LOCUS       c00007_gnlPro..        15702 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OFPHCHLL_7.
ACCESSION   c00007_gnlPro..
VERSION     c00007_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:11:54
            Original ID  :: gnl|Prokka|OFPHCHLL_7
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 118043
            Orig. end    :: 133745
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15702
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[128043:131671]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13628
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..15702
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15702
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             complement(114..866)
                     /locus_tag="ctg7_101"
                     /transl_table=11
                     /translation="MGEKFNISNLNLYYGDFHALKDVDLSINEKEITAFIGPSGCGKST
                     FLKCLNRMNDLVQGCKITGQVLLDGEDIYSGMDVNLLRKRVGMVFQKPNPFPMSIYDNI
                     AYGPRTHGIRSKAKLDEIVEKSLRDAAIWDEVKDRLKKSALGMSGGQQQRLCIARALAV
                     DPEVILMDEPTSALDPISTSKIEDLAVELKKKYTIIMVTHNMQQAVRVSDKTVFFLLGE
                     VIESGDTEKLFSVPQDKRTEDYITGRFG"
     CDS             complement(892..1770)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 87.9; E-value: 2.3e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_102"
                     /sec_met_domain="BPD_transp_1 (E-value: 4.1e-27, bitscore:
                     87.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQINPINKVTLKDKMKSYTRHPGSLILLLLVLIAAALTVVTLLF
                     LVDYILISGIPYLKPSLFALHYNSDNVSMLPAIINTVEMVVVSLLFSVPFGVGAAIYMI
                     EYARKGNKFVEVVRLTAETLTGIPSIIYGLFGMLFFNIALHWRYSMLSGAATLAIMVLP
                     TIMRTTEEALLCVPDSYREGSFGLGAGKLRTIFKIVLPAAIPGILSGIILSIGRIVGET
                     AALIYTAGTVTGVAGLMDSGRTLAIHMYVLSNEGLHKNEANATAVVLLVIVLLINGVSS
                     LIAKRFEAVKE"
     CDS             complement(1774..2625)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 79.8; E-value: 7.3e-25)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_103"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.3e-24, bitscore:
                     79.8, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKREKIMEYVFLLAAVISIVAVALICIFLFANGIPAMKKIGFAE
                     FLTGTKWKPGNNKFGIFPMILGSIYVTGGALIIGVPVGVLTSIFMARFCPEGLYKLLKP
                     VVNLLAGIPSIVYGFFGLVVLVPFIREHFKNSNGQSILCASILLGIMILPTIIGASEPT
                     IRAVEQSYYEGALALGATHERSVFTVVVPAAKSGILAAVILGVGRALGETMAVMMVVGN
                     QPRVPNSILQGVRTLTTNIVMEMGYATDLHREALIATGVVLFAFILIINLCFSAIKRSG
                     KE"
     CDS             complement(2737..3705)
                     /locus_tag="ctg7_104"
                     /transl_table=11
                     /translation="MKKKVMCMLLTGVMAAGMFAGCGSSDTADTTTDAAATTDAASTAD
                     AADTTSEAAPAENADFDHTSAIAVYSREDGSGTRGAFIELFGVEEKDESGEKVDNTTEE
                     AIITNSTDVMLTSVAGDTYAIGYVSLGSLNDTVKAVKIDGAEATVENIKSGTYKIARPF
                     NIATKGEVSEAAQDFINYIMSGDGQKVISDNGYIGDDSAAAFESNGAEGKVVVGGSSSV
                     SPVMEKLIEAYKAVNANVEIELQTSDSTTGMTGAADGTLDIGMASRELKDSETEEGLIA
                     TKIAMDGIAVIVNQENPVEDLSSDTVKGIFTGGTTTWDAAN"
     CDS             complement(3842..4537)
                     /locus_tag="ctg7_105"
                     /transl_table=11
                     /translation="LPKNDSKKKKKRIEIKEKQNGEQKLPNEDLLSEKLLQPMVQLSYA
                     AAMDLVQARLRLINADLTEQCHRQVIRNMSCRIKTPDSVTKKLKKKGREVSFEEAVQTL
                     NDIAGIRVVCFFCDDIYRIADAIKKQKDFHIIKEKDYVKNPKKSGYQSIHVIAGVPVTY
                     NDTVTEIRVEIQIRSFAMDYWAELDTQMCYKKDAGQIANVERETRGYSDVIAKVDNKML
                     ELRQQIEMM"
     CDS             complement(4524..5813)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 79.2; E-value: 9.5e-25)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_106"
