LOCUS       c00076_gnlPro..        14793 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LEGJGCIE_76.
ACCESSION   c00076_gnlPro..
VERSION     c00076_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 23:53:04
            Original ID  :: gnl|Prokka|LEGJGCIE_76
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14793
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14793
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1353:4793]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1354..4793
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14793
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14793
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(141..1094)
                     /locus_tag="ctg76_1"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSEISCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPAPGVDSVYKRSGFIHPLKTLRGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             1354..2028
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_2"
                     /sec_met_domain="SucD_FumR (E-value: 1.4e-67, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             2067..4010
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.5e-60, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.3e-38,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             4038..4793
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_4"
                     /sec_met_domain="Fer2_3 (E-value: 1.4e-26, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 4.2e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.5e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             4804..4989
                     /locus_tag="ctg76_5"
                     /transl_table=11
                     /translation="MYVYGKARRQWQRAFFMFVQTHKKAALPIIKVDAAFLLLSSETVS
                     RFPLCKDFVNLRSKIL"
     CDS             4986..5144
                     /locus_tag="ctg76_6"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(5117..6148)
                     /locus_tag="ctg76_7"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLDILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETMEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             6308..6664
                     /locus_tag="ctg76_8"
                     /transl_table=11
                     /translation="MVRLTSKEEEILGYFWAKGPLFVRELLDLQEESKPHYNTLSTIVR
                     SLEEKGYIGYKVYGNTHQYYALVSEDEYRRNSLKQVISKYYDNSYTRVVSTLIEEEVLT
                     IDELQKLIQQIKNK"
     CDS             6678..7310
                     /locus_tag="ctg76_9"
                     /transl_table=11
                     /translation="MDAFLLYILKSGICLTVFYVCFKALFSNDTFFRFNRWILLVGTGV
                     CMLLPLCRIQTARPFPLSRPVSQLEIVFYEEEMKAFPVPESKEEITIPTEQRNISVPWT
                     GIIGIAFLTGSGICLTTTILSFGKMYQLTRKNRKLKQGKYTLILTPDPVSPFSWGRYIF
                     LSENDYRNHPNEILMHEKMHLRYNHSVDLIYMKRFFFCNGLILPYGY"
     CDS             7478..8446
                     /locus_tag="ctg76_10"
                     /transl_table=11
                     /translation="MMLKKKSNNWARLKLALLVPVGFAALSAFARPETSPPPAATMTDN
