LOCUS       c00039_gnlPro..         9221 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HEKCBFPP_39.
ACCESSION   c00039_gnlPro..
VERSION     c00039_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:46:57
            Original ID  :: gnl|Prokka|HEKCBFPP_39
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9221
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9221
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3063:9181]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3064..9181
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..9221
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9221
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="acetate2butyrate"
                     /region_number="1"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             complement(2..1036)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AcetylCoA_hyd_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AcetylCoA_hydro"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_1"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 7.5e-15,
                     bitscore: 44.6, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 4e-31, bitscore:
                     97.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VVEYTHDIFLTRAEVVRRRSMSFIKEYAQKLVTAEEAVKVVKSHD
                     WVDYGWTTGTPVALDAALAARADELEDVKIRGGILLREPEIFKVNNVADHFTWNSWHMG
                     GLERKAISKGFAYYSPLKYSELPRYYRENIKHLNVAMFQVAPMDKHGFFNFGPNASHMM
                     AVCEAADVIIVEVNENMPRCLGGFEEGIHVSRVDYIVEGENPAIGELGAGAPPTEVDKA
                     VAQLIVEEIPDGACLQLGIGGMPNTVGSMIAESDLKDLGVHTEMYVDAFVDIAKAGKIT
                     GLKKNIDRGRQVYAFGAGTKKMYDYLDDNPECMSAPVDYTNSAKTIAQIDNFISINNAV
                     DIDLY"
     CDS             complement(1085..1801)
                     /locus_tag="ctg39_2"
                     /transl_table=11
                     /translation="MLSVMIFCHDKREGDLIGNICNQCVALIGKEFLRNFIISDGEYHQ
                     VNIEGIQPPDLLVVEITGIEDLCRAKRIRGIFPRGRLLVVSTNQISAESYLIPEVSPDT
                     LLLKPYVYAKACRIIYRSLTWCCKDKCRKKKQEDILKIRTGGEIYYFHYEEIQYLEARD
                     KKIILHVNQYEISFYSSLQKLEKSLPDYFIRCHRSYIVNFMFIQKADLINGEFYLNKKT
                     VIPISQKYKAKLAKML"
     CDS             complement(1826..2143)
                     /locus_tag="ctg39_3"
                     /transl_table=11
                     /translation="MADLINVTPEKLKATASSFQQAGKDVKKTTSDMLQLVRGISSSIW
                     SGEASSIYLGKFNGLDADIAKMCKMIEEESQHLTTIAQEYQLAEEQNKQVAATLKNNVI
                     A"
     CDS             complement(2155..2445)
                     /locus_tag="ctg39_4"
                     /transl_table=11
                     /translation="MAQIIASTKEISNNRESLIVLINSLKNKISLLETLGNSLNSMWEG
                     AAKEKYVKQLKTDISKMRNLLKTILEFILILEKIIAIYNKAEKKNEATAVS"
     CDS             complement(3064..4104)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 167.1;
                     E-value: 1.2e-51)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_5"
                     /sec_met_domain="ETF (E-value: 2e-52, bitscore: 167.1,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 5.8e-39, bitscore:
