LOCUS       c00050_gnlPro..        13232 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OEADKHHE_50.
ACCESSION   c00050_gnlPro..
VERSION     c00050_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:19:22
            Original ID  :: gnl|Prokka|OEADKHHE_50
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2701
            Orig. end    :: 15933
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13232
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[12701:15645]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12944
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..13232
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13232
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(2369..3532)
                     /locus_tag="ctg50_3"
                     /transl_table=11
                     /translation="MILRLERCGMKFAHIGDLHIGKRVHDFSMLEDQRYILDQMMKIFA
                     EQKVDGVLIAGDVYDKTVPSAEAVQLFDEFITGLAKAEIPVYMISGNHDSAERLSFGAK
                     LFESSDIYISQVYDGEMKRIVLKDQYGPISVYLLPFLKPAAVRHALQRDDINTYEEGVM
                     AALQECEIDTTQRNVLVAHQFVTGADRSDSEETWVGGLDNVSAEVFKDFDYVALGHIHR
                     PQKMGRETLRYSGTPLKYSFSEADHKKSVTIVELLEKGNVRVSTVPLIPRRDMRKLRGT
                     YMDVTAKDHYTAENKMDYLQITLTDEEDVPGALQKLRTVYPNLMRLEYDNKRTRENREV
                     QAVEVQEQKSELELFEEFYELLNNEPMKEEQTEFVEKLIQDLKEVRV"
     CDS             complement(3573..4316)
                     /locus_tag="ctg50_4"
                     /transl_table=11
                     /translation="MLTEQRFDIILKLLEEKKSVTVTELRELLDASESTVRRDITALDK
                     AGKLTKVFGGAVALNHKVTAYEPTVAQKSELNKEEKQKIAKYAASLITPDDFVYLDAGT
                     TTGLMLEYLAGVRAAFVTNAVSHAQTLAKMGIRVYLIGGELKSSTEAVVGSQAMQMIQM
                     YHFTKGFFGTNGITRREGFTTPDTSEAIVKSTAMKQCKDVYILTDKSKFGEVSSVTFGG
                     FTDAKILTEEIPEEYQDSKNILKVK"
     CDS             complement(4611..4868)
                     /locus_tag="ctg50_5"
                     /transl_table=11
                     /translation="MKEFKYVVTDNEGIHARPAGELVKLVKGFESTISIEKEGKKVDCR
                     KLLALMGLGVKKGHEVTFTIEGADEEAAYEAVSKFMQDNL"
     CDS             complement(4928..6841)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTS_EIIC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_6"
                     /sec_met_domain="PTS_EIIC (E-value: 1.5e-21, bitscore:
                     66.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRITDLLDRRSVSLTAAPKTKSETLDMAVDLMVKSEKISDREAYR
                     KQVYLREEESTTGIGEGIAIPHGKCDAVKKPGLAAMVIKNGVEFEALDDEPVTLLFLIA
                     APNTEDNIHLDVLSKLSVMLMDEEFTESLRNASSVDEFMDIIDRADSEKKDIDERLADT
                     GSAEGTQAKILAVTSCPTGIAHTYMAAEGIEKAAKAKNCFVKIETRGSGGAKNVLTDQE
                     IADADCIIVAADAKVPMERFDGKKVIECQVSDGISKADQLIDRAINGDAPVYHAAAGSQ
