LOCUS       c00103_gnlPro..        12940 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BIOKPEKA_103.
ACCESSION   c00103_gnlPro..
VERSION     c00103_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 20:26:13
            Original ID  :: gnl|Prokka|BIOKPEKA_103
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12940
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..153)
                     /locus_tag="ctg103_1"
                     /transl_table=11
                     /translation="MSFSELYLIYYPKLVRFAKEFVMSEEDAENITQDVFTDLWEKRES
                     MNHIEN"
     protocluster    1..12940
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2706:12907]"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2707..12907
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
     cand_cluster    1..12940
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /kind="single"
                     /product="NADH_dehydrogenase_I"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12940
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NADH_dehydrogenase_I"
                     /region_number="1"
                     /rules="(Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and
                     Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2
                     and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7,
                     Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3,
                     NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(346..1950)
                     /locus_tag="ctg103_2"
                     /transl_table=11
                     /translation="MKRTLWFIFFLLNSLFYLYADSENDSLLKVLDKVISERLIYTQKK
                     EATIKELKKKKVGLNSLEDIYNLNKEIIHQYETFVCDSAEQYIHENIDIAKTIGNKEYL
                     LEEQLRLAFVYSLSGLFIQANDIFKSIKCADLPDHLKALYCWNRIRYYENLIKYTDDVR
                     FSNEYISEKEAYRDTVMSILFDQSDEYRKEKAVKLQDKGSTKEALLILTEIYDKQEPAS
                     HGYAMMAMGLARAYRLIGNYALEEKFLMLAAMTDTKLAVKENEALLTLAVNLYHKGDID
                     RAYNYIKVALDDAIFYNSRFKNTVIARIHPIIENTYLIRLEKQKQNLRFYIFLTSLFVV
                     ALAITLYFTYKQTKIVSRAKRHLKAMNEELVGLNKNLDEANLIKEKYVGYFMNQCAVYI
                     NKLDEYRKNVNRKIKTGQIDDLYKSSSRPFEKELEELYHNFDKAFLNLYPNFVEKFNSL
                     LKPEERYKLEKDQLNTELRIFALIRLGITDVGQIAVFLHYSVQTIYNYKSKVKRMSTLD
                     SNIFEEEVKKLGSLSQK"
     CDS             2211..2588
                     /locus_tag="ctg103_3"
                     /transl_table=11
                     /translation="MKQSLKFGLLLVLALLIHCATNGAMEDMCKVSSPTYRQEKCYVSQ
                     DRPIQDALERLYNLYTTQTCDMSHTDVAHVPTDKSMFLLIAYFCDHYKHQSPPYPVSSH
                     SPTYYYDPISYYIYGLRKIVI"
     CDS             2707..3057
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_4"
                     /sec_met_domain="Oxidored_q4 (E-value: 2.7e-38, bitscore:
                     120.0, seeds: 391, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFTFLVVVLLTALAFVGVVIALSRAISPRSYNLQKFEAYECGIP
                     TRGKSWMQFRVGYYLFAILFLMFDVETAFLFPWAVVMRDMGPQGLISVLFFFIILVLGL
                     AYAWRKGALEWK"
     CDS             3048..3650
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q6"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_5"
                     /sec_met_domain="Oxidored_q6 (E-value: 1.1e-26, bitscore:
