LOCUS       c00013_gnlPro..        13705 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CPEIDPCF_13.
ACCESSION   c00013_gnlPro..
VERSION     c00013_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 23:36:15
            Original ID  :: gnl|Prokka|CPEIDPCF_13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13705
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13705
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[215:3705]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      216..3705
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13705
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13705
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(216..983)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_1"
                     /sec_met_domain="Fer2_3 (E-value: 2.4e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 7.9e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.5e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1024..2982)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.4e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3004..3705)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_3"
                     /sec_met_domain="SucD_FumR (E-value: 2.7e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3906..4178
                     /locus_tag="ctg13_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4211..4996
                     /locus_tag="ctg13_5"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5030..5263)
                     /locus_tag="ctg13_6"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLCRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5695..6402)
                     /locus_tag="ctg13_7"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYNGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             6591..8246
                     /locus_tag="ctg13_8"
                     /transl_table=11
                     /translation="MRKDEEVLTKKLLFNGIFIFFRMRWSDDFSLPENGGHLEKSYGFQ
                     IRTHIKMFRCNRVNGCCIAWWSIFSFLICYYSSYVSPYYEIPVSCDPIIYHLMGRGMME
                     GLMPYRDLFDQKGPFIFLIYGFSYALCGSYWLVFVLEVFAVTASMIFCYKAALLFVSGK
                     KAFIVSLLILYSMCSFHYYAGGGHPSEFILPFQFAAIYGVCRLYRDPDRFVRTGVVFGA
                     GIGMALLLKFNLAAFWFVPFLYVLYRARMTGKAWIFTGSVGGTLLLMLTPCLWYFYSRG
                     ALLDLYEGYIVFNAGYGADAVSFKEMCRNYSQWVKRDIMYPSMLMYIVGGAGVILSRMP
                     AREKIYYTAAFLITCMGVQGNGKTHFNHYAQTLIPFAAVGYLVVARMIHVEEVVSRKWR
                     RWLFPLVVAGVMACTFLNCVDFSCRSRAREWMSAFALPDTSDEPEGENACAVLGRHAVW
                     FYCVNGLVPPIRTFTICASDKQGAERERMRQYQEIRRGKIDYVVIAGEYFKPDNTESPS
                     LRAMRDLLSTEYCRERSFFREVTNLDIYRRVKRD"
     CDS             complement(8243..9127)
                     /locus_tag="ctg13_9"
                     /transl_table=11
                     /translation="MTLFLAGPTGSGKSAVAVELAEMLDAEIVSSDAYQVYRELPILTA
