LOCUS       c00048_gnlPro..        22331 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IEMLNAAK_48.
ACCESSION   c00048_gnlPro..
VERSION     c00048_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 20:41:44
            Original ID  :: gnl|Prokka|IEMLNAAK_48
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2461
            Orig. end    :: 24792
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22331
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[12461:17321]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14860
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..22331
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22331
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             317..3556
                     /locus_tag="ctg48_4"
                     /transl_table=11
                     /translation="MGKRIHLFLLALAIGVIQGAAQVTTVRGIVTTEEDGEPVIGASVI
                     VKGTALGTVTDVNGRFELSGLPPSATRLLISYISLMAKEVAIAPQVSVTLKSDTHLLDE
                     VVVTALGISREKKALGYTAQEVKQDALVQGKDNNLLNSLSGKIAGVRITNTQGDVGSSR
                     IVIRGETSIAGENQPLFIVDGIPVDNSQLNARSSGRDFKNAIADLNPEDIKTLTVLKGP
                     NAAALYGARAAHGAIVITTKGGDKRQKGIGITLHSSTQVSFVATLPEFQNLFGQGAGGR
                     FSYVDGKGAGVNDGVDESWGPRLDIGLLIPQFDSPLDADGNRVATPWVSHPNNVRDYFR
                     MGISTNNGISVARGDDKYQFRVGYNYEKQVSIVPDAGTNKTNISLNTDYHLAKWIVVGA
                     TANYIVYTAPSLPGSATPSGSNVRSNSPMLQFLWFGRQVDTNSLKADYTRNWNSSYYDN
                     PFWSASYNTQSQERHRLIGDLHAEFRLTDGLNVRFRTSTDWYNDRRKSKVKWGSAGAGS
                     PYGSYAEDAYTVKENNTEVLATYIKQLNKNWGIDALLGFNVRNKQYENNYQAAPRLAVA
                     DLYTLTNSRDPLTSSNDFYRLRQYGLYGSIQLDYRRWAFLNITGRNDWSSTLPVDNNSY
                     FYPSVTASVLLSEAFGWRSKAVNYLKIRGGWSQVGADANPYQLATVFTSETVFNGNPLQ
                     SSSTIGMNPNLKPEKTSSIEAGFEAAFWDNRLCLDFTYYKTDSRNQILKLATTAASGYT
                     SQVRNAGHIRNRGYEIQLGAVPIQTSKGFRWNLDLNYGANSSKVVKLDDEGLITSYQLY
                     SSGIQILASVGEAYGTLFGTSYVRDANGNVVVDANGLPKISTTNKTLGKFTPDWTGGIS
                     NTFSYRSLSLSFLIDASVGGSIFSNTNKTGKYTGVLANTLSGRDAEHGGLWYYTAAMGN
                     NVRLPESPSYSVSSDGLYYAQVNGQSTRVYQDGIMVEGVTESGSKNEEVVSAEKYYHRI
                     YSIAEANVYDASYVKLREVALSYRLPRLWTQKLHLQEASVTLTGRNLWTIYKSVPNIDP
                     ESALTTGNAQGVEAYSLPTTRSFGVNLSVKF"
     CDS             3584..5032
                     /locus_tag="ctg48_5"
                     /transl_table=11
                     /translation="MKRRIYFLYIIWVQVVAISLSSCDDELTDINRNPNATENPQPAYL
                     LAAAQYHAANLYWGSSTNYNSTLLWVQHWAKIQYTEPDCYNVDNGSFTTTWDTGYATLI
                     TDLNAIISSELGNDNYRGIATVWRSWVYLLLTNLYGNIPYSEYAQSVTPAYDSQETVLR
                     GLLEELIAADQLLSTTGGTVEGDLIYGNDITRWKQLAHSLRLRIALELADRDEDTARRV
                     IASLWDNRNSVIDSNDAIARFVFTSSPQWNPWASAFNSRDDQRVSKTLIDKLNEWNDPR
                     IGILAQLPQDESVKNYVGAANSLSADAANNQGFNKVSRPGTYFLKDSSPAVFYTYAEVL
                     FIFAESAARGWITADAETLYREAITASLNQFGIIDNRIIDSYLQQEAIRFDAAHWYESI
                     GWQKWIAYYGQGPDAFTDWRRLGYPQLIPGPDSVLGSGELPRRFFYPVTEQSLNGKQYQ
                     IAISHQGADEITTRLWFDVANKER"
     CDS             5104..5754
                     /locus_tag="ctg48_6"
                     /transl_table=11
                     /translation="MNTDITFIIADNQDITRMGMHGYISAIFSGCRMIDVTDKKELMLA
                     LVECNDSVVILDYTLFDINGIEEFLIIEKRFPRVRWILFSNELSEDFIRRMSIERNIGM
                     ILKENSGEEIHSALMCTAHGERFLCHQITNLLIIGSDKPEIHSVLTVTEIDILKLIAHG
                     KSVKEIALERTSSIHTIITHKKNIFRKLGVNNVYEATKYTLRAGLIEMVEYYI"
     CDS             5827..6756
                     /locus_tag="ctg48_7"
                     /transl_table=11
                     /translation="MAKKGELHIRNKHNGQYDFPLLMENYPPLKRFVSLNPLGIQTINF
                     FNPQAVKALNKALLVTYYGIRYWDIPKQYLCPPIPGRADYIHYIADLIQPNGTTPDLPA
                     GDANGQKSKCRCLDIGVGANCIYPIIGHTEYGWTFVGTDIDPVSIENARKIVTCNPVLA
                     HKIDLRLQKDSKKIFDGIIMPDEYFDVTICNPPFHSSREEAEDGTLRKLSSLKGTKINK
                     VQLNFGGSANELWCEGGEVRFLLNMISESQKYQKNCGWFTSLVSKEKNLEKLYTKLKSV
                     NVSEYKVIRMQQGTKSSRILAWRFATNS"
     CDS             6812..7591
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_8"
                     /sec_met_domain="Acetyltransf_1 (E-value: 4.3e-08,
                     bitscore: 23.8, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METNYITLTKENIANEHICCAFSDKKCKDSYELKKEWLKKEFDNG
                     YVFRRIDERAKVFIEYGPAEKAWVPVNAPNYLMINCFWVSGKYKGCGHGKALLQSAIDD
                     AKLQGKDGLVTVVGTSKFHFMSDTKWLLRQGFQTIEKLPYGFSLLSLKLNPAAPDPSFN
                     DCVLSGECPDKDGIVVYYTHRCPFTEFHVRGSLVSAAKSKDIPLRIIELESMEQAQNAP
                     TPATIFTLFYNGKFVTTDLSVCLEGRLSKALGCDSGE"
     CDS             7733..9490
                     /locus_tag="ctg48_9"
                     /transl_table=11
                     /translation="MRFWVCIFVLLFVHNQFSRADKIINNDSLYTEKYIRDIYISNPKR
                     ALQLLDEAETRKAFPLRLINELRSLSYRNMYMNKLAFMYARKSYLLDSISQREPKHMLK
                     MTVYLAELSSIMSKYNESMHYALSGIMQAQKLKDREAEARLLFCIGENNWRLSLKDEAY
                     NYFGRTIELLRGSKDMREMMLLSYYYGAEMGFLMTDSRIDEALALAYEREKLLKKLEKV
