LOCUS       gnlProkkaIEMLNAAK_8    10378 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IEMLNAAK_8.
ACCESSION   gnlProkkaIEMLNAAK_8
VERSION     gnlProkkaIEMLNAAK_8
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 05:55:45
            Original ID  :: gnl|Prokka|IEMLNAAK_8
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10378
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10378
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[27:378]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      28..378
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10378
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10378
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(28..378)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_1"
                     /sec_met_domain="PqqD_RRE (E-value: 2.8e-10, bitscore:
                     33.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.9e-17, bitscore: 55.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPAGMSKELHVRLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(476..1864)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 95.3; E-value: 4.9e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_2"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGYTDEGGAFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSLMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(2112..2507)
                     /locus_tag="ctg8_3"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(2514..3287)
                     /locus_tag="ctg8_4"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETIKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(3293..3820)
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(3807..5048)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 385.8; E-value:
                     4.8e-117)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQVGTVVTTPVVTTHQPSVPA
                     IIHTMQPAVCKDDDDIQDTEEYVEEPPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(5058..6152)
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(6157..7197)
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQNQIPLGEASKE
                     AEQTNK"
     CDS             complement(7216..8250)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_9"
                     /sec_met_domain="PF04055 (E-value: 1.5e-17, bitscore: 57.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYPLLGMTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDD
                     MTNLSLKHRELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATL
                     CVSSQVGCKMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALELLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAE
                     LMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRV
                     NLIRFHAIPGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEK
                     NNES"
ORIGIN
        1 cctctgtggt gaaatataaa ttcctattta tgcgactggt atcaccagtt ttataaatcc
       61 atctttctgc atttgagaaa gataagccga tacacgcgac tcgtagccct cttcattttg
      121 aaaatggtct gcgagttttt ctataatctc acgaacattg cgttttccat ctatcagttc
      181 ccatacagcc gtaccgtgtt cttccaatcg cacatgaagt tctttcgaca ttcctgccgg