                     83.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITKKPKIKSIPYDEFIDNESLEKLVKELNAGGANVALGVLDDF
                     INWGRSNSLWPLTFATSCCGIEFMALGAARYDMARFGFEVARASPRQADMIMVCGTITN
                     KMAPVLKRLYDQMPDPKYVVAVGGCAVSGGPFKKSYHVVNGVDKILPVDVYIPGCPPRP
                     EAFYYGMMQLQRKVKIEKFFGGVNRKEKKPDYLRNEE"
     CDS             3733..5325
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_30kDa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_49kDa"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_6"
                     /sec_met_domain="Complex1_30kDa (E-value: 1.1e-36,
                     bitscore: 115.9, seeds: 586, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_49kDa (E-value: 8.7e-66,
                     bitscore: 211.5, seeds: 265, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQEIQFIAPAALHDEMLRLRNEKQMDFLESLTGMDWGVADEKDAP
                     EKLRGLGVVYHLESTITGERIALKTATTNRELPEIPSVSDIWKIADFYEREVFDFYGIT
                     FVGHPDMRRLYLRNDWIGYPMRKDNDPEKDNPLCMTNEETFDTTQEIELNPDGTIKNKE
                     TKLFGEEEYVVNIGPQHPATHGVMRFRVSLEGEIIRKIDANCGYIHRGIEKMNESLTYP
                     QTLALTDRLDYLGAHQNRHALCMCIEKAMGIEVSERVQYIRTIMDELQRIDSHLLFYSC
                     LAMDLGALTAFFYGFRDREKILDIFEETCGGRLIMNYNTIGGVQADLHPNFVKRVKEFI
                     PYMRGIIHEYHDIFTGNIIAQSRMKGVGVLSREDAISFGCTGGTGRASGWACDVRKRMP
                     YGVYDKVDFKEIVYTEGDCFARYLVRMDEIMESLNIIEQLIDNIPEGPYQEKMKPIIRV
                     PEGSYYAAVEGSRGEFGVFLESQGDKTPYRLHYRATGLPLVAAIDTICRGTKIADLIAI
                     GGTIDYVVPDIDR"
     CDS             5346..6422
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: NADHdh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_7"
                     /sec_met_domain="NADHdh (E-value: 4e-123, bitscore: 400.2,
                     seeds: 435, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDFSIVTNWIHELLLSIMPEGLAIFIECVAVGVCLVALYAILAI
                     ILIYMERKVCGFFQCRLGPNRVGKWGSIQVVCDVLKMLTKEIFMPKGADHFLYNLAPFM
                     VIIASFLTFACIPFNKGAAILDFNVGVFFLLAASSIGVVGILLAGWGSNNKFSLIGAMR
                     SGAQIISYELSVGMSIMTMVVLTGTMQFSEIVEGQANGWFIFKGHIPAVIAFIIYLIAG
                     NAECNRGPFDLPEAESELTAGYHTEYSGMGFGFFYLAEYLNLFIVASVAATIFLGGWMP
                     LHIVGLDGFNTVMDYIPGFIWFFAKAFFVVFLLMWIKWTFPRLRIDQILNLEWKYLVPI
                     SMVNLLLMACCVAFGFHF"
     CDS             6435..6923
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_8"
                     /sec_met_domain="Fer4_7 (E-value: 3.4e-13, bitscore: 39.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.8e-06, bitscore: 15.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYKDKKYTYLGGLVHGISTLTTGMKTSIKVYFRKKVTEQYPENR
                     KELKMFDRFRGTLNMPHNENNEHRCVACGLCQMACPNDTIKVTSETVETEDGKKKKILA
                     TYEYDLGACMFCQLCVNACPHDAITFDQNFEHAVFDRTKLVLKLNHDGSKVIEKKKEV"
     CDS             6926..7438
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_9"
                     /sec_met_domain="Oxidored_q3 (E-value: 4.5e-38, bitscore:
                     120.0, seeds: 708, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSTLETVVFYFLAAFIIAMSIMTVTTQRIVRSATYLLFVLFGTA
                     GIYFLLGYTFLGSVQIMVYAGGIVVLYVFSILLTSGEGDRAEKAKRSKVLAGLFTMIAG
                     LAIILFITLKHDFMQTANLAPQEISIHAIGNALLSSDKYGYVLPFEAVSILLLACIIGG
