LOCUS       c00079_gnlPro..        15196 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BEFLGIBF_79.
ACCESSION   c00079_gnlPro..
VERSION     c00079_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 23:39:48
            Original ID  :: gnl|Prokka|BEFLGIBF_79
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 5542
            Orig. end    :: 20738
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15196
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[15542:19473]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13931
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..15196
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15196
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(854..1216)
                     /locus_tag="ctg79_7"
                     /transl_table=11
                     /translation="MAKMLIEDFKGVVPSDIDELQKLPGVGRKTANVIASVVYDKPAMA
                     VDTHVFRVSNRIGLTNNSKTPLETEKELVKNIPEELIPIAHHWLILHGRYVCLARKPKC
                     EECGLKPWCKHFLKQT"
     CDS             complement(1459..1626)
                     /locus_tag="ctg79_8"
                     /transl_table=11
                     /translation="MEEGDRYFFIYSYNSGVSYFWHISACIFLLKVIPLGCEKQKPKKQ
                     CEKKKGIKAY"
     CDS             complement(1661..2011)
                     /locus_tag="ctg79_9"
                     /transl_table=11
                     /translation="MELYVLGFTATTKQDPQINEALMMYDMNLDTYKNLNPGEMIHIKC
                     DDINAVSFFLSGSNENLVSITGLSQDGEKNIVYQGNVGYIKLNKTMFEDFSSLEITTIG
                     KESIHIHQIVRE"
     CDS             complement(2225..4174)
                     /locus_tag="ctg79_10"
                     /transl_table=11
                     /translation="MKTLKYLLATMLLLGVCNLTHSQKLSLGIFPEPQEVTISSQTYAP
                     PHGYALRGINNPDADAVRLLKEALPFAKSGKSLPLEIKKLKDKAPEMQRSGAYTLTITK
                     KGITIGIVDDNSLFYAAQTLKQLVKYDEGKKILPLCSIKDYPDVLFRGTVEGFYGQPWS
                     HADRIEQIRFYGRIKLNTYIYGPKDDPYHSSPNWRKPYPAEEAEHIKELAKEASHNKVN
                     FVWAIHPGQDIQWNLTDSMNILSKFEKMYDLGVRSFAVFFDDISGEGARPEKQAGLLNY
                     IHKEFITKKNDVQPLIMCPTEYNRSWAKTDYLDILGTQLDPAIQIMWTGDRVVADITKE
                     GVEWVNNRIRRPAYIWWNFPVSDYCQDHLLMGPAYGLDTQAAGTMTGFVSNPMEYAEAS
                     KVAIFGVGMYTWNIENYDPTQAWKDACDFIMPEASMAFRIFCEHNCDPGPNGHQYRREE
                     SANYVAPIQTFLAGYKKNTFPEQSANLLGTLFAQITASPSMIYSQSPNKRLIEQINPWL
                     IQFEFLGKAGTSALHMAHAWYEKDRSYTWQRYLETSALLDSMKLINRTLNQKAQPKGVK
                     VGSKVLHPFIVDLYRQTGRNLLSTDGIAPDEVKVSIPSIFTNIDQLKSQPCAEGDNTVG
                     YVPLFEVVKVQPNQ"
     CDS             complement(4276..5859)
                     /locus_tag="ctg79_11"
                     /transl_table=11
                     /translation="MIKITYKLILLLSLLAMTVTSFAASEAEYGKVSKAWTLHADGSQE
                     YRSSMELTLFTHTAMNSTYGESFIVYNPDFQTLKIHSSYTRQKDGTIVKTPDNAFVEVL
                     PRFAADAPAYNQLKEMVVVHTGLELGATIYLDYSIITKPGYYPALDINERLQETSPVKE
                     CKVSISVPEGTPLACGLYGSPVKAVEESHDGIKEVHWTLRNIPASSREAFQPKNREASP
                     HLVASTYPSGKAALATLDKRLKESQGYESKTFAQFLTDKSGNEQEKVNIIRDHILNNLS
                     TCPIPMAMTGYTVRDIDTVLRSAYGTPLEIAQLLNVMLNAAGIPSEVLAVYPGHLDTDA
                     CGLAAIQTLAVKATVDGKDQYLSASPLTNRGGLDKVVSLSGTSIEIETTPIQIKESRSV
                     AISADQAKDGFAICVLPAISAGIDSWGMSALNSKRSNLFELPSLIREEVTYTVTPAEGM
                     KLQTSTQEQVISKPFGKVTRTITPRGNTIEVVRTIELNKQQFTPAEYSDVRSLIHEWTN
                     PDNRVLLFSL"
     CDS             complement(5873..7831)
                     /locus_tag="ctg79_12"
                     /transl_table=11
                     /translation="MKRILTITAVSLLALSPMYGQDSCRYPQDPTLEKSQAYAGYDCVT
                     LLDSTAVTVQPTGSGAFAVCKAFKVQTPKGAVANRIIKYDYDPLTAHAEFRYATIYRAN
                     GDVINLDVTGACDYAAPARAIYWGARQIMLEVGRLQPGDVVEYEIAKKGFTYALLTAGD
                     DERFIPPMRGQFYDIVPFWATEPTVRKVYRVSMPMEKELQFQFYQGECTSSMRYEDGRK
                     VYTFASDDILPFAKEPNMVDLFDAAAKLMMSSTPRWEDKSVWFNKVNEDYGSFTAIPEA
                     QRKVDELIKGKKTEMEKIAVLTHWVADNIRYSGISMGKGEGFTLHNLKMNYTDRCGVCK
                     DIAGTLIAFLRMAGFEAYPAMTMAGSRVESIPADHFNHCVAVVKLASGTYMPLDPTWVP
                     FCRELWSSAEQQQNYLPGVPEGSDLCLTPVSAPENHYVRIHADNRLDEKGTLRGQFTIT
                     AEGQSDSNIRRIFTTGWQSDWQNTMEKQLLAVSPNAKLLRVDYGKDPKNYQAAPIKITF
                     SYEIPDYAIIAGDQMLIKPLVMNNLYNQVKSFLRIDTKPENRAYGFKDACSRLVEQDET
                     IRLPKGYTLLNAPKNDALRSNAADFEGSLSQEGDRNIVLRQKLALKKRVYDAADWKGFR
                     SAVNAYKSYGDYLIIKK"
     CDS             complement(7834..8901)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 52.4; E-value:
                     1.1e-16)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg79_13"
                     /sec_met_domain="AMP-binding (E-value: 3.4e-17, bitscore:
                     52.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIQEDLQAFLAEWHDPSPFLEVQTSGSTGTPKRMRVRKDRMLNS
                     ARLTCDYLGLKKGDKALLCMPLRYIAGKMMVVRSLYAGLDLEVREPSGHPLADWGDTPL
                     RFAAMIPLQVYNTLRVPEERKRLEQTDILIIGGGAIDAALEQEIRQMPNTVYSTYGMTE
                     TLSHVALRRLNGPEASPYYHPFPSVTLSLSPDNTLVIDAPLVCDERLVTNDVARLLPDG
                     SFAIIGRKDNIINSGGIKIQIEEVEERLRPYLDLPYAITAAPDPRLGEAVVLLIAPRSC
                     ETVSPPRVTPHMKAIMSDSAQLSCEVSTVALASLPKYLRPRHVIEASEIPQTGSGKIDR
                     AACRELARNIITKTL"
     CDS             complement(8905..9963)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg79_14"
                     /sec_met_domain="MR_MLE_C (E-value: 2.7e-30, bitscore:
                     95.9, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKERFYKTEVVPRCLTFKRPAGTSRGVYTTRKLWEVRIRKEDEP
                     SVIGIGECAPLPDLSCDYGVDYEITLSKACLDLEQKGYVDTESLRHYPSILFGLEMAMR
                     HYEQGGWRHYDTPFSRGQAGIPINGLIWMGDYKYMLEQVEEKMKEGFRCVKLKIGAIDF
                     DRELSLLKHIRTHFSAKEIELRVDANGAFTPPEAMDKLKRLAEMDLHSIEQPIRAGQLE
                     EMAHLAAESPLPIALDEELIGCNAPDEKRRLLETIHPQYIILKPSLHGGISGCTEWIHL
                     AEAILGSTPEQPKWWVTSALESQIGLNAIAQWCATLGNPLPQGLGTGEIFKDDKHRLIQ
                     RKGDTIWFTNDL"
     CDS             complement(10001..10825)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_15"
                     /sec_met_domain="ECH_1 (E-value: 4.6e-82, bitscore: 265.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METKREWTTIKEYEEILFDFYNGIARITINRERYRNAFTPTTTTE
                     MSDAFYICRERPDINVVVLTGAGDTAFCAGGDMNVKGRGGYVGKDGVPRLNVLDVQKQI
                     RSLPKPVIAAVNGFAIGGGHVLHVVCDLTIASENAIFGQTGPRVGSFDAGFGSSYLARV
                     IGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLDKLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATMLYYMTDEAQEGGKAFLEKRRPRFEDYPKFP"
     CDS             complement(10829..12373)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_16"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-07, bitscore:
                     22.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTDERSAGFFAVGLALHGGKPAAVCCTSGTALLNIHPAVAEAFYQ
                     KVPLVVISADRPAAWIGQMDGQTLPQPGVFGSLVKKSVQLPEIHTDQDEWYCNRLINEA
                     LLELNHHGKGPVHINVPISEPLFQFTTPELPKVRVITRYQGLNVYDRKYDDLIERLNKY
                     SKRMMIAGQMSLIYLFEKKICKLLYKHFTWLSEHIGNRIVPGLPIKNFDAILYATPEEE
                     KEKLVPELVITYGGHIVSKRLKEFLRKHPPKEHWHVSLDGEVADLFGSLTTVIEMDAFE
                     FLEKIAYMLENRQIEYPKAWEYKSRNLPEPEFAYSEMAAIGGLIRSLPAESALHLGNSS
                     TVRYAQLYTVPETVEVCCNRGTSGIEGSLSTAIGYASASQKLNFIVIGDLSFFYDMNAL
                     WNGNLHNNLRILLLNNGGGEIFQALPGFKMNERTHRYVTASHQTSAEGWATERGFSYSA
                     VHNAEELAAAMSAFTQTEQPSEHPLFMEVFTDKAEDVRLLKEYYHQLKNSSQAQNI"
     CDS             complement(12532..13110)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg79_17"
                     /sec_met_domain="Chorismate_bind (E-value: 9e-47, bitscore:
                     150.0, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGTPEILLSGEKGDWQTVALAGTQSLRDGKLPKSWDHKNWREQQ
                     LVASYIRRQLSTLGITPEEKGPYSARAGEVSHLKSDFFFSLPNPEKLGDVLQLLHPTPA
                     VCGLPKEEAYHFIIENEGYDRSYYSGFIGWLDPKGKTDLYVNLRCMNILPQTFTLYAGG
                     GLLAASQLEDEWQETEDKLDTMRRIVGNL"
     CDS             complement(13626..13931)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_18"
                     /sec_met_domain="HBT (E-value: 1.1e-18, bitscore: 57.8,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVDERTRQPFGILHGGATLALAETVAGLGSMILAKPDEMVVGMQ
                     VSGSHMSSAHEGDTVRAVGTIIHKGRSSHVWNVDIFTSTDKLVSSVRVINSILKKK"
     CDS             complement(15117..15194)
                     /locus_tag="ctg79_19"
                     /transl_table=11
                     /translation="KAKADRITQYTNDEDGVARFIQELL"
ORIGIN
        1 gccacggcct cgtcatgact gacttgtgtc gtggttttta tttgcgggaa tagccgattg
       61 atccgggtgg ttatcgtatc gcataaattg gggtaaaagt tctccaaggc tttctcatag
      121 ggttgctcgt tgaagcagca aaggcttcct tcattataga ataaatccat tgccaaccat
      181 tgatttttca ttctccactc cgtcgagtca ttcatttgta cccgtaaata taaaggggcg
      241 cttttgatga agagattcat tgcgccacgc ttgccttttt tacgaatcag atctgttagt
      301 tccggaatga catgtgcggg gtatgtctgt tgcctttcca ccgtctctac caataatctt
      361 cggttgtagg acgctacgaa tataccctcg tggtagtaac aacctagaaa atgcttatca
      421 acatcaggat aatatctaac aggaacggag gtttcctctc gttgctgggc cggaaaagtg
      481 aaagagacgt ccagttgctt gaaaatacgc tctgccgtat gactatccat aggggcgtac
      541 aagacatccc cttgtggata ataagcgatt aggaaagacg ataattccag attttgccgt
      601 attaaagaaa ggaaaatagc gggggtatga tctgagaacg ccttgcgtat attctccatg
      661 ggtagtatca tcttctcgaa tacaggagga cgattgatgg caaaaattgc cgtggggctt
      721 ggaacgacca aactataggg atctaccgta gcgacaaatt gctcgtcgtt catatgcttg
      781 taaaagtacc tcacgcatac gatcgtaccc agaaacaaga caaaaaatgc cgttatgtct
      841 ttcttgctga tcctcatgtt tgctttagga agtgtttaca ccaaggcttt aatccgcatt
      901 cctcacattt cggtttccgg gcgaggcaaa catatcttcc atgcaatatc aaccagtgat
      961 gggcgatggg gatcaattct tccggaatgt tcttcaccaa ctccttttcc gtttccaaag
     1021 gtgtcttgct attattggtc aagccgatcc ggttggagac acggaatacg tgcgtatcca
     1081 ccgccatggc cggcttgtca tatactacgg atgcgattac gttcgctgtt tttcttccta
     1141 cgcccggcag tttttgtagc tcatcaatat cggagggaac cacgcctttg aaatcctcta
     1201 tcagcatttt cgccatacct accagatgtt tagccttatt gttcgggtaa gatacgcttc
     1261 gtatgtattc aaagacaact tccggtgtgc tagccgccat tacctcagga gtcgggaaag
     1321 cctcgaacag ggcaggtgtg atcatattca ctcgcttatc cgtgcattgt gcggatagga
     1381 ttaccgctat caatagttga taggggtcgt cataatgtag ttcagtctcg gctaccggta
     1441 cgttttcctt aaaccagttt aatacgcctt tatacctttc ttcttttcgc attgcttttt
     1501 cggtttctgt ttttcgcatc ctaaaggtat aacttttaat aggaatatac aagcggagat
     1561 gtgccaaaaa taagatacac ccgaattgta cgaataaata aaaaagtacc gatctccttc
     1621 ttccatctaa gagagaaaga aatcggtact tttttattta ttattcccta acgatctggt
     1681 ggatatgtat agattctttt cctattgtgg tgatttctaa agaagagaaa tcctcgaaca
     1741 tggttttatt taatttgatg tagcctacgt ttccttgata gacgatgttt ttctcgccat
     1801 cttgggagag gccggtgatg gataccagat tctcgttact tccggagagg aagaaagata
     1861 cggcgttgat atcatcacat tttatatgaa tcatttctcc cgggttcaag ttcttatacg
     1921 tatctaggtt catatcgtac atcataagag cctcattgat ttgcgggtct tgtttggttg
     1981 tcgccgtgaa tcctagtacg tatagctcca tttgctgatc cgagttattt cgcatacgga
     2041 tataacgggc tttcgggtcg atggtgcgga tcgtatcttt agcgttttcc gtggagacat
     2101 gagggattag gctccagctc tttccgtcgg cggaccactc gaatacccgt ccgggttggt
     2161 tgcttttcgg aagtttgaaa cagaagtatt cctcttcttt ctggatttcc cagccgataa
     2221 ccagttattg gttaggttgt accttgacta cctcgaatag gggaacgtaa ccgaccgtat
     2281 tgtcaccctc ggcacaaggc tggctcttta attggtcgat attcgtgaat atggaaggga
     2341 tgctaacctt cacctcgtcc ggggcgatac cgtccgtaga tagcaggtta cgacctgtct
     2401 ggcggtataa gtctacgatg aaagggtgta agactttcga tccgactttc acgcctttag
     2461 gctgcgcctt ctggttcagc gtgcggttta tcagtttcat gctatctagc aaagcggatg
     2521 tttccagata gcgttgccac gtataagacc ggtctttctc ataccaagcg tgcgccatat
     2581 gcagagcgct tgttccggct tttcctaaga actcgaattg gataagccat ggattgattt
     2641 gctcgatcaa gcgtttattg ggactttggc tatagatcat actcggggaa gccgtgattt
     2701 gagcgaataa ggttcccaga agattcgcgc tttgctccgg gaacgtgttt ttcttatatc
     2761 cggcgaggaa tgtctggata ggagccacat agttagcgga ctcttcccgg cggtattgat
     2821 gtccgttcgg acccggatcg cagttatgct cgcagaaaat gcggaaagcc atggaggcct
     2881 ccggcatgat gaagtcgcaa gcgtctttcc atgcctgtgt aggatcgtaa ttctcgatat
     2941 tccaagtgta cattccaacg ccgaatatag cgaccttgga agcctcagcg tattccatag
     3001 gattggatac gaatccggtc atggtgccgg cggcttgcgt atctaggccg taggcgggtc
     3061 ccatcaacaa atgatcttgg caataatcgc ttacggggaa gttccaccag atataggcgg
     3121 gacgacggat acggttgttt acccactcga cgccttcttt cgtgatatcg gctacgacac
     3181 ggtctccggt ccacatgatt tggatagcgg ggtcgagttg ggtaccgagg atatccagat
     3241 aatcggtctt agcccatgag cggttgtatt cggtagggca catgatcagg ggctgcacgt
     3301 catttttctt ggtaataaac tccttatgga tgtaattcaa taagccggct tgcttttccg
     3361 ggcgggctcc ctctccggat atatcatcga agaaaacggc gaaagagcgt acgcccaaat
     3421 cgtacatttt ctcgaatttg gaaaggatat tcatgctatc tgttaggttc cattgaatgt
     3481 cttgtcccgg gtggatggcc caaacgaagt tcaccttgtt atgggaggcc tctttcgcta
     3541 gttccttgat atgctcggct tcctcggcgg gataaggttt gcgccagttg ggggaactgt
     3601 gataaggatc atctttcgga ccatagatat aggtgttcag cttgatcctt ccgtaaaagc
     3661 ggatttgctc gatacggtcg gcgtggctcc aaggctgtcc gtagaatcct tccacggtac
     3721 cccggaataa tacgtccgga tagtccttga tcgagcagag aggcaggatc ttcttaccct
     3781 cgtcatactt gaccaattgc ttgagggttt gggcggcgta gaacaaggaa ttatcgtcta
     3841 cgatcccgat cgtgatacct tttttagtga tcgtcagcgt ataggcaccc gagcgttgca
     3901 tctccggggc tttgtctttt agcttcttga tctctaaggg gagggatttg ccggatttag
     3961 cgaaaggtag cgcttcttta agtagtctga ctgcgtctgc gtccggatta tttatgcctc
     4021 gtagggcgta tccatggggc ggcgcgtatg tctggctgga gatagttacc tcttggggct
     4081 cggggaagat tcctagagat agcttttggc tatgcgttag gttacaaacg cctagaagga
     4141 gcatggtggc gagtaaatac tttagtgttt tcatatgcga tatgatttaa tgttaacgtt
     4201 cgtaaatgta tgaaataatt aaacacggag cacacggaat acacagattt gttccgtgcc
     4261 ctccgtattt agatcttata gggagaatag caatacccgg ttatccggat ttgtccattc
     4321 atggatcaag ctacgcacgt cgctatattc ggcgggagtg aactgttgct tgttcaactc
     4381 tatcgtacgt accacctcga tcgtatttcc tcttggtgtg atcgtgcggg ttactttacc
     4441 aaaaggcttg cttatcactt gctcttgcgt ggaggtctgc aacttcatgc cctcggcggg
     4501 agtaaccgtg tatgttacct cttccctgat tagggagggg agttcgaata agttggaacg
     4561 cttgctgttc aaggcactca tgccccagct atcgattccg gcggagatgg ctggcaatac
     4621 gcagatggcg aaaccgtctt ttgcttgatc ggcggagatg gccacggatc tactttcctt
     4681 aatctgaata ggtgtggtct caatctcaat ggaagttccg gagagggaga ctaccttatc
     4741 tagtccgcca cgatttgtca gcggggaggc ggataggtat tggtctttcc catcgacagt
     4801 ggcttttacg gctagtgtct ggatggcagc cagcccgcaa gcgtccgtat cgagatggcc
     4861 gggatagacg gcgaggactt ccgacgggat tccggcggca ttcaacatca cgttcaagag
     4921 ctgtgcgatc tctagcggcg taccgtaagc actgcggaga acggtatcga tgtcacggac
     4981 ggtatagccg gtcatcgcca tggggatagg acaggtactg agattgttga gtatatggtc
     5041 tcggatgatg ttcaccttct cttgttcgtt accgctttta tcggtgagga attgggcgaa
     5101 ggttttgctc tcgtatccct gcgattcctt taagcgctta tccaaagtgg ctaaggccgc
     5161 tttacctgaa ggataggtag aggctaccaa gtggggtgaa gcctcacggt tctttggttg
     5221 gaaagcctca cgggaggaag cgggaatgtt ccgtagtgtc cagtgtacct cctttatacc
     5281 gtcatggctc tcttccacgg cttttacggg ggagccgtat agaccgcaag ccaagggggt
     5341 cccttccggt acggaaatag agaccttgca ttccttcacg ggagaggtct cttgtagtcg
     5401 ctcgttgata tccagagccg gatagtagcc cggttttgtg ataatagagt aatccaagta
     5461 aatcgtggcc ccaagttcta ggccagtgtg taccacgacc atttccttga gttggttata
     5521 ggccggagcg tcggcggcga aacggggcag gacctccacg aaggcgttat cgggtgtctt
     5581 tacgatcgta ccgtctttct gcctcgtata ggatgagtga atcttcagtg tttggaaatc
     5641 gggattgtag acgataaaac tctcgccata cgtgctattc attgcggtat gcgtgaagag
     5701 cgtcaactcc atggaggatc gatattcttg gctgccgtcg gcatgcaagg tccaagcttt
     5761 cgatactttc ccgtactcag cctccgatgc ggcgaatgaa gtaaccgtca tcgctaacaa
     5821 gcttaggaga agaatcagtt tataggttat cttaatcatt gtctttcttt ttttatttct
     5881 tgataatcaa atagtcacca taactcttat aggcgttcac ggcggaacgg aagcctttcc
     5941 agtcggctgc gtcgtagaca cgcttcttca acgctagctt ctggcgcaag acgatgttcc
     6001 ggtcgccttc ctgtgaaagg gaaccttcga aatcggccgc attgcttcgc agggcgtcat
     6061 tcttcggggc gttcaggagg gtatagcctt tggggagacg gatggtctca tcttgttcta
     6121 ccaaacggga gcaagcgtcc ttgaatccat acgcacggtt ttccggtttc gtatcgatac
     6181 gcaagaaact cttcacttga ttgtagaggt tattcatgac tagcggcttg ataagcatct
     6241 ggtctccggc gatgatcgca taatcgggga tctcataaga gaacgtgatc ttgatagggg
     6301 ccgcttgata gttcttcggg tccttaccgt aatctacacg aagcagtttg gcgttggggg
     6361 atacggccag caattgcttc tccatcgtgt tctgccagtc ggattgccat ccggtggtga
     6421 agatgcggcg gatattgctg tcggactgtc cctcggcggt gatcgtgaat tgtccgcgga
     6481 gcgtgccttt ctcgtctagg cggttgtcag cgtggatgcg gacgtagtgg ttttctgggg
     6541 cggagacagg ggtcaggcag aggtcggagc cttcgggcac acccgggagg tagttctgct
     6601 gttgctcggc gctactccat aattctcggc agaaaggaac ccaagtcggg tcgagaggca
     6661 tatacgtgcc gctagccagt tttaccaccg ccacgcaatg gttgaaatgg tcggcgggga
     6721 tgctttctac acggcttccc gccatggtca tcgccgggta agcctcgaat ccggccatgc
     6781 ggaggaaggc gatcaacgta ccggcgatat ccttgcagac accgcaacga tcggtataat
     6841 tcatctttag gttgtgaagc gtgaaaccct cgcctttacc catcgagatt ccggagtaac
     6901 ggatgttatc ggctacccag tgggtcaata cggctatctt ctccatttcc gtcttcttgc
     6961 ctttgatcag ctcgtctacc ttcctttggg cttccgggat cgcggtaaag cttccgtaat
     7021 cctcgttaac cttattgaac catacggatt tatcttccca gcggggcgtg ctggacatca
     7081 tgagcttcgc ggcagcgtcg aataggtcta ccatattcgg ttccttggcg aaaggaagga
     7141 tatcgtcgga ggcgaaggta tatactttcc gtccatcctc atatcgcatg gaagaggtac
     7201 attcgccttg gtagaactgg aattgcaact ctttctccat cggcatggat acccggtata
     7261 ccttacgcac ggtaggctcg gtagcccaga aggggacgat atcgtaaaac tgtccccgca
     7321 taggagggat gaaacgctcg tcgtcgcccg ccgtcagcaa ggcgtaggtg aaacctttct
     7381 tggcgatctc gtactccacg acatctcccg gttgcaggcg gcccacttcc agcatgatct
     7441 gccgggcgcc ccagtagatg gcacgtgcgg gggcggcata gtcgcaagcc ccagtcacgt
     7501 cgagattgat cacgtcgcca ttcgcacggt agatcgtggc gtaacgaaac tcggcatgcg
     7561 ccgtcagcgg gtcgtaatcg tatttgatga tacggttggc gacggctccc ttgggagtct
     7621 gtaccttaaa agccttgcat acggcgaaag cccccgagcc ggtaggttgt accgtgacgg
     7681 cggtgctgtc cagcaaggtg acgcagtcgt atcctgcgta ggcttgcgat ttctccaagg
     7741 taggatcttg cgggtatcgg caagaatcct gcccgtacat aggcgataag gccaataggg
     7801 agaccgcggt gattgttaga atccttttca tgtttatagt gtttttgtga tgatatttct
     7861 cgctagctcc cggcaggcgg cacgatcgat cttgccgctt ccggtttggg ggatctcgct
     7921 tgcctctatg acgtgccttg gacggaggta cttgggcagg ctggcgagag ccactgtcga
     7981 tacctcacat gatagctgcg cggagtcgct catgatagct ttcatgtgtg gtgtcacccg
     8041 agggggtgat accgtttcac atgaccttgg ggcgattagt aagactaccg cctctcccaa
     8101 ccgagggtcg ggggcggcgg tgatggcata ggggaggtct aggtagggcc gtagccgctc
     8161 ttccacctcc tcgatctgta tcttgatacc tccgctattg atgatattat ctttccttcc
     8221 gataatggcg aaactcccgt ccggcagcag gcgggcgaca tcgttcgtca ccagccgctc
     8281 gtcgcaaacc aatggggcgt ctatcaccaa ggtattgtcc ggcgacaagg ataacgtcac
     8341 cgaggggaag ggatggtaat agggcgaggc ttccggcccg ttcagccggc gcagggcgac
     8401 gtgagacagc gtctccgtca ttccgtaggt ggaataaacc gtgtttggca tctgccgtat
     8461 ctcctgttcc aaggccgcgt cgatcgcccc gccgccgata atcaggatat ccgtttgctc
     8521 cagccgttta cgttcctcgg gtactcgcaa cgtattgtaa acctgcaagg ggatcatggc
     8581 ggcaaagcgc aggggcgtat ccccccaatc cgccaacggg tgtccggagg gttcacgcac
     8641 ctccagatcc agtccggcgt atagggagcg gaccaccatc atctttccgg ctatatagcg
     8701 caggggcata cataacaggg ccttgtcgcc cttcttaaga cccagataat cgcaggtaag
     8761 ccgggcgctg ttcagcatcc ggtccttgcg cactctcatc cgcttgggcg taccggtgga
     8821 gccggaggtc tggacttcca gaaaagggga gggatcgtgc cattcagcta agaatgcctg
     8881 taaatcttct tgtatcggca taggtcaaag gtcgttggtg aaccagatgg tgtctccttt
     8941 tcgttggatc aaccgatgtt tatcatcctt gaaaatctcg ccggttccca gaccttgcgg
     9001 tagcgggtta cctaacgtgg cgcaccattg ggcgatagcg ttcagtccga tttgcgattc
     9061 cagagcggag gtgacccacc atttaggttg ttcaggggta ctccctaaga tagcttccgc
     9121 taagtgaatc cattccgtac atccggagat acctccgtgg agggaaggct ttaatataat
     9181 gtattgggga tggatagttt ccaacaaccg ccgtttctcg tccggggcgt tacagccgat
     9241 cagttcctcg tcgagagcga tgggaagggg tgactctgcc gcaaggtgtg ccatttcttc
     9301 caactgcccg gcacggatag gctgctcgat ggaatgtaag tccatctcgg cgagccgctt
     9361 cagtttatcc atcgcctccg ggggagtgaa agcgccgttg gcatctaccc gaagctctat
     9421 ttccttggcg gagaaatgcg tgcggatatg tttcaataaa gagagttccc ggtcgaaatc
     9481 gatagcgccg atcttcagct tgacgcagcg gaagccctcc ttcatctttt cctctacctg
     9541 ttccagcatg tacttataat cgcccatcca gatcagtccg ttaatgggga tgcccgcttg
     9601 cccccgcgag aagggcgtgt cgtaatgccg ccaaccaccc tgttcataat gacgcatggc
     9661 catttccaat ccgaaaagga tggatgggta atggcgcaaa gattcggtgt caacatatcc
     9721 cttctgttcc agatcgaggc aagccttgga taacgtgatc tcgtaatcca ctccataatc
     9781 gcaactgaga tccggcaggg gggcacattc tccgatacca ataaccgagg gttcgtcttc
     9841 cttgcggatt cggacctccc acaatttccg ggtcgtgtaa acaccccgtg aggttcctgc
     9901 cggtcgcttg aaagtcaagc accggggaac cacctctgtt ttataaaacc tctccttcac
     9961 cattcattct caattttcaa ttctcaattc tcaattccct ttacgggaac ttcgggtaat
    10021 cctcgaagcg tggacggcgt ttctccaaga atgccttgcc gccttcctgc gcctcgtccg
    10081 tcatatagta aagcatggta gcgtctccgg ccaactcttg tataccggcc tgtccgtcca
    10141 actcggcgtt caagcccgcc ttgatcatgc gcaaggccaa cgggctaagc aacatcatct
    10201 cctcggccca ttgaacgtac tcgtcctcta atttatccaa ggggactacc ttatttacca
    10261 gacccatatc caaagcctcc tgtgcattgt acttgcggca taggaaccag atctcacggg
    10321 cctttttttg tccgatcaca cgggcgaggt aagaagagcc gaacccggcg tcgaagctac
    10381 ccacacgagg gcctgtctgt ccgaagatag cgttctcgga agcgatcgta aggtcacaaa
    10441 ccacgtgcaa tacgtgtccg ccgccgatag cgaaaccgtt cacggctgcg atgacgggtt
    10501 tcgggagaga gcggatctgc ttttgtacgt ccaatacgtt caagcgaggt acgccgtctt
    10561 tacccacgta gccgccacgt cctttcacgt tcatatcgcc tcccgcgcaa aacgccgtat
    10621 ctccggctcc tgtcagaacg actacgttaa tgtccggacg ttcccggcag atgtaaaagg
    10681 cgtcgctcat ctccgtggtc gtagtcgggg taaaagcgtt gcgataccgt tcccggttta
    10741 tcgtaatgcg ggcgatgccg ttgtagaaat caaataagat ctcctcgtat tccttgatgg
    10801 ttgtccattc tcttttcgtt tccatatatt atatgttttg tgcttgggat gaatttttta
    10861 gttgatgata atattccttg agcaatcgta cgtcttccgc tttgtccgtg aaaacctcca
    10921 tgaatagggg atgttcgctc ggttgctccg tttgggtaaa ggcgctcatc gcagctgcca
    10981 actcctcggc gttatgaacg gcggagtagg agaatcccct ttccgtggcc catccctccg
    11041 ctgaggtctg gtgggaggcg gtgacgtaac ggtgcgtacg ctcgttcatc ttgaatcccg
    11101 gcaaggcttg gaagatctcg ccacctccgt tgttcaagag caggatgcga aggttattgt
    11161 gcaagtttcc gttccacaat gcgttcatat catagaagaa actaagatcg cctataacga
    11221 taaagtttag tttttgcgag gccgaggcgt atccgatggc cgtagacaaa gagccttcga
    11281 tcccgctcgt acctcggtta caacaaacct caaccgtctc gggtacggtg tacaattgcg
    11341 cgtaacgtac ggtggagcta ttccccagat gcaaggcaga ttcagccgga agcgaacgta
    11401 tcaaaccacc gatcgccgcc atttcggagt aagcgaactc cggctccggc agattccggg
    11461 atttatattc ccaagccttc ggatattcaa tctgcctatt ctccagcata taagcgattt
    11521 tctccagaaa ctcgaaagcg tccatctcga tcaccgtggt caggctaccg aataaatccg
    11581 ctacctcccc atccaatgag acatgccaat gctccttagg cgggtgtttc cgcaaaaact
    11641 ctttcagccg cttggagaca atatggccgc cgtaggtgat cacgagctcg ggaaccagct
    11701 tctctttttc ctcctctggg gtagcgtaca ggatggcgtc gaaattcttg atcggcaatc
    11761 ccggtacgat acggttgccg atgtgctcgg agagccaagt gaaatgcttg tatagtaact
    11821 tgcatatttt cttctcgaag agatagatca agctcatttg tcccgctatc atcattcgct
    11881 tgctatattt gttcaaacgc tcgatcagat cgtcatattt ccggtcgtac acgtttaggc
    11941 cttgataacg ggtgattacc cgtaccttcg gcaattcggg tgtcgtgaac tgaaataaag
    12001 gctcggagat cgggacgttg atatgaaccg gccctttgcc gtgatggttc agttccaaca
    12061 aagcctcgtt gatcaatcga ttacaatacc attcatcttg atccgtatgt atttccggta
    12121 gctgtaccga tttcttcacc agcgagccga acaccccggg ttgcggcaag gtctgtccgt
    12181 ccatttgccc gatccatgcg gcggggcggt cggcggatat cacgacaagc ggaactttct
    12241 gatagaaagc ctccgctacc gccggatgta tattcagcaa ggccgtgccc gaggtacagc
    12301 aaacagccgc cggcttacct ccgtgcaacg ctagccctac ggcaaagaat cccgcgcttc
    12361 gctcatccgt cacggaatgg caattgaaga acgaatggtt tgccaatgtg tgcacaatcg
    12421 gagagttccg gctccccgga catagcacga tattacttac gccgtgctct atcagcaagg
    12481 ctaccaattg aaggatgttc tttttatcgc tatacattat atgatataaa attataaatt
    12541 acccactatt ctccgcatcg tatctaattt atcctctgtc tcctgccact catcctctag
    12601 ctgcgaggcc gccaacagac cgcctccggc atacagcgta aaggtttggg ggaggatatt
    12661 catgcaacgg aggtttacgt acagatctgt tttgcctttg ggatccagcc aaccgatgaa
    12721 accggagtaa tagctacgat cgtacccctc attctcgatg atgaaatgat aagcctcctc
    12781 cttgggaaga ccgcaaacgg ctggagtagg gtgtaatagt tgaaggacat cacccagctt
    12841 ctcgggattc ggcaaggaga agaagaaatc gcttttcaaa tgggaaacct ctccggcccg
    12901 ggctgaataa ggccccttct cctcgggagt aatacccaag gtggacagct ggcggcgtat
    12961 ataggaggcg actaattgct gttctctcca attcttatgg tcccagcttt tcggtaattt
    13021 cccgtctcgt aaggattggg ttccggccaa agctaccgtt tgccagtcgc ctttctcgcc
    13081 ggataacaag atttccggtg tcccacccat ccaagttccg gtttccgggg tatggcaaag
    13141 gtagacatag gagcggatat atcgttctac tgcggcgaag aatgccttgc cgggtgagaa
    13201 agagggatct ttccggatcg ttttgctacg ggataggact agtttatctt ggcttccttt
    13261 tagcaaaggg ctggtaaaca gggagaaatg gtaagcgtat cgttccttct cctcggattc
    13321 ggatgggatt tcgatttcat tcgaagggaa ttcgtttttc tctcgagaga aatcccaatc
    13381 ggattcggag gggatttcaa agcaatccgg ttggattaaa acgataggtc gttccgctgt
    13441 cacctgaaac ggagcgatta caaaaccgct ccgttcattt aagtctttta tgtcgtataa
    13501 taggcaagga gagccggcgc tttgcatcct gaaatggagc ctatcctcac cgggaatacg
    13561 ccaaatagcg aaactccggc cttgcttgat caacgtgtct attatttcgt aagaatctct
    13621 tggaatcatt tcttctttag tatgctattg attacccgta ccgaggaaac cagtttgtcg
    13681 gtagaggtga atatgtctac gttccacaca tgggatgaac ggcctttgtg gataatcgtc
    13741 ccgacggcac gtaccgtgtc tccctcgtgg gcggacgaca tatggctgcc gctaacttgc
    13801 atgccgacta ccatctcgtc cggtttcgcc agaatcatgg aacctagtcc ggccacggtc
    13861 tccgccaaag ccagcgtagc gcctccgtgc aagataccga aaggctggcg ggtccgttcg
    13921 tctacaggca tggtcgcttc cacacgatcc tccgacgcat aggtatattg aatgcctaga
    13981 ttacccatta aggcatgttt ggcccgtgcg tttagttgat ctaacggaac ctccgtgggt
    14041 ttgatcgtgg caaggatcgc tttctcgatc gctaccgcca caccacccat attattagat
    14101 aaggtcgtga aatcggcgca agcctttacg gagtcgcgtg cgttacccat cgccacgccg
    14161 gtaccggcta attgaagcat ggatacgtcg gctacgccat caccaatagc gacaacctct
    14221 tcggtcgtga tattcagcat ctccatcaat accgccaacg tatttccctt attgatgaaa
    14281 tgaggagcta cctccaagaa atagtcctcg gagcggaaag cttccaatac cccgtccaga
    14341 cgtttcttcc aatgattttc gagacccact agattgttct cgtcatcgct ggtaagaata
    14401 cacttacagg gtgcgaaatc caccgcttcc gggaaattct ccacaccgat gatgcgcatc
    14461 ttattgagtt cggcctcctc ttggacatgc ttgttttccg ggctatcggt caggatatag
    14521 tccttgtgat acgtgaagat agcaaaaccg ttttccttcg ccttccggtt caaataagga
    14581 atcatggccg gatcgattcg tttctcgaac atcaattctc cggtctgggc attgatgatc
    14641 tgacctccgt tataagataa tatgaaacca ccgtaatgat tcaattcaag agcctccgcc
    14701 aagggttgaa ccccgttggt gggtcggccg gatgccaata caacatgaac tcccatctgc
    14761 tgagccttta acagggcggc atgggtccgg ggagttatct ctttcttgtc gttaagcaac
    14821 gtcccatcta cgtctaagac taataatttg tacttcatgg cgtcttattt tatggtttag
    14881 aatacaaatg tacataaaat agttgatagt tagaagacat ttccatgaaa ggaatttacg
    14941 tatatcggcg caagctcacg cctatatcgg tgtagccttg cggcgatata cgtacaggct
    15001 tatgccgata taggcattgg cctgtgtcga tactggtgta aatgtctctg aaaaaacacg
    15061 tacgtgttct tgcgaaaaca tgtacgtgtt tctcggaaaa tacgtacgtg tttttttcaa
    15121 agcaattctt ggatgaaacg agccactcca tcctcatcgt tcgtgtattg ggtgatgcgg
    15181 tcggctttgg ccttga
//
