LOCUS       c00018_gnlPro..        13033 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MGODJNPI_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 23:37:22
            Original ID  :: gnl|Prokka|MGODJNPI_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13033
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13033
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[285:3825](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(286..3825)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13033
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13033
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(286..3825)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_1"
                     /sec_met_domain="PFOR_II (E-value: 1.8e-19, bitscore: 59.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 2.9e-82, bitscore: 265.2,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 3.1e-33, bitscore: 104.7,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-14, bitscore:
                     43.0, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.4e-11, bitscore: 34.7,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 8.6e-08, bitscore: 21.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 7.4e-10, bitscore: 28.2,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4e-05, bitscore: 13.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 2.5e-21, bitscore: 64.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGNSAVAHVSYAFTDVAAIYPITPSSVMADLTDKFSAQGAKNLF
                     GRQVQVTEMQSEGGASGAVHGSLAAGALTTTYTASQGLLLMIPNMYKMAGELLPGVIHV
                     SARALTSHALSIFGDHSDIYACRQTGYAMLCSNNPQECMDLAAVAHLAAIEGRVPFLHF
                     FDGFRTSHEIQKIEEWDYADLADMLNWDAVEAFRRRALNPEHPVTRGTAQNDDIFFQAR
                     EACNKYYDAVPEVVVKYMDKVNAKIGTDYKPFNYYGAEDAEHVIVAMGSVCDCTEEVVD
                     YLNAAGEKVGLLKVHLYRPFVADYMLRELPKTVKTISVLDRTKEPGSIGEPLYLDVLAA
                     INGSDFAGVKVYTGRYGLGSKDTTPGDIIAVYRNAESETPKRRFTIGIVDDVTNLSLPI
                     VENPDTTPKGTHSCKFWGLGADGTVGANKNSIKIIGDNTDMYAQGYFAYDSKKSGGLTV
                     SHLRFGKTPIKSTYYISKADFVACHNPSYVDKYDIVDDLKEGGSFLLNCPWDTEELSER
                     LPGKMKKILAERHINFYTIDGIKIGKEIGLGGRINTVLQSAFFKIADIIPADKAKELMK
                     AAAKKSYMKKGQAIVDMNYAAIDRGMEDLKKVEIPADWANAVDNSVADKAEGNGALVEY
                     VNEILKPVNAYKGNKLPVSTFMDHVDGTAPNGSAAYEKRGIAVDVPEWNPENCIQCNRC
                     AIVCPHAVIRPVAMTADELAKAPEGTKSLPMMGLKDLNFVMTVSTLDCTGCGACAQVCP
                     GKKGAKALTMQPIDSQRPKQAVFDYALTLEDKPEVHEKFKFTTVKGSQFKQPLLEFSGA
                     CAGCGETPYAKLVTQLFGDRMFIANATGCSSIWGASAPATPYTKNKKGYGPAWQNSLFE
                     DNAEFGLGMALGQKAIRNRLIEYVEGIQKDTDSADLKTACQNYLDTVTDSTSSRPATDA
                     LIAELEKNTEDAKVGELVKKTLVDKDELAKKSMWIFGGDGWAYDIGFGGLDHVIASGEN
                     VNILVFDTEVYSNTGGQASKATPVGSVAQFAAAGKAVKKKDLAAIAMSYGYVYVAQCAM
                     GADNNQVLKAMVEAESYNGPSLVICYAPCINHGIKGGMGIAQLEEKKAVEAGYWNIFRY
                     DPRLADEGKNPFMLDGKAPSASYRDFIMGEVRYNSLTRSFPERAEKLFEKAEKVAADKY
                     AHLEKLASLPDAE"
