LOCUS       c00015_gnlPro..        13916 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IGKMMPLI_15.
ACCESSION   c00015_gnlPro..
VERSION     c00015_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 16:10:41
            Original ID  :: gnl|Prokka|IGKMMPLI_15
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13916
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13916
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[426:3916]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      427..3916
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13916
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13916
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(427..1257)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_1"
                     /sec_met_domain="Fer2_3 (E-value: 1.8e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 5.7e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.1e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1235..3166)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.2; E-value:
                     4e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.6e-54, bitscore:
                     176.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 7.6e-38,
                     bitscore: 120.9, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVLVVGSGLAGA
                     SAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKGGD
                     FRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRTFYARGQTGQ
                     QLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEIKSYAGDTVL
                     LCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVKGDYQSKLTL
                     MSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFGNLAPRDISS
                     RAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEITDDDPHETP
                     MMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQGLSDGYFVI
                     PATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFHRELGLIMWE
                     DCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVADFLEFAQLLC
                     YDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLHKEPLTFENV
                     HLAIRSYK"
     CDS             complement(3215..3916)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_3"
                     /sec_met_domain="SucD_FumR (E-value: 1.7e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             4117..4389
                     /locus_tag="ctg15_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4392..5207
                     /locus_tag="ctg15_5"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPTRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5241..5648)
                     /locus_tag="ctg15_6"
                     /transl_table=11
                     /translation="MQSPASLSIRNSPSFQQSISPHGPDRCGSVRRQQTPSPKQGKGVG
                     KWLSLNLYPPFPSMNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPDE
                     FLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5903..6610)