                     PEVPEGYIDGQYSYLYAKLAYISYLEKKYAQAEGYYQKYLAIKESHTPDGKMYSIPYLI
                     LSKQYETVIDNCKDFKELLRTQRDTLNAQYLTILNKEVQAYLGLNRYKEAAEIRETIIA
                     ITDSINSTDRKNAALELNAMYGASEKEEYIAEQASQLKIRNVSLCFLACIVVLTLFILW
                     RLWRFNHIIEYKNRMLAKLINEKFANKKDGNQLLEVYEEQEVSSELEPELISPEEQDEL
                     LDETDKESGEEEENKKIFQELNHTVVQKQLYLSPELSREDLAQIVHLNNARFARMIREC
                     TGTNFNGYINGLRINYAIKLMKKYPNYTIRAIADESGFNSAPILYNLFKKKTGMTPYEF
                     KKAQDTLRN"
     CDS             9555..9917
                     /locus_tag="ctg48_10"
                     /transl_table=11
                     /translation="MIQVRIKRVYEDFSETDGYRVLVDKLWPRGMKKEWLKYDYWAKDI
                     TPSPTLRKWFHEDIPGHWGDFVTQYQKELDASPSMADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMRLRE"
     CDS             10001..11233
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_11"
                     /sec_met_domain="HBT (E-value: 2.9e-18, bitscore: 56.5,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKMLELGNYGGFILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNG
                     FALFTYHDDTIITDSPENEHIQNEARLNDLQIIKEEEFSAAVDFAPCKCMLVSDDEEAL
                     LGLEDHWKRRLNGALDVFRSEPYFLEVVPCAIDKANSLGALLEVLGMKREEVIAVGDGV
                     CDVTMIQLAGLGIAMGHSQDSVKACADYVTASNEEDGVAVAVEKAIISEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALAETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVGTVVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             11230..12345
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_12"
                     /sec_met_domain="Chorismate_bind (E-value: 1.4e-57,
                     bitscore: 185.5, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDEEISNLTTIDAFIQRKQPFAVYRIPGEKVPRLLTQAEGAVCL
                     IYDLKELNGQRGFVIAPFQVSETCPVVLIQPDQWGQPLPIDNDTAEEREVALRMQGQES
                     FLTSSTEEYASCFHTFINALRDNTFDKLVLSRHLTIDKVSGFSPLSIFRAACRRYIHSY
                     IYLCYTPQTGIWLGSTPEIILSGEKDEWNTVALAGTQPLQDGKLPQIWDEKNRKEQAYV
                     ASYIRRQLLSLGIHSTENGPYPAYAGALSHLKTDFQFSLKDNKGLGDLLKVLHPTPAVC
                     GLPKEEAYRFILQNEGYDRRYYSGFIGWLDPEGRTDIYVNLRCMHIEDEQLTLYAGGGL
                     LASSELNDEWLETEKKLQTIKRLIATPPLKS"
     CDS             12509..14032
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_13"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1e-07, bitscore:
                     22.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTDERSAGYFAIGLALNGGKPAAVCCTSGTALLNLHPAVAEAFYQ
                     NVPLVVISADRPAAWIGQMDGQTVPQPGVFQTLVKKSVNLPEIHTEEDEWYCNRLVNEA
                     LLETNHHGKGPVHINVPISEPLFQFTVDALPEVRVITRYQGLNVYDRDYNDLVDRMNKY
                     QKRMIIIGQMNLIYLFEKRYIKLLYKHFAWLTEHIGNQTVPGIPVKNFDAALYAMPEEK
                     IDQMVPELLITYGGHVVSKRLKKFLRQHPPKEHWHVSPDGEVVDLYGSLTTVIEMDPFE
                     FLEKIASLLDNRTPDYPRVWENYCKIIPEPDFAYSEMLAVGTLLKALPESCALHLANSS
                     VVRYAQLYSIPPTIEVCCNRGTSGIEGSLSTAVGYAAASDKLNFIAIGDLSFFYDMNAL
                     WNINVRSNLRILLLNNGGGEIFHTLPGLDMSGTSHKFIAAVHKTSAKGWAEERGFLYLQ
                     AQNDEELTEAMKTFTQPETMEQPVLLEVFTNKNKDARMLKNYYHQLKQK"
     CDS             14036..14860
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_14"
                     /sec_met_domain="ECH_1 (E-value: 1.7e-82, bitscore: 266.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTQREWTTIREYDDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKQYPKFP"
     CDS             15050..15946
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_15"
                     /sec_met_domain="MR_MLE_C (E-value: 8.5e-30, bitscore:
                     94.2, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGIGECAPLPALSCDDLPDYEDILIRTCRQVEEEQGKLDKDGLCK
                     YPSILFGLETAIWHFFAGSWALSDTAFSRGEVGIPINGLIWMGDFENMLSQIEKKMEAG
                     FRCVKLKIGAIDFEKELALLRHIRTHFSSKEIELRVDANGAFSPGDAMEKLKRLSEFDL
                     HSIEQPIRAGQWEEMAWLTSESPLPVALDEELIGCNTLEEKKKLLATIRPQYIIIKPSL
                     HGGICGGDEWIMEAEKQHIGWWITSALESNIGLNAIAHWCATFNNPLPQGLGTGMLFTD
                     NIEVPLEIRKDCLWFCK"
     CDS             15978..17081
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 54.7; E-value:
                     2.1e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_16"
                     /sec_met_domain="AMP-binding (E-value: 6.5e-18, bitscore:
                     54.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFDRQQQRLLLEGKEYTFEEISQLIAGGAEAHSPAYWDLYLFLN
                     EWFNDSPVITVHTSGSTGIPKELMVRKDQMMQSARLTCEFLNLKKGESALLCMNLRYIG
                     AMMVVVRSLVAGLNLIVRPASGHPLADIKEPLRFVAMVPLQVYNTLQVPEEKERLKQTD
                     ILIIGGGAVDEALETEINHLPTAVYSTYGMTETLSHIALRRLNGVSASEHYYPFPSVKL
                     SLSAENTLIIDAPLVCDETLQTNDIACIYPDGSFMILGRKDNVINSGGIKIQAEEMEKL
                     LRPFIPVSFVITSVPDQRLGQAVTLLLAGQPDIEEIGNKLQEILEPYYRPKHILTTESI
                     PQTENGKIDRVECRNLAQQLLVSTFAK"
     CDS             complement(17240..18343)
                     /locus_tag="ctg48_17"
                     /transl_table=11