                     APSPADRERVPHHMVSIIPVQKNWNATEHYHRAMRCMEEIHARGKIAIVTGGSGLYFKF
                     LSHGLSEAPPGDAALRAAFANCSTEALYARLSSLDPEGAASTDAANRRYVERNLEIVLA
                     GGKPLSFWKRNWLTPPRGPGWVISRDVPELDERIAHRAARMMQEGAVEETASLGPCSAT
                     AERTLGLALIRSMLRGEISRENCQGQLALATRQYAKRQRTWLKREQWLRKLPASPSDSP
                     RTLAERIMEELGH"
     CDS             complement(9211..9951)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_10"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 1.4e-10, bitscore:
                     33.9, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFPKKIKACILFLLLTVPAALGAVWCAKHAYRYHLAVHPLPYSPE
                     QGALLEKHRQDKRNARLNPHAPVLFLGSSTMEFWLKEGKHSWETWFSPLGCLNLGTRSE
                     TTGNLLWRLNDGLTSPLAPRIIVLYSGVNNLGVQKSLGWTAFQGNVAIVKKIREIYSPE
                     TTAIIVIPPLIAQKGSRMETFRNCLLQHDFGENVHVLPLHFFLPGKDASLYTWDGLHLN
                     ALGYEAISPPLFRFLQQLLSRSSF"
     CDS             complement(9932..11035)
                     /locus_tag="ctg13_11"
                     /transl_table=11
                     /translation="MTPQNPTILLPSSREHWIDISRFLAACLIVCVHAPAFSFASLFQL
                     PVFNGRVAFFLILAGYFMGRNNSWNKAFKRGYTLLIPFLFWNIVISFLHPGIMNMGLPE
                     YLCNLAGFRSLFTPDFIPLSINGLTGEPFSPPTWFLRDIILCSLISPILLKLKYPVFVL
                     ILICFSTDWLQYPVPANKVTLAPSTVSLFSLGLFLSSIKLAEVKHVYKNSFTPLVLLAV
                     GTGFLLSITNYLSVCQNNPEWNMHKILASYGVWNISWPAVHLNSLCPVFGALLLMALGI
                     WLEKKIPVARKLSNYAPACFLIFVLHYPLIMLIPSHIWKQSFFAPFVLIPAIIFLIVAF
                     YLFLRKFFPACLPYVANDRITHVPKKN"
     CDS             complement(11082..11699)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hexapep_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_12"
                     /sec_met_domain="Hexapep_2 (E-value: 7e-15, bitscore: 46.7,
                     seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLFLIHLLSGIGRLLLRLRGVRTGTGIILSGFPLIKKFPGASIT
                     IGNGVTIHSLTRMNPVLSHHTCLAALSNQASIILEDGCGISGATLVCVNGIRIGRHTLI
                     GADALILDNDMHYPRSGARWGSTLGQPEQGQPISIGEGCFIGARATILKGVTIGSGSVV
                     AAGAVVTRDVPPGCLAIGNPAVNKPLPERLKHPRETQKAICP"
     CDS             complement(11699..12844)
                     /locus_tag="ctg13_13"
                     /transl_table=11
                     /translation="MPTKRLRPVLAIAADLPLGRLLTSFRNKDRRTIPWIFSLFHALES
                     QEDFDIHWITLSKAVSAAETIRMRNQTIHILPLGSMGRNILTAHFLTVRRIRKTLNDIQ
                     PDLLHVWGVEQAYALAGITFRGKKLLSYQGALTAYCQRAPQAFLLHMQALWERMAVKHY
                     DFITCESPWACDRVAEIAPHARLSCMEYGVEPSFYHLVRKPSPEPSCLFAGTIYELKGI
                     SYLVEAFTHPSLSHVQLFIAGNGALRERLEALSTPNIHWLGSISRAELQQHLSTAWFLV
                     HPTLGDCCPNIVKEARVMGLPVITTEEGGQTQYVQDGVSGYIVPVRNSAAVREAAQKLS
                     VSLDKAMSMGMERHQECRRLLDVKQTVTGCLSRYHTMLYPR"
ORIGIN
        1 ggggcctgct taggtttcgt ccggcatttc caagtacggt ttcctggatt actgggtgcc
       61 ttccagtgta acatttattt tttacgctgc gcgacgatga ggaagcaact gtctgatatt
      121 ttattcctgg ttcaaggaaa cctgataatg aaaaaaactc ccgacagccg atgccgccgg
      181 gagtttttac agagcgtctt aagaaggaat cttctttaga aacagaggcc ttccttggcg
      241 ttggctcgca tgaagtcgcg gttgaggcgg gcgatgttgt ccacgctgat gcctttcggg
      301 caggcagctt cacattcata ctggttcgtg cagttgccga agccttccgc ttccatctgc
      361 ttcatcatgg ccaggacgcg cttggaacgt tccggctggc cctgcggcag cagattgaga
      421 tgggcgatct tggcggaggt gaacagcatg gcggaggcgt ttttacagga ggccacgcag
      481 gcgccgcagc cgatgcaggc ggccgcgtca aaggcggcgt ccgccttcac tttttccacg
      541 gcgatgttgt tggcgttcgg cgcggaaccg gtacgcacgt caatatagcc tccggcggcg
      601 atgatgcggt ccagggcgga gcggtccacc atcaggtccc gcaggattgg gaaagccttc
      661 gcgcggaagg gttcaatcca gacggtatcg ccgtccttga acttgcgcat gtgaagctgg
      721 caagtggtca cctggcgttc cggcccgtgg ggaatgccgt tgatggtcag ggagcacatg
      781 ccgcagatgc cttcccggca gtcgtggtca aaatggatgg gttccttgcc ttccttgacc
      841 aggccttcat tgacgatgtc cagcatttcc aggaaggagg cgtccaccgg aatgtccttg
      901 gcggcatagg tctcaatgcg gcccttggct tcccggtttt cctggcgcca gaccttgaga
      961 gtgagattga gtgttttagc catgttataa tctttctttt gagtgttaat gtattggcta
     1021 tctttacttg tagctgcgga tggcaaggtg cacgttctcg aaggtcagcg gttccttgtg
     1081 gagaacaggc aggctgtcca cgccagtgta ttcccaggcg gctacatagg cgtattcatc
     1141 gtcgttgcgc ttggcttcgc cgtccggcag ctggtattcc acgcggaagt gggcgccgca
     1201 ggattcctgg cggttcaggg cgtcatagca gagcagctgg gcgaattcca ggaagtcggc
     1261 cacgcggcag gctttttcca gttccgcgtt gatgccgtcc gccgtgccgg ttacgcgcac
     1321 gttttcccag aattccttgc ggagctgggg aatgcgttca atggcgtggg tcaggctttc
     1381 ttccgtgcgg gccatgccgc agtcttccca catgatgagg cccagttccc ggtggaagga
     1441 gtccaccgtc ttggtgccct tcacattcag gagcttgttg atgcgttcct tcacttcgtc
     1501 ttccgcagcc ttgaattccg gggcggcggt ggtgacggca ccgggcttgg tggtcgtcag
     1561 gtaagcgggc agcgtggcgg gaatgacgaa gtagccgtca gacaggccct gcatcagggc
     1621 ggaggctccc aggcggttgg cgccgtggtc ggagaagttg gcttcaccga ggacgtgcag
     1681 ccccttcacg ttggacatga ggttgtagtc cacccacagg ccgcccatgg tgtagtggga
     1741 ggcggggtag atcatcatgg gcgtttcatg ggggtcgtcg tccgtgattt cttcgtacat
     1801 gtcaaacaga ttgccgtatt ggccgtcaat ccattcgcgg cccatgcgct tgatttcatc
     1861 cgcaaaatcc aggaagacgc ccttgccggt gacggccacg ccgcggccgt cgtcgcaggc
     1921 ttccttggcg gcgcgggagg aaatgtcgcg cggagccagg ttgccgaagg agggatactt
     1981 gcgttccagg tagtagtccc gttcttcttc gggaacatcg gaaggcttga tttccttctt
     2041 acggattttt tctgcggttt cacgggactt gggcacccag atgcggccgc tgttgcggag
     2101 ggattccgac atcagcgtca gtttggactg gtagtcgcct ttgaccggaa tgcaggtggg
     2161 gtggatttgc gtgaagcagg ggttggcgaa gaaggcacca cgcttgtagg ctttgtaggc
     2221 ggcagtgacg ttgcaaccca tcgcgttggt ggacaggaag aacacgttgc cgtagccgcc
