LOCUS       gnlProkkaOEADKHHE_23   15425 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OEADKHHE_23.
ACCESSION   gnlProkkaOEADKHHE_23
VERSION     gnlProkkaOEADKHHE_23
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 11:26:56
            Original ID  :: gnl|Prokka|OEADKHHE_23
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15425
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15425
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4691:5425]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4692..5425
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..15425
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15425
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             3..71
                     /locus_tag="ctg23_1"
                     /transl_table=11
                     /translation="MSRLNSDALVTQLPSNSLTILC"
     CDS             398..1051
                     /locus_tag="ctg23_2"
                     /transl_table=11
                     /translation="MDYQSIVTFVMEMAGSVAFAASGAMVGVERNMDIFGVSVLGVATA
                     VGGGMIRDIVLGIIPPAVFTNPVYALVSVLASCIVFFIFYFKRELLQGHRRETYDKIML
                     AMDSVGLGIFTVVGVNTGIRQGYMDNVFLLVFLGTITGVGGGLLRDMMASVPPYIFVKH
                     IYACASIIGAVVCVYMNRFVGNVQAMVVSSIVVVLIRYLAAHYRWNLPRLSPHE"
     CDS             complement(960..1472)
                     /locus_tag="ctg23_3"
                     /transl_table=11
                     /translation="MRKKLNITEGIFPMPVLMVATYNEDGSINVMNAAWGTMQERDTVA
                     LNLTETHKTVQNIKARGAFTVSIADAAHVTEADYFGVESGNREPDKFARSRLTATKSET
                     VDAPIINNFPPRTKRQSDKLSLTALNITCLILYGILPIHVVTAWADSSGNVLPDIGSAP
                     LQLMILP"
     CDS             complement(1963..3261)
                     /locus_tag="ctg23_4"
                     /transl_table=11
                     /translation="MEYIILLIFSFFTEAVILWQYAASLFSPSHSGKKRLTLLSVLYVL
                     LFFLSLLGQTWLNIISFFVINTVFLYIMFNLKLLLALFHSAILTAIMGISELAVLGMIS
                     RFFPHFLLEASVGLVFYTVFSKITFFAVVYLLSWLFKGNKAAQEPYGHSEILLMFIPLS
                     SILMMFTLLSIGETTAYAPPVDFLVTICAVFLLLVNLLVFGINQYNTKRSQEYADLQLL
                     LQKESDSVEYYEMMLAQNENQSILIHDIKKHLQSIRLLNEKNDSDKINDYIQQLMESSD
                     LKETTKLCDHEMLNSILCRYQRHCNDKHIIFHTDIRSGTVQHIYPRDLTSLFCNLLENA
                     VESAENIPDSFIELTVQKKENSPFLIIILINSCQNTPVYNPEGLPISHKSDNGRHGFGI
                     KSIKKVVKQYHGNLQMYYDNDSGTFHTILTLKQ"
     CDS             complement(3268..3975)
                     /locus_tag="ctg23_5"
                     /transl_table=11
                     /translation="MRILICDDDTLIIEQLKKYIESYFESNHLKCPELVSFTSGEALLT
                     DKGEKDIVFLDIEMPGMNGIYVGNELKKANRNVIVFVVTSYSEYLDEAMRFHVFRYLSK
                     PLDKQRFFRNLKDALAYYNSITLKIPVETKQAVYSFPASQIIAIEAQGRKVIVHTARQD
                     FDSIHNMNYWLEKLPQNSFFQTHRSFIVNFEHIVDFDHSTVHLSNPQITAYLTRRKYSS
                     FRNAYLLYLESMR"
     CDS             complement(4067..4396)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 57.2; E-value: 4.5e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg23_6"
                     /transl_table=11
                     /translation="MGNRIKIRRKELRIKQAELAERLNISNSHMSSIENGRQKPSLDIF
                     IQICNLLNVTPDYLLLGSMHAYNIPQDIIDKLRLCNQSDIELAGDFIELLVKRNNKATH
                     NEPKL"
     CDS             4692..4841
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_7"
                     /sec_met_domain="TIGR04223 (E-value: 2.5e-14, bitscore:
