LOCUS       c00006_gnlPro..        16331 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MGODJNPI_6.
ACCESSION   c00006_gnlPro..
VERSION     c00006_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 23:37:22
            Original ID  :: gnl|Prokka|MGODJNPI_6
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 61436
            Orig. end    :: 77767
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16331
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[71436:74429]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12993
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16331
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16331
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             75..1619
                     /locus_tag="ctg6_54"
                     /transl_table=11
                     /translation="MKKLSTSKQMAINMVAAIVSFLIGTGINFVLAPYLVKELGSETYG
                     FIGLANNFVQYATIVTSALNSMSGRFISIEYSKGNIDKASRYFSSVLVADLIIAGVLLL
                     VSSIITFNIEFILNVPENLVDSVKILFALTFATFIISVITAIFTTAAFVKNKLYINSLR
                     DIASNTLKLLLVVILFSFFPAKVYFLAMASLASGIFLLLTNIKVKNKILPEVKMNFNLF
                     SFKLVKVLISAGIWSSIGYLSTALNRGLDLLICNLTLGAGLMGLLSIANTVPHCIDNLI
                     TTIANIFTPRFTILYAKGNTDLLVEETKFSSKIMSFLMTAPLAGFIAFGNKFYTLWQPT
                     KSPDEITIIQILSVLVCISYLFTCHTRTLSSLFTVCNKLKASVLISLVCGVLTVIIVLL
                     LIHFTPLGVYAIAGVSSVFIGLKAIVFVPLYAAHILKIKLTTYYRSIFRGWFCFAVVIT
                     MFIFINSFVHANSWMSFLLLCAASGLAGYAVSVPLIFSRKELVLIKDKIKKKFKKS"
     CDS             1643..2557
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_55"
                     /sec_met_domain="Glycos_transf_2 (E-value: 4.4e-30,
                     bitscore: 96.8, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYTFSVFTPSYNRAKTLPRLYEALKRQTYRNFEWIIVDDGSAD
                     NTKETVEKFISDRPDFNITYKYQTNKGKHIATNVAAQIAKGEFFITIDSDDSVKDNALE
                     TFINEWNKIPDEDRSKYKGISCRTCNESGKTNGCPLPSERFDCSDLDLRLKYKIDGEMW
                     GMTKLEIIRANPYPCVSGLHFYPENIYWDNIGRKYITRFIDTPLRYYINDQENSLTGNA
                     YSAHRETIFVRLHFINECWDYAKSNPKFFIKQFVGLSRDGLLNGKRFSEIKKMPDTFSK
                     RALAVIFYPMGYFLYKKQSGGSR"
     CDS             2557..3636
                     /locus_tag="ctg6_56"
                     /transl_table=11
                     /translation="MKKVGIVTFHRALNYGAVLQSYALQKTVSSLGAECEIVDYICPKI
                     TADYKPFRIYKNDLLKSFAKSCVMVRRRAKRRDAFKSFFNNYLVKSKKSYTPQNIGELK
                     NDYDLFISGSDQVWSPRCVGFDPAYFLTFADDRQKYSYAASFAVPTLPDEFIDEYKKRL
                     NGFQKFSVREPSGEKLVKELTGRTAETHLDPTLLISADEWKKIAVSKIDKPYILIFTAN
                     PAVSLVDFALKLSKEKNLPVYCINDAPHPVSHGINYIVAPTVEEFVGCFKNAEYVVTNS
                     FHGTAFSVIFNKNLFVEFKNKSGRNIRSEGLLKSLGIDREIVDGNCNETEINWDIINAQ
                     LKTLGSKSKKYLSEIVNME"
     CDS             3640..4767
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_57"
                     /sec_met_domain="Fer4_7 (E-value: 6.9e-09, bitscore: 28.4,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0027, bitscore: 10.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIFSNKNQCCGCTACKSICPKNAISMQVDNEGFLYPIINKELCI
                     NCGLCKKVCAFQNGYTRNSVVNAYAVKHHDIKTRLSSRSGGAFIPISDYIIQNNGTVYG
                     AAFNEDFSVSHIRAESCTERDRMKGSKYVQSELGNTFLNVQNDLKDNRYVMFSGTACQV
                     AGLNNFLEKSKTKTDKLFTVDLVCHGVPSNKIWTDYLDYINNKHKGNKITDVNFRDKSL
                     GWDVHFESFCIDGKKYYSKDYAAMFYQNDILRPSCYECKYTNLFRPADFTLADFWGIDN
                     QINNFNDNKGVSLFIINSQKAQKLFELVKNQVEYIKVDINKCTKANPNLRRVTPKPDNR
                     EDFWKKYHEKGFSKTFPSYKRKIIFSKIKHKLFRR"
     CDS             4774..5970
