LOCUS       c00022_gnlPro..        15920 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NMAFLHHN_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:13:35
            Original ID  :: gnl|Prokka|NMAFLHHN_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15920
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15920
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2940:5920]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2941..5920
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15920
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15920
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(221..1579)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.1e-48, bitscore:
                     156.2, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTGIRFRAVPNGHEFTSLLLAVLNCDGKGKNIPDESICARVRAL
                     NGPIKLTTYVSLTCTNCPDVVQALNVMATLNSRITHETVDGAINQKEVEAMKVQGVPSV
                     FADGKLINVGRSDLGELLSKLEAQYGINEGGVDNSVEKPVKNYDVLIVGGGPAGAASAI
                     YSARKGLNVAVIAERIGGQVKETVGIENLISVPQTTGQQLANDLLTHINDYPVDILEHR
                     RVDKVELDGSAKLLTTSTGERFSAPALIVATGASWRKLNVPGEADYIGKGVAFCPHCDG
                     PFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADQVLQEKAKSLPNVEVF
                     LHSQSLEVLGNGDKVTGLRVKDRKTDAERVIDLDGIFVQIGLAANSGVFRDVVETNKPG
                     EIVIDAHCRTNVPGIYAAGDVSTVPYKQIIIAMGEGAKAALSAFEDRMRGLIG"
     CDS             complement(1791..2357)
                     /locus_tag="ctg22_2"
                     /transl_table=11
                     /translation="MEPIINSQVPEFKVQAFQNGSFKTVSSEDIKGKWAIFFFYPADFT
                     FVCPTELVDMADKYGKFQEMGVEVYSVSTDSHFVHKAWHDASETIRKIKYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKIAEIHDNGIGRNADELLRKVEAAQFVASHP
                     NEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             2807..2938
                     /locus_tag="ctg22_3"
                     /transl_table=11
                     /translation="MDMGHYIYFTNCKGDVTSIESDSVRTVNRISRKPIIIKEQTLD"
     CDS             complement(2941..3663)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 73; E-value:
                     9.4e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_4"
                     /sec_met_domain="Radical_SAM (E-value: 1.9e-35, bitscore:
                     114.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGRIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWEVKR
                     ETPYLLEPEALLAEVLRYKNFIAKGGVTVTGGEPLLQPEFLKEFFRLCRENGIHTALDT
                     SGYICSGKALEVLEQVDLVLLDIKTIDAGLHPRLTAVKLDNTLRFLDELEKRGIPVWIR
                     HVIVPGLTDDDEALSKLAEYISSYNVVQKAELLPYHTMGAYKYEAQGLDYKLKGVEPLS
                     AERLANAKAIFMKHGVTV"
     CDS             complement(3680..5920)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_5"
                     /sec_met_domain="Gly_radical (E-value: 4.3e-45, bitscore:
                     144.5, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.4e-281, bitscore:
                     926.2, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENENWAQFKGETWKKEINVRDFIQNNYKPYNGDDTFLVPSSE
                     KTKKVWNKLTEMFKVEREKGVYDAETKLPQGIDTYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTDEMIAARRSAIITG
                     LPDAYGRGRIIGDYRRVPLYGTQILIEEKKRFQKRLDIQELTEEIIQSREEITEQIKAL
                     KAFERMCAGYGFDVTRPAKDAREAVQFLYLAYLAAVKDQDGAAMSLGRTSTFLDIYIEK
                     DICEGKLTEEEAQELIDQFIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTKTSYRYLHTLYNLGPAPEPNLTVLWFNNAPDNWKNFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQYFGARANLAKCLLYAINGGRDEKSGVQVAPRFEPITS
