LOCUS       c00095_gnlPro..        11294 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JDOKOADA_95.
ACCESSION   c00095_gnlPro..
VERSION     c00095_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:52:25
            Original ID  :: gnl|Prokka|JDOKOADA_95
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11294
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11294
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1111:7229]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1112..7229
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..11294
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11294
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="acetate2butyrate"
                     /region_number="1"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             969..1133
                     /locus_tag="ctg95_1"
                     /transl_table=11
                     /translation="MKILIKNFFIILLQSKEDCDKINTYRTRNALAKQLSNNIDNLNGG
                     MKLWQRKLY"
     CDS             1112..2293
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_2"
                     /sec_met_domain="Thiolase_N (E-value: 3.7e-104, bitscore:
                     337.3, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 7.5e-51, bitscore:
                     160.7, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKVVLAGACRTAIGTMGGGLSTVPAADLGSIVIKEALKRTNVP
                     ADQVDEVLMGCVIQAGLGQNVARQASINAGLPIEVPAVTINVVCGSGLNCVNLAATKIL
                     AGEADIVIAGGMENMSLAPFCLDKARFGYRMNNGVLKDCMVNDALTDAFNQYHMGITAE
                     NVAEQWHLTREELDEFSANSQQKATAAIEAGKFKDEIVPVEVKLKKKTVVVDTDEGPRP
                     GTTAESISKLRPAFKKDGIVTAANSSGINDGAACVVVMSEEKAKELGVTPMATWIAGAL
                     GGVDPSIMGVGPVASTKKVLAKTGMSIDDFDLIEANEAFAAQSLAVGRELGINPEKLNV
                     NGGAIALGHPVGASGCRILVTLLHEMQKRDAKKGLATLCIGGGMGCSTIVERD"
     CDS             2424..3209
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: EC1_2-faecali"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_3"
                     /sec_met_domain="EC1_2-faecali (E-value: 5.2e-92, bitscore:
                     297.3, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFIDYEVDGQVGIITINRPKALNALNSEVLKDLDATIDAVDLDA
                     IRCLIITGAGEKSFVAGADIGEMSTLTKAEGEAFGKAGNDVFRKIETLPIPVIAAVNGF
                     ALGGGCEISMSCDIRLCSENAVFGQPEVGLGITPGFGGTQRLARIVGPGKAKQLIYTAR
                     NIKAAEAYRIGLVNEVYPLEELMPQAKKMAKGIAKNAPIAVRACKKAINEGLEVGMDEA
                     IVIEEKLFGSCFETEDQKYGMAFFLDKNKEKVKEPFKNC"
     CDS             3278..4117
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_4"
                     /sec_met_domain="HCDH (E-value: 1.4e-38, bitscore: 121.3,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 6.6e-62, bitscore: 198.3,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGVIGAGTMGSGIAQAFAQTEGYEVYLCDINDEFAANGKKKIA