                     IMIARKR"
     CDS             7476..7784
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_10"
                     /sec_met_domain="Oxidored_q2 (E-value: 2.9e-22, bitscore:
                     68.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHMEYYLVVSTIMMFAGIYGFFTRRNTLAILISVELMLNATDIN
                     FAVFNRFLFPGGMEGYFFALFSIAISAAETAIAIAIMINIYRNLRSIQVRNLDELKW"
     CDS             7976..9907
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_11"
                     /sec_met_domain="Proton_antipo_N (E-value: 2.1e-25,
                     bitscore: 78.5, seeds: 433, tool: rule-based-clusters)"
                     /sec_met_domain="Proton_antipo_M (E-value: 5.9e-87,
                     bitscore: 281.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTILILLLPFFSFLILGIGGKWMSHRTAGTIGTLILGAVAVLS
                     YVTAIQYFSAPRLEDGTFATLMPYNFTWLPFTETLHFDLGILLDPISVMMLIVISTVSL
                     MVHIYSFGYMKGEVGFQRYYAFLSLFTMSMLGLGVATNIFQMYLCWELVGVSSYLLIGF
                     YYTKPAAIAASKKAFIVTRFADLGFLIGILIYGYYGGTFGFTPDTISLISGGASMLPLA
                     LGLMFVGGAGKSAMFPLHIWLPDAMEGPTPVSALIHAATMVVAGVYLVARMFPLFITYA
                     PNTLHMVAWVGAFTAFYAASVACVQSDIKRVLAFSTISQIGFMMVALGVCTSMNPHEGG
                     LGYMASMFHLFTHAMFKALLFLGAGSIIHAVHSNEMSAMGGLRKYMPITHWTFLIACLA
                     IAGIPPFSGFFSKDEILAACFQYSPVMGWVMTVIAAMTAFYMFRLYYGIFWGSEPPRAG
                     SHSEHNTPHGNLEAAPCRPHESPLAMTFPLMFLAVVTCGAGFIPFGHFISSNGESYSIH
                     LDPSVTITSVVIAIISIAIATWMYKNAKQPVADSLAKRFKGLHKAAYNRFYIDDIYQFI
                     THKIIFRCISTPIAWFDRHVVDGFFDFLAWATNTTSDEIRGLQSGQVQQYAYVFLCGAL
                     ALILLLIL"
     CDS             9946..11430
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_12"
                     /sec_met_domain="Proton_antipo_M (E-value: 2e-68, bitscore:
                     220.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSIFVLIPLLMLAGLWAARGIKAIRGVMVTGASALLIASVVL
                     TFLYLGERSAGNTAEMLFRADTLWYAPLHISYSVGVDGISVAMLLLSAVIVFTGTFASW
                     RLQPLTKEYFLWFTLLSMGVFGFFISVDLFTMFMFYEIALIPMYLLIGVWGSGRKEYAA
                     MKLTLMLMGGSAFLLIGILGIYFGSGATTMNLLEIAQLHNIPFAQQCIWFPLTFLGFGV
                     LGALFPFHTWSPDGHASAPTAVSMLHAGVLMKLGGYGCFRIAMYLMPEAANELSWIFLI
                     LTGISVVYGAFSACVQTDLKYINAYSSVSHCGLVLFAILMLNQTAATGAILQMLSHGLM
                     TALFFALIGMIYGRTHTRDVRELAGLMKIMPFLSVCYVIAGLANLGLPGLSGFIAEMTI
                     FVGSFQNNDVFHRTLTIIACSSIVITAVYILRLVGKILYGTCTNKHHLELTDATWDERV
                     AVICLIVCVAGLGMAPFWVSHMIGESVLPVVSQLIP"
     CDS             11468..12907
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_13"
                     /sec_met_domain="Proton_antipo_M (E-value: 1.7e-73,
                     bitscore: 237.1, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYSQFLNMREELSLIAVLLLLFLADLFMSPDAHKNSGKARLNTM
                     LPVILMAIHTAINLIPGTAADAFGGMYHYVPMHTVVKSILNVGTLIVFLMAHEWMKRED
                     TSFKQGEFYVLTLSTLFGMYLMISAGHFLMFFIGLETASIPMAALIAFDKYRHNSAEAG
                     AKYILTALFSSALLLFGLSMIYGSAGTLYFDDLPAHIDGNPLQIMAFIFFFTGMAFKLS
                     LVPFHLWTADVYEGAPSAVTAYLSVISKGSAAFVLLAVLIKVFAPMINDWQEVLYWVTI
                     ASITIANIFAVRQQNLKRLMAFSSISQAGYIMLGVIGGTAQGMTALVYYVLVYAAANLG