                     /sec_met_domain="MFS_1 (E-value: 1.7e-24, bitscore: 79.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKMSRLEKFWVLYDVGNSAFTLLVSTIIPIYYKNMASANGISA
                     SDSTAYLSYAISISTLIVAVLGPVLGAVADNKNRKKPLFTFFMMMGVLGCAALAIPRTW
                     ILFLAIFVIAKVGFSGSLIFYDSMLVDVTTDERMDEVSSQGYAWGYIGSCVPFVASLGL
                     ILGADAIGISGTVAMMIAFFINAAWWVVVTLPLLRNYQQKYYVEAGGTDVRGIFSRLGK
                     VFAEIRDDKKVLWFLAAFFFYIDGVYTIIEMATSYGKDVGISDTSLLMALLLTQVVAFP
                     CAILFGKLTQRFASSKLISVCIGAYFVVAVYALWLDAAWKFWMMATFVGVFQGAIQALS
                     RSYYAKIIPKEKSTEYFGIFDIFGKGASFMGTMLMGITTQLFDTSRAGVAAIAAMFVVG
                     FICFQMQRRCMEGETSQSGAMGGAAGFAKE"
     CDS             complement(5794..6807)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hydrolase_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_107"
                     /sec_met_domain="Hydrolase_4 (E-value: 9e-47, bitscore:
                     152.2, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPENKKRAGAEDAGYAAWMAETVEPYLKEHGEKGYLKMEDGMSI
                     AYRRYSLPDAGKCVVISHGFCEFAEKYNEVAYRFLQEGYSVYVPEHRGHGYSGREVDDP
                     ELVHVQSYDRYVTDFARFVETVVSPREEHRIVFAHSMGGAIAILALERYPQLFEAAVLS
                     APMCAMQTGKYPRFAARLLAEFCCLAGKGKCFATLAGQQGFSEAPQFEGSSCLSRERYD
                     YMFQKRLLEEHYRTYGGSYAWVRAGFRASRELMRRENLAKIKVPVLLFAAGCDHMVDNG
                     AIGRFAEETERTKLFSMPDSRHEIFNADERTRVKYYDEIFRFIKEEEVKDYENKNE"
     CDS             complement(6804..7604)
                     /locus_tag="ctg7_108"
                     /transl_table=11
                     /translation="MEKQTLVWAHRGASGYAPENTLEAFRKAVEMGADGVELDVQLTKD
                     GELVVIHDETVDRTSDGSGWVKDFTYARISRFNYNRTHKEGYERAMIPTLEEVYELLKP
                     TGLTINVELKTGVVFYPEIEERVLDLTARMGLEERVWYSSFNHYTVQRIKELNPQAKTG
                     MLYCDGIVNPVSYGALVVGADAMHPALYNLQYSNYMEDCKKHGKRVHVWTVNEEQYMRM
                     VCEMQVDAMITNYPDTGRRIAAEYVDGKLTPELVRVIKKQGNQA"
     CDS             complement(7724..8638)
                     /locus_tag="ctg7_109"
                     /transl_table=11
                     /translation="MENTTEERMENTTETRMGGMDMSDKKMNAESLRGTVCVLLSAVCF
                     STGGVLIKSIPWSSVTIQGARSIFSVLVVGCYMLLRRQKFVWNKTVLFGAVCNTVMAFA
                     FVAATKLTTAANAIVLQFTEPVFVILLMWLIFHKKPGRDSVFACAGVFAGILCFFYTSL
                     DAGAMAGNLLAILSGLAYALVMMQKKFRGADFESSLLVSCALSAAIGIPFYGQESEMSL
                     HIWFFVLLLGVVQFGLSYVFLSRGLDAVSPVTASLTSTIEPILNPILVAVFYGETIGAT
                     AVIGALLVVGSATAYNVRQAKNA"
     CDS             complement(8682..9809)
                     /locus_tag="ctg7_110"
                     /transl_table=11
                     /translation="MLQKITDFIKKETVLTIATAFAVASAFWVHPGPQYVGYIDWRVLG
                     ILLSLMLIVAGFQSNGLFDAIGSRLLAKTKNTAQLMLVLVFLCFFSSMFITNDVALLTF
                     VPFACTILQKCHQERLIVTTFVLQTLAANLGSMLTPVGNPQNLYLYSVSGAGLGEFIGW
                     MAPYTLVSGVLLLLVVFVLSAGKRRISLETGALLQTSGAAGRKKNGIYLALFVLSLLSV
                     ARVLPWELMLAVVLIVLIFTDRAVFLQVDYCLLFTFISFFIFIGNMGNIEAVRSVLQSL
                     VAGRELAVGIGASQIISNVPATLLLADFTHNLKNLTIGVNLGGLGTLIASMASLISYKI
                     YAHNYNKTKGRYLLWFTIANVLFLAVLVLVYVFIS"
     CDS             10001..11092
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_111"
                     /sec_met_domain="POR (E-value: 4.3e-25, bitscore: 81.6,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_7 (E-value: 7.7e-09, bitscore: 29.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 9.5e-08, bitscore: 24.6,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0011, bitscore: 12.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNTLSLPVTNENGSYEIRLESIGGLGANLCGKMLGELGALSLSL