                     KGFEKRVARGKMDQAKADAILAKITTGTKDICTDADLVVEAALEVMEVKQQTFKELQDI
                     VPATCMFATNTSSLSITQIGAGLDRPVIGMHFFNPAPVMKLIEVIAGLNTPDEMVEKIK
                     AISVEIGKTPVQVEEAAGFVVNRILIPMINEAVGIYADGVASVEGIDTAMKLGANHPMG
                     PLALGDLVGLDICLAIMEVLYNETGDPKYRPHPLLRKMVRGGKLGQKTGIGFYNYSK"
     CDS             4218..5372
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_5"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.5e-52, bitscore:
                     167.5, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.8e-31, bitscore:
                     96.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.5e-41, bitscore:
                     131.3, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFTLSKKHEMARQLFKEFAENEVKPLAQEVDETEHFPEETVAKM
                     QKLGFMGIPVPKEYGGQGCDPLTYIMCVEELSKVCGTTGVIVSAHTSLCADPILTYGTE
                     EQKQKYLVPLAKGEKLGAFGLTEPGAGTDAQGVQTKAVLDGDEWVLNGSKCFITNGSYA
                     DYYIIIAITSVDTDARGRKKKKFSAFIVEKGTPGFTFGTKEKKMGIRGSATYELIFQDC
                     RIPKENLLGPMGKGFAIAMHTLDGGRIGIAAQALGIAEGALDATIAYVKERKQFGRAIA
                     AQQNTQFQLANMATQVEAAKLLVYKAAMAKATQRVYSVEAAKAKLFAAETAMDVTTKCV
                     QLLGGYGYIREYDVERMMRDAKITEIYEGTSEVQRMVISGNLLK"
     CDS             5387..6172
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 163.8;
                     E-value: 1.3e-50)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_6"
                     /sec_met_domain="ETF (E-value: 2.5e-51, bitscore: 163.8,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIVVCVKQVPDTKGGVKFKPDGTLDRAAMLTIMNPDDKAGLEAA
                     LRIKDETGAEVTVVTMGLPKAEEVLREAMAMGADKGILVTDRVLGGADTWATSTTIAGA
                     LRNIDYDLIITGRQAIDGDTAQVGPQIAEHLDLPLISYAQDIKVEGDSVIVQRQYDDRY
                     HVLKAKMPCVITALSELNEPRYMTPGGIFDAYDAEITTWGRKDLKDVDDSNLGLAGSPT
                     QIAKASDKVRKGKGVMMTAETAEEGVEYIMDKLLTKHVI"
     CDS             6162..7229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 167;
                     E-value: 1.3e-51)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_7"
                     /sec_met_domain="ETF (E-value: 2.6e-52, bitscore: 167.0,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 7.3e-39, bitscore:
                     121.5, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSNCKGNVVNRMNLEQYKGVFIYAQQVDNKIDAIALELLGKAND
                     LAADLGTDVTAVLIGSDVKGLVDELAEYGADKVIVVDDPELKEYRTEPYTHALASVINE
                     YKPDILLVGATAIGRDLGPRVSARVATGLTADCTVLEIGEFKARGDKEPRQGQLLMTRP
                     AFGGNTIATIACPNHRPQMATVRPGVMQKKEPVAGAKAEVIEYNPGFTPNDKYVEILDI
                     VKSVTETVDIQAAKILVSGGRGVGSAENFALLDDLAEALGGTVSCSRAVVDNGWKPKDL
