctacgaactt ctccaattgt tacaccccaa ttaatgtgta gaagatactt ttaactaaat
     4501 aagctaaata tctgaaaatg tatatctata tagtgtataa gtaaaaatca aaaattatac
     4561 gaatctaaaa ttcataatga gaactaattt gttacatttt attaaaaacg aacccactcg
     4621 gttacgcaga tgtaatttaa caattctctt acagaaaatg atactacaaa attgtagtaa
     4681 agtcaacgga ataataaaac tgtaatctat ttttgggcaa gttgtactca aattattaat
     4741 ttgttgcttt ttttgttttt aatataacca accatgcttt ttaaaaccgt tttttcctaa
     4801 aaagaagtaa ttaatcaaag caattttttg taaaattatt acaaattgaa acaagtttta
     4861 ttttcgtgtt atcatcaggc atctgagcaa tttacaattc aaattgaaca cagaaaaata
     4921 tcgttccatt attcctacga taattttaca ccttcaatct tcttttttca aatttaaaat
     4981 taactttcta tactatatat actttccaaa cggacacaat aaacaagtga aactttgggg
     5041 caaaaaaact tgaaaaacat tacatttttt cgtgtgtgtc tattgacttt ttaaaaaggg
     5101 aatgctatat tataattaac atatgagcat atcttcatat gttcaagtgt gactattaac
     5161 ctgagagaaa attaaagggg acgcctatgg aaaacaaaga aaaaacaacc actcccgaaa
     5221 tgcccgacat tgatgtgctg tttgagcttg cagacctttt taaggttttc ggtgattcaa
     5281 cccgacttcg cattatgtac accatttcgg aaaatgaaat gtcggtgctc aacattgctg
     5341 aagctctcag catggagcaa agcacaattt cccaccaact gcgtgtgtta aggcagaaca
     5401 agctggtgcg tgttcgccgt gaaggaaagc agatttatta cagccttgac gatgaccatg
     5461 tgaaacgaat catagaaatg ggacttgacc atgttcttga ataaggaggg agacatatga
     5521 ggtacaaata tcagcttgac aatctcaatt gtgctcattg tgcgggcaag attgaggcta
     5581 aaattgcaga aacaaacggc tttgaagatg taagcttcaa ttttgcgaca aaacttctca
     5641 atttcaaaag cgaaaagcag aatcctgttt ccgaaattca ggcaatttgc gacagcattg
     5701 aggacggtgt aaccgttgtt gacaaaactc cgaaaaccaa tctcaaaaaa tacacctaca
     5761 ctttagacaa tctcaattgt gctcattgtg cgggcaaaat tgaggctaaa attgtagaaa
     5821 cagacggctt tgaggatgta agctttaatt ttgcgacaaa acttctcaac ttcaaaagcg
     5881 aaaagaagaa tcctgtttcc gaaattcagg caatttgcga cagcattgag gacggtgtaa
     5941 ccgttgttga caaaactccg aaaaatgatg tcacaacaaa ggcagaaccc gaaatcacga
     6001 aaaagaaaat caaccatgac acaatcttcc ttgcaatttc aattgtactt gctgtagtgt
     6061 ctgaaattct ccaccttaca cttgacggtg ttacggctgt tcattatgtt gtactcgcag
     6121 cgtgttttgt tgcaacactt ctttcgggtt acaaggtatt tatcaagggt gcaaaaaaca
     6181 ttctaaagct gaaaattgac gaaacaacgc ttatggctgt tgcggtaatt gcggcattct
     6241 gtcttggaga ttttgttgag gcagcaatgg taacaatcct cttttctatc ggtgaaattt
     6301 ttgaggatcg agcagttgac gcatcccgcc gtgacattga aaagcttgca aacattcgtc
     6361 ccgatacagc aacaattatt gttgacggtg cggaacaggt tgttcctgcc gaaagcgttg
     6421 aaatcggaag tatcattgaa gtcaagccat acgaaagagt tccgcttgac ggcattatta
     6481 ttaaaggtaa aacgactctc gacacatcgg ctctcacagg cgaaagcctt cctgttgatg