                     /translation="MLENEIWGNSIQNWIISILIIVAAIVLVKLISLLSKKVLKPLTDR
                     TKNHLDDIIFYSLEPPIKFAIILLGIWIAIHRLVYPDSFVKVVDNIYRILIVLDITWVF
                     ARLFGGLLQVYWGHRDGQNNKMLPIIKRTMLVVVWIIGLVMALSNVGVNISALLGTLGI
                     GGIAFALAAQDTVKNVFGAFTLLTDKPFNIGDTIRFDNFEGTVVDIGIRSTRIMNYDKR
                     IITFPNYKITDSSIINISSEPMRRVVLNLGLTYDTTAKKMKEALELLKAIPKRVENVSS
                     NPADVVAVFTEYSDSALVIMYIYFIEKQGDILGVTSNMNMEILDTFNKAGLDFAFPTRT
                     VYIQNDESEHESKDTGKAPESKVDSLK"
     CDS             complement(18387..20354)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_18"
                     /sec_met_domain="Alpha-amylase (E-value: 1.5e-14, bitscore:
                     44.6, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRELKNHPSADQLDSYDKYPCYYGDDLELVYTPKQSVFTLWAPSA
                     GNVRLNLYSSGEGGKPEEQIEMEMADDGVWRTRVNRDLKGSFYTFQIEKDGKWLDETPG
                     IWAKAVGINGNRAAVIDWNATNPEGWESDRAPELKMYSDIILYELHHRDFSIDPDSGIE
                     YKGKFLALTEPGTQTPDGQSTGIDHLKELGVTHIHILPSFDFSTIDETSLEENSYNWGY
                     DPKNYNVPDGSYSTDPANPVARIREFKEMVKSLHEKGFRIVLDVVYNHTASTEHSNFNL
                     TVPGYFYRHNSDGSYSNASGCGNETASEREMVRRYIIESVKFWAKEYHIDGFRFDLMGI
                     HDIETMNRLREELLKIDPTIFIYGEGWAAADSPLPFEQRAVKENVGQMEGIAVFNDEFR
                     DGLKGSTFDEQEPGYASGNINGHFEPVKYGIVGGTRHPQVDYDGLLYCDGPYAGAPSQM
                     VNFVSCHDGYTLVDKLQLSVQGEHAEEELPAIDKLIHTVLLTSQGIPFIRSGEEIMQDK
                     QGEPNSYKSSDSVNRIDWVLKAQNRDIFDYIRGLIALRKAHPAFRIPTVEGLEQWLHFL
                     DTGDSGIIAYTLGEYANGDMWKEILVAYNGNRNEAGIHLPEQDWIVVCKDGQINLDSQE
                     HLPGGDVSIAASSALILYRN"
     CDS             20650..22095
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_19"
                     /sec_met_domain="Alpha-amylase (E-value: 9.5e-36, bitscore:
                     114.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENGVMMQYFEWHLPNDGKLWKQLKEDASHLHDIGVTAVWIPPAY
                     KADEQQDEGYATYDLYDLGEFEQKGTVRTKYGTKDELKEMIDELHKYHIAVYLDVVLNH
                     KAGGDFTEKFMVVEVNPDQRNEALGEPFEIQGWTGYSFHGRKDKYSDFKWHWYHFSGTG
                     FDDSKKRSGIFQIQGEGKAWSKGVDGENGNYDFLLCNDIDLDHPEVVAELNRWGKWVSA
                     ELNLDGMRLDAIKHMKDKFIKQFLDAVRSERGKDFYAVGEYWNGDLETLDNYLESVGHK
                     VNLFDVPLHYNMFQASQEGKNYDLRNILKNTLVEHHCELAVTIVDNHDTQRGSSLESQI
                     EDWFKPLAYGLILMMKDGYPCIFYGDYYSINGEKSPHTKILDILLGARRKYAYGDQIEY
                     FDHPSTIGFIRMGDEEHPGSGLVFLMSNDEAGSKMMSLGKGHKGEVWHEITGSIQDEVT
                     LDEEGNGEFSVDARNLAVWVKKG"
ORIGIN
        1 acttgtttga caataagacg cttgctattc atcctgcaag tactattttt ggaccgttta
       61 ctgataaaca gcgacaggac atggatgtgt tggatacgac tatccgtttc tcaattggtt
      121 tggaggatgt ggatgatctg tttgacgatg tcagacaggc tttgaataat aaaaaggatt
      181 agaagcaaaa atctgaaagt catacacgca actgtaaata taccgcaaat atggtatata
      241 aaatgccatt catacgggat ttatcagttt gtatatatct aatacctttg ccccatcatt
      301 ttaacagtaa acaataatgg gtaaaaggat tcatttattt ttgcttgctc ttgcaatagg
      361 agtgatacaa ggggcagcac aggtgacaac agtgcggggc attgtcacca cagaagaaga
      421 tggggagccg gttatcggtg cctcagttat agtaaaagga actgcattgg gtaccgtaac
      481 tgatgtcaac gggagatttg aactgagtgg actcccgcca tcagctaccc ggctgctaat
      541 ctcttacatt agtctgatgg caaaagaggt agctattgca ccacaggtat cggtaacact
      601 gaagagtgat acgcatctgc tggatgaggt agtagtaacg gctttgggta tttctcgcga
      661 gaaaaaggca ttgggctata cggcacagga agtaaaacag gatgctttgg tgcaagggaa
      721 agataataat ctgttaaatt cgttgagtgg taagatagct ggtgtgcgta ttaccaatac
      781 acaaggagat gttggttcca gtcgcattgt tattcgtggt gaaacttcta ttgcaggtga
      841 gaatcaaccg ctttttattg tggatggaat cccagtggat aattcgcagc ttaatgcacg
      901 ttccagcgga cgcgatttta aaaatgcaat agcagacctg aatccggaag acataaaaac
      961 acttactgta ttgaaaggtc cgaatgccgc tgccctttat ggtgcgcgtg ctgctcacgg
     1021 tgctattgtc atcactacta aggggggaga caaaaggcag aaagggatag ggattacatt
     1081 acattcttcc acgcaagtct cttttgttgc taccttgccg gagtttcaaa atctttttgg
     1141 acaaggggca gggggacggt tcagttatgt agatggcaag ggtgcaggtg tgaatgacgg
     1201 ggtagacgaa agctgggggc cacgtcttga tattggtttg ttgattcctc agttcgatag
     1261 cccattggac gctgacggta atcgtgtggc tactccctgg gtatcccatc ccaacaatgt
     1321 acgcgattat tttcgcatgg gtatttctac aaacaacggt atttctgttg cccgtggaga
     1381 cgacaaatac cagttccgtg taggatataa ctacgaaaaa caagtcagta tcgttcctga
     1441 tgctggaact aataagacga atatcagcct aaatacggat taccatctgg caaaatggat
     1501 tgtggtggga gctacagcca attacatcgt ttatacagct cccagtttgc cggggtcagc
     1561 taccccctcg ggcagtaacg tacgttctaa cagtcctatg cttcagttct tgtggttcgg
     1621 acgtcaagtg gatacgaact cattgaaggc ggactatact cgcaactgga attcaagcta
     1681 ttacgacaat cctttttgga gtgcttctta taatacacag agtcaggaac gtcatcgtct
     1741 gataggtgat ctgcatgccg aattccgtct gacagatggg ttgaatgtgc gttttcgtac
     1801 tagtaccgac tggtataatg accggaggaa atccaaagta aaatggggga gtgcaggtgc
     1861 cggttcgcct tacggcagtt atgctgaaga tgcctatacg gtgaaagaga ataacacaga
     1921 agtattggcg acttatatca aacagttgaa taaaaattgg ggaattgacg ctcttctggg
     1981 ttttaatgta cgtaacaaac aatatgagaa taattatcag gctgctcccc gtttggcggt