                     EYLDYNEVMEKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMGLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVKVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVDITEKFM
                     EYLRQHQTYRKATPTQSILTITSNVVYGKKTGTTPDGRPGGTPFAPGANPMNGRDTKGA
                     VAALASVAKLPFQHAHDGISYTFAVSPATLGKERDIQINNLVSLLDGYFTPDGGQHLNV
                     NVFDKDLLVDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINSSL"
     CDS             complement(6347..9076)
                     /locus_tag="ctg22_6"
                     /transl_table=11
                     /translation="MNKRFSTLLAAALVAGSFSSAFAQLEGRNVEWKDAQASRAYYLAG
                     VHFVSPTDYLQAFSLQGLVNGADITAANPVAAAQWTVETKKVGTVTHYAFKNIEGEQYL
                     AFEKKDGAYALAAKKEANDETKSFRWFTVAANGNLQAVLSDEKEPYFLGLKNDGTADWS
                     LALLQSSEHHTDGSTSVIKKKVALYEIYNDQITAEAFASKFGENFTIEFPETLDDMDVF
                     ENVSVEKIANDNLGFKLVDNKGTKDTKDDEYVVLANERVSNSELAANAIGYRYAKMTAK
                     AIKDKKIDDKNTVFYAEENETNIGDGKYALVQKVKVGDLDNKDVTFGKVTNDETTRQLA
                     SVEYDCHSTFMGVTVGKGTRVANTEVANERMLIVNVTAKVADKKNSSALGLKNDFTGAR
                     WYDKVSEADFDQPQGQWLVAAGSAANTIKLINVQKPGFVQDNIRLYEAEGENTYTVFAS
                     DLGLSGLETITLTKVEDYDKLNGYYSTLSDINQKFAFVTTGEYANEEAGSDLYLKAGVE
                     GDVVTVVPHAGSEWELIRNEKAQAVTANYKYYDGEKWVELNGKGNEEKGILPADTVRLA
                     YSYAINADELGLGTAWKMAKDDIEFFLKENGKGTYAIVYGATADEVKEYGVINGSEELV
                     AETTDFTNSTPFEIIDLDAAPSLAADSKHMTFEATNSIGFIASDENNNAVLAKETAALW
                     VDSVNAEGYATPKFFISYAGKMMTTAKKFKEIVDKAYANDEISKKEYAELTADENLYYK
                     SVERIKFVDAERLSGEDTLVIADEKYTGKDIEDFKFKVTENEDGDYVLKANGNYVYVIN
                     GNLVYGTDAKEAEAFVIEVTSAPTANEGIATSEVKVIAGEGNVTIAGAAGKKVVICNIL
                     GQVVANTVVSSDNATIAAPAGVVVVAVEGEAAVKAIVK"
     CDS             9756..10190
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="MKEKIDSSDIPTSYLLCMKQDCPKATTCLRRIAEQQIGDEVKLWH
                     VISPKYQEKQTDRCAYFRPADKLTYALGFIGMLDRMPYKLMQEAICKLMRRFGRRTYYR
                     VRKGERPLSPDEQKSMLNILKQCGINDPGKFDAYFEAYDW"
     CDS             10779..12119
                     /locus_tag="ctg22_8"
                     /transl_table=11
                     /translation="MKRLTNLLAITLLTSCVTAFAQEQEETTTEKSAVEQSADIYAAGY
                     NKFRFGGYGEILANFMDYGINRFRGTDNGSKKDHRNSISIPRFVLAFDYKFNSQWVLGA
                     EIEFEAGGTGSAYEIENTENGEYEMEVEKGGEVALEQFHITRLIHPAFNVRAGHLIVPV
                     GLTNEHHEPINFFGTSRPEGETTILPSTWHENGIEVFGTFGRGYTRFNYQALVVAGLNA
                     NGFDRNTWVAGGKQGLFETDNFTSPGYVARLNYLGVPGLKIGGSFYYCHNTGANSDKPE
                     TYVKYGNIPLRIYTADLQYKNKYVTARANMIYGNLSKADDLSSVNNHQSGGSPYTQTTP
                     IAKRAVSYGGEVGFNLRAVCKDNMSVPVIYPFVRYEYYNPQEKGEGKHTMDLRNKVSMW
                     TAGANWYALPNLVVKADYTTRKIGGGKYNSENEFSLAIAYIGWFLSK"
     CDS             12156..13421
                     /locus_tag="ctg22_9"
                     /transl_table=11
                     /translation="MKKKNYFYLAALSLAMTFSMGACSDNNDPNPDGGGKDPVNLDYSS
                     ENASAWGNYMYNVAMLLNDDATMLYNSWVTDYVDEQGSHGPYATIFKDQTAGAYQSPLS
                     CIEEMIESGMWNIANEVGDAKIKDPYTKYTSGDKEGGLYAVESWYSWHSRDDYTNNIFS
                     IRNTYYGRIDDNDVSKVDGNLSAFNSYKDFDDEGDIAEHSLSKLIASTNPALDEEIKTL
                     IFASAKAIQAIPQPFRNNIDSEESVAAMNTCMELANLLLNEVKPYVNQTFGDPEYDDDL
                     DAIAEQFVDAVVLPTYKDLQEKNKLLLDAVNQFRQNPSNDNFEKACNLWITAREPWEKS