      241 tacaaggaag cgttgcatcc acggatattt aaaacgggga aaggagagca caatcgtctc
      301 cccttccctt tctgctgtaa tatgttcact gcgacaggga atgacctcta acaggttgat
      361 tttctctttg gcagccatac ttcttatttt ttatttcaga gtattcatac tgataccctt
      421 ttgtttacac cttgatacaa aattcctttg ttactttagg tattgaattt cccagttact
      481 tttggatatt cgcctcttcc agaccgtatc ccttcttctt gttctctgcc ttcaacatca
      541 aagccacaat cagagcaagt acaccaaaga gagcaaaaat agtcatcggc aatgtgtaat
      601 cataagtctg tgcaccgtct accaccggac ctttgcaata agtattcaat acccatccga
      661 ttaacaaagg aacacccatc agtccccagt tctgtaccca gaaaatcaaa gcgtaagcag
      721 tacccagctg tttttccgga ataatcttcg gaacagaagg ccacatagcc gaaggcacca
      781 atgagaaagc aaatcccaat ataatcatta taatagtagc aaaccaccat atattcagta
      841 taggcagggc aaacatggta tgtacaaaaa ttagcatcaa tgatccgatc accatcaatg
      901 tggctccttt accgatacgg tcatataacg aaccgaacaa cggagtcagg ataattgcac
      961 caatcggcaa caatccggga atcgttcccg ccagtttcgg atctacatta tatttctgca
     1021 ccatcaagtc ggcagcatat ttgataaaag ggaagacggc cgagtagaac aatacgcaca
     1081 gcaatgcgat caaccagaat cccttattgg taatgatata cacaatatct ttcatacgga
     1141 acggttcttc cggttccaaa ccttctgcat ccaaagaagc atccaatttc ttatcgtaga
     1201 aagtataaag gaagaaagca atagtaccta cacacagcat aatcagacaa aacagaatag
     1261 gagcaggaat attggtatgg aatgcaccac cctcgtccgt atatccgaag aagtctgcca
     1321 aaggaactgt caacaccatc gccagagttg tcccaatacg tgccgtagcc atttcaagtc
     1381 ccatagccaa tgccatttcc ttgcccttga accatttcac tataatcttg gaaacagtga
     1441 taccagcaat ctccacacct acaccaaaga tagcatatcc caatgcagcc aacgtcacct
     1501 gtgttttgaa tccgaagagc atggcacctt ccggaaaagt agtagaaatc gcatagtatt
     1561 tcaatccaca accaaacacc atcaataagc aagctcccat tccggtgaaa cgaactccca
     1621 ttttgtccaa aatgatacca ccgaagatca gcatcaacaa gaatacgtta aaccaaccgt
     1681 aagcgcttgt gaagaatcca taatcaagac tatcccataa tagttctttc tcaagcatgg
     1741 gttttagagg agacattacg tcggtgagga aatagccgca tagcatagta aatgcgacca
     1801 atgctagaac actccatcgg agtacggcgg agtcattcaa tttctgtttc aaatgttctg
     1861 tcattgttat atttaaaaaa gtagttaata atcttataca gccaacaaag gtagttaaat
     1921 ctcgtttgtt tctatcacaa agagattgtt tttacaagaa aaagttaagt gcggattaca
     1981 ctgaccacgc ggaacattga aaatccgtgt aatctgcgta atccgcactt aaatatcaaa
     2041 gaaatgcagc atccgtctgc accttcccat taatggtttt accccaaagt cttacctgac
     2101 gacggagtga attactctgc tgcaggagca ggagtttcag tagccggtgc cggagtttct
     2161 gtagcaggtg cattggtagc aggagcttca gtttgcggcg cagccgtacc tgcgggtaag
     2221 ttatacgggt tagtctgttg ttctttctgt gcctgttcca acactgcgtc tttagcaaca
     2281 gcagaacgag gaactacata agcagtagca atgctcatta caaccataaa gatggccagg
     2341 ccccatgttg ctttttccag aaagtctgta gtcttgcgca cgcccatgat ggcgttagat
     2401 gaagagaaac cagaagcaag tccgcctcct tttgagttct gaatcagcac gatgaaacac
     2461 atcaacaagg ctgcaataac cattaagata acgaataata agtacatttt tagttatttt
     2521 gaattagcgt taataatcaa tttctccaaa aatctgattt ggtctgcaaa gtaagcattt
     2581 ttttttggat atttcaagct taatttttta attatttcaa gagcttttga atatcgttgc
     2641 tgtttaacat agatttttgc caaagtttcc gtaaaacagc tgtcatcttc ctcttcttcc
     2701 tttatcgttt cttcttcggt aagttcgtcc gaagaggttg gcgaagatgg catttcttct
     2761 cttaaaggtt tcatgcagag gggagagtcg ctctcgctct tttctataaa gtcgtcaatc
     2821 agttcgaagc ctttgagttt gggcgtttct tcagccggtt gttccgtggc cggagtctcc
     2881 tccaaaagat aagaagtgta atccatcgaa tagtcgaaac tggtccgggc agtcacctct
     2941 tcgggtactg tggacaagaa agcgtcgatc aatgctaatg tgcggtctac ggacggttcg
     3001 tctttcagca cctccgtgag aggtactccc tttttccgtg cctgcacatc atagcggtca
     3061 ccttcaatca accggaacaa ctgccgtctg tctgcaatgt aaagaactgc tttccgcagt
     3121 tctccaccga aactaatatc atggagaata tacagattct tcagatacaa cagacgaagt
     3181 gactgaaaat acggatacct cgcaagaaga ttgcgcagtt cgtacaaagt atccctattc
     3241 agcgtctcgg gatgctgaat ccattgttga aagttaacag aagtcattta tattaccagt
     3301 ttgctacagt tgcattaaaa atttggtcgg tgatctcttt agacatttca gcaatcaatc
     3361 cgtcctgtac ggcagtcaac aactgggtag agtcgtaggt acggaacgca gaaaactgtt
     3421 gttcaaagtc ttcggcatga ttggtgttgt tgacaaaacg cacattgacg gtgatagtca
     3481 acttcgtctc cgaagaataa ccgtcggcag atactgcctg gttgtactga ttgtaccctg
     3541 tgatttctcc gtcaatctgc aagtcggcat tttgactcgg cttgagcagt tgcagacggg
     3601 tctgccggat gaagatatct ttcaggtcct cattgaattt ggttgccaac ggagcatata
     3661 catactccga cttgatcggg aagtcggcta tcgaaatggt ctttacctta tcataattga
     3721 tagacgatcc gttaaactta taggaaacag tgcacgcaat gactaccaac ggcaagccga
     3781 acagtagcaa agggcgtatt attttcttaa tccaattcat attcttttat ttttctataa
     3841 agtgtacgct cggaaatatt caagtccttg gccgcactct tccgctttcc gtgatgcctt
     3901 tcaagtgctt tgcgtatcat ttctttttcc acttcgtcca gtgacaaagg aggttcttct
     3961 acatattctt ccgtgtcttg tatgtcgtca tcatccttgc aaaccgcagg ctgcatggta
     4021 tgaatgatcg caggtaccga aggctggtgt gtcgtcacta ccggagtagt aaccaccgtt
     4081 cccacttgtc ctacctgccc cacctgtccg gcacgttccg ccatcaggtt gtgcaccatc
     4141 ttcttcagct ccgccacttc ctggcgcata tcgaacagaa cagaataaag aatctcccgt
     4201 tcgctctcaa agcctttact ctcacgcgtt cccatcagcg cgggaagacg ttgcgtattt
     4261 tgtgcgggaa gataattctg caagatagca gcagagatct ccctgttggt ttcaatgata
     4321 gatatttgct cggtgatgtt cttcaactga cgaacgttgc cgggccacgg gtaagccaat
     4381 aactctttct tcgcatcctc cgtcaactgg atagcaggca tccggtattt ctctgcaaag
     4441 tctgcggaaa acttacggaa caacaaaagt acatcgtcac cacgttcacg caaaggcggt
     4501 atttggatag gcaccgtatt caaccggtaa tataaatctt cacggaaacg tccttctgca
     4561 atcgcttgtg tcagattgac attggtagct gccacaatac gaacatccgt cttttgcact
     4621 ttggacgaac ctacttttat aaactcgcca ctctccaaca cacggagcaa acgcgcctgg
     4681 gtaggcatcg gcaactcccc tacttcatca aggaaaatag taccaccgtc ggcttcgcca
     4741 aagtaccctt tccgttcgcc aatcgcaccg gtaaacgcac ccttctcatg cccgaacagt
     4801 tcggaatcaa tcgtgccctc cggaatagca ccacagttga cagcaatata ctgtccgtgc
     4861 ttcctccggc tatattgatg aataatctgc ggaaaacttt cttttccgac tccactttct
     4921 ccggtaatca gcacagacaa atcggtagga gctacctgaa tggcaacatc tatggcgcgc
     4981 gacaatgctt cagtatttcc aataataccg aaacgctgtt tcacttgttg tatctctgct
     5041 ctcgtcatca ctcgttttta atcttcgtcc actgtatcca gcttcagttt atcactatcg
     5101 tcacgtttct cgtaatactg tttacgcaac ggattggcac gagccacttt ttcccgctga
     5161 cgattacgga acacatcgat ggcaacatag attgcctgac ggaaagaatc ttcacaagcc
     5221 aatcccttgc ctgcaatatc gtatgccgtt ccatgagccg gagaagtacg tactaccggc
     5281 aggcctgccg tatagttcac cccgtcttcc atagccaagg ccttgaacgg agccagcccc