     2041 tgctgatctt tatacattga ctaactcgcg tgatccgctc acttcgtcca atgatttcta
     2101 ccgtttacgg caatatggcc tttacggttc catacaactg gattaccgtc gttgggcttt
     2161 cttgaatata acaggacgga acgattggtc gtctacacta cctgtggaca acaattctta
     2221 tttctatcct tcggtgacgg ctagtgtgtt gctttctgaa gctttcgggt ggagaagtaa
     2281 agctgttaac tacctaaaaa tacgtggagg atggtctcaa gtgggagcag atgccaatcc
     2341 ttatcaattg gcaacggtct ttacttcaga aacagttttc aatgggaatc cacttcaaag
     2401 ttcttctacc attggtatga atccgaatct aaaaccggag aagacgtcat ctatagaagc
     2461 aggtttcgag gcggcttttt gggacaatcg cctatgcttg gatttcactt actataagac
     2521 cgatagtcgt aatcaaatat tgaaactagc tactactgct gccagtgggt acacgtcgca
     2581 ggtgcgtaat gccggacata tccgtaatcg tggctatgaa atacaattgg gcgctgttcc
     2641 tatacaaaca tcgaaagggt ttcgttggaa tctggatttg aattatggtg ccaacagcag
     2701 caaggttgtc aaattggatg atgaaggttt gattacgagt taccagctct actcgtctgg
     2761 tattcagata ctggcttcag tgggcgaagc ttatggaacc ctgttcggca cttcatacgt
     2821 gcgtgatgct aatggaaacg ttgtggtgga tgctaacggt ctgcctaaga tttcgaccac
     2881 taataaaacg ttggggaagt ttacgcccga ctggacaggc ggtatcagta acactttcag
     2941 ttatcgttcg ttaagtcttt cttttctgat agatgcaagt gtaggtggtt ctattttttc
     3001 caacactaat aaaactggaa aatataccgg tgtattagct aacacattat cgggccggga
     3061 tgccgagcac ggtggcttgt ggtattatac tgccgccatg ggtaacaatg tacgattacc
     3121 agaatctcct tcttattccg tatcctctga tggactttac tatgcccagg tcaatgggca
     3181 atccacccgt gtgtatcagg atggcattat ggtagaagga gtgacggaaa gtggttctaa
     3241 gaacgaagag gttgtatctg ccgagaaata ctaccatcgt atttacagta ttgctgaagc
     3301 taatgtatat gatgcttctt acgtgaaact gcgagaagtc gctttgagtt accgtctacc
     3361 tcgcttgtgg acgcagaaac tgcatttgca agaagcttcc gttacactga cgggacgtaa
     3421 cttgtggact atttataaga gtgtccctaa tatagatccg gaatcggctt tgactactgg
     3481 aaacgcacaa ggagtagaag cctattcatt gcctacaaca cgttcctttg gtgtgaacct
     3541 ttccgtgaaa ttctaaatgt gaacctttaa ataataggat aagatgaaaa gaagaatata
     3601 ttttttatat ataatatggg tacaagtggt tgccatttct ctatcatcgt gtgatgatga
     3661 attgactgat atcaaccgca accccaatgc cactgaaaat ccacagccgg cttatttact
     3721 tgccgctgcg cagtatcatg ccgccaatct ttattgggga agtagtacga actataattc
     3781 tactctgttg tgggtgcaac attgggctaa aatacaatat acagagccag attgctataa
     3841 tgtggataat ggcagcttta ccactacgtg ggacaccggc tatgcaacgc taataactga
     3901 cttgaatgct attatcagtt cggaactcgg aaatgataat tatcgaggga tagctacagt
     3961 gtggcgttcg tgggtttacc tgttgctgac caatctgtat ggaaatatac catacagtga
     4021 atatgcacaa agtgtaacac ccgcttatga ttcacaagag actgttttgc gcgggctttt
     4081 ggaggagttg atcgctgctg accagttgct ttctaccaca ggaggaacgg tagaagggga
     4141 tttgatttac ggaaatgata ttacccgctg gaaacaattg gcccactccc tacggctacg
     4201 tatcgccctt gaattagctg accgggatga ggatacagcg cgtcgggtta ttgcttccct
     4261 ttgggataat cgtaacagtg taatagatag caatgatgct atagcccgtt ttgtttttac
     4321 ttcttcacca caatggaatc catgggcatc tgctttcaat tcacgtgatg atcagcgggt
     4381 atcaaaaacg ttgattgata aactgaatga atggaatgat ccgagaattg gaattttagc
     4441 ccagctacct caagacgaaa gtgtgaaaaa ctatgtagga gctgccaatt ccttatctgc
     4501 tgatgccgct aataatcagg gatttaataa agtttcccgt cccggtactt attttttgaa
     4561 agatagctct ccggctgtat tttatacgta tgccgaggtc ttgtttatct ttgcagaatc
     4621 cgctgcacgc ggctggataa cggctgatgc ggaaacgctc taccgcgaag ctattactgc
     4681 ttcattgaat cagtttggca ttatagacaa tcgtataatc gattcctatt tacagcagga
     4741 ggcgattcgg ttcgacgccg cacattggta tgaatctatc ggctggcaga agtggatcgc
     4801 ttattatgga cagggacccg atgctttcac tgactggcgc aggctcggtt atccccagct
     4861 tatccctggt cccgattccg ttttgggttc cggagagtta cctcgtcgct ttttttatcc
     4921 cgtaacggaa caatcactga atggtaagca gtatcagatt gccatatccc atcagggagc
     4981 agatgagatt actacccgtt tgtggtttga tgtagctaat aaagaacgat gatacctccg
     5041 tgtctccggg ctgcaatatg cgtttgaaaa atatccgttg aatttaaaaa aaacagaata
     5101 acaatgaaca ctgacattac atttatcata gcagataatc aggatataac cagaatggga
     5161 atgcatggat atatttccgc tatattcagt ggatgtcgca tgatagatgt gacagacaag
     5221 aaagagctca tgcttgcatt ggtagaatgt aatgacagtg tcgttatact tgactataca
     5281 ctgtttgaca tcaatggtat agaagagttt cttattatag aaaaacgttt tccgagagtt
     5341 cgttggatat tgttttccaa tgaattgagc gaagacttta ttcgtaggat gagtatagaa
     5401 aggaatattg gtatgatttt gaaagagaac tccggtgagg aaattcattc tgcattgatg
     5461 tgtacagcac acggggagcg atttctttgt catcagataa ccaatttatt gataatcggt
     5521 tccgacaaac cggaaattca ttctgttttg actgttacag agattgacat tcttaaattg
     5581 atagcacatg ggaaatctgt gaaagaaata gcattggaaa gaacctcaag cattcatact
     5641 attatcaccc ataaaaagaa tattttccgg aagttgggtg tgaataatgt atatgaagca
     5701 actaagtata ctttacgcgc cgggctgatt gaaatggtag aatattatat atgatattca
     5761 gaagagtgtt aggataagag ttaagaagaa tttgtaggca ggaaaattct ctgtatcttt
     5821 gcccgcatgg caaaaaaagg tgagttacat ataagaaata agcacaatgg tcagtatgat
     5881 tttccattgt tgatggaaaa ttatcctcca ttaaagagat tcgtatcgct caatcccctc
     5941 ggaatacaaa ctataaactt ttttaatccg caagcggtga aggctttgaa caaagcatta
     6001 ttggtaactt attatggcat ccggtattgg gacataccga agcaatattt gtgtccgcct