                     /locus_tag="ctg15_7"
                     /transl_table=11
                     /translation="MKKLLSTLILSAGMSLSATANTTLLDSSIVGYSDFTSQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGTNNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYF
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             complement(6641..6730)
                     /locus_tag="ctg15_8"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKRKCIH"
     CDS             complement(7156..7452)
                     /locus_tag="ctg15_9"
                     /transl_table=11
                     /translation="MPGAVNPPLIVTVSPSVLAVGAAVPPAAYKYVLDVSCIKSITDWL
                     TARKRYVNAASRSRGEPSREEKLNVRLIPAAVVPVLVLQPMTELSEPFSTRKP"
     CDS             complement(7863..7997)
                     /locus_tag="ctg15_10"
                     /transl_table=11
                     /translation="MYAAALQVCELQRGSLSGLKGHYVKAAVYHMDEKRAAEFDGIFR"
     CDS             complement(8109..8309)
                     /locus_tag="ctg15_11"
                     /transl_table=11
                     /translation="MTIALRTEQSSDHAETEHVTREAFWNYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             complement(8323..9171)
                     /locus_tag="ctg15_12"
                     /transl_table=11
                     /translation="MGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENGR
                     PRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCEW
                     LSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSKK
                     PNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPDS
                     LRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKGE
                     P"
     CDS             complement(9552..10481)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_13"
                     /sec_met_domain="adh_short_C2 (E-value: 3.3e-75, bitscore:
                     244.0, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTGRPPVHSGKMKRPDSSPPPRFSPLFFHSRHAPSPYGFLRGQV
                     HFKLAGTVKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSC
                     GGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLR
                     MKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKA
                     GLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDI
                     AALTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10426..10944)
                     /locus_tag="ctg15_14"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             complement(11008..12555)
                     /locus_tag="ctg15_15"
                     /transl_table=11
                     /translation="MTINWGERVALVGPNGAGKSTLFRMILGEDTPDEGSISMDEYAIV
                     GYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAENANKTDTPEYAEAIDTFNAANG
                     YQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYLAKLLVLEPDLLMLDEPTNHLD
                     LLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDIDNEELVEYRGNYSDFLQQKDV