                     121.6, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNRMNLEQYKGVFIYAQQVDNKIDAIALELLGKANDLAADLGTDV
                     TAVLIGSDVKGLVDELAEYGADKVIVVDDPELKEYRTEPYTHALASVINEYKPDILLVG
                     ATAIGRDLGPRVSARVATGLTADCTVLEIGEFKARGDKEPRQGQLLMTRPAFGGNTIAT
                     IACPNHRPQMATVRPGVMQKKEPVAGAKAEVIEYNPGFTPNDKYVEILDIVKSVTETVD
                     IQAAKILVSGGRGVGSAENFALLDDLAEALGGTVSCSRAVVDNGWKPKDLQVGQTGKTV
                     RPNVYFAIGISGAIQHVAGMEESDIIIAINKDPDAPIFDVADYGIVGDALKIVPKLTEA
                     IKAQVK"
     CDS             complement(4121..4906)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 163.8;
                     E-value: 1.3e-50)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_6"
                     /sec_met_domain="ETF (E-value: 2e-51, bitscore: 163.8,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIVVCVKQVPDTKGGVKFKPDGTLDRAAMLTIMNPDDKAGLEAA
                     LRIKDETGAEVTVVTMGLPKAEEVLREAMAMGADKGILVTDRVLGGADTWATSTTIAGA
                     LRNIDYDLIITGRQAIDGDTAQVGPQIAEHLDLPLISYAQDIKVEGDSVIVQRQYDDRY
                     HVLKAKMPCVITALSELNEPRYMTPGGIFDAYDAEITTWGRKDLKDVDDSNLGLAGSPT
                     QIAKASDKVRKGKGVMMTAETAEEGVEYIMDKLLTKHVI"
     CDS             complement(4921..6075)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_7"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.3e-52, bitscore:
                     167.5, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.8e-31, bitscore:
                     96.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.3e-41, bitscore:
                     131.3, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFTLSKKHEMARQLFKEFAENEVKPLAQEVDETEHFPEETVAKM
                     QKLGFMGIPVPKEYGGQGCDPLTYIMCVEELSKVCGTTGVIVSAHTSLCADPILTYGTE
                     EQKQKYLVPLAKGEKLGAFGLTEPGAGTDAQGVQTKAVLDGDEWVLNGSKCFITNGSYA
                     DYYIIIAITSVDTDARGRKKKKFSAFIVEKGTPGFTFGTKEKKMGIRGSATYELIFQDC
                     RIPKENLLGPMGKGFAIAMHTLDGGRIGIAAQALGIAEGALDATIAYVKERKQFGRAIA
                     AQQNTQFQLANMATQVEAAKLLVYKAAMAKATQRVYSVEAAKAKLFAAETAMDVTTKCV
                     QLLGGYGYIREYDVERMMRDAKITEIYEGTSEVQRMVISGNLLK"
     CDS             complement(6176..7015)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_8"
                     /sec_met_domain="HCDH (E-value: 6.3e-39, bitscore: 122.1,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 5.5e-62, bitscore: 198.3,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGVIGAGTMGSGIAQAFAQTEGYEVYLCDINDEFAANGKKKIA
                     KGFEKRVARGKMDQAKADAILAKITTGTKDICTDADLVVEAALEVMEVKQQTFKELQDI
                     VPATCMFATNTSSLSITQIGAGLDRPVIGMHFFNPAPVMKLIEVIAGLNTPDEMVEKIK
                     AISVEIGKTPVQVEEAAGFVVNRILIPMINEAVGIYADGVASVEGIDTAMKLGANHPMG
                     PLALGDLVGLDICLAIMEVLYNETGDPKYRPHPLLRKMVRGGKLGQKTGIGFYDYSK"
     CDS             complement(7084..7869)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: EC1_2-faecali"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_9"
                     /sec_met_domain="EC1_2-faecali (E-value: 9.7e-92, bitscore:
                     296.2, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFIDYEVDGQVGIITINRPKALNALNSEVLKDLDATIDAVDLDA