                     TSSAGNKSGGSVGHKIYMQLMNGVSHMLPLVVGGGILIAIAFLIDGLSVDLSALPADQR
                     ANFGTITPVAALFKGIGNTAFGFMLPILAGFIAMAIGDRPALALGLVGGMMAANGKSGF
                     LGALLAGFAAGYIILGLRKLCDKLPEALEKIAPVLIYPVVGILIIGLLMTFIVEPVMGG
                     INTGLNNALTGMGSSSKVILGIVLGGMMAIDMGGPFNKAAYVFGTAAIAAGNYDIMAAV
                     MIGGMTPPCAIALATLLFKDKFTKEERDAGPTNFIMGLAFITEGAIPFAASDPLRVLPS
                     CIVGSAVAGAISMAFDCTLMAPHGGIFVFPVVGNAVMYLVALVVGTVISAVLLGLLKKK
                     AA"
     CDS             complement(6859..7770)
                     /locus_tag="ctg50_7"
                     /transl_table=11
                     /translation="MIYTVTFNPSLDYIVSVDDFKLGLTNRTSSELMLPGGKGINVSTV
                     LMNLGIENTALGFTAGFVGKEIIRRLHEMGVKSEFIQISEGVSRINLKLKSIDGTEING
                     AGPVISKDKVEELMKKLEELGEGDVLFLAGSIPSSMPDDMYEQIMARLDGKGVMIVVDA
                     TKDLLVNVLKYHPFLVKPNNHELGEIFGVELKTRKDVIPYGKKLQEKGARNVLISMAGE
                     GAVLVAEDGQVFEEPAPKGRLVNGVGAGDSMVAGFVAGWMEKKDYEHAFHMGIAAGSAS
                     AFSENLATKEEIEAVYRQITEK"
     CDS             complement(8082..9497)
                     /locus_tag="ctg50_8"
                     /transl_table=11
                     /translation="MWEAINSFLTTVDNLVWGVPLMVLIMAGGILLTARLGLLQMRRLP
                     LALKWMFKNEEEGDGEISSFAALCTALSATIGTGNIVGVATAVCAGGPGALFWMILAAF
                     FGMATKFSEGLLAVKYRVVAEDGHSLGGPFYYIEKGMGTKWKWLAKIFAFFGVCVGLFG
                     IGTFSQVNGISSAVQNFFDPNKSNCVNIPFLGEYSWAVVISSLILAACVAAILIGGLKR
                     IATVSQIIVPFMAVIYLIFSVALILLNITEIPAAIVTVVKGAFNPSAVTGGVVGTMIVS
                     MQKGVARGIFSNEAGLGSAPIAAAAAQTKEPVRQGLVSMTGTFIDTIVICTMTGLSIVL
                     TGAWQVEGLEGVQVTTYAFQHGLPIPGQISAFVLMICLVFFAFTTILGWDYYSERCLEY
                     LTNGHKKTILTYRWLYILAVFIGPYMTVSAVWTIADIFNGLMAIPNMIALFALSGVIVK
                     ETKAFFAAEKHKM"
     CDS             complement(10001..11680)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_9"
                     /sec_met_domain="HGD-D (E-value: 1.3e-17, bitscore: 53.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 9.6e-66, bitscore:
                     211.3, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPEGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKSHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDEKGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADV"
     CDS             complement(11673..12944)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_10"
                     /sec_met_domain="HGD-D (E-value: 2.3e-56, bitscore: 181.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWEAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLWPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERAFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