                     44.5, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKEVTKSVAKGMKAALDVVLRTEANTASCLIMYQPKAPKELMNY
                     RRNK"
     CDS             4841..5425
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_8"
                     /sec_met_domain="AgrB (E-value: 2.8e-36, bitscore: 115.9,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKCTDTVVNWMIRCNAINEADKELYKYALYSFFLLVSPLILAGV
                     IGFGLGSVKHGVALIFPFVVLRKFSGGYHAKNLHTCILGSGFLLFLCIMLSMHVQCDLK
                     LAIATVIASVSLITFSPIDSENRRLDTNEKRTYKKTTVFFVILFGLLDIALFLLGKYIY
                     TICFSVGILLTAGLQVPCIVKKMCKSTKNRL"
     CDS             5640..6023
                     /locus_tag="ctg23_9"
                     /transl_table=11
                     /translation="MTHKKEVVFSLLFVIMVLCTGCSDKDNGDTSKNNRTSGESFVQEE
                     TIESTDNTDNADGSSAPTPELKTPRTKKELEDALGTVNESGKWTPPAGSHIDPKTGNIL
                     NKDGVVVGTTQEPYSKARPGSQG"
     CDS             6020..6169
                     /locus_tag="ctg23_10"
                     /transl_table=11
                     /translation="MMIWCKKIMGGKDYEVYEKKLICSVFGHKCNSFDKFICNAGACCG
                     KYRN"
     CDS             6637..6795
                     /locus_tag="ctg23_11"
                     /transl_table=11
                     /translation="MALAQATKSHEPTYTINDAMDVLLSRLDEAIDDMESDRVQIVEEA
                     WAEIDAI"
     CDS             6805..6951
                     /locus_tag="ctg23_12"
                     /transl_table=11
                     /translation="MEKRKYKVVIAQSGKLDVKEKRNISFSNLNTGSMQRIFPKRLKSG
                     SCT"
     CDS             complement(7134..8846)
                     /locus_tag="ctg23_13"
                     /transl_table=11
                     /translation="MEFSAVNTIWVLVGAALVFFMQAGFAMVETGFTRAKNAGNIIMKN
                     LMDFCIGTPVFWLVGFGLMFGAGNGFIGKIGGIATEAHYGSGMLPDGVPFWAFLIFQTV
                     FCATSATIVSGAMAERTKFLSYCIYSLMISLVVYPVSGHWIWGGGFISQMGFHDFAGSC
                     AVHMVGGVAALIGAIILGPRIGKYTKDGKSKAIPGHNLTVGALGVFILWFCWFGFNGAS
                     TVSMEGDAIVSAGKIFVTTNLSAAVATVTVMIITWVRYKKPDVSMSLNGSLAGLVAITA
                     GCDTVSPTSAAIIGIASGFIVVFGIEFIDKVLKIDDPVGAVGVHGLNGAFGTLAVGLFS
                     DGSGTDWKGLLTGGGFHGFGVQFTGMIITIAWVVVTMTIIFQVIKHTIGLRVSAEEEIA
                     GLDSKEHGLASAYDGFAMAGVPTPMGTSIKAPVVTARPSAPAESVPELPKEGVHKLTKV
                     VIITRQNKLDEFMQAMNEIGVTGITITNVLGCGVQKGAPSYYRGVEMEMNLLPKVKIEI
                     VVSLVPVQKVIETAKAVLHTGQIGDGKVFVYDIENVVKIRTGEEGYLALQDTK"
     CDS             complement(9145..11244)
                     /locus_tag="ctg23_14"
                     /transl_table=11
                     /translation="MAQNIPELYGSLVFNDKVMRSKLPKDMYKALKKTIESGTHLELDV
                     ANSVAVAMKEWATENGATHYTHWFQPMTNVTAEKHDSFISPTGDGQVIMDFSGKELVKG
                     EPDASSFPSGGLRATFEARGYTAWDPTSPAFIKDGTLYIPTAFCSYSGEALDKKTPLLR
                     SMQTLDKEATNLLHIIGNKDIKHVNTTVGPEQEYFLVDKELYKQRKDLVFCGRTLIGAP
                     APKGQEMEDHYFGALKPRVAAYMHDLDVELWKLGIPAKTKHNEVAPAQHELAPVFDTTN
                     VAVDHNQLTMEVMKKVADKHGLVCLLHEKPFEGINGSGKHNNWSMITDTGVNILDPGKT
                     PAENTQFLIFLTAVIKAVDEYADVLRISVASAGNDHRLGANEAPPAVVSVFLGDELTEV
                     LKSIENDEYFAGSRAVQMDIGAKVLPHFVKDNTDRNRTSPFAFTGNKFEFRMLGSEASV
                     ANPNIILNTAVAECVHQFAEQLKDVPEDKMEDAIHELIKKTIIDHKCVIFNGNGYTDEW
                     IEEAEKRGLFNLKSTPDALPQWIADKNIELFTKYHIFTKEEIESRYEIWLESYSKILNI
