LOCUS       c00013_gnlPro..        14458 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MBCHICJG_13.
ACCESSION   c00013_gnlPro..
VERSION     c00013_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:20:16
            Original ID  :: gnl|Prokka|MBCHICJG_13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14458
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14458
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[219:4458](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(220..4458)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..14458
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14458
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             3..281
                     /locus_tag="ctg13_1"
                     /transl_table=11
                     /translation="IFCLHSVGVARYAALIQAKSSTSQAQPSENERILICGLGASVGYE
                     RVERVFNTPRLKSQIRILSFSEGVCLASILPAANQISTSSPLLPASI"
     CDS             complement(220..4458)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_2"
                     /sec_met_domain="HGD-D (E-value: 6.8e-64, bitscore: 207.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 4.5e-37, bitscore:
                     118.6, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHALGIDIGSTTVKVTVINESHDILFSDYKRHFANIKGTLQTLL
                     SEAREKLGNLTIHPTVTGSGGMAISEYLHIPFCQEVVCVANALQDYEPKTDVAIELGGE
                     DAKIIYFNNGIEQRMNGVCAGGTGSFIDQMASLLQTDATGLNEYARDYDTLYPIAARCG
                     VFAKSDIQPLINEGATKENLAASIFQAVVNQTISGLACGKPIKGYVAFLGGPLHFMPEL
                     KNAFIRTLNLDEEHIIDPPYSHLFAAKGAALNAKