LOCUS       c00015_gnlPro..        11904 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HEKCBFPP_15.
ACCESSION   c00015_gnlPro..
VERSION     c00015_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:46:57
            Original ID  :: gnl|Prokka|HEKCBFPP_15
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11904
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11904
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1295:11903]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1296..11903
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..11904
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /kind="single"
                     /product="OD_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11904
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="OD_AA_metabolism"
                     /region_number="1"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG,
                     Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /tool="gutsmash"
     CDS             217..645
                     /locus_tag="ctg15_1"
                     /transl_table=11
                     /translation="MIVIVSILLVISIIDFKIKIIPNQLNVLLFISGIWSGFVFQEVTF
                     LSRFLGVFSVSIPMFMLAILCSGGLGGGDVKLMAASGVLLGIKWNIFAACAGLLLGGLY
                     GFFLLITKRAKRKDCFALGPFLCIGIAVVFFRYIFMKV"
     CDS             1296..4853
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EKR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_2"
                     /sec_met_domain="PFOR_II (E-value: 1.5e-17, bitscore: 52.6,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.4e-78, bitscore: 250.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 8.8e-36, bitscore: 112.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.3e-13, bitscore:
                     37.8, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_7 (E-value: 2.6e-11, bitscore: 32.8,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00012, bitscore: 11.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 9.5e-20, bitscore: 59.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRAKQSMDGNTAAAHVAYAYTDVAAIYPITPSSPMADSVDQWAA
                     AGQENIFGNQVVVSEMQSEAGAAGTVHGSLAAGAITTTFTASQGLLLMIPNMYKIAAEQ
                     LPCVFDVSARTVATQSLNIFGDHSDVYACRQTGFAMLAETNPQEVMDLSPVAHLAAIEG
                     KVPFINFFDGFRTSHEIQKIEKWDYADLKEMCNMDAVKAFREHALNPEHPAMRGSHENG
                     DVFFQHREACNSVYEALPAVVKKYMGKINEKLGTNYDLFNYYGAEDADRVIIAMGSICD
                     VAEEVIDYLTAKGEKVGLIKVRLYRPWVSSALLDVIPKTAKKIAVLDRTKEPGALGDPL
                     YLDVATTLREAGLNDIVLTAGRYGLGSKDTPPSSVFAIYKELEKDAPKSRFTIGIVDDV
                     TNLSLPEVKPAPITSAPGTVECKFWGLGGDGTVGANKNSTKIIGDHTDKYIQAYFQYDS
                     KKTGGITISHLRFGDNPIRSPYYINQADFVACHNPSYVVKGYKMVQDVKPGGIFMINCQ