                     ESNTMVEMVQKDFLPSVFAYIDKVAATAVAKKSVVSDVSTASEGKLIKELSQLADEIST
                     GLETLKADTAKALATEDPLANAKAYQTVVLSDMDELRKSVDAAETLIPDALLPYPTYDK
                     LLFSV"
     CDS             11661..13082
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_15"
                     /sec_met_domain="GATase_7 (E-value: 3.1e-23, bitscore:
                     73.4, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGIKEECGVFGIYDLDGGNVVPSIYYGLTSLQHRGQESCGLAVS
                     DTKGERGNVKFHKDLGLVSEVLRQDVVRKYEGDIGIGHVRYSTTGASVAENAQPLVLSY
                     VKGTLALAHNGNLVNTPELKWELIQNGAIFHTTTDSEVIAFHIARERVHSKTVEEAVLK
                     TAKKIKGAYGLVVMSPRKLIAVRDPYGLKPLCLGKRGNAYVIASESCALTSVSAEFIRD
                     IEPGEILTITKDGLKSNKELASAAAKRAHCVFEYIYFARLDSTIDGVKVYDARIRGGKS
                     LAKSYPVEADLVTGVPESGLPAAKGYSEASGIPFAFAFYKNSYIGRTFIKPTQEERESS
                     VHLKLSVLESVVKDKRIVLVDDSIVRGTTIANLIHMLKEAGAKEVHVRISSPPFLHPCY
                     FGTDVPSNDQLIAASHSTEEICKMIGADSLGYMQTDYLEGMAGGLPLCKACFDGNYPME
                     IPDYTNAEFADIVKC"
     CDS             13352..13579
                     /locus_tag="ctg23_16"
                     /transl_table=11
                     /translation="MSQSKIKLNATEEVQEFVNAASRCDFDIDVYYNRFLIDAKSILGV
                     LSLDLTRELTVDCHGESREFDRTLKKFAVA"
ORIGIN
        1 cggtatcccg ccttaattca gatgctctgg taactcagtt gccgagtaat tcacttacta
       61 tactatgctg aaggtgttcg cgaagtatat aagtttatct atatgaaatg gaataaatag
      121 tcgattttct gatactgatt gagagtaaag actctttcac gtgacgttca aaaaatcgac
      181 tttttatctt ggataattca gtggaatctc ctgcttcaat tatgaaaaca ttaagtgatg
      241 aacggagatt tactgatatt tttatagcaa ttccagaaaa taatgcaatt aagacagttc
      301 agcattttcc tgtctttcgt gctttgcagg agtgcattag ttgcattgtt ttctgggatt
      361 ataaaagaaa gataggatgg ggagttaaaa aacaaatatg gattatcagt caattgtaac
      421 atttgttatg gaaatggccg gttcagtggc gtttgctgct tccggagcga tggtgggcgt
      481 tgaacggaat atggatattt tcggcgtgag cgttctggga gttgcaacag cagtaggcgg
      541 aggaatgatc agggatattg ttctggggat catccctccg gctgtattta ccaatcctgt
      601 atatgcactg gtgtcagtgc ttgcttcctg cattgttttc tttatttttt atttcaagag
      661 agaattgctt caggggcaca ggcgtgagac ctacgataaa atcatgctgg caatggactc
      721 tgtcgggctt gggattttta cagtagtagg agtaaataca ggaatccgcc agggatatat
      781 ggacaatgtg ttcctgcttg tatttcttgg aaccattacg ggagtaggcg gcggtctgct
      841 tagagatatg atggcgagtg taccgccgta tatttttgta aaacatatct atgcctgtgc
      901 ctccatcatt ggtgcagttg tatgcgtata tatgaatcga tttgtgggaa atgtacaggc
      961 tatggtagta tcatcaattg tagtggtgct gatccgatat ctggcagcac attaccgctg
     1021 gaatctgccc aggctgtcac cacatgaata ggaaggatac cgtataaaat cagacaggta
     1081 atatttagcg cagtcaggct gagtttgtct gactgtcttt ttgttcgagg aggaaaatta
     1141 ttgataatcg gagcatctac agtttcagat tttgtggcgg tcagacggct gcgggcaaat
     1201 ttatcaggct cgcgattacc ggattctaca ccgaaatagt cagcttctgt tacatgtgcg
     1261 gcatccgcga tgctgacggt aaatgcaccg cgtgctttga tattctgtac ggttttatgg
     1321 gtctcggtaa ggttcaatgc aactgtgtca cgttcctgca tcgtacccca ggcagcgttc
     1381 attacattga tgcttccgtc ttcattatag gttgcaacca tcaatacagg cataggaaaa
     1441 atgccttctg taatatttaa tttttttctc attacaacag cccctttcag attcaattga
     1501 caggataata tatcctgcta taaatgagca agtttgaaaa aatgcacaaa attatcctgc
     1561 taatttcata aatgcttcaa aatcatcact tgcttttgca cataggaata gatactgata
     1621 cttttcctga tgaacggcac tacagattcg atgatatcca tcttgaaaag atcgatattt