                     RFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQSRIKQLEKMKIIQKPVARRKVF
                     KFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVERGERTVLVGPNGAGKSTLLKI
                     LAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVLEEIMKCSAEIREEEARSILGS
                     FLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLMDEPTTHLDLLSVEALVQALKH
                     YEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYDYYLEKSGILDDEKGGITAE"
     CDS             12741..13448
                     /locus_tag="ctg15_16"
                     /transl_table=11
                     /translation="MPTTQTFRLLLAAALLCGWSSCCTPPAEDYIQQTYVQQQMSGLAN
                     AFLALLPPDQASLPAAGAEARWLAETAVVQSAAIARDNRTVLFGWLNNILVNSNLRDRG
                     LCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCVYVNAAGKGLQGSIVLDAWKN
                     CGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGMEHHLVWPGWARKRPILVQRIF
                     QSDQQNEAKAAAE"
ORIGIN
        1 ttaagaacat gagaatttat tccatgagaa aataatatta taattcttac gctcagtgca
       61 ttcccttaat agacatcaat gttgtctgtt tgttagaaaa tgttttcctc tcatgctgag
      121 cccttgacag gatgccatcc cttccgggca tcagtctaat tcctgtaatc aatgtttttc
      181 tctctcggag aaagatgggg ccgtcgctgt cggacggggc ctgcttaggt ttcgtccggc
      241 atttccaagt acggtttcct ggattactgg gtgccttccg gtgtaacaat tttttacgct
      301 gcgcgacgat gaggaagcaa ctgtctggta ttttattcct ggttcaagga aatctggtaa
      361 tgaaaaaact cccgacagcc gatgccgccg ggagttttta cagagcgtct taagaaggaa
      421 tcttctttag aaacagaggc cttccttggc gttggcccgc atgaagtcgc ggttgaggcg
      481 ggcgatgttg tccacgctga tgcctttcgg gcaggcggct tcacattcat actggttcgt
      541 gcagttgcca aagccttccg cttccatctg cttcatcatg gccaggacgc gcttggaacg
      601 ttccggctgg ccctgcggca gcagattgag atgggcgatc ttggcggagg tgaacagcat
      661 ggcggaagcg tttttacagg aggccacgca ggcgccgcag ccgatgcagg cggccgcgtc
      721 aaaggcggcg tccgccttca ctttttccac ggcgatgttg ttggcgttcg gcgcggaacc
      781 ggtacgcacg tcaatatagc ctccggcggc gatgatgcgg tccagggcgg agcggtccac
      841 catcaggtcc cgcaggattg ggaaagcctt cgcgcggaag ggttcaatcc agacggtatc
      901 gccgtccttg aacttgcgca tgtgaagctg gcaagtggtc acctggcgtt ccggcccgtg
      961 gggaatgccg ttgatggtca gggagcacat gccgcagatg ccttcccggc agtcgtggtc
     1021 aaaatggatg ggttccttgc cttccttgac caggccttca ttgacgatgt ccagcatttc
     1081 caggaaggag gcgtccaccg gaatgtcctt ggcggcatag gtctcaatgc ggcccttggc
     1141 ttcccggttt tcctggcgcc agaccttgag agtgagattg agtgttttag ccatgttata
     1201 atctttcttt tgagtgttaa tgtattggct atctttactt gtagctgcgg atggcaaggt
     1261 gcacgttctc gaaggtcagc ggttccttgt ggagaacagg caggctgtcc acgccagtgt
     1321 attcccaggc ggctacatag gcgtattcat cgtcgttgcg cttggcttcg ccgtccggca
     1381 gctggtattc cacgcggaag tgggcgccgc aggattcctg gcggttcagg gcgtcatagc
     1441 agagcagctg ggcgaattcc aggaagtcgg ccacgcggca ggctttttcc agttccgcgt
     1501 tgatgccgtc cgccgtgccg gttacgcgca cgttttccca gaattccttg cggagctggg
     1561 gaatgcgttc aatggcgtgg gtcaggcttt cttccgtgcg ggccatgccg cagtcttccc
     1621 acatgatgag gcccagttcc cggtggaagg agtccaccgt cttggtgccc ttcacattca