                     QVGQTGKTVRPNVYFAIGISGAIQHVAGMEESDIIIAINKDPDAPIFDVADYGIVGDAL
                     KIVPKLTEAIKAQVK"
     CDS             7738..8028
                     /locus_tag="ctg95_8"
                     /transl_table=11
                     /translation="MAQIIASTKEISNKRESLIVLSNSLKNKISLLETLGNSLNSMWEG
                     AAKEKYVKQLKTDISKMRNLLKTILEFILILEKIIAIYNKAEKKNEATAVS"
     CDS             8040..8357
                     /locus_tag="ctg95_9"
                     /transl_table=11
                     /translation="MADLINVTPEKLKATASSFQQAGKDVKKTTSDMLQLVRGISSSIW
                     SGEASSIYLGKFNGLDADIAKMCKMIEEESQHLTTIAQEYQLAEEQNKQVAATLKNNVI
                     A"
     CDS             8382..9098
                     /locus_tag="ctg95_10"
                     /transl_table=11
                     /translation="MLSVMIFCHDKREGDLIGKICNQCVALIDKEFLRNFIISDEEYHQ
                     VNIEGIQPPDLLVVEITGIEDLCRAKRIRGIFPRGRLLVVSTNQISAEYYLIPEVSPDM
                     LLLKPYVYAKACKIIHRSLTWCCKDKCRKKKQEDILKIRTGGEIYYFHYEEIQYLEARD
                     KKIILHVNKYEISFYSSLQKLEKSLPDYFIRCHRSYIVNFMFIQKADLINGEFYLNKKT
                     VIPISQKYKAKLAKML"
     CDS             9207..10547
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AcetylCoA_hyd_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AcetylCoA_hydro"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg95_11"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 4.8e-64,
                     bitscore: 204.6, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 9.4e-31,
                     bitscore: 97.0, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFIKEYAQKLVTAEEAVKVVKSHDWVDYGWTTGTPVALDAALAA
                     RADELEDVKIRGGILLREPEIFKVNNVADHFTWNSWHMGGLERKAISKGFAYYSPLKYS
                     ELPRYYRENIKHLNVAMFQVAPMDKHGFFNFGPNASHMMAVCEAADVIIVEVNENMPRC
                     LGGFEEGIHVSRVDYIVEGENPAIGELGAGAPPTEVDKAVAQLIVEEIPDGACLQLGIG
                     GMPNTVGSMIAESDLKDLGVHTEMYVDAFVDIAKAGKITGLKKNIDRGRQVYAFGAGTK
                     KMYDYLDDNPECMSAPVDYTNSAKTIAQIDNFISINNAVDIDLYGQVNAESAGIKQISG
                     AGGQLDFVQGAYLSKGGKSFICCSSTFTSKDGVKHTRIRPTLAEGSTVTDTRPNTHYVV
                     TEFGKVCLKGMSTWERAEALINIAHPDFRDELIKEAEKMHIWRRSNK"
     CDS             complement(10845..11294)
                     /locus_tag="ctg95_12"
                     /transl_table=11
                     /translation="ENFLVCRTSIPPKKKLNILTRVINNISNKYDGADLKTKMDTKSAL
                     QKEYVDNKSFDIEEIGNKLFGKSPEKKSEFDEKMEQYDLQYDNFTVTNESTVKKLEKQV
                     MVTDSGIEISIPMETYNKLANFEVQTDVTGKSTIIIRNIDNLVLK"
ORIGIN
        1 taagacaccg ccctttcacg gcggtaacat gggttcaaat cccgtaggag tcacttgtgg
       61 cgtcgtagcc aagtggtaag gcagaggtct gcaacacctt catcaccagt tcaaatctgg
      121 tcgacgcctc ttaaaagaga ctaagtgatt agtctctttt tagcatttct ttttaattta