ORIGIN
        1 atctggtctg tgatcgttgt aagttctgtc tgagtcttac caatctgcat ctccagaagt
       61 tttctctgtt ccagaagtgc tgtcagatcc ttttgtttct gttccagaat atcctgctgc
      121 tgttttagcc attctgccgc tttctttccc tgcagcaaaa cctgtgatac attaccagtt
      181 tccttttgat acactgtttc actgctatga tcctgtaaca gttccggatc agttttcatc
      241 ctctgtcttg catcttcttc atagatccat gaaagtacag gttccttcaa ttggttattc
      301 agctgttcct gaatgctctc cagctggctc ttcctctttt caagactgat ctgtaatttc
      361 tgaaattctt ttgcatgctg ctccgactgt gtggtgaact cttccttttt cttcaacaga
      421 tcctgataaa cttttttctg tttttggatt tcttctaatc ctgtctgtac gctgctttcc
      481 tgatttttta taaataaaca taattcatga tcagaaagtt catttcgaag tatttcttgt
      541 gtttcctctt gtggcagaaa ctgtgctgca tagcttttaa acccttctgt caattcttcc
      601 ctgcaacgct gcagcagtcc tgctgcctct cctgcctgca cacttgcgtc agatgccgct
      661 ttttccgcag cttctgttaa ctttttctgt tttttcagtt gttcttctgt gggaacttcc
      721 ttcggagtct gcgtaagctt tggatgatga acagaaccac ataccggaca cggcattcca
      781 tcctgaagtc ctgctgccaa tatccccgcc tgcccatcca gataagcctg ttccattttg
      841 ttcaggattt cttttatttc tgcccgtttc tgagaagcgg tcagataagc cttctttttg
      901 ctttctgctt tcttttccag atcctgatac cgtttctgct gatcttctat tttctgtatc
      961 tgctgcaaac atacgaccag gctgttctct ttgatttcca aattcccacc ggaaacaatt
     1021 ttctcttcca gatcagtcaa atcctttttt atctgtttcg caagttgttc ttcctgtccg
     1081 gactgtattt tcagttcact gatttttgtc tgaagaaact caagatttcc gcagttctta
     1141 taaactcctg cataaagagt atctattttc tctttccgga aatctgtttc tgctttttct
     1201 ttctccgcac tgtctgttgt ctgatattct ttttgttttt gttcaagaac agttttcttt
     1261 tctttctgac gattctgcag tgcaatactg tctattgcca atttttcaat ctgttttgaa
     1321 acattttcta tttctctgcg cagattttcc agatttgtat aacgcttcag attctctttt
     1381 tctttctgta tggaaagtat caggcgttgg atctcctctg gttcctttgc cccattttct
     1441 gcatcttttt gtgcctgttc caactgtgga agcaatcctt ctctctcttg cagaagctgt
     1501 tccttccttg cctttgcatc tgcttcttta tgagcctttc ccaaaagctg atttactttt
     1561 tcaagttctg tatcattctc tttgatctgc ttatttacag ctttcaagtt atccttatct
     1621 gccttcagaa actgctccag aatttccaga ctctcttcca gatttccttc aaagccattc
     1681 ttctccatca atatccactg ttgtcccagc tgatcttctg tagaatatct gacctgttcc
     1741 gtatactggc ggatacttct caacagctct ttatacgcct tgtccagacc accggcctcg
     1801 aattttaatt tttcctgaat caccttataa atatccgtat ggaaaagctt tctgaaaatg
     1861 ttgctgcgtt cctctgtatc agccagcagc aatttcctga aatctccctg tgcgatcata
     1921 gcgatctgcg taaactgctt catatccagt ccgatcagtt cagtaaccgc ctggttcact
     1981 tcctttagct ttgtcacagg agctcttcca tcagaaaaag taagcaacgc ctcccccttt
     2041 tgggtagtca ttccagtgcc tctggtcttt ggccgctcat aatccgggct tcgcttcact
     2101 gtatacactg catctttata ttcaaaaata tattccgcat acgtaggtgt ttccggtttt
     2161 gcatacttac ttctgagcat ggatgcctcc cggactcctc cgcttgtctc cccatacaac