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_58"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 4.2e-36,
                     bitscore: 116.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 1.2e-28, bitscore:
                     91.4, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTESYKVAIAGTGYVGLSNAVLLSQKHEVTAVDVVESKVRLINEK
                     KSPIADREIEEYLADKKLNLVATVDAKSAYKNADFVIISTPTNYDDERHFFDTSSVEAV
                     IELVIECNPNAVIVIKSTIPVGYTKSVIEKYKYTKILFSPEFLREGKALYDNLYPSRII
                     VGVDMANEELKKSAETFATALADCAIKENIDTLFMDYTEAEAVKLFANTYLAMRVSFFN
                     ELDTYAEMKNLNTKSIIDGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLKANFSDVPND
                     IISAVVTSNKTRKEFITSQIMNKNPKAVGIYRLTMKSNSDNFRQSSIQSVMELLKNNGI
                     ELIIYEPTLKVDLFEGFSVENDFEKFVTKSDVIVANRYSSVLDCVKEKVYTRDLFFRD"
     CDS             5986..7137
                     /locus_tag="ctg6_59"
                     /transl_table=11
                     /translation="METLIIGKPKIEKLDNRARLCSKISENGKPSYTLWFDVDAKYADY
                     LTESADAFVVALLPYAMNNSLNISAEAKMSKQLCFQLNEIFIPVLTKNSKLFNKISISA
                     KELTQENYCCKNASATGFSRGVDSFDTICSLSENSMEKLSHLTFFNVGSHRSTANYTPE
                     QSAELYENRLEIAKKSAKIFDMPLIDINSNLGEHLTLPYVKVHHYCSFSAVLCMQKFFK
                     NYYYASGYPISSFSIKQCDTGSAHYEAFTASMLSTESTDFYITGLEKTRLEKVDFISKF
                     PITYDNLNVCYYGENNCGHCEKCVRTQFELMALGKLELYKNVFDIPKFYRDKNKYMDYV
                     LKHQNKDYYTEILSLMKKKGFKLTPIQKIKKAVYAVYLKFRGN"
     CDS             complement(7448..7666)
                     /locus_tag="ctg6_60"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEEAAKEEPQAEVTADELAEEE"
     CDS             complement(7799..9652)
                     /locus_tag="ctg6_61"
                     /transl_table=11
                     /translation="MKSENIKKFGCVLLSAIMLSGISVCAVSAEEKSTEIHIVHTNDIH
                     GYYKSTSGGQIGFDAVKTIADKENADLILDAGDTFHGQSFATVEEGKSIAELMDAVGYD
                     AMTPGNHDWSYSADRLRELDRESSFTILASNVADTNGDRYFDNNFYIKNVTADDGTKVR
                     VGVFGVIDEDFYTSTSAKNVENVRFENSAETATAYANFLRDDENCDIILALTHNANPEK
                     FIAETSGIDAVIAGHQHILIDKYCTDSDGKSVKLVEANCFFKNVGVLTLTYSNEKGVTD
                     AVEKTYSSADTKRMSDEKIASDISAIEKREQSVLSEVIGESSRDYAYSWEELRTSEQEI
                     GRIVTAAYLDFTGADVAMENAGGIRSGIPKGNVTYSDLISISPYGNVLVEKELTGQQII
                     DILEFSVDLMKKNNAVYDLQKQAIKDGEDPYQYSWPDNSGSVMQFSGLSAVYDYSKPCG
                     GRVSDVKIGGKAIDTLKTYRVVSNNYAFDSSDYGDVASLTTVKEYTTCEQILRDYIGKG
                     DFEKAAANANLVEKSSPSEEPIATQEQTVQTAPTGEPATVGTTSANPTSATGGAATSDS
                     TPSQPDKNGSVQTGVTATAVMMLVVISGGVLFALAERKKRI"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.2;
                     E-value: 1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_62"
                     /sec_met_domain="Radical_SAM (E-value: 4.8e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNAVKGFVHSIETFGSVDGPGVRFVIFLSGCAMRCQFCHNPDT
                     WKHDENTVEYTADELLNKALAYRPYWKNKGGITVSGGEPLLQIDFLLDLFKKAKKQGVN
                     TCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDIKHIDNEQHKILTGQPNTNILEMARQ
                     LSDMGKPVWIRHVLVPERNDKDEYLFRLADFIRSLRNVERVEVLPYHTLGVYKWKALGY
                     DYPLEGIDPPSKERVKNAEMILNGEKTRD"
     CDS             complement(10756..12993)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_63"
                     /sec_met_domain="Gly_radical (E-value: 6.9e-41, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 3.5e-271, bitscore:
                     892.9, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQRNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDEDGVAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             complement(13260..13751)