                     IHLSINKSTVNQETMQQDHAVFLTYKESGSEDLNSIVCKTLDRIRTRVAEGQFKNALEV
                     TVNPAFDDIPASYLETVKDVLEERDIKCKIDMTVPNTIMDDVAKPYRKYDDVVYLIQNK
                     KIVAALSISKFSANQNDPRLDKISKSASLILQPENPKVSRQEMEKLKNLLDKKGLTSEI
                     NMNIFKIGDAAAPPPPPPAGQVIFSYRDGQPDQQFVLYDRHAKPGANLGQRIDKIYKDN
                     ITKVSIKINKSTPKDLLETVKQELKKKINYPVQYEILQFVD"
     CDS             8558..9793
                     /locus_tag="ctg76_11"
                     /transl_table=11
                     /translation="MIHNVKILFFICFFTACSSTEQKEIVTAGELLRQAAFYGERLQFL
                     PALETYQQAIKLAEKEKDSTVFSLAYLEMGKIYRYQSLKQKALQSEKKALSYIKSPACD
                     SLRLELYREIGDMYTLSGQADSAFHYYEMAGCRIKQAKILQQNGSNKEAETLLKTELEQ
                     TIFPKEKAEVCLALADLQITLGKLDEAEKSLSQVPPSHPHLYAALSRIAQSRGDSLQAD
                     FYHKSYLHHLSVLRQEKEQNQITQLLRTSEQKEWEKRLTDSQKAQKEQIYVWVTLLVSC
                     STGIWGYSRYRQKRNVVSLSETDFFSSEIYLRFHRKEEWKPVPKDWEELLQAFNRTYPD
                     FRERLKRKIPKLSEQEWRMCCLIKMEVPPSTAAMLLCCTNQAISMRRVRLYQKITGEKG
                     TPELCDSFIRDF"
     CDS             9860..11056
                     /locus_tag="ctg76_12"
                     /transl_table=11
                     /translation="MKKMLFGLMTAIATFTGCESKQPAGELPRIDLTATSFAFDQVEIA
                     DEIESIEYVPLELTDESLIADVLDLCVSDEYIFVYSTRQDGVLQFDRKGKYLRCIAKTG
                     NGPGETGQIISLTVDEENRLFCVSEYFSTSFYSFDGEFIKKIENPRPYSYQFSVGPNTM
                     AELGRMYVPMNTPGMFSLGVFNWGTDDTIAFRHTIGDMDLMPLEETSLKGWIFSGSKDG
                     ILCYSEGIDTVWDVNARNIAPAFLINTGYSVEEEKEMRSSKTGNEAVDGKYSVFSFFET
                     PRHYFVKCFEGSNQSKFYLYGLDKATGELKRETSPLNAQELFKNNWTLAGIGFRNTKDN
                     GLPIWPYLSYPGKKQMVQFNTAVEIEYLKEKYPDLKKHLVLQQITEDSNPLITIYHLR"
     CDS             11135..12370
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_13"
                     /sec_met_domain="Peptidase_U32 (E-value: 1.9e-69, bitscore:
                     223.7, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNNFTTDDLRK
                     IVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAMNYANSIGQ
                     EVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITGPKGELIRI
                     EMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIELDIENQYIM
                     SPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNGTFDEKKVA
                     AWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDKIGVAEFEM
                     ESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEKIRPSDRLY
                     KMEKVQLEKVFE"
     CDS             12370..12777
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_14"
                     /sec_met_domain="HBT (E-value: 1.2e-08, bitscore: 25.6,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 1.8e-09, bitscore: 28.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNAYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             12774..13889
                     /locus_tag="ctg76_15"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYF
                     KGNTNLDATRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRVGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAGATPVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVL
                     EIPVHQLSMLLFELEINGKVKALPGNLYKLS"
ORIGIN
        1 agttttatta agagtttctc attgatttgt agctgtattt acataaaaga gccttggctt
       61 tgatgatata ggagaacaag ccctttttcc ttttcttgtt taccttgccc tgcaaattgt
      121 cagtttgttt tagtagaaat tcaatcacgt tcgaaatcgg acagcacttc tgccgtagta
      181 gcgttgatgt tcttgtccaa tacataaatg cggtaagaca ggctcagttc tttaccgggt
      241 tccaatgtga atgccttctg cttggtcggt gagaaattcc acatgacgtc accggcaggc
      301 ttgttgactg ttttgtccca tacgcgtaaa ggctcaggat agttcaggtt ggaaggggag
      361 gcaacgatta ggatacaggc cttttcgttt ccggctttcc cttggtagta gcaccaacgg
      421 gctctcgaac cgtcagcttc gtcgcgggaa aggccttccg aggtgagcat ttcggctgtc
      481 tgatcgttcc agtcttcgcg cgtacggatg catatgccgc cataacggta agcttccatg
      541 gtgatcgggc tggggctggc gaggcggata gtggtatgat agtcgatgta ataacctggt
      601 aaggatgttg tcccgatgtt gatctccagg cgttcgttca ttgctacttt ttctgcggga
      661 gaatcggggt agaccacatg gtccagtgtc gcaacaaaac cgttgtcgga tacgtgttcg
      721 aagttgcgga agcgaactgt tccttgtttt ttgtggagat tccagaaatc gatctcgttt
      781 ccttcgaacg tggttttcgt ccaggcatac cacaaaccga aatgatggta atggtcggcg
      841 ggagaacaat tggtcatcac ttcgcctctc aatgtcttca aaggatggat gaaaccgctg
      901 cgtttataga ccgagtcaac gccaggggct gggtaaaccg tggtatagtt gtaagagaac
      961 aacagtttat ctcctatctt atagtctaag gttttccccg tgtcgacgac ggaacaggat
     1021 atttcggaag gctgacaaga gcctaagaac agagaaatca aaaaaacacc aatagaaaaa
     1081 atagcagttt tcataatatg acaattaaat aataatcagt tatccggcaa gaccttgcct
     1141 gtatcggcta caaaaaaacg aaattttttc gtttcgcaca atccgtttgt gatatctgat
     1201 gcaaataaaa ccagccagca agcagcgttc taattgatga aatatttctt taatcgtttg
     1261 cgtgatatgg ggatttagca tacctttgca cgataataac catagattgg aggaaatttc
     1321 taaatacaat taaataactt aaattattat cttatgtggt tacttaattc ttctatcggg
     1381 aagaagctga taatgagtat atcaggtctt tttctcattc tgttcttggt gttccactta
     1441 tgtatgaaca ttgcggcagt attttctggt gaagcgtata acgtgatttg cggtttgctg
     1501 ggttctaact ggtatgcttt gctcggtaca ttggtgttgg ctgcaggtgt agtcgtgcac
     1561 ttcgtgtatg ctattatctt gactctgcag aatcgtaagg ctcgcggtaa cgaccgttat
     1621 gccatcaacg ctcgtccgaa aggtgttgaa tgggcttctc agaacatgtt tgttttgggt
     1681 gtgatcgtta tcctgttcat ggttctgcac tttactcagt tctggtacaa catgatgttt
     1741 gccgaactgg caggtattca tggtgacatt catccgcagg atggtgcagc gtttatcaat
     1801 ttctacttcc agggcaatgt tgtgaatacg gtgttgtatc tgatttggtt cgttgctctg
     1861 tggtttcacc tgactcacgg tttctggtct gcgattcaca caattggctg gaacaatacc
     1921 gtttggttaa gccgttggga atgtatctct aaatgggttg ccactattat ttgtggctta
     1981 ttcgctgtta tcacagttat cttctacctg aacggtgtag gtgcttaatt tcggatatta
     2041 ttttttcaat ttgaaaataa aacattatga ctcaaataga ttctaaaatt cctcaaggcc
     2101 cgttggctga gaagtggaca aattataaaa atcaccagaa attggtgaat cccgcaaaca
     2161 aacgtcgttt ggacataatt gtagtaggta ctggtctggc gggtgcttct gctgctgcct
     2221 ctctggctga aatgggattc aatgtattga atttctgtat tcaggactct ccccgtcgtg
     2281 cgcactctat cgctgcacag ggcggtatca atgcggcaaa gaattatcag aatgatggtg
