LOCUS       gnlProkkaADEGHPLP_277   5030 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ADEGHPLP_277.
ACCESSION   gnlProkkaADEGHPLP_277
VERSION     gnlProkkaADEGHPLP_277
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 05:53:29
            Original ID  :: gnl|Prokka|ADEGHPLP_277
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5030
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5030
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4535:4886]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4536..4886
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..5030
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5030
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..1106
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 312; E-value:
                     1.2e-94)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg277_1"
                     /transl_table=11
                     /translation="MGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGA
                     FTGAIGERKGYFGEADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVR
                     VVAATNVNLTQAIAEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYR
                     MPAIQLTEDAKKELLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRL
                     PALMGTRESKGFESEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVT
                     TPVVTAHQPSVPAIIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHH
                     GKRKSAAKDLNISERTLYRKIKEYELD"
     CDS             1093..1620
                     /locus_tag="ctg277_2"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             1626..2399
                     /locus_tag="ctg277_3"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQSAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             2406..2801
                     /locus_tag="ctg277_4"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             3050..4438
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg277_5"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             4536..4886
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg277_6"
                     /sec_met_domain="PqqD_RRE (E-value: 1.4e-11, bitscore:
                     32.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.1e-18, bitscore: 54.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQYEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
ORIGIN
        1 gagtcggaaa agaaagtttt ccgcagatta ttcatcaata tagccggagg aagcacggac
       61 agtatattgc tgtcaactgt ggcgctattc cggaaggtac gattgattcc gaactgttcg
      121 gacatgagaa aggtgcgttt accggtgcga ttggcgaacg gaaagggtac tttggcgaag
      181 ctgacggtgg tactattttt cttgatgaag taggggagtt gccgatgtct acccaggcac
      241 gtttgctccg tgtactggag agtggcgagt ttatgaaagt aggttcgtcc aaagtacaaa
      301 aaacggatgt gcgtgtggtg gcggctacca acgtcaatct tacacaagcg attgcagaag
      361 gacgtttccg tgaagattta tattaccggt tgaatacggt gcctatccag ataccgcctt
      421 tgcgtgaacg tggtgacgat gtacttttgt tgtttcgtaa gttttccgca gactttgcag
      481 agaaataccg gatgcccgct attcagttga cggaggatgc gaagaaagag ttgttggctt
      541 acccgtggcc cggaaacgtg cgtcagttga agaacatcac cgagcaaata tctatcattg
      601 aaaccaatag ggagatctct gctgctatct tgcagaatta tcttcctgca caaaatacgc
      661 aacgtcttcc cgcgttgatg ggaacgcgtg agagtaaagg ctttgagagc gaacgggaga
      721 ttctttattc tgttctgttc gatatgcgcc aggaagtggc ggagctgaag aagatggtgc
      781 acaacctgat ggcggaacgt gccggacagg tggggcaggt aggacaaatg ggaacggtgg
      841 ttactactcc ggtagtgacg gcgcatcaac cttcggtacc tgctatcatt cacaccatgc
      901 agcctacggt ttgcaaggat gatgatgaca tacaagacac ggaagaatat gtagaagaat
      961 cccctttgtc actggacgaa gtggagaaag aaatgatacg caaggcactt gagaggcatc
     1021 atggaaagcg gaagagtgcg gccaaggact tgaatatttc cgagcgtaca ctttatagaa
     1081 aaataaaaga atatgaattg gattaagaaa ataatacgcc ctttgttact gttcggcttg
     1141 ccgttggtag tcattgcgtg cactgtttcc tataagttta acggatcgtc tatcaattat
     1201 gataaggtaa agaccatttc gatagccgac ttcccgatca agtcggagta tgtatatgct
     1261 ccgttagcaa ccaaattcaa tgaggacctg aaagatatct tcatccggca gacccgtctg
     1321 caactgctca agccgaatca gaatgcggac ttgcagattg acggagaaat cacaggatac
     1381 aatcagtaca accaggcagt atctgccgac ggttactctt cggagacgaa gttgactatt
     1441 accgtcaatg tacgttttgt caacaacacc aatcatgccg aagactttga acaacagttt
     1501 tctgcgttcc gtacctacga ctctagccag ttgctgactg ccgtacagga cggattgatt