                     VFAVITIVALRSQKFTLEDYAGLYKTNPKIALLMTLSLFSLAGIPPFAGFFSKFFIFMA
                     AFDAGFHLLVFIALVNTVISLYYYLLIVKAMYITPSDNPIPTFRSDRCTKWGLALCTLG
                     IIGLGIASIVYQSIDKLSFGI"
ORIGIN
        1 attctcaata tgattcattg actctctctt ttcccataag tctgtaaaca catcttgtgt
       61 tatgttctca gcatcctctt ccgacatcac aaattctttt gcaaaccgaa ctagcttggg
      121 ataataaata agatacaatt ctgaaaaact catagttgtg tgtttcttta gattagtatt
      181 cagttatcaa aaatcttgtg atgcaaatat agagatgaaa aaagcctact tcttagtgga
      241 agtaggcggg aaagtaaacg ttttataaat caattattgt atatacattt aataatcaac
      301 aatttacaat aagatcattt tttagttttg gtaaaccgga tagaatcatt tttgagacaa
      361 agaaccaagc ttttttacct cctcctcaaa gatattacta tcaagagtgg acattctctt
      421 cactttactc ttataattat agattgtctg cacagaataa tgcaaaaata cagcaatctg
      481 tccaacatcg gtaattccta atcgtatcaa tgcaaatatg cgtaattctg tattcagttg
      541 gtccttttcc agtttataac gctcctccgg tttcaacaaa gaattgaact tttccacaaa
      601 gttaggatac aaattaagga acgctttatc aaagttatga taaagttctt caagttcctt
      661 ttcaaaaggt cgggaggatg acttatataa atcatcaatc tgtccggtct tgattttcct
      721 gttcacattc ttcctgtact catcgagttt attaatataa acggcacatt gattcataaa
      781 ataccccaca tatttttcct taatcagatt agcttcgtcg agattcttat tcagcccgac
      841 cagttcctca ttcatagctt taagatgccg tttagctcgg gatacaattt ttgtttgttt
      901 atatgtaaaa tacagggtga tagcaagagc taccacaaac aagctagtca gaaatatata
      961 gaaacggagg ttctgctttt gtttttccaa ccggatcaag tatgtatttt caataatcgg
     1021 atggatgcgg gcaattaccg tattcttaaa acgggaatta taaaagatgg catcatccaa
     1081 cgctacttta atataattat aagccctgtc tatatctcct ttatgataca aattaactgc
     1141 caatgtcaat aatgcctcat tctctttgac agccagtttt gtatctgtca tagcagccag
     1201 cattagaaac ttttcttcca atgcataatt cccaatcaac cgataagctc tggcaagtcc
     1261 catagccatc atagcatagc catgagatgc cggctcttgt ttatcatata tctctgttaa
     1321 aatcagaaga gcctctttgg tacttccctt atcttgaagc ttcacagctt tttcttttct
     1381 atattcatcc gactggtcaa ataagatgct catcacagta tcccgataag cctctttttc
     1441 cgatatatac tcgtttgaaa accgtacatc gtccgtgtat ttaatgagat tttcataata
     1501 acgtatacga ttccagcaat acaaagcttt taaatgatcg ggtaaatccg cacattttat
     1561 cgacttaaaa atatcatttg cttgaataaa caaaccggat aaagaataga caaaagccaa
     1621 ccggagctgc tcttccaaaa gatattcttt attaccaatc gtttttgcta tatcaatatt
     1681 ctcatgaata tattgttctg ccgagtcaca gacaaaagtc tcatattgat ggataatctc
     1741 tttatttaaa ttgtatatat cctccaacga attaagacca actttctttt tctttaattc
     1801 ttttatggta gcttcttttt tctgggtata tatcaaacgt tcagaaatca ctttgtccaa
     1861 caccttcaac aaagaatcat tctcactatc tgcatagagg taaaacaagg agtttagaag
     1921 gaaaaatata aaccaaagtg tgcgtttcat aatcatgtat tctttcttaa tctgcaaaaa
     1981 aatgtatttt ctttgtgtta ttcgccaaaa agagcgtaaa tcattctttt tattgcatct
     2041 tttaacaaat gaagatggag aaattacccc attctaaatg atatttgtga aaccatgctg
     2101 actaaaaaat gaatctaaaa gatatggagt taaaaaaagc ttttttgcta tacggacttt
     2161 gcaaaaagta taaatattag ttctatattt gcagccgtta aaagagaaag atgaaacaaa
     2221 gcttaaaatt cggactactt ttagtgttgg ctttgctcat ccattgtgca actaatggag
     2281 caatggaaga tatgtgcaaa gtttcctccc cgacttatcg gcaggagaaa tgctatgtat
     2341 cacaagatcg tccgattcag gatgctttgg aacgtcttta taatctttat acgacgcaaa
     2401 cctgtgacat gagtcataca gacgtcgcac atgttccgac agataaaagc atgtttttgt