     2221 gcaaatgtaa tcccatcaaa gatcgtcgtt tttcccgctc ccgtatctcc ggtcaccaga
     2281 aaaaggccct gtcctccaag ctgtgtaaaa tcgatcacag tctcatccgc atatggacca
     2341 aatgcagata atgtcaactt caatggtttc atacgcgcac ctccttcaga tcctggatca
     2401 gtttttccac aaactctgtc tgctcttctt tcataggttc attatttaac agctcataaa
     2461 actcctcaaa cagctccagt tctgactttt gttcctgaac ctccactgcc tgaacctccc
     2521 ggttctcacg tgttcgttta ttgtcatatt ccagacgcat cagattggga taaacagtac
     2581 gcagcttctg gagtgccccc ggcacatctt cctcatctgt cagagtaatc tgaagataat
     2641 ccatcttatt ttcagcagta taatgatcct tcgctgtcac atccatatag gttcccctca
     2701 gcttacgcat atcccgtctg ggaatcaaag gtactgtact gaccctcaca tttcccttct
     2761 ccagaagctc cacaatcgtt accgactttt tatgatctgc ttccgaaaaa gaatacttaa
     2821 gcggcgtccc actgtaacgc aaggtctctc tccccatttt ctgaggtctg tggatgtgtc
     2881 ccagtgccac atagtcaaaa tccttaaata cttccgcact gacattgtca agaccgccaa
     2941 cccatgtttc ttctgagtca cttctgtctg ctccggtcac aaactgatgt gccaccagca
     3001 catttctctg tgtcgtatcg atctcacact cctgcagagc agccataaca ccctcttcat
     3061 aagtattaat gtcatccctc tgcaaagcat ggcgtactgc cgcaggtttc aaaaaaggca
     3121 gaagatatac agatattggt ccatactgat cttttaacac aatccttttc atctctccat
     3181 cataaacctg cgaaatataa atatcactgc tttcaaacag ctttgcccca aaggaaagcc
     3241 tttctgctga atcatgattt ccactgatca tgtacacagg aatctcagct ttagccagtc
     3301 ctgtaataaa ctcatcaaac aactgcactg cctctgccga cggcactgtc ttatcataaa
     3361 catcccctgc gattaaaact ccatccactt tctgttccgc aaagattttc atcatctgat
     3421 ccagaatata cctctgatcc tccagcatgg aaaaatcatg cacccttttt ccaatatgca
     3481 aatccccaat atgcgcaaac ttcatcccac atctctccaa tcttaatatc attcctgcct
     3541 gctctgtctg ccggcggcat actgtcaatt atttatttca ctttcagaat atttttgcta
     3601 tcctgatact cctccggaat ttcttctgta agaattttag catctgtaaa cccgccgaat
     3661 gtcacagaac ttacttcgcc aaactttgac ttatctgtca gaatatatac atctttgcac
     3721 tgcttcattg cagtactctt tacaattgct tcgctggtat ccggtgtggt gaagccttct
     3781 cttctggtga ttccatttgt tccgaaaaat ccctttgtaa aatgatacat ctggatcatc
     3841 tgcattgcct gactgcctac gactgcttct gtggaactct tcagttctcc tccgatcaaa
     3901 taaacccgga ttcccatctt tgccagagtc tgggcgtggg atactgcatt ggtgacaaag
     3961 gcagctctta cacctgccag atattccagc atcaggccag tggtggttcc tgcgtccaga
     4021 taaacaaaat catccggtgt gatcaggctg gctgcatatt ttgcgatctt ttgcttttct
     4081 tctttattta attctgattt ctgcgctact gtcggttcat aggcagttac tttatgattt
     4141 aatgctactg caccgccgaa aaccttggta agttttcctg ctttgtccaa tgcagtaatg
     4201 tctctgcgca ctgtggactc tgatgcatcc agaagttctc tcagttctgt tactgtaaca
     4261 ctcttttttt cttccagaag cttcagaata atatcaaatc tctgttctgt aagcatgtac
     4321 ccctgcctcc attgtatatt tgctttgatt gtttacttct gattattttc tccgatatct