      181 atatcgcggg gtagagcagt ctggtagctc gtcgggctca taacccggag gtcgttggtt
      241 caaatccttc ccccgcaatt tgaggaacat cggtacattg gtatcggtgt ttttttattt
      301 gtttaaactg acgcaatagt aaaacccgct ataagtctat ctgtggcctc ggagcaagtg
      361 ttggatacga gcgtctaagc gaacattcaa cacgccgcga ctaaagtcac agatagactt
      421 atagcgagct ttactattgc tggctttgaa ggaaacaaag taaaaattct tagatgtgca
      481 acgattcgat gttggggaga gtgtgtgaat ttaaaatata gattttttgg tattgatttt
      541 gttaatataa ttacaatgat aaaaacaaat tgcaatacaa aatatacata atttcatcta
      601 cagctatccg ggcaattttc aaatccctcc atatagacat tctaaactaa atccttccaa
      661 cagatagaaa agccagagat actttatgta ccatatgctt tatttcactg tgcaaaatgc
      721 cataaaactc actccaaagc cacatctggc aggtaaagta tctctggttt ttcgtctatt
      781 agccaactca gaatgtctat ttcttcacat atttaggcag ttttttgtat tttgtttcct
      841 tttttcacaa aatcagaaaa ttaatcaata gagaatgtcc atagatataa gaagaaataa
      901 aggtaaaatt aattaaaaca acgatggatt ttgtattcaa aagtgacgaa actgtgaatc
      961 tttcataaat gaaaatatta attaaaaatt tttttataat cttgttgcaa agcaaagaag
     1021 attgtgataa gattaacaca tatcgtacta gaaatgctct agcaaagcaa ctatcaaata
     1081 atattgataa cttaaatgga ggaatgaaac tatggcaaag aaagttgtat tagcaggtgc
     1141 ttgtcgtacc gcaatcggaa caatgggtgg tggattaagc acagtaccag ctgcagattt
     1201 aggaagcatc gtaattaaag aagcgttaaa gagaactaac gtacctgctg atcaggtaga
     1261 cgaagtatta atgggatgtg ttatccaggc tggtcttgga cagaacgttg ctcgtcaggc
     1321 ttctattaat gcaggcttac caatcgaagt acctgctgta acaattaacg tagtttgtgg
     1381 ttccggtctt aactgtgtta accttgctgc tacaaagatt ttagcaggtg aggctgatat
     1441 cgttatcgct ggtggtatgg aaaacatgtc attagctcca ttctgcttag acaaagctcg
     1501 ttttggatac agaatgaaca atggcgtatt aaaagactgt atggttaacg atgcattaac
     1561 agatgctttc aatcagtacc atatgggtat tacagctgaa aacgttgcag aacagtggca
     1621 tttaacaaga gaagagttag atgagttctc cgctaattca cagcagaaag ctacagcagc
     1681 tatcgaagct ggtaagttca aagatgagat tgttcctgta gaagttaaac ttaaaaagaa
     1741 aacagttgtt gtagatacag atgagggacc acgtcctgga acaacagcag aaagtatttc
     1801 taaattacgt cctgctttca agaaagatgg tatcgtaaca gctgccaact cttcaggtat
     1861 taacgatggt gctgcttgtg ttgttgttat gagcgaagaa aaagctaaag aattaggtgt
     1921 aactccaatg gctacatgga tagcaggagc attaggcgga gttgatcctt ctatcatggg
     1981 tgttggacca gttgcttcta ctaagaaagt tcttgcaaaa acaggcatga gcattgatga
     2041 ctttgactta atcgaagcta acgaagcttt cgcagctcag tcattagcag taggaagaga
     2101 attaggaatc aacccagaga agttaaatgt taatggtgga gctattgctc ttggacatcc
     2161 agtaggagca tcaggatgcc gtatcctcgt tacattatta catgagatgc agaaacgtga
     2221 tgctaagaaa ggtcttgcta cactgtgtat cggtggtggt atgggctgct caacaatcgt
     2281 tgaaagagac taatcacgta tagaatgatt acatatatcc gggttcggtt ttcgaatccg
     2341 gttatatcaa ttacatagtt tgtaactatt taattatcta gattgaatag ttagctaatg