                     NSLSFSSYGSEKRGSPVKAYVRWCADDRPLRVNSPVTRPHLLGIFHEGLIGTYPVLDGV
                     TVDTKIVLNTPLSADEAADKYHISIGELYCLDALALAMESHSRINMVMLGALVRASGFI
                     PPEAAETLCHDMIGKKYPALIEANLAGLRLGYENVKMAQGDRNLAPLPDAPAERYAWGY
                     ANAPIGGVNPRIGSTVSNDLTASREGYIPLFIPEKCINCGLCDTACPDMVFQFAPGIYR
                     EKNCMVNRGLDYYHCKGCLRCVEVCPTSALVPALEKDYPEKPHFLPNQHLLPDVIRYQT
                     VGANSWITSDSFTDEKRVDGGVV"
     CDS             11151..13628
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_112"
                     /sec_met_domain="PFOR_II (E-value: 6.5e-22, bitscore: 70.7,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 5.7e-55, bitscore: 179.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.2e-11, bitscore:
                     36.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKIMYDSGNELAAFAAKQINYHVMGYYPITPSTQIAENLDVM
                     GAEGLHDIALIAAEGEHSAAGICYGASAAGGRVFNATSANGLLYALEQFPVQSGTRMPM
                     VMNVACRTVSGPLCIKGDHSDVMYLLNTGWIILFADEPQKVYDFNLLGLKLAEAVRLPV
                     AVAFDGFFTSHQKRKCLVFENDDTVTRYIGEKLSCDNPKVSAFAGTGTCGAAGELPYAS
                     VLDLAHPVSIGSYMNEPDVINNRYQLHLAMEDARNKLPELFMEYAALSGRELSLCGAYR
                     HEDAKVLLFVLGSSYHTAMEAVDRLRQDGVAAGVITLYVLRPFPAKELRVLCHNASTIL
                     VADRQDSYGAGGGNMSLELKAALSSLPHPPRILSRIYGLGGKDFFVEDALALFKTALSP
                     DAPAFDYYGVTAGTDASDRAASSGTDSAGSDAVPTASHQAASINKDMTSSASGRADRTI
                     ADQTSGNSGKATPAMEISAMQPQYFKPVTKEESTPGLTTCIFDHAAGKMKVSGGSVKDT
                     TAMPMRVAPGHGACPGCGIPINVNLLLKGIEGNVVLLFQTGCGMVVTTGYPKTAFRVPF
                     LHNLFQNGAATLSGVVEAFHQRQKRGEYPDGEITFVMVSGDGGMDIGMGSALGTALRGH
                     KLIIFEYDNGGYMNTGYQLSYSTPLGAKSSTSHVGKTQYGKSFFHKDTPELMTATHIPY
                     VATVAESNPADFIRKAAKAAAYSREFGTAYIKALSACPLNWNDKPNLERSVIAAAVDCC
                     YFPLYEIERGITALNYDPASSNKKIPVAEWLGMMGRTRHLLKEEYRSVTEEIQKEIDRR
                     YDRLRARAKHPLL"
     CDS             complement(13819..14742)
                     /locus_tag="ctg7_113"
                     /transl_table=11
                     /translation="LFTMKKTIFLLVLVLIMGICTGCGKENTEIENSCMKEQTTSESSE
                     NDEIHLDDELNIDFTCDYSEDIKEDVDDVVAASTSLQEELTNMEKVTQKYTPLAEAAQT
                     QGEMNVAAQWLYTIWDTELNNLWSRLSSSADRQTKENLLAEQRNWIDMKEEVILLSIGS
                     REENGSMYPLLQNSYLEEITKNRAYVLARELAKIKGEDFAMPEVSAKYGTFVDNQGTGD
                     IYSSLLTRQNWEGKDEAVISIYRQGEMEGSFVDNGNGELNFTSEDGSVKGMIKIDGWNG
                     ASFKVTEIYGESPFSAGEEFEFPFVF"
     CDS             complement(14849..15388)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_114"
                     /sec_met_domain="Isochorismatase (E-value: 5.8e-29,
                     bitscore: 94.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLLVVDVQKGIVDERLYAFEKFVSNIRKLIETAREHGVEVCYIQ
                     HDDGPGTGFSIGDDAFEVYSEFQPMPAEKRFVKTVSSAFKKESGLLEYLTAKGEKDVMV
                     CGIMTDFCINATVEAGFEHGLHMIVPAYANSTLDNEYMTGEQSYHYYNEFLWPKRYADC
                     VSMDRALALLKKAIEV"
ORIGIN
        1 gcggagatcc ccatctcaat cgcgtgctca atcatgcttc ccatctggat cagttcattg
       61 ttcagttcta acagctgtct ctcaaatctg tttctcattg cttgctcctt tcatcaaccg
      121 aaacgtccgg taatgtaatc ctctgtccgc ttatcctgcg gcacggagaa caatttttcc
      181 gtatctccgc tctcaatgac ctcgccgagc aggaagaata cggtcttatc ggacacacgc
      241 actgcctgct gcatgttgtg cgtcaccata atgatcgtgt attttttctt cagttccacc
      301 gcgagatcct cgatcttcga ggttgagatc gggtcaagtg cagacgtcgg ctcatccatc
      361 agaatcactt ccggatcgac cgccagcgca cgtgcgatgc acagacgctg ctgctgtccg
      421 ccggacattc cgagcgcact ctttttcaac cggtctttca cctcatccca gatcgccgca
      481 tcgcgcaggg atttttccac gatctcatcc agttttgcct tggagcggat gccgtgcgtg
      541 cgcggtccgt atgcgatgtt gtcataaatg ctcatcggga acggattcgg cttctggaat