     4381 acgaattgct ccgctgcttc gtagctcccg caattctaca aacattcgga atccgcagat
     4441 ttacttcgta aatcgctact tcctcatgtt tggcgggtcc caagttcaaa agtcttatcg
     4501 tgcaagcacg aacgactttc tgccttttga ccctgatatt tcattataac agaaacagga
     4561 gatgaatgca tcatctcctg tctgtcagtt tcttatttta ttccgtaaat ttacaggttg
     4621 tcctgcatga atttgctcac tgcttcatat gctgcttctt catcagcgcc ttcaattgtg
     4681 aatgttactt catgaccttt cttaacgcca agtcccatca gtgcaagaag ttttctgcag
     4741 tctacttttt taccttcttt ttcaatagag attgttgact caaatccctt taccagtttt
     4801 acaagttctc ctgcaggacg tgcgtggatt ccttcgttgt ctgtaactac atacttaaat
     4861 tctttcattt tgatatcctc catgttcttt attttaattt tttgttattg cttttttatt
     4921 tcactgctta tgctgctttt ttctttaaca ggccaagcag aactgcagag attactgttc
     4981 ccacaaccaa tgcaaccaga tacataactg catttccaac tacagggaat acaaaaattc
     5041 caccgtgtgg tgccatcaat gtacagtcaa acgccatgga aatcgctcct gccaccgcag
     5101 atcctacgat acaggaagga agtacacgaa gggggtcaga tgctgcgaat ggaatcgcac
     5161 cttctgtgat aaatgcaaga cccatgataa agttggtagg acctgcatct ctctcttctt
     5221 ttgtgaactt atccttaaat agcagtgttg ccagtgcaat tgcacaggga ggtgtcatac
     5281 cgccgatcat aactgctgcc ataatatcat agttacctgc tgcaattgca gctgttccga
     5341 atacatatgc tgctttgttg aacggaccac ccatatcaat agccatcatt ccgccaagca
     5401 caataccaag tattacttta ctagaacttc ccattcctgt caaggcatta ttcagacctg
     5461 tgttgatacc gcccataacc ggctctacaa taaatgtcat caggagtcct ataataagga
     5521 ttccaactac aggatagatc aaaacagggg cgatcttttc cagggcttcc ggaagtttat
     5581 cacataattt acgaagtcca agaataatat atccggctgc aaagcctgca agcaaagctc
     5641 caaggaaacc agatttacca ttggctgcca tcataccgcc taccagacca agtgcaagtg
     5701 ccggtctgtc accgattgcc attgcaataa atccggcaag gatcggaagc atgaatccga
     5761 atgctgtatt accgattcct ttaaacagag ctgctaccgg agtaatggta ccgaagtttg
     5821 ctctctgatc tgccggaagt gcacttaaat ctacacttaa tccatcgatc aggaatgcaa
     5881 tggcgatcag gataccgccg cctacaacta atggaagcat atgagatacg ccattcatca
     5941 gctgcatata gatcttatgt cctacactgc cgccggattt attaccggca gaagatgtct
     6001 gggaacctgc tgctgcgtgg taaaccggtg catccccgtt gattgccctg tcaatgagct
     6061 ggtctgcctt actgattccg tcggatacct gacattcgat cactttttta ccatcgaaac
     6121 gttccattgg aaccttggca tctgctgcga caataataca gtctgcatca gcaatctcct
     6181 gatctgtcag cacattcttt gcaccaccgg atccgcgggt ttcaatcttc acaaagcagt
     6241 tctttgcttt tgcagctttt tcaattcctt ctgctgccat gtacgtatgt gcgataccgg
     6301 taggacagga agtaacagca aggatcttcg cctgtgttcc ttctgctgat ccggtatctg
     6361 ccagtctctc atcaatatct ttcttttcac tgtctgccct gtcaataata tccataaact
     6421 catctactga agatgcattg cgaagagatt ctgtaaactc ctcatccatc agcatcacag
     6481 aaagcttgct gagtacatcc agatgaatgt tatcctctgt attcggcgct gcgatcagaa
     6541 acaataaagt tacaggttcg tcatccagag cttcaaactc tacaccattt ttgatgacca
