LOCUS       gnlProkkaONJOAAGF_189   4935 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ONJOAAGF_189.
ACCESSION   gnlProkkaONJOAAGF_189
VERSION     gnlProkkaONJOAAGF_189
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 08:06:17
            Original ID  :: gnl|Prokka|ONJOAAGF_189
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4935
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4935
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2628:3993]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2629..3993
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..4935
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4935
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(2..682)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179:hydrolase (Score: 106.8; E-value: 2.3e-32)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg189_1"
                     /transl_table=11
                     /translation="MEQEKKQPDVRLIGLDLDGTTLTSDKVLTPHTKEVLEKCLAEGIQ
                     VLPATGRVKSGIPEYLTQIEGMRYVILSNGASVLDLKEDKVLYQNCIPWERALELFDVL
                     ETYDTFYDIYALGAGWCEARFYDNVENYGIEKHIEKLVRTSRNRIDDLREWMKENKAPV
                     EKINMFFAKEEDRQRAFRELGQIEDLAVTCSLGNNLEINGATCNKGDAMLNLGKILDIP
                     IESIM"
     CDS             complement(853..2628)
                     /locus_tag="ctg189_2"
                     /transl_table=11
                     /translation="MEKWFIASKRADFNKIGEIFHISPVTARLMRNRSLTTVREMQRYL
                     YGSLSDLYDSHLLKDADKGAEIIKEKIETGKKIRIISDYDVDGVSSNYILYQGLKRCGA
                     DVDYKIPDRVEDGYGINEHLIEKAAEDGIDTIITCDNGIAAAEQIAYGNSLGLTLIVTD
                     HHDIPFQRQEDGSISYNLPSAAAVINPKQKDCPYPFENICGAVVVYKFIQVLYDLFGID
                     RRESEVFLEIAAMATVCDVMPLCDENRIIVKEGLRRIQHTNITGLQALIEANHLEEKKI
                     SSYHFGFILGPCINASGRLTSAKDALELLLCEDKELCRQKAEALTQLNAERKEMTANGV
                     KAAKEYLESTGHANDKVLVVYLPNCHESIAGIIAGRMKEHYHKPVFVITRTKEGLKGSG
                     RSIEAYHMYKEMNKIKECFDKFGGHPMAAGFSMQEDRLEEFREKLNANATLTEDDFAEK
                     VHIDVALPISYLSESLINEFELLEPFGNENTKPLFAQKDLYIKGMRVLGTTGRCLKLFL
                     SDANGTSIDAMYFGESDVFLEELISFCGKEEAQRIQKGLSHHIWMDVTYYPQVNEWRGQ
                     KNIQIVIQNYRFKNL"
     CDS             complement(2629..3993)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg189_3"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 4.4e-34,
                     bitscore: 104.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1e-16, bitscore: 49.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 8.6e-15, bitscore: 43.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.6e-21, bitscore:
                     63.3, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKNNGYNIVMDVCSGAIHVVDDVTYDVIALYEEKSLEEIEN
                     ELSYSKEDIEEAYKEVTSLKEEGLLFTEDIYEDYIKEVKSRKTVVKALCLHIAHDCNLA
                     CRYCFAEEGEYKGHRELMSAKVGKAALDFLVANSGNRHNLEVDFFGGEPTMNFGVVKEV
                     VEYGRSLEEKHNKHFRFTLTTNGVLLNDEIMEFANKEMDNVVLSVDGRKEIHDYMRPTR
                     NGKPSYDLIMPKFIRFAESRHQQKYYVRGTFTNRNLDFSKDVLHLADLGFEQISMEPVV
                     GQPEEPYAIQEKDLPQIFDEYDRLAKEMIKREKAGKGFNFFHFMIDLTGGPCVAKRLSG
                     CGSGTEYLAVTPWGDLYPCHQFVGEEKFLLGNVFDGIKRTDICDEFRSCNVYTKKKCKD
                     CFARFYCSGGCPANSYNFHGTIDDSYDLSCDMERKRVECAIMIKAALADTEGEEE"