     2341 actcggttta tcgtctgttc tacgatacaa tcaaaggtgg tgactaccgt gcccgcgaag
     2401 caaacgtcta tcgtctggct gaagtgtcaa actctattat cgaccagtgc gtagcacagg
     2461 gtgtaccatt cgctcgcgaa tatggcggtc tgttggataa ccgttcattc gggggtgctc
     2521 aggtatcccg tacgttctat gcccgtggtc agaccggaca gcagctgctg ttgggtgctt
     2581 actctgcatt gagccgtcag attggtttgg gaaaggtgaa gatgtacaca cgccatgaaa
     2641 tgctggatgt tgtgaaggtt gacggacgtg ctcgcggtat tattgcccgt aatttgatta
     2701 ccggtaagat cgaacgtttt gccgctcacg cagtcgttgt tgcgacaggt ggttatgtaa
     2761 atacattctt cttgtctact aacgcgatgg cgtctaacgg ttctgctgca tggcagtgct
     2821 acaagaaagg ggcttacttt gctaatcctt gtatggtgca gatccacccg acttgtgtgc
     2881 cggtgaaagg tgacttccag tctaagctga ctttgatgtc agaatcactg cgtaacgatg
     2941 gtcgcatctg ggttccgaag aagctggaag atgcgaaggc attgcaggcc ggaacaaaaa
     3001 agggaaagga tattcctgaa gcagatcgcg actactatct ggaacgtcgt tatccggcat
     3061 tcggtaactt ggttcctcgt gatgtggctt cacgtgccgc taaagaacgt tgtgatgccg
     3121 gtttcggtgt aaatagcacg ggcttggcgg tattcctgga tttctccgac gctatcaacc
     3181 gtctgggtaa ggaagtggtt aaacagaaat atggtaacct gttcgatatg tacgaagaga
     3241 tcacgaacga tgatccgtat gaaactccga tgatgattta tcctgcattg cactactcaa
     3301 tgggtggttt gtgggtagac tatgaattga tgacttctat tccggggctg ttcgcaatcg
     3361 gtgaagccaa cttctctgac cacggcgcta accgtctggg tgcttctgct ttgatgcagg
     3421 gattggctga tggttacttt gtattgcctt acacgatcca gaactatctg tctgaccaga
     3481 tccaggttcc gcgcttcagc actgacctgc ctgaatttgt ggaagcagaa aaggctatta
     3541 acgctcgtat cgcgaagttg atgaacgtga agggtaaaga aacagtcgat tctatccacc
     3601 gtaagctggg acatatcatg tgggaacacg tcggtatggc acgcgacgcg gaaggtttga
     3661 aagaggctat ccagatgttg aaagacctga agaaggaatt ctggagcaat gtattcattc
     3721 cgggtgaggc caatagcttg aacgtggaat tggacaaggc attgcgtttg gctgacttta
     3781 tcgaaatcgg tgcattgatg gcacacgatg cgttagaccg cgcagaatct tgtggtggcc
     3841 acttccgtac ggaacatcag accgaagaag gcgaagctat gcgtcatgac gataagttca
     3901 tgtacgtctc ttgttgggaa taccagggtg aagacaaaga cccggttatg ctgaaggaag
     3961 atttgaacta tcagttcgtt gttcctcaaa cacgtaacta caagaagtaa taatcatcaa
     4021 tcacaaaaat tagaatcatg gataaagata taaaggtaac acttaaagtt tggcgtcaga
     4081 aaggtccgaa agataaagga cagtttgaga cttaccaaat cgacaaaatc aatcagagtg
     4141 tttctttctt ggaaatgtta gacattttga atgaacgttt ggttagcgaa ggcaaagaac
     4201 ctatcgtatt cgaccacgac tgccgtgaag gtatctgcgg tatgtgttca ttgtatgtaa
     4261 acggacatcc gcacggaccg gcaacaggtg caacaacctg tcagctctat atgcgccgtt
     4321 tcaatgatgg tgagacgatt acgatcgagc cgtggcgttc tgctggtttc ccggtaatcc
     4381 gcgacttgat ggtagaccgt tatgcttatg ataagattat ccaggcaggt ggtttcgttt
     4441 ctgtaaacac aggtggggtt cctgatgcta atgcaattcc tatttctaag gctgatgcgg
     4501 atttggctat ggatgctgct gcttgtatcg gctgcggtgc ttgtgctgct gcttgtaaga
     4561 acggttcagc tatgctgttc gtctctgcaa aggttagcca gctggctctt ttgcctcagg
     4621 gtaaggtgga agctgctcgt cgtgcaaaag caatggttgc taagatggat gaactgggct
     4681 ttggtaactg tacgaacact cgcgcttgcg aaatggaatg tccgaagaac atctccgtta
     4741 gcaacatcgc tcgcttgaac cgcgagttca tctctgctaa gttacaagac taatacatta
     4801 tatatgtatg tatatggaaa agcccgtcgc caatggcaac gggctttctt tatgttcgtt