     5341 tgatcgtgat acatcgccag gataccgtca aaatgagtat aattgcccga acccataaag
     5401 ccgtcggccg cataaggacc gtagcaaagg attcctttct cttccatttc tttcatggca
     5461 gggataatca cttcctgctc ttccattccc aacaaaccac cgtctccggc atgaggattg
     5521 agagagagca ccgcaatacg cggagcgccg ataccgaaat cctgtttcag acaacgatgg
     5581 aatatcatca gtttctcctg aatcagttct ttggtaatcg tagtcgcgat ctctctgaca
     5641 gggatatgtg tcgtcaccaa agccacccgg aagtcattct tcatcaaaat catcaatgac
     5701 ttatcaccat tgcccagacg ttcttcgata tattccgtat gtccggggaa ggagaactct
     5761 tccgactgaa tcgtatgttt gttgatcgga gctgttacga taacgtctat cagcccttcg
     5821 cgatattctt cgatggcacg ttccaaagcc ccaagcgcag ctttaccggc ttcgggatcg
     5881 ggtttggaaa attccacttt cacctcatca tccgtacagt tcaccacgct caaacggttg
     5941 taccccgctt cggtagcaga gttgacaatg ctgaaattgg tctgtatatc cagcgctttg
     6001 cgatgataag ccgctacttt cggtgagcca taaatgatcg gagtacatag ttccaacatc
     6061 gtagggtcgg aaaatgtctt aagaatcacc tcatagccca ccccgttaat atctccttgg
     6121 gtgataccta tccttatctt gttatcttcc atgtttttat ttattagttt gttccgcttc
     6181 cttagatgct tctcccaatg gaatctgatt ctgctgaact tcattcggaa gtttcagtgt
     6241 atacagagat gcttccatct ggcgtaccag gttgcgtttc attttatcag gtgaataaac
     6301 aaatatttct gctgttataa ttcgttggtt tttctcgtcc agacgagtat gagatacata
     6361 cgggccaccc ataaagtcgc ccttcatacg ccacaggcca cgtgcttcca ttgtgtagct
     6421 gttctgtaca ttgatcggac ggacatcggt cagcaaacta tcggtcgaca tataaacgcc
     6481 ttccttgaat ccggggatat tggctttcat cacggagtca cgtttgtgca caaaatattc
     6541 tttggtaaac gtatccttgt cagtgtacgg ataagagtac atcacaaagt tacggtcggc
     6601 actacctgtg ttggtagagg cccaaaagaa atcatccccg gtctttgaat tagccagttc
     6661 ggcatccacc cagatgtcgc atccgaacaa actgtccact ttctgcgaaa tgaagttact
     6721 atgcttccct tccaggaacg taatctgacg gttcatttcc gcgcgggtaa agaagtcgac
     6781 aatcgtcttt ttgttctctt ccacaaactt ctcaaactct tcttcgttcg gagcctggat
     6841 agtcaatatc atctgcggat tggcatacac gtccttcgca tatttgaacg aggctttcgt
     6901 atatatatcc tgtatatcta caataataat gttacgtatc aacttcagcg tagaatcata
     6961 atctttcggc gaagtataca taatccggaa agaaggttcc gactgcggca aaccgggcat
     7021 atcagcatcg agcgcatcat gtaaagccct tccggcagca cgatcccaaa caccgtgatc
     7081 tactacaacc aaaagctcgt aagcacgacc actagaggtg tgatttcctt tcagaccaca
     7141 agatgcaacg acaaaggcta ccaaagcgat gcataaaata aaagagtact ttttcatgat
     7201 gttcggtttt atatattaac tttcattatt tttctcctgt ttcgctgtcg acagcatacc
     7261 gcaagcggca aaaatatctt cgcccctgga tgaacggata gtggtgaaaa gtccgtgtga
     7321 cgtcagataa tcacgaaaac gggtcatcgt atccatatcc gccccctcga ggtctacccc
     7381 cggtatggca tgaaaacgaa tcagattcac cctgcaatcc agcccgcgaa gaagtttcag
     7441 caactctttg gcatagacct gcgaatcatt gagcccttta aaaacaatat attcaaacga
     7501 aagtcgacgt tgtttactaa aatcatagtt ttttaacagt tccaccattt cggtgattga
     7561 aaacgccttt tccgccggca ttaattcagc acgctgaacg gtcagcggag agtgaaggct
     7621 gatggcaagg tggcagtcat tttcttcaat aaaacgctgc aatcctttcc gtagcccgac
     7681 tgtagaaagc gtgatacgtt tcggactcca tgcgtaaccg taggtagcgg tcagtagttc
     7741 caatgctttc aatacctcat ccaggttatc gagcggctcg cccattccca tcattacgac
     7801 attagtcagt ttgtcccgtt ccggcagcga atgaatctga ttcatgatct ggctggcggt