     CDS             complement(4229..4480)
                     /locus_tag="ctg18_2"
                     /transl_table=11
                     /translation="LQRNDFVIKLNKNRDLTTGSITGGLWSFAVPLMLGNVFQQFYNLA
                     DTWIVGKYVGDNALAAVGSSYDRFFVYGFKRSDKAFIN"
     CDS             4544..4720
                     /locus_tag="ctg18_3"
                     /transl_table=11
                     /translation="MIAFFVANTKLHFAHGALDITVVLAVTNFLEGKFEPTCYRIVNRK
                     KFSVFGTSCNNVA"
     CDS             4710..5150
                     /locus_tag="ctg18_4"
                     /transl_table=11
                     /translation="MLRENIRKQISTIIKSIIPSMMYLATRFHTKIFTNHSISNSTQSA
                     LLSLSVPYLPCIKLANLLNNPRIKFILSAKSGNYKNHLSTILSQAGRTFNKHLTIYVTK
                     SAENELCRVNAFFCVTAVVVSADFHSVVLCKNRTADKYCAFA"
     CDS             complement(5022..7436)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) B12-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pterin_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_5"
                     /sec_met_domain="B12-binding (E-value: 5.6e-22, bitscore:
                     67.5, seeds: 91, tool: rule-based-clusters)"
                     /sec_met_domain="Pterin_bind (E-value: 2.1e-42, bitscore:
                     134.8, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNIVVFKNFSNFSEYLNQKNFILLDGATGTLIQKSGVKYDHVPE
                     VLNITHPELIESFHRRYIDAGSDIVYANTFGANAYKLQDSGYSVEEIIGAGVKIARKAV
                     EGTDALVALDIGPIGQLLEPAGSMKFDEAYEYYKQQILAGKDADVIVFETMTDLYELKA
                     AVLAAKENCDKPILTTMTFERNGRTFTGVSPACAAVTLTGLGVDALGVNCSLGPDELEP
                     VVSEMSKYTNLPLVIKANAGLPDPNSNEYNIMPDKFAECVCSLLKYGVKVIGGCCGTNP
                     DYIAKIKSEVADKEYQPQTKSVDTTVCSSTTVVEINGPRIIGERINPTGKKLFKQALVE
                     NNIDYILTQALSQVQGGAEILDVNVGHPEIDEKKMMVRVLKAIQSVCDVPLQIDSTKPE
                     VIEAGLRYYNGKPILNSVNGEEQSLATVLPLVKKYGASVVGLALDENGIPKTAEGRFEI
                     AKRIVERAEAVGIDRKDVYIDCLTLTVSAEQAACRQTLEALHRVKTELGCKTCLGVSNI
                     SFGLPNRELVNRTFLTMAMEQGLDLPIINPNVESMTGAVRAFRVLNGIDKNSLEFINAY
                     NDAVPAAPVKKADSNVDIFAAVYNGLKNEGAAATAKLLETTDAMQVVNEMLIPALDRVG
                     EDFEKNKIFLPQLIQSANTAQECFDVIKKHLTKTSGTPVSKGKIIVATVKGDIHDIGKN
                     IVKVLLDNYGYTVVDLGRDVDPQLIVDTAVEQNITMIGLSALMTTTLKSMEDTIRLVRE
                     CKELQNPDGSSKCTIFVGGAVLTKDYAMKIGADYYCRDAKESVDTAKLVLG"
     CDS             complement(7414..8058)
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MITLDRLNRKEAIRYLGGAGISLNYRMDVLMDECEKEILKTAEPR
                     FLYVERKAPFDDILLGNDIKKHLEGCHTAVMMCATIGSEIDKLIRISQISDMARAVVLD
                     SFASVAVEQVCQKVDEILAEKYSGKYMTFRFSPGYGDYPIEMQKEYLRILDAPRKIGLT
                     TGDSCLLVPSKSVTAVLGISDNPIERRKRGCAICSMKGKCRFRRNGEHCGV"
     CDS             complement(8055..8915)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MTHFR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_7"
                     /sec_met_domain="MTHFR (E-value: 4.5e-86, bitscore: 278.0,
                     seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISDLKPDFI
                     SVTYSAGGSGSKSRTCEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENI
                     LALRGDRVEGVEPQKDFTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRK
                     KVESGASHLISQLFFDNSVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGAS
                     LPAKFAKIMQKYDTRPEALRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEA
                     VSSLL"
     CDS             complement(9289..10659)
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="MMEQVNVTLTETIKVLLDDKKFSTLRDILITMKPFDIAAVFENLQ
                     DEKMPILFRILPKELAAETFVEMDDETQEFLIHGFSDSELKEVVDELFVDDAVDLIEEM
                     PANVVKRILRQADKDMRKQINELLKYPEDSAGSIMTTEFIVLRPDMTAEMAIKRIRRTG
                     VDKETIYTCYVTDANNKLIGITTVKDLLLAEDDELVKSIMEENVISVTTLADQEQVAQM
                     FSNYNFLALPVVDNENRLVGIVTIDDAIDVIQEEATEDIEKMAAVLPSDKPYMKTSVFG
                     LYKKRAPWLLILMLSATFTSAIISSFEAVLANVLILSSFIPMITGSGGNAGSQASVSVI
                     RALSLGEIHFRSIFLVLWKEFRVSILCGITLAAANFVKLLLFDLNGQENAFMIALVISL
                     TLVGTIIMAKLVGSSLPLLASKVGFDPAVMANPLISTVCDSLSLLIYFGVAKLILHL"
     CDS             11080..11721
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="MTDMVKKYVPYAVIILLVYMLLPLVFIPGAMQKFSPVAYDFVFPI
                     TAIGCSAHYCSKHGLDFLFALIAPIIYLPSMLIYNGGFSSSTLSTNLILLVVYLVAGIF
                     GLFLGDLAFGDKRRQKEKAEQEEAEEMLLEAKRREKEELENMTSSSKKSERKAPYRQER
                     KPARRPSPAPQKTETADDDDFDYDKYLSGIDRKQDPNESEIDDILNEYRH"
     CDS             complement(12040..12948)
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="MKNIIKKITAIAMCGVLTVGWVLMTGAVSEYEDRKDFEVTGTTQK
                     ISNNQIFVTTTGYTENTAKNFGAMFISMDYQKYSVMFKDCIDAPKFVNLPKNQEFTRHM
                     ITADNRYFGNTGMKFNYDSTGGEYVKIRIKLSDYFPDVFNDDGTMTGKLSDGTYKNFDF
                     TYEGFGTDSSGKPCYATSGAYFVSGGAVTSFVPDKNGYAEFYISRQLGEDTGLMAYKYC
                     RLKNGAECKTTIGGKLNCLTCGDAYPDGNITVGDATSVQKYVVGIVKFGKTQLFNSDVN
                     HDGEISVVDATLIQKYIVGLS"
ORIGIN
        1 tgtataccat gtccttgcac aggtggttac catgttgcac ttgacacaat gaacgcccct
       61 acgggtttac atttataaat tattatttaa acggaaaaat actgccgttg cctgtggtcg
      121 aaccgatttt gcaatcggtt cgattggcgt tcactgaacg ccgctacaat tttccacttt
      181 ccattttcaa ttttcaatta aaaaaatccc gaacacggca aatgccatat tcgggagaat
      241 tttttattta ttcacatatt cactttgtac aagctttagc caaaattatt cggcatcggg
      301 aaggcttgca agcttttcaa ggtgagcata cttatcagca gcaacctttt cagccttttc
      361 aaagagtttt tctgctcttt cggggaatga acgagtgagt gagttataac gaacttcgcc
      421 catgatgaag tcacgatatg atgcagaagg agctttaccg tcaagcatga acggattctt
      481 tccttcgtct gcaagacgag gatcataacg gaagatattc cagtaacctg cctcaacagc
      541 ctttttctcc tcaagctgag caatgcccat gccacccttg ataccgtggt tgatacacgg
      601 agcgtagcag attacgagtg acggaccgtt gtagctttca gcctcaacca tagccttgag
      661 aacctgattg ttgtcagcac ccatagcgca ctgtgcaaca taaacatagc cgtagctcat
      721 tgcaatagcg gcgaggtctt tcttcttaac agccttacct gcggcggcaa actgtgcaac
      781 cgaacctaca ggagtagcct ttgaagcctg accgcctgtg ttagaataaa cctcagtatc