                     WSDEELDHHMPAAAKKYIADNNIQLYTINAIDKAIEIGMGKRTNTILQSAFFKLANIMP
                     IDDAVEFMKAAAKKSYSKKGDAVVEMNYKAIDAGVDAVHKVEIPASWSNPAADAPAKEL
                     TGRPETVKMVKEMMEPIGIMDGDSLPVSTFVDNADGQFELGASAYEKRGTAVSVPEWNP
                     EACIQCNQCAFVCSHATIRPFLVSEDEIKAAPDNMKVADTKPKASEYKFTMSVSPLDCM
                     GCGECITVCPAAAKGALKMVPQESQAAEQPVFDYLVATVGRKPGAPADTTVKGSQFNQP
                     LLEFSGSCAGCAETSYARLITQLFGEHMYISNATGCSSIWGGPAATAPYTVNKDSKQGP
                     AWANSLFEDNAEHGFGMYLGQKTLRDQAIAKLEKMAASDKASDEFKAAFAKFMETKDNT
                     KENTPDAQALIAEVEKAAAAGCPDAAEVLEKKQYLAKKSVWIFGGDGWAYDIGFGGLDH
                     VLASGENVNVMVFDTEMYSNTGGQASKASNIGEVCQFAAAGKEISKKSLAEIAMSYGYV
                     YVAQIALGANPNQAVKCLAEAEAYNGPSLIIGYAPCELHGIAKGGMNHCQDEMKKAVKA
                     GYWNLFSFDPAKKAEGKNPFTLTSKEGDGSYQEFLNNESRYTRLIKPFPERAERLFNES
                     EKVAKARYEHLQRLVELYK"
     CDS             5051..5380
                     /locus_tag="ctg15_3"
                     /transl_table=11
                     /translation="MLYKEDFGEGKNIEFKREIPKRHEKLLKDVIAFSNSTGGKIFIGI
                     EDKTNEVIGIGEKNPFRLADDISNMIFDSCTPIIDPEITIQTLEGRTVVVVEVFPGRMR
                     PYYLK"
     CDS             5507..6805
                     /locus_tag="ctg15_4"
                     /transl_table=11
                     /translation="MEYSEREAKILCNAMEKVAYDVQTTCVTRAIQETSLDPKQNTEKT
                     EIINKMTIEKLEDLGLLCRIGKDLQPTHAFRLMTKNKIRYAKIQCALFKGTERDIFIDK
                     REFDGPLYVQLENAYQFVLKHINLGAKIEGLHRKEAYELPVRTIRELITNAVVHRSYLD
                     ESCIQVCVYDDRIEVTSPGMLYGGLDIQSAKSGKSKCRNTAIAEAFRYMGLIEAWGTGI
                     PRMIKECREYGLREPVFEELGDGIRVTIFRENEELEMRKRAENIQNAENKYQYMNNINS
                     ENLASVVKEQTVEYREQNHCFNTEKSLFNALDSQGNEKKYCLNDEKTLFETTSQDKTHC
                     FETSVLTAENKYMLYKKLEELQVNKSIGSVTALNIKEIIESFSGEEVFGRKEIKQKLGY
                     KDSKAGFLIQTMREFELIKAVKGRGKGKYCFDI"
     CDS             complement(6909..7577)
                     /locus_tag="ctg15_5"
                     /transl_table=11
                     /translation="MIINKFYEKLYKELINKLESDYILIPNTPENRKAINNTLTTVPCT
                     VKSLEKDSKIFKALSNKKAKAKQLSIVPKISKTLSLIIIATLICMPFNTINTLPTPTYH
                     PTVQVSILDISDGSSHQKGKNKLSEIQEQYTNKNQEQRNPKNYKKKVATNTYNTYKKQN
                     KFHLTLSTKKATQLLSTFKKFFLKTKNTYDNLSDAYDVISTLFVLISTVKKSIRSKKLK
                     "
     CDS             8646..11903
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: Glu_synthase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: Glu_syn_central"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_6"
                     /sec_met_domain="GATase_2 (E-value: 2.6e-173, bitscore:
                     565.1, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Glu_syn_central (E-value: 6.9e-113,