                     EAFLIGPVANLGLDPNMDSWPLDQNGIVQVLNSQNWDDLEWSGNFDEEDEAIGAAQSVR
                     GYHTLEYLLFKDGQPRTVDGAK"
     CDS             13457..13561
                     /locus_tag="ctg22_10"
                     /transl_table=11
                     /translation="MTNLETADKCPLFQGFRVITQCDSRYSEINSENQ"
     CDS             13568..15001
                     /locus_tag="ctg22_11"
                     /transl_table=11
                     /translation="MKQSYLLTSSLFLLFACAACEEDDKMDMDKIDVPNGYALSAGTST
                     IFLNSSVAYDTNADWITGANSIRFNNGDGLYDDVRTSNNGDGGGLGPVYAGYSCGSCHR
                     NAGRTKPTLWENGGSGNYGFSSMLVYISRRNGAFFRDYGRVLHDQAIYGVKPEGKLSVT
                     YDKQTFSFPDGETYELCKPNYTITEWYKDSIAPEDLFCTVRIPLRHVGMGQMMAIDRRE
                     IEALAAKSNYPEYGISGRCNYITEKGVTGVGLSGNKAQHLDLTVELGFSSDMGVTNSRY
                     PEEICEGQAQINQGSMMGLSYDQLDISTADMEDVDLYMQSLGVPARRNINDPQVILGEQ
                     KFYEAKCHLCHVTTLHTQAGGSTLLNGTRLPWLGGQTIHPYSDFLLHDMGSEIMGVGLN
                     DNYVSGLARGNEWRTTPLWGIGLQEKVNGHTYFLHDGRARNLTEAIMWHGGEGEASKNL
                     FKQMSKEEREAVIAFLNSL"
ORIGIN
        1 acgcttgaat attaatagct acaaccttcg tagtgataga gtgatagagg atttgtagaa
       61 acttcgtatg gagatcacaa ccttggaaaa ttttgatgcg gttgccctgt tgtgaaagtc
      121 ggggttttgt gcgtaaaaaa aagaaaaggt gtgcaatttt gaacacacat tcatgcagtt
      181 caatattgca caccttcgtc attcacaaca aatacgaata ttaaccgatt aaacctctca
      241 tacggtcttc aaaagcagac agagctgctt tcgctccttc tcccattgct atgattatct
      301 gtttgtaggg tacggtcgat acgtcgccag ccgcatagat gccgggaaca ttcgtccgac
      361 aatgcgcatc gattacaatc tcacccggtt tgttcgtttc gacaacatcg cggaaaacgc
      421 cactgttggc tgccaagccg atttggacaa agattccgtc caggtcgatc acccgctccg
      481 catccgtctt acgatctttt acacgaagac ctgtcacctt atcgccatta ccgagcactt
      541 ccaaagattg ggaatgcaag aaaacttcca cattcggcaa gctctttgct ttttcctgca
      601 acacttggtc ggctttcagt tcgtccataa attccagaac cgtcactttc gaacaaatgc
      661 cagccaaatc tatagctgct tcgatacccg aatttccacc gccgacaacc gctacgtgct
      721 tacctttata gaacggaccg tcgcagtgag ggcaaaaagc gacacctttt ccgatatagt
      781 ccgcttcgcc cggaacattc aacttgcgcc agcttgcacc tgtcgccacg ataagggcag
      841 gagcagaaaa acgttcaccg gtagaagtgg tcagaagttt tgccgatcca tccagttcga
      901 ctttatccac acggcgatgc tccagtatat cgaccggata gtcgttgata tgtgtcagaa
      961 ggtcgttcgc caactgctgt ccggtagtct gaggaacgga aatcaggttc tcgatgccga
     1021 ccgtttcttt gacctgtcct ccgatacgtt cggctatcac tgcgacattc aagcctttac
     1081 gtgccgagta gatagcagaa gctgcaccgg caggtccacc tcccactatt aacacatcat
     1141 agttcttaac aggtttttca acagagttat caacaccccc ttcattaatt ccgtattggg
     1201 cttcgagttt ggaaagcaat tctcccaaat cactacgccc cacattgatc agtttgccat
     1261 cggcaaaaac agaagggact ccctgtactt tcattgcctc aacttctttt tggttgatag
     1321 cgccatccac cgtttcgtgg gtgatccggc tattgagagt agccatgaca ttgagtgcct
     1381 gcactacatc cggacaattg gtgcaagtaa gagaaacata agtcgtcagc ttgatcggac
     1441 cattcaaggc tctgacacga gcacagatac tttcgtccgg tatattttta ccttttccat
     1501 cgcaattcag gaccgctaac agcaaagaag taaactcatg tccgttaggt actgcacgaa
     1561 accggatacc ggtaggcata ccgtctttta caattgtaaa ctgaagtcct tcgccatccg
     1621 caacgctgca tgacaaatga tccgagcatg atgccacatc accaagcagg tctattagct
     1681 cctgacggct ttcgtgatcg ggagcgactt gtatatcaaa tacatattgg gataccagtc
     1741 cggagaaaat acccgaaagc tggtctttca ttgctgagtc taacataact ttagatctta
     1801 ccaaccaagt cgatactcgg cttcaaggtt gcttcgcctt ttttccactt tgcaggacaa
     1861 acttcgttcg ggtgagaagc aacgaactgg gcagcttcaa ctttacgaag caattcgtct