      601 accatgccga cacgcttgcg cagcaggttc acgtccatgc cgctgtagat gtcttccccg
      661 tcgagcagca cctgtcctgt gatcttacat ccctgtacca ggtcgttcat gcggtttaag
      721 cattttaaaa aggtggattt tccacagccg gacggaccga taaatgcggt aatttctttt
      781 tcgttaatgg acagatccac gtccttgagc gcgtggaaat cgccgtaata cagattcaga
      841 ttcgatatat taaacttttc tcccatgttt tcctcatttc cgcgcttcgc gctattcttt
      901 cactgcctca aaccgcttcg cgatcaagga tgagactcca tttatcagaa ggacaatgac
      961 aagcagcacc actgcagtcg catttgcttc atttttatgt aaaccttcat tagaaagcac
     1021 atacatatgg atggcgagcg tacgcccgga atccataagt cccgccacac cggtcacggt
     1081 acccgccgtg taaatgagcg ccgcggtctc tccgacgata cgtccgatcg agagaatgat
     1141 accggataga attcccggga ttgccgccgg aagcacaatc ttaaaaatcg tccgcagttt
     1201 tccggcgccc agcccgaagc ttccctctct gtaggaatcc ggcacacaca aaagcgcctc
     1261 ctccgtggtt ctcatgatcg tcggcagcac catgatggcg agcgtcgccg ctccggagag
     1321 catggaatag cgccagtgca gtgcaatgtt gaaaaacagc ataccgaaca gaccatagat
     1381 aatggaagga ataccggtca gcgtctccgc tgtcagacgg acaacctcca cgaatttatt
     1441 gccctttctg gcatattcga tcatgtagat tgccgccccc acaccaaatg gcacggaaaa
     1501 cagcagcgag accacaacca tctccaccgt gttgatgatg gcggggagca tggacacatt
     1561 gtccgaatta taatgtaatg caaacaggct cggctttagg tacggaatac cactgataag
     1621 gatgtagtcc acaagaaaaa gcagcgtcac caccgtgagc gcggctgcaa tcagaaccag
     1681 aagcagcagg atcaaagagc cgggatgtct ggtataggat ttcattttat cttttaatgt
     1741 tactttgttg attggattta tctgttccat cccctactcc tttccgcttc gcttgattgc
     1801 cgagaagcac agattgatga tcagaataaa cgcgaacagc accacgccag tagcgatcag
     1861 cgcctcccgg tgcagatccg tcgcatagcc catctccatg acaatgttcg tcgtcagtgt
     1921 gcggacgccc tgcagaatac tgttcgggac acgcggctgg ttacccacaa ccatcatgac
     1981 cgccatcgtc tccccgagtg cacgtccgac gccgaggatg accgccgcca gaataccgga
     2041 ttttgccgcc ggtaccacga cagtaaagac acttctctca tgcgttgccc cgagcgccag
     2101 cgctccttcg taataactct gctccactgc gcggatcgtc ggttcggacg ctccgatgat
     2161 ggtcggcagg atcatgattc ccagaagaat cgacgcacag agaatactct gtccgttgct
     2221 gttcttaaaa tgctcccgga tgaacggtac gagcacaacc agtccgaaaa atccgtatac
     2281 gatagacgga atgcccgcca gcaggttcac gaccggcttt aagagcttgt acagtccttc
     2341 cggacagaat cttgccataa aaatagatgt gagtacaccg accggcacac cgatgatcag
     2401 cgcgcctccg gtgacataga tacttcccag tatcatcggg aagataccga atttattgtt
     2461 tcccggcttc cacttggttc cggtcagaaa ttccgcaaat ccgattttct tcattgccgg
     2521 aattccgttt gcaaacagga atatgcagat cagcgccacc gccacgatgg agatgaccgc
     2581 agccaacaga aatacatatt ccatgatctt ctctcttttt ttcatcagaa cctccattta
     2641 caggtttttc ctaaataatg tgtatgttcc acgaaaggac cggaagaaca ttctgttccc
     2701 ccggtccgtc ctgctatgct atttctgctg tccgtcctag tttgctgcat cccaggttgt
     2761 tgtcccgcct gtgaaaatac cctttacggt gtcagaggag agatcctcta ccgggttctc
     2821 ctggtttacg atcactgcga taccgtccat ggcgatcttc gttgcgataa gtccttcctc
     2881 agtctcggaa tcctttaact cgcgggaagc cataccgatg tcgagtgtgc cgtctgctgc
     2941 tccggtcata cctgtggtag aatcacttgt ctgaagctcg atctccacat ttgcattgac
     3001 tgccttgtaa gcctcgatca gtttctccat taccggagat acggaagagg aaccgccgac
     3061 tacgactttg ccttctgctc cgttggactc gaatgctgct gcggaatcat ctccgatata
     3121 accgttgtcg gagattactt tctgcccgtc accgctcatg atgtagttga tgaaatcctg
     3181 tgcagcctcg ctgacctcgc cctttgttgc aatgttgaac ggtcttgcga tcttgtaggt
     3241 accgctcttg atgttctcta cggtagcctc tgccccgtca atttttactg cctttaccgt
     3301 gtcgtttaag gaaccaaggg atacataacc gattgcgtag gtgtcacctg ctaccgatgt
     3361 gagcataacg tccgtgctgt tggtgatgat cgcttcctct gtggtgttat ccactttctc
     3421 gccgctctca tctttttctt ccacaccgaa cagctcgatg aatgctcctc ttgtgccgga
     3481 accatcctca cgggaatata cggcgattgc tgatgtatga tcgaaatctg cattctctgc
     3541 cggtgcagct tcgcttgtgg tatctgctgc gtctgcggtg gatgctgcat ctgtggttgc