                     bitscore: 365.4, seeds: 570, tool: rule-based-clusters)"
                     /sec_met_domain="Glu_synthase (E-value: 2.6e-111, bitscore:
                     360.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYQDNMRQGLYDPSLEHDNCGIGAVVNIKGLKSHETVSNALKIVE
                     NLEHRAGKDAEGKTGDGVGILVQISHKFFEKTCSTLGFSIGKERDYGIGMFFMPQDELQ
                     RNRAKKMFEIIVEKEGLNFLGWREVPVQPGILGKKAADCMPCIMQGFVKRPFDVPRGLD
                     FDRRLYIVRRVFEQSNDSAYVVSLSSRTIVYKGMFLVGQLRLFYNDLQDKDYESAIALV
                     HSRFSTNTVPSWEKAHPYRYIVHNGEINTIRGNADKMLAREENMESDYLKDEMIKLTPV
                     VDPNGSDSARLDNTLEFLLMSGMPLPLAMMITIPEPWENNEGMSREKRDFYQYYATMME
                     PWDGPASILFTDGDIMGAVLDRNGLRPSRYYITDDDQLILSSEVGVLDFDTTHIVKKER
                     LHPGKMLLVDTVKGELIDDEILKDSYVKNQPYGEWLSDNLVFLKDLKIPNVAVEEYSYE
                     ESNRLMKAFGYSYEEVKDSVLPMALNGSEAIGAMGVDTPLAVLSKRHHPLFDYFKQLFA
                     QVTNPPIDAIREEIVTSTSIYVGGEGNVLEEKAENCHVLKIHNPILTNTDLLKIRYAKV
                     KNINVKDVPITYYKGTPLDKAINHLYVAVDQAHKNGANVVILTDRGVDENHVAIPSLLA
                     VSAVHHHLIETKKSTSVSIILESGEPREVHHFATLLGYGACAINPYLAQFSIKKLIQDG
                     LLKKDYYAAVNDYNNAVLHGIVKIASKMGISTLQSYQGSQIFEAVGISKKVIDEYFTNT
                     VSRVEGITIEDIAEDVDYHHSKAFDMLGLKNDLSLDSEGDHKYRSGKEEHLYNPLTIHT
                     LQTAAWTNNYELFKQYTSMINKETSPVSLRGLMDFNYPSKGVPIEEVESVDSIVKRFKT
                     GAMSYGSISKEAHETLAIAMNMIHGKSNTGEGGEDLERLTVGPDGLNKCSAIKQVASGR
                     FGVTSRYLVSAQEIQIKMAQGAKPGEGGHLPAGKVYPWIAKTRHSTPGVGLISPPPHHD
                     IYSIEDLAQLIYDLKNANRDARISVKLVSEAGVGTVAAGVAKAGAQVILISGHDGGTGA
                     APRNSSIHNAGLPWELGLAETHQTLIKNDLRNKVIIET"
ORIGIN
        1 cccacaaatt gtaacgcaca tcttgcagaa agcatttttc aaacacgctc tagatctgtc
       61 agtaggaatg gtttatagat taaacacatg ttaataactc cactgcaagg attttcataa
      121 ttatagtatt tggggttaca gggtctgtaa aatagtaaac ttaataaaaa ttctgcaatt
      181 agcaggagcc agggggagta tatgagggta attacaatga ttgttatagt tagtatttta
      241 ctggttattt ctataattga ttttaaaatc aagataattc cgaatcagtt aaatgtactt
      301 ttgtttattt caggaatctg gagtggtttt gttttccagg aagttacatt cttaagtcgc
      361 tttttgggag tgttttcggt tagtattccg atgttcatgc ttgcaatttt atgttcaggc
      421 ggactgggtg gaggagatgt taagctaatg gcggcaagtg gagtgttact agggataaag
      481 tggaatatat ttgctgcttg tgcgggatta cttttaggag gattatatgg attttttcta
      541 ctgattacaa agcgtgcgaa gcgaaaggat tgctttgcgc tgggaccttt tttgtgtata
      601 gggattgctg ttgtgttttt tagatatatt tttatgaaag tgtgagggag ataatatgga
      661 attaccgtgg attcccactt aattttcttt tcatcacttc tgagtaaaaa gtcgtttttc
      721 gtgaattgtc tcattgacat tttgtcaaat aacgtgcctg ttttcctata gagttgtgtt
      781 ggcttcattc agttgacgta gccgcccgtt acgctgcctt cattcaggca aaatctcctg