     1921 gcattacggc cgataccgtt atcgtggatt tcggcaatct tgatctttcc ctcgggattt
     1981 accaggaacg taccgcgata agccataccc tcttcttcaa tcatcacacc gaatgcacgg
     2041 cttaaagccc ctgtcgggtc tgccagcatc ggatatttga tcttacggat cgtttcggaa
     2101 gcatcatgcc atgctttgtg tacaaagtgc gagtctgtac ttacggaata tacttcgaca
     2161 cccatttcct gaaatttgcc gtacttgtca gccatgtcga ccaattcggt cggacatacg
     2221 aacgtaaagt cggcaggata gaagaaaaag atggcccatt tgcccttgat atcttcgcta
     2281 cttactgtct tgaaactacc attctgaaaa gcttgaactt tgaattcggg tacttgtgaa
     2341 ttgataattg gttccatgat ttttactatt taatttgtta ctactatttt tgtttaccct
     2401 acaaaggtaa atcgtaagat actgattgaa agaatttttc aaattgataa tttttatctg
     2461 ccgatagacg gatttctatc tgcaagcata cttatctact atgacaatag gaagcaaagt
     2521 aatgttttcc ggaacaataa aaatatacct aattgtaggt aaaatacctt tcgatcatac
     2581 catgtgattc tttaattgtt aactttggat gttaacttaa aaatattcga agatgagaag
     2641 agctagtttg tataatacat tttcagcaag tctattgctc gtttgcaacg catgtctttc
     2701 ttcatgtgtc tcacaaatac cccttacaaa ggaaaaaccg gtaaacaatt ccacttatca
     2761 agtcgaatat ctgttcgaac acgaagggtg taaggtctat cgtttcatgg atatgggaca
     2821 ttacatctat ttcaccaact gcaagggaga tgttaccagt attgaaagcg acagcgtccg
     2881 cacagtcaac cggatcagcc gtaaaccgat catcatcaaa gagcagacac tcgattaggt
     2941 ttatacggtt accccgtgtt tcataaagat cgctttcgca ttggccagac gttctgctga
     3001 aagcggttcc acacctttca gcttatagtc caggccttgc gcctcatatt tgtaagctcc
     3061 cattgtatga taaggcagaa gttcggcttt ctggaccacg ttatatgaac tgatatattc
     3121 ggccagcttg ctcaaggctt catcatcgtc cgtcaggccg ggcacgatca cgtggcgaat
     3181 ccatacaggg atgccgcgtt tctccagttc atcaagaaag cgtaaagtat tatcgagttt
     3241 tacggccgtc aaacggggat gaagaccggc gtcgatcgtc ttgatatcta acagaaccag
     3301 atcgacctgt tcgagcacct ccaatgcttt accggaacag atatagccgg aagtgtccaa
     3361 cgccgtatga ataccgttct cacggcaaag gcggaaaaac tctttaagga attcaggttg
     3421 taacaaaggc tcgccaccgg tcacggtaac accaccttta gcgataaaat tcttatagcg
     3481 cagcacttcg gcaagcaacg cttcaggttc cagcagataa ggcgtttcac gctttacctc
     3541 ccaggtatcc ggattgtggc aatacagaca acgaagcgga catccctgca taaaaacgac
     3601 aaagcgaatt ccgggaccgt caacggtccc gaaactctct aaagaatgta tacgccccaa
     3661 catattaatc aatggacaat tataaactgc tgttgatggt gcgcgagatg acgtcaagct
     3721 gctgttcgcg tgtcagcttc acgaagttga cggcatagcc agaaacacgg atcgtaagct
     3781 gcgggtattt ctccgggtgc tccatcgcat cgaccaacag gtccttatcg aacacgttca
     3841 cattcagatg ctggccgccg tcaggcgtga aatagccatc caacaggctc accagattat
     3901 ttatctgaat atcgcgctcc ttacccaatg tagccggtga aacggcaaat gtataggaga
     3961 taccgtcatg cgcatgctgg aaaggcagtt tggcaacaga agccaaagcg gcgacagccc
     4021 ctttcgtgtc gcgtccgttc atcgggttgg ctcccggagc gaacggcgta ccacccggac
     4081 ggccgtcggg agtcgttccg gttttctttc cgtaaaccac gtttgatgtg atcgtcagga
     4141 tagattgtgt cggagttgcc ttgcggtatg tctgatgctg gcgcagatat tccatgaact
     4201 tctcggtaat gtcgacagca atactgtccg tgcggtcgtc attgtttccg aaaggtacat
     4261 attcgccttc gcgttcgaag tcgacagcca aaccacgttc gtcacggatc actttcactt
     4321 tcgtgtcacg gatggcagcc agcgagtcgg caacgataga aaggccggcg ataccggttg
     4381 cgcggatacg ttccacatct ccgtcatgaa gccccatctc gaatgcttca tacgcatatt
     4441 tgtcgtgcat gtagtgaatg atcttcagag cattgacata aacttttgcc aaccagcgca
     4501 tcatctgctc gtatttctcc atcacttcgt tgtaatccag atactcgctg gtgatcggtt
     4561 cgaaacgggg agccacctgc acacccgatt tctcgtcacg tccgccattg atcgcataca
     4621 acaagcactt tgccaggttg gcacgagctc cgaaatactg catctgctta ccgatcttca