     3601 tgctgcatct gtggtggtgt ctgctgtatc actgctgccg catcctgcga acatgcccgc
     3661 tgccataaca cctgtcaata acatacacat tactttcttc ttcattttga atcctccatt
     3721 caattttacg gaatttcttc tccgtttttt cttttacctc gtttcttaga acatggttta
     3781 ctttacggga ggaatgtaaa atgcagaaga gcacttatgt aaaacctgtg taaaaatcct
     3841 gtcacatcat ttcgatctgc tggcgcagct ctaacatctt attgtccacc tttgcgatca
     3901 catccgagta gccgcgcgtc tcgcgctcca cattggcgat ctgtccggca tccttcttat
     3961 aacacatctg tgtgtccagc tccgcccagt aatccattgc aaacgagcgg atctggatct
     4021 ctacccggat ctccgtgacc gtgtcgttgt acgtcaccgg aacgcccgca atcacatgaa
     4081 tactctgata gccgctcttc ttgggatttt tcacataatc cttttccttg ataatatgaa
     4141 aatccttctg cttcttgatg gcatccgcaa tccggtagat gtcgtcacag aaaaagcaca
     4201 cgacccggat gccggcgatg tcattgagag tctgcaccgc ctcctcaaaa gagacttccc
     4261 gccctttctt tttgagtttt ttggtgacgc tgtctggcgt cttgatgcgg caggacatat
     4321 tgcgaatgac ctggcggtgg cattgttccg tcaggtcagc attgatcagt cttaatcgtg
     4381 cctgtacgag atccatggca gcggcatagg atagctgcac catcggctgt aacagtttct
     4441 cactcaacag gtcctcattc ggcaattttt gttctccgtt ttgtttttcc tttatttcta
     4501 ttcgcttctt tttcttttta gaatcattct ttggcaaaac ccgctgcgcc tcccatcgca
     4561 ccgctctgtg acgtctcccc ctccatgcac cggcgctgca tctgaaagca gataaatccc
     4621 acaacaaaca tagcggcgat cgctgccaca ccggctcttg atgtatcaaa cagctgcgtg
     4681 gtgattccca tcagcatcgt tcccataaag gaagctcctt ttccaaaaat atcgaagatg
     4741 ccgaaatact ccgtcgactt ttccttcggg atgatcttgg catagtagga acgggagagc
     4801 gcctggatgg ctccctgaaa tacaccgaca aacgttgcca tcatccagaa tttccacgcc
     4861 gcatccagcc agagtgcata gaccgcaacc acaaagtagg caccgatgca gaccgaaatg
     4921 agttttgaag atgcaaagcg ctgggtcagt tttccgaaca gaatcgcgca cgggaatgcg
     4981 acgacctgcg tgagcagcaa tgccatcaga aggctggtgt cgctgattcc gacgtctttt
     5041 ccgtaggaag tcgccatctc gatgatggta tacacgccat caatatagaa gaaaaacgct
     5101 gccagaaacc acagcacctt tttgtcatcc cggatctccg caaagacttt gccgagtctg
     5161 gaaaaaatcc cgcgcacatc ggtgccgccc gcttccacat agtatttctg ctgatagttc
     5221 cgcagcagcg ggagtgtcac aaccacccac catgccgcgt tgataaaaaa tgcaatcatc
     5281 atcgcaaccg tgccggaaat gccgatcgca tccgcgccga ggatcagacc gaggctcgcc
     5341 acaaacggca cgcagcttcc gatatatccc cacgcgtatc cctgggagga cacctcgtcc
     5401 atccgctcat ccgtcgtgac atccacaagc atggaatcat agaaaatgag gcttccggaa
     5461 aatccgactt ttgcaatcac aaaaatggca aggaacagaa tccatgtccg cggaatcgca
     5521 agcgccgcac agccgagcac tcccatcatc atgaaaaatg taaacagcgg cttcttgcgg
     5581 ttcttattgt cggcgaccgc accgagcacc ggtcctaaaa ccgccacgat cagcgttgag
     5641 atcgagatgg cgtaacttaa atatgcggta gaatccgagg cgctgatgcc gtttgctgac
     5701 gccatgtttt tgtagtagat cggtataatc gtcgacacca gaagtgtgaa cgccgaattt
     5761 ccgacatcat acagtaccca gaatttttcg agtctactca tttttgtttt cataatcttt
     5821 tacctcttct tccttaataa agcggaatat ttcatcatag tatttcacac gcgtccgctc
     5881 atccgcatta aaaatctcat gtctggaatc cggcatagag aaaagctttg tccgctccgt
     5941 ctcctccgca aaccgcccga tcgcaccgtt atccaccatg tgatcgcacc ctgctgcaaa
     6001 gagcagcacc ggcaccttga tctttgccag attctcccgc cgcatcagtt cgcggctggc
     6061 gcgaaaccct gcgcggaccc aggcataact tccgccgtag gttcggtaat gttcctctaa
     6121 gagccgcttt tgaaacatat agtcataacg ctctcttgag agacagctgc tcccctcaaa
     6181 ttgcggtgcc tctgaaaatc cctgctgtcc cgccagtgtg gcaaagcatt ttccttttcc
     6241 ggccagacag cagaactccg ccagcagccg tgcagcaaac cgcggatatt ttccggtctg
     6301 catggcgcac atcggtgcgg agagaactgc cgcctcaaac agctgtggat aacgttccag
     6361 tgcaaggatc gcaatggcgc ctcccatcga atgtgcaaac acgatccggt gttcctccct
     6421 ggggcttacg accgtctcca caaaccgcgc aaaatccgtg acatatctgt catagctctg
     6481 cacatgcacc agctccgggt catccacctc gcgcccggaa tagccgtgtc cccgatgctc
     6541 cggcacatag accgagtatc cctcctgcag aaaacggtat gcgacttcgt tatatttttc
     6601 cgcgaattcg caaaatccgt gggaaatcac aacacatttc cccgcatccg gcagcgaata