      841 caaattgtga cacacatctt gcagaaagca tttttcaaac acgtgctagt cgattaaatt
      901 atgtaaaatt acgaaattgt tatttttaaa agatggagat aaatggtgaa aacaaagagg
      961 aatctcataa aataattaaa aaaatgaaga aaaaatatta gaattttaat cctgaataat
     1021 cctaaaatta caacaaaaaa ttattgagaa aaaatctaaa ataagccata tgtatattgt
     1081 atacaaaact gttggtttta tagcaatttt aacctaaaat tgttctcgga aaaatacgtt
     1141 gtcaagggga aaaattggca taaaaaggct gtttcgggca agattttgta ttttagaagg
     1201 aacagttccg aataagcttt acattacctc aaaaaaatga taatattatg tcgaatttaa
     1261 aataaaccac aacttttgac aaggaggaat aatcaatgcc tagagcaaaa cagtctatgg
     1321 atggaaatac cgcagcagct cacgtagcat atgcgtatac agatgttgca gctatctatc
     1381 ctattacacc atctagtcca atggctgatt ccgttgacca gtgggcagca gcaggacagg
     1441 aaaatatttt tggtaaccag gtagttgtta gtgagatgca gtctgaggca ggtgcagcag
     1501 gtactgttca cggttctctt gcagctggtg ctatcacaac aacatttaca gcatcccagg
     1561 gtcttcttct tatgatccct aacatgtata agatcgcagc tgagcagctt ccatgtgtat
     1621 ttgatgtatc tgcacgtaca gttgctacac agtctctgaa cattttcggt gaccacagtg
     1681 acgtatatgc atgtcgtcag acaggatttg ctatgctggc agaaactaac ccacaggaag
     1741 ttatggactt aagccctgta gcacatcttg ctgcaatcga aggtaaagtt ccattcatca
     1801 acttcttcga tggtttccgt acatctcatg agattcagaa gatcgaaaaa tgggattatg
     1861 cagacttaaa agaaatgtgc aacatggatg cagttaaagc tttccgtgag catgctctta
     1921 acccagaaca cccagctatg cgtggttctc acgaaaacgg tgacgttttc ttccagcaca
     1981 gagaagcttg taactctgtt tacgaagctt taccagctgt tgttaagaaa tacatgggca
     2041 aaatcaacga aaaactggga actaactacg atttattcaa ctactatggt gcagaagatg
     2101 cagaccgcgt aatcatcgct atgggatcta tctgtgacgt agcagaagaa gtaattgatt
     2161 acttaacagc aaaaggtgaa aaggttggtt taatcaaagt tcgtttatat cgtccttggg
     2221 tatcttctgc attattagac gttattccta agacagctaa gaagattgct gttcttgacc
     2281 gtacaaaaga gcctggagca ttaggagatc ctttatatct tgatgttgct acaactctta
     2341 gagaagcagg tcttaacgat atcgttctta cagcaggacg ttacggatta ggttctaaag
     2401 atactcctcc ttcatctgta tttgctattt ataaagaact tgaaaaagac gctccaaaga
     2461 gccgtttcac aattggtatc gtggatgatg ttacaaactt atctttacca gaagttaaac
     2521 cagctcctat cacatctgct cctggtacag tagagtgtaa gttctggggt cttggtggag
     2581 acggtactgt aggtgctaac aagaactcta caaagattat cggtgaccac acagataaat
     2641 acattcaggc atacttccag tatgactcca agaagacagg tggtattaca atttctcacc
     2701 ttcgttttgg tgacaaccca atcagaagcc catactacat taatcaggct gacttcgtag
     2761 catgtcacaa cccatcttat gtagttaaag gttacaagat ggttcaggat gttaaaccag
     2821 gcggaatctt catgatcaac tgccagtggt ctgatgaaga attagatcat catatgcctg
     2881 cagcagctaa gaagtatatt gctgacaaca acattcagtt atacacaatc aacgcgattg
     2941 ataaggctat cgagattggt atgggtaaac gtactaacac aatcttacag tccgcattct
     3001 tcaaattagc gaacatcatg cctatcgatg acgcagtaga attcatgaaa gcagcagcta