     4681 tcggagacac acagcaggcg ataccgtaat cgtcgccata gtccggacgc atcagatcgt
     4741 cgttctcgta ctggatggca gaggtatcga tcgatacttt tgcgcagaag tttttccagt
     4801 tatccggagc attgttgaac caaagcaccg tcaggttggg ttcgggtgcc gggccgaggt
     4861 tatacaaggt atgcagataa cggtaagatg tctttgtcac cagcgaacgg ccgtcaacac
     4921 cttgtccgcc cagcgattca gtcacccaaa cagggtcgcc ggagaacagg tcgttgtatt
     4981 ccggagtacg caggaaacgg acaatacgca gtttgataat aaactggtcg atcaattcct
     5041 gtgcctcttc ttccgtcagc ttgccttcgc aaatatcttt ttcgatatag atatcgagga
     5101 aagtagaagt acgtccgaga gacatggctg ctccatcctg atcctttacg gctgccaggt
     5161 aagccagata caagaactgc acggcttcgc gggcatcctt tgccggacgt gtcacgtcga
     5221 aaccataacc ggcacacatt ctctcaaatg ctttcagcgc tttgatctgc tccgttatct
     5281 cctcacgact ctgaatgatt tcttctgtca gttcctgtat atcgagacgt ttctggaaac
     5341 gtttcttttc ttcgatcagg atctgggttc cgtacagagg tacacgacgg taatcaccga
     5401 tgatacgtcc gcgtccgtag gcatcaggca acccggtaat gatggcggaa cgacgtgccg
     5461 caatcatctc gtctgtatag gctgaaaaaa cgccttcgtt gtgcgtcttt ctgtatttgg
     5521 tgaagatttc ttttgtcatc gggtccagat gatagccata ggcttccaga ctgttttcga
     5581 ccatgcggat accgcctttc gggaagatac cgcgcttcaa cggggcgtct gtctgcaagc
     5641 cgacgattac ttcgttttcc ttatcgatgt aaccgggtcc gtatgtgtca atcccctggg
     5701 gaagcttcgt ttcggcatca tatactcctt tctccctttc aaccttaaac atctcggtta
     5761 gtttgttcca cactttcttc gttttctccg aagagggtac gaggaacgta tcgtctccgt
     5821 tataaggttt gtaattgttc tggataaagt ctcttacatt gatctccttt ttccaggttt
     5881 ctcctttgaa ctgcgcccag ttctcgtttt caaacttcat aagcttatct tgtctatttc
     5941 ggtttaggca cgcaaagata cgtcttttcc ccctatctga aaaggattgt aaaggacgag
     6001 ggatgttaaa ccggagaaaa tacctacaaa tagggataag ggaaataaaa acgaagcccc
     6061 ggcagtacga ataccgccgg ggcctgtttt ttgtctgccg tccggtcttc acagagggaa
     6121 aagcagtaga acttttaatt tcattacttt agtattatta atattaaatc caaccgctcg
     6181 ttcgcctgtc gcagggtaat tgaaaccgta gatcaagaaa acctcttaca tacggtttca
     6241 cgcaggttgt ctagaattat ttgattataa aatgtcattg tgcctgtgta agggtggttc
     6301 gctaaccacc cttacgatag acagtattgt tttttagtat caatcgttac ttaacgatag
     6361 cttttacagc agcttcgcct tcaacagcta caactactac acctgccgga gcagcgatag
     6421 ttgcgttgtc agaagaaacg acagtgttag ctactacctg acctaagatg ttgcagataa
     6481 caactttctt accggcagcg cctgcgattg ttacgttacc ttcgccagcg atcactttca
     6541 cttcagatgt tgcgatgcct tcgttggctg taggagcaga agttacttcg attacaaatg
     6601 cttcagcttc cttagcatct gtaccgtaaa ccaagttacc gttgattaca tatacatagt
     6661 taccattagc tttcagtaca tagtcaccgt cttcgttttc agtaactttg aacttgaagt
     6721 cttcgatatc cttgccagta tacttttcat cggcgataac caaagtgtct tcaccagaca
     6781 gacgttcagc gtctacaaat ttgatacgtt ctacactctt gtagtaaaga ttttcatcag
     6841 cagtaagttc tgcatattct ttcttgctga tttcatcatt agcataagcc ttatcaacaa
     6901 tttctttaaa cttcttagca gttgtcatca tcttgccagc gtaagaaatg aagaacttcg
     6961 gagttgcata accttcagca tttacagagt caacccacaa agcagctgtt tctttagcca
     7021 atactgcgtt gttattttcg tcagaagcga tgaagccaat gctattagta gcttcgaatg
     7081 tcatgtgctt gctgtcagca gccaaagaag gagcagcatc caagtctatg atttcgaacg
     7141 gagtagagtt agtaaagtca gttgtttctg ctactaattc ctcagaacca ttgattacac
     7201 cgtattcttt tacttcatca gcagtagcgc catatacgat agcgtatgta cctttaccat
     7261 tttctttcaa gaagaactcg atgtcatcct tagccatctt ccaagctgtt cccaaaccta
     7321 attcatcagc attgattgca tatgaataag ccagacgaac tgtatcagcc ggcaggatac
     7381 ctttttcttc attacctttg ccattcagtt caacccattt ttcaccgtca taatatttgt
     7441 agttggcagt aacagcctgt gctttttcgt tacggatcaa ttcccattca gaaccagcat
