GCA_958429005.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaNEMGGLJB_146 (original name was: gnl|Prokka|NEMGGLJB_146)

Region	Type	From	To	Most similar known cluster		Similarity
Region 146.1	NRPS-like,NRPS	1	5,234

gnlProkkaNEMGGLJB_147 (original name was: gnl|Prokka|NEMGGLJB_147)

Region	Type	From	To	Most similar known cluster		Similarity
Region 147.1	cyclic-lactone-autoinducer	1	5,221

gnlProkkaNEMGGLJB_247 (original name was: gnl|Prokka|NEMGGLJB_247)

Region	Type	From	To	Most similar known cluster		Similarity
Region 247.1	RRE-containing	1	4,057

gnlProkkaNEMGGLJB_422 (original name was: gnl|Prokka|NEMGGLJB_422)

Region	Type	From	To	Most similar known cluster		Similarity
Region 422.1	cyclic-lactone-autoinducer	1	3,085

gnlProkkaNEMGGLJB_524 (original name was: gnl|Prokka|NEMGGLJB_524)

Region	Type	From	To	Most similar known cluster		Similarity
Region 524.1	cyclic-lactone-autoinducer	1	2,713

Region	Type	From	To	Similarity
Region 146.1	NRPS-like,NRPS	1	5,234
Region 147.1	cyclic-lactone-autoinducer	1	5,221
Region 247.1	RRE-containing	1	4,057
Region 422.1	cyclic-lactone-autoinducer	1	3,085
Region 524.1	cyclic-lactone-autoinducer	1	2,713

Compact view

gnlProkkaNEMGGLJB_146 - Region 1 - NRPS,NRPS-like

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Location: 1 - 5,234 nt. (total: 5,234 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 5234:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg146_2

Search NORINE for peptide: strict or relaxed

AMP-binding (18..395): Cys

nrpys: Cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Small clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Single AA prediction:: Polar, uncharged (aliphatic with -SH) (Cys)

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNLSLIWK
Nearest Stachelhaus code(s):: Cys DLFNLSLIWK (79% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaNEMGGLJB_147 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 5,221 nt. (total: 5,221 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaNEMGGLJB_247 - Region 1 - RRE-containing

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Location: 1 - 4,057 nt. (total: 4,057 nt) Show pHMM detection rules used

Region on contig edge.

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaNEMGGLJB_422 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 3,085 nt. (total: 3,085 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaNEMGGLJB_524 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 2,713 nt. (total: 2,713 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.