     2461 taatcgctta tttctgtgac cattacaaac atcaaagtcc accttaccca gtctcatccc
     2521 attctcctac atactattac gatcctatct cctattatat atatgggttg agaaagattg
     2581 tcatttagcc tacagtacag tagactcttt tgctcgtcat ttattacagt tggttttatt
     2641 ctccataggg cgaatagact aattgcttat ttctatataa tattcaatct taacagctat
     2701 tgaattatga attttacatt tttagttgtt gttttactga cagcgcttgc ttttgtcggt
     2761 gtagtaatag ccctctcgcg tgctatctct ccccgttcat acaacctgca aaagtttgag
     2821 gcttatgaat gtggtatacc gacacgtggt aaatcatgga tgcagttccg tgtaggctac
     2881 tacttgtttg ccatcctatt ccttatgttc gatgtcgaaa cagcttttct gtttccgtgg
     2941 gcggtagtta tgcgtgacat gggaccacag ggacttatta gtgttctctt cttctttatc
     3001 attttagttc tgggtcttgc ttatgcctgg aggaaaggag ctttggaatg gaaataacca
     3061 aaaagccaaa aataaaatct attccgtatg atgagtttat cgacaatgaa tcattggaaa
     3121 agttggtcaa ggaacttaat gcaggaggag ccaatgttgc cctcggagta cttgacgact
     3181 ttatcaactg gggacgcagc aattcactgt ggccgcttac ctttgcaacc agttgttgtg
     3241 gtatcgaatt tatggcactg ggtgccgcgc gttatgacat ggcccgcttt gggtttgagg
     3301 tagcacgtgc cagcccgcgt caggctgata tgattatggt atgcggaaca atcaccaata
     3361 aaatggctcc ggtactgaaa cgactttacg accagatgcc cgatccgaag tatgtggttg
     3421 ccgtaggcgg atgcgctgtc agcggaggtc ctttcaagaa gtcctatcac gtagtaaacg
     3481 gggtggacaa gattcttccg gtagatgtat atattcccgg atgcccgcca cgtcctgaag
     3541 cattctatta tggcatgatg caattgcaac gcaaagtgaa aatagaaaag ttctttggtg
     3601 gagtaaacag aaaagagaag aaaccggatt atttaagaaa tgaagaatga tgaatgatga
     3661 atgaagaatt cgcatgcaac atcccggcag atttttcatt cttaattttt cattcttaat
     3721 ttaatttgat ttatgcaaga aatacaattt atagctcctg cagcgttaca cgacgagatg
     3781 ctgcgcttgc gaaatgaaaa acagatggac tttctcgaaa gcctcaccgg tatggactgg
     3841 ggagtagccg atgagaaaga cgctccggaa aaactccgcg gcttaggcgt agtctaccat
     3901 ctggaatcta ccattacagg cgaacggata gcactaaaaa cagcgacaac caaccgcgag
     3961 ctaccggaaa ttccgtctgt cagcgacatc tggaagatag ccgacttcta cgaacgtgaa
     4021 gtttttgatt tttatggcat cacctttgtc ggtcatcctg atatgcgccg gctctacctg
     4081 cgcaacgatt ggatcggtta tccgatgcgt aaagataacg atccggaaaa ggataaccca
     4141 ctgtgcatga ccaatgaaga gacgtttgat acgactcaag aaatagaact gaacccggac
     4201 ggaaccatca agaacaaaga gacgaaactg ttcggcgaag aagaatatgt agtcaacatc
     4261 ggtccgcagc accctgctac ccatggtgta atgcgcttcc gtgtttctct ggaaggtgaa
     4321 attattcgta agattgatgc gaactgcggg tatatccacc gaggcatcga aaaaatgaat
     4381 gaaagcctca cttaccctca aacattggct ttgacagacc gtctggacta tttgggcgcg
     4441 catcagaacc gccatgcatt gtgtatgtgt attgaaaaag ccatgggcat tgaggtcagt
     4501 gaacgcgtac agtacatccg taccataatg gacgagttgc aacgtatcga ttctcacttg
     4561 ctgttttact cttgtcttgc aatggaccta ggagcattga cagcattctt ttatggattc
     4621 cgtgaccgcg agaaaattct cgatatcttt gaagaaactt gcggcggacg tctgattatg
     4681 aactacaata cgattggcgg cgtacaggct gatcttcatc ctaacttcgt caaacgagta
     4741 aaagagttca ttccatatat gagaggaatt atccacgaat atcacgatat atttacgggt
     4801 aacatcattg cacaaagccg tatgaaaggc gtcggtgtgt taagccgtga agatgccatc
     4861 tctttcggtt gtaccggagg tacaggccgt gcatcaggat gggcgtgtga cgtacgtaaa
     4921 cgaatgccat acggtgtata tgacaaagtc gatttcaaag aaatcgttta tacggaaggt
     4981 gactgctttg cccgttacct ggtgcgtatg gatgagatca tggaaagtct gaacatcatt