     6541 cagacgaggg cagtgaggta ctcagcggcg caatcaacgg cagtaacctt attactgtca
     6601 aaaccacaaa gcatttcggc gacagtaccg caacaagaat tcttcagctt gttgaagatg
     6661 ccgccgctca aaagggcaac agcgaaaagc ttatttcaag atttgcctct gtttacacac
     6721 cggttgttgt actcattgca gttgcaatcg cagtaatccc tccgctttgc ggactcggag
     6781 cattcagcga atggctctac cgtgcgcttg tttgtcttgt agcctcatgt ccgtgtgcta
     6841 ttgttatttc cgtacctctc tcctactatt cgggtatcgg tgcggcatcc gaagtcggtg
     6901 tactcatcaa gggcggaaaa tatattgagg ctcttgcaaa agcagacaca ttcgtattcg
     6961 ataaaacagg cacactcaca agcggcaagc tcagcgtaaa caaggttaat acggtcggtt
     7021 catacagtgc tgacgaagtt cttgctcttg ccgctgcaag cgaaaaatat tctgctcatc
     7081 cgattgcctc cgcaatcaga gaaagggcaa acggtcttga acttcccgag ctttccgact
     7141 acagcgaaag tgccggtcac ggaacaagcg cagtttataa cggcaaaact attcagtgcg
     7201 gcggttcaaa gattctttcg gacgaacaga agaagattgc aaataaagac gattctgttt
     7261 tcgtaattta tgacggtcag cttatcggtt cgctcaatgt cagcgataca gtaagacctg
     7321 aggcaaaaga ggttatctca cagcttaaag cgctcggtgt caagaacacg gtaatgctca
     7381 caggcgacag acaacagcct gccgaaaatg ttaaaaacga actcggactt tccgaatgtc
     7441 acgcagagct tctccctgct caaaagcttg agcttttcaa gagcttgaaa tcaaaatcca
     7501 agggtgcttg ctttgtgggc gacggcatca atgatgcccc tgttctttcg gcaagcgact
     7561 gcggtattgc aatgggattc ggcagtgaag ccgctattga agcgtcagac gcagttctcg
     7621 catcaggcac actcaaacag cttccaaagg caattaaaat tgcaagaagt gttatcaaca
     7681 ccgtcaaggg caacatcatc tttgccctct caatcaaggc tcttgtaatt atcctcgccg
     7741 cattcggtct tgcacaaatc tggatgtctg ttatcgccga cacaggcgtc agcgtagtct
     7801 gcgtcctcat agccgcaaga ctcctcaaaa agaaatattg atttttttgc aaatcatatc
     7861 atttattatg ataaagcacc gtgagctttc acaagtttca cggtgctttc atttgccaaa
     7921 atttttctaa acataatctt atattatagt attttaaaat cattgacttt tataattata
     7981 taaattataa tgtttttgtc agcgcttgta actgataaat aaacttcgga gagattaatt
     8041 tgaaaaagat atttttatta ttagtaaccg ctttattttt actttcatta tatggatgta
     8101 acacttcttc atcaagcaat aattctactg aacaaacaac cgtaacggat acagatgatt
     8161 tatctcttga tacagataca gattctgaaa cagaatttaa ttacgatttg gagatttact
     8221 ataacgataa aaagattgat aatttaaatc ttttcgatgc acttatgcca actgaggatg
     8281 gactcatata ttcaaaaatc aacgaaactt ctccgaatga aatagaatac tacagatatt
     8341 atttagataa aaaaaacagt gtaaaacttg gttcaataaa aaactggtct atgcaaatta
     8401 acgataaagc gtatgtaaat aatcacttat gttttatggc aagcacgggt gacattacag
     8461 acgaagaaaa cagaaccctt gaatttattg atatagacct taataaaaac aaaatgacta
     8521 ctgtcttttc tgacaaaggc ggttttccct atgataccat tacaggtgca gacaatcttg
     8581 tcataattac aaaagtatta aacaacggta cttctttgga actgtatgac accgaaacgc