     4861 caaacccaca aaaaagccgc actccctata ataaaagtgg atgcggcttt tttgttgctt
     4921 tccagtgaaa cagtctctcg attccctctc tgcaaagact ttgttaacct tagatctaaa
     4981 atactatgaa aaaaactcac tgcaaatata aagtatattt actgaatacg caagagtttg
     5041 taattacatt ttattgcaaa tttgctactt tttgttttaa aattgacact gtgtgcggat
     5101 tcacactgtt attatatcaa caatcgatcg attctgacac ttgagagtcg ctttgaaatc
     5161 cgtatcctgt atgaaatttg tcggggatgg aatccagaat gtcgaataat gcttccattg
     5221 tttccgcacg tagcatggcg acgcgtgtct gcttgaagtc tgcaatacct ttaaacagcg
     5281 gagttgcagc caaatggcgg cgaatgtgga gaattccccg gcgctcatcc aaacgttcca
     5341 cgctttgttc cacctgcttt ttcagtatgt ccagatacca tgaaaaagat tcggcaggca
     5401 atgtctcgcc tgtatccaga taatgcctca cttctctgaa aatccagggg cggcctatgc
     5461 tgccccggcc aatcataacg gcatccacgc catattgttc gaaacgttgt ttgcagattt
     5521 cggcggaagt cacatcgcca ttgccgatga tgggaatttg tatacgggga ttgtttttta
     5581 cttcaccgat cagtgtccag tctgcctctc ctgtgtacat ctgtgcccgg gtacgtccgt
     5641 ggatggaaag ggctgcgata ccgcaatcct gtagctgttc ggccaagtct acgatgatcc
     5701 ggttgtcggc atcccagccc aagcgggttt ttacggtgac agggatgttc accgctttga
     5761 cgacttcacg ggtgatgtcc agcatcagtg gaatattgcg cagcatgccg gcgcctgctc
     5821 ctttgcctgc cactcgtttg acagggcaac cgaaattgat atcgagaatg tccggatgag
     5881 cggcttcgca aatttgcgcg gcttcgacca ttgtcggaac atcacggcca tatatttgta
     5941 tggcgaccgg acgttcttca tccgccacat tcagcttttg ctgtgtttta tttacactgc
     6001 ggattagggc gtctgctgaa acgaattcgg tataaaccat atcggcacca aaacgtttgc
     6061 acatcaaccg gaaagaaata tctgtaacgt cttccatcgg agctaagaag acggggcgtt
     6121 cgcctaaatc tattgtacct attttcatat ttatattatc aatgacgggg acaaaggtac
     6181 tgatttcctg ctaaaaacag ggataaaagg atatctacta aaaaatatag taaaataact
     6241 atatgatata gttgtgttac taaataatat agttgtattt gtgcattcct ctaacaaaaa
     6301 acggattatg gttagattaa catcaaaaga agaagaaata ttgggctact tttgggcgaa
     6361 aggccccctg ttcgttcgcg aactactcga cttacaggaa gaatctaagc cgcattataa
     6421 caccttgtcc acgattgtcc gctcattgga agaaaaagga tatatcggat acaaggtata
     6481 cggtaatacg caccaatact atgcactggt atcggaagac gaataccggc gtaattcctt
     6541 gaaacaggtg atcagcaaat attatgacaa ctcgtacacc cgtgtcgttt cgacgctgat
     6601 agaagaagag gtgctcacga tcgacgagtt acagaagctg atccagcaga taaaaaacaa
     6661 ataaaaaacc aacgcttatg gacgcttttc ttctatacat attaaaatct ggtatttgcc
     6721 tgacagtctt ttatgtctgt ttcaaggcat tattcagtaa cgacacgttt ttccggttca
     6781 accgctggat attactggta gggacaggag tttgcatgtt gctgccactt tgccggatcc
     6841 aaacagcccg gccttttcct cttagccggc cagtcagcca actggagata gttttctatg
     6901 aagaagagat gaaagcgttt cctgttccgg aaagcaaaga agaaattacg attccgacag
     6961 agcagagaaa tatatctgtt ccctggacgg gaattatcgg gattgctttt ctaacaggca
     7021 gtggtatctg cctgaccaca acgattctgt cattcggaaa aatgtatcaa ctaacaagaa
     7081 aaaacaggaa actaaaacag gggaaataca cgttaatcct gactcccgat cccgtatccc
     7141 ctttcagttg gggacgttat atattccttt cggaaaacga ttaccggaac catccgaacg
     7201 aaatcctcat gcacgaaaaa atgcacctcc gctataacca ttcggtcgat ctgatctata
     7261 tgaaacgatt cttcttctgc aatggtttaa tcctgccgta tggttattaa aaagggaatt