     7501 gaggaacaac agttacaaca tctccttcta caccagcttt caaatacaga tctgaaccgg
     7561 cttcttcgtt agcatattca cctgttgtta caaaggcgaa cttctgattg atgtcagaca
     7621 atgtactgta gtagccgttc agcttgtcat aatcttcaac tttcgtcaaa gtgattgttt
     7681 caagaccaga caaacctaaa tcagaagcaa atactgtgta agtattttca ccttctgctt
     7741 catatagacg gatattgtct tgtacaaaac ccggtttctg aacattgatc aacttaattg
     7801 tgttagcagc tgaacccgca gcaaccaacc actgcccctg tggctgatcg aagtcagctt
     7861 cagaaacttt atcataccaa cgtgcgccag tgaaatcatt cttcaacccc agtgcagaag
     7921 aattcttctt gtctgcaact ttggcagtta catttacgat caacattctt tcgttggcaa
     7981 cttcagtatt agcgacacgt gtacccttgc ctactgtaac ccccatgaaa gtagaatggc
     8041 agtcatattc gacagaagcc aactgacgag ttgtttcatc atttgtcact ttaccgaaag
     8101 tcacatcttt gttgtccagg tcaccaactt ttactttctg aactaatgca tatttaccat
     8161 ctccgatgtt tgtttcgttc tcttcagcat agaatacagt gttcttgtcg tcaattttct
     8221 tgtctttaat cgctttagca gtcatttttg catagcgata accgattgcg ttggcagcca
     8281 actctgagtt ggaaacacgt tcgtttgcta aaactacata ttcatcgtct tttgtatctt
     8341 ttgtgccttt gttgtcaacc aacttgaaac ccaaattatc attggcgatt ttttctacgc
     8401 ttacattttc aaacacatcc atgtcatcca atgtttccgg gaactcgatt gtgaagtttt
     8461 cgccaaactt gctcgcaaaa gcttctgctg taatttggtc gttgtagatt tcgtagagag
     8521 ctaccttctt cttgataacg gaagtagatc catccgtatg atgctcagaa ctttgtaata
     8581 aagccaatga ccaatctgct gtgccatcgt tcttcagtcc taaaaaatac ggttcttttt
     8641 catcagaaag cacagcttgc aaattgccgt ttgctgcaac agtaaaccaa cgaaacgact
     8701 ttgtttcatc gtttgcctct tttttggcag ctaaagcata agctccatct ttcttttcaa
     8761 aagccagata ctgttctcct tcaatatttt tgaaagcata atgtgtaaca gttccaacct
     8821 ttttagtttc aacagtccat tgtgcagcag caacaggatt tgcagccgta atatcagcac
     8881 cattcactaa tccttgcaaa gaaaaagcct gcaagtaatc tgtcggactc acaaaatgca
     8941 cccctgccaa ataataagcg cggcttgctt gtgcatcctt ccattcaaca ttacgcccct
     9001 ccaactgtgc gaaagctgaa ctaaaagaac cggctaccaa agcggcagcc aaaagagtag
     9061 aaaatctctt gttcataatc taaaatgttt aattaataat aatatgtata ttgaatatcg
     9121 ttcttacttc ctgtttaaca ggtttttacc aaattcctgt attttgacga gagaaaacgt
     9181 acgttttttt tagtcatttt tgaggggctt tctggagggt ttgtgttgga aagctggttt
     9241 ttcgtacttg ttaagctatc tgattgataa gaaagaatat agaaaaggaa aaataattgg
     9301 aagaaaggat tgcaggttca aaaagtagtt gtatttttgt gcagtgaaaa tggcgaaaga
     9361 aaacgtacgt tttttcgcta tttttcttct tatacccata tacttcttat tagcaatgac
     9421 ttacattgaa aaaagtgcct aaagccatat aaaaaaagag ctgttttcaa ccgctcgcca
     9481 aactttttta catcttcatc aaaacaaaga taatcaatca cctataagat taactccctt
     9541 tattcacatt ggaggggaaa aacggcaaaa acagcaggtt tcgtaatttc atcttggaaa
     9601 agctccccct tctgttaaag atatacaaaa tacggagtat tggttgctta gctcaataac
     9661 agcttcaaga cttgcaaaac cttacattat tatgtatctt tacatcaacg tccgtcacag
     9721 acggatcaaa caactataat acattaatgg aatatatgaa agaaaaaatc gactcctccg
     9781 acatccccac ctcctatctg ctctgcatga aacaagattg ccccaaagcc actacttgct
     9841 tgaggagaat cgcagaacaa cagatcggcg acgaagtcaa actgtggcac gtcatcagcc
     9901 ctaaatacca agagaagcaa accgaccgat gtgcttattt ccgccctgcc gataaactga
     9961 cctatgcgct cggtttcatc gggatgctgg accggatgcc ctacaaactg atgcaggaag
    10021 ccatttgcaa gctgatgaga cggttcggac gcaggactta ctaccgcgtg cgaaaaggcg
    10081 aacgcccgct ctcgccggac gaacaaaaaa gcatgttgaa catactgaaa cagtgcggta
    10141 tcaacgatcc cggaaagttc gatgcctact tcgaggcata cgactggtaa gttcacatga
    10201 cgctacttgc ctacgtattg gttgtgccat acctatgtaa cgaccgtttc ctcggcatga
    10261 aacggttgtg ccaagcttat gtaacaggcg tttcctactc aggaaacagt tgtgccaagc