     CDS             complement(4500..4880)
                     /locus_tag="ctg189_4"
                     /transl_table=11
                     /translation="MDGISYKKWMERAAGLFLSALIAVLLTMLFLAVFAFAMLKGNLSA
                     SVEKIGLIVMSVMACFVGGFLCGKKNMKKRYLWGLGVGVLYCLFFGVIRVGMGQAFVTD
                     TTAFFTMMLYCAAGGMLGGMLS"
ORIGIN
        1 ccataatact ttctatcgga atatcaagaa tttttccaag attgagcatc gcatctcctt
       61 tattacaagt tgccccatta atctcaagat tattaccaag agaacaggta accgccaaat
      121 cttctatctg tccaagttca cggaaagctc tctgtctgtc ttcttccttt gcaaagaaca
      181 tatttatctt ctccactgga gctttatttt ctttcatcca ctctcttaaa tcatcaatac
      241 gattgcgtga tgtacgaacc agcttctcga tatgtttctc aattccatag ttttctacat
      301 tatcataaaa gcgagcctca caccagccag ctcctaatgc ataaatatca taaaatgtat
      361 catatgtttc taacacatcg aataactcca atgctctctc ccacggaata caattctgat
      421 aaagaacttt atcctctttt aaatctaata cacttgcacc attggataaa ataacatatc
      481 tcattccttc aatctgtgtt aaatactctg gaatacccga ttttactctt cctgttgccg
      541 gtaaaacctg aatcccttcc gcaagacatt tctcaagtac ttcctttgta tgtggagtta
      601 acaccttatc tgaagtgagc gttgttccat ctaaatctaa tcctatcaat ctgacatctg
      661 gctgtttttt ctcctgttcc atattttctc cttatctatc tcttaattca tagcgatttt
      721 gatgtatctc tcttttcatc ctcatattat tctattgatt ctcgccttat ttgtcaaatt
      781 aggatagttt tttattaatt gggaatctaa acagacgaaa aaatatgcga aagaagcact
      841 aaaaaattta tctcataaat ttttaaaacg ataattctgg atgacgattt ggatattctt
      901 ctgccctcgc cattcattta cctgtggata ataagtcaca tccatccata tatgatgtga
      961 caggcctttt tgaattctct gtgcctcttc ttttccacaa aaagagatga gttcttctaa
     1021 aaatacatcg gattctccaa aatacatggc atctatgctt gttccattgg catccgacag
     1081 gaagagtttt aaacatctgc ctgttgttcc gagtacccgc attcctttta tgtaaaggtc
     1141 tttttgtgca aagagcggtt ttgtgttttc atttccaaat ggttctagta attcaaattc
     1201 attgatgaga ctttcggata aataagatat cggcaaggct acatcaatgt gaactttttc
     1261 tgcgaaatca tcttcggtaa gggttgcgtt ggcatttaat ttttcccgga attcttctaa
     1321 gcggtcttcc tgcatagaaa atcctgctgc catcgggtgc ccaccgaatt tatcgaaaca
     1381 ttccttgatt ttgttcattt ccttatacat atgataggct tcgatagaac ggccagagcc
     1441 ttttaatcct tcttttgttc ttgtgatgac aaatactggc ttatggtaat gttctttcat
     1501 tcttccggca ataattccgg cgatactttc gtgacagttt ggaagatata caacaagtac
     1561 cttatcgttt gcatgtcccg tgctttcgag atattctttt gcagctttta ccccgttagc
     1621 tgtcatttct tttcgctctg catttagctg tgtgagtgct tctgctttct gcctgcaaag
     1681 ttctttatct tcgcatagaa gaagttctaa cgcatctttt gcagaggtca aacgaccgga
     1741 agcattaata cacggaccga gaataaatcc aaagtgataa gaagatatct ttttttcttc
     1801 aagatgattt gcctcaatta aagcttgcag cccggtaata ttcgtatgct gtatccgtcg
     1861 caggccttcc tttacgataa tacggttctc atcacacaat ggcataacgt cacagactgt
     1921 tgccatcgcc gcaatctcaa gaaatacttc actttctcta cggtcaattc caaacaaatc
     1981 ataaagcacc tgaataaact tgtagacaac aaccgctccg catatatttt caaatggata
     2041 cggacaatct ttttgcttcg gattaataac ggcagcggct gacggcaaat tataagaaat
     2101 gcttccatct tcttgccttt gaaacggaat atcatgatga tctgtcacaa tcagggtgag
     2161 tcctaaagaa tttccataag caatctgttc tgctgccgca attccattgt cacaggtgat
     2221 aatcgtatca attccgtcct ctgctgcctt ttctatcaga tgttcattaa ttccataacc
     2281 gtcttccaca cggtcaggaa tcttataatc aacatccgca ccacagcgtt ttaatccctg