     6601 ttgccgcaag tcccggcttc ttaactgcat cacatttacc atgaggaatg gcaattccct
     6661 cgccaatacc tgttgtgctc tcttcttctc ttaaatatac ctgtttacga taagcctcac
     6721 ggtcgctgat cttctcactc tttaccatca gatcaactgc catatccaga gtttctgact
     6781 ttgttttcgg agcagctgtt aacgatacgc ttcgtctgtc aagcaggtct gttattctca
     6841 tctcttcttc cccctttatt atttttcggt tatctgacga taaaccgctt ctatttcttc
     6901 ctttgttgca agattttcag aaaatgcact tgcacttcct gctgcaattc ccatgtggaa
     6961 tgcatgttcg taatccttct tctccatcca gcctgcaacg aatcctgcta ccatggaatc
     7021 tcctgcaccc acaccattta ccagcctgcc ttttggtgca ggttcttcaa atacctgtcc
     7081 atcctctgct accagaactg caccttcgcc ggccatggag atcagcacat ttcttgcacc
     7141 tttttcctga agtttctttc cataaggaat tacatctttt cttgttttta attctacacc
     7201 gaagatttcg cccagttcat gattatttgg ttttacaagg aacggatgat atttcaggac
     7261 attgaccaga agatcctttg tggcatcaac tacgatcatc acaccttttc catccagcct
     7321 tgccatgatc tgttcataca tgtcatccgg catagaagat ggaatgctgc ctgccaggaa
     7381 aagtacatcg ccttctccaa gctcttccag tttcttcatc agttcctcta ctttatcctt
     7441 gctgatcacc ggtcctgcac cattgatctc ggttccgtca atagatttca gtttcagatt
     7501 gatccttgaa accccttcac taatctgaat gaactcagat ttcactccca tctcatgtaa
     7561 tctacggata atttctttcc ctacaaaccc tgcagtaaat ccaagtgcag tgttctcaat
     7621 cccaagattc ataaggactg tggaaacatt aattcccttt ccccccggaa gcatcagctc
     7681 tgaacttgtt ctgtttgtca gccccagttt aaaatcatct accgaaacga tatagtccag
     7741 agatggatta aaagtcactg tgtaaatcat ctcttcttgc cctcccgttt tatattggta
     7801 tcctttcgga gtctttattt cactttcacc aaaagattcc aaaagtacat attgtcatgt
     7861 cttttctgca tgttcatgac tgttttttgt ttatgatctt agtatactgt catattcatc
     7921 caaagtcaat caaactaatt cataaaaata atgactgatt ttggtttact ttgcacaaaa
     7981 agtcataatc agtcaaatgc aagcagaaaa aatcctctga tcaggattgc tataaattcc
     8041 ataatcagag gatttactgt tattttatta cttttgattc cttacatttt atgcttttct
     8101 gctgcaaaga acgcttttgt ttcttttacg atcactccac ttaatgcgaa caatgcgatc
     8161 atattcggaa tcgccatcag tccgttgaag atatctgcga ttgtccatac agcacttact
     8221 gtcatgtacg gtccgataaa tactgccaga atgtaaagcc agcgatatgt aaggattgtt
     8281 ttcttatgtc cgtttgtcag atattccaga catctttcac tgtaataatc ccatccaaga
     8341 attgtagtaa atgcaaagaa taccagacag atcattaata caaatgcaga aatctgtcca
     8401 gggatcggaa gtccatgctg gaatgcatag gttgttacct gaacaccttc cagaccttct
     8461 acctgccatg cacctgtcag aacgatggaa agacctgtca ttgtacagat cacgatcgta
     8521 tcaataaatg taccagtcat gcttacaaga ccctgacgta caggctcttt tgtctgagct
     8581 gctgctgctg cgataggtgc gctaccaaga cctgcttcat ttgaaaagat accacgagcc
     8641 acacctttct gcatggatac gatcattgtt cctaccacac cacctgtcac tgctgacgga
     8701 ttaaaggctc ccttcacaac tgttacgata gctgccggga tctctgtaat gtttaaaaga
     8761 atcagcgcaa cactgaagat cagatagatc accgccataa acggtacaat aatctggctg