     1681 ggagcttgtt gatgcgttcc ttcacttcgt cttccgcagc cttgaattcc ggggcggcgg
     1741 tggtgacggc gccgggcttg gtggtcgtca ggtaagcggg caacgtggcg ggaatgacga
     1801 agtagccgtc agacaggccc tgcatcaggg cggaggctcc caggcggttg gcgccgtggt
     1861 cggagaagtt ggcttcaccg aggacgtgca gccccttcac gttggacatg aggttgtagt
     1921 ccacccacag gccgcccatg gtgtagtggg aggcggggta gatcatcatg ggcgtttcat
     1981 gggggtcgtc gtccgtgatt tcttcgtaca tgtcaaacag attgccgtat tggccgtcaa
     2041 tccattcgcg gcccatgcgc ttgatttcat ccgcaaaatc caggaagacg cccttgccgg
     2101 tgacggccac gccgcggccg tcgtcgcagg cttccttggc ggcgcgggag gaaatgtcgc
     2161 gcggagccag gttgccgaag gagggatact tgcgttccag gtagtagtcc cgttcttctt
     2221 cgggaacatc ggaaggcttg atttcctttt tacggatttt ttctgcggtt tcacgggact
     2281 tgggcaccca gatgcggcca ctgttgcgga gggattccga catcagcgtc agtttggact
     2341 ggtagtcgcc cttgaccgga atgcaggtgg ggtggatttg cgtgaagcag gggttggcga
     2401 agaaggcacc gcgcttgtag gccttgtagg cggcagtgac gttgcagccc atcgcgttgg
     2461 tggacaggaa gaacacgttg ccgtagccgc ccgtgcagag caggacggta tcccctgcgt
     2521 aggatttgat ttcgccggta accagattgc gggtgacgat gcccttggct tcgccgtcca
     2581 ccagcaccag atccatcatt tcatggcggg agaacatttc aatgtgtccc ttggccactt
     2641 ccttttccag ggcctggtag gcacccagca ggagctgctg gcccgtctgt ccgcgtgcgt
     2701 agaaggttcg cttgagctgg gcgccgccga aggagcggtt gtccagcagg ccgccgtatt
     2761 cacggccgaa gggaacgccc tgggccacac actggtcaat gatgttggag gagacttccg
     2821 ccagacggta gacattggct tcacgggcgc ggaagtcgcc gcctttaacg gtgtcgtaaa
     2881 acaggcggta aacggagtcg ccgtcgttct ggtagttctt ggctgcgtta atgccgccct
     2941 gggccgcaat ggagtgggcg cggcgggggc tgtcctggta gcagaagcat ttgacgttgt
     3001 agccaagttc ggcaagcgtg gcggcagcgg aggcgccagc caggccggaa cctaccacaa
     3061 gcaccgtgta cttgcgcttg ttgttcggat tgatcagttt ggactcaagt ttgtacttgg
     3121 accatttgtc ctgaataggg ccggagggaa ttttggcatc cggcatccag tcgcttacgg
     3181 gaaaattaat catgactttg agaggagttg atggttattt gatgataccc agaagaaccg
     3241 agaccggcac ggagatgaag cccaggcaga taatcgcgcc gtaggcgatg gcgataaagt
     3301 tgtagaaggg ccggattttg cgggaatcga cgcccacagt ctggaagatg gactgtaccc
     3361 cgtggcgcag atggctgaac agcatcagaa cggccaggat gtagaaggcg gagcaccata
     3421 cgttggagaa tccggtcacg atcatcttgt acacgtcaaa ggtttccacc gtaccgtcgg
     3481 aaataaaggt ggtgaactgg gcggggtcgt atcccacgcg cagggtgtac tggtacaggt
     3541 ggtagatcag gaacaccagg acggtcaaac cggtatagat catgtagcgg gaggagagcg
     3601 ttgccttaat ggtgttcttg aacacgtagg gttcgcgggc cgcatggttt tccagcttca
     3661 gctggatggt cagccagacg tggatgatga agatcaccgc aagccccgcg cggattcccc
     3721 agagggctgc ttccggcatg gagtgcaggc cgtgggcgta ggtgttgatc cattcagggc
     3781 ctccgaagat gagaaggttg cctgccaggt gtcccgcaag gaacaagacc aaacataacc
     3841 ccgtcagagc cacaatgatt ttgcggccga tggaggatgt cacgaatgta catatggttt
     3901 ttactagtgc attcataggc gctctaatga aataaatgcg tcttcacagg atgcccggtt
     3961 caagcccgga tggcaagcct cttcttgaat ttccggcgct tttcggattt ttgaaaaacc
     4021 ggggaaagag gttgctgttt atcagtttgg aatggttatc attttgttgc ctgttccggc
     4081 ttgacgaggc tttccgcata ggcgtatcgt ctgtgcatga aaagaagtaa aaaggaggtg