     2281 cgtgcagagc aggacggtat cccctgcgta ggatttgatt tcgccggtaa ccagattgcg
     2341 ggtgacgatg cccttggctt cgccgtccac cagcaccaga tccatcattt catggcgcga
     2401 gaacatttca atgtgtccct tggccacttc cttttccagg gcctggtagg cacccagcag
     2461 gagctgctgg cccgtctgtc cgcgtgcgta gaaggttcgc ttgagctggg cgccgccgaa
     2521 ggagcggttg tccagcaggc cgccgtattc acggccgaag ggaacgccct gggccacaca
     2581 ctggtcaatg atgttggagg agacttccgc cagacggtag acattggctt cacgggcgcg
     2641 gaagtcgccg cctttaacgg tgtcgtaaaa caggcggtaa acggagtcgc cgtcgttctg
     2701 gtagttcttg gctgcgttaa tgccgccctg ggccgcaatg gagtgggcgc ggcggggact
     2761 gtcctggtag cagaagcatt tgacgttgta gccaagttcg gcaagcgtgg cggcagcgga
     2821 ggcgccagcc aggccggaac ctaccacaag caccgtgtac ttgcgcttgt tgttcggatt
     2881 gatcagtttg gactcaagtt tgtacttgga ccatttgtcc tgaatagggc cggagggaat
     2941 tttggcatcc ggcatccagt cgcttacggg aaaattaatc atgactttga gaggagttga
     3001 tggttatttg atgataccca gaagaaccga gaccggcacg gagatgaagc ccaggcagat
     3061 aatcgcgccg taggcgatgg cgataaagtt gtagaagggc cggattttgc gggaatcgac
     3121 gcccacagtc tggaagatgg actgtacccc gtggcgcaga tggctgaaca gcatcagaac
     3181 ggccaggatg tagaaggcgg agcaccatac gttggagaat ccggtcacga tcatcttgta
     3241 cacgtcaaag gtttccaccg taccgtcgga aatgaaggtg gtgaactggg cggggtcgta
     3301 tcccacgcgc agggtgtact ggtacaggtg gtagatcagg aacaccagga cggtcaggcc
     3361 ggtatagatc atgtagcggg aggagagcgt cgccttgatg gtgttcttga acacgtaggg
     3421 ttcgcgggcc gcatggtttt ccagcttcag ctggatggtc agccagacgt ggatgatgaa
     3481 gatcaccgca agccccgcgc ggattcccca gagggctgct tccggcatgg agtgcaggcc
     3541 gtgggcgtag gtgttgatcc attcagggcc tccgaagatg agaaggttgc ctgccaggtg
     3601 tcccgcaagg aacaagacca aacataaccc cgtcagagcc acaatgattt tgcggccgat
     3661 ggaggatgtc acgaatgtac atatggtttt tactagtgca ttcataggcg ctctaatgaa
     3721 ataaatgcgt cttcacagga tgcccggttc aagcccggat ggcaagcctc ttcttgaatt
     3781 tccggcgctt ttcggatttt tgaaaagccg gggaaagagg ttgctgttta tcagtttgga
     3841 atggttatca ttttgttgcc tgttccggct tgacgaggct ttccgcatag gcgtatcgtc
     3901 tgtgcatgaa aagaagtaaa aaggaagtgc tggacgcgga tttcgcagcg gcgcgcgccg
     3961 gcgttctgga tgtggccgca tttctggacc gggtggaccg cggggaaggg gaggcggatt
     4021 tccgttacca tgccctgatg gatgttcttc ccctcttgtc cgcatccggc cccggacgtg
     4081 tccgggccat tctggaagcc ctttcctaca gggatgacac cgtgccggaa accgccgcag
     4141 ccaaagcggc ctgcggagcc ccgaacctca gcaaataaaa atgatggctt tcatagaacc
     4201 tcatatacat atggtgtgcc gcaccacgga cgaataccgg gccatggcgc aggccggctg
     4261 cctggcggta ggggaaccgg cgttctgggc cggttacgac cgttcgtccg cggacggttt
     4321 ccgggattat ttcgtacagc ttacggaatg cgaacccgcc agggcggcca agttcggcat
     4381 ggaccattac acatggctgt gcatcaatcc caaggaggcg caggacgtgg ctttcgcgcg
     4441 ggatgtgatg aaactgattc cggagttcat tgaccggccc aatgtcctcg gcatcgggga
     4501 aatagggctg aaccggaata cttcccatga aatgactatt tttgaagagc atctggatct