     5041 gagcaattaa tagacaatat tcccgaggga ccttatcagg agaagatgaa acctatcatc
     5101 cgtgttccgg aaggcagtta ctatgcagca gtagaaggaa gtcgtggtga atttggtgtc
     5161 ttcctggaaa gtcagggtga caaaacgcct taccgcctgc actaccgtgc tacgggattg
     5221 ccgcttgttg ctgcaattga caccatttgc cggggaacaa agattgcaga cttaattgct
     5281 attggcggaa caatagatta tgtcgttccg gatattgaca gataatactt aattattaaa
     5341 aatatatgtt cgactttagt atagtaacaa actggataca tgagctactg ctctccatta
     5401 tgccggaggg attagccatc tttatagaat gtgtagctgt cggcgtgtgc ctcgtagcac
     5461 tgtatgccat cctggctatc atattgatct acatggagcg taaggtctgc ggtttcttcc
     5521 agtgtcgtct tggaccgaac cgtgttggta aatggggttc tatccaagtg gtctgcgacg
     5581 tgctcaaaat gctgaccaaa gaaatcttca tgccgaaggg tgccgaccat ttcctttaca
     5641 atcttgctcc attcatggtg attatcgctt cattcctgac tttcgcttgt attcctttta
     5701 ataaaggtgc ggcgattctg gactttaatg taggcgtgtt cttcctgttg gcagcttcca
     5761 gcattggagt tgtcggtatc ttgctggccg gttggggtag taacaacaaa ttctctttga
     5821 ttggtgccat gcgaagtggt gcacagatta tcagttatga actttcggtt ggtatgagta
     5881 tcatgacaat ggtagtgctg acgggaacca tgcaattttc tgaaatcgta gaaggacaag
     5941 ctaatggttg gttcatcttc aagggacata ttcctgcggt cattgctttc atcatctatc
     6001 tgattgccgg aaatgcagaa tgtaaccgcg gtccgttcga ccttcctgaa gcggaaagtg
     6061 agctgacagc cggctatcac actgaatact ccggtatggg tttcggtttc ttctatctgg
     6121 cagaatactt gaatctgttt atcgtagcca gtgttgccgc cactatcttc ctgggaggat
     6181 ggatgccgct gcacattgtt ggtttggatg gatttaacac tgtaatggat tatattccgg
     6241 gctttatctg gttcttcgcc aaagcattct ttgtggtatt ccttttgatg tggatcaaat
     6301 ggactttccc acgcttgcgt atcgaccaga tcttgaatct ggaatggaaa tacctggttc
     6361 caatttctat ggtaaatcta ttattaatgg catgctgcgt agctttcggc ttccactttt
     6421 gataaatgta aattatggaa tataaagata aaaaatatac gtacttaggt ggtctggtgc
     6481 atggcatcag tacactgaca acgggtatga aaaccagcat caaggtatac ttccgtaaga
     6541 aagtgaccga gcaatacccc gaaaaccgga aagagctgaa aatgttcgac cgtttccgtg
     6601 gtacgctgaa tatgccccac aatgagaata atgaacatcg ctgtgtagct tgcggactgt
     6661 gtcaaatggc ctgtccgaac gatacaatca aagtgaccag cgaaaccgtc gaaacagaag
     6721 atggaaagaa gaagaaaatt ctggcaacct atgaatatga tttgggtgcc tgtatgttct
     6781 gccagctctg tgtcaatgct tgtccgcacg atgccatcac gttcgaccag aacttcgaac
     6841 atgcagtctt cgaccggacg aaacttgtcc tgaagttgaa ccacgacggt agtaaagtaa
     6901 tagaaaagaa aaaagaagtt tagatatggg atcaacactt gaaacagtag tattctactt
     6961 tttggcagca tttattattg ctatgtccat catgacggtg actacccaac gtatcgtacg
     7021 ctcggccacc tacctgctct tcgtgctctt cggcacggcc ggcatctatt ttttgctggg
     7081 ttacaccttt ctgggttccg ttcagattat ggtttatgcc ggtggtatcg tcgttcttta
     7141 tgtattctcc atcctattga ccagtggaga aggcgaccgg gccgagaaag caaaacgaag
     7201 taaagtctta gccggactct tcactatgat tgccggtttg gccattatcc tgtttatcac
     7261 actgaagcac gatttcatgc agacagctaa tttggccccg caagaaatta gcattcatgc
     7321 tatcgggaac gctttattaa gtagtgacaa atacggttat gtattgcctt tcgaagctgt
     7381 cagcatatta ttgctggcgt gtatcatcgg tggcatcatg attgcacgta agagatagga
     7441 attttaagta ttaactatca aaatagagtt cgaatatgat acacatggaa tattacctgg
     7501 tagtttctac catcatgatg tttgcaggaa tctatggatt ctttacccgc cgaaatacac
     7561 tggctatcct gatttctgta gagttaatgc tgaatgctac ggacatcaac ttcgccgtat
     7621 tcaatcgttt cctttttccg gggggaatgg agggttattt ctttgcactc ttttccatcg