                     IRCLIITGAGEKSFVAGADIGEMSTLTKAEGEAFGKAGNDVFRKIETLPIPVIAAINGF
                     ALGGGCEISMSCDIRLCSENAVFGQPEVGLGITPGFGGTQRLARIVGPGKAKQLIYTAR
                     NIKAAEAYRIGLVNEVYPLEELMPQAKKMAKGIAKNAPIAVRACKKAINEGLEVGMDEA
                     IVIEEKLFGSCFETEDQKYGMAFFLDKNKEKVKEPFKNC"
     CDS             complement(8000..9181)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_10"
                     /sec_met_domain="Thiolase_N (E-value: 3.1e-104, bitscore:
                     337.3, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 3.9e-51, bitscore:
                     161.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKVVLAGACRTAIGTMGGGLSTVPAADLGSIVIKEALKRTNVP
                     ADQVDEVLMGCVIQAGLGQNVARQASINAGLPIEVPAVTINVVCGSGLNCVNLAATKIL
                     AGEADIVIAGGMENMSLAPFCLDKARFGYRMNNGVLKDCMVNDALTDAFNQYHMGITAE
                     NVAEQWHLTREELDEFSANSQQKATAAIEAGKFKDEIVPVEVKLKKKTVVVDTDEGPRP
                     GTTAESISKLRPAFKKDGIVTAANSSGINDGAACVVVMSEEKAKELGVTPMATWVAGAL
                     GGVDPSIMGVGPVASTKKVLAKTGMSIDDFDLIEANEAFAAQSLAVGRELGINPEKLNV
                     NGGAIALGHPVGASGCRILVTLLHEMQKRDAKKGLATLCIGGGMGCSTIVERD"
ORIGIN
        1 catataagtc aatatcaact gcattattga tagaaataaa gttatcaatc tgtgctattg
       61 tcttagcgct attcgtataa tcaactggtg cactcataca ttctgggtta tcatccagat
      121 aatcatacat cttcttagta cctgcaccga atgcatatac ctgacgtcct ctgtcgatat
      181 tcttctttaa gcctgtaatc tttcctgcct ttgcaatgtc aacaaacgca tcaacgtaca
      241 tctctgtatg tacacctaag tcctttaaat cagattcagc aatcatggaa cctactgtat
      301 taggcattcc accgatacca agctgtaaac atgctccatc tggaatctct tctacgataa
      361 gctgtgctac ggctttgtct acttctgttg gtggtgcgcc agctcctaac tcaccgatag
      421 ctggattctc gccttctacg atgtaatcta cgcgagaaac atgaatgcct tcttcaaatc
      481 cacccagaca gcgaggcata ttctcattaa cctctacgat aattacatct gcagcttcac
      541 aaactgccat catatgggat gcatttggtc caaagttaaa gaatccatgt ttatccattg
      601 gagcaacctg gaacatcgca acattcaaat gcttgatatt ctctctgtaa taacgtggaa
      661 gttctgaata ttttaatgga gaatagtatg caaatccttt actgattgcc tttctctcca
      721 aaccacccat atgccaggaa ttccatgtaa aatgatctgc tacattattt accttgaaaa
      781 tctctggttc tcttaataag ataccaccac gaatcttaac atcttctaat tcatctgctc
      841 tggctgctaa tgctgcatcc aatgcaactg gagtaccggt tgtccaacca taatctaccc
      901 aatcatgaga ttttactacc ttaaccgctt cttctgctgt aacaagtttc tgtgcatatt
      961 ctttaatgaa actcatgctt ctcctcctaa caacttctgc tcttgttaaa aaaatatcat
     1021 gagtatattc taccaccgtt gtataactcg gtcaacctaa atcgaacctt gaatccttat
     1081 atttttacaa catttttgct aatttggcct tatatttctg agaaattgga ataactgtct
     1141 ttttattcaa ataaaattca ccatttatca aatctgcttt ttgaataaac ataaaattca
     1201 caatataact acgatggcaa cgaataaaat aatctggcag gctcttctcc aacttttgca
     1261 aggaactata aaaagaaatc tcatactgat ttacatgcaa gataatcttc ttatctcttg
     1321 cttctaaata ctgaatctct tcataatgaa aataataaat ctcccctcct gtccgaatct
     1381 ttaatatatc ttcttgcttt ttctttctac acttatcctt acaacaccat gtaagacttc
     1441 ggtatataat cctacaagct ttcgcatata catatggttt cagtaaaagc gtatctggtg
     1501 aaacttccgg aattaaatag gactctgctg aaatctgatt agtacttaca actagcaatc
     1561 gtcctctcgg gaaaatcccc cttattcgtt tcgctctgca taaatcctct atacctgtga