     8821 actgttgcaa ttcgtttcag accaccgatg aggattgctg caacacaggc tgcaagaatc
     8881 agggaagaaa ttacaactgc ccaggaatac tctccaagga acggaatatt tacgcagttt
     8941 gatttgttcg gatcaaagaa gttctgaact gcactggaaa taccatttac ctggctgaat
     9001 gtaccgattc cgaaaagacc tacacataca ccaaagaatg caaaaatctt tgcaagccat
     9061 ttccattttg ttcccatacc tttctcaata taatagaaag gaccgccaag gctgtgacca
     9121 tcttctgcta ccacacggta tttcactgca agaagacctt cggaaaattt tgttgccatt
     9181 ccgaagaatg ctgcaagaat catccagaat aaagctccgg gacctccggc acagacagca
     9241 gttgcaacgc cgacgatatt accggttccg attgtggcgc tcagtgctgt acataaagct
     9301 gcaaagctgg aaatctcacc atcgccttct tcttcgttct taaacatcca tttcaatgca
     9361 agagggagtc ttcgcatctg aagaagtcca agtctggcag ttaacaggat accacctgcc
     9421 ataatcagga ccataagggg cacgccccag accagattgt ctactgttgt caaaaaagaa
     9481 ttgatcgctt cccacataat aataaatctc ctttttcttt taaaaagtgt aatatattgt
     9541 acagctggga aacaaagtaa taacagaccg tttcaaaaat cagaagttca gaaaatactg
     9601 ttcatatagt tcatatgaat cagcggggat gataaagcat cctctgtcct tttgcctgag
     9661 agattcaaga cacgaatcag ataaccattt gtgggcagct attgataatt cgtgttattt
     9721 gcaccttcgg cccccgatct aacgggtgtc tccagagaaa cgatccattt gcagttcttc
     9781 cctgcatcca gggaacctga gagttttact ccttcggcgg gtatagcctt ttatgtggct
     9841 tcctctttcc tgcaaacttc acctcgttaa tttgctgtta ctgtggtata ctatagctct
     9901 taaatttgaa ctcgtcaata gaaaattaaa cttttataaa aaaagtataa aaattccaga
     9961 gatttccacc ttgtaaaatc cctggatatt taaataattt ttatacatca gccatatcag
    10021 ctgcaaacag cgccgcgcca agtgcaccgc aaagctgagc cttgtcactg attaccagct
    10081 ttgttccaag cttctcttcc agtgtcttta ccaggccctt attcttagaa acaccaccgg
    10141 tcatcatata tttctcctca ccgcccacac gtctggtaag agctgcggtt tttacggcaa
    10201 ccgccttatt cagaccatga acaatatcat ctgttgcctt attctgggcg atcagggata
    10261 caacttctga ttctgcaaat actgtacaca tactggaaat tgtaatatct tctttgaatt
    10321 ccagcccaca ttcgctcatc tgatccagat tcatttccat ggtacgtgcc atcatttcca
    10381 gaaatcgtcc ggttcctgcc gcacatttgt cattcataac aaagtttgca actgcacctt
    10441 tctcatccag tcggatcacc ttgctgtcct gtccgccaat atcaataaca gtacggactt
    10501 ccggattcag gaaatgcgca cctcttgcat gacaggtgat ctctgtgata ctcttatcac
    10561 catttttaat agctgtacgt ccgtatccgg tagtaaccag cgcatcaata tcttctctct
    10621 gcaatccggc ctccttcaat gcctctgcaa gggcacggtc tgctccgata gcagctcctg
    10681 ctcctgtagg caggataatg ctggtcacaa tctcatgatc tttatttaaa atcaccacat
    10741 ctgtactggt ggaaccactg tcaatccctg cgaaataacc ttttcccatt tttctctctc
    10801 cttttgtgtc tccatctatg gtctgctcca gtgtttcagg ctgaatgctc tctgcaaaag
    10861 cttccagtct ggtaagaagc tgaccgctgc tctgaatagt ataatctgat tcgattttta
    10921 aaagaggtac atctgtatga ttcttgatct cagcatattc gaagctgtaa aaatcacaaa
    10981 atttcactgt atgataaata atccccgcaa cagacggatc attataaagc ttcttacgac