                     /locus_tag="ctg6_64"
                     /transl_table=11
                     /translation="MKTDKVITAMIEYFGSDKKRIHHFLKVYSFAKTIGESENLLPDDQ
                     ELLEISAIVHDIGIKVSEEKYNSSAGKYQELEGPHEAEKLLAALGYEKTFIDKVCYLVG
                     HHHTYGNIDTLPYRILVEADFLVNLYEDDSSRSAAEQAYDKIFRTNTGKNLLKIMFLIP
                     "
     CDS             complement(13955..14491)
                     /locus_tag="ctg6_65"
                     /transl_table=11
                     /translation="MVIIMAHPIKHFRTITRHRHKVIANCARAGILRQGLIHDLSKYSP
                     TEFILGAKYFQGTRSPNEKERELYGYSQAWMHHKGRNRHHYEYWNDYNPKTKQIENVEM
                     PVKYVIEMFCDRVAASKIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRD
                     EGEEKTFAYIRSMKK"
     CDS             14656..15843
                     /locus_tag="ctg6_66"
                     /transl_table=11
                     /translation="MKKKIFILLLCVVLIATCILCGVTGIFGNDSQNSPKPQTPDTAAT
                     ENMTFPSKVDSLTLKVGESKLIELSSEKAKSVTKWTSSDSKIVTVDDGGRVDALKEGTA
                     LISAISKDKSKSEFQVTVAKSTTKKQQSYSTCITANLDKLENNKRNTAKNLYAIKVNRT
                     ANCVTVYTYDEKGKYTIPVRAMICSTGLDNSTITGDYTIGIKSEWLSLVGDVFGRYISG
                     ISGDYLFHSVPYYSMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWVYDNCPAGTNVSI
                     YDDAENAGPLGKPDAIKITDFTNKWDPTDSNKKCSYAKATPIISGANDYTIKSGGEFYA
                     LAGVTAVDTCGNDITSNIEVFGNVITTRKGKYKVTYSVTDVLKRTSSVTITVTVQ"
ORIGIN
        1 gttgttgaac tgaagaaaga acagctcttc aatgcttttc caaaatttta atcagttaaa
       61 actaaggtca tattatgaaa aaattatcaa caagtaaaca aatggcaata aatatggttg
      121 ccgccatagt gtcttttttg ataggaacag gaattaactt tgttcttgca ccctatcttg
      181 taaaggaact cggttctgaa acctacggat ttatcggact tgcaaacaac tttgtccagt
      241 atgccaccat tgtaacatct gctctcaact caatgtcggg cagatttatt tcaattgaat
      301 acagcaaagg aaacattgac aaggcgtcaa gatatttcag ctcggttttg gttgccgacc
      361 tgattattgc cggcgtttta cttttggttt cgtcaattat tacattcaac attgaattta
      421 tactgaatgt tcccgaaaat cttgttgaca gcgtaaagat attgtttgcg ctcacttttg
      481 caacatttat aatcagcgtt atcacggcaa tatttactac tgcggcattt gtaaaaaaca
      541 agctgtatat caattccctc cgtgatattg cgtcaaacac gctcaagctc ttgcttgtag
      601 taattttgtt ctcgtttttt cccgcaaaag tatattttct cgctatggcg tcacttgcaa
      661 gcggaatttt tcttttgctt accaatatca aagtcaagaa taaaattctg ccggaagtaa
      721 aaatgaactt caaccttttc agtttcaagc tggtaaaagt tcttatttcc gcaggaattt
      781 ggtcgtcaat cggttatctc agcacagctc tgaacagagg tcttgacctg ttaatctgta
      841 acctgactct cggagcggga ctcatgggac ttttgtcgat tgcaaacacc gttccgcact
      901 gcattgataa ccttattaca accattgcaa atatcttcac tcccagattt acaatccttt
      961 atgcaaaggg caacacggac ttacttgttg aagaaacaaa gttttcgtca aagattatga
     1021 gttttctcat gactgcacct cttgcgggat ttattgcgtt tggcaacaag ttctatacat
     1081 tgtggcagcc gaccaaatct ccggacgaaa ttaccataat tcagattttg tcggtgcttg
     1141 tatgtatttc atacctattt acctgtcaca caagaactct ttctagcctt ttcaccgtat
     1201 gcaacaagct caaggcctcc gttcttatct cgcttgtgtg cggtgttctt acggttatta
     1261 tcgttttact gctcatacac tttacaccgc tcggcgttta tgctattgca ggcgtcagct
     1321 ctgtttttat cggtcttaaa gcgatagtat ttgttccgtt atacgccgca catattttga
     1381 aaataaagct tacaacatat tacaggtcta ttttcagagg atggttctgc tttgctgttg
     1441 ttatcaccat gttcatcttt atcaacagct ttgtacacgc aaacagctgg atgtcattcc
     1501 ttcttctctg tgcagcaagc ggactggcag gatatgccgt ttccgttccg ctcattttct
     1561 caagaaaaga actcgttctt atcaaggata aaattaagaa gaagtttaag aaaagctaaa
     1621 ttattatcat tttgaggttg caatgactga atatactttt tccgttttta caccgtcata
     1681 taacagggca aaaactctgc ccagattata tgaggcgctg aaaagacaga catacagaaa