     6661 tcgccggtaa gcgatcgaca tgccatcttc catcttaaga tagcccttct cgccgtgctc
     6721 tttcagataa ggttctaccg tctccgccat ccaggcggca taacctgcat cctccgctcc
     6781 cgcgcgtttt ttattttccg gcgtcatgcc tgattcccct gcttctttat cacgcggaca
     6841 agctccggcg tcagttttcc atccacgtat tctgcggcaa tccgtctgcc cgtatccggg
     6901 taattcgtga tcatagcgtc cacctgcatc tcgcacacca tgcgcatgta ctgctcctcg
     6961 ttgaccgtcc agacatgcac acgctttccg tgctttttac agtcttccat gtaattcgag
     7021 tactgcagat tgtagagtgc cgggtgcatg gcgtccgcgc ccacgacgag cgcgccgtag
     7081 ctgaccggat tgacaatgcc gtcgcagtag agcatgccgg tcttcgcctg cggattcagc
     7141 tccttgatac gctgcaccgt gtagtggtta aacgacgagt accacacgcg ctcctccaga
     7201 cccatgcggg cggtcagatc aagcacgcgc tcttcgatct ccggataaaa gaccacgccg
     7261 gtcttcaatt ccacattgat cgtaagtccc gtcggcttta acagctcata gacttcctcg
     7321 agcgtcggga tcatcgcccg ctcgtaccct tccttatgcg tccggttgta attaaatctg
     7381 gaaattctcg cgtatgtaaa atctttgacc cagccgctgc cgtcgctggt acggtcaacc
     7441 gtctcgtcgt ggatgacgac cagttctcca tcctttgtga gctgcacatc cagctccacg
     7501 ccgtccgcgc ccatctcaac cgctttccgg aatgcctcca gtgtattttc aggcgcgtag
     7561 ccgcttgcgc cgcggtgcgc ccataccaat gtctgttttt ccatgtatac aaaaacctcc
     7621 gatatgatag cttcttattt cttctatcat atcggaggtt tgtaaaattg ttcgggtgta
     7681 ttgcgtaaaa tttaaaatgg ctatgtaaaa tgtctgtaag atatcatgcg ttttttgcct
     7741 gccttacatt gtaggccgtc gccgaaccga ccaccagcag ggcaccgata acagcggttg
     7801 caccgattgt ctccccataa aaaacagcca ccagaatcgg atttaagatc ggctcgatcg
     7861 tcgaggtcag cgacgccgtg acaggagaga ctgcgtccag tccccgcgac aggaacacat
     7921 aggacagacc gaactgcacc acgccgagca gcagcacgaa gaaccagata tgcagtgaca
     7981 tctcgctctc ctgcccgtaa aacgggattc cgatcgccgc gctcaacgcg caggacacca
     8041 gaagcgacga ttcaaagtcc gcgccgcgga atttcttctg catcatcaca agcgcatagg
     8101 caagtcctga gagaatcgca agcagattcc ccgccatggc tccggcatcc agcgacgtat
     8161 aaaagaagca gagaatccct gcaaagactc ccgcgcaggc aaacaccgaa tcccgccccg
     8221 gctttttgtg aaagatcagc cacatcagga gaatgacaaa caccggctct gtgaactgca
     8281 gcacgatcgc attggcagcc gtcgtgagct tggtcgccgc cacaaaggca aacgccatca
     8341 ccgtattgca caccgcaccg aagagcaccg tcttattcca cacaaacttc tggcggcgca
     8401 gaagcatgta acatcccaca accagcaccg agaaaatact gcgcgctccc tggatcgtca
     8461 ccgacgacca cggaatcgac ttgattaaaa cgcctccggt gctgaaacag actgccgata
     8521 acagtacgca gaccgttccc cgcagacttt ccgcattcat ttttttatca ctcatatcca
     8581 ttcctcccat ccgggtttct gtcgtattct ccatccgctc ttctgtcgta ttctccatcc
     8641 gctcttctgc cggattctcc catctgtgct actgccactt cctatgagat aaaaacatag
     8701 accagcacga gtactgccag aaacagtacg tttgcgatcg taaaccacag gagataccgc
     8761 cccttggtct tattataatt gtgcgcgtag atcttataag agatcaggct cgccatcgaa
     8821 gcgatgagcg ttcccagtcc gcccagattc acgccgatcg taagattttt cagattgtgc
     8881 gtaaaatctg ccagaagcag ggtcgcggga acattgctga tgatctggct cgcaccgatg
     8941 ccgaccgcca gttccctgcc cgccacaaga ctttgcagga cagaccgtac cgcctcgata
     9001 ttccccatat tgccgatgaa gatgaagaaa ctgataaacg taaacagcag acagtaatcc
     9061 acctgcaaaa acaccgcgcg atccgtaaaa atgagtacaa tgagcaccac ggcgagcatt
     9121 agctcccacg gaagcacccg cgctaccgaa agcaggctta gcacaaagag cgccagataa
     9181 atcccgtttt tcttcctgcc ggctgctccg gacgtctgca aaagtgcccc cgtctccagc
     9241 gagatccggc gcttgcccgc actgagcacg aacacgacaa gcagcagaag cacacctgac
     9301 acgagcgtat acggcgccat ccatccgata aattcaccca gcccggcacc ggagacgctg
     9361 taaagataca gattctgcgg attcccgacc ggcgtcagca tgctccccag attcgctgca
     9421 agcgtctgca gcacaaacgt tgtcacaatc agccgctcct ggtggcattt ctgcaggatc
     9481 gtgcacgcaa acggcacaaa cgtcaaaagt gcgacgtcgt ttgtgataaa catactggaa
     9541 aaaaagcaca aaaaaacaag caccagcatc agctgcgcgg tatttttggt ctttgccaga
     9601 agccggctgc cgatagcatc gaacagtccg ttgctctgaa atcctgccac aatcagcatc