     6061 attcccggaa gggcggatta cattcattat attgccgatc ttatccagcc gaacggaaca
     6121 acaccggatt taccggcagg agatgctaat ggacagaagt ctaaatgtag atgtctggat
     6181 attggggtag gtgcaaattg catttatccg atcataggac acactgaata tggatggacc
     6241 ttcgttggta ctgatattga tccggtttcg atagaaaatg cacgaaagat agtgacttgc
     6301 aaccctgtgt tggctcataa gattgacttg cgacttcaga aagatagtaa gaagattttc
     6361 gatggaatta ttatgcctga tgagtatttt gatgtgacaa tatgcaatcc tccgtttcat
     6421 agttcgcgtg aagaggcgga agacggaacg ttacgcaaat taagcagtct gaaaggtacg
     6481 aagataaata aagtgcagct aaatttcggc gggagtgcga atgaactttg gtgcgagggc
     6541 ggagaagttc gtttcttatt gaatatgatt tccgagagcc aaaaatatca gaagaactgc
     6601 ggatggttta cgagtttggt ttctaaagaa aaaaatctgg aaaagttata taccaaatta
     6661 aaatcggtga atgtgtccga atataaagtt attcgaatgc agcagggaac taaaagtagc
     6721 aggatattag cttggcgatt tgctaccaac tcataacaat gagtgaatat cgaactgtta
     6781 tttgtttaac ctattaatta aatagaatat tatggaaacc aattacatca ctttgacaaa
     6841 ggagaatatt gcaaacgaac atatatgctg tgctttctca gataagaaat gcaaggatag
     6901 ttatgaactc aaaaaagaat ggctgaagaa agagttcgat aacggctatg tgttcagacg
     6961 tattgatgaa cgggcaaaag tgtttatcga atacggtcct gctgaaaaag catgggttcc
     7021 ggtgaatgct cccaattatc tgatgataaa ctgtttctgg gtgtcaggta aatataaagg
     7081 ttgcggacat ggtaaggcat tattgcagtc tgccattgat gatgcaaaat tgcaggggaa
     7141 agatgggctt gtcacagtgg tgggcacttc taaatttcat tttatgagtg acacgaaatg
     7201 gctgttgcga caaggtttcc aaacaataga aaaactccct tacggattca gccttttaag
     7261 tttgaaacta aacccggctg ctcctgatcc ttcttttaat gattgcgtgt tgagcggtga
     7321 gtgtccggat aaggatggaa tagtcgttta ttatacccat cgctgcccgt ttacggagtt
     7381 tcacgttcgc ggttctttgg tcagtgctgc taagagcaaa gacattccat tgagaataat
     7441 tgaattggaa agtatggaac aggcgcaaaa tgcacctact ccggctacca tatttactct
     7501 tttttataat ggcaagtttg taacgactga cttaagtgta tgccttgaag ggcgattgag
     7561 caaagcattg ggctgtgatt caggagaata gctgacttgg aaccatgtta cgtctctgat
     7621 atgtttagct aatgtttctt atttttattt tgcaaattta aattgtgtct gcacattttt
     7681 tggaaaatac atacctttgg ataattaatg attaaacacg attaagaatt ttatgcgttt
     7741 ttgggtatgt atttttgtgc ttctatttgt acacaatcaa ttttcaaggg ctgataaaat
     7801 tataaataat gactctttgt atacagaaaa atatatcaga gatatttata tttccaaccc
     7861 caaacgtgct ttacagttgt tggatgaggc cgaaaccaga aaagccttcc ctctgcgtct
     7921 gattaatgaa ttgcgcagtt tgtcatatcg taatatgtat atgaataaac tagcttttat
     7981 gtatgcaagg aagtcgtact tgcttgattc catctctcaa agagaaccta agcacatgtt
     8041 gaagatgacg gtttatttag ctgaactttc atccataatg agtaaatata atgagagcat
     8101 gcattatgct cttagtggaa ttatgcaggc tcaaaaactg aaggacagag aggcggaagc
     8161 tagattgctt ttttgcatag gagagaataa ttggaggctg tcattgaaag atgaggcgta
     8221 taattatttt ggtcgtacga ttgaattact gcgtgggtca aaggatatga gagaaatgat
     8281 gctgctttcc tattattatg gagcagagat gggattttta atgacagatt cccgtattga
     8341 tgaagctttg gctcttgctt atgaacgtga aaaacttctt aaaaaattag agaaagtacc
     8401 ggaggttccc gaaggctaca ttgatggtca atatagctat ttatatgcaa aattggccta
     8461 tatttcttat ttagaaaaga aatatgcgca agcagaagga tattatcaaa aatatctggc
     8521 aataaaagaa tctcatactc cggatggcaa gatgtattcg attccttatt tgattctttc
     8581 caaacaatat gagacagtaa tagacaactg taaggacttt aaagaattgt tgagaacaca
     8641 gcgggatacc ttgaacgctc aatatttaac tatacttaat aaggaagtcc aggcatatct
     8701 ggggctgaat cgttataaag aagccgcaga aatacgtgaa accatcattg caataacgga
     8761 tagcattaac agtaccgaca ggaaaaatgc tgcattagaa ttgaacgcga tgtacggtgc
     8821 ttccgaaaaa gaagaataca tcgccgagca agcctcacag ctaaaaataa ggaatgtttc
     8881 actctgcttt ttggcgtgta ttgtagtgct gaccctgttt atactttggc gtttgtggcg
     8941 tttcaaccat ataatcgagt ataaaaacag gatgcttgcc aaactgataa acgagaaatt
     9001 tgccaataaa aaagatggta atcagttatt ggaagtgtac gaggaacagg aggtttcatc
     9061 agaattggaa ccggaattga tttctcctga agaacaggat gaacttttgg acgaaacaga
     9121 caaagaaagt ggggaagaag aagagaacaa gaaaatattc caggaattaa atcatacagt
     9181 cgttcaaaaa cagctatatc tttctccaga gctctcaaga gaagatttgg cgcagattgt
     9241 acatctgaat aatgcacgct ttgcccggat gataagagaa tgcaccggaa ctaatttcaa
     9301 tgggtacatc aacggactgc gcattaatta tgcgatcaag ctaatgaaaa aatatcctaa
     9361 ctataccata cgtgccatcg ctgatgaatc cggatttaat agtgccccga tattatataa
     9421 cctttttaag aaaaagacgg gaatgactcc ttatgaattt aaaaaagcgc aggacacatt
     9481 gaggaattaa atagttctac taaacaattt tcgtttttcc cggtttatct attgataact
     9541 aaatattaat ggaaatgata caggtaagga taaagagggt ttacgaagat ttttcagaaa
     9601 cagatggata ccgggtgttg gtagataaat tatggccacg cggaatgaag aaagaatggt
     9661 tgaaatacga ttattgggca aaagacataa caccatcccc tacattacgt aaatggtttc
     9721 atgaagatat tcccggacat tggggagatt ttgtcacgca gtatcaaaaa gagctggatg
     9781 cttctccatc aatggctgat tttctgactc ttatcaaacc acatccggtg ataacactac
     9841 tttatgcttc aaaagaaccg gtgtataatc acgcccgaat tcttcgcgat tatctggaaa
     9901 tgcgtttgag agagtgaaat taaagtaatt ttatctgttt acgctttctg tcgttcactc
     9961 aatttcctac ctttgtaatc taaatcaaaa tcgtgtaatc atgaagtata aattattggt
    10021 tcttgatgta gacggaacac tcctcaatga tgcgaaagaa attagtaaac gtacattggc
    10081 tgccctgttg aaggttcagc aaatgggagt acgtattgtg ctggcgtccg gcagaccgac
