LOCUS       gnlProkkaHCKKLNFN_111  10629 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HCKKLNFN_111.
ACCESSION   gnlProkkaHCKKLNFN_111
VERSION     gnlProkkaHCKKLNFN_111
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 11:19:36
            Original ID  :: gnl|Prokka|HCKKLNFN_111
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10629
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10629
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6509:6776]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6510..6776
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10629
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10629
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             359..685
                     /locus_tag="ctg111_1"
                     /transl_table=11
                     /translation="MKNCYGIDFRSWRKELRTREKTKQTPCKLPDRVSRSLQGVLFKVY
                     QISVLILLKKILFSFFSVCLPLFIRHIAAMLLRKTSSKTMQTVTKYLKELSGVRSDNSP
                     NSYK"
     CDS             complement(825..1001)
                     /locus_tag="ctg111_2"
                     /transl_table=11
                     /translation="MFVYPLFRPSHCPFPGYTTVTHVVCVYTIPLMGENHINIDVSILV
                     VIFREIFKFAKFE"
     CDS             1050..1265
                     /locus_tag="ctg111_3"
                     /transl_table=11
                     /translation="MKQNTPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             1279..4857
                     /locus_tag="ctg111_4"
                     /transl_table=11
                     /translation="MMKLRNLMQVACMATAALTAFSCSQEEFENSGRKGNITVNATFEG
                     AGTDTRTTVNDKYKILWQDTDALGLFCSNAESNYSNTKLEYASGAGQTSATFNGSKPSG
                     ETAVFSIYPYQQNMSVSGNTLTMTLPATLTNYNGSSNGPMYAKVTNPDNLSALSFKHMA
                     AMIKLTVNKIPAEATTFKIIASNNIAGTCTVDLTAADPILTVASNGSKEITASFTASND
                     IKSRNFYIPLPTGTYSSITAQLTNGSDKVYFTKTLNDKILGRRDILVVPPLDCVVVDAT
                     TPSALSTALADSKNLPQEAPTAATVTDIAVSGSFNTTSGSNDGIAIPVLQNSDINLTFN
                     TAPTTSTAAPLTLTDKTNTSVSAPAATATNSVSLAVPETTAEQEAPSVAITMPSTTVTL
                     AAVGNKATYNEVTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGNTTIYI
                     IKGTEASLPATIDSKFVVQSDVAVLKTAFANGEDFKLSADADITGQSVSVPAGKSVVLD
                     LNGYTLTADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGEDAS
                     MTMESGNISAVRETPDSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNSIIN
                     ITDGELISTADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGTGST
                     GNWGDGTGGLDCAAINVSGAYGIATVNIKGGTLIAEAKSLITEGTTYTPVINVTGGTFS
                     DPSALKYMKANANVNIKLTADKTCPGFKTTSGQTLTMDLGGKILTLADPTVGSTGTETN
                     SCQLLEGSNVTFKNGTLKSDNNKIMIQNYCNLTLDNMTVEDTNAQYVVSNNCGNISINN
                     TTINAGSNANQFAFDVCGYAKYTAGVTVTVSGTSVINGKVEISKSAGNTELMKLNITSG
                     TFNGDLKVDASVGTENAQSIISVSGGTFSDPSVLKYMATNATVDIKLLSNINIAKTELA
                     TGYILNAANATANLNLNGHDIINSSETADATPFTQIFTVQNGTLNISGNGNVKCDASAT
                     AKDDGYRMVIEARGYGTVNIHGGSYYNTQKLNTQIDLIYARENGKINIYGGTFESGKYG
                     TPNNDTDGRYWVLNLKNTDKNTASIQVSGGTFINFNPANPNMDDNESYLVTGYEVTRDG