    11041 ctgtcgggtc catcatacgc atacatggaa tctgccccag aatctcacct gcataccagt
    11101 ccatcaactc atcaaaagaa gcaccctccg gtggaagtat atttcccaca gaacggttat
    11161 gcacgcaggt atcattctct acaggaagag gcatagcttt actggtcatt tcaaataatt
    11221 cctgccccat tctggcgcca agcactgcaa tatgggactt tgtgattttc tcctgtgcat
    11281 ggaaagcagc ccggaatttt ccggcatcaa actctgtgcc tttgtactgt gcataagcct
    11341 tcgccagccc ttttaactgt acagccatac gctctctgct acaggcactg tcacagtgaa
    11401 gcacatccaa aatatagaga aaatccagct tgccgctttc aagcagaatg tcatagacac
    11461 tccggatagt atcacagcag ctcaccagga caagttcctt gattttcccc tccatgactc
    11521 cttccagaag tgtttttcca aaaccgcaga tattgggatg tgaaacctga tcggccaggt
    11581 caaatccctc cggcatatga ttaaagttct cacattcccc gccaagagat tccagaagtt
    11641 caattggggt atatttacag acatagtaag ttttattcat tctcagcacc tcccagcatt
    11701 tccagaaaag ctcccagcct ggtggaagtc tgtccttctc ctccatggct tcgatcacac
    11761 ccgtcaccgt ccaggatcaa aaggggcaga ccggcttcct cgaacttctt ctttgcaagc
    11821 tgtgccgcac caagcgtatg tttacatccc caatgtccaa accacacagc accgtctgct
    11881 cctgcctgtt tcgcatggcg gataccggct tcaatccttc taagggcact tccgttcagt
    11941 gaatgatata ccattctttc tgccattgct tcaaaggggt tctcaggatc aaaatccggc
    12001 tcacaggttt ctgcaagttc acatcctacg atctgggctt tctcactgaa gcaaagctcc
    12061 tggcgcactg catccgacca gaatggaatg gtatgcatcc agtaaatgtg cttccctttc
    12121 gctgccggtg ctttcttaat atcttcaaga agcatctgtg tatacttctc ttcttctgct
    12181 gttcccagaa ggatattgtt tgtcattcct gcatacaagg gtgtgaccag atcagagggc
    12241 acatatctgt ctgcacgcat ctgctgatat tttttgtaat tctccagagt ccgcttactg
    12301 caggcaagac gttcctttaa tctgtcctca gagattgttt ttcctgtatt tttttccaga
    12361 aatattttta aatcctttaa ctgatctgcc acatactgta cattctctgt ggtctgattc
    12421 catggtacat caatggcaaa tacaggtacc tggtaaaaat ctgccagggt acggaaggtg
    12481 agcaggttag catcgcaggt caggttggta taaacaatac atttaggctt tggcagaagt
    12541 cctttctgcg ctgcaccaag aaatgtcttg tgataactgc acagtgtctc tgcaattccc
    12601 tgattctctg cctgctgcaa aaatgccctc tctgctttgc ttgcagaaag atagcaggaa
    12661 aatccttcta cattataggg atgtaatccc acctcctgca tcatttcgca gggtgtaaaa
    12721 atacttacaa taacagaatc ttccggtttc tgaaggggcc acagcatggt atccatcatc
    12781 aggtttgcaa gatgcctgtc tgcaggcatc agtctcttgt cctgcatgta acggaacttc
    12841 agattctgcg cctcccaacc ggtttttaac agccggcggg ctgactgagg ctttttatcc
    12901 gtcagatttt ccacataatg accaaatgtc tcaataatct ccatagtctg tctcttcctc
    12961 attatggtaa taataattta tcaattgtca gtgcacaaat agtgccacgg aatattttaa
    13021 taatatcttt tttggaagtc aagttgaatt ttcgttactg ttcacacacc actattctgc
    13081 gaggtgtttt ggcatgaata tgccaaaatc ccgagacata caagccaaaa ttccattgcc
    13141 gcaggcaatc tggaatgaat tttggctaag ttactgtgaa cggagtgaac caatggtatt
    13201 tagataaata aagcatattc cggagattac tt
//