     1741 ttttgaatgg ataattgttg atgacggttc agccgacaac acaaaagaaa cggttgagaa
     1801 attcatcagc gacagacctg actttaacat aacctataaa tatcagacca acaaaggaaa
     1861 acacattgca acaaatgttg cggcacagat tgcaaagggt gaattcttta taacgattga
     1921 ctccgatgac agcgtaaaag acaacgccct tgaaacattt ataaacgaat ggaataaaat
     1981 tcccgatgaa gacaggtcaa aatacaaggg aatttcgtgc cgcacctgta acgaaagcgg
     2041 caaaacaaac ggttgtcctc tgccgtcaga acgatttgac tgttccgacc ttgacctgag
     2101 attgaagtat aaaattgacg gtgagatgtg gggaatgaca aaacttgaaa taatcagagc
     2161 caacccctat ccgtgtgttt cgggacttca tttttatccc gaaaatatct attgggacaa
     2221 tatcggaaga aagtatataa cccgttttat tgacacaccg ttgcgatatt acataaacga
     2281 tcaggaaaat tctttgacgg gtaacgctta ctcggctcac agggaaacta ttttcgtaag
     2341 actccacttt ataaacgaat gttgggatta cgcaaagagc aatcctaagt tctttatcaa
     2401 acaatttgtg ggactttccc gtgacggctt actcaacggc aaaagatttt ccgaaataaa
     2461 aaagatgccc gacacatttt caaagagggc tcttgcggtc atattttatc ccatgggata
     2521 ttttttgtac aaaaaacaat cagggggaag cagataatga aaaaggtagg cattgtaaca
     2581 tttcaccgtg cattgaacta cggcgctgtg cttcagagct atgcgttgca aaaaaccgtt
     2641 tcctcgctcg gcgcagagtg tgaaattgtt gactatatct gtccgaaaat cacagccgac
     2701 tacaaaccct ttcgcattta taaaaacgac cttctgaaat cctttgcaaa aagctgtgtc
     2761 atggtaagaa gaagagcaaa acgcagagac gcttttaagt cgtttttcaa taactatctt
     2821 gtaaagagta aaaagtcgta tactccgcag aatatcggag agcttaaaaa cgattatgac
     2881 ttgttcattt cgggaagcga tcaggtgtgg agtccgagat gcgtcggctt tgatcccgct
     2941 tattttctga catttgccga tgacagacag aagtattcat atgcggcaag ctttgccgtt
     3001 ccgacattgc ccgatgaatt tattgatgaa tataaaaaaa ggctgaacgg ttttcagaag
     3061 ttctcagttc gtgaaccgag cggagaaaag cttgtaaaag aactcacggg cagaaccgcc
     3121 gaaactcatc ttgatcctac cctgctgatt tcggcagacg aatggaaaaa gattgccgtt
     3181 tcaaaaatcg acaaaccgta tatcctcatt ttcacggcta atccggcagt ttcgcttgtg
     3241 gattttgccc ttaaactgtc aaaagaaaag aaccttcccg tttactgcat aaacgatgca
     3301 cctcaccctg taagtcacgg tataaattat attgttgcac ctactgttga ggaatttgtc
     3361 ggctgtttca aaaatgccga atatgttgtt acaaactcgt ttcacggaac agcgttttct
     3421 gttattttca acaagaatct ttttgttgaa ttcaagaaca aaagcggaag aaacatccgc
     3481 tccgaaggtc ttttgaaaag tcttggaatc gaccgtgaaa ttgttgacgg aaactgcaat
     3541 gaaacagaaa taaactggga tataattaac gcacaattaa aaactctggg tagtaaatcc
     3601 aagaagtatc tttctgaaat tgttaatatg gagtaacaaa tggagatttt ttcaaataaa
     3661 aatcaatgtt gcgggtgcac tgcctgcaaa agtatatgcc caaagaatgc aatttcaatg
     3721 caggtagaca acgaaggatt tttgtatcct attattaaca aggaactttg tattaattgc
     3781 ggtctatgca aaaaggtttg tgcttttcaa aatggctata cacgaaacag tgttgtcaat
     3841 gcttatgcag ttaaacacca tgacattaaa actaggcttt caagcagaag cggcggtgca
     3901 ttcattccca tatctgacta tattattcag aataacggta cagtttatgg tgccgcgttt
     3961 aatgaagatt tttcggttag tcatattaga gctgaaagtt gtactgaaag agatagaatg
     4021 aaaggctcaa aatatgttca aagtgagctt ggcaacacat ttttaaatgt ccaaaatgac
     4081 cttaaagaca acagatatgt tatgttttca ggaacagcat gtcaggttgc aggtctcaat
     4141 aactttcttg aaaaatctaa aacaaagact gacaaactgt ttacagttga tttagtatgt
     4201 cacggtgttc caagcaataa aatttggaca gactaccttg attatataaa taataagcat
     4261 aaaggaaata aaattacaga cgtaaatttc cgagataaat ctctcggctg ggatgtacat
     4321 tttgaaagtt tctgtattga cggcaaaaaa tattattcaa aggattatgc cgcaatgttc
     4381 tatcaaaatg atatacttcg cccatcttgt tatgagtgca aatatactaa tctgtttaga
     4441 cctgctgatt ttacacttgc cgacttttgg ggaattgaca atcaaattaa taatttcaat
     4501 gataacaaag gcgtttcgct ttttattata aactcacaaa aggctcaaaa attgtttgaa
     4561 cttgtgaaga atcaggttga atatatcaaa gttgatataa ataaatgcac caaagcaaat