                     SVYTAAHKVGDGRKEYIVGQTSQENR"
     CDS             5104..6030
                     /locus_tag="ctg111_5"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETTTKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVATVTEL
                     ATLAPVYHLKCLPDREATELCRKTVEG"
     CDS             6057..6497
                     /locus_tag="ctg111_6"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVTVLARDLTERIVFHRIIRRNGDILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             6510..6776
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg111_7"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 7.9e-14,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.7e-16, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             6785..7948
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg111_8"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.8e-46, bitscore:
                     148.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRVLYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRYFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRSKGVKDKKARTKK"
     CDS             7971..9641
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 277.6; E-value:
                     3.6e-84)"
                     /gene_kind="transport"
                     /locus_tag="ctg111_9"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHIAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTTAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLSGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVFDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPELELKDVTFRYTPDDRPVFSRFSCRFPAGSCIAIVGETGKGKTTLIRLLLALATPQ
                     EGQILLIPAKHPLETNHTVSPQTRKNFVYVPQGNTLFSGTIRDNLLMGNPQASQEAIYQ
                     ALQTATADFVFHLPDGVDSPLSERGGGLSEGQAQRIAIARALLRPGNILLLDEATSALD
                     PDTERLLIKNLRRDCAGKTCIFVTHHPAVAEACESIVRL"
     CDS             complement(9686..10597)
                     /locus_tag="ctg111_10"
                     /transl_table=11
                     /translation="MKPTLFLLAAGMGSRYGGLKQLDGLGPNGETIMDYSIYDAINAGF
                     GKLVFVIRKDFEQDFRDKIISKYEGHIPCELVFQSIDDLPEGFTCPEGRTKPWGTNHAV
                     MMGADVIKEPFAVINCDDFYGRDSFQVMGKFLAALPEGSKNVYSMVGFRIGNTLSESGT
                     VSRGLCGTDANNLLTSVVERTKIQRMDGEVKYIDDNGEWTATPETTPVSMNFWGFTPDY
                     FAYSAEFFKSFLSDPKNMENLKSEFFIPLMVDKLINDGTATCEVLDTTSKWFGVTYPED
                     RQSVVDKIQALVDAGEYPAKLF"
ORIGIN
        1 catccgtaat agctctggag ttagtgacgc ctaacggcca tgaacaaccc tgcttacggt
       61 cgtcaagcga tcgctttatg gccgaaagca gggttgttca tggccgttag gcgtcataaa
      121 ttccctatgc cacagcagac aaacaaaggg agaagagcaa aggaatacct atgttttaga
      181 taaaaatcca caagctttca ctcgtgctct ccataggtta tgagagcagg cttcgcgctc
      241 tgtgcgataa attcccattt atcagcaggc atactcactt acgaaacttc aattacttat
      301 ataaattgtt tcagccaaag gcagtacgga catttgcaaa aatatggaaa gtcttattat
      361 gaaaaattgc tatggcatcg acttccgttc gtggcgtaag gagctacgta cacgcgagaa
      421 aaccaagcag acaccctgca aactgccgga cagagtaagc cggagtttgc agggtgttct
      481 gtttaaagta tatcaaatct ctgttttaat tttgcttaaa aagattttat tcagcttctt