     7861 caggttagcg gtatacccct gtttaccggt catacagaac ttacagttca tcttgcaacc
     7921 tacttgtgac gacacgcaca acgttgcccg gtcatcatcc ggaatataaa ccgactctac
     7981 aaaatggttc tcacccactt tataaagata cttcaccgta ccatctacag agcgcatttc
     8041 atctaccgga gcttccgctc ccacctcata gttctgcttg agcaactccc ggtgtttcaa
     8101 tgacaaatta gtcatatcat caatcgaggc taccttcttt tcgtaaagcc aggatgcaat
     8161 ctgcttggca gcaaagccgg gcatacccag tctttttgtc aatgattgaa gctctacaag
     8221 agtcattcct aaaaggggat atttagacat tcttctttct gttgatagtt tatatctgca
     8281 aatgtaagga aataaagtcg atttccgtat agcaggaatg taaaagttaa caaaaaaggg
     8341 aagtatgcct ccgttatgat tcaaccacgc tgatatattg aagtagcttt tgcgccattt
     8401 cagaatcctc gccattcttt ttcacttcat gaccgtacgc ctcacggaaa caagccagcg
     8461 cctcttcccg ttcattacaa aagctgtaca aaacccctaa gttctgacaa gccagaatcg
     8521 tatcttcttc ctcccatccc aaatacttct ttcgcagttc gaactctctg aagaaagcct
     8581 ctttcgccat tggataattc tccaacttca cataagcctg tgctttgtaa taatatacca
     8641 gacaggaagc attagggtca gcatcatcgt gaatatccaa agacgtcgca atacgaatca
     8701 cgttatcata gtctttattc atgtaatact gctgcataat atcacatctc aatgcctcat
     8761 atcggacagt cagttccgcc agacgcggtt tttcgctgaa atacatttca tgcagaagag
     8821 actcacggaa gaataaagta gacgcctgct catcgccacg ttcattcatc atccgtttga
     8881 attccctgca tagataatac aactgtttat gacaagcgac gatctgtttt ttattatcta
     8941 tctgtatagc aatgtccaac gcctgattca tcagcatcca tgcttcatcg tatcgtttga
     9001 tataataaag acatttaccc tgcatacgca aacatttagc cactccaccg gacagtctgc
     9061 cattcaacga ctcgtgcatt tcagctactt tccggaattt ctcggcagca ctctcttcct
     9121 catccttata gtaatcacaa taagccagat attcggaaag ttcaatgact tctgcctgac
     9181 tcttctcgtc agcagaagcc gcatgataat caagcgccct attcagatag atcactgctt
     9241 cattgtattg ctcattgtag taatatgcca gagctagatt tcggcaggtg ttggcaatct
     9301 ccagttccgg agtcggtaca atgttttcct gcatcaccaa tgctttcagg aaacagtcgc
     9361 atgccgtttc gtattcttca ttacgggcat accggcatcc ctcattcatc ttcaataccg
     9421 acttggcaat gagtggcatg gcagcacctt ccatactctt ctcactcaca gcagctgccg
     9481 ccttcgtcag atggaaagaa ctgctcaaga aagtagccat atcattagca atgacaggaa
     9541 ttaaaaaaga atcgatctca tcaaagtcca attcggcata gacttcaggc gtaacttcag
     9601 gattgtcgtt catgatcgcc ttccagctat cttccaacaa agaacgattc gtgcgataca
     9661 gaatctcgaa aatctccaca tcacaaatcc aatccttcaa tatatcccat tcttgcatct
     9721 tatagcattg ataggtaatc tccactttat agcgatacga atcatggtag cagaactgtt
     9781 tcatgcgata gttataatcg gcaaaagtca acggatggga aaggatttct tcctcatcca
     9841 gcagagcgga aataatttca tggcgactat catctataca ttcgtcatct tgagcgaaat
     9901 agcgttcgat cgcctctacc atttgtgtgt caccaatgca atatcgtcct cctttgttgg
     9961 tgagccagct gctcatttcc actctcaact gcgaccaaag tatctgatta atgtctgcca
    10021 tgctcttcac ttcatcttcg gtaaatcctt ctaaagtaag tgaaagcatc agaagcgttc
    10081 ttccaatctc ttcggaacca taatcagccg acaaacgccg tagcacactg tcatagaatt
    10141 gcccaacctc attgagccgg caatatccac gcatatattc attgagagca tcgtactgac
    10201 cgaacgaaac cagctcgttg agcaatacac ttaaacagcg cggttgttta gccagcaccc
    10261 acgaagcaag aatatcttcc tgctgtgcag acaaagcctt ggagtaagta gacaaatatt
    10321 gctttgagaa cgacttggca tccgcctgtg aaaagccatt caactggaaa tgagcgca
//