     4621 ccaaatctta gaagggtaac tccaaaacct gataatcgtg aagatttttg gaaaaaatac
     4681 catgaaaaag gattttcaaa aacatttccg tcatataaaa gaaaaattat ctttagcaag
     4741 ataaaacata aattattcag gagataaaac ataatgactg aatcttataa agtagcaatt
     4801 gccgggacag ggtatgtagg tctttcaaac gctgtacttc tttcgcagaa acacgaagtt
     4861 accgctgttg atgtcgttga aagcaaagta aggttaatca atgaaaagaa atctccgatt
     4921 gccgacaggg aaatcgaaga atatcttgct gacaaaaaat taaatttggt tgcaaccgtc
     4981 gatgcaaaat ctgcgtacaa aaatgctgat tttgtaatta tctctactcc taccaattac
     5041 gatgacgaaa gacacttttt tgatacatcg tccgttgagg ctgtaattga gcttgtaatt
     5101 gaatgcaacc caaatgcggt tatagttatc aaatccacta taccggttgg atacacaaaa
     5161 agtgttattg aaaaatacaa atacacaaaa attcttttca gtcccgaatt tttgcgtgag
     5221 ggcaaggctc tctatgataa cctctatccg tcaagaatca ttgtcggtgt tgatatggca
     5281 aatgaagaac tgaaaaaatc tgccgagact tttgcaacgg cacttgcaga ctgtgcaatt
     5341 aaggaaaaca tagacactct ctttatggac tacacagagg cagaagcggt aaagcttttt
     5401 gcaaatacat accttgcaat gcgtgtcagc tttttcaacg agcttgacac atatgccgaa
     5461 atgaagaacc ttaacactaa aagtatcatt gacggtgtgt gtcttgatcc gagaatcgga
     5521 aatcactaca acaatccgtc ctttggctac ggcggttact gtctgccaaa ggacacaaaa
     5581 cagctcaagg ccaatttttc ggatgttccg aacgacataa tcagcgctgt tgtaacatct
     5641 aacaagacaa gaaaagaatt tattacatca cagataatga ataaaaatcc aaaagctgtc
     5701 ggaatttacc gccttacaat gaagtcaaat tccgataact tcagacaaag ctcaattcag
     5761 agcgttatgg agcttttgaa aaataacggt atcgagttaa ttatctacga accgacactt
     5821 aaagtcgatt tattcgaggg ctttagcgtt gaaaacgact ttgaaaagtt cgtcacaaaa
     5881 tcggatgtaa tcgttgcaaa cagatacagc tccgtccttg actgtgtaaa agaaaaggtt
     5941 tacacaagag atttgttttt cagagattaa tttgagggta aaagtatgga aacattgatt
     6001 atcggcaaac cgaaaattga aaaacttgat aatcgtgcca gactctgttc aaaaatcagc
     6061 gaaaacggaa agccttccta cactctctgg tttgatgttg atgcaaagta tgctgactat
     6121 ctgaccgaaa gtgccgacgc attcgttgtt gcgctgttgc cgtatgcaat gaacaacagt
     6181 ctgaatattt cggcagaagc aaagatgtcg aagcaactgt gttttcagct taatgaaatt
     6241 ttcattcccg ttcttacaaa aaattcaaaa ttattcaaca aaatttcgat atctgcaaaa
     6301 gagcttacac aggaaaacta ctgctgcaaa aatgcgtcgg caacaggatt ttcgagaggt
     6361 gtggattcat ttgacacaat ttgcagtctt tccgaaaaca gcatggaaaa gctgagtcat
     6421 cttacctttt tcaatgtcgg ctcccacagg agtacggcta attacacacc cgaacaatct
     6481 gccgagctgt acgaaaatcg tcttgaaatt gcaaaaaaat ccgcaaaaat ctttgatatg
     6541 ccgttgattg acattaattc aaatctcggt gaacatctta ccctgccgta tgtaaaggtt
     6601 catcattatt gcagcttttc ggcggtcttg tgtatgcaga aatttttcaa aaactattac
     6661 tatgcgtcgg gatacccgat aagcagtttt tcgataaaac aatgcgacac cggctcggca
     6721 cactatgagg catttacggc aagtatgctg agtaccgaaa gtaccgattt ttacattaca
     6781 gggcttgaaa agactaggct tgaaaaggtt gacttcattt caaaatttcc gattacatat
     6841 gataacctca atgtgtgtta ctacggtgag aacaactgcg gtcactgtga aaagtgcgtc
     6901 agaacgcaat ttgagcttat ggcactcgga aaacttgaac tgtataagaa tgtttttgat
     6961 attccgaaat tttacagaga caagaacaaa tatatggact atgttctcaa acatcagaac
     7021 aaggactatt atacagaaat tctcagtctt atgaaaaaga agggtttcaa gcttacgcca
     7081 attcaaaaaa ttaaaaaggc tgtctatgcc gtttatctta aattcagagg gaattaaggc
     7141 ttacggttgc tttaaccgac aagccattga ggaggtatag cagatatcag atgatgtctg
     7201 cgtttttata atgcctcacg gctgtgggtt tggcggttac ttcgcacaaa acaaaaatgc
     7261 atcagagctt ttcgggcaac tgatgcattt tcttttttaa actgttttct tgaatagact
     7321 gcggtggcac accgccgaca tcattttctg ttttcaactt tcaattctta attgaaagca
     7381 ccgctctggt atttaacttt tgcgtatgca aatactgcta cccgaattgg gtgcaacaac
     7441 ttgttgctta ttcttcctca gcaagctcat cggctgtaac ttctgcctgc ggttcttcct
     7501 ttgcagcctc ctcaggctct ttttcggaaa caatatcgtc aatttcctca ataagcttct