      841 gaatacgagg atattaacat tttcgcctga tgcgattaca tggtcaagac caccgaaacc
      901 gatatcgtaa gcccaaccgt caccgccgaa gatccacatt gacttcttag cgagttcgtc
      961 cttgtcaacg agtgttttct taacaagttc gccaaccttt gcatcctctg tgttcttttc
     1021 gagttcagcg ataagagcgt ctgttgcagg acggcttgaa gttgaatctg ttactgtgtc
     1081 gagatagttc tgacaagctg tcttgaggtc agcgctgtct gtatccttct gaataccctc
     1141 aacatactcg ataagtctgt tgcggatagc cttctgaccg agagccatac caagaccgaa
     1201 ctctgcgtta tcttcaaaga gtgagttctg ccaagcagga ccgtaaccct tcttattctt
     1261 tgtataaggt gttgcaggag cagatgcacc ccaaattgat gaacagcctg ttgcgttagc
     1321 aatgaacatt ctgtcaccaa aaagctgtgt aacaagcttt gcatacggtg tttcaccgca
     1381 gcctgcgcaa gcgcctgaga attcaagcaa cggctgtttg aactgactgc ccttaactgt
     1441 agtgaacttg aacttctcgt gaacttcagg cttatcttca agtgtgagag cgtagtcaaa
     1501 tactgcctgc ttaggacgct gtgagtcgat tggctgcatt gtgagagcct tagcgccctt
     1561 cttacccgga caaacctgag cacaagcgcc gcaacccgta cagtcgagtg ttgaaactgt
     1621 cattacaaag ttgaggtcct taagtcccat catcgggagg ctctttgtac cctcgggagc
     1681 ttttgcaagc tcatcggctg tcatggcaac aggacggatt acagcgtgag gacatacgat
     1741 tgcacatctg ttacactgaa tacagttttc aggattccat tcgggaacat caactgcgat
     1801 acctctcttt tcataagcgg cagaaccgtt aggagcagta ccgtcaacat gatccataaa
     1861 tgttgaaaca gggagcttgt tacccttata tgcatttaca ggcttgagga tttcgtttac
     1921 atactcaacg agagcaccgt taccctctgc cttgtcggca actgaattat caacagcgtt
     1981 agcccaatca gcaggaattt caaccttttt gaggtcttcc ataccacggt cgatagcagc
     2041 gtagttcata tctacgatag cctgaccttt cttcatgtat gacttcttag cggcagcctt
     2101 cataagctcc ttagccttgt cggcaggaat gatatctgca atcttaaaga atgctgactg
     2161 aagaactgtg ttgatacgac cgccgagacc gatttcctta ccaatcttga taccgtcaat
     2221 tgtgtagaag ttgatgtgtc tttcagcgag aatcttcttc atcttacccg ggagacgctc
     2281 ggaaagctct tctgtatccc atgggcagtt aagaaggaat gaaccgcctt ctttaaggtc
     2341 atcaacaata tcgtacttgt caacataaga cggattgtga caggcaacaa agtctgcctt
     2401 tgaaatgtag tatgttgact taataggagt tttaccgaaa cgaaggtgag aaactgtaag
     2461 accgcccgac ttctttgagt catatgcaaa gtagccctga gcgtacatat cggtgttatc
     2521 gccgataatc ttgattgagt tcttgttagc accgacagta ccgtcagcac caaggcccca
     2581 gaacttacag ctgtgtgtac ccttcggagt tgtatcggga ttttcaacaa tcggaagtga
     2641 gaggtttgta acatcatcaa caatgccgat tgtaaatctt ctcttaggtg tttcgctttc
     2701 agcgtttctg taaacagcga tgatgtcgcc tggtgttgta tcctttgagc caagaccgta
     2761 tctgcctgtg taaaccttta cacctgcaaa gtccgaaccg ttgatagcgg cgagaacatc
     2821 aagataaaga ggttcgccga ttgaaccggg ttcctttgtt ctgtcaagaa cagagattgt
     2881 cttaacagtc ttaggaagct ctctgagcat atagtcggca acgaaaggtc tgtaaaggtg
     2941 aactttaaga agaccgacct tttcgcctgc ggcattgagg taatcaacaa cttcttccgt
     3001 acagtcacaa acagaaccca tagcaacgat aacatgctct gcatcctctg caccgtagta
     3061 gttgaacggc ttgtagtcag tgccgatttt agcattaacc ttgtccatgt acttaacaac
     3121 aacttcggga actgcgtcat aatacttgtt acaagcttct cttgcctgga agaagatatc
     3181 gtcgttctga gcagtacctc ttgttacagg atgctcaggg ttaagagcac gacgacggaa