     4141 ctggacgcgg atttcgcagc ggcgcgcgcc ggcgttctgg atgtggccgc atttctggac
     4201 cgggtggacc gcggggaagg ggaggcggat ttccgctacc atgccctgat ggatgttctt
     4261 cccctcttgt ccgcatccgg ccccggacgc gtccgggcca ttctggaagc cctttcctac
     4321 agggatgaca ccgtgccgga aaccgccgca gccaaagcgg cctgcggagc cccgaacctc
     4381 agcaaataag aatgatggct ttcatagaac ctcatataca tatggtgtgc cgcaccacgg
     4441 acgaataccg ggccatggcg caggccggct gcctggcggt aggggaaccg gcgttctggg
     4501 ccggttacga ccgttcgtcc gcggacggtt tccgggatta tttcgtacag cttacggaat
     4561 gcgaacccgc cagggcggcc aagttcggca tggaccatta cacatggctg tgcatcaatc
     4621 ccaaggaggc gcaggacgtg gctttcgcgc gggatgtgat gaaactgatt ccggagttca
     4681 ttgaccggcc caatgtcctc ggcatcgggg aaatagggct gaaccggaat acttcccatg
     4741 aaatgactat ttttgaagag catctggatc tggcggtgcg cctcaaccag cttgtgctga
     4801 ttcacactcc ccatctggaa gacaagctta aggggaccgt aatgattctt tccgccctga
     4861 aaaaccgtcc ggatctggac ccttgccgcg tgctggtgga tcactgtgag gaacatacct
     4921 tcccgctggt gaaggaggcc ggttactggg ccgggctgac cctttatccc accagtaagc
     4981 tgaatcccac gcgggcggcg gatattctgg aattgtacgg aatggaccgt gtctgggcca
     5041 attccgcggc ggactggggg gattccgatc ccctggcgct gacggccctg gcctgcgagc
     5101 tgcgcaggcg cggtttttcc cggcaggaaa cggaacgtct tctcctggaa aatccggaga
     5161 cattcatggg acagtccccg aagttccgga aagtgtcgtc ccgctaattc cgcccgaggc
     5221 gcggcggagg gtacggccct ctagtccccg tccgggaaaa agacggtgag gacggcgccc
     5281 aggatgaccg ccgcgtcatc cagaaggccc agcctgccga ttccgtcaaa caggaattcg
     5341 tcgggagtca ggatgtaggc gccggcggcg gccagaaggc atatattccg tttgttgaaa
     5401 aaacgcggtt ctccttttct gcttttgaaa taccggaaca ggcgcagtag cagttgctgt
     5461 ttttgaaggt tcatggacgg gaacggggga taaaggttca agctcagcca ttttcccact
     5521 ccttttccct gtttcgggga aggagtctgt tgccgacgga cggaaccgca gcgatccgga
     5581 ccgtgcgggg aaatggattg ctgaaaggat gggctgttcc ggatgctgag ggaagccggg
     5641 ctttgcatgc tccggttccg gctgtcccgg catgggaaaa aggggcgtgt acggaagtgg
     5701 ggcggggccg gaagctcttg aaatgaccct accgggggag actgaatgcc atttttccgt
     5761 caagtgctgg ccgtgaggtt gccgcagcaa atggaagctt ttcccctctg ttttttcggc
     5821 agatgtttga acggataagg aaaaggccgg ctcacgattt tgtgagccgg cctttgaata
     5881 tagggaggcg gacggtacag gcttatgccc tgcggcggcg catcatcagc gcggccagtc
     5941 ccagcaggcc cagggaagcc gtggcgggtt ccggaatgct ggcgatttca ctcatcagtt
     6001 gaccaacttg ttcctgggaa aggagggagt cgtggatgta gagctgttcg atggattcag
     6061 ccagtcctgc gtccatgaga atctgatcaa tttgctggtt gccgaatttc aggccgctgt
     6121 tgaaatagta cgtagcgctg tcgccaaaat agatgcgggt gccaagatct ccggtgacta
     6181 cggaaatggt cagggaccct tccgtgccca gcggggtgtc aacgacgggc ccgctgtatg
     6241 aggtgttgtt ccataatccc tggagtttcc ggtccgtgtt caggcccacg ccccagctta
     6301 cactgctgtt tttggcgtta aacagagcgg tataggtctc cggagtgttg attttggaca
     6361 gatcaagaac catcgtcaca gacataacgt cgcggttgtt ggtaccgtat ccgttgaagg
     6421 ttatcccgga taacgtcaga ttgctgtcgt cagacgtgat ggaaacggaa tctttcaggg
     6481 tgccgaaatc cgccgtttgg gaggtaaagt ccgaatatcc cacgatagag ctatccagca
     6541 gagtggtatt cgcggtggcg ctcaggctca tgccggccga aagaatcagg gtggataata