     8641 aaaagtttaa acaactgaaa tatttagagt ttgatgataa gaactgtgta ggaaaaacta
     8701 taagaaaagt ttcaattgac gacaaaacaa aaacaatctg cctcttggtt ttggactgtg
     8761 tttcggaaac agatgtttct ttaaaaatag aaacctatga ctatgatatg aattttctta
     8821 aaagctacga tatctccaat atttcggatg attcaaatga actgattcaa ggtgtacagt
     8881 tctttgattt tagaaacaac taccttatct atcaaaattt tagtatgaca agatgtatag
     8941 gttatatagg gaacaaaaaa ttgcaaaaat ccgatatgat tgacaacatt gacgacacct
     9001 actctatggc tcaaactcca caaaaaggat ataatacagt tttatcattt aaagatgttg
     9061 atttagaacg gaatatatac ttatttaata ccattgacaa aacaatgaaa aaaacaaaat
     9121 tcaaacctga agaagaaaac tactatatcg gctcaatgtc aagaactgga aaagataatt
     9181 tgatgataat aactactcct gataatgcag acaaaaaaag taatcttaat ccaaaactat
     9241 actttacaaa attaagcgac ttaaaatttc agtaaacagg cggtaaaaat caattaaaat
     9301 tcattttgca aattatctgt caaaatcctg caaaaaattt aatttatggg caatactgct
     9361 ctttactttt taaggtattt attgtataat tagcggtaaa gtaaaaaggt atatttaatg
     9421 ttacaaaaca ccttttgctc acaataaaaa ggataggagg gacaaaacat aatgatcagc
     9481 ggtgctgaaa ttatggtaaa atgtttggaa gccgagggcg ttgacatagt ctttggttat
     9541 cccggtgcgg ctatctgccc attttacgat aaagtttacg attcgagcat tacccacatt
     9601 cttgttcgtc aggaacagaa cgctgctcat gcggcaagcg gctatgcaag atgcagtaat
     9661 cgtcccggtg tttgcgtggc aacttccggt cccggtgcaa ccaacctcat cacaggcatt
     9721 gcaaccgcct atacggactc tattccgatt gttgccatta caggtcaggt tcgttctgac
     9781 cttctcggca gagatgtctt tcaggaagct gacatcacag gagcttgtga accgtttgta
     9841 aagcacagtt atctcgtcag caaaacagaa gaccttccga gagttttcaa agaggctttc
     9901 catattgcct caaccggcag acccggtcct gtacttatcg acattcccgt tgatattcag
     9961 gaaaatgaaa ttgaaagttt tgaatatccc gaaagcgtaa acattatcgg ttacaagccg
    10021 aacactaagg gacacgcaat tcaggttaaa aaggctgttg aggccatcaa cgcaagcaag
    10081 cgtcctgtta tcgtatcagg cggcggcgtg ctgagttcgg gtatcaagct taaacttcaa
    10141 aaatttgcag aaactacggg tatccccgtt atttcaacta tgatgggcat cggtgttatg
    10201 cccagcgagc atgagcttta tctcggaatg ctcggcactc acggcaaggc tgttgccaac
    10261 cgtgctcttc acgaagccga ccttgtaatc gtatgcggtg caagactcgg tgacagagct
    10321 gttgcggctc ccgaccagat gagtgaaaac acaaaggtaa ttcacattga cattgaccct
    10381 gctgaaatcg gtaagaatgt taaaacagaa attccgattg taggcgatat gaaaaatgtc
    10441 atcaatatgc tgcttgacag catcggcgat tacaaggtta caacaatgtg gagcgaaacc
    10501 gtaaagaact ggaaaaaaga cctttaccgt gagcctcccg tttttgacgg ctttgttgag
    10561 ccgagaacac ttgtcggtca tctcagtgca atgttccgct caaaggcaat tcttgttgcc
    10621 gatgtaggac aaaatcaaat ctggtgcgca aacaacttcc gtattcgtga gggcagattc