     3061 agaagtccta cagcaagaag ggtgacgctg ttgtagagat gaactacaaa gctatcgacg
     3121 ctggtgtaga tgctgttcat aaagtagaga ttccagcttc ctggtctaac ccagctgctg
     3181 atgctcctgc taaagaactt acaggacgtc cagagacagt taagatggtt aaggaaatga
     3241 tggaacctat cggaatcatg gatggtgaca gcctgccagt atctacattc gtagacaacg
     3301 ctgacggaca gttcgaactt ggtgcttccg catacgaaaa acgtggtact gctgtatctg
     3361 ttccagaatg gaatccagaa gcttgtatcc agtgtaacca gtgtgcattt gtatgttctc
     3421 atgctacaat ccgtcctttc ttagtaagcg aagacgaaat taaggcagct cctgacaaca
     3481 tgaaagttgc agatacaaag ccaaaggcaa gcgaatacaa atttacaatg agcgtatctc
     3541 cattagactg tatgggatgt ggtgagtgta tcacagtttg tcctgctgca gctaagggcg
     3601 cattaaagat ggttccacag gaaagccagg cagcagaaca gccagtattc gattacttag
     3661 ttgcaactgt tggaagaaaa ccaggtgctc ctgccgatac tacagttaag ggatctcagt
     3721 tcaaccagcc attacttgag ttctccggat cttgtgcagg atgtgcagag acatcttacg
     3781 ctcgtctgat tactcagtta ttcggagagc atatgtacat ctccaacgca acaggatgtt
     3841 catccatctg gggtggtcct gcagcaacag ctccatatac agtaaacaaa gattccaaac
     3901 agggaccagc ttgggcaaac tccttattcg aggataacgc agagcacggc tttggtatgt
     3961 atcttggaca gaagacttta cgtgaccagg ctatcgctaa attagagaag atggcagcat
     4021 ccgataaagc atccgatgaa tttaaagcag catttgctaa gttcatggaa acaaaagaca
     4081 atacaaaaga aaatacacct gatgctcagg cattaatcgc tgaggtagaa aaagcagcag
     4141 cagctggatg cccagatgca gcagaagtat tagagaagaa acagtatctc gctaagaagt
     4201 ccgtatggat cttcggtggt gacggatggg catatgatat cggtttcggt ggattagacc
     4261 atgtattagc ttccggtgag aacgtaaacg ttatggtatt cgatactgag atgtactcca
     4321 acacaggtgg acaggcttct aaagcttcta acatcggtga ggtttgtcag ttcgcagcag
     4381 ctggtaaaga aatcagcaag aagagtcttg cagagatcgc tatgagctac ggatatgtat
     4441 acgttgcaca gatcgctctt ggtgctaacc ctaaccaggc agttaaatgt cttgcagaag
     4501 cagaagctta caacggacca tccctgatca tcggatacgc tccatgtgaa cttcacggta
     4561 tcgctaaggg tggtatgaac cactgccagg atgagatgaa gaaagccgtt aaggctggtt
     4621 actggaacct cttctccttc gacccagcta agaaagctga aggaaagaat ccattcacat
     4681 taacatctaa agaaggcgac ggatcatatc aggaattctt aaataacgaa tcccgttaca
     4741 ctcgtctgat taagccattc ccagaaagag ctgaaagact cttcaacgaa tctgagaagg
     4801 ttgctaaggc tcgttacgag cacctgcaga gactcgttga gctttataaa taataaagcc
     4861 tgaactggtc agtcagatta gttacaaaag ataaaacttt atgaaataca aaagagaagc
     4921 tatgtgtcag ctatgctgat gcatggcttc ttcttgtatg ttgaaaaaaa gaagggaatt
     4981 gtattataat aaatcataac aaattaatga ctgatagatg tactgacaat ggttttgaag
     5041 agggacagga atgctatata aagaagattt tggagaagga aaaaatatag aatttaaaag
     5101 agagataccg aaaagacatg agaagttatt aaaagatgtt attgcttttt ccaattctac
     5161 ggggggtaaa atttttattg gaattgagga taagacgaat gaagttattg ggattggaga
     5221 gaagaatcca tttagattag cagatgatat ttcaaatatg atatttgaca gctgcactcc