     7561 gttctgcgca tctgtgcttt tttaaagcga gaaatgctgc tgtggcagcc gcaagtgcag
     7621 agattgcacc gatgattgtg tagaataatt ttttgttttt atccattccg gcacctcttt
     7681 cagtattaat ataaatcagc ggaaaaaccg tatttttcta cttatcgcta ttttatacca
     7741 tttttacaaa tttttcaata ggcaactgat aatctttgca caaatggctg tcaatgtgtc
     7801 atattctctt tttacgctct gcaagggcaa aaagcactcc gcccgaaatt acaacaagca
     7861 tcataacagc cgttgctgtc actcctgtct gaacactgcc gtttttatca ggctgtgaag
     7921 gagtgctgtc cgatgttgcg gcaccgcctg ttgccgaagt cggatttgca gaggttgtac
     7981 cgacagttgc aggctcaccc gttggagcag tctgaacagt ctgttcctga gtagcaatcg
     8041 gttcttccga cggtgacgat ttctcaacaa gatttgcatt tgcggcagcc ttttcaaaat
     8101 cgcccttgcc gatataatca cgcagaattt gttcgcaggt ggtatattct ttcacggtcg
     8161 tgagcgacgc aacatcgccg taatcggaac tgtcaaacgc atagttattt gaaaccactc
     8221 tgtaagtttt taaagtgtca attgcttttc cgccgatttt tacatctgac actctgccgc
     8281 cgcacggctt tgaatagtca tataccgcac ttaaaccgct gaactgcatt acagaaccgc
     8341 tgttatccgg ccagctgtac tgatacgggt cttccccgtc ctttatcgcc tgcttttgaa
     8401 ggtcataaac cgcattgttt ttcttcataa ggtcaactga aaattcaaga atatcaatga
     8461 tctgctgacc tgtaagctcc ttttcaacaa gcacattgcc gtagggtgaa attgaaatca
     8521 aatcggaata tgtcacatta ccctttggaa tacccgaacg gattccgcct gcattctcca
     8581 ttgcaacatc agcacccgta aagtcaagat aagcggctgt tacgattctg cctatctcct
     8641 gctcgcttgt tctcagctct tcccagctgt aagcgtaatc cctactgctc tcgccgatta
     8701 cttcgctgag tacgctctgt tcacgctttt caattgcaga aatatcggac gcaatctttt
     8761 catcggacat tctcttagta tcggcagacg aatatgtttt ttcgactgca tcggtaacgc
     8821 ccttttcatt ggaatatgtc agagtaagca cacctacatt tttgaaaaag cagtttgcct
     8881 caacaagctt tacactcttg ccgtcactgt cagtacagta tttgtcaatg agaatgtgct
     8941 gatgacctgc gattaccgca tcaatgcccg atgtttcggc aatgaatttt tcggggtttg
     9001 cattatgagt cagcgcaagt ataatatcac aattctcgtc atctctgaga aaattcgcgt
     9061 acgctgtcgc tgtttcggct gaattttcaa agcgaacatt ttcaacattc tttgccgatg
     9121 ttgatgtgta aaaatcttcg tcaataacgc cgaaaactcc gactcttacc tttgtgccgt
     9181 catcagcagt aacattcttt atataaaagt tgttgtcaaa atatctgtcg ccgtttgtgt
     9241 ctgccacatt tgaggcaagt atggtaaaag agctttctct gtcaagctct ctcagcctgt
     9301 cggcactgta tgaccaatcg tgattgccgg gtgtcattgc gtcataacct acagcgtcca
     9361 taagctcagc aatgcttttt ccctcttcaa cggtggcaaa tgactgtccg tgaaaggtgt
     9421 cgcctgcatc aagtatcaaa tcggcatttt ctttgtccgc aatggtcttg actgcgtcaa
     9481 aaccgatttg accgcccgat gtggacttgt agtagccgtg aatatcgttt gtatgaacta
     9541 tatgaatttc cgttgatttt tcttcggcag atacagcaca caccgaaata cccgaaagca
     9601 ttatggcact aagcaaaaca caaccgaatt tttttatgtt ttctgatttc attactttac
     9661 tccttgcaaa ttaaaaatat gtagtaattg tttgtaaaat caatgctttg ttgggtgaat
     9721 tgtaccatat tctgcgcaat ttttcaatag ttttatattg gatacggtgg caagctgttt
     9781 tattattgca aaattctgct ttatctgcta ttattctaag atgttgataa cccaaaagtt
     9841 acgctgagat ttctcaacaa ggacagctta aaaatctttg aatacacctt tgattcatca
     9901 attttgctga agaaaaaaca acaaaagcag aataacaaat aaaaatcaaa acaaaaacgg
     9961 cagtaccaaa aaatcggtac tgccgttgtt atataagaaa ttaatctctt gttttttcgc
    10021 cgttaagaat catttctgca ttcttaacac gctcttttga cggtgggtca atgccctcca
    10081 aaggatagtc ataaccgaga gccttccact tgtacacacc gagtgtgtga tacggaagaa
    10141 cttcaactct ttcaacattc ctgagcgaac ggataaagtc ggcaagtctg aaaagatact
    10201 cgtccttatc atttctttca ggcacaagaa catgtcttat ccatacgggc ttgcccatat
    10261 cggaaagctg tcttgccatt tcaagaatat tggtgtttgg ctgtcctgta aggattttgt
    10321 gctgttcgtt gtcgatatgc tttatatcaa gcaacagcaa atccgtatat tccattagct
    10381 ctttccactt tgaatagaac ggctctttgg ttgtaaacgg gttggcgctt gtgtcaatac
    10441 aggtattaac gccttgcttt ttagccttct tgaacaaatc aagcaaaaag tcaatctgta