     6601 atttcttcat ggtcagtatc ttaataaaat gatgcaagat tcaatgtatg cacttgcgct
     6661 tgaataacga atttggaatc cgcaagcaat taaaaatatt aagagttagt atattgtatt
     6721 tataattcat tgaaaataat gattttttaa tatctctggt ccttttgtca agatgacggg
     6781 gcaatctttg ttattcattg gtttcatgat tgatttggcc tctttttcat tacttgacgg
     6841 attccaaatc cgattgggga attccaaatt cgctacaagt tgccatccaa aaggaataat
     6901 aaatatgaag aaaacactga catttttaat cgcgatggga aactttgctg tttcctcgga
     6961 ggcagcgacc gtttttaatt attacactcc cggtacggat aattacaata gtaccatcca
     7021 tgggttttat cttggcctgg ggtcttcttc cctggctcct tccgattcct cttctccctc
     7081 ctccctgtcc ggagagatca gactggacag ttttacgctg cgcggagccg ccaacaattt
     7141 gggcgctaat gtcacttacg gcttcctggt gctgaatggc tccgacaatt cggtcatcgg
     7201 ctggagcacc aatacgggaa ctactgcagc agggattaat ctgacgttca gtttttcttc
     7261 cctggatggt tctcccctgc ttcttgacgc ggcattgaca taccgtttcc tggccgtgag
     7321 ccagtccgtg atggacttga tgcaggatac gtctaaaacg tatttatatg ctgcgggggg
     7381 aacagccgcc cctactgcta acacggaagg agataccgta acgatcagcg gcggattgac
     7441 tgctcccggc atccgcggcc attatgacgc cgagggagcg cctggtgatt ctgtcgttat
     7501 tacgggagcc aacggaacca atactttcag cttattatcc ccgattttca cggaaatccg
     7561 aggggaaatg gtgccggaac cagccacggt ttccctgggc ctgctgggac tggccgcgct
     7621 gatgatgcgc cgcctcaggg cttgagcttc ctgatggcga aaaatcggcg gatgagagct
     7681 gttcttgcgg aacagctctt gttttttata tccagagagg aagaattgct tatccgtatg
     7741 cgggattcat gccctccgga aggtacggaa tttccggggg cagggggccg tatccggttt
     7801 tttcggcatg gcggcaattt gctggaaacg tttttgagac gcagtaccgg aaagcttttt
     7861 ctttaccgga aaatgccgtc aaattcggca gcgcgctttt cgtccatatg gtacacggca
     7921 gctttcacat agtggccttt caggccggat agggaacccc tttgcagctc acagacctgg
     7981 agggccgccg catacatatt attcgccgtc ctattccccg gcgctggtat ttcggaagaa
     8041 cggcaatggg ccccatgccc agcacttcat attcttttcc atcgtctgcc ctgatgacgg
     8101 acgttgcatc aacgatgttt cccgacgatg cggctgccgt ggacggcgac tgcatccagc
     8161 tccgggatga aggacggact gacgcgcatg atatggagca ggtaatgttc atggcagccg
     8221 gggacgaaat agttccagaa cgcttctctc gtgacatgtt ccgtttcggc atggtctgag
     8281 gattgttccg ttcttaatgc aatggtcatg aaaggttgtt ctttacggct cccccttgga
     8341 gaaattccag aggcggtgca tcgtcataat gtccggaatg ttcatggggc gcaccacgcg
     8401 gaacccgatc atgcctccgt ccgtcaggta ccagatgctt ttagggtttt gaggatcctg
     8461 acggttccag gcgggggtgc tggcgcggcg cgcagcgctt ctcaggctgt ccgggtcgtc
     8521 ttcccacgaa ccgccgcgaa cgatgtgagg ggcgccgggg atgatgacca aggggtcttt
     8581 cgcgggcaag ccgctccgtt tgccgtaggc atccggaacg taagagtcca aaacccattc
     8641 cgccacattt ccgtgcatgt cccggagtcc ccacttattt ggttttttag agcctgtttt
     8701 ctggtagcgg tcattggagt tgttccagta ccaggcgtac tggtccagag aggcttcccc
     8761 gtttccgtaa gaataggcgc cgggggagcc ggcccggcag gcgtattccc attccgcctc
     8821 cgtgggcagg cggtagtaat gcccggtctg ggcgctcagc cattcgcaga atttgctggc
     8881 ggcgtggtgg gacatggaga tggcgggcag accgtgttca tagccgtggc ccatgcccag
     8941 gttcatggcg gtgtaggggg cggtaggctg cgtaacggag tcccacagtt cgtcatccgg