     4561 ggcggtgcgc ctcaaccagc ttgtgctgat tcacactccc catctggaag acaagcttaa
     4621 ggggaccgta atgattcttt ccgccctgaa aaaccgtccg gatctggacc cttgccgcgt
     4681 gttggtggat cactgtgagg aacatacctt cccgctggtg aaggaggccg gttactgggc
     4741 cgggctgacc ctttatccca ccagcaagct gaatcccaag cgggcggcgg atattctgga
     4801 attgtacgga atggaccgtg tctgggccaa ttccgcggcg gactgggggg attccgatcc
     4861 cctggcgctg acggccctgg cctgcgagct gcgcaggcgc ggtttttccc ggcaggaaac
     4921 ggaacgtctt ctcctggaaa atccggagac attcatggga cagtccccga agttccggaa
     4981 agtgtcgtcc cgctaattcc gcccgaggcg cggcggaggg tacggccctc tagtccccgt
     5041 ccgggaaaaa gacggtgagg acggcgccca ggatgaccgc cgcgtcatcc agaaggccca
     5101 gcctgccgat tccgtcaaac aggaattcgt cgggagtcag gatgtaggcg ccggcggcgg
     5161 ccagaaggca tatattccgt ttgttgaaaa aacgcggttc tccttttctg cttttgaaat
     5221 accggcacag gcgcagtagc agctgctgtt tttgaagatt catggacggg aacgggggat
     5281 aaaggttcaa gctcagccat tttcccactc cttttccctg tttcggggaa ggagtctgtt
     5341 gccgacggac ggaaaccgca gcgatccgga ccgtgcgggg aaatggattg ctgaaaggat
     5401 gggctgttcc ggatgctgag ggaagccggg ctttgcatgc tccggttccg gctgtcccgg
     5461 catgggaaaa aggggcgtgt acggaagtgg ggcggggtcg gaagctcttg aaatgaccct
     5521 cccgggggag cctgaatgcc atttccccgt caagtgctgg ccgtgagggt accgcagcaa
     5581 atggaagctt cttcccccct gttttttccg gcagatgttt gaacggataa ggaaaaggcc
     5641 ggctcacgat tttgtgagcc ggcctttgaa tatagggagg cggacggtac aggcttatgc
     5701 cctgcggcgg cgcatcatca gcgcggccag tcccagcagg cccagggaag ccgtggcggg
     5761 ttccgggatg ctggcgattt cactcatcag ttgaccaact tgttcctggg aaaggaggga
     5821 gtcgtggatg tagagctgtt cgatggattc agccagtcct gcgtccatga gaatctgatt
     5881 aatttgctgg ttgccgaatt tcaggccgct gttggaatag tacgtagcgc tgtcgccaaa
     5941 atagatgcgg gtgccaagat ctccggtgac tacggaaatg gtcagggaac cttccgtgcc
     6001 cagcggggtg tcaacgacgg gcccgttgta tgaggtgttg ttccataatc cctggagttt
     6061 ccggtccgtg ttcaggccca cgccccagct tacactgctg tttttggcgt taaacagagc
     6121 ggtataggcg tccggagtgt tgattttgga caggtcaaga accatcgtca cagacataac
     6181 gtcgcggttg ttggcaccgt atccgttgaa ggttatcccg gataacgtca gattgctgtc
     6241 gtcagacgtg atggaaacgg aatctttcag ggtgccgaaa tccgccgttt gggaggcaaa
     6301 gtccgaatat cccacgatgg agctatccag cagagaggta gccgcggtag cgcttaggct
     6361 catgccggcc gaaagaatca gggtggataa taatttattc atggtcagta tcttaataaa
     6421 atgatgcaag attcaatgta tgtacttgtg cttgaataac gaatttggaa tccgtagtca
     6481 atataataaa ttagaaaaaa gtattataat taatttacca cctctttaaa caggaagctg
     6541 gaatatggag aggtaaggcc cttcattttt tttcaggagg tatttccgtg atgaggaaag
     6601 atgaggaggt attaactaaa aaattgttgt tcaatggcat attcattttt ttcagaatgc
     6661 ggtggtctga tgatttcagt ctgccggaga acggaggcca cctggaaaaa agctacggat
     6721 tccaaatccg tacccatata aaaatgtttc gttgtaatag ggtaaatgga tgttgtattg
     6781 catggtggtc tattttctca tttctgattt gttattattc cagttatgtg tctccctatt