     9661 agcgacagca aaatgccgag cacgcgccag tcaatgtagc ccacgtactg cggacccggg
     9721 tgcacccaga atgccgatgc cacagcgaag gctgtggcga tcgtgagtac cgtttctttt
     9781 tttataaaat ctgtgatctt ctgcaacatg ttgtccatca tcttttctgt ttcattgtaa
     9841 aaattccttt cctattttac ttctcttttt tgcacttgca taggattttt ttctgaaaat
     9901 gcggcatact accacaagat agcctgttat cgctgtatgc gcacagccga tgcctgtcat
     9961 tttcccatgc acagctgccc gcgcaggaat ggagatttac gtgaaaaata cattatcctt
    10021 acctgtcaca aatgaaaacg gctcctatga gatccgcctg gagagcatcg gcgggctggg
    10081 cgccaatctc tgcggaaaaa tgctcggaga gctcggcgca ctgtcgcttt cgctcaattc
    10141 cttaagcttt tccagctacg gctccgaaaa gcgcggttca ccggtcaagg cgtatgtccg
    10201 ctggtgcgca gacgaccgcc cgctgcgcgt caacagcccc gtgacccggc cacatctgct
    10261 cggcatcttt cacgaaggac tgatcggcac ctacccggtc ttggacggcg tcaccgtaga
    10321 caccaaaatc gtattaaata cccccttgtc cgctgacgag gcggcagata aataccatat
    10381 ttccatcgga gaactctatt gtctggatgc gctcgcactt gcgatggaaa gtcattcccg
    10441 catcaacatg gtcatgctcg gtgctctggt gcgcgccagc ggatttatcc cgccggaagc
    10501 tgccgagacg ctctgccacg atatgatcgg gaaaaaatat cccgcactca tcgaagccaa
    10561 tctcgcgggt ctgcgcctgg gatatgaaaa tgtcaaaatg gctcagggtg accgcaacct
    10621 cgcccctctg ccggacgccc cggcggaacg gtatgcttgg ggctatgcca acgctccgat
    10681 cggcggcgtc aatccgcgga tcggaagcac cgtctccaac gatctgaccg cctcgcgcga
    10741 agggtacatt ccccttttta ttccggaaaa atgtatcaac tgcggactgt gtgacacggc
    10801 atgcccggat atggtcttcc agtttgctcc cggcatctac cgcgaaaaaa actgcatggt
    10861 caaccggggg cttgactact atcactgcaa gggctgcctg cgctgtgtgg aagtctgccc
    10921 caccagtgca ctcgtgccgg cactcgaaaa agattacccg gaaaaaccgc attttcttcc
    10981 gaatcagcat ctgctgcccg acgtcatccg ctatcagacc gtcggtgcga attcctggat
    11041 cacaagcgat tcttttaccg acgaaaagcg ggttgacgga ggcgtcgtat aaatgcaggc
    11101 agcaccagtg aatcgtaccg gcgcatagcg tctgcagaat ggagaatgat atggaaaaac
    11161 aaaaaattat gtatgacagc ggcaatgagc ttgccgcatt tgccgcaaag cagatcaact
    11221 atcacgtcat ggggtattat ccgatcacgc cctctacaca gattgcggaa aatctggatg
    11281 tcatgggcgc ggaggggctt cacgacattg ccctgatcgc cgccgaggga gaacacagcg
    11341 ccgccggcat ctgctacggc gcctcagccg ctggaggccg tgtatttaat gccaccagcg
    11401 ccaacgggct tttgtacgcc ttagaacagt ttccggtgca gtccggcaca cgcatgccga
    11461 tggtcatgaa tgttgcatgc cgcacggttt ccggtccttt gtgcatcaaa ggcgatcaca
    11521 gcgacgtcat gtatctgctc aacacaggct ggatcattct ttttgccgat gaaccgcaga
    11581 aagtctatga ttttaacctg ctcggtctaa agcttgccga agctgtccgt ctcccggtcg
    11641 cagtcgcgtt cgacggcttt tttacgagcc atcagaagcg caagtgcctt gtatttgaga
    11701 atgatgacac cgtcacccgc tatatcgggg aaaagctttc ctgtgacaat ccgaaggtct
    11761 ccgcatttgc cggcaccggc acctgcggcg ctgccggaga gcttccctac gccagcgtct
    11821 tagatctcgc gcatccggtt tccatcggtt cctatatgaa cgagccggat gtcatcaata
    11881 accgctatca gctccatctc gccatggaag atgcgagaaa caagctgcca gagctgttta
    11941 tggaatatgc cgccctctcc ggcagggaac tttccctctg cggtgcctac cggcacgagg
    12001 atgccaaggt tctgcttttc gtgctcggtt cctcctacca caccgccatg gaagccgtcg
    12061 accggctgcg gcaggacggc gtagcggctg gcgtgatcac cctatacgtt ctgcgcccgt
    12121 tccccgccaa ggaactccgc gtcctctgcc acaatgcttc cacgattctt gttgcagacc
    12181 ggcaggacag ctacggagcc ggcggcggca acatgtcgct tgaattaaag gccgctctct
    12241 cttccctgcc gcacccgccg cgcatcttaa gccggatcta cggtctcggc ggtaaggact
    12301 ttttcgtgga ggacgccctc gctctcttta aaacggcact ctcgccggac gctccggcgt
    12361 tcgattacta cggcgttact gccggcacag acgcttcgga tcgggctgct tcctccggga
    12421 cagattccgc cgggtcggac gcggtgccga cagcttcaca ccaggcagcc tctatcaaca
    12481 aagatatgac ttcaagtgcc tccggcaggg ctgaccgcac aatagcggat cagacttcgg
    12541 gcaattccgg caaagccacc ccagcgatgg agatttctgc gatgcagccg cagtatttta
    12601 agcctgtcac aaaggaagaa tccacaccgg gtctcaccac ctgcatcttc gatcacgcag