     9001 ctgttcctcc agaagctggc cgtccttggc gcgcggacgc ccgttttcca tgaaggccgt
     9061 ataaagttcc caggggattt ccgtttccga gatccagaag ggggagatgc tcactttatg
     9121 ctgcggacct tcgtccggtt tccggtgcgg ctcttccgcg ggactcccca tgaggaacgt
     9181 tcctcccggt atggcgacca tgcgcaggga agctcccgcc acgggaaccg tttccgtgta
     9241 ggattcaaaa cgtgccggat ttccggaagc ttcaatgagc tgatggattt ggcgcgttgt
     9301 gccgaccagc tcccgggacg gcaggtcatc cggaatggga agggcaggac cggcagcgcg
     9361 gtccagttcc cgtttttgca gcgcggatcg gctttctccc cactggcgtg cgctggtaat
     9421 gcgcgcggca tcttccgtgg ccgggcgggg ggaattattt tcttcccggc acccggccag
     9481 cagggcgctt cctcccagaa agcaggaaac aaggaaaatg ccgcgcatgg aatggagaaa
     9541 accggaatgc cctacatcgt catgcctccg tcgcaggcaa tgacctgccc ggtgatgtaa
     9601 cgggcatcgt cagaggcaag gaaggccgtc agggcggcga tatcttccac ggaaccttgt
     9661 tctttcaaag gtattttctt aacgatttct tccttgagat tgtcgggaat ggcattggac
     9721 atttccgtgg agatgaagcc gggagcaatg gcgttgcacg tgactttgcg cggagcgaat
     9781 tcctgagcca gtgatttggt gaaaccgatg aggcccgcct tggaagcggc gtaattggcc
     9841 tgaccgatgt tgccgacgag accgatgacg gagctcatgt tgatgatgcg cccggccggg
     9901 gatttcatga gaacgcgctg gagggccttg accgtattga acgcgctttt caggttggtg
     9961 tccagaacgg catcccagtc ttcctctttc atgcggagca tcagggagtc ccgcgtgatg
    10021 ccggcgttgt tcaccaggat gtcaatctgc gggaagtctt tcaaaatggc ggccatggtt
    10081 tcctgaacgg ccgcgtaatc cgctacgtcg caggggtagg ccttgcagga atccggaaat
    10141 tccttgttga tttcttctgc ggcccccccg cagctggatg gactgcggct gatcaggatg
    10201 accctggctc cttccgaagc gaagcggcgc gcgacggcat tgccgattcc gcggcccgcg
    10261 ccggtaacga tggctgtttt acctgctaac ttttgcatgc tgcccacagt aaacccgttt
    10321 ttcacggttc cggcaagctt gaaatggact tggccgcgca ggaacccata cggggaaggg
    10381 gcgtgccggg aatgaaaaaa gaggggggag aaacggggcg gggggctact gtccggcctc
    10441 ttcattttcc cggagtgcac cggggggcgc cccgtcttca tccggttcta ccaggtcgct
    10501 gaattcatcc gaattttcca aaatgtcctt taaggcggcg gaaccgtaat agcgggcctc
    10561 aaacaggcgt ttgccttcct gcctgcagcg gttgtccagc atttccattc gtttttccat
    10621 tttttctatc aaggcgtctt ctttctcctt ttccgcatcg ttcaatttat cctgaagctg
    10681 gaggaaatgc cggatgtcct tctgaatgtc ctgcagcgtt ttgacggcgt tgtccgcgct
    10741 ttccttgtcc tgaacgcctg ccaacgtctg ctggatattg atggcaaagg aaaaggcctg
    10801 gttgatcagg gattccgcgg aaggaatttt ttccgccgga gccgctgctg cgggggaagc
    10861 cgttccggcg gccgtttcac caaatgcaag agaggctccg gacagaagcg cagaatataa
    10921 gagaggaaca agaaaagcct tcatcctgtt cttttaaggc aggatgaaat ccacggcaag
    10981 gaaaaagggg aaactgaaaa aagagcctta ttccgccgtg atgccgcctt tttcatcgtc
    11041 cagaatgcct gacttttcca gatagtagtc atatccacct gcgtaggcgg tgatggtccc
    11101 ccggttcaca tgcagggttt tttgtgccag ggaacggatg aagtgcacat cgtgggagat
    11161 gaagaccagt gttccttcat aatgcttcag agcctgcacc agggcttcta cggacaaaag
    11221 gtccaggtgg gtggtcggct cgtccatcag caggaggttg ggcggatcca ccaggaattt
    11281 gaccaggctg agccgcgatt tttccccgcc ggaaagaacg ctgacgcgtt tttccacatc
    11341 cagcctccgg aacaggaagg aacccaggat ggaacgcgct tcttcctccc ggatttcagc
    11401 gctgcatttc atgatttcct ccagcacggt attttccgga ttcaggtttt ccgttcgcgc