     1561 gctgaaatgt ctaaagagat caccgaccaa atttttaatg caactgtagc aaactggtaa
     1621 tataaatgac ttctgttaac tttcaacaat ggattcagca tcccgagacg ctgaataggg
     1681 atactttgta cgaactgcgc aatcttcttg cgaggtatcc gtattttcag tcacttcgtc
     1741 tgctgtatct gaagaatctg tatattctcc atgatattag tttcggtgga gaactgcgga
     1801 aagcagttct ttacattgca gacagacggc agttgttccg gttgattgaa ggtgaccgct
     1861 atgatgtgca ggcacggaaa aagggagtac ctctcacgga ggtgctgaaa gacgaaccgt
     1921 ccgtagaccg cacattagca ttgatcgacg ctttcttgtc tacagtaccc gaagaggtga
     1981 ctgcccgcac cagcttcgac tattcgatgg attacacctc ttatcttttg gaggagactc
     2041 cggccacgga acagtcggcc gaagaaacgc ccaaactcaa aggctacgaa ctgattgacg
     2101 actttataga aaagagcgag agcgactctc ccctctgcaa gaaaccttta agagaagaaa
     2161 tgccatcttc gccaacctct tcggacgaac ttaccgaaga agaaacaatg aaggaagaag
     2221 aggaagatga cagctgtttt acggaaactt tggcaaaaat ctatgttaaa cagcaacgat
     2281 attcaaaagc tcttgaaata attaaaaaat taagcttgaa atatccaaaa aaaaatgctt
     2341 actttgcaga ccaaatcaga tttttggaga aattgattat taacgctaat tcaaaataac
     2401 taaaaatgta cttattattc gttatcttaa tggttattgc agccttgttg atgtgtttca
     2461 tcgtgctgat tcagaactca aaaggaggcg gacttgcttc tggtttctct tcatctaacg
     2521 ccatcatggg cgtgcgcaag actacagatt ttctggaaaa agcaacatgg ggcttagcta
     2581 tcttcatggt ggtaatgagc attgctactg cttatgtagt tcctcgctct gctgttgcta
     2641 aagacgcagt gttggaacag gcacagaaag aacaacagac taacccgtat aacttacccg
     2701 caggtacggc tgcgccgcaa actgaagctc ctgctaccaa tgcacctgct acagaaactc
     2761 cggcaccggc tactgaaact cctgctcctg cagcagagta attcactccg ttgtcaggta
     2821 agactttggg gtaaaaccat taatgggaag gtgcagacgg atgctgcatt tctttgatat
     2881 ttaagtgcgg attacgcaga ttacacggat tttcaatctt ccgcgtggtc agtgtaatcc
     2941 gcacttaact ttttcttgta aaaacaatct ctttttgata gaaacaaacg agatttaact
     3001 acctttgttg gtcgtatgaa gattattaac tactttttta aatataacaa tgacagaaca
     3061 tttgaaacag aaattgaatg actccgccgt actccgatgg agtgttctag cattggtcgc
     3121 atttactatg ctatgcggct atttcctcac cgacgtaatg tctcctctaa aacccatgct
     3181 tgagaaagaa ctactatggg acagtcttga ttatggtttc ttcacaagcg cttacgggtg
     3241 gtttaatgta ttcctgttga tgctgatttt cggtggtatc attttggata agatgggagt
     3301 tcgtttcacc ggaatggggg cttgcttatt gatggtgttt ggttgtggat tgaaatacta
     3361 tgcgatttct actacttttc cggaaggtgc catgctcttc ggattcaaaa cacaggtgac
     3421 gttggctgca ttgggatatg ctatctttgg tgtaggtgtg gagattgctg gtatcactgt
     3481 ttccaagatt atagtgaaat ggttcaaggg caaggaaatg gcattggcta tgggacttga
     3541 aatggctacg gcacgtatcg gaacaactct ggcaatggtg ctcacggttc ctttggccga
     3601 cttcttcgga tctacggatg agagtggcac attccatacc aatattcctg ctccgatttt
     3661 gttttgtctg attatgttgt gcgtgggtac gattgctttt ttcctttata ctttctatga
     3721 taagaagttg gatgcttctt tggatgcaga gggattggaa ccggaagaac cgttccgtat
     3781 gaaagatatt gtgtatatca ttacgaataa gggattctgg ttgattgcat tactatgtgt
     3841 attgttctac tcggctgtat tcccctttat caagtatgct gccgacttga tggtgcagaa
     3901 gtataatgta gatccgaagt tggcgggaac gattcccgga ttgttgccga ttggtgcgat
     3961 tatcctgact ccgttgttcg gctcgcttta tgaccgtatc ggtaagggag ctacgttgat
     4021 gataatcgga tcagtgatgc ttatttttgt gcatacgatg ttcgctctgc ctatactgaa
     4081 tatatggtgg tttgctacta tcatcatgat tatattggga tttgccttct cgttggtgcc
     4141 ttcagctatg tggccgtctg ttccgaagat tattccggaa aaacagttgg gtaccgcata
     4201 cgcattgatt ttctgggtac agaactgggg attgatgggt gttcctttgt tgatcggatg
     4261 ggtgttgaat acttattgca aaggtccggt agtagacggt gcacagactt atgactacac
     4321 gttgccgatg gctatttttg ctctctttgg tgtgcttgct ctgattgtgg ctttgatgtt
     4381 aaaggcagag aacaagaaga agggatacgg tctggaagag gcgaatatcc aaaagtaact
     4441 gggaaattca atacctaaag taacaaagga attttgtatc aaggtgtaaa caaaagggta
     4501 tcagtatgaa tactctgaaa taaaaaataa gaagtatggc tgccaaagag aaaatcaacc
     4561 tgttagaggt cattccctgt cgcagtgaac atattacagc agaaagggaa ggggagacaa
     4621 ttgtgctctc ctttccccgt tttaaatatc cgtggatgca acgcttcctt gtgccgaaag
     4681 gaatgtcgaa agaacttcat gtgaaattgg aagaacacgg tacggctgta tgggaactga
     4741 tagatggaaa acgcaatgtt cgtgagatta tagaaaaact cgcagaccac tttcaatatg
     4801 aagagggcta cgagtcgcgt gtatcggctt atctttctca aatgcagaaa gatggattta
     4861 taaaactggt gataccagtc gcataaatag gaatttatat ttcaccacag aggacacgga
     4921 ggacacagag gtttaatctt ttttattcac tatagagtaa cacagagtct cacgtattga
     4981 gaatcgtatt tatcgctctg ttttacttgc ggaaagagag agaagaactc
//