    10321 cgatgtaatt gttttggcac agccggagca gcaaacatac ccttgcggga acaagtccaa
    10381 gactcgacgc cgaacagatt ccggacagaa gcgaatggga aacggaaaca taaaaaagaa
    10441 gcctctcttc acagagaggc ttctttttta taccgaaaat aaccaataaa aacttttcga
    10501 tatagttaat catcttatat gcttacataa ttgacaaaag gttttgatat agcgattata
    10561 ctaatagtgt tactttctta atgacattgc aaagatacgg gtacttccca cctcctacaa
    10621 tacctatatg tgagtaaaaa aacgtctttt actacctaat caaggtgata ttcaggcgca
    10681 atacctacaa atgggtaaca tcggaacctt tttacctact aattgcgatt gcacaccgtt
    10741 gacagcccct ctaattttgc caaaaattaa aaaacgcaat gaaaaggtta actaatttat
    10801 tagcaatcac tctactcacc tcttgtgtaa cggcatttgc acaggaacaa gaagaaacaa
    10861 cgacagaaaa atccgcagtg gaacaatccg cagacattta tgcagccgga tataacaagt
    10921 tccgcttcgg cggatatggg gagatcctcg caaactttat ggactacggc atcaaccgtt
    10981 tccggggtac ggacaacgga agcaagaaag accatcgcaa ttcgatctcc ataccccgtt
    11041 ttgtcttggc cttcgattac aaattcaatt cccaatgggt attaggagca gaaatagaat
    11101 ttgaggctgg aggtacggga agtgcctatg agatagaaaa cacagaaaac ggagaatacg
    11161 aaatggaagt tgaaaaaggc ggtgaagttg ctttggaaca attccacatc acacgtctta
    11221 tccatccggc cttcaatgtc cgtgccggtc atttgatcgt cccggtcggt ttgaccaacg
    11281 agcatcacga gccgatcaac ttcttcggaa cttctcgtcc ggaaggcgaa acgaccatcc
    11341 ttccttctac ctggcacgaa aacggtatcg aagtgttcgg tacgttcggc cgaggctaca
    11401 cacgtttcaa ctaccaggct ttggtcgttg ccggattgaa cgccaacggg ttcgaccgca
    11461 atacatgggt tgccggcggc aagcagggac tattcgaaac agacaacttc acctcaccgg
    11521 gctatgtggc ccgcctgaac tatttaggag taccgggatt gaaaataggc ggttccttct
    11581 actattgcca caatacggga gccaattccg acaaaccgga aacatacgtc aaatatggaa
    11641 acataccttt gcgcatctat acggctgacc tgcaatacaa aaacaaatat gtcaccgcac
    11701 gcgcaaacat gatatacggc aacctgagca aagccgacga cctcagcagt gtcaacaacc
    11761 accaaagcgg cggttctcct tatacacaga caaccccgat cgccaaacgt gcggtcagct
    11821 acggtggtga agtggggttc aacctgcgtg cggtttgtaa agacaatatg agcgtacccg
    11881 taatctatcc gttcgtccgc tacgaatact acaacccaca ggaaaaaggc gaaggcaagc
    11941 acacgatgga tttacgcaac aaagtaagca tgtggacagc cggagccaat tggtatgctt
    12001 tacctaatct tgtcgtgaaa gcagactata caacacgcaa aatcggaggc ggcaaatata
    12061 acagcgaaaa cgaattcagc ttggctatcg cctatatcgg ctggttcctc agcaaataaa
    12121 aacaatataa acaaattaat aacttatcaa taaaaatgaa aaagaaaaat tatttctatc
    12181 tggcagcctt atcgctcgcc atgacattct cgatgggagc atgtagcgac aacaacgacc
    12241 ccaatccgga tggtggcgga aaagatccgg tcaacctgga ttacagttct gaaaacgcca
    12301 gtgcatgggg taactatatg tataacgttg caatgttgct gaacgacgat gcaaccatgc
    12361 tctacaattc ttgggtaacc gactacgtcg atgagcaggg ttcacacggc ccatatgcca
    12421 cgattttcaa agaccagact gccggagctt accaaagccc gctctcgtgt atcgaggaaa
    12481 tgatcgaaag cggtatgtgg aacatcgcca acgaagtagg tgacgccaag atcaaggacc
    12541 cgtataccaa atataccagc ggtgacaagg aaggcggtct ctatgccgtc gaatcatggt
    12601 atagctggca ttcgcgcgac gactatacga acaatatctt ctccatccgt aacacatact
    12661 acggccgcat cgacgacaac gacgtgtcca aagtagacgg aaacctgagt gcattcaact
    12721 cttacaaaga tttcgacgat gaaggagaca tcgcagaaca ctcgctttca aaactgatcg
    12781 cttcaaccaa cccggctctc gacgaagaaa tcaaaacgct gattttcgct tctgcaaagg
    12841 cgatccaggc tattccgcaa ccgttccgca acaacatcga cagcgaagag tccgttgccg
    12901 caatgaacac ttgcatggaa ctggccaacc tgttgttaaa tgaagtaaaa ccgtatgtaa
    12961 accaaacatt cggcgatcct gaatacgacg atgaccttga tgcaatagcc gaacagtttg
    13021 tcgatgcggt cgttcttcct acttataaag acttgcagga aaagaacaag cttttgctgg
    13081 atgcggtaaa ccagttcaga caaaacccaa gcaacgacaa cttcgaaaag gcctgcaatt