    10141 ttatggccta atgccgctgg ccaagatgct cgaacttgga aactatggag gttttatcct
    10201 ttcctataat ggctgtcaga ttatcaatgc acaaaacgga gaaattctgt ttgaacgtcg
    10261 gattaatccc gaaatgttgc cgtatctgga aaagaaagcc cgtaaaaacg gttttgcttt
    10321 attcacttat catgatgata cgatcataac ggattctcct gaaaatgaac atatccaaaa
    10381 tgaagcccgg ttgaatgacc tgcaaataat caaagaagaa gaattttctg ctgccgttga
    10441 ttttgctcct tgtaagtgta tgctggtgag cgatgacgaa gaagcattgc ttggtttgga
    10501 agatcactgg aagagacgac tgaatggggc gttggacgta ttccgttcgg agccctattt
    10561 tctggaagta gttccctgcg ccatcgacaa agccaattct ttgggtgctt tgctggaggt
    10621 gctaggtatg aagcgtgagg aagtgattgc tgtgggcgac ggtgtgtgtg acgtaacaat
    10681 gattcaattg gcggggctgg gtatagctat gggacattca caagactcgg tgaaagcctg
    10741 tgccgattat gtgactgctt cgaatgagga agacggagtg gccgttgcag tggagaaggc
    10801 tatcatatcc gaagtgcgtg cagccgaaat tccccttgac caactgaatg cgcaggcacg
    10861 ccacgcatta atgggaaact tgggaattca atatacatac gccgacgaag atcgtgtaga
    10921 agcaacaatg ccggtagacc atcgtacccg tcagcctttt ggcattttgc atgggggggc
    10981 tactcttgca ctggcagaaa cagttgccgg actcggttcg atgattcttt gccagccgga
    11041 cgagattgta gtaggaatgc aggtcagcgg aaaccatata tcttctgcac atgagggaga
    11101 taccgtgcgt gcagtaggaa ccgttgtaca taaaggacgt tcctcccacg tatggaatgt
    11161 agacgtgttt acttcaacaa acaaactggt gtcttccata cgggtagtca acagtgtgat
    11221 gaaaaagaga tgaccgacga agaaataagt aatttgacaa ctattgatgc atttattcag
    11281 cggaagcagc cgtttgctgt ttaccgtatt cccggggaga aagttccccg tctgttgaca
    11341 caggcggaag gagcggtatg tctgatatac gacctgaaag aactgaatgg acagagagga
    11401 tttgttatcg ctccgtttca ggtgagtgag acgtgtcctg tcgtattgat tcaacccgat
    11461 cagtgggggc aacctttgcc gattgacaat gatacggcag aagaacggga agtcgctttg
    11521 cggatgcaag gacaagaatc gttcctgact tcttctacgg aggaatatgc ctcctgcttt
    11581 cataccttta taaatgcttt gcgtgataat acttttgata aattagtact ttcacgtcat
    11641 cttactattg ataaagtatc cggtttttcc cctttatcta tatttcgtgc agcttgcagg
    11701 cgttatattc attcatatat atacttgtgc tacactccgc agacaggaat ctggttggga
    11761 agcactcccg aaatcatttt atcgggtgaa aaagatgaat ggaatacagt agcgttggcc
    11821 gggacacagc ctttgcaaga tggtaaactg ccccaaatat gggatgaaaa gaatcggaaa
    11881 gagcaggctt atgtagcttc ttacattcgt cgccaactcc tttcgttggg tattcattct
    11941 acggagaacg ggccttatcc ggcttatgca ggtgctttgt cacatttgaa aactgatttc
    12001 cagttttctt tgaaagataa caaaggtttg ggagatctct tgaaagtgtt gcatccaacg
    12061 cctgctgtat gcggtttacc gaaagaagaa gcctatcggt ttatattgca gaacgaaggc
    12121 tacgaccgcc gctattattc cggctttatc ggctggctgg acccggaagg gcgaactgac
    12181 atctatgtga atctgcgctg catgcatatt gaagatgaac aactgactct ttatgccggc
    12241 ggtggactac tggcttcttc ggaattgaat gacgaatggc tggaaacgga aaagaagttg
    12301 caaaccatca aacggcttat tgcaacgcct cctttaaaat cataaactac taataattat
    12361 catcatgtat acagacaaga agaacatact ccagttggtt gcgttgctcg aggcgcatgg
    12421 gattactaag gttgtgttgt gtccgggtag tcggaatacg cccatagtac atactctgtc
    12481 taaccatccg aattttacct gctatccggt gacggatgaa cggagtgccg gctattttgc
    12541 cattggtctt gcgttgaatg gtggtaagcc tgctgctgtg tgctgcactt ccggtactgc
    12601 attattaaat cttcatccgg ctgtagccga agcattttat cagaatgttc ctttagttgt
    12661 catttcagca gaccgtcccg ctgcctggat cggacagatg gatggacaga cagtgccgca
    12721 accgggtgtg tttcaaacgc tggtaaagaa gtcggtcaat cttccggaga ttcatacgga
    12781 agaagatgaa tggtattgta atcgcctggt gaatgaagcc ttgttggaga cgaatcatca
    12841 tggaaaaggc ccggtgcata tcaatgttcc tatttccgaa ccgctgtttc aattcacggt
    12901 agatgcactc ccggaagtac gtgtgataac ccgttatcag ggattgaacg tctatgaccg
    12961 tgattataat gatctggtcg accggatgaa taaatatcag aagcgcatga ttatcatcgg
    13021 tcagatgaac cttatttatc tgtttgaaaa aagatatatc aagttattat ataaacattt
    13081 tgcctggttg acggaacata tcggcaatca gacagttccc ggtattccgg taaagaattt
    13141 cgatgcggca ctttatgcca tgcccgaaga gaagatagac cagatggttc ccgaattgct
    13201 gattacttac ggaggacatg tcgtttccaa acgattgaag aagtttctcc gtcagcatcc
    13261 gcctaaagag cattggcacg tatcgccgga tggtgaggtg gtcgatttgt acggctcatt
    13321 gactacagtg atcgagatgg acccgtttga atttctggag aagatcgcca gcctgctgga
    13381 taaccggact cctgactatc cccgtgtatg ggagaattat tgtaagatta ttcccgaacc
    13441 ggattttgcc tattcggaga tgttggctgt cggtacatta ttgaaagctt tgccggagtc
    13501 ctgtgcattg catctggcaa acagttcggt agttcgttat gcacaactat attcgattcc
    13561 tcctacaatt gaagtttgtt gcaatcgggg aacaagtggt attgaagggt cgttgtctac
    13621 cgctgtcggt tatgcggcag cttccgacaa actgaatttc atagctatcg gagatctaag
    13681 tttcttctat gatatgaatg cgttgtggaa tatcaacgtc cgttccaacc tgcgtatcct
    13741 tttattaaat aacggaggag gagagatttt ccatacttta ccgggattgg atatgtcggg
    13801 cacctcacat aaatttattg cagcagttca taaaacgtca gccaaaggct gggcggagga
    13861 acgtggtttc ctttatctgc aggcacaaaa tgatgaagag ctgactgaag caatgaaaac
    13921 tttcacccag ccggaaacta tggaacaacc tgtgctcctg gaagtgttta ccaacaaaaa
    13981 caaggatgca cgtatgttga agaattatta tcatcaatta aaacaaaaat aaattatgcc
    14041 aacacaaaga gagtggacaa ccatcagaga atacgacgat attctttttg attattataa
    14101 tggaattgcc cgtatcacaa tcaaccgtga acgttatcgg aatgcattta ccccgactac
    14161 tactgccgaa atgagtgatg cattgcgcat ttgccgtgaa gaagcggata ttgatgtgat