     3241 agcctcaact gcatcccagt taagcatatc ggcgaggtct gcgtaatccc actcctcaat
     3301 cttctgaatt tcgtgagaag ttctgaaacc gtcaaagaaa tgaaggaaag gaactctgcc
     3361 ttcaatagct gcaaggtgag caacagcggc aaggtccata cattcctgag gattgtttga
     3421 acaaagcatt gcataacctg tctgacggca agcgtagata tctgagtggt caccaaaaat
     3481 agaaagtgcg tggcttgtga gcgcacgggc tgatacatga ataacgcccg gaaggagctc
     3541 gcctgccatc ttgtacatat tcggaatcat aaggagcagg ccctgtgatg ctgtgtaagt
     3601 tgtggtcaaa gcacctgctg cgagtgagcc gtgaacagca cctgatgcac cgccctccga
     3661 ctgcatttcc gttacctgaa cctgtctgcc gaaaaggttc ttggcaccct gtgccgagaa
     3721 cttgtcggta aggtcagcca ttacggaaga aggggtaata ggatagatag ccgcaacatc
     3781 ggtaaacgca taagaaacat gagctactgc gctgttacca tccatagttt tcatttttct
     3841 tgccaatgga atcgtcctcc tttttaatca aagcggcaaa ggaaatgatg ccgcataaat
     3901 tttcgatacc cgttaattac gcaccgtaaa tcaacaagcg gtacggatac tttgtatcat
     3961 cttaaatttt atcacttaaa caccgatttg taaagtgttt tacacaagaa attcaaagca
     4021 ggatatatat ttttgtttcg ttttttacaa aaaagttttt tatatttact tgtttctgtc
     4081 aaaatacttt gttgttgatt ttttaaaaat caataacaaa ggttttggtt atttgtacaa
     4141 acgattgcaa tgttacgctc gggcataata tgttttttga cattgcaaac tgtctgcacg
     4201 aattgggtac ggcggctcgc cgtaattttc aatttataaa tgctttatcg cttcgcttaa
     4261 atccgtacac aaaaaatcta tcatatgacg agcctactgc cgcaagggca ttgtcgccca
     4321 catattttcc gactatccat gtatcggcaa ggttgtaaaa ctgctgaaac acattgccga
     4381 gcataagcgg tactgcaaaa gaccacaggc cgcctgttat actgcctgtg gtcaaatctc
     4441 tgtttttatt tagttttatc acaaaatcat ttcgttgcaa ccgcagattc tgcggtcata
     4501 tttttttgtt aaattcactt ccgcatttcg gacagcgaac agtatgattg ccttttttgt
     4561 tgcgaacacg aagctgcact ttgcacacgg ggcacttgat ataacggtag tccttgcggt
     4621 cacgaatttt cttgaaggta agtttgaacc aacctgttac cgcattgtaa atcggaagaa
     4681 attttctgtt ttcggcactt cttgcaacaa tgttgcgtga gaacatacga aaacagataa
     4741 gcacgataat caagagcatt attccgtcaa tgatgtatct tgcaacacgg ttccacacaa
     4801 aaatattcac gaaccacagt ataagcaaca gcacccagag tgcattgttg agcttgtccg
     4861 tgccgtatct gccctgcata aaattggcga atctgttaaa taatcctcgc ataaagttca
     4921 tcctttccgc aaaaagcggt aattacaaaa atcatctttc caccatttta tcacaggcag
     4981 ggcgtacatt caataaacat ttgacgatat atgtcactaa atcagccgag aacgagcttt
     5041 gccgtgtcaa cgctttcttt tgcgtcacgg cagtagtagt cagcgccgat tttcatagcg
     5101 tagtcctttg taagaaccgc accgccgaca aatattgtgc atttgcttga gccgtcggga
     5161 ttctgaagtt ccttacattc tcttacaagc cttattgtgt cttccatgct cttgagagtt
     5221 gttgtcataa gagccgaaag tcctatcatt gtaatattct gttcaacggc agtatcaaca
     5281 ataagctgcg gatcaacatc tcgaccgagg tcaacaactg tgtagccgta gttatcgaga
     5341 agaaccttta caatgttctt gccgatatcg tgaatgtcac cctttacggt tgccacaata
     5401 attttgccct tgcttacggg agttccgctt gtctttgtaa ggtgcttttt aattacatca
     5461 aagcactcct gagctgtgtt tgcgctttgg ataagctgtg gaaggaagat tttattcttt
     5521 tcaaaatctt cacccactct gtcaagtgca gggataagca tttcgtttac aacctgcatt
     5581 gcatcggttg tttcaagaag ctttgcggtt gcggctgcac cttcgttttt aagtccgtta
     5641 taaacagccg caaaaatatc aacattgctg tctgcctttt taacgggagc ggcaggaaca