     2401 taatctgaaa ggagatacat acaatgggat ttatcgatta tgaagtagat ggccaggttg
     2461 gtattatcac catcaatcgt ccaaaggctt taaatgcttt aaacagtgaa gtattaaaag
     2521 atttagatgc aactattgat gcagtagatt tagacgcaat cagatgtctt atcattactg
     2581 gtgctggaga gaaatctttc gtagcaggtg ctgatatcgg agagatgagt acacttacaa
     2641 aagcagaagg cgaagctttc ggtaaagctg gtaatgatgt attcagaaag attgaaacac
     2701 ttccaatccc tgttatcgca gcagtcaacg gattcgcttt aggcggtggc tgtgagattt
     2761 ctatgagctg tgacatcaga ctttgctctg agaatgcagt gtttggacag ccagaagttg
     2821 gtcttggaat tacacctggt tttggtggaa cacagagact tgctcgtatc gtaggacctg
     2881 gaaaagcaaa acagttaatc tatactgctc gcaatattaa agcagcagaa gcttacagaa
     2941 ttggtctggt taacgaagtt tatccacttg aagagttaat gcctcaggct aagaagatgg
     3001 caaagggtat tgcaaagaac gcacctatcg cagttcgtgc atgtaagaaa gctatcaacg
     3061 aaggtttaga agtaggaatg gatgaagcta tcgtaatcga agagaagtta tttggcagct
     3121 gcttcgagac agaagaccag aaatacggaa tggcattctt ccttgacaaa aacaaagaaa
     3181 aagtaaaaga gccatttaaa aactgctaat taatcaatta tacatattgt attattaatt
     3241 atcggaatac attacatttt ataggaggtt tcagacaatg aaagttggag ttattggcgc
     3301 aggtacaatg ggatcaggta ttgctcaggc attcgcacag acagaaggat acgaagtata
     3361 cttatgtgat attaacgatg aatttgctgc aaacggtaaa aagaaaatcg ctaaaggatt
     3421 tgaaaagaga gtagcaagag gaaaaatgga tcaggctaaa gctgatgcaa tccttgctaa
     3481 aatcactaca ggtacaaaag atatctgtac agatgctgat ttagtagtag aagcagctct
     3541 tgaagttatg gaagttaaac agcagacatt taaagaatta caggatatcg ttcctgcaac
     3601 atgtatgttt gcaacaaata catcttcttt atctattaca cagattggtg caggacttga
     3661 cagaccagtt atcggaatgc atttcttcaa cccagctcca gttatgaaat taattgaagt
     3721 tatcgctggt cttaatacac cagatgaaat ggttgaaaag attaaagcta tctccgtaga
     3781 aatcggcaaa acacctgtac aggtagaaga agctgcagga ttcgtagtta acagaatctt
     3841 aatcccaatg attaacgaag cagttggcat ttatgctgat ggtgttgctt ctgttgaagg
     3901 tatcgacaca gctatgaagt taggtgctaa ccatccaatg ggacctctcg ctttaggaga
     3961 tttagttggt cttgatatct gccttgcaat catggaagta ttatataatg aaacaggaga
     4021 tcctaagtat cgtccacatc cattattaag aaagatggtt cgtggtggaa aattaggtca
     4081 gaagactggt attggattct acaattacag caaataatta aaaaagtgaa tacggccgtg
     4141 gggactatgc tctgcgtctc cacggctttt aaggtggttc tccaccccaa taaccaattt
     4201 attatggagg aatgaaaatg gatttcacat taagcaaaaa gcatgaaatg gctagacagc
     4261 tctttaaaga gttcgctgaa aacgaagtta aacctcttgc tcaggaggtt gacgagacag
     4321 aacattttcc agaagaaacc gttgcaaaaa tgcaaaaatt aggtttcatg ggaattcctg
     4381 tgccaaaaga atatggcgga cagggctgtg atcctttaac atacattatg tgtgttgaag
     4441 agttatctaa agtttgtggt acaacaggtg ttattgtatc cgcacataca tcattgtgtg
     4501 cagatccaat tcttacttac ggtactgaag aacagaaaca gaaatatctt gttccacttg
     4561 caaagggtga aaagttaggt gctttcggtc ttacagagcc aggtgctggt actgacgctc
     4621 agggtgttca gacaaaggct gttttagatg gtgacgaatg ggtattaaac ggatctaaat
     4681 gtttcatcac taacggttct tatgctgatt actatattat catcgctatc acaagtgttg
     4741 atacagatgc aagaggaaga aagaaaaaga aattctccgc atttatcgta gaaaaaggaa
     4801 ctccaggatt tacatttggt acaaaagaaa agaaaatggg tatccgtggt tcagctacat
     4861 atgaattgat tttccaggat tgtcgtattc ctaaagaaaa tcttcttgga cctatgggca
     4921 aaggtttcgc aatcgctatg cacacattag atggtggacg tatcggtatt gcagctcagg
     4981 ctcttggtat cgcagaaggt gctttagatg ctacaattgc ttatgttaaa gaaagaaaac
     5041 agtttggcag agcaattgct gcacagcaga atacacagtt ccagcttgct aatatggcta
     5101 cacaggtaga agctgctaag ttacttgttt ataaagcagc aatggcaaaa gcaacacaga
     5161 gagtatactc cgtagaagct gcaaaagcta aattatttgc agcagaaaca gctatggatg
     5221 taacaactaa gtgtgttcag ttacttggtg gttatggtta catcagagag tacgacgtag
     5281 aacgtatgat gcgtgacgct aagatcacag aaatctacga aggaacatca gaagttcagc
     5341 gtatggttat ttctggtaac ttattgaaat aaggagggaa aatactgtga aaatcgtagt
     5401 atgtgttaaa caggtacctg atacaaaagg tggagttaag tttaaaccag acggaactct
     5461 tgatagagca gctatgctta ctatcatgaa tccagatgat aaggcaggtc ttgaagctgc
     5521 ccttagaata aaagatgaaa caggcgcaga agtaacagta gttactatgg gtcttccaaa
     5581 agcagaagaa gttctgcgtg aagctatggc aatgggtgct gacaagggta tccttgtaac
     5641 agaccgtgtt ttaggtggag ctgatacatg ggcaacatct acaacaatcg ctggagcact
     5701 tagaaatatt gattatgatt taatcatcac aggtcgtcag gctatcgatg gtgatactgc
     5761 tcaggtagga cctcagattg ctgaacactt agatcttcct ttaatttcct atgctcagga
     5821 tatcaaagtt gaaggtgaca gtgtaatcgt tcagagacag tatgacgaca gatatcatgt
     5881 tttaaaagct aaaatgccat gtgttatcac agcactttcc gaattaaatg agccacgtta
     5941 tatgactcca ggcggaatct ttgatgcata tgatgcagaa attactacat ggggaagaaa
     6001 agaccttaaa gatgttgatg acagtaactt aggtcttgca ggttctccaa ctcagatcgc
     6061 aaaggcttct gataaggtac gtaaaggtaa aggtgtcatg atgacagctg aaacagcaga
     6121 agaaggcgtt gagtacatca tggacaaact gttaacaaag catgttatct aattgtaaag
     6181 gaaatgtggt gaatagaatg aatttagaac aatataaagg tgtatttatc tatgctcagc
     6241 aggttgacaa taagattgat gccattgctt tagaattact tggaaaagca aatgaccttg
     6301 ctgcagattt aggaacagac gtaacagcag ttttaatagg ttctgacgta aaaggcttag
     6361 ttgatgaact tgctgaatac ggcgcagata aagttatcgt agttgatgac cctgaattaa
     6421 aagaatacag aacagagcca tatacacatg cactggcatc tgttatcaac gaatacaaac
     6481 cggacattct tctggttgga gcaacagcaa tcggtcgtga cttaggacct cgtgtttctg
     6541 caagagttgc aacaggtctt acagcagact gtactgttct tgaaattggt gaattcaaag
     6601 ctcgtggaga taaagaacct cgtcagggtc agttattaat gactcgtcct gcattcggtg
     6661 gtaacacaat cgctacaatc gcttgtccta accatcgtcc acagatggct acagttcgtc
     6721 ctggtgttat gcagaagaaa gagcctgttg caggtgcaaa ggcagaagtt attgagtaca
     6781 atccaggatt tactccaaat gacaaatatg ttgagattct tgacattgta aaatctgtta