    11461 ctgggagaag tagccgatgc gcgtcgtggt accgggagtg cgttgtccgg agtcaatggg
    11521 gatgatgccc gccaggattt tgagaagagt ggatttgccc gcgccgttcg ggcctacaag
    11581 aacagtgcgc tccccgcgtt ccaccagcag gtccaggttt tcataaaccc tgcggtcgcc
    11641 ataggattgg cagacttttt ccagctcaat gactttctgg gtgctgcgcg gaggctgggg
    11701 gaagttgaat ttaaatactt tcctgcgggc taccggtttt tgaatgattt tcatcttttc
    11761 cagctgcttg atgcggctct ggacttgccc ggctttggaa ttgatggagc ggaaacggtc
    11821 aataaattcc tgaatgtgcg ctatttcctt ctgctggttg cggtaggccg cctgaagctg
    11881 ctcgaagcgc acgtcctttt gttggaggaa gtccgagtaa ttgccgcggt attccaccag
    11941 ttcttcgttg tcgatgtcgt acacgctttc caccagctca tccatgaaat cccggtcgtg
    12001 ggaaatcatc aggatggctc cggggtagtt tttcaggtat cgctggagcc acagcaggga
    12061 caggaggtcc aggtggttgg taggttcgtc cagcatcagg aggtccggct ccaggacaag
    12121 gagcttggcc aggtacgcgc gcatgatcca gccgccggac atttcccggg cggggcgatg
    12181 gaagtcgctt tcccgaaagg ccagcccttt gagaattttc ttggctttgg gctccagctg
    12241 gtaaccgttg gcggcgttga aagtgtcaat ggcttccgcg tattccggcg tatccgtttt
    12301 gttggcgttt tccgccgtcc ggatggtgtg gatggcctgt tccatttccg gcgtgatgcc
    12361 cagggcgatt tccagaacgg tttcatcctt cggttcgctg gcttcctggg gaagatagcc
    12421 cacgatggcg tattcatcca tgctgatgga gccttcgtcc ggcgtgtctt ctcccagaat
    12481 catgcggaac agggtggatt tgcctgctcc gttggggcca accagagcca cccgttcccc
    12541 ccagttaatg gtcatttccg tttccctgaa caaggtccgt ccggcgtggg attttgtgag
    12601 atttttgatc gtcagcatgg tgaagagagg atgtattcta ccgggatgga aaggggaagg
    12661 caagagccgt cagggcggag gcaggcattt ttgaaagctt tactggattt ttacgcgtag
    12721 tctgctagcc ttggcgcgcc atgccgacca cgcagacatt caggcttttg cttgctgccg
    12781 cccttttgtg cggatggagt tcctgctgta ctcctccggc ggaggattat atacaacaaa
    12841 cttacgtgca gcagcaaatg tccgggctgg ctaatgcctt cctggcgctg ctgccgccgg
    12901 atcaggcctc tcttcccgct gccggagcgg aggccaggtg gctggcggaa acggccgtgg
    12961 tccagtccgc agcgattgcc cgggacaaca ggactgtgct gtttggctgg ctgaacaata
    13021 ttctggtcaa ttccaacctg cgcgacaggg ggctgtgctg gcaggtccag caggatttgt
    13081 accgggacct gcgccgccgc cccgtgaagt atttccgcat agggctgacg attcgagacc
    13141 gtggaacggg cagggagcac agttgcgtgt atgtcaatgc cgcggggaag ggattgcagg
    13201 gctccattgt tctggatgcc tggaagaact gcgggcatct ggtgacgctg acccagaagg
    13261 accgggaagg cggcaaatgg gaggaggact ggcgggaacc atttgtttcc aaggcctttc
    13321 cggagggcca ttcctacggc atggaacatc acctggtctg gcccgggtgg gccaggaaac
    13381 gccccattct ggttcagcgg atattccagt ccgatcagca gaatgaggcg aaggcggccg
    13441 ctgaataaag gggaagcctg atccggcagg aaccggcaca cggtgctgcg ccgcggcggt
    13501 ttgcggtatc cgccgttttt aaggaaaatc ccggcgaatc ggcaaatggc ggagggaatc
    13561 cggactcagg gcaaataaaa acgcactcag tgcgtacacc gagtgcggat taattggata
    13621 atttgctagt gttgcagggc aaaaccccgc tgcaaactta cttgcccttg gcctgcacaa
    13681 ccggagcggg agcaggagcg gtggtttgct gttgctgctg ctgctgggag caggaagcga
    13741 ccaggcaagc ggcgccggcg atggcgagga tagcgatgtt cttcataatt cgaattaaat
    13801 acagtgtttg ttaactactg gaacctccgc atccacggag gtttgctggc accaatgtaa
    13861 atggtggcaa gtagaaatca agagattttc ttgttccatg tcacggcatt acagaa
//