     5701 gcatcgttat atgcgttgat aaattcaagc gagttcttgt caatgccgtt aagcacacgg
     5761 aatgctctta cagcgcctgt catcgactca acattcgggt tgataatcgg caaatcaagt
     5821 ccctgttcca tagccattgt aaggaaagtt ctgttgacaa gctcacggtt cggaagtccg
     5881 aacgaaatgt ttgatacacc gagacaggtt ttacagccaa gttccgtttt tactctatgc
     5941 aaggcttcaa gagtctgacg gcaagccgcc tgttctgcgg aaaccgtaag agtaagacag
     6001 tcgatatata catcttttct gtcaatgccg acagcctcgg ctctttcaac aattcgtttt
     6061 gcaatctcaa atctgccctc ggcggttttc gggataccgt tttcgtcaag tgcaagtccg
     6121 acaacagacg caccgtactt tttgacaaga ggaagaaccg ttgcaaggct ctgttcctca
     6181 ccgtttacgg agttcagaat cggtttgccg ttgtagtagc ggagtccggc ctcaataacc
     6241 tcgggctttg tggagtcaat ctggagcgga acatcacaca cactctgaat agccttaaga
     6301 acacgcacca tcatcttttt ttcgtcaatt tcgggatgac ctacattgac atcaagaatt
     6361 tccgcaccgc cctgaacctg actgagagcc tgagtgagga tatagtcaat attattttca
     6421 acaagcgcct gcttgaacag ctttttacct gtggggttaa ttctttcgcc gataattctc
     6481 ggaccattga tttcgacaac cgtcgttgaa ctgcaaacgg ttgtgtcaac gctctttgtc
     6541 tgaggctgat attctttgtc ggcaacctct gacttaattt ttgcaatata atcgggattc
     6601 gttccgcaac atccgccgat aaccttaaca ccgtatttga ggagtgaaca aacgcactcg
     6661 gcaaatttgt cgggcataat gttgtactcg ttgctgttag gatcgggcaa acctgcgtta
     6721 gccttgatta caaggggaag atttgtgtat ttcgacatct cggaaacaac gggttcaagc
     6781 tcatccggac cgagtgaaca gtttacaccg agagcgtcaa caccgagtcc cgtaagagtg
     6841 acagccgcac aggcagggga tacacccgta aatgttcgtc cgtttctctc aaaggtcatt
     6901 gttgtgagga taggcttgtc gcagttttct tttgcggcaa ggactgcggc tttaagttca
     6961 taaaggtcgg tcattgtttc aaaaactatg acatcggcat ctttaccggc aagaatctgc
     7021 tgtttgtaat actcataagc ctcgtcaaat ttcattgaac cggcaggttc aagcaactga
     7081 cctatcgggc cgatatcaag ggcaacgaga gcgtctgtac cctcaacggc ttttcttgca
     7141 atcttaacac cggcgccgat gatttcttcc acgctgtaac cgctgtcctg aagcttgtag
     7201 gcatttgcac cgaaggtgtt tgcgtacaca atgtcagatc cggcatcaat atacctcctg
     7261 tgaaagctct cgataagctc ggggtgagta atgttcagca cctcaggcac atggtcgtac
     7321 tttacaccgc ttttctgaat gagagttcct gttgcaccgt caagcagaat aaaattcttt
     7381 tggttgagat attcactaaa gtttgaaaaa ttcttaaaca ccacaatgtt ccccatttct
     7441 tctgaagcga catttgcctt tcatactgca aattgcacac cctcgttttc ttcgttcaat
     7501 cggattgtct gaaattccga gaaccgccgt aaccgacttt gacggcacaa gcagacagct
     7561 gtcgcctgtt gtaagaccta tttttctcgg agcgtcaagt attctcagat actccttctg
     7621 catctcaata ggatagtccc catagccggg gctgaaacgg aaggtcatat actttccgct
     7681 gtatttttcg gcaaggattt cgtcaacctt ttgacacacc tgttcaacgg caacgcttgc
     7741 aaagctgtca agcacaaccg cccttgccat atcggaaatc tgacttatac ggataagctt
     7801 gtcaatttcc gaaccgattg tcgcacacat cataacggct gtgtggcagc cctcaaggtg
     7861 cttttttata tcattgccga gtaaaatatc gtcaaacgga gctttgcgtt caacatagag
     7921 aaatctcggc tctgctgttt tcaatatttc tttttcgcat tcatccatca gcacatccat
     7981 gcggtaatta aggctgattc ctgcaccgcc gaggtagcgt atagcctctt tgcggtttaa
     8041 tctgtcaagc gttatcataa aagacttgac accgcctccg taatttttct tgcaacatac
     8101 gggttgttca ttgtgtagag gtggatgccg tcaacaccgt gtgcgataag gtcaacaatc