     6841 cagaaacagt tgatatccag gctgctaaga ttcttgtatc tggcggacgt ggagttggct
     6901 ctgctgagaa ctttgcatta ttagacgatt tagcagaggc acttggcgga acagtttcct
     6961 gctcacgtgc agttgtagat aacggatgga aaccaaaaga tttacaggtt ggccagactg
     7021 gtaagacagt tcgtcctaat gtttactttg caattggtat ttccggagct atccagcacg
     7081 tagctggtat ggaagaatct gatatcatca ttgctatcaa taaagaccca gatgcaccta
     7141 tctttgatgt agctgattac ggtattgttg gtgatgcatt aaagattgtt cctaagttaa
     7201 cagaggcaat caaagctcag gttaaataat ttcaaatcat agcagactca ttagattatg
     7261 tgagttactg attgaggatt gaaacttaga ttttttgtgg aagtctagta tatgcattct
     7321 cagatgtttt gtgtattgac gattcattat taaaagaagc atataggaga tttgtgctga
     7381 actctataaa atgtatttat gcagggaatc tttttgaaga ttccctgtta aagtgagata
     7441 gtaggactac agtttataac tgtggtcttt tttactttca ttcagttggc atagcccgct
     7501 acgccgtctt cattcaggaa aaattcccca caaattgtaa cgcacatctt gcaaaagcat
     7561 ttttcaaact cgctctagta aaatacgtca tttttatttt atacataata aaaagtaaac
     7621 ataataaaga agtacttatc acaaaataaa cataatttgt caaaaatagt agaaattaat
     7681 tccaaatatg ttataatact cttgcagcag ttaaccgaga tatgagagga ggcatttatg
     7741 gcacaaatta ttgcttcaac aaaagaaata tctaataaga gagagtcact gatagtattg
     7801 agtaattcct taaagaataa gatttcgctt ttagaaactt tggggaacag tcttaattct
     7861 atgtgggaag gcgctgcaaa agagaagtat gtaaagcaac ttaagacaga catttcaaag
     7921 atgcggaact tacttaagac aattttggaa tttatattga tactagagaa gattattgca
     7981 atctataata aagcggagaa gaagaatgag gcgacagcgg taagctagga gggggattta
     8041 tggcagattt aattaatgta actccagaga agttaaaggc gacagcaagt tctttccaac
     8101 aggcaggaaa ggacgttaag aaaactacct ctgatatgct tcagttagtg aggggaatta
     8161 gtagttccat ctggagtgga gaggcgagta gtatatatct tggtaagttt aatggattgg
     8221 atgccgatat cgccaagatg tgcaagatga tagaggaaga atcacagcat ttgacaacaa
     8281 ttgcacagga ataccagtta gcagaagaac agaataaaca ggttgcggca acattaaaga
     8341 ataatgtaat tgcttagatt gtatagacag atgaatagat tatgctgtca gttatgattt
     8401 tttgtcacga caaaagagaa ggagatttga ttggaaagat atgtaatcag tgtgtagcgc
     8461 ttatagataa agagttttta cgtaatttta tcataagcga tgaagaatat catcaggtga
     8521 atatagaggg aatacagccg ccagatttac ttgtagtaga aatcacaggt atagaggatt
     8581 tatgcagggc gaaacgaata agggggattt tcccaagagg acgattgcta gttgtaagta
     8641 ctaatcagat ttcagcagag tactatttaa ttccggaagt ttcaccggat atgcttttac
     8701 tgaaaccata tgtatatgcg aaagcttgta agattataca ccgaagtctt acatggtgtt
     8761 gtaaggataa gtgtagaaag aaaaagcaag aagatatatt aaagattcgg acaggaggag
     8821 agatttatta ttttcattat gaagagattc agtatttaga agcaagagat aagaagatta
     8881 tcttgcatgt aaataagtat gagatttctt tttatagttc cttgcaaaag ttggagaaga
     8941 gcctgccaga ttattttatt cgttgccatc gtagttatat tgtgaatttt atgtttattc
     9001 aaaaagcaga tttgataaat ggtgaatttt atttgaataa aaagacagtt attccaattt