    10501 aaagcggctc acctccgctt actgtgatac cgcccttatt tttccaatag gggcggtatg
    10561 caagtgcttt attaagcaac tcgtcggcgg tgtattccac ggtgttttca tcgtgtttcc
    10621 aggtgtcggg attgtggcag aactggcaac gcattgcgca accgctcaga aaaatcacaa
    10681 atctcacgcc cggaccgtca acagagccaa aagtttctat tgagtgtaca aagcctttaa
    10741 cagcgttgtc cgacattaca ttctgtcgtg gcaggttctg gcaataacat ccagctgctg
    10801 ctctcttgta aggtcgatga acttaacagc ataacccgat acacggattg tgaagttagc
    10861 gtactcttcc ttctcaggat gctccatagc gtcaatgagt ttttctgtac cgaatacatt
    10921 tacattgagg tggtgtgcgc cctgatcaaa gtagccgtcc ataacattta cgaggttgtc
    10981 aacacgctcg tcatcgttgt gtccgagagc acccgggttg attgtctgag tatttgaaat
    11041 accgtcaaga gcgtactcgt aaggaagctt agcaacagag ttaagtgaag caagaagacc
    11101 gttctgctct gcaccgtagc ttgggttagc acccggtgaa agcggctcgc ctgcttttct
    11161 gccgtcagga agtgaacctg tagccttacc gtaaacaaca tttgatgtga ttgtaaggat
    11221 agaagttgta ggctctgaat ctctgtatgt gtggcaatac ttgagcttag ccatgaatgt
    11281 cttgagaaga tcaacggcaa tcttatctgc tctctcgtca ttgttaccgt atcttgggaa
    11341 gtcgccctct gtttcaaagt caacagcaac gccgtcctcg tcacggataa ccttaacctt
    11401 agcgtactta atagcgctga gtgagtcaac aacatgtgag aagcctgcaa tacctgttgc
    11461 aaatgttctt cttacatctg tatcgataag agccatttct gctgcctcat agtagtactt
    11521 atcatgcatg tagtgaatca tgttaagtgt gcctacatag aggtgagcaa gccaatccat
    11581 cattgtgtca tacttcttga taacttcgtc ataatcaagg tactctgatg tgataggtgt
    11641 atattcagga ccaacctgca tctttgtctt ttcatcaata ccgccgttga tagcgtagag
    11701 aaggcactta gcaaggttag ctcttgcgcc gaagaactgg atttccttac ctgtctgtgt
    11761 tgcggatacg cagcagcaga ttgagtaatc atcgccccat acaggacgca ttacatcatc
    11821 gttctcgtac tgaattgagc ttgttgtaac tgaaatatga gcagcatact tcttgaagtt
    11881 ctccggaagt cttgaagaat aaagaactgt gaggtttggc tcaggtgaag gtcccatatt
    11941 ctcaagtgtg tggaggaaac ggtagtcgtt ctttgtaacc attgaacggc cgtcaatgcc
    12001 aagacctgca acttcgagtg tagcccatac agggtcgccc gagaagagct ggttgtaaga
    12061 ctcaattctt gcaaacttaa ccatacggca cttcataaca aagtggtcaa cgagttcctg
    12121 agcctgtgat tctgtaagtg taccgttctc aaggtcacgc tcgatgtaga tgtcgaggaa
    12181 tgttgataca cgaccaacgc tcattgcagc gccgttctga gtcttgatag cagcaagata
    12241 accgaagtag agccactgaa ctgcctctgc agcgttctta gcaggctgtg aaatatcaaa
    12301 gccgtaagaa agtgccattt ccttcatatc gttaagagca cgaatctgat cagcgatttc
    12361 ttcacgaagc tggaagtcgc ctcttctcat accctgacgg tttgtttctg caaagtcctc
    12421 tttcttgcct tcgataagac ggtcaatacc gtaaagagca actcttctgt agtcaccgac
    12481 gattctgcct ctgccgtatg tgtcgggaag acctgtaaga atcttgttgt gacgggcaag
    12541 cttcatctcg ggagtataga tatcgaatac accctggttg tgagtcttgt gatattttgt
    12601 aaagatttcg tggagtttag ggcttggagt gtagccatac atctggcatg actgctcagc
    12661 cattttgata ccgccgtaag gcataaatgc acgcttgaga ggcttgtctg tctgaagacc
    12721 tacaaccttt tcaaggtctt tatcaagata tgcagcgccg taagctgtga tgccgcttac
    12781 aacctcagtt tccatatcaa gaacgccgcc cttggctctt tcttccttct ggagttcctt
    12841 gagctcgccc cagagcttgt ctgtagcttc tgtaggacct tcaaggaaag actggtcgcc
    12901 gtcataaggt gtgtagtttc tctgaatgaa gtctctgaca tcaatgtcgg actcccattt
    12961 gccacctgca aaatttgtcc attcttctct cattactgta aaacctccga taatgataat
    13021 taatactgaa ttttgtatat gacacaaaaa aatgccgact caattccaag cagacgcccg
    13081 gtaaggtcag ctccttgaaa aaatcgtcat acatccttgt attctgtcat ttattcactt
    13141 ttataatcat ataaccaaca ccattaaaat aacacttttt aagggcgttg tcaagcattt
    13201 tgagatactt tttacaccac tttttcacac tcaaaatact atggtaaatg agtacaattt
    13261 tagggtatga ggaacattat tttcagcaga ttttttcctg tatttgtgcg gaatattttg
    13321 tcatatgcct gctctgctgc actgcggctt gaatcgtcct cataaaggtt cacaaggaag
    13381 tctgcctcta ccaaaattcg gtacggcaaa gtatcaatat ttccataggt gtgatggtgt