     8161 tggtcaaccg catatgcaat gcctgcgtca cgcaaagcct cgggccttgt atcatacttc
     8221 tgcataatct ttgcaaattt tgcaggaagg cttgcaccgc acattgaaac cattctttca
     8281 atctgacttt tgcttgttac aggcataata cctgcctcaa tcggaacatt cacgcctgca
     8341 atcttcgctc tttcaagaaa gcgatagtaa acggagttgt caaagaaaag ctgtgaaata
     8401 aggtggcttg cacccgactc aacctttttg cgaaggttgt gaatgtcctc aacctcatcg
     8461 gttgcctcgc tgtgaacctc gggataacaa gcaccggcaa tgtcaaaatc accctgtgac
     8521 gcaatatatc tgcacaaatc gcttgcataa gtgaaatcct tctgcggttc aacaccttca
     8581 accctgtcac cacggagtgc aagaatattc tcaatgccgt tctctttaaa aagcgcaagg
     8641 ttgcggtcaa tatcagcctt tgtgctgtta atgcaggtga ggtgtgccac ggattcaact
     8701 ccgaaatctc tcttgatttt tgttgcgatt tcgcaggtac ggctctttga accgctgccg
     8761 cctgcgctgt atgttacgct gatgaagtca ggctttaaat ccgaaatttc ttcaagcttg
     8821 ccgtaaaccg attcaatcgg agaggtcttt ttaggcggaa atacttcaaa agaaaaaact
     8881 gtttttccgc tgttaaataa attgcttatt ttcatatata aacacctcgg taatggtttt
     8941 gttaaacttg attaattata gcataaataa tttttgcata caatactgtt ttggtgggtt
     9001 ttgtcgttta aggctatcat ttttttggaa gttttggtat aagcaaaaat tatatcaaag
     9061 agttttataa taattataat tttgttaaca gaccaaattc accattatat tctgtagtgg
     9121 cgaaccgtgt tctccctaca gagtatacat ttactttcat aataaagcaa aaattgcatc
     9181 aatgccgtat tcaggcatct gatgcaattc ctttatccga gtatcttctc gaatagattg
     9241 cggtggcaca ccgccgaccg caatttccaa ctttcaattt taaaaaaatc acagatgcaa
     9301 aatcaacttt gcaacgccga aatagataag caatgaaagc gagtcgcaga ctgttgaaat
     9361 gagcggattc gccataacgg cagggtcaaa accgaccttg cttgccaaaa gaggcagact
     9421 gctgccgaca agctttgcca taataattgt gccgacaagc gtaagcgaaa ttacaagggc
     9481 aatcataaat gcgttttcct gaccattgag atcaaacaaa agcagtttta caaagtttgc
     9541 cgccgcaagg gtaataccgc aaagaattga caccctgaat tctttccaca gcacaaggaa
     9601 aatgctcctg aaatgaattt caccgagcga caacgcacgg attacggaaa ccgacgcctg
     9661 agaacctgcg ttaccgcccg aacccgtaat catcgggata aacgatgaga gaatcaaaac
     9721 atttgcaagc acagcctcaa atgatgagat aatcgcactt gtaaaggttg ccgaaagcat
     9781 gagtataagc agccacggcg ctctcttttt gtacagaccg aaaacgcttg ttttcatata
     9841 cggtttgtca gacggcaata cggctgccat cttttcgata tcctcggtag cctcttcctg
     9901 aataacatca atagcgtcgt caattgttac gataccgaca agtcggtttt cgttatcaac
     9961 aacaggaaga gcaaggaagt tatagtttga gaacatctgg gcaacctgct cctgatcggc
    10021 aagagtagtt accgagataa cattttcctc cataatcgac tttacaagct cgtcatcttc
    10081 ggcaagcaaa aggtctttta cggtggtaat accgataagc ttgttgttgg catcggttac
    10141 atagcaggtg tagattgttt ccttgtcaac acctgttctt ctgattcttt taatagccat
    10201 ttcagccgtc atatcgggac gaagcacaat aaactcggtt gtcataatcg agcctgcgct
    10261 gtcctcggga tatttcaaaa gctcgttaat ctgctttctc atatccttgt cggcctgtct
    10321 taaaatacgc tttacaacat tagcaggcat ttcctcaata aggtcaacgg cgtcatcgac
    10381 aaataactca tcgacaacct ctttcagttc gctgtcgctg aagccgtgga taagaaattc
    10441 ctgagtttcg tcatccattt cgacaaaggt ttccgccgca agctcctttg gcagaatacg
    10501 aaacagaatc ggcatttttt catcctgtag attttcaaaa accgccgcaa tgtcaaacgg
    10561 tttcatcgta atcaaaatgt cacgcaaagt gctgaacttt ttgtcatcaa gcaacacttt