     1681 gccagttcct gtgacacaaa tacaatgtgc cagtgacatc agcagccagt atctctgtat
     1741 ttcctttgag aaacggatct ggtatgtatc cagtgccaga cggtttttac attgcctgaa
     1801 aaatatctcg atcggccatc gacacacata acaggaaaag atctctttct tttatgcaaa
     1861 atcacgaact tgctcattta tagtgatata aaacaacatc aatgcatgct gaaatatgta
     1921 aaaaggcaat cgtataaaat tgcgattgcc agattttaat atttactgct ttaaggttag
     1981 gattgtatgg aaggtaccgg aatcattatc ataatacatt tgcaaatttc catggtactg
     2041 ttttacgact tttttaatgc ttttgattcc gaatccatgt ctgccattgt ctgatttatg
     2101 ggatatagga agtccctctg gattatatac aggggtattt tggcaggagt tgatgagtat
     2161 gataataaga aagggtgaat tttctttctt ttgtacggtg agctcaataa aagagtctgg
     2221 aatattctct gctgattcca ctgcattctc caataagtta cagaataaag aagtcaaatc
     2281 gcgcggatat atatgttgta ccgtgccgct tctgatgtca gtgtgaaaaa taatgtgctt
     2341 atcattgcag tggcgctgat agcggcacag aatggagttt agcatttcat gatcacagag
     2401 ttttgtggtt tcctttaagt cggaagattc catgagttgt tgtatatagt catttatttt
     2461 atcggaatca tttttttcgt tcagtaatct gattgattga agatgtttct ttatatcgtg
     2521 gatcaaaatg ctctggttct cgttttgtgc aagcatcatt tcatagtatt caacagaatc
     2581 ggattctttc tggagcagta actgcaaatc ggcatattcc tgtgatcttt ttgtgttata
     2641 ttggttgatt ccaaatacaa gtaggttgac cagcaacaga aaaacggcac agattgttac
     2701 tagaaaatca accggtgggg catatgcggt tgtttcacca atagaaagaa gagtaaacat
     2761 cataagaata gaggaaagcg ggatgaacat caagagaatt tcggagtgac cgtacggttc
     2821 ttgagctgct ttgttcccct tgaagagcca acttaacaag taaacgactg caaaaaaggt
     2881 aattttgcta aatacggtat aaaaaacaag tccgacactt gcttctaaga gaaaatgggg
     2941 aaagaatctt gatatcatcc ccaaaactgc aagttcagat attcccataa tcgctgtaag
     3001 tatagcggaa tggaagagtg ccaataataa cttgaggtta aacattatat agaggaaaac
     3061 agtgtttatc acaaaaaaac tgataatatt cagccatgtt tgcccaagca gggaaagaaa
     3121 aaacaacagt acataaagaa cacttaatag agtcagtctc tttttaccgc tatgagaagg
     3181 ggaaaaaagg ctggcggcgt actgccataa gataaccgct tctgtaaaaa aactaaaaat
     3241 aagtaaaata atatattcca tttattttca cctcatgctt tccagatata gtagatatgc
     3301 atttctgaag gaactgtatt tcctgcgtgt caggtaagcg gtaatctgag gatttgataa
     3361 atgtacggtg gagtgatcaa agtccacaat atgttcgaag ttaacaataa agctccggtg
     3421 tgtctgaaaa aaactgtttt ggggaagctt ttccaaccag taattcatat tatgaataga
     3481 gtcaaagtcc tgacgggcag tatgtacaat tacttttcgc ccctgagctt ctatggcaat
     3541 aatctgcgaa gcaggaaacg aatataccgc ctgttttgtt tccacaggaa ttttgagtgt
     3601 aatggaattg taataagcta aggcatcctt cagatttcgg aaaaaacgct gcttatctag
     3661 aggtttggaa aggtaacgga atacatgaaa acgcattgct tcatccaaat attcagaata
     3721 agaggtgaca acaaaaacga tcacatttct atttgctttt tttaattcat tcccaacata
     3781 gattccattc atgccaggca tttcgatatc cagaaaaaca atatcctttt cacctttgtc
     3841 agttaacaaa gcttcaccac tggtaaaaga aactaattca ggacatttta aatggttgga
     3901 ctcaaagtag gattcgatat acttcttcaa ttgttcaatg atcagagtgt catcatcaca
     3961 aattaaaata cgcatttttt cacctgactt tctaaataga tgtatgtgta catcttatca
     4021 catagaattt ccaaatgcaa aaaatgcgta tgaaaagaca atttaattac aattttggtt
     4081 cattatgtgt tgctttgtta tttcgtttta caagcagttc gataaagtct ccggcaagct
     4141 ctatgtcgga ttgattacat aaccgtagtt tatcaataat atcctgtgga atattataag
     4201 cgtgcatact gccgagcaga aggtagtcag gtgtaacatt gagtaaatta caaatctgaa
     4261 tgaaaatatc cagacttggt ttttgccttc cgttttcgat tgatgacata tggctattgg
     4321 atatatttaa tctttcggca agttctgcct gttttatccg taattctttt ctgcgtattt
     4381 tgatgcggtt tcccatacct tcatattgaa attctattta tcccaccttc tttcagtaga