     6841 atgaaattcc cgtaagttgt gatcccatta tttatcatct catgggacgc ggaatgatgg
     6901 aagggttgat gccttatcgg gatttgtttg atcaaaaggg gcccttcatt tttttgatat
     6961 atggcttttc ctacgccttg tgtggttctt actggcttgt attcgttctt gaggtattcg
     7021 cagtgacggc ctccatgatc ttttgttaca aggcggccct tctcttcgta tctggaaaaa
     7081 aagcgtttat cgtttcgctg ctcatccttt attccatgtg cagtttccac tattatgcag
     7141 gaggaggtca tccctccgaa tttattctgc ctttccagtt tgccgcgatt tatggagtgt
     7201 gccgcctgta tcgggatccc gatcgcttcg taagaacggg cgtggtgttt ggcgcgggca
     7261 tcgggatggc gcttctgttg aaattcaact tggccgcttt ttggttcgtt cccttcctgt
     7321 atgtcctgta tcgtgcgcgg atgaccggga aggcatggat ttttacagga agcgtgggag
     7381 gaacgctcct gttgatgctg acgccctgcc tctggtattt ttacagccgc ggcgcgttgc
     7441 tggatttata tgaaggatac attgttttta atgccggtta cggcgccgat gcggtatcgt
     7501 tcaaggagat gtgccggaat tattcccaat gggtgaaaag ggatatcatg tatcctagca
     7561 tgttgatgta catcgtggga ggagcggggg tgattttaag ccggatgccc gctagggaaa
     7621 agatttatta tacagccgct tttctgatta cctgcatggg cgtccaggga aatggaaaga
     7681 cgcatttcaa ccattacgcc cagacactta ttcccttcgc tgctgtggga tacctggtgg
     7741 tggccaggat gatccatgtg gaagaggttg tttcccgaaa gtggcgccga tggctttttc
     7801 ctctggttgt tgcgggagtg atggcttgca ccttcctgaa ttgcgtggat ttttcatgca
     7861 gaagccgcgc ccgcgaatgg atgtccgctt ttgctcttcc agataccagt gatgaaccgg
     7921 agggggagaa tgcttgtgca gtccttgggc ggcatgccgt atggttttac tgtgtcaatg
     7981 gtttggtgcc gcccatacgc acgtttacga tttgcgcttc cgacaaacag ggtgcagaac
     8041 gggaaaggat gcgtcagtat caggaaatcc gccgcggaaa gatagactat gtggtgatag
     8101 cgggagaata cttcaagccg gacaacacgg aatctccctc cctgagggct atgcgggatt
     8161 tgctaagtac ggaatattgc cgggaacgat cctttttcag agaagtgacg aacttggata
     8221 tttaccgccg tgtgaagagg gattaatgcc ccagttcttc catgatgcgt tctgcaagag
     8281 tccggggaga gtcggaaggg gaagccggaa gtttccgaag ccattgttcg cgtttcagcc
     8341 aggtgcgctg ccgtttggcg tattgccggg tggcgagggc cagctggccc tggcagtttt
     8401 cacgggagat ttccccgcgc agcatgcttc gtatcaacgc caggcccaga gtgcgttccg
     8461 ctgtggcgga gcatgggccg agggaagccg tttcctccac ggccccctcc tgcatcatgc
     8521 gtgcggcacg gtgggctatt ctttcgtcca gttcaggaac atccctgctg atgacccagc
     8581 cgggcccgcg cggcggggtc agccagttcc tcttccagaa ggaaagaggt ttccctccgg
     8641 caaggacgat ttccagattg cgttccacat aacgccggtt ggcggcatcc gtcgaggccg
     8701 ctccttccgg gtccagggaa gagagcctgg cgtatagcgc ttccgtggaa cagttcgcga
     8761 aagcggcgcg gagagcagcg tcccccggcg gcgcttccga caggccgtgg gagaggaatt
     8821 tgaagtacag gccggaaccg cccgtgacga tggcgatttt tccgcgtgcg tgaatttctt
     8881 ccatgcagcg catggcgcgg tggtagtgtt ccgtggcatt ccagttcttt tggaccggaa
     8941 tgatggaaac catgtggtgg gggacccgtt cccggtctgc cggggaaggc gccgccgtca
     9001 ggatgggcag ctcccggtac acctggtaag cgtcggaact gacgatttct gcgtccagca
     9061 tctccgccag ttccacggct accgcggatt tgcccgatcc ggtgggacct gccaggaaca