     5281 aataattgat ccggaaatta caatacagac attagaagga agaacagttg ttgttgtaga
     5341 agtttttcca ggacgtatgc gtccttatta tctcaagtaa tttgggaagg aacaaggttc
     5401 ttatataaga ataaatggta caagtcgtcc tgctgatgat agaaagttaa aggaactaga
     5461 attagaaggt caaaagattt cttatgatac tttaccggaa atagacatgg agtactcgga
     5521 acgagaggcg aagatattat gtaatgcaat ggaaaaagtg gcatatgatg tgcagacaac
     5581 atgtgtaaca agagcaatac aggaaacgtc attagatccc aagcaaaata cagaaaaaac
     5641 tgaaattata aataaaatga caatcgagaa actagaagac ttagggttat tgtgccgaat
     5701 aggaaaagac cttcaaccca cccatgcgtt tagactaatg acgaagaata aaatacggta
     5761 tgccaaaatt caatgtgcgt tatttaaagg aacagaaaga gatattttta tagataaaag
     5821 agaatttgat ggaccattat atgtacagct ggaaaatgct tatcaatttg tattaaagca
     5881 tatcaatctt ggtgcaaaga tagaagggtt acatagaaaa gaagcgtatg aactcccggt
     5941 tcgaacaata agagaattga ttactaatgc agttgttcat agaagttatt tggatgagtc
     6001 ctgtatacag gtttgtgtct atgatgacag gatagaagta acatctcccg gaatgcttta
     6061 tgggggactg gatatacagt cagctaaatc aggtaaatca aagtgcagaa atacagcgat
     6121 tgctgaagca tttcgttata tgggacttat agaagcgtgg ggaacaggaa tcccaagaat
     6181 gataaaagaa tgcagagaat atggattgag agagccagtg tttgaggaac tgggagatgg
     6241 tatacgagta actatattcc gggaaaatga agaattggag atgcgaaaac gggcggagaa
     6301 tatacagaac gctgaaaata aataccagta tatgaataat ataaatagtg agaacttagc
     6361 atctgtagta aaagaacaaa cagtggaata tagagagcaa aatcactgtt tcaatacaga
     6421 aaaatcactg tttaatgcgc tggattcaca aggaaatgaa aaaaaatact gtttgaatga
     6481 tgaaaaaaca ctgtttgaaa caacaagtca ggataaaacc cactgttttg aaacgtctgt
     6541 attgactgca gagaataaat atatgttata taaaaagctg gaagaactac aagttaataa
     6601 aagcataggt agcgtcactg cattaaatat aaaggagatt atcgaaagct tttcaggaga
     6661 agaagtcttt gggcgaaaag aaataaaaca aaaactagga tataaagaca gtaaggcggg
     6721 atttctgatt caaacaatgc gggaatttga gttgattaaa gctgtgaaag gaaggggcaa
     6781 gggaaagtat tgttttgata tttaaaactc tatcttggct ttcataagaa aatttaaagc
     6841 cgtacttctg tgaagaacgg atttaatgta taattgaaaa tagtattgaa taaaattata
     6901 tagaaggact attttaattt ttttgagcgt atagattttt ttactgtgga aatcaataca
     6961 aataaagtac taattacatc ataagcatca gataaattat cgtatgtatt ttttgtttta
     7021 agaaaaaact ttttaaaagt tgataaaagt tgagttgctt tttttgtgga taatgttaaa
     7081 tggaatttat tttgtttctt atatgtatta tatgtatttg tagcaacttt ctttttgtag
     7141 tttttaggat tacgttgctc ttggtttttg tttgtgtatt gttcttgtat ttcggataat
     7201 ttatttttcc ctttttggtg agaagatcca tcagaaatat ctaaaatact aacttgtaca
     7261 gtagggtggt aggtaggcgt tgggagagtg ttaatggtat taaatggcat acaaattaaa
     7321 gtggctatta taataagaga taaagtttta gaaattttag gtacaattga aagctgctta
     7381 gctttagctt ttttgttaga taaagcttta aaaatctttg aatctttttc taaagatttt
     7441 acagtgcaag ggactgtcgt tagagtatta ttaattgctt ttctattttc tggcgtgtta