    13141 tatggatcac ggcacgcgaa ccgtgggaaa agagcgaagc tttccttatc ggtccggtcg
    13201 ccaacttagg tctggacccc aacatggaca gctggccttt ggaccagaac ggtatcgtac
    13261 aggtattgaa ttcacaaaac tgggatgacc tggaatggag cggaaacttt gacgaagaag
    13321 atgaagccat cggagccgca cagagcgtac gtggttacca tacattggaa tatctcctat
    13381 tcaaagacgg gcagccccgc actgtcgatg gagcaaaata aacatgcctc tgagacataa
    13441 aacttgataa tagatcatga caaaccttga aacagcagac aaatgcccgc tgtttcaggg
    13501 tttcagagta attacacaat gcgactcgcg ttattcggaa ataaattcag aaaaccaata
    13561 aaatgatatg aagcaatctt acctgttaac atcctcgcta ttcctgctct ttgcatgcgc
    13621 agcttgtgaa gaggacgata aaatggatat ggataaaata gatgtcccga acggatatgc
    13681 gctgtcagca gggacttcaa cgattttcct aaactcatcg gtcgcctacg atacgaacgc
    13741 cgactggata acaggagcca actcgatccg tttcaacaac ggcgacggtc tctacgacga
    13801 tgtacgcacc agcaacaatg gcgacggagg cggtctcgga cctgtttatg ccggctattc
    13861 ctgcggcagt tgccatcgca acgcaggaag gaccaaaccg acattgtggg aaaatggcgg
    13921 atcgggcaac tacggtttct cttccatgct ggtctatatc tcccgccgca acggtgcttt
    13981 cttccgcgac tacggacgtg tattgcacga ccaagccatc tacggcgtca aaccggaagg
    14041 taagttgtcc gtcacatacg acaagcagac tttttccttc cccgacggag agacttacga
    14101 actatgcaaa cccaattaca cgataaccga atggtataaa gacagtatcg ccccggaaga
    14161 tttgttctgc accgtacgca tcccgttacg ccacgtcggt atgggacaga tgatggcaat
    14221 cgaccgcagg gaaatcgaag cgctcgctgc caaaagcaat tatccggaat atggtatcag
    14281 cggacgttgc aactatatca ccgagaaggg tgtcaccggt gtcggccttt caggaaacaa
    14341 ggcacagcat cttgacctga ccgtcgaact gggcttttca agcgatatgg gcgtgacaaa
    14401 cagccgctat ccggaagaga tttgcgaagg gcaggctcag atcaaccaag gcagcatgat
    14461 gggactctcg tacgaccagc tcgacatatc gaccgccgat atggaagatg tggaccttta
    14521 catgcaaagc ctcggcgtac cggcacggcg caacataaac gaccctcagg tcatcttagg
    14581 agaacaaaag ttttacgaag cgaaatgcca tctctgccac gtcactacgc tgcacacgca
    14641 agcgggcggt tccacactgc tcaacggcac acgtttgcca tggctcggcg gacagaccat
    14701 acatccttat tctgatttcc tactgcatga catggggtcg gagatcatgg gagtcgggtt
    14761 gaacgacaat tatgtcagcg gcctggcacg aggaaacgaa tggcgtacta cgccgctttg
    14821 gggtatcggg ctgcaggaga aagtcaacgg tcatacctat ttccttcatg acggacgcgc
    14881 ccgcaacctg accgaagcca tcatgtggca tggaggcgaa ggggaagcct ccaaaaattt
    14941 attcaaacaa atgagcaagg aagagcgtga ggcagtgatc gcattcctca actccttata
    15001 atttatccat aagacaaact aaaatgaaac aactgataat cacaattgca gcattattac
    15061 tattgccgtt ggccgtcatg gcccaatatg aggaagatac ggaaaacggt gtcgtatcac
    15121 taaacggcaa agaaggtttt acaatcgcta ccaagaaggg ggatttcgtt ttcaaacctt
    15181 atatgttggt acagaccagt gctaacatca actactacga cgatgaaggg ctggacccgg
    15241 cctacaatca ggacaatata cacaacagcg gtttctcgat cccttatgcc atcctcggtt
    15301 tcacgggcaa ggcattcgac cgggtgacat tcaacctctc catcaatgct gccggaaacg
    15361 gaggaaacat ccttcaacag gcttggttcg acgtagagat aaaaaagagt tttgccatac
    15421 gtgttggcaa gttcaagact ccgttctcgc acgcttacct gactacgctg ggcgagacgt
    15481 taatgccgac actgccgaca tcgctcacct catccgttat cctgccttat tctcttaatg
    15541 ccgtgacacc gaacatcggc atgggattcg acctcggagt ggaagtgcac ggattggtaa
    15601 aggataagtt cggctacgaa gttgggattt tcaacggaac gggaagctcc gtcaacgtgg
    15661 catccaaaac gttcagcgac gactggcata tcccgtcatt gttgtatgcc ggccgcatca
    15721 cgtacatgcc gaaaggagtt atgccgtcca accagggcag cccgaaccgt ttgaaggaag
    15781 ataagatgct gttcggtctt tccacttcat tgaatgtgga gagcgaaagc gaaagtacga
    15841 acgatttccg ggcaggagca gaattcgcca tgttgaagaa tcgcctgtat ctcggcgctg
    15901 aaatctatta tatgaatgta
//