    14221 tgtaattacc ggagccggtg ataaggcatt ctgttcggga ggcgaccaga atgtgaaagg
    14281 acgtggcgga tatatcggga aagacggtgt gcctcgtttg agcgtattgg atgtacaaaa
    14341 gcaaatccgt agtattccga aacctgtgat tgctgccgtg aacggctttg ccattggtgg
    14401 cggacacgtg ctccatgtag tatgtgattt atccattgct tcggaaaatg ccattttcgg
    14461 tcagacaggt cctcgcgtgg gtagttttga tgccggattc ggtgcatctt atctggcgcg
    14521 tgtggtagga cagaagaaag cacgtgaaat ttggttcctt tgccgcaagt ataatgcaca
    14581 agaagcattg gatatgggat tggtgaataa ggtagtacct ttggaacagc tggaagatga
    14641 atacgtgcaa tgggcggaag aaatgatgtt gcttagtcca ttggctttgc gcatgattaa
    14701 agcgggattg aatgccgaac tggacggcca ggcaggtatt caggagttgg caggtgacgc
    14761 aacattactt tattacctga cggatgaagc acaggaagga aagaatgcgt tcctggagaa
    14821 acgtaaaccg aacttcaaac aatatccgaa attcccttaa aataataggc taatgaaaga
    14881 ctgattgtgc agtaattagc agattgaaaa gatattcatt atggattgta agatagatat
    14941 tattcctcgg ttgcttcatt tcaagcaacc cgcgggaact tcccggggaa catatactac
    15001 acgaaaagtc tggtatcttc actttacttc tcctgatttt ccgggtagag tgggaattgg
    15061 agaatgtgcg cctttgcctg cgttaagttg tgatgatctc cctgattacg aagatatatt
    15121 aataagaact tgccggcaag tagaggaaga acaaggaaaa ttggataaag atggtctatg
    15181 caagtatcct tccatcttat ttggcttgga aacggctatc tggcatttct ttgcagggag
    15241 ttgggctttg tccgatacgg ctttttcacg tggagaggta gggattccaa tcaacggcct
    15301 gatctggatg ggagattttg aaaacatgtt atcccagatc gagaaaaaga tggaagccgg
    15361 attccgttgc gtcaaactaa agattggcgc tatcgacttt gaaaaagaat tggcattact
    15421 acgtcatatt cgtacccatt tctcttctaa agaaatagag ttgcgtgtag atgcaaacgg
    15481 tgctttctct ccgggtgatg caatggaaaa actgaaacgt ctgtcagaat ttgatttaca
    15541 ttctatcgaa cagccgattc gtgccggaca atgggaagaa atggcttggc tcacttctga
    15601 atctccgttg ccagtagcat tggatgaaga gctgatagga tgcaacacgc tggaagaaaa
    15661 aaagaaactg ctggcaacca tccgtccgca atatatcatc attaaaccat ctctccacgg
    15721 aggaatatgt ggaggggatg aatggattat ggaagcggaa aagcaacata tcggctggtg
    15781 gatcacttcc gctttggagt ccaacattgg tttgaatgct atcgcccatt ggtgtgcaac
    15841 attcaataat ccgttaccac aaggattggg aacgggtatg ctctttactg acaatataga
    15901 agtgcctctt gaaatcagaa aagattgcct gtggttttgt aaatgatggt atttagtggt
    15961 atttaaagga tattctgatg atattcgatc gacaacaaca gcgcttgcta ctggaaggaa
    16021 aagaatacac ttttgaagaa ataagccaac tgatagcagg aggagcagaa gctcattctc
    16081 ctgcttattg ggatttatat cttttcctga acgaatggtt taatgattct cctgttatta
    16141 cagttcatac atcgggctcc acgggtatac ctaaagaact gatggtacgc aaggatcaaa
    16201 tgatgcaaag tgcgcgtctg acttgtgaat ttctgaattt gaagaaaggt gagtcggcat
    16261 tattatgtat gaatcttcgt tatatcggtg caatgatggt ggtcgtacgt tcattggttg
    16321 caggtttgaa tctgattgtt cgtcctgctt ccggtcatcc gttggcggat ataaaagaac
    16381 ctttgagatt tgtggcaatg gtcccattgc aagtttataa cacgttgcag gttcccgaag
    16441 aaaaagagcg attaaaacaa acggatattc tgattatagg aggcggagcc gttgatgagg
    16501 ctctggaaac ggagataaac catcttccga ctgccgttta ctccacttat ggcatgactg
    16561 aaaccttgtc gcatattgcc cttcgtcgtc tgaacggagt atctgcttca gaacattatt
    16621 atccatttcc ttcagtaaaa ttgtctttat ccgcagagaa tacattaatc attgatgccc
    16681 ctttggtatg tgacgaaaca ttgcagacca atgatattgc atgtatctat cccgatggaa
    16741 gttttatgat tctagggcgg aaagacaatg tgattaacag tggaggaatt aagattcaag
    16801 cagaagaaat ggagaagtta ctccgtccgt ttattcctgt gtcctttgtc attacttcag
    16861 ttccggacca gcgtttaggg caggctgtca ctttgttatt ggcaggtcag cccgatatag
    16921 aagaaatcgg aaataaacta caggaaatac tggaacctta ttatcgtccc aagcatatat
    16981 tgacaacaga atccattccg caaacagaga acggaaaaat agaccgtgtg gagtgccgta
    17041 atttggctca acaattgttg gtaagtactt ttgcaaagta atccgtgcct aaaattattc
    17101 tataaactaa tgatgaagac atacttaatg tctaaaaaaa gaatggacta acctctaaag
    17161 aaaggcaagt cgtagagaat cagtaggtca tacaacttgc cttttaagaa atgaagaatt
    17221 aaatggagtt atctgtttct tattttaatg agtcaacctt agattctggt gctttaccgg
    17281 tatcttttga ttcatgttcc gattcatcat tttgtatata aactgtccgt gtcgggaagg
    17341 cgaagtcaag acccgcttta ttgaaggtat ccagaatctc catattcata ttcgaagtta
    17401 cccctaatat gtctccttgt ttttcaataa agtagatata catgatgacg agtgcggaat
    17461 ccgaatattc cgtaaaaaca gcaaccacat cagcaggatt ggaagaaaca ttctccactc
    17521 ttttcggaat ggctttcagt aattccaaag cttctttcat tttttttgcg gttgtgtcat
    17581 aagtcagtcc gagattaagg acaacccgtc gcatcggttc ggaagagatg ttgatgatag
    17641 aagaatcggt aatcttatag ttcgggaaag tgatgatgcg cttgtcatag ttcatgattc
    17701 gcgtgcttcg gatgcctata tcgacaactg ttccttcaaa gttatcgaaa cgaattgtat
    17761 ctccgatatt gaacggtttg tctgtcagga gcgtgaaagc accgaacaca ttctttacgg
    17821 tgtcttgcgc cgctaaagcg aatgcgatac cgccgatacc cagagttccc agtagtgcac
    17881 tgatgttgac cccgacatta ctcaaagcca tcacaagacc gataatccag acaacaacca
    17941 gcatcgtcct tttgataatc ggtagcattt tattattctg accgtcacgg tgtccccaat
    18001 aaacctgaag taaaccgccg aataaacggg caaacaccca ggtaatatcc agcacaatca
    18061 ggatacgata aatgttgtcg actaccttta cgaagctgtc agggtaaacc agcctgtgaa
    18121 tagctatcca gatgcccaat aagataatag caaatttaat gggcggttcg agagaataaa
    18181 agataatatc gtccagatga ttcttagtcc ggtctgttaa tggtttaagt acctttttgc
    18241 ttaatagcga tatcagtttt acgagaacaa tcgcagcaac aataataagt atggaaataa