     7501 gggattaaaa tataatcaga ttctagtttg ttgataagtt ccttgtagag tttttcataa
     7561 aatttgttaa taatcattgt gatttctcct ttcttttttc tataataata aatgcgtatt
     7621 tttttgcgaa atggcctctc ctttctgtat cgaatttcaa cattttttgt tgattattat
     7681 taatatgtat aattttttct ttttgtattg ctctgatttg ccatgtgtgt aattaaaatc
     7741 tcctttctta cattagtatg agagattagg gaaattttct ttttgaaaag atagtttacg
     7801 aaaaaagaat ccgattcttt tttcgctttt tcactacaaa tagtatgcta gagcgtgttt
     7861 gaaaaaccat tcctacaacc tgcacgcccc aatttgcggt atattttgcc ttcattcagt
     7921 tgacgtagcc cgctacgccg ccctcattca ggcaaaatct cccacaaatt gtaacgcaca
     7981 tcttgcagaa agcatttttc aaacacgctc tagtttagac aatggcataa aattgtagaa
     8041 ttcaaccaat tacttactta attttcttaa gttattttgt atacaatgtt aataaaatgc
     8101 aggatttata ttttaaaatt acatttataa ttgtatgaat tgtctttaaa tctgaaaata
     8161 acgatgaata aagaagtgaa atcacaaaca aaattgtact tttataagaa caatataatc
     8221 taaaaagaaa taaaaaccaa ataaactaac tacaatatcc cctaaaacaa gagcaataat
     8281 cagaaaataa tatattaaaa aataaataat caaattatta gacaactcac cttaatgttt
     8341 atatttacaa cctatttaaa atgttgtaat atgataacaa caaaaagaaa tgcaggaagt
     8401 cattacaact acttctgaaa atgaatttgt tactttttaa atatgtaatt attcagagat
     8461 ttatagattt ttattcagac tatagatact cattcaggat tatgaaatca taagattaca
     8521 agagcatgag aacatgagaa tcataaggtt tgattaagag ttcctgataa ttactaatta
     8581 caaaaatata atttacaact gatgaatatt tactatttca tagtgatgca agaaagggtg
     8641 agaccatgta tcaggacaat atgcgacagg gtctatatga tccaagtctg gagcatgata
     8701 actgtggtat tggtgctgta gtaaacatca agggtcttaa gagccatgag acagtatcga
     8761 atgccttgaa aattgttgaa aatcttgaac atagagccgg caaggacgcc gagggtaaaa
     8821 cgggtgacgg agtaggtatc ttagtgcaga tatcccataa gttcttcgaa aaaacctgta
     8881 gtactctcgg cttttctatt ggcaaggaac gtgactacgg tattggtatg ttctttatgc
     8941 cacaggatga gttacagaga aaccgtgcta agaagatgtt tgagattatc gttgaaaaag
     9001 aaggcttaaa tttcttaggc tggagagagg ttccggttca gccgggcatc ctcggaaaga
     9061 aagcagcgga ctgtatgcca tgcattatgc agggatttgt aaagagaccg tttgatgttc
     9121 cacgaggact tgacttcgat agaagacttt atattgtaag acgagtattt gagcagtcta
     9181 acgattctgc ttatgttgtt tctttaagca gcagaacaat cgtatataaa ggtatgttct
     9241 tagttggaca gttaagatta ttctataatg accttcagga taaggattat gaatctgcaa
     9301 tcgcattagt tcattcccgt ttctccacaa acacagttcc aagctgggag aaagcacatc
     9361 cttatcgtta catcgttcat aatggtgaga ttaatactat tcgtggtaat gccgataaga
     9421 tgttagcccg tgaggaaaac atggaatctg attatctgaa ggatgagatg attaagctga
     9481 caccagttgt agatccaaac ggttctgact ctgcaagatt agataataca ttagaattcc
     9541 tcttaatgag tggaatgcca cttcctctgg caatgatgat cacgattcca gaaccttggg
     9601 aaaataacga gggcatgagc agagagaaga gagacttcta tcagtactac gcaacaatga
     9661 tggagccttg ggatggtcct gcatctatcc tctttacaga tggagatatc atgggagccg