    10681 ctcacaacag gcggtatggg tacaatgggt tactcaattc ccgctgcaat cggtgcaaag
    10741 tttgcaagac ccgaccgtga tgttattgta atctgcggtg acggcagttt tcagatgggg
    10801 cttaatgagc ttgcgactat tgcaggcaat cagctcggaa ttaaaatcat cattatgaaa
    10861 aacgcacgac tcggaatggt tcgtgaactt caggacaaac actacggcgg cagacactcc
    10921 gcaacaattc tcaacggtga tcccgacttc ttgaagattg ctgatgctta cggcattgac
    10981 catgcagagg ctcattcaaa caaggaagcc gaaaacatca tcaagggtat tgttgattcg
    11041 gaaaaaccgt tcattcttgt ttgcgatgtt caccctgaca ctccgtcaat ttaatgaggt
    11101 gataaaatgc agtatacatt atcaatactt gttgaaaatc aggcgggcgt tctttcaaag
    11161 atttcgggac ttttctctcg ccgaggtttt aacatcgact cactcgcagt aggtgttact
    11221 caggaaccgt cggtttcccg aatcacaatc gttgcaaacg gtgacgagta cattgttgaa
    11281 cagcttgaaa aacagcttaa caagctcatt cccgttatta aggtaaaaag gcttaacgag
    11341 ggcgaattta tcagccgtga gcttgtttta atcaaggttc actgcgccgc ctcaaaaaga
    11401 gccgaaattg tcaaaacggt tgaaattatg caggcgaaaa tcgttgatgt atcctcttcg
    11461 tcagttaccg ttgagtactg cgaatgtgca agccgcatca acacgcttgt tgacttactc
    11521 aagccttatg gtatccgtga gattgtaaga acaggtactg ttgccatcga cagaggcaca
    11581 gcttcggttt ccgtttaatc ttacagttag catatatttt aatttatatg ccgcgtttgc
    11641 ggtaaggagg actttaatat gaaagactac acaaaaaaca tgacagcacc aatctactat
    11701 cagtcagatt gcaaccttga ccttctcaag ggtaagaaaa ttgctattat cggttacggc
    11761 agccagggtc atgcacacgc tctcaacctc agggattcag gttgcgatgt aatcgtcggt
    11821 ctttacaaag gcagcaagag ctgggcaaag gctgaagcac agggctttaa ggtatataca
    11881 tcagcagagg ctgcaaagca ggctgacatc atcatgattc ttatcaacga tgaaaagcag
    11941 gcagctcttt acaagaacga catcgagcca aacctcgaag caggcaatat gcttatgttc
    12001 gctcacggct ttaacattca cttcggttgc atcaatcctc caaaggatgt tgatgttaca
    12061 atggtagctc ctaagggacc gggtcacaca gttcgttcag agtatcaggt tggtaagggt
    12121 gtaccttgcc tcgttgctgt tgagcaggat gctacaggtc aggctaagga tctcgcactt
    12181 gcatatgcac tcggtatcgg cggtgcaaga gcaggtgttc ttgaaacaac attcagaaca
    12241 gaaacagaaa cagacctctt cggtgaacag gctgttcttt gcggcggtgt ttgcgcactt
    12301 atgcaggcag gttttgaaac actttgcgat gccggttacg acccaagaaa tgcttacttt
    12361 gagtgtatcc atgagatgaa gctcatcgtt gaccttatct atcagtcagg ttttgcaggc
    12421 atgagatatt caatctctaa cacagctgag tacggtgact acatcacagg tccaaagatc
    12481 atcacagagg atactaagaa ggctatgaga aaggttcttt ctgacattca ggacggtaca
    12541 tttgctaagg acttcctcct tgacatgagc gatgccggtt cacaggttca cttcaaggct
    12601 atgagaaagc tcgctgccga agctcctgcc gaagtattcg gtaaggaagt tagaaagctc
    12661 tacagctggt ctgacgaaga taagctcatc aacaactaat gttttttagt tcgtgaagtt
    12721 agtttgatat attcaaactt ctgtcacccg agcattacat agtacgaatt
//