     1621 tttctactac aagtaaatct ggcggctgta ttccctctat attcacctga tgatactctc
     1681 catcgcttat gataaaatta cgtaaaaact ctttacctat aagcgccaca cactgattac
     1741 atatatttcc aattaaatct ccttctcttt tgtcatgaca aaaaatcata actgacagca
     1801 taatctattc atctgtctat acaatctaag caattacatt attctttaat gttgccgcaa
     1861 cctgtttatt ctgttcttct gctaactggt attcctgtgc aattgttgtc aaatgctgtg
     1921 attcttcttc tatcatcttg cacatcttgg cgatatcggc atccaatcca ttaaacttac
     1981 caagatatat actactcgcc tctccactcc agatggaact actaattccc ctcactaact
     2041 gaagcatatc agaagtagtt ttcttaacgt cctttcctgc ctgttggaaa gaacttgctg
     2101 tcgcctttaa cttctctgga gttacattaa ttaaatctgc cataaatccc cctcctagct
     2161 taccgctgtc gcctcattct tcttctccgc tttattatag attgcaataa tcttctctag
     2221 tatcaatata aattccaaaa ttgtcttaag taagttccgc atctttgaaa tgtctgtctt
     2281 aagttgcttt acatacttct cttttgcagc gccttcccac atagaattaa gactgttccc
     2341 caaagtttct aaaagcgaaa tcttattctt taaagaatta atcaatacta tcagtgattc
     2401 tctattatta gatatttctt ttgttgaagc aataatttgt gccataaatg cctcctctca
     2461 tatctcggtt aactgccgca agagtattat aacatatttg ggattaattt ccactatttt
     2521 tgacaaatta tgtttatttt gtgataagta cttctttatt atgtttactt tttattatat
     2581 ataaaataaa aatgacgtat tttactagag cgtgtttgaa aaatgctttc tgcaagatgt
     2641 gcgttacaat ttgtggaaga ttttacctga atgagggcgg cgtagcgggc tacgtcaact
     2701 gaatggatgc tatactagag cgagtttgaa aaatgctttt gcaagatgtg cgttacaatt
     2761 tgtggggaat ttttcctgaa tgaagacggc gtagcgggct atgccaactg aatgaaagta
     2821 aaaaagacca cagttataaa ctgtagtctt actatctcac tttaacaggg aatcttcaaa
     2881 aagattccct gaataaatac attttataga gttcagcaca aatctcctat atgcttcttt
     2941 taataatgaa tcgtcaatac acaaaacatc tgagaatgca tatactagac ttccacaaaa
     3001 aatctaagtt taaatcctca atcagtaact cacataatct aatgagtctg atatgatttg
     3061 aaattattta acctgagctt tgattgcctc tgttaactta ggaacaatct ttaatgcatc
     3121 gccaacaata ccgtaatcag ctacatcaaa gataggtgca tctgggtctt tattgatagc
     3181 aatgatgata tcagattctt ccataccagc tacgtgctgg atagctccgg aaataccgat
     3241 tgcaaaataa acattaggac gaactgtctt accagtctga ccaacctgta aatcttttgg
     3301 tttccatccg ttatcaacaa ctgcacgaga acaggaaact gttccgccaa gtgcctctgc
     3361 taaatcgtct aataatgcaa agttttcagc agaaccaact ccacgtccgc cagatacaag
     3421 aatcttagca gcctggatat caactgtttc tgtaacagat tttacaatgt caagaatctc
     3481 aacatatttg tcatttggag taaatcctgg attgtactca ataacttctg cctttgcacc
     3541 tgcaacaggc tctttcttct gcataacacc aggacgaact gtagccatct gtggacgatg
     3601 gttaggacaa gcgattgtag cgattgtgtt accaccgaat gcaggacgag tcattaataa
     3661 ctgaccctga cgaggttctt tatctccacg agctttgaat tcaccaattt caagaacagt
     3721 acagtctgct gtaagacctg ttgcaactct tgcagaaaca cgaggtccta agtcacgacc
     3781 gattgctgtt gctccaacca gaagaatgtc cggtttgtat tcgttgataa cagatgccag
     3841 tgcatgtgta tatggctctg ttctgtattc ttttaattca gggtcatcaa ctacgataac
     3901 tttatctgcg ccgtattcag caagttcatc aactaagcct tttacgtcag aaccgattaa
     3961 aactgctgtt acgtctgttc ctaaatctgc agcaaggtca tttgcttttc caagtaattc
     4021 taaagcaatg gcatcaatct tattgtcaac ctgctgagca tagataaata cacctttata
     4081 ttgttctaaa ttcattctat tcaccacatt tcctttacaa ttagataaca tgctttgtta