     7321 acggggcata cacgaatacc aggcggataa aggcgtactc agtcaaggca tcgatgcaac
     7381 aaaatatcaa ctattactcg tgaaaaaagc tgtcggctcc agcctctaca ctcttgccaa
     7441 cagcttcaat cacagtaaaa ttaaaaaacg tattactatg atgttaaaaa agaaatcaaa
     7501 caattgggcc cggttgaagc ttgcgctcct ggtcccggta ggcttcgcgg ccttaagtgc
     7561 attcgcccgt ccggaaacaa gtccgccgcc ggcagcgaca atgaccgaca acattcatct
     7621 atcgattaac aaaagtacgg taaatcagga aacgatgcaa caggatcatg cagttttcct
     7681 cacctacaaa gaatcgggtt cggaggatct gaacagtatt gtatgcaaaa ctctggacag
     7741 aatcagaaca cgagtagcgg agggacaatt caagaacgcc ctggaagtta ctgttaatcc
     7801 ggccttcgac gatatcccgg cttcttatct ggaaacagta aaagatgttt tggaagaaag
     7861 agatattaaa tgcaagatcg acatgactgt tccgaatact atcatggatg atgttgccaa
     7921 accttaccgc aaatatgacg atgtggttta tctgattcag aataaaaaga ttgtcgcagc
     7981 actaagcatc agtaagttta gtgcaaacca gaatgatccg aggctggata agatatccaa
     8041 atcagcttcc ttaattctcc aacctgaaaa tccgaaagta tccagacaag aaatggagaa
     8101 attaaaaaac ttgttggaca aaaaaggatt gacaagcgaa atcaacatga atattttcaa
     8161 gatcggagat gctgcggctc cacctccccc acctcctgcc ggacaggtta ttttcagtta
     8221 ccgggacggg cagccggacc aacagttcgt tttatacgat cgccatgcca aaccgggagc
     8281 caatctcgga caacgcatag acaagattta caaggacaat attacgaaag taagtataaa
     8341 gattaacaaa agtactccca aagacctgtt ggaaacggtt aagcaagaac tgaaaaagaa
     8401 aatcaattac cctgtccaat acgagatcct gcaattcgtc gattaaaatc agaaacacgg
     8461 attatctatt tatcatcctc tccgtttaca aaacctgctc cagggggtaa acggagagga
     8521 atattattat ctttactcct tcaaaagaag gattcagatg atacacaatg taaagatact
     8581 ctttttcatt tgctttttca ccgcctgttc ttctaccgaa caaaaagaga ttgtcaccgc
     8641 cggagagctc cttcgacagg ctgctttcta tggggaaaga ttgcaatttc ttccggcatt
     8701 ggaaacctat caacaggcaa tcaaattggc ggagaaggag aaagacagca ccgtcttttc
     8761 ccttgcctac ctggaaatgg gaaaaatcta tcggtatcaa tctttaaaac aaaaggcact
     8821 acaaagtgag aaaaaagcat taagctatat caaaagtcct gcctgcgatt cgctacggct
     8881 ggaactttac cgggaaatag gggatatgta taccttgtcc ggacaagcag acagtgcctt
     8941 tcactattat gaaatggctg gatgtcggat aaaacaggca aagatattgc aacagaatgg
     9001 aagcaataaa gaggctgaaa ctttattaaa aacggagttg gaacaaacga ttttcccgaa
     9061 agagaaagca gaagtatgtc tggctttggc tgatttgcag attactttgg gaaaattgga
     9121 cgaagccgaa aagagtttaa gtcaggtccc cccttcccac ccgcatctgt atgctgccct
     9181 gtcccgcatc gcccaaagcc gtggagacag cctgcaagct gatttctacc acaaaagcta
     9241 cctccatcac ttatccgtcc tgcgacagga aaaagaacaa aatcaaatta cccaactcct
     9301 tcgtacctcg gaacagaaag aatgggaaaa acgtttaacc gatagccaaa aggcacaaaa
     9361 agaacaaata tatgtctggg tcacgctact tgtctcttgc agtaccggaa tctggggata
     9421 ttcccgctac cggcagaaaa gaaatgtcgt ttccctgtcc gaaacagatt tcttttcttc
     9481 agaaatctac ctgcgcttcc accgaaaaga agaatggaaa ccggttccca aagactggga
     9541 agaattgttg caagctttca accggaccta tccggatttc cgggaacggc tgaaaaggaa
     9601 aataccaaag ttgagcgaac aggaatggcg catgtgctgc ctgatcaaaa tggaagttcc
     9661 cccttctact gccgccatgc tcctttgctg cacgaaccag gcgatttcga tgcgccgcgt
     9721 acgcctgtac cagaaaatca caggtgaaaa gggcactcct gagctgtgtg attcctttat
     9781 tcgtgatttt taagcagatg tgaactgatg tgaaaccggg gaaatagccg tatcttctac