     7681 ccatctcggc tgcggaaact gcaatagcta tcgccatcat gattaacatt tatcgtaatc
     7741 ttcgaagcat tcaggtgcgc aacctggacg agttgaagtg gtgatttgtt tcattcccag
     7801 gaacaaggtg tttcatccct tgaaacactt cgtttcacac cgagaaacaa agtgtttctc
     7861 accgaggaac aactagtttc acaccgggaa accaaacaga aggtccgagt atagtgatta
     7921 tcagctataa gaccaaaaat taataataat aactcaagta attaaataaa actgtatgga
     7981 actaacaatt ctaatactcc ttcttccttt cttctccttt ctcatattgg gaatcggagg
     8041 taaatggatg tcccaccgga cagcgggtac aatcggtacg ctgatactgg gagcagtagc
     8101 agtactatcc tacgttacag ctatccaata tttctccgct ccacgactgg aagacggaac
     8161 attcgccaca ctgatgcctt acaacttcac gtggcttcct tttacagaga ctttacactt
     8221 cgatttgggc atcttgctcg atcctatatc ggtaatgatg ttgatcgtca tctctacagt
     8281 gtcactgatg gtacatatct actctttcgg ttacatgaaa ggagaagtcg gttttcaacg
     8341 ctattacgct ttcctatccc tgtttaccat gtctatgctg ggattgggcg ttgcaaccaa
     8401 catcttccag atgtaccttt gttgggagct ggtgggggta agttcttacc tgctaatcgg
     8461 tttttattat acaaaaccgg ctgccattgc tgcttccaag aaagcgttta ttgttactcg
     8521 ctttgctgac ttgggcttcc tgatcggtat cctgatttac ggatattacg gtggtacatt
     8581 cggcttcact ccggatacaa tatccttgat aagcggtgga gcttctatgc ttccgttggc
     8641 tctcggactg atgtttgtcg gtggtgccgg taaaagtgcc atgttcccgt tgcatatctg
     8701 gttgccggat gcaatggaag gtcctactcc ggtcagcgca ttgattcatg cggctaccat
     8761 ggtagttgcc ggtgtatatc tggtggcacg tatgttccca cttttcatta catacgcacc
     8821 gaatacgctg cacatggttg cttgggtagg tgcatttaca gcattctacg cggcaagtgt
     8881 ggcttgcgta caatcagaca tcaaacgtgt actggctttc tctaccattt cacagattgg
     8941 cttcatgatg gtagctctgg gtgtttgtac ttccatgaat ccgcacgaag gaggtttggg
     9001 ctacatggct tccatgttcc accttttcac acatgccatg tttaaggcat tactcttcct
     9061 cggtgcaggt agcattatcc atgccgtaca ttctaatgaa atgtccgcta tgggaggttt
     9121 acgcaaatat atgccgatca ctcactggac attcctgatt gcttgtctgg ctattgccgg
     9181 tattcctccg ttctcgggct tcttctcgaa ggatgaaatt ctggctgctt gtttccaata
     9241 cagccctgta atgggatggg tgatgacagt catcgctgca atgacagctt tctatatgtt
     9301 ccgcctttac tacggtattt tttgggggag cgagccgccc cgggcaggtt cccattcgga
     9361 acataacacg ccgcacggaa acttggaagc ggcaccttgc cgcccacatg agagtccgtt
     9421 ggctatgact ttcccgctga tgttcctggc agttgtaact tgtggagcag gatttattcc
     9481 tttcggacac ttcatcagtt cgaatggtga atcttattct atccatctcg atccgtcagt
     9541 aactattacg agcgttgtta ttgcgattat ttcgattgca atcgctacat ggatgtacaa
     9601 gaatgccaaa cagcctgttg ctgattcgtt ggcaaaacga ttcaaaggtc tgcacaaggc
     9661 agcctataat cgcttctata ttgatgatat ctaccagttt attacgcata agattatctt
     9721 ccgctgcatc tctactccta tcgcatggtt cgaccgtcat gtagtggatg gattctttga
     9781 cttcctggca tgggccacca atacaacaag cgacgagatt cgtggtttgc agagcggtca
     9841 ggtacaacaa tatgcgtatg tgttcctttg cggtgcattg gcacttatcc tactgctgat
     9901 tctctaaata gtaaatagta aatctttaaa tagtaaatca taaagatgaa tttcttatcc
     9961 atattcgtac ttatcccctt attgatgctg gccggacttt gggcagcacg aggaatcaaa
    10021 gccatccggg gggttatggt tactggcgca tcggcacttc tgattgcctc cgtcgtactt
    10081 acattcctgt atctgggaga gcgtagcgcc ggaaatacgg cagaaatgct tttccgtgca
    10141 gatacgcttt ggtatgcccc gcttcacata tcttattcag taggtgttga cggaatttcg
    10201 gtagccatgt tgttattatc tgctgtcatc gtattcaccg gtacattcgc ttcctggcgc
    10261 ctgcaaccgc tgacgaaaga atatttcctc tggttcaccc tgttgtctat gggagtattc