     4441 attttaccaa tagaactaaa taaaaagaag aatgtaacaa agaactattc tgcaatatat
     4501 taaacaaact gatatttata tataaataat tctgtatcac atattatttt tcgtagaaaa
     4561 gagggaaatt atccaatatt gtaaagaatc attccgttca ttccaaaggg gtcgtttatt
     4621 tgattaaagt ggtatatgat tgcttatgtg aaaatcaatg acaaatttta gtggaaagga
     4681 gagaggtcat tatgaagaaa gaggtaacta aatcggttgc aaaaggaatg aaagcagcat
     4741 tagatgttgt gttacggaca gaagctaaca cagcttcttg tcttatcatg tatcagccta
     4801 aggcaccgaa agaattaatg aactacagga gaaacaagta atggaaaaat gtacagatac
     4861 agtagtaaat tggatgatcc ggtgtaatgc gataaacgag gcggataagg aactttacaa
     4921 gtatgcatta tatagttttt ttctattggt atcaccactt atccttgcag gagttattgg
     4981 ctttggcttg ggaagcgtaa aacacggagt tgctcttatt tttccgtttg tggttctgag
     5041 aaaatttagt ggtggttatc atgcaaaaaa tttgcacact tgtattcttg gatctggttt
     5101 tctattgttt ctgtgcataa tgttatcaat gcatgtgcaa tgtgatttga agttggcaat
     5161 agctacagtt attgcgtctg tgagcctgat tacatttagt ccaatagaca gtgaaaacag
     5221 aagacttgat actaacgaga aaaggacata taaaaaaaca acagtgttct tcgtgatact
     5281 gtttgggctg ttagatatag ctttattttt gctgggaaag tacatctata caatctgttt
     5341 ttctgttggg atattactga cagcaggctt acaagtacct tgtatcgtaa agaaaatgtg
     5401 taaatcgacc aaaaacagac tgtaaatgtc gtttggtgca aaaggggttg aaatcatggc
     5461 aaaaataaag ataataaagt ttgtcattga tttgatcaaa gttctttatt tacagttaat
     5521 tcagtttgtt cattgaaagg gagtggattc caatgggaca atgatagaat tctatcactt
     5581 taaattgagt agttcggttc ggagtagtta aacgggcata atggaggtaa aagattaaaa
     5641 tgacacataa gaaagaagtt gtttttagct tgttgtttgt aataatggtg ttatgtacag
     5701 gctgcagtga taaagataat ggagatacgt ctaaaaataa caggacttca ggagaatcat
     5761 ttgttcaaga agaaactatt gagagtacag acaatacaga caatgcagac ggcagctcgg
     5821 caccaacgcc agaactgaaa acgccccgaa cgaaaaagga attggaagat gcgcttggta
     5881 cagtgaatga gtcgggaaaa tggacgccac cagccggttc tcatatagat cccaaaacag
     5941 gtaatatact gaataaagat ggggtcgtgg ttggaactac gcaggaacct tatagtaaag
     6001 cacgtccagg ttctcaagga tgatgatatg gtgtaaaaaa attatgggag gaaaagatta
     6061 tgaagtatat gagaaaaaac tcatttgtag tgtgtttggt cataagtgca attcttttga
     6121 caagttcatt tgcaatgccg gtgcttgctg cggaaaatac aggaattgaa acaagctctg
     6181 tcacgagaag cgtaccggga tattacaagt gcacagggtc ggatgtaaat atcagatcag
     6241 gccctggaac acaatataca atagtaggca cattgaatta tggcacaaaa gtatatgtat
     6301 attctatcag taatgggtgg gccaaaattt ctcttggcgg catttaccgt tatgttagtg
     6361 ccgattacct tcgggagctt taaggaaaaa catttaatat aaacgaggca taggtaaata
     6421 gctgtatggg ctgccgcact gaaaagtttg gtgcggcagc acttttgttt acttttttaa
     6481 ttgaaactac aaatggacaa attctaaaaa acgtcccaaa aacagtattc tgtgtttggg
     6541 ttataaagac aaatttaaaa tatatagata tttccggtgg ttcgtggtat gataaaaata
     6601 gaaacaaaag tgctatttca agaaagggtg atggttatgg cattggcaca ggcaacaaaa
     6661 tcccatgaac caacttatac aatcaatgat gcaatggatg ttcttttgtc aaggctggat
     6721 gaagccattg atgatatgga aagtgacaga gtgcagatag tggaagaagc atgggcagaa
     6781 attgatgcaa tataaggggt acggatggaa aaaagaaaat acaaagttgt aattgcccag
     6841 agcggcaagc tggatgtgaa ggaaaaaaga aatatatcct tcagcaattt aaataccggg
     6901 agtatgcaga ggatttttcc caaaagatta aaaagcggtt cttgcacttg acacacttcc
     6961 taccagatat aatacaatag gcttccgata tcgtggctat gatatttaca tgaaatatac
     7021 tgcctgtttt ttaacgccat tggaattgtt agaaagaaag attaaaataa gagacaccag
     7081 caatcaatac gctgatgtct cttattaata ttacctgatt gttgataaat aatttacttt
     7141 gtatcctgca gtgcgagata accttcttcg cctgtacgga tcttaacgac attttcaatg