     9841 ttttgtctaa aaaaagcgta tgaaaaagat gttgttcggg cttatgacag ccattgccac
     9901 ttttaccgga tgcgaatcca aacaacccgc cggagaactc ccccggatcg atctgacagc
     9961 aacaagtttt gctttcgatc aagtagagat tgcagacgaa atcgaatcca tcgaatatgt
    10021 tccgttggaa ctaacggatg aatccctgat cgcagacgta ttggatctgt gtgtttcaga
    10081 cgaatatatc ttcgtctatt ctacccgtca ggacggtgtc ttgcagttcg accggaaagg
    10141 gaagtacttg cgctgcatcg ctaaaacagg aaacgggccg ggagaaaccg gacagatcat
    10201 ttcgctaacc gtagacgaag agaaccgcct cttctgtgtc agcgaatact tctccacctc
    10261 tttctactcc tttgatggag aatttatcaa aaagatagag aatccgcgcc cttactcgta
    10321 ccaattctct gttggcccga atacgatggc ggaattaggg aggatgtatg ttcccatgaa
    10381 cacgccgggc atgttcagtc tcggagtctt taattggggc acagacgata cgatcgcatt
    10441 tcggcatacg atcggggata tggatctgat gccgttggaa gaaacgagcc tgaaaggttg
    10501 gatattcagc ggcagtaagg acggcatact atgctattcg gaagggatag acacggtctg
    10561 ggatgtaaat gcaagaaata tcgctccggc ttttcttatc aacacgggat attctgtcga
    10621 ggaagaaaaa gaaatgcgct cttccaaaac cggtaatgag gcggtagacg ggaaatatag
    10681 cgtcttcagc ttctttgaga caccccggca ttacttcgtt aaatgtttcg aaggttccaa
    10741 ccaatccaaa ttctatttgt acggcttgga taaggctacc ggtgagttga aacgtgaaac
    10801 ttctccgctt aatgcccagg aattattcaa aaacaactgg acgctggcag gaataggctt
    10861 ccgaaatacg aaagacaacg gtcttcctat ctggccttac ctgtcttatc ccggcaaaaa
    10921 acaaatggta cagtttaata cagccgtgga aatcgaatat ctcaaagaga aatatcctga
    10981 tctcaagaag catctggtcc tgcaacagat aacggaagat tcaaatccgc tcatcacgat
    11041 ttatcatttg cgctgatctt ctcggatatt attcctacct ttgcgaacga accagtaaat
    11101 gtataagaac ttgaacgaga aagattttga aataatggcg cctgtcggtt cgtacgaatc
    11161 actgatggcg gctatccaag ggggagccga ttctatctat ttcggtatcg aaggattgaa
    11221 tatgcgttcg cgctcttcca ataactttac gacagacgat ttgcgcaaga tcgttgcgct
    11281 ttgtcgtgag cacggtatta agagctattt gaccgtcaat acggttattt atggggaaga
    11341 cctgcctctg atgcgcgaga ttatcgatgc ggcgaaggag gcggaagttt cagcgatcat
    11401 tgcggccgat gtggcagcta tgaactatgc caacagcatc ggacaggagg tgcatctttc
    11461 cacacagctc aacatttcca atgcggaagc actgaaattc tatgcccgtt ttgctgatgt
    11521 tgtcgtcttg gcgcgtgagc tgaatttgaa acaggtgcat gaaatctatc ggcagatcgt
    11581 cgaccagcag attacgggac cgaaaggaga actgatccgt atcgaaatgt ttgcccacgg
    11641 agctctctgt atggccgttt ccggtaaatg ttacctgagc ctgcacgaaa tgaacgcttc
    11701 cgccaaccgg ggagcttgca tgcagatttg tcggcgtgct tattcggtaa aagataaaga
    11761 cagcaatatc gaactggata tcgaaaacca gtatattatg tcgcctaaag accttaagac
    11821 aattcatttc atgaataaga tgatggatgc aggtgtacgg gtattcaaga tcgaaggacg
    11881 tgcccgcggt cccgaatatg tccgcctggt gaccgaatgc tataaggaag ctgtgcgtgc
    11941 ctattgcaat ggcacgttcg atgaaaagaa agttgccgct tgggacgaac gcctgcgcag
    12001 tgtgttcaac cgaggattct gggatggcta ttatttgggg caacggttgg gtgagtggag
    12061 tagcaaatat ggctccggcg cgactaagaa gaaagtgtat gttgccaaag gaatcaaata
    12121 tttcgacaag atcggcgtgg cggagttcga aatggaatcc ggtaacctga aagtgggtga
    12181 tgagatcctg attaccggac cgacaacggg tgcggttatg cagacgatag aagaaatccg
    12241 tgtggacttg aagccggtgg acgagaccgt taaaggtgaa cggttctctc tcaaggtgaa