      541 ttcggtctgt cttcctctct ttattcgcca catagccgct atgctcctca gaaaaacatc
      601 ctcaaagaca atgcagacag ttactaaata tttgaaggag ttatcgggag ttagaagtga
      661 taactctcct aactcctata aatgaaagag acgtgagcct ttcccaaaaa aaatagagaa
      721 acatagatac acttaaacaa aaaacaatta tctttgtcac gaatccgcta tagcgtagtg
      781 ggtttattta catattagta agagcattat tgaaattatc ttctttattc aaacttcgca
      841 aatttgaaaa tttccctgaa gataacaaca aggatgctca cgtctatgtt tatatggttt
      901 tctcccatca gggggatggt atatacacaa acgacgtgag tgactgttgt atatccaggg
      961 aaagggcaat gcgaaggcct gaataaagga tatacaaaca tagttactca cgtttttttt
     1021 attgtttaac ctttaaataa tttgtgtata tgaaacagaa cacaccagac ggtagagaag
     1081 catacatcac tccgtctatc gaagttatca aaatggagaa tgaaggagtc attgcaacaa
     1141 gcggcgaacc ttaccatccc attacgcgct cctattcggg cagcacctct acccatagct
     1201 acaattcggc atccagcagc gacttggaag acctaatcaa tgacatctta accgtagaaa
     1261 actaaggggg acttcattat gatgaaatta agaaacctta tgcaagttgc ctgcatggca
     1321 actgctgcct tgaccgcatt cagttgcagc caagaggaat ttgaaaacag cgggcggaaa
     1381 ggaaacatca ccgttaacgc aacgtttgaa ggcgcaggta ccgacacccg tactaccgta
     1441 aacgataaat acaagattct atggcaagat accgatgccc tagggttgtt ctgtagtaat
     1501 gcagaaagta attatagcaa tacaaaatta gaatatgcaa gcggtgctgg tcaaacttcc
     1561 gccactttca acggcagcaa gccaagcgga gaaacggctg tattctccat ctatccttac
     1621 caacaaaaca tgagcgtaag cggcaataca ttgaccatga ctctacctgc cacgcttaca
     1681 aattataacg gcagcagcaa tggcccgatg tatgccaagg tgacaaatcc cgacaatctg
     1741 agcgctctgt ccttcaagca catggcagcc atgataaaac tgaccgtcaa caagattccg
     1801 gcagaggcca ctactttcaa gattattgcc tccaataaca ttgcaggtac ttgtacggta
     1861 gacttaaccg cagcagaccc gatactgacg gtagcaagca atggaagcaa ggaaatcact
     1921 gcctccttca ctgcttcaaa cgatataaaa tcgcgcaact tctacattcc tttgcccaca
     1981 ggtacttata gttccatcac tgcccaactg acgaatggaa gcgacaaggt atattttacc
     2041 aagacgctta atgacaaaat cttagggaga agagacatat tggtagtacc tcctttggat
     2101 tgcgttgttg tagatgctac aacccccagt gcgcttagta cagctttagc tgattcaaaa
     2161 aatctcccac aagaagcacc gacagcagca accgtaaccg acattgcagt cagcggcagc
     2221 ttcaatacca cttctggcag caacgacggc atcgccatcc cggttttaca gaactcggac
     2281 atcaacctga cgttcaatac agccccaacg accagtactg ccgctccgtt gacgctgacc
     2341 gacaagacca ataccagcgt aagtgctccc gccgccactg ccaccaacag tgtatccttg
     2401 gctgtaccgg aaaccacagc agagcaagaa gctccttctg tagccatcac catgccaagc
     2461 accaccgtta cattggcagc agtaggcaat aaagccactt acaatgaagt gactgccact
     2521 accgcccagc agacattgat tatcaatgca ggcgtcaccg taaagaagct gactgtaaaa
     2581 ggcggtaact tgaagatata tggaaaggta gaacaattgg tacacgatgc cggcaatacc
     2641 acaatctata taataaaagg aactgaagca tcacttccgg caacaatcga cagcaaattt
     2701 gtagttcaat ccgacgtggc agtcctaaag accgctttcg ccaacggcga agattttaaa
     2761 ttgtccgccg atgccgacat cacagggcaa agcgtcagtg tacccgccgg aaagtccgtg
     2821 gttcttgact tgaacggata tacactgact gccgacaaca gcgcaacagg caaaatcatc
     2881 gtcttgggca agatgacact gaaggacagc tctaccgaga agaaaggcaa gatagttgcc
     2941 agccaggatt atacagcggc ttcttataat ggcagtctga ttgaaatagc cggtgaagat
     3001 gcctccatga ccatggaaag cggcaacatc agtgcagtca gagagactcc ggacagtaac