     2341 atataaaata tagtttgatg aaacaccatc tacatcataa tccgaaataa tccgaatctt
     2401 tttgcctgtt tctatcttct cttttatgat ttccgctccc ttatcggcat ctttcaaaag
     2461 atgagaatca tataaatcag acagagaacc ataaagataa cgctgcattt ccctaactgt
     2521 tgttaagctc ctatttctca tcagacgcgc cgttaccggg ctgatatgaa atatctcacc
     2581 aattttatta aaatctgctc tttttgaagc gataaaccac ttttccatct attcttcttc
     2641 gccttctgta tctgctaatg cagccttaat cataattgcg cattctactc tcttacgctc
     2701 catatcgcaa cttaaatcat aagaatcatc aattgttcca tggaaattat aagagtttgc
     2761 aggacagccg ccgctacagt agaatctcgc aaaacagtct ttacattttt tctttgtgta
     2821 tacgttgcag gaacggaatt cgtcacaaat atcggtacgc ttgattccat caaaaacgtt
     2881 accaagaagg aatttctctt ctcctacaaa ctggtgacaa ggatataaat ctccccatgg
     2941 tgttactgct aaatactctg ttccgcttcc acagccggaa agtctttttg ctacacatgg
     3001 accacctgta aggtcaatca taaagtggaa gaaattaaag ccttttcctg ctttttctct
     3061 cttaatcatt tcttttgcaa gtctgtcata ctcatcaaaa atctgtggaa ggtctttttc
     3121 ctgaattgcg tacggctctt ctggctgtcc aacaactggt tccatggaaa tctgttcaaa
     3181 tcctaagtct gcaagatgaa gaacatcttt ggaaaaatca agatttctat tggtaaatgt
     3241 tcctcttaca tagtatttct gctgatgtct ggactctgca aaacggataa acttcggcat
     3301 gataaggtca tagcttggct taccatttct tgtaggacgc atgtaatcat ggatttcttt
     3361 acgtccatcg acacttaaaa caacgttgtc catttcttta ttggcaaatt ccataatctc
     3421 gtcatttaac agcacaccat tggttgtcaa agtgaaacgg aaatgtttgt tatgtttttc
     3481 ttcaagagaa cgtccatatt ctacaacttc ctttacaaca ccgaagttca ttgttggctc
     3541 accgccaaag aagtcaactt caagattatg acggtttcca gaattggcta caaggaaatc
     3601 aagggcagcc tttccaacct ttgcactcat aagttcacgg tgtcctttat actccccttc
     3661 ttctgcaaaa cagtagcggc aggcaagatt acaatcatgt gcaatatgca ggcaaagtgc
     3721 ctttactact gtctttctgc tctttacctc tttaatatag tcttcataaa tatcttctgt
     3781 aaataaaagt ccctcttctt ttaaagaagt tacctcttta tatgcctctt caatatcctc
     3841 cttgctgtaa gaaagttcat tttctatttc ttctaagctt ttttcttcat ataaagcaat
     3901 gacatcataa gttacatcat caacaacatg aatggcacca ctgcacacat ccatgacaat
     3961 attatatcca ttatttttat actggtgaat cacgttaaat atccctttct atttctttta
     4021 tagtttttat acttaatttt ctaaaatata tttttaattt gaagatatgt cctgctaact
     4081 ttaaaataga tatataatac agaacattcc tgtatacaat attttcaact tacaataaag
     4141 taatctctgc aaacatactt ttccatacaa gagataaggt gaactgacaa aaaagacagt
     4201 tcaccctact tcaagcatat atcaggaagc attcttcctg ttgtgctctc taattattta
     4261 ttactctcgc aagtctggtt acctactgta caagatgtct tgcaggcaga ctggcaggat
     4321 gtctggcact cgccgcatcc acctttacac attgtagtac cgtaagtttt gtttccggtc
     4381 agtgtcttta cacgtttcat taataacgcc tcctcacttc atgatctagt atgtaaagca
     4441 tctaagatga cactttgtag gttattataa cacaaaccct cccgtaagaa aagaactttt
     4501 tagcttaaca ttcctccaag cattcctcct gccgcacaat aaagcatcat tgtaaaaaat
     4561 gctgtcgtat ctgtcacaaa tgcctgcccc atcccgacgc gtattactcc aaaaaacaag
     4621 caatataaaa cacctacgcc aagcccccat aaataccgtt ttttcatatt ctttttccca
     4681 cacaaaaatc ccccgacaaa acaagccatc acactcataa caattaaacc aattttttct
     4741 acggaagcgg aaagattacc tttcaacatg gcaaatgcaa acactgctaa aaatagcatt
     4801 gtgagtaata ctgcaattaa tgcagaaaga aacaggcctg ctgcacgctc catccatttt
     4861 ttatacgaaa ttccatccat aggctgcacc aaaggctttt ttatagccta tgaaaagggt
     4921 tctctgttta gaaca
//