    10621 gatagtttcg gtaagggtta cgttaacctg ttccatcatc ttttcctcct ttttaattca
    10681 attggaagta aagacggtgt caccctgagt attaaattaa atcaattcaa attaaaataa
    10741 aaatacaaag caaaatcaat aaaacaaaat gaacgcacaa gcgcacattc tgttgcaact
    10801 tcgcccgggt acagcgcctt tattaccgtc tgcgtccatt aagttttcac ctcattcgca
    10861 tttaaattcg ggcaaaagcc cgtacctatt tattttattc ttttttatgt ccgatgtcaa
    10921 cggatttatc cgctaaaaat ccactttgca aacattttac attattctct gtaacagcct
    10981 ggtaactcgg tataatattt cttgcttttt gaagtgtatc aatgtataat aaatatgcat
    11041 gatttaaaat aaaatttcaa agattggaga ttaaccgtta tgacagatat ggttaaaaaa
    11101 tatgttccct atgcggtaat aattttgctt gtttatatgc tgttgccgct tgtgtttatt
    11161 ccgggcgcaa tgcagaagtt ttcacccgtt gcatatgact ttgtgttccc gattacagca
    11221 atcggctgtt cggcacacta ctgctcaaaa cacggacttg actttctctt tgctctcatt
    11281 gcgccgatta tttatcttcc gagtatgctc atctacaacg gcggattttc ttcaagcaca
    11341 ctttcaacaa accttattct cctcgtagtt tatcttgttg ccggaatttt cggacttttc
    11401 ctcggcgacc ttgctttcgg tgacaagcgc cgtcagaaag aaaaggcaga acaggaagaa
    11461 gcagaggaaa tgctccttga ggcaaagcgc cgtgaaaagg aagagcttga gaacatgact
    11521 tcatcaagca aaaagtccga aagaaaagcg ccttacagac aggaacgcaa gcctgcacgc
    11581 agaccgtcgc ctgcaccgca gaaaaccgaa acagcagatg acgacgattt tgattatgac
    11641 aagtaccttt ccggtattga cagaaagcaa gatccgaacg aaagcgaaat tgacgatatc
    11701 ttaaatgaat acagacacta acggcgagcc gccgttccca attcgtgcag atagtattta
    11761 taagggcgaa aataaaatgc ccgagcagaa ctctataact aaaaatgtaa aattaaagtc
    11821 ggaaagacaa cttgcgaaat gcaaagcatt gtcttcccga ctgtttttgt ttaatcagca
    11881 ggggcattca ttggacgccc gatttgattg aattttatgt tttcgcaaaa tcagtcgatg
    11941 ttatggaagt tgtgtgtaat ttgcgacaca tatataatct gtcttaacaa aaagattgta
    12001 ccattacttc gtcaatttgc ttttatatgt aatttttatt taactcaacc caacgatata
    12061 cttctgaatc aaggttgcgt caacaacact gatttcgccg tcatggttta catcgctgtt
    12121 aaaaagctga gtcttgccga attttacaat acctacaaca tatttctgaa cagatgttgc
    12181 atctccaacc gtaatgtttc cgtctggata tgcatcaccg caagtcaggc agttcaattt
    12241 gccaccaatc gttgttttac actctgcgcc gtttttaagt ctgcaatatt tataagccat
    12301 aaggcccgta tcctcgccaa gctgtcttga aatataaaac tccgcatagc cgttcttatc
    12361 ggggacaaaa gatgttaccg cacctccgct gacaaaatat gcgcccgagg ttgcatagca
    12421 aggtttgccg ctgctgtctg taccgaaacc ctcatatgta aagtcaaaat tcttgtatgt
    12481 gccatcgctg agttttccgg tcattgtgcc atcatcatta aagacatcag gaaaatagtc
    12541 ggagagttta atccttatct taacatattc tccgcctgtt gaatcataat tgaatttcat
    12601 acccgtatta ccaaaataac gattatccgc tgttatcata tggcgagtaa attcctgatt
    12661 tttcgggaga tttacaaact tcggtgcatc aatacagtcc ttaaacatca cgctgtactt
    12721 ttgataatcc attgatatga acattgcccc gaaattcttt gccgtatttt cggtatatcc
    12781 cgttgttgta acaaaaatct gattgtttga gattttctgc gttgtacctg taacttcaaa
    12841 gtccttgcga tcttcatact cgcttaccgc acctgtcata agaacccaac cgacggtaag
    12901 cacaccgcac attgcgattg cagttatttt tttaattata tttttcattg tttttcctct
    12961 ttctatcagt aggggcgctc attgtgtcaa gtgcaacatg gtaaccacct gtgcaaggac
    13021 atggtataca aat
//