     3061 ggccaatatg gcgtcggagt gacggacggt ggagacttca ccatgacagg cggcaagata
     3121 gaagccggat ggtttgcagt ggcaggcaac ggcaattaca agacgcagaa ctccatcatc
     3181 aacatcacag acggagaact catttctact gctgactatg cagtctatct gccccaatcc
     3241 ggcacaacga ccatcagtgg cggcaaggtt tatggtgccg caggaggtgt atgcatccaa
     3301 cgaggcactc tgaatgtgga aggtacagcc ttgattacca gtaaaggcac aggtagcacc
     3361 ggcaactggg gcgacggtac cggaggactg gactgcgccg ccatcaacgt aagtggagca
     3421 tatggcattg ccacagtaaa catcaaaggc ggtacactga ttgccgaagc aaagtcactc
     3481 atcacagaag gcaccactta tacaccggtc atcaacgtta ccggcggtac attctccgac
     3541 ccaagcgcgc tgaagtacat gaaggcaaat gcaaatgtga acataaagtt gaccgccgac
     3601 aagacctgcc cgggattcaa gaccacaagc ggacaaacct tgacgatgga cttaggcggc
     3661 aagattctta cacttgctga cccgaccgta ggttccaccg gcaccgaaac gaacagctgt
     3721 caattactcg aaggttcaaa cgttactttc aagaacggaa cgctgaagag tgacaacaac
     3781 aaaatcatga ttcagaacta ctgcaacctg acattagata atatgacagt agaagacaca
     3841 aatgcccaat acgtagtaag caacaattgt ggcaacataa gcatcaacaa taccactatc
     3901 aacgcaggaa gcaatgcgaa tcaatttgca ttcgacgtat gcggctatgc aaagtacact
     3961 gctggagtca cggttacggt aagcggtacg agcgtcatca atggaaaagt ggaaatttcc
     4021 aagagtgcag gaaataccga acttatgaag ctgaatatca caagcggtac tttcaacggt
     4081 gacttaaagg tagatgcatc cgtgggaacc gaaaatgccc aaagtatcat ctctgtttcc
     4141 ggcggtacat tctccgaccc aagcgtactg aagtacatgg caaccaacgc aactgtggat
     4201 ataaaacttc tctcaaatat caacatcgcc aagacggagc ttgccacagg ctacatattg
     4261 aatgctgcaa acgcaacggc aaacttaaac ctgaatggcc acgacatcat caattcctca
     4321 gaaacagctg atgccactcc tttcacacaa atctttactg tacagaacgg aacactaaac
     4381 atttcaggca acggcaatgt gaagtgcgat gcatctgcta cagcgaaaga cgatggttat
     4441 cgcatggtaa ttgaagcccg aggatacggg acagtaaata ttcatggcgg ttcttactat
     4501 aacacccaga aactgaacac ccagatagac ctgatttatg caagagagaa tgggaaaatc
     4561 aatatctatg gaggaacatt tgaatccggc aaatatggta cacccaacaa cgacacggat
     4621 ggcagatact gggtactgaa cttaaagaat acagacaaga acactgccag catccaggtg
     4681 tccggtggaa cgttcatcaa tttcaacccg gcaaatccga atatggacga caatgagtcc
     4741 tatttggtaa caggctacga ggttacccgt gacggcagtg tatatacagc agcccacaaa
     4801 gtcggtgatg ggaggaaaga atatattgtt ggccaaacaa gtcaggagaa ccgataagcc
     4861 aaattctaag aaaggaagca atatatcctc gcaaaccaaa cgaagagata tcggaatcgc
     4921 cttattacta tcttttagat gcggcggaca gcggattttc ttttatagat ctgcgtcctc
     4981 cgcgtctaaa gaatgacaac aagacagttg aaaaatctct caaatcttcc tcattcacac
     5041 aaacattcat tatttttctg agtagcccaa agtatcatga ataacaacta acaatcaaaa
     5101 catatgagaa tacagatatt ggattatcaa gtaggaccgc acacctttcg catggtgaaa
     5161 ccttccgact tcaatatatt caaggcgctg ccttcactga ttccgttcat cacgacaata
     5221 gacacgactc aaaaagtaat ctttgaaaca gagatagacg atgacgaaac aacgacaaaa
     5281 cgaaccatag cgaaaactcc cgatgatata tgtttcaact gggaagatgc cgattgcatc
     5341 attcgccctt tgccccacag ctcacacctt gtatccatca ccccacggaa aagcgggaaa
     5401 aactattgga tggagtgcaa cgataacttc aggcaatgct tcatccacct accggcctgc
     5461 aggacagaaa caccggctcc ggaaaacgaa acgaacttcg tactgaacaa cttcttgatg
     5521 atgctctatg ccttcaatgc cgcccgccac catacactgc tgatgcatgc ctcggttgtc
     5581 gctactgaaa caggcaaagg ctacctcttc ttagggaaaa gcggcacggg caaaagtacg
     5641 cacaccgggc tctggctgca acagttctcg gactgccatc tactgaacga tgacaatccg
     5701 atagtacatg tggacagcct cggcaagcaa gccactgttt tcggttctcc gtggagcgga
     5761 aagacacctt gctatcggaa agaatccatg accgtaggcg ccttcgtccg cttggaacaa
     5821 gcaccgcaga atgaaataga gcaagagaga gcagcacatg ctttcgccac cctcctcccc
     5881 tcctgctctt gcctgaagca gaacaaggaa atctataacg ccattgtcgc cactgtgacg
     5941 gaacttgcca cgctggcacc cgtctatcat ctgaaatgcc tgcccgaccg tgaagcgacg
     6001 gaactttgca gaaagacggt agaaggataa gttatgaatg atgaactgaa cagccgatga
     6061 agaaaagcat tcccaacgag atattgcttc ccgaagtggc gcgtctcatc aaagagggac
     6121 atacagtaac catcaccgtg cggggcaaca gcatgaatcc tttcttagtg gaccgccgtg
     6181 accgggtgac actgggcgat ttcaccacag aacagctgca accgggcgtc accgtactgg
     6241 cacgcgacct gacggaacgc atcgtctttc accgcatcat ccgtcggaac ggagacatac
     6301 tcatcctgca aggcgacggc aacctcgccc agaccgaaga aaccgacatc ggacgggtaa
     6361 tgggcgtcat gaccgaagcc atgcgaaaag acaaacggta caccgccgac ggcaaagtct
     6421 ggaagctcta ctcctactgg tggatgaagc taaaccccgc tcgccgctgg ctgctcgccc
     6481 tgttcagaag aatataaaac aaaataacca tgaaaatcaa acaaggattt atcctgcacc
     6541 ggataggcga tgactacatc atcatgcaag acggctcgtc gaacgtggac ttcagcaaag
     6601 tcatcagcct gaaccaaact tccgccatgc tttggcaaga gatagaaaac aaagagttcg
     6661 atacagacag cgtgacagaa gccctgacca gccgctatga tgtagataac gaatcggccc
     6721 gtcgcgatgc gcagaagttt atcgactccc tcgaccgcga aggaatcata gaataaggac
     6781 ggatatgcaa cacgctttct tttcattggt acgctccggc ctgtggggca ctccggcaga
     6841 ccgacaactc ttccggtcgg tctcgccgga cgactgggaa accgtgtacc gcatggcaaa
     6901 ctcacaagcc ctgcttgcac tgacttttga cggcataagc agtctgccgg ccgaactgcg
     6961 ccctccacgc gtcctctatc tgaaatgggc tgcccggact gcacagatag aacaagccaa
     7021 caaacgcctc aaccagcttc tgcccgaact caataccctt taccgggaag ccgggctgca
     7081 tcccgtactg ctgaaagggc aaggcatcgg caccaactac cgcactccct tgcaccggca
     7141 atgcggagac atcgacatct atttaggaaa acaagggcaa cccatagcca accgcctcct
     7201 gctgcaacaa ggcgccatag tcgagggaga agcgtccgac aagcatgcta gctacagttt
     7261 gaaaggagta cacatcgaga accaccgcat catcctccgg ctgaacagtc cgcttgccaa
     7321 ccggtacttt cagcagatta tcagaaaatg gtacccgcag gaaacagact atgccctatt
     7381 ctccgaaacc gggaaagagg actcgaaggc cgtcagtatc gccatacctc cggccacctt
     7441 caatgcactt tatatcttcc tgcatgcctt tgtacatttc ctgaacagcg gaatcggcct
     7501 gcgccagcta tgcgactgga cttgtctgct tgccaatcgc cacaaagaaa tagatgccac
     7561 caccctgctt cgccagttgc aggacctcgg actattgcat gccgcacaag cattcggcta
     7621 cattgccgtc acccgactgg gattgcccgc taaccggctt cctttcccct tggaaggcac
     7681 caagcagata ggagaacaat tattggaaga catcctgtct accggtaact tcgggcaaca
     7741 tgataaccgc atcaagccac gccccaaagg atattgggca ggaaagtggt acaccttctg
     7801 ccgcgccacc cgacgctgca acgaactgcg tcaatttgca ccgtacgaag cactctggta
     7861 tcccgtgact ctgatagggg gaacgatagc tatacaaata aaccgatcaa aaggagtaaa
     7921 agacaagaaa gcaaggacaa agaaataaaa gaacccggaa aataaaagga atgaaaaagc
     7981 aacagaagga caaaaaagtg aaaaaggaca gacgtgaaaa acttaggtat attcgagagg
     8041 tatctgccga acaacgcgga cgtatcctgc taagttgcct caccggcatt ctgggcgtgg
     8101 cctttgccct agcctttatc tatgcaacca aacgggtgat agacaccgct accggaataa
     8161 cagacgacaa cctgacgcat atcgccgttc tcaccgttgt cctgctgact gcccaattac
     8221 tgtgcggagc tgctgacact tggataagta cccgtatgca gatagagacg ggcaacgccc
     8281 ttcgccaccg cctcttctcg cgcttactgc aaagccgctg gaacgaattg gagcgtttcc
     8341 ataccggaga cgtagtgaac cgggtagaac aagacaccac cgccatcgtc acattgctca
     8401 cctcttctgt cccggcattc atcgtcacga gtatacaact gctggcagcc tttctattct
     8461 tctacttttt agacccttca ctgccatggc tgattgttgc catcctgccc gtctttctat
     8521 caggcagccg tttctatatg cgacgaatga aacgctatac acatgatatt cggaacagtg
     8581 acggtcgcat ccagtccgtc atacaagaga gcctgcaaca tcgcatagtg attaaaacat
     8641 tggaacaagg cgaacggcat ctggacaaac tcgatgactt gcaagacatg ctccacagcc
     8701 aagtcatggg acgtacccgt ttctcgcttt ctgcccacat gttagtggcc cttgcctttt
     8761 ccggcggata cctcacggct tttctttggg gagccgttca cctcagcgca ggctgtatca
     8821 ccttcggaac gatgaccgcc tttttgcaat tggtaggaaa agtccagcgt cccgtgttcg
     8881 acctctcacg cctgatacct tccgtagtca atgcccttac cgccatagac cggctattgg
     8941 aattggaaag actgccggca gaagcggatg gtgacagcat attcctcgcc tctaccccgg
     9001 aactggaact gaaagacgtg acttttcgct acactcccga tgaccgtccg gtattcagcc
     9061 gcttctcctg ccgtttcccc gccggtagct gcatagctat agtcggagaa acaggaaaag
     9121 gaaagacaac gctcatccgg ctattgttgg cactggcaac gccacaagag ggacagatac
     9181 tcttgatacc cgccaaacat ccacttgaaa ccaatcatac cgtctctccg caaacccgca
     9241 agaacttcgt atatgtcccg caaggcaata cccttttcag cggaactatc cgtgacaacc
     9301 tgctgatggg aaacccacaa gcttctcaag aagccatata tcaagccctg caaaccgcca
     9361 ccgccgactt cgtcttccac cttcccgacg gcgtagactc cccactcagc gaacgaggtg
     9421 gtggactcag tgaaggacaa gcccaacgca tcgccattgc ccgcgctctg ctacgccccg
     9481 gaaacattct tcttttagat gaagccactt ctgccctcga ccccgacacg gaacggctgt
     9541 taataaaaaa cctgcgcaga gactgcgcag gcaaaacatg tatcttcgtc acccaccatc
     9601 cggcagtagc ggaggcatgc gaatctattg tccgattata atcagagaat aagccccaac
     9661 gggtatctgc ctttggttaa caaactcaga acagcttcgc aggatactcg cccgcatcca
     9721 ccaaagcctg aatcttgtcg actacactct gacggtcttc gggataagtc acaccgaacc
     9781 acttgctggt tgtatcaagc acttcgcagg tagcagtgcc atcgttaatc agcttatcca
     9841 ccatcagcgg gatgaagaat tcgcttttca ggttctccat attcttcggg tcgctcaaga
     9901 aactcttgaa aaactctgca ctgtaagcaa aataatcggg agtgaaaccc cagaagttca
     9961 tgctgaccgg agtcgtctcg ggagtggcag tccattcacc gttatcgtcg atgtacttca
    10021 cctcaccgtc catgcgctga atcttggtac gttccactac ggaagtcagc aggttgttcg
    10081 catccgttcc acacaatcca cgggatacgg taccgctctc gctcaacgta ttgccgatgc
    10141 ggaagcctac catggaatat acgtttttgg agccttcggg aagggctgca aggaatttgc
    10201 ccattacctg gaaggagtca cgaccgtaga aatcgtcgca attgataaca gcaaacggtt
    10261 cctttattac atcggcaccc atcattacag catggttggt tccccaaggt ttggtacggc
    10321 cttcggggca ggtgaagcct tcaggaaggt catctatgga ctggaatacc agttcgcagg
    10381 gaatatggcc ttcgtatttg gaaataatct tgtcgcggaa gtcctgttca aaatctttac
    10441 ggattacgaa aacgagcttg ccaaaaccgg cattgatggc atcgtaaata gaataatcca
    10501 tgatagtttc gccattcggt cccaatccgt ccaattgttt caagccacca taacggctgc
    10561 ccataccggc tgccaataag aataaagttg gtttcatatt agttattatt taaaaaggtt
    10621 agtgtatca
//