     9061 ctcagaaata taaggccaaa ttagcaaaaa tgttgtaaaa atataaggat tcaaggttcg
     9121 atttaggttg accgagttat acaacggtgg tagaatatac tcatgatatt tttttaacaa
     9181 gagcagaagt tgttaggagg agaagcatga gtttcattaa agaatatgca cagaaacttg
     9241 ttacagcaga agaagcggtt aaggtagtaa aatctcatga ttgggtagat tatggttgga
     9301 caaccggtac tccagttgca ttggatgcag cattagcagc cagagcagat gaattagaag
     9361 atgttaagat tcgtggtggt atcttattaa gagaaccaga gattttcaag gtaaataatg
     9421 tagcagatca ttttacatgg aattcctggc atatgggtgg tttggagaga aaggcaatca
     9481 gtaaaggatt tgcatactat tctccattaa aatattcaga acttccacgt tattacagag
     9541 agaatatcaa gcatttgaat gttgcgatgt tccaggttgc tccaatggat aaacatggat
     9601 tctttaactt tggaccaaat gcatcccata tgatggcagt ttgtgaagct gcagatgtaa
     9661 ttatcgtaga ggttaatgag aatatgcctc gctgtctggg tggatttgaa gaaggcattc
     9721 atgtttctcg cgtagattac atcgtagaag gcgagaatcc agctattggt gagttaggag
     9781 ctggcgcacc accaacagaa gtagacaaag ccgtagcaca gcttatcgta gaagagattc
     9841 cagatggagc atgtttacag cttggtatcg gtggaatgcc taatacagta ggttccatga
     9901 ttgctgaatc tgatttaaag gacttaggtg tacatacaga gatgtacgtt gatgcgtttg
     9961 ttgacattgc aaaggcagga aagattacag gcttaaagaa gaatatcgac agaggacgtc
    10021 aggtatatgc attcggtgca ggtactaaga agatgtatga ttatctggat gataacccag
    10081 aatgtatgag tgcaccagtt gattatacga atagcgctaa gacaatagca cagattgata
    10141 actttatttc tatcaataat gcagttgata ttgacttata tggtcaggtt aatgcagaga
    10201 gtgcaggtat aaaacagatt agtggtgcag gtggacagct tgatttcgtt cagggtgcat
    10261 acttatctaa gggtggtaag agttttatct gttgttcttc tacatttaca tccaaagatg
    10321 gtgtaaagca tacaagaatc agacctactt tagcagaagg atctacagta acagatactc
    10381 gtcctaatac acattatgtg gtaacagaat ttggtaaggt atgccttaaa ggtatgtcta
    10441 catgggaaag agcagaagca ttaattaata ttgctcatcc agattttaga gatgaattaa
    10501 ttaaagaagc agaaaagatg catatttgga gaagaagtaa caaataatga tcatagcttt
    10561 gaataagata tcatatgtcg ggaaattagc taaaaagtaa aaatttaagg caagatatca
    10621 agaaacctct cacacaaaag ataaacaaac tgcaagtttg agatgatttt gtgtgggagg
    10681 ttttttaatt taataaatat ttacagctag aatgtttttc aaacacgctc tagaatattc
    10741 acaagtaaat aatattaaaa acagtagtgt aataattgtg gaagtatcaa tgtaatattt
    10801 atttagaatc taatatgttt ataaagttta ttctgaatgt aatattactt taaaacaaga
    10861 ttatcaatat ttcttatgat aatcgttgat ttaccagtta catctgtttg aacttcaaag
    10921 ttagccagtt tgttataagt ttccattgga atagatattt caattccgct atcagttacc
    10981 atgacctgct tttctaattt ctttacagta ctttcattgg tgacagtaaa gttatcatat
    11041 tgtaagtcgt actgttccat tttttcatca aattctgatt ttttttctgg actttttccg
    11101 aaaagtttat tacctatttc ttctatatcg aaagatttgt tatcaacgta ttctttttga
    11161 agagcacttt ttgtatccat ctttgttttt aaatcggcac catcgtattt attagaaata
    11221 ttattaataa cacgagtaag aatatttaac ttcttttttg gaggaatact ggtacggcag
    11281 acaagaaagt tttc
//