     9721 tacttgaccg taatggtctt agaccttccc gttactatat tacagatgat gaccagttaa
     9781 ttctttcttc tgaggttggt gtgttagact ttgacacaac acatatcgta aagaaagaga
     9841 gacttcaccc aggtaaaatg cttctcgtag atactgtaaa aggtgagctg attgacgatg
     9901 aaatcttaaa agattcttat gtaaagaatc agccttacgg tgaatggtta tccgataacc
     9961 ttgtattctt aaaagactta aagattccga atgttgcagt agaagaatac agctatgaag
    10021 agagcaaccg cctgatgaaa gcatttggtt actcttatga agaagtgaaa gattctgtat
    10081 taccgatggc attaaacgga agtgaagcaa tcggagcgat gggggttgat actccattag
    10141 cagtactttc taagagacat catccattat ttgattactt taaacagctt tttgcacagg
    10201 taacaaaccc tcctattgat gcgattcgtg aggaaatcgt tacatctact tccatctatg
    10261 ttggcggaga gggaaatgtg ttggaagaaa aggcagaaaa ctgccatgta ttaaagattc
    10321 acaaccctat tttaacaaat acagacttat taaagattcg ttatgcaaag gtaaagaata
    10381 tcaatgtaaa agatgtgccg attacttatt acaaaggaac accgcttgat aaggctatca
    10441 atcatttata tgttgctgtt gaccaggcgc ataaaaatgg tgcaaatgtt gttattttga
    10501 cagatagagg tgttgatgag aaccatgtgg caattccatc tctgttagca gtatctgctg
    10561 tacatcatca tctcattgag acaaagaaga gtacttctgt aagtattatc ttagagagtg
    10621 gtgagccaag agaagtacat cattttgcaa cactgttagg ttacggcgca tgtgctatca
    10681 acccatatct ggcacagttc agtattaaga agctgattca ggatggttta ttaaagaaag
    10741 attactatgc agcagtaaat gattacaata atgcagtact tcacggtatc gtaaagatcg
    10801 catctaagat gggtatttcc acactgcagt cctatcaggg ttctcagatt tttgaggcag
    10861 ttggtatcag caagaaagtc attgatgagt actttacaaa cacagtaagc cgtgtagaag
    10921 gtatcacaat tgaagatatc gcagaagatg tagattacca tcactccaaa gcatttgata
    10981 tgttaggact gaaaaatgat cttagtcttg acagtgaagg tgatcacaaa tatagaagtg
    11041 gtaaagaaga acatctttac aatccactga ccatccatac attacagaca gcagcatgga
    11101 caaataatta tgaactgttt aaacagtata cttccatgat taataaagaa acttctccag
    11161 taagtcttcg tggattaatg gatttcaatt atccatccaa aggagttcct atcgaagaag
    11221 ttgaatctgt agattctatc gtgaaacgat ttaagacagg tgctatgagt tatggttcta
    11281 tttccaagga agcacatgag actctggcaa tcgcgatgaa catgattcac ggtaaatcaa
    11341 acactggtga aggtggagaa gatttagagc gtctgacagt tggtccagat ggactgaata
    11401 aatgctctgc aatcaagcag gtagcttccg gtcgtttcgg tgtaacaagc cgttaccttg
    11461 taagtgcaca ggaaattcag attaagatgg cacagggagc aaaacctggt gaaggtggac
    11521 atttaccagc aggaaaagta tatccttgga ttgcaaagac aagacattca acacctggtg
    11581 taggtcttat ttcaccacca cctcatcacg atatttacag tatcgaagat ttagcacagt
    11641 taatttatga cttgaaaaat gcgaacaggg atgctcgtat ttctgtaaaa ctggtatccg
    11701 aagcaggtgt cggaacagtc gcagccggtg tagcaaaagc tggtgcacag gtaatcctta
    11761 tttccggaca tgacggaggt acaggtgcag cacctcgtaa ttcttccatt cataatgccg
    11821 gacttccttg ggagcttgga cttgcagaaa cacaccagac attaattaaa aatgaccttc
    11881 gtaataaagt tatcatcgag acgg
//