     7201 tcatatacaa atactttacc atcaccaatc tgaccggtat ggaggactgc cttggcagtt
     7261 tcgataactt tctgtacagg tacgagactt acaacaatct caattttgac cttaggaaga
     7321 agattcattt ccatctcaac accacgatag taggatggag cacctttctg tacaccgcat
     7381 ccgagaacgt tcgtaatagt gatacctgta acaccgatct cattcattgc ctgcataaat
     7441 tcatcaagct tattctgacg ggtgatgata acaacttttg taagcttatg aacgccttct
     7501 ttcggaagtt caggaactga ttcagcagga gcagaaggtc tggctgtgac aacaggagct
     7561 tttatggaag ttcccatagg agtcggaaca ccagccattg cgaaaccgtc ataagcactt
     7621 gcaagaccat gttctttgga gtcaagacct gcgatctctt cttcagctga aacacgaagt
     7681 ccgattgtat gtttgattac ctggaagata attgtcatag taacaacaac ccatgcgatt
     7741 gtgatgatca taccagtgaa ctgaacacca aatccgtgga agccgccgcc tgtaaggagt
     7801 cctttccagt ctgtgcctga tccgtctgag aaaagaccaa ctgcaagggt accgaaagca
     7861 ccgtttaaac catgaacacc gacagcacca acagggtcat caattttcag aaccttgtca
     7921 ataaattcaa taccaaatac tacgataaaa ccggaagcaa taccgatgat tgctgcggat
     7981 gtaggagaaa ctgtgtcgca tcctgctgta attgctacaa gtcctgcaag agaaccgttc
     8041 agagacatgg aaacatccgg ttttttgtaa cgtacccatg tgatgatcat aacagttaca
     8101 gttgcaacag ctgctgaaag gttagtagta acgaagattt taccggcact tacgattgca
     8161 tcgccttcca tacttactgt ggaagcaccg ttaaatccga accagcagaa ccagaggata
     8221 aatacaccta aagcgccaac tgtaaggttg tgtcccggga tagcctttga tttgccgtcc
     8281 tttgtatatt taccgatacg aggtccaagg atgatggcac cgatcagagc tgccacacca
     8341 cctaccatat gtactgcaca ggaacctgcg aaatcgtgga atcccatctg gctgataaat
     8401 ccaccgcccc agatccagtg tccggatacc ggatatacaa caagactgat cataaggctg
     8461 tagatgcaat aggaaaggaa cttggtacgt tctgccattg caccggaaac aattgttgcg
     8521 gatgttgcac agaatactgt ctggaagatt aagaatgccc agaaaggaac tccgtcagga
     8581 agcattcctg aaccatagtg tgcttctgtg gcaataccac cgatctttcc gataaatcca
     8641 ttacctgcac caaacatcag accgaagccg accagccaga agaccggggt tccgatacag
     8701 aagtccatca ggtttttcat aataatgtta cctgcgtttt tggctcgtgt gaagcctgtt
     8761 tctaccattg cgaatccggc ctgcataaag aagaccagcg cggcgccgac cagcacccat
     8821 attgtgttta ctgcggaaaa ttccataata atattcctcc ctcataaaaa tttcctcata
     8881 ttttataaaa tgcaaaaagc gcgatgcctg gaaatgtagc cagttcatcg cgcttttgcg
     8941 aatataaaat ccatatttat agtgtattgc ataactgatg taatagaaaa gacatttcgt
     9001 atgactgtat gcaatgcagt ttaaaatcaa aattatatgt aaaacaggag aacatcaaaa
     9061 tatcgtgtga ttaatggatg aggaaatcga taatgaatta tgaagtagag ttcataaaga
     9121 tattcccctg ttattacctg ttaattaaac ggaaaacaga agcttgtcat atgtaggata
     9181 tggaagcagt gcatccggaa tcagagtttc tgctgcatct acagactttc tgagttcatc
     9241 catatcagaa agaacaactg tctggtatgc ttttgcatta gccagaggat cttctgtagc
     9301 aagcgctttg gcagtgtctg cttttaaggt ctcaagacct gtggaaatct catcagcaag
     9361 ctgtgacagc tctttgatca gttttccttc agaagctgtg ctgacatctg aaacaactga
     9421 ttttttagca acagcagtag ctgcaacttt gtcgatatat gcgaatacag atggaaggaa
     9481 atccttctgt accatttcaa ccatagtatt ggactcaatg ttaagaatct tggaatagga
     9541 ttccagccag atctcataac gggattcaat ttcttctttt gtgaagatat gatatttggt
     9601 aaagagttca atatttttat ctgcgatcca ctgaggaaga gcatctggtg tagatttcag
     9661 gttaaagaga cctcgtttct cagcttcttc gatccattcg tctgtataac cgtttccgtt
     9721 aaagataaca catttatgat caataattgt cttcttgatc agttcgtgga ttgcatcctc
     9781 catcttgtct tccggtacat cctttaactg ttctgcaaac tggtgaacac actcagcaac
     9841 agcagtgttt aaaataatgt tcgggtttgc aacagaagct tcggaaccaa gcatacggaa
     9901 ttcgaatttg ttacctgtaa atgcgaatgg tgaagtacgg tttctgtctg tattgtcttt