     4141 acagtttgtc catgatgtac tcaacgcctt cttctgctgt ttcagctgtc atcatgacac
     4201 ctttaccttt acgtacctta tcagaagctt ttgcgatctg agttggagaa cctgcaagac
     4261 ctaagttgct gtcatcaaca tctttaaggt cttttcttcc ccatgtagta atttctgcat
     4321 catatgcatc aaagattccg cctggagtca tataacgtgg ctcatttaat tcggaaagtg
     4381 ctgtgataac acatggcatt ttagctttta aaacatgata tctgtcgtca tactgtctct
     4441 gaacgattac actgtcacct tcaactttga tatcctgagc gtaggaaatt aaaggaagat
     4501 ctaagtgttc agcaatctga ggtcctacct gagcagtatc accatcgata gcctgacgac
     4561 ctgtgatgat taaatcataa tcaatatttc taagtgctcc ggcgattgtt gtagatgttg
     4621 cccatgtatc agctccacct aaaacacgat ctgtgacaag aattccctta tcagcaccca
     4681 ttgccatagc ttcacgcaga acttcttctg cttttggaag acccatagta actactgtta
     4741 cttctgcgcc tgtttcatct tttattctaa gggcagcttc aagacctgcc ttatcatctg
     4801 gattcatgat agtaagcata gctgctctat caagagttcc gtctggttta aacttaactc
     4861 caccttttgt atcaggtacc tgtttaacac atactacgat tttcacagta ttttccctcc
     4921 ttatttcaat aagttaccag aaataaccat acgctgaact tctgatgttc cttcgtagat
     4981 ttctgtgatc ttagcgtcac gcatcatacg ttctacgtcg tactctctga tgtaaccata
     5041 accaccaagt aactgaacac acttagttgt tacatccata gctgtttctg ctgcaaataa
     5101 tttagctttt gcagcttcta cggagtatac tctctgtgtt gcttttgcca ttgctgcttt
     5161 ataaacaagt aacttagcag cttctacctg tgtagccata ttagcaagct ggaactgtgt
     5221 attctgctgt gcagcaattg ctctgccaaa ctgttttctt tctttaacat aagcaattgt
     5281 agcatctaaa gcaccttctg caataccaag agcctgagct gcaataccga tacgtccacc
     5341 atctaatgtg tgcatagcga ttgcgaaacc tttgcccata ggtccaagaa gattttcttt
     5401 aggaatacga caatcctgga aaatcaattc atatgtagct gaaccacgga tacccatttt
     5461 cttttctttt gtaccaaatg taaatcctgg agttcctttt tctacgataa atgcggagaa
     5521 tttctttttc tttcttcctc ttgcatctgt atcaacactt gtgatagcga tgataatata
     5581 gtaatcagca taagaaccgt tagtgatgaa acatttagat ccgtttaata cccattcgtc
     5641 accatctaaa acagcctttg tctgaacacc ctgagcgtca gtaccagcac ctggctctgt
     5701 aagaccgaaa gcacctaact tttcaccctt tgcaagtgga acaagatatt tctgtttctg
     5761 ttcttcagta ccgtaagtaa gaattggatc tgcacacaat gatgtatgtg cggatacaat
     5821 aacacctgtt gtaccacaaa ctttagataa ctcttcaaca cacataatgt atgttaaagg
     5881 atcacagccc tgtccgccat attcttttgg cacaggaatt cccatgaaac ctaatttttg
     5941 catttttgca acggtttctt ctggaaaatg ttctgtctcg tcaacctcct gagcaagagg
     6001 tttaacttcg ttttcagcga actctttaaa gagctgtcta gccatttcat gctttttgct
     6061 taatgtgaaa tccattttca ttcctccata ataaattggt tattggggtg gagaaccacc
     6121 ttaaaagccg tggagacgca gagcatagtc cccacggccg tattcacttt tttaattatt
     6181 tgctgtaatc gtagaatcca ataccagtct tctgacctaa ttttccacca cgaaccatct
     6241 ttcttaataa tggatgtgga cgatacttag gatctcctgt ttcattatat aatacttcca
     6301 tgattgcaag gcagatatca agaccaacta aatctcctaa agcgagaggt cccattggat
     6361 ggttagcacc taacttcata gctgtgtcga taccttcaac agaagcaaca ccatcagcat
     6421 aaatgccaac tgcttcgtta atcattggga ttaagattct gttaactacg aatcctgcag
     6481 cttcttctac ctgtacaggt gttttgccga tttctacgga gatagcttta atcttttcaa
     6541 ccatttcatc tggtgtatta agaccagcga taacttcaat taatttcata actggagctg
     6601 ggttgaagaa atgcattccg ataactggtc tgtcaagtcc tgcaccaatc tgtgtaatag