     9121 gggtcatggg aagtgttgcc tgatggggtg gaaaaggttc aatcatcacg tggagtaatg
     9181 gcggataaag tttgttgttt ctgtgaagcc ctaaaagctg ctcctgctta aaagctgttg
     9241 gaggaagcgg aaaagcggag gcgaaatggc ttcatatccc agggcgttga gatgaaggcc
     9301 gtcccaagta taaaggctgg catcctttcc cggaaggaag aaatggaggg ggaggacatg
     9361 gacattttct ccaaagtcgt gttgcagcag acaattcctg aaggtttcca tacgcgaccc
     9421 tttttgtgcg atgagcgggg gaatgacaat gatggcggtc gtttccgggc tgtaaatctc
     9481 cctgattttt ttgacgatgg ccacgtttcc ctgaaaagcc gtccatccca ggcttttttg
     9541 tactcccaga ttgttgactc ccgaatacag gacgatgatt ctgggcgcca gcgggcttgt
     9601 caggccgtca ttgaggcgcc agagcaggtt gcccgtggtc tcgctcctgg ttcccaggtt
     9661 gaggcatccc agaggggaaa accaggtttc ccaggaatgt ttcccttctt tcagccagaa
     9721 ttccatggtg gaggaaccca ggaacaacac gggggcatgg ggattcagcc gggcattgcg
     9781 tttgtcctgc cggtgttttt ccagcagggc gccctgttcc ggggaatagg gaaggggatg
     9841 gacagccaaa tggtagcggt aggcgtgttt ggcgcaccag acggcgccta atgcggccgg
     9901 aacggttaaa agaagaaaga ggatacaggc cttaattttt tttgggaaca tgggtgatgc
     9961 ggtcgttggc gacgtagggc aggcaggccg ggaagaattt tctcaggaaa agatagaatg
    10021 cgacgataag gaaaatgatg gccggtatta atacaaaggg agcgaaaaag gattgtttcc
    10081 agatgtggga ggggatcagc atgatcaaag gataatgaag aacgaatatc aggaaacagg
    10141 cgggagcata gttggacagc tttctggcaa cgggaatttt cttttccagc cagattccaa
    10201 gggccatgag aagaagcgcc ccgaagactg ggcagaggga attcaaatgg acagccggcc
    10261 aggagatatt ccatactcca taggatgcca gtattttgtg catgttccat tccgggttat
    10321 tctggcaaac gctcaagtaa ttggtgatgc tgagcagaaa cccggttcct acggcgagca
    10381 ggacgagggg agtaaaggaa tttttgtaaa cgtgttttac ttcagccagt ttgatggaag
    10441 acaggaaaag gcccagactg aacagggaga cggtggatgg agcaagggta accttgttgg
    10501 ccggcacggg gtattggagc cagtccgtgc tgaagcagat caggattagg acaaaaaccg
    10561 gatatttcaa tttcagcagg atgggggaaa tgagggaaca gagaatgata tccctcaaaa
    10621 accatgtggg aggggaaaag ggttctcccg tcaatccatt gatagaaaga ggaataaaat
    10681 cgggagtgaa aagggaacgg aagcctgcaa ggttgcataa gtattccggc agtcccatat
    10741 tcatgattcc cggatggagg aaagagatga ctatattcca gaacagaaag ggaatgagaa
    10801 gcgtataacc ccgtttgaac gctttgttcc aggaattatt ccggcccatg aaatagcctg
    10861 ccagaatcag gaaaaatgcc acgcggccgt tgaaaaccgg aagctggaac aggctggcga
    10921 aagagaaggc cggcgcgtgg acgcatacaa tcaggcatgc cgcgaggaat cgggatatgt
    10981 caatccaatg ttcccgggat gagggtaata aaattgtagg attttgcggt gtcatgaaag
    11041 agtctgcctt tggagccccc tgaggcaggc aggggaaatg ctcaagggca gatggctttt
    11101 tgtgtttccc ggggatgttt gagacgttcg gggagcggtt tatttactgc gggatttccg
    11161 atggccaggc agccgggagg cacatcccgg gtgacgacgg ctcctgcggc gactacggaa
    11221 ccggagccga tggtgactcc tttcaaaatg gtggccctgg cgccgatgaa gcatccttcc
    11281 ccgatggaaa tgggttgtcc ctgttcgggc tgtcccaggg ttgatcccca cctggcgccg
    11341 ctccggggat agtgcatgtc gttgtccaga atcagcgcgt ctgctcctat cagcgtgtgg