    12301 cgagaagatt cggccgtctg accgattgta taaaatggaa aaggttcaac ttgaaaaggt
    12361 atttgaataa tgaaagagta tatttttaaa ctgacagaca aggtccgtga ctacgaatgc
    12421 gacctgcaag gagtggtcaa caactccaat tatcagcatt atatggaaca tactcggcat
    12481 gaattcttgg agtcgcttgg cgagaacttc ggaaagatgc acgaaaaagg ggttgacgga
    12541 tttgtatcgc gggtagaaat ccagtataag acctcgctca agagcggcga cagctatatc
    12601 tcttgcctca atgcctataa aaaaggagtc aagctcgtat tcgagcagga tatatatagg
    12661 gcttctgaca atgcattggc gacgaaagga atcgtcgagt cggttatcgt tgagaacgga
    12721 aagttgacac gcggtgaata tttcgacgaa atgctaaaaa gaatagaaca tacatgactg
    12781 acaaacggat ttaccaaatc ggccttacta tgataaacgg cgtgggagat atcctggcgc
    12841 gtcatctcct gcaggctttg ggagaagcag aggctgtgtt tactgaaaag caacagttgt
    12901 taggaaggat ccctggtatc ggcagcaata ttgctgccga aatcaaacgc ccggaaatct
    12961 tgcaacgggc ggaaaaagag ttggctttta tcgagaaaaa caatatttcc tgttattatc
    13021 tgactgatac agattatccg gtgcgcttga gagaatgtcc ggatgcccct atacttttct
    13081 attttaaggg aaatactaac cttgatgcga cccgtatcat cagtattgtg ggtactcgca
    13141 acgcgaccga atatggtcgg gagcttaccg aatcccttat aaaagacttg gcaaaagtga
    13201 tcccggactt gttggtcgtg agtggattgg cttacggcat cgatatctgt gctcaccgga
    13261 acgctttgta caaccgactt ccgactgttg ctgtgctggc gcatggcttg gatcgtatct
    13321 atccttcctg ccatcggaat acggctgtcg aaatgctgga atcgggcggt ctgttgaccg
    13381 attttcccag cggtacagaa ccagaccgtc caaatttcct ccggaggaac cggattgtcg
    13441 ccggaatctc ggattgtacg atcgtggttg aatcggcaga aaaaggaggc tctttggtaa
    13501 ctgccgatat tgcattctct tatggccggg atgtctatag ctttccaggg cgtgtcggtg
    13561 acagccattc caaaggatgc aacaatttga tccgacaaaa taaagccggc ctgatcactt
    13621 ctgcggacga tctgctctcc gctctttgtt gggatatcca agctggggct actcccgttc
    13681 aaacggagtt gtttttcgcc gaagcggaaa cattcacctc ggaacaaaat ccggttttag
    13741 ccattatgcg aacgcggaat gagatccata tcaacgagct tgcctcagtg ttggagatac
    13801 cggtacatca actctctatg ctattgttcg aactggaaat aaacgggaag gtaaaagcgt
    13861 tgccgggaaa tctctataag ctgtcctgac cggctttttc gtatacgatt tgtatgtggg
    13921 agaagaaacg gaacctctat aaacaattaa aggctgtctc acgacaaccc ctaaccaact
    13981 ttgttaacct taaatctaat actattatga aaaaaccaca ttgcaaagat acactcgtca
    14041 agagcgtttg tcaagcattt tgtcgctaat acttgttaat cagatgagca taaatagcaa
    14101 aaagatttta atcggctata aagagtcctt taaactgcgt tattttgtta aatcgagtcc
    14161 ttgaaacagg tacggatagt ccgtttcgat cacgtcggga cgagtgctga tctctgaccg
    14221 gtaaccggcg gttttctctg tttccgtttt cgcgcgatca tgtgtcggag caacggaaat
    14281 catgcacatg actccgttac ggtgcagagc gtcatacagt ggttgctgtt caggcttcat
    14341 cttcgggcct acataagcca ttacctgttt ccaggggatg ccggcttttt cataattatc
    14401 gaattcttcc cgattcttac accagcaaga aaacatcgca tccggtttcc ggtcgagata
    14461 atagcgggct tgactggcgt tatgtaccgt gtacatgacg ttaacaggct tttctgtttc
    14521 tataaaatca gccataactt ctaaaggtac atccttgata tccaaattca ggattgtttt
    14581 gcctttgctc cattccaggc attcttttaa agttggaatt ttgaaggctg tcacgttgcc
    14641 gtttcggtcc accagattga attgttgcag ttctgcataa gtgtaatctg aaacctttcc
    14701 tttcccggta gttgtccggt cgatggtttc gtcgtgcatc aatacgatta tcccgtcttt
    14761 tgtcaaacgc ggatctatct cgaaaaacga ttc
//