     9961 tacgaaatgt ggaagtactt ttgcaccgat atccatctgg actgcgcggc ttcctgcaaa
    10021 atattcgtca ttttcgatag attttaatac ttctgtcagt tcatcaccga ggaatacgga
    10081 tacaacagca ggcggagcct cgtttgcacc aagacggtga tcatttcctg cacttgctac
    10141 agaaatacga agtacatctg cgtattcatc aactgctttg ataacagctg tcaggaaaat
    10201 caggaactgt gtattttcag caggtgtttt tcccggatca aggatattta caccggtatc
    10261 tgtaatcata gaccagttgt tgtgtttacc acttccgttg attccctcaa atggtttctc
    10321 gtgaagaagg catacaagtc cgtgcttgtc ggcaactttc ttcattactt ccattgttaa
    10381 ctggttgtgg tcaaccgcaa cgtttgttgt atcgaataca ggagccagct catgctgtgc
    10441 aggagcaact tcgttatgtt ttgttttggc aggaatacca agtttccaga gctctacatc
    10501 caggtcatgc atataagctg cgacacgagg tttcagagca ccgaagtaat gatcttccat
    10561 ttcctggccc ttaggagcag gagcaccgat cagtgtacgt ccgcagaata caaggtcttt
    10621 tctctgtttg tataattcct tgtctaccag gaagtattcc tgttcaggac ctacagttgt
    10681 atttacgtgt ttgatatctt tatttcctat tatatggaga aggtttgtag cttctttatc
    10741 aagtgtctgc atggaacgaa ggagaggagt ctttttatca agagcttctc cgctgtagga
    10801 gcagaatgct gtaggaatgt aaagggttcc gtctttgatg aatgccggtg atgtcggatc
    10861 ccatgctgta tatcctcttg cctcgaatgt ggcacgaaga ccgcctgacg ggaaactgga
    10921 agcatccggc tcacctttta caagttcttt acctgagaaa tccatgatca cctgaccatc
    10981 tcctgtagga gaaatgaagc tgtcatgttt ctctgcagtt acgtttgtca ttggctggaa
    11041 ccagtgagta taatgagtgg cgccgttctc ggtagcccat tctttcattg caacagcaac
    11101 ggagttggca acatcaagtt caaggtgtgt accgctctcg attgttttct ttaatgcttt
    11161 gtacatgtct tttggcagtt tacttctcat tactttgtcg ttgaagacca ggctgccgta
    11221 cagttcaggg atattctgtg ccatataggt actctccttt cggtttgcaa tattttctga
    11281 atatgtgtag tgccgctgca gatcaccatt gtgactgcct gcggttttcg tctcatagaa
    11341 aattcctcat cgaacatttt ctatgaaacg aaagttttat aaaacgaaaa aagcgccctg
    11401 gatgagatct ctgtagatct ttccaaagcg cctttgcttt atgtgctgta ctataaacga
    11461 aatgaaaaca gatgtcaagc actttttttg aaaaaattca gaaaaaattt ttgagatatg
    11521 gcaaaaaaag gataggttga caaatttgtt tctattatta taatttgatt ttggaacccg
    11581 tcaaacataa gaaaacaatg tcagcgggtt ttgaaagtaa agttaaagtc agacaagaga
    11641 atacgatcgg aggaaatcag atggctggaa taaaagaaga gtgcggcgtc tttggaattt
    11701 atgatctgga tggcggcaat gtagttccgt ccatatatta tggactgact tccctgcagc
    11761 acagaggaca ggaatcctgc ggacttgcag tttctgatac taagggagag cgtggaaatg
    11821 tgaagtttca taaggatctg ggacttgtaa gtgaggttct cagacaggat gttgtccgta
    11881 aatatgaggg agatattggt attggtcatg taagatattc cacaacagga gcttctgttg
    11941 cagagaatgc acagcccctt gttttgtctt atgtaaaggg aactcttgca cttgcacata
    12001 acggaaatct ggttaataca ccggaactga aatgggaact gatccagaat ggagcgattt
    12061 tccatacaac tacagattca gaggttattg cgttccatat cgcaagagaa cgtgtgcatt
    12121 ctaaaacagt agaagaggca gtgctaaaga ctgcaaagaa gatcaaaggt gcatatggtc
    12181 tggtagttat gagcccgaga aaactgatcg cagtccgcga cccatatgga ctgaaaccat
    12241 tgtgtctcgg taaaagagga aatgcttatg ttattgcttc tgagagctgt gctctgacat
    12301 ctgtaagtgc ggaatttatc cgtgacattg agccgggtga gattcttacg atcacaaaag
    12361 acggactgaa gtcaaataaa gagcttgcgt ctgctgctgc aaaacgcgcg cattgtgtgt
    12421 ttgagtatat atattttgca agacttgaca gtaccattga tggggtgaag gtctatgatg
    12481 ccagaatccg cggtggtaaa tctcttgcca agtcttatcc tgtagaggca gatcttgtaa
    12541 caggtgtacc ggagtccgga ctccctgctg caaagggata ctccgaagca tcaggaatcc
    12601 cgtttgcatt tgcgttctat aaaaacagct atattggaag aacatttatc aaaccgactc