    10321 ggattcttta tatccgtcga tttgttcacc atgttcatgt tctatgaaat tgcgttgata
    10381 ccgatgtacc tgctgattgg tgtatgggga tcaggacgta aagaatatgc agccatgaaa
    10441 ctgaccctta tgttgatggg cggttccgct ttcctattga tcggtattct cggaatctat
    10501 ttcggctcgg gagcaaccac catgaacctt ctcgaaattg cacagttgca caacatacct
    10561 tttgcacagc aatgcatctg gttcccgctg actttcctcg gcttcggtgt attgggcgcc
    10621 cttttcccgt tccacacatg gagtcctgac ggtcacgctt ctgccccgac tgccgtatcc
    10681 atgcttcatg ccggagtatt gatgaaactg ggaggttacg gatgtttccg tatcgccatg
    10741 tatctgatgc cggaagcagc caacgaactt tcctggatat tcctgatact gacaggtatc
    10801 tctgtagtct acggagcctt ctccgcttgc gtacagaccg acttgaaata tatcaatgct
    10861 tattcatccg tatctcactg cggactggtt cttttcgcca ttctgatgct aaaccagaca
    10921 gcagcaacag gagcaatcct tcagatgctt tcgcacggat tgatgacagc cttgttcttt
    10981 gctctgatcg gtatgatata tggacgtaca cacacacgtg acgttcgcga acttgccggt
    11041 ttaatgaaaa ttatgccgtt ccttagtgta tgttatgtga ttgccggtct tgccaacctc
    11101 ggtctgccgg gattaagcgg tttcattgct gaaatgacca tcttcgtcgg ctctttccag
    11161 aacaacgatg tatttcaccg tacactgact atcattgcct gttcttcaat tgtgattacc
    11221 gcagtctaca tcctgcgcct ggtaggtaag atcctatacg gaacctgcac caacaaacat
    11281 cacctcgaac tgactgatgc aacttgggac gaacgtgtag ccgttatctg cctcatcgtt
    11341 tgcgttgccg gactaggtat ggctcctttc tgggttagcc acatgattgg tgaaagcgta
    11401 ttaccggttg tctcacaact aatcccctaa ctcataaatc ataattctta attcataaat
    11461 aaacaagatg gattattcac aatttctaaa tatgcgagaa gagctgtcgc tcatagctgt
    11521 cttactgctg ctatttctag ctgacctctt catgagtccg gatgcacaca aaaatagtgg
    11581 gaaagcacgc ctgaacacca tgttgcccgt tattctgatg gctatccata cggctatcaa
    11641 cctgattccg ggaactgctg ccgatgcatt cggtggtatg tatcactatg taccgatgca
    11701 cacagttgtt aaatcgatcc tgaacgtcgg tacactgatt gttttcctga tggcgcacga
    11761 gtggatgaaa agagaagaca cttcattcaa acaaggagaa ttctatgtgc ttacactctc
    11821 taccttgttt ggtatgtatc tcatgatttc cgccggacat ttcctgatgt tcttcatcgg
    11881 tcttgaaact gcttctattc cgatggcagc attgattgct ttcgataaat accgtcacaa
    11941 ctctgccgaa gcaggtgcca aatacattct gacagctctt ttttccagtg cattgctgtt
    12001 gtttggtctg tccatgatct atggttctgc cgggactctt tatttcgatg acctccctgc
    12061 ccatatcgac ggaaatccgt tacaaatcat ggcatttata ttcttcttca caggaatggc
    12121 attcaagttg tcactggttc cgttccactt atggacagca gacgtttacg aaggcgctcc
    12181 gagtgcagtt accgcttatt tgagtgttat atcaaaagga tcggcagcat ttgtattatt
    12241 ggccgtcctt atcaaagtat tcgctccaat gattaatgac tggcaggaag tactttattg
    12301 ggtaaccatc gcttctatca ctattgcaaa tatatttgct gtccgtcagc aaaacctgaa
    12361 acgtttgatg gcgttctcca gtatttcgca agcgggatat attatgttag gcgttatcgg
    12421 aggcacagca caaggcatga cggcattggt atattatgta ttagtgtacg ctgccgccaa
    12481 cctcggagta tttgccgtta tcactatcgt ggcattacgc agtcagaaat tcacgctcga
    12541 agattacgca ggactttata aaacgaatcc caaaatcgct ctcttgatga ctctgtctct
    12601 gttctcattg gcaggcatcc ctccgtttgc cggattcttc tctaagtttt ttatcttcat
    12661 ggctgctttc gatgcaggtt tccacttgct ggtattcatc gcattggtaa atacagtgat
    12721 ttcgttgtat tactatctat tgattgtaaa agcaatgtac atcactcctt ccgacaaccc
    12781 aattcctact ttccgcagcg accgctgcac aaaatgggga ctggcacttt gcacgctggg
    12841 tatcatcgga ctgggtattg caagtattgt atatcaatct attgataaac tatcgttcgg
    12901 aatttaaact gactacacct ttgcaccaaa gaaacggtct
//