    18301 tccagttctg gatggaattt ccccaaattt cattttctaa catattcgag ttgattttaa
    18361 ttgtacatca tgataattgt tttgacttag tttctataca ggatcagagc ggaagaagct
    18421 gcgatggaaa catctccacc cggcaagtgc tcctggctgt ccaagttgat ttgcccatct
    18481 ttgcaaacca ctatccaatc ctgttcggga aggtgaatgc ccgcctcatt ccggttgcca
    18541 ttataagcaa ctaatatttc tttccacata tcgccattgg catattcacc caatgtataa
    18601 gcaatgatac cggaatctcc cgtatcaagg aaatgcagcc attgttccaa cccttctact
    18661 gttggaatgc gaaaggccgg atgtgcttta cgcaatgcaa tcagccctct tatatagtcg
    18721 aaaatatcgc ggttttgggc ttttaaaacc cagtcaatac ggttaacgga gtcggaagac
    18781 ttgtaactgt ttggttcccc ttgcttgtct tgcatgattt cttcgccact acggatgaaa
    18841 ggtattcctt gtgaggtcag aagtactgta tgtattaatt tgtcgatagc gggtaattct
    18901 tcttccgcat gttcaccctg tacggatagc tgaagtttgt ctaccaaagt atatccgtca
    18961 tggcaagaaa caaaattgac catttgcgaa ggagcaccag cgtaagggcc gtcacaataa
    19021 agtaagccgt cataatccac ctgaggatgt cttgtgccgc cgacaattcc gtattttacc
    19081 ggttcgaaat gtccgtttat gtttccggaa gcatatcctg gttcctgttc atcaaacgta
    19141 cttcctttca agccgtcacg aaattcatca ttgaaaacgg caatgccttc catctgccct
    19201 acattctctt tgactgcccg ttgttcgaaa ggcagcgggg agtcggcagc cgcccaacct
    19261 tcgccataga tgaaaatggt cgggtcgatt ttcagcaatt cttctctaag gcggttcatt
    19321 gtttcaatgt catgtattcc catcaggtca aagcggaaac cgtcgatatg atattctttt
    19381 gcccagaatt tcactgattc aataatgtaa cgacggacca tttcacgttc cgaagctgtc
    19441 tcattcccgc aaccggacgc attggagtag gagccgtcgg aattatgccg gtagaaatat
    19501 cctggaacgg ttaaattgaa attagaatgc tccgtcgagg cagtatgatt atacactaca
    19561 tcaagaacaa tacggaaacc tttctcatga aggcttttaa ccatttcctt aaattcccgg
    19621 atgcgggcga caggattggc aggatcggtg gagtaacttc cgtccggcac gttatagttt
    19681 ttgggatcat atccccaatt ataactgttt tcttctaagc ttgtttcatc tattgtggag
    19741 aagtcgaaag agggtaggat atggatatgt gttacaccta gttctttcag atggtctatg
    19801 ccggtcgatt gtccgtcagg agtttgagtt ccgggttcgg tcagggcgag aaactttcct
    19861 ttatattcaa ttcccgagtc cggatcaatg ctgaaatcac ggtgatgcag ctcataaaga
    19921 ataatgtccg aatacatttt tagttcaggc gcccggtctg attcccaacc ttcgggattc
    19981 gttgcattcc agtcaattac agccgcgcgg ttgccgttga tgccgactgc ttttgcccaa
    20041 atgccgggtg tttcgtccag ccattttcca tctttttcta tctggaaagt ataaaaagaa
    20101 cctttcaagt cacggttgac acgggtacgc cacacaccgt cgtcggccat ttccatttcg
    20161 atttgttctt ccggttttcc gccttctccg gacgaataca ggtttaatcg gacgttgccg
    20221 gcactgggag cccaaagtgt aaatacggat tgttttggag tatagaccaa ctccaaatca
    20281 tctccgtaat aacacggata tttgtcatac gaatccaatt gatccgcgga cggatgattt
    20341 ttcaattctc tcatgcattc taatttaata ttaatactat ataaataatt taatgaacaa
    20401 gtggaataaa tgaaccggta aattccgtta tggtatgatg caaaacaaat agaaaattaa
    20461 aagttcctgt gcttgtcttt gtaaataaga aaataaaagg aataattaat ataaatttac
    20521 tctgttgtga atcagagttt tatcctttgc aatttttcat gtttgttagc ttataattca
    20581 tgataacgaa ggaactttgt taacatcagc tttgttttat acattgttaa atataaaaaa
    20641 gagacagata tggaaaatgg tgtaatgatg caatattttg agtggcatct cccgaatgac
    20701 gggaaattat ggaaacaatt aaaggaagac gcttcgcatc ttcacgatat tggtgtgacc
    20761 gcagtatgga ttccgcctgc ctataaagcc gacgaacagc aggatgaagg atatgcaacc
    20821 tatgatttgt atgatttggg cgaattcgaa caaaaaggaa cggtaaggac gaagtacggc
    20881 acgaaagacg aactgaaaga gatgattgac gaattgcaca aatatcatat tgcggtttat
    20941 ctggatgtgg tgcttaatca taaagctgga ggtgatttca ccgagaaatt catggttgta
    21001 gaagtcaatc cggatcaacg gaacgaagct ttgggagaac cgtttgaaat acagggatgg
    21061 actggataca gtttccacgg tcgcaaagat aaatattcgg atttcaagtg gcattggtat
    21121 catttttcag gaacaggttt cgacgattca aagaagcgga gtggtatctt ccagattcag
    21181 ggagaaggaa aagcctggag caaaggagtg gacggtgaga atggaaatta tgatttcctt
    21241 ttatgtaatg acattgactt ggatcatccg gaagtcgttg ccgagttgaa ccgttgggga
    21301 aagtgggttt ctgccgaact taatcttgac ggaatgcggt tggatgccat taagcacatg
    21361 aaagacaaat ttataaaaca attcctcgat gcggtaagaa gtgagagagg aaaagacttc
    21421 tatgctgtcg gcgaatattg gaacggtgat ttggaaacac tggacaacta tcttgaatct
    21481 gtcggacata aagttaattt gtttgatgtc ccattacatt ataatatgtt tcaggcatcg
    21541 caggaaggca aaaactatga cttgaggaat attctgaaga atactttggt cgaacatcat
    21601 tgtgagctgg ctgttacgat tgtcgataat catgatacgc agcgtggcag ttctcttgaa
    21661 tcacaaattg aagattggtt caaaccattg gcttatggac tgattttaat gatgaaggac
    21721 ggctatcctt gtatctttta tggagactat tacagtatta acggcgagaa atctccacat
    21781 accaagatat tggatatttt gttgggcgcc agaagaaaat acgcttatgg cgaccagatt
    21841 gaatatttcg atcatccttc cactattggc tttattcgta tgggcgacga agagcatccc
    21901 ggctctggtc tggtttttct gatgtctaat gacgaggcgg gtagtaaaat gatgagttta
    21961 ggcaaagggc ataaaggcga agtgtggcat gaaatcaccg gaagcattca ggatgaagtg
    22021 actttggatg aggaaggaaa cggtgaattt tccgttgatg cccgcaatct tgccgtttgg
    22081 gtaaagaaag gttgagcctg cattactgat atctctttcg gatatttgtg tttaaatact
    22141 attttacgcc tggatcatta atagtaaagt tattcttcat tatagataaa cttgttttgg
    22201 gttaatagtt aacttgtttt tcacctatta taaactataa atgcaagctt tgattatata
    22261 attgcaagtt tcatttttgt atttataacc atagaacaac caaaactaat cagaaatatc
    22321 cgagtgtaaa t
//