    12661 aggaagaacg tgagtccagc gttcatctga aactgagtgt gctggaatct gttgtaaaag
    12721 ataagaggat tgttctggtg gatgattcta ttgttcgtgg aacaaccatt gcaaacctga
    12781 tccacatgtt aaaagaggcg ggagcaaagg aagtgcacgt acgtatcagt tcaccgccat
    12841 ttttacatcc atgttatttc ggaacggatg tgccgtcaaa tgatcagctc attgcagcca
    12901 gccacagcac ggaggaaatc tgtaaaatga tcggagcaga ttctcttggc tacatgcaga
    12961 cagattatct ggaaggaatg gcgggcggcc tgcccttatg taaggcatgc ttcgatggaa
    13021 attatccgat ggagattccg gattatacaa atgcggagtt tgcagatatt gtgaagtgtt
    13081 aagtcgcaaa aattcataaa aaatgcagaa acctgtcgat gatatatgga atcaatctca
    13141 cataatggta aaaccaatat aggatgaagt catacataat gtataaaata atgctgtgaa
    13201 aacatatata aacgaacaaa atgcacaata gaacccctgc gctttatgaa aattggataa
    13261 atttaaaaac ttgacaaatt ctgaaatgtg gaacataata tgggcgtctg atagaaaaaa
    13321 acaaagaatg ttttcagaaa gggtgatcac gatgtcacag agtaaaatca agttaaatgc
    13381 aaccgaagag gtgcaggaat ttgtgaatgc tgcaagcaga tgtgattttg atattgatgt
    13441 ttattacaac agatttttaa ttgatgccaa atcaatcctt ggtgtactta gtctggatct
    13501 gaccagagaa ctgacagtag actgccacgg ggagagccgg gaatttgatc gtacattgaa
    13561 gaaatttgca gttgcataaa ttttacattt ttataaccga ataattatcg cagagaagac
    13621 gggtctggaa gatgaacttc tacagattcg ttttttctgt attatgactg tgttcagagt
    13681 aattccataa aatataactg cttcatagtt tatcagaagg aacttatttg atttgttttt
    13741 gcttaaaaac gggaaattca ttattgacaa acgaaaaaaa atgttttata gtatagcata
    13801 tttttaaaga aagccaattg aacatattat tatagaagat atgatgatct gacaaaggcg
    13861 tcagatgcag aataccagat gggtcaagtg ccctctgata gctgcatctg acgctttttt
    13921 attaacaaag gatgatggag gaggaaatca aaatggcagt gaaatacgta tttgttacag
    13981 gaggagttgt ttccggtctt ggaaagggaa tcacagctgc atctctgggg cgtcttctga
    14041 aagcgagagg atatcaggta accatgcaga agtttgatcc ttatatcaat atcgaccccg
    14101 gaaccatgaa cccgattcag cacggagaag tttttgtaac agacgatggt acagagacag
    14161 acctggatct gggacattat gagagattca ttgatgagag tcttgataaa aattccaatg
    14221 tgacaaccgg taaggtttac tggtctgttc ttcagaaaga acgtcacggg gatttcggcg
    14281 ggggtaccgt acaggtaatt cctcatatta caaatgagat taagagtcgt ttctaccgcg
    14341 ccaaatcacc ggaggaaaac aagattgcca ttatcgaggt gggaggaaca gttggtgata
    14401 ttgaaagcca accgttcctg gaagcaattc gtcagttcca gctcaatgtg ggacatgaca
    14461 atgcaatcct gattcacgta acattaattc cttatttaaa ggcatctgaa gaactgaaaa
    14521 caaaacctac acaggcaagc gtaaaggaac ttcagggaat gggaattcag ccggatgtac
    14581 tggtgtgcag aagtgaacat gagctgacag aggacattaa agaaaaaatc gctttattct
    14641 gcaacgtacc tgtatcacat gtacttcaga acctggatgt ggaatattta tatgaagctc
    14701 ctcttgcaat ggaaagagag aagcttgcag atgtagttct ttcaagtctc cgtctggaaa
    14761 acagaaaacc ggatttaagt gactgggagg aaatggtaga aagtctgaga aatccgaata
    14821 aaacagtaaa gatcgcaatt gtaggaaaat atacacagct tcatgatgca tatctcagtg
    14881 tagtagaggc actgaaacat ggcggaattt cctgcagagc caaggtagaa cttgactgga
    14941 tcgattccga agaactgaca gagaagaatc tggatcagca gcttcacaat gtagatggta
    15001 tcctggttcc gggtggtttc gggaacagag gtacagaagg aatgatcctg gcagcacagt
    15061 atgcaagagt acataagatt ccatatcttg gaatctgtct gggaatgcag atggcaattg
    15121 tagaattcgc ccgtcatgta cttggatacg aagatgcaaa cagtattgaa ctgaatccgg
    15181 agacaaagca tccggtaatt gcattaatgc cggatcagga agatatcgaa gatatcggtg
    15241 gaaccttaag acttggaagt tatccatgta ttcttgcaga aggttccaga tcctatgaac
    15301 tctttggcaa aaaagaaatc catgagcgcc acagacatcg ttatgaagta aacaatgcat
    15361 tccgtaaaga acttcaggag aaaggaatga atatcgtagg aacttcccct gataatcata
    15421 ttgta
//