    12661 ccgggaaaat gaaggtctcc ggcggctccg taaaagatac gaccgccatg ccgatgcgcg
    12721 tcgcaccagg acacggcgcc tgcccgggct gcggcattcc gatcaatgtg aacctcctgt
    12781 taaaaggcat cgaaggcaac gtcgtcctgc tgtttcagac cggctgcggc atggtagtca
    12841 caaccggcta ccccaaaacc gcgttccgcg ttccatttct gcacaatctg tttcagaacg
    12901 gtgcggcgac cctaagcggc gttgtggaag cgtttcacca gcgccagaaa cgcggggaat
    12961 acccggacgg cgagattacc tttgtgatgg tgagcggtga cggcggcatg gatatcggta
    13021 tgggttcggc actcggcacc gccctgcgcg gtcataagct gatcattttc gagtacgata
    13081 acggcggcta catgaatacc ggctaccagc tctcctactc cacgccgctc ggcgcaaaaa
    13141 gctctacttc ccatgtcgga aagacgcagt acggcaagag tttcttccat aaggacacgc
    13201 cggagctgat gaccgcgacc cacattccct atgtcgcaac agtcgcagaa tcgaatccgg
    13261 ccgattttat ccggaaagcg gcaaaggcag ccgcctattc cagggagttt ggcactgcct
    13321 atatcaaagc gctgtctgcc tgtccgttaa actggaacga caagccgaat ctggagcgga
    13381 gcgtcattgc cgccgctgtg gactgctgct attttccgct ctacgaaatc gaacgtggca
    13441 tcacagcgct gaattatgat cctgcttcga gcaataagaa aatccctgtc gcggaatggc
    13501 tgggcatgat gggacgcacc aggcatctgc tgaaggagga gtaccgctcc gtgaccgagg
    13561 agatccaaaa ggagatcgac cggcgctacg accggcttag agcgcgcgcc aagcatccgc
    13621 ttctgtagac gcgcagagag aatgaaccgg cgggatgctg tgtccggaag ctcatagcca
    13681 gaccggtaat tgaaagggcg gcaggaattt cttcctgccg ccctttccac tccattccgt
    13741 gtctcttgcc acgctttgac actccgcgga cacacccgcg gagtgctcaa agcctgaaaa
    13801 gacacagagc atcacaaatc aaaagacaaa aggaaattca aactcttctc ctgcagaaaa
    13861 cggagattcc ccgtatattt ccgtaacttt aaaactcgcg ccattccatc cgtcaatttt
    13921 gatcattcct tttacacttc cgtcttctga tgtaaagttc agttctccat ttccgttatc
    13981 cacaaagctt ccttccattt ctccctgcct gtaaatagag atcactgctt catcttttcc
    14041 ttcccaattc tgtctggtga gcagagaact atatatgtca ccggttccct gattatctac
    14101 aaaggttccg tactttgcgg aaacttccgg catagcaaag tcttcccctt ttatcttcgc
    14161 cagctctctt gcaagaacat acgccctgtt ttttgtaatt tcctccagat aagaattctg
    14221 aagaagcgga tacatactgc cgttttcttc tctggaacct atgcttaata aaatcacttc
    14281 ttctttcata tctatccagt ttctctgctc tgccagaaga ttctccttcg tctgccggtc
    14341 cgccgaacta ctcaatctgc tccaaagatt attcagttcc gtatcccata tcgtataaag
    14401 ccattgcgcg gctacattca tttcgccctg cgtttgtgcc gcctcagcta atggcgtata
    14461 cttttgtgtg accttctcca tattcgtcaa ctcttcctgc agagatgtgg aagccgctac
    14521 tacatcgtct acatcttcct taatatcctc agaataatcg caggtaaaat ctatattcag
    14581 ttcatcatcc aaatgaatct catcgttttc actgctttcg gatgtagttt gttctttcat
    14641 gcaggaattt tcgatttctg tattctcttt accacatccg gtacaaattc ccatgattag
    14701 caccagtacc agcagaaaga ttgttttttt catagtaaac aaaactaaat ctccatcaca
    14761 gatggccttg ccggggcaat tatttatgcc ggacactgta atagcgtgcc gatcattaaa
    14821 gtttatcaac atatatctat atctatatct atacctctat cgcttttttg agtaatgcca
    14881 atgccctatc catggatacg caatccgcat agcgttttgg ccagagaaac tcattatagt
    14941 aatggtagct ctgctcccca gtcatgtact cattgtccag cgtggaattt gcataggcag
    15001 gaacgatcat gtgcagtcca tgctcaaaac cggcctctac tgtagcattg atgcagaagt
    15061 cggtcataat gccacagacc atcacgtctt tttcgccctt tgctgtcagg tactccagca
    15121 gaccactctc tttcttgaat gcactgctta cggtcttgac gaatcgtttt tcagcgggca
    15181 tcggttgaaa ctcagaatag acctcaaacg catcgtcccc gatggaaaac ccagtacccg
    15241 gcccatcatc gtgttgaata tagcaaactt ctaccccatg ttctcgagcg gtctcaatca
    15301 gcttcctgat attactgaca aacttctcga acgcatataa gcgttcatcc acgatgcctt
    15361 tctgtacatc gacaaccaat aaaaccatgt gcgatctctc cttttttctt tcgctatatc
    15421 ccaccacaaa ttacaagccg cagatcacta cattgtccgc cgcgcctttc cctgtttcta
    15481 atcagtcaaa cttgaatttg ttactctttt gtatcgtaaa taattttgcc cgtaaagtaa
    15541 attgaaatgt ccatttgaac taaatcttct gtttctaaga tagataaata accagaatag
    15601 cattaagcat agccatgtag actatatcac ttccaaattc aaataatcgc gtgcttttat
    15661 agctcgcctc tcaaacgtgc ttctatatca gatgccgtgt at
//