    11401 cggccgatgc ggatgccgtt gacgcagacc agggtggctc cgctgatgcc gcagccgtcc
    11461 tccagaatga tgcttgcctg attggaaagg gcggccaggc aggtgtgatg ggaaagtacc
    11521 ggattcatcc gggtcaggga gtggatggtg actccgttgc cgatggtgat ggacgctccc
    11581 gggaattttt taatgagggg aaatccggaa agaatgatgc ctgttccggt gcgcaccccc
    11641 ctgagcctga gcagcaggcg gcctatcccg gaaagcagat ggataaggaa taatttcatc
    11701 agcgtggata cagcatggta tgataacgtg acaggcaccc ggttactgtc tgctttacgt
    11761 ccagcaggcg gcggcattcc tgatgccgct ccattcccat ggacatggcc ttatccaggc
    11821 tgacggaaag tttctgcgcg gcttccctga cggcggcgct gttgcggacc gggacaatat
    11881 agccggatac gccgtcctgg acatattgag tctgtccgcc ttcttccgtg gtgattaccg
    11941 gaaggcccat gactcttgcc tccttcacga tgttggggca gcaatccccc agggtgggat
    12001 gcaccaggaa ccacgccgtg gaaaggtgct gctgaagttc tgcgcgggaa atgctgccca
    12061 gccagtggat attgggagtg gacagggctt ccagcctttc cctgagggct ccgttgcccg
    12121 caatgaacag ctggacatgg gaaagggacg gatgcgtgaa agcctccacc aggtaggaaa
    12181 tgcccttcaa ctcgtaaatg gttccggcaa agaggcagga aggttccggg gaaggttttc
    12241 tgacaagatg gtaaaaggaa ggttccacgc cgtattccat gcaggacagg cgggcatggg
    12301 gggcaatttc cgcaacgcgg tcgcacgccc agggggattc gcacgtgata aaatcataat
    12361 gtttgacggc catccgttcc cagagggcct gcatatggag gaggaaggcc tgcggagcgc
    12421 gctggcagta ggcggtgagg gctccttggt aggaaaggag cttctttccc cggaaggtaa
    12481 tccccgccag agcgtaagcc tgctccactc cccatacgtg caggagatcc ggctggatat
    12541 cgttcagagt cttgcgtatt ctccggacgg tcaggaaatg ggccgtcagg atattcctgc
    12601 ccatgctgcc caggggaagg atgtggatgg tctggttgcg catccggatg gtttccgcgg
    12661 cggaaacggc tttgctgaga gtaatccagt ggatgtcaaa atcttcctga gattccagag
    12721 catgaaaaag ggaaaaaatc cagggaatcg tacgccggtc tttgttacgg aaagacgtca
    12781 gcagccggcc cagagggagg tccgctgcta tggctaatac gggacggagg cgtttggtcg
    12841 gcatggattg gaaaaaagga ggcaaggtta gcaggtgggt aaatgctccc ggacgatgga
    12901 agacgcgaac ggaggctttc cttccgggcg gatggaggaa aaaagcagtt gctcccattc
    12961 ctggtttact gcgtcggggg cgaaacgggc ttcccattgc cggcggcctt tactccccag
    13021 tagtttgcgt gttttttcgt ccgtcaacga ttccacagct ttttccagcg cggaggggga
    13081 tgcgtttttc aggacgattc ccccttccag ggtggaaaga gctcctgcgt ccggagcgaa
    13141 ccagggaacg ccgcatgaca tcgcctccag aatggagagg ggctgctgtt cctgataaga
    13201 gtaaaggaaa acggcatcgc tttccataat ggcggcttct acctccaaac gggggagcct
    13261 gtagagaatc ctgaatctgg ggtcatcacc gatggcctgt tccatttgtt ccgcgtaggc
    13321 attgcgctgg ggaatgagaa aaagaaaaat gatatgccgc agacgggagc gtttcacatg
    13381 gcggatgaag agaagctgcc gtttcctcat gctggcgccg gcagggcagg tgaaaacggg
    13441 ggcggaggaa agtccgtatt tttcccggaa aaaaggagcg gttcttttca gagccgggaa
    13501 tgtgttggga atgcaggagt aatgggcaag tttgcttctg gatgcgcagt aataatcaaa
    13561 gctcttgaac agtgtcccgt aagggtcgag aaaaacgaga cggtttaacg gtgatttcct
    13621 gcatacgttg aggatattcc tgcgtatttg aaaaaaggag cggagccatt ttttcaggcc
    13681 gaagaaagga gggtaattga agcgg
//