     6661 ataaagaaga tgtatttgtt gcaaacatac atgttgcagg aacgatatcc tgtaattctt
     6721 taaatgtctg ctgtttaact tccataactt caagagctgc ttctactact aaatcagcat
     6781 ctgtacagat atcttttgta cctgtagtga ttttagcaag gattgcatca gctttagcct
     6841 gatccatttt tcctcttgct actctctttt caaatccctt agcgattttc tttttaccat
     6901 ttgcagcaaa ttcatcgttg atatcacata aatatacttc gtatccttct gtctgtgcga
     6961 atgcctgagc aatacctgat cccattgtac ctgcgccaat aactccaact ttcattgttt
     7021 gaaacctcct ataaaatgta atgtattccg ataattaata atacaatatg tataattgat
     7081 taattagcag tttttaaatg gctcttttac tttttctttg tttttgtcaa ggaagaatgc
     7141 cattccgtat ttctggtctt ctgtctcgaa gcagctgcca aataacttct cttcgattac
     7201 gatagcttca tccattccta cttctaaacc ttcgttgata gctttcttac atgcacgaac
     7261 tgcgataggt gcgttctttg caataccctt tgccatcttc ttagcctgag gcattaactc
     7321 ttcgagtgga taaacttcgt taaccagacc gattctgtaa gcttctgctg ctttaatatt
     7381 gcgagcagta tagattaact gttttgcttt tccaggtcct acgatacgag caagtctctg
     7441 tgttccacca aaacctggtg tgattccaag accaacttct ggctgtccaa atactgcatt
     7501 ctcagagcaa agtctgatgt cacagctcat agaaatctca cagccaccgc ctaaagcgaa
     7561 tccgttgatt gctgcgataa cagggattgg aagtgtttca atctttctga atacatcatt
     7621 accagcttta ccgaaagctt cgccttctgc ttttgtaagt gtactcatct ctccgatatc
     7681 agcacctgct acgaaagatt tctctccagc accagtaatg ataagacatc tgattgcgtc
     7741 taaatctact gcatcaatag ttgcatctaa atcttttaat acttcactat ttaaagcatt
     7801 taaagccttt ggacgattga tggtgataat accaacctgg ccatctactt cataatcgat
     7861 aaatcccatt gtatgtatct cctttcagat tacattagct aactattcaa tctagataat
     7921 taaatagtta caaactatgt aattgatata accggattcg aaaaccgaac ccggatatat
     7981 gtaatcattc tatacgtgat tagtctcttt caacgattgt tgagcagccc ataccaccac
     8041 cgatacacag tgtagcaaga cctttcttag catcacgttt ctgcatctca tgtaataatg
     8101 taacgaggat acggcatcct gatgctccta ctggatgtcc aagagcaata gctccaccat
     8161 taacatttaa cttctctggg ttgattccta attctcttcc tactgctaat gactgagctg
     8221 cgaaagcttc gttagcttcg attaagtcaa agtcatcaat gctcatgcct gtttttgcaa
     8281 gaactttctt agtagaagca actggtccaa cacccatgat agaaggatca actccgccta
     8341 atgctcctgc tacccatgta gccattggag ttacacctaa ttctttagct ttttcttcgc
     8401 tcataacaac aacacaagca gcaccatcgt taatacctga agagttggca gctgttacga
     8461 taccatcttt cttgaaagca ggacgtaatt tagaaatact ttctgctgtt gttccaggac
     8521 gtggtccctc atctgtatct acaacaactg ttttcttttt aagtttaact tctacaggaa
     8581 caatctcatc tttgaactta ccagcttcga tagctgctgt agctttctgc tgtgaattag
     8641 cggagaactc atctaactct tctcttgtta aatgccactg ttctgcaacg ttttcagctg
     8701 taatacccat atggtactga ttgaaagcat ctgttaatgc atcgttaacc atacagtctt
     8761 ttaatacgcc attgttcatt ctgtatccaa aacgagcttt gtctaagcag aatggagcta
     8821 atgacatgtt ttccatacca ccagcgataa cgatatcagc ctcacctgct aaaatctttg
     8881 tagcagcaag gttaacacag ttaagaccgg aaccacaaac tacgttaatt gttacagcag
     8941 gtacttcgat tggtaagcct gcattaatag aagcctgacg agcaacgttc tgtccaagac
     9001 cagcctggat aacacatccc attaatactt cgtctacctg atcagcaggt acgttagttc
     9061 tctttaacgc ttctttaatt acgatgcttc ctaaatctgc agctggtact gtgcttaatc
     9121 caccacccat tgttccgatt gcggtacgac aagcacctgc taatacaact ttctttgcca
     9181 tagtttcatt cctccattta agttatcaat attatttgat a
//