    13441 cccacaaggt aacaaacttt gtcaataaat gttttttcgt aaccgagagc ggcaagcaac
    13501 ttttcagcct cgtgaggacc ttcaagttcc tgatactttc ctgcagacga attgtacttt
    13561 tcttcgctca cctttatgcc gatgtcgtga acgattgcgg agatttcaag aagctcctga
    13621 tcgtcgggca aaagattttc actttcaccg attgtctttg cgaatgaata aaccttgaga
    13681 aaatggtgaa ttcttttctt gtcacttcca aaatattcaa tcatagcagt tataactttg
    13741 tcggttttca tattatcact ccttacggcg agccgccgta ccctattcgt gtagacagtt
    13801 ttttgtttgt gcaattctgt aggggtagcc ttgcgaccgc cgcctgtggc ggataaaggg
    13861 agcaaagcgc tgtctgaaat aacgagcaat aggaagcaca tttatgtgca acgcattgcg
    13921 actatatttc agacgggagg attcgcacaa acaatcactt tttcatactt cttatatatg
    13981 caaaggtctt ttcttcaccc tcatctctca gcataaccaa taatttttca agcaaggcct
    14041 cggtgttggg gtgcatacgg tgtttgcctc tgattctgca aaaatatgta aacggagcgc
    14101 cgtccgtgta atttttgccg ttgtagattt tgcttgcggc aactcggtcg cagaacattt
    14161 cgataacata ttttacaggc atttcaacat tttcaatctg ctttgtcttt gggttgtaat
    14221 cgttccagta ttcgtaatgg tgacggtttc tgcccttgtg atgcatccac gcctgtgaat
    14281 agccgtacag ttctctttcc ttttcattgg gacttctcgt gccctggaaa tactttgcac
    14341 ccagaataaa ttctgtaggc gaatactttg acaaatcgtg tattaatccc tgtctgagaa
    14401 ttcccgccct tgcacagttg gcaattacct tgtgcctatg acgggttatt gttctgaaat
    14461 gtttaatcgg atgtgccata attatcacca taaattgtta gtttggaaaa tacaaaacat
    14521 tctccgactg acattttacc acatttctcg ccgatttaaa atagcacttg caagattgtc
    14581 gaaaaaaagt tataatatac aaaggttaaa attttgtaac catttaatgt taaattctat
    14641 aaggataggt aatctatgaa aaagaaaatt ttcattcttt tactttgtgt tgtcctcatt
    14701 gcaacctgca tattatgcgg tgtgacggga attttcggaa atgattctca aaattctcca
    14761 aaaccgcaga cgcccgatac ggcagcaacc gaaaatatga catttccgag caaggtcgat
    14821 tcgctcacat taaaagtagg cgaatcaaag cttattgaac tgtcatccga aaaagcaaaa
    14881 tccgttacca aatggacaag ctcggacagt aaaattgtta ccgttgatga cggcggaagg
    14941 gttgacgctc tcaaagaggg tacggctctg atttctgcca tttcaaaaga caaatcaaag
    15001 tcggaatttc aggttacggt ggcaaaatca accacgaaaa aacagcaaag ctactcaacc
    15061 tgtataacgg caaatcttga caaacttgaa aacaataagc gtaacacggc aaaaaacctg
    15121 tacgcaatca aggtcaaccg cacggcaaac tgcgtgacgg tttacacata tgacgaaaag
    15181 ggcaagtaca caatccccgt aagggcgatg atttgctcca caggtcttga caattcgaca
    15241 atcacgggtg actacacaat cggaatcaag tccgaatggc tttcccttgt gggcgatgtt
    15301 ttcggaagat acatcagcgg aatttcgggc gattatcttt tccactccgt tccctactac
    15361 tcaatgagcg aagaagattt ggagcttgag gagttcaaca agcttggcga acaggcatca
    15421 caaggatgcg taagacttgc ggtttcggat gcaaagtggg tttatgacaa ctgccccgca
    15481 ggcacgaatg taagcatata tgacgacgca gaaaatgcag gccctctcgg aaaaccggat
    15541 gcaatcaaaa tcaccgattt caccaacaaa tgggatccga cagacagcaa taaaaaatgc
    15601 tcgtatgcaa aagcaacacc aataatcagc ggtgcaaacg attacacaat caaaagtggc
    15661 ggcgaatttt acgcccttgc aggagtaaca gccgttgaca cctgcggcaa cgacataaca
    15721 tcgaatatcg aagttttcgg caatgtgata accacccgaa aaggcaagta caaggtaaca
    15781 tattcagtca ccgatgtgct taaaagaaca tcaagcgtaa cgattacggt aacggtgcaa
    15841 taaacatggt gcgccactgt tctccgagcg gagcttttaa attgaaagtg gaaaattgaa
    15901 aatgtaaaat aaaaatgcgg ttggcaatgt gccaccgcat tttttatgtt cgtgtgttcg
    15961 tgcagacggt tttaatagta aattacaaat gttgcccgag cataacatag caattgtttg
    16021 tacatacagt agcggcggtc agtgaccgcc atttgatttg gttgcaaagc caaatcaacc
    16081 acacagcaac atacatattt tgaccaagta taacattcca attatttttg caatgtatgt
    16141 tttaggggga accgtgttcg cccgttcgta tgcaacgcat acgattgcac gcaatgcgtg
    16201 caaggttcaa tacacaatta taatcacatc aaaacatata tgattaaaca aaatatttca
    16261 tcaaggcggg cggccgatgt gtgcagtgta gtaacatagt atacaacagt gcaaagacat
    16321 agtatacagt t
//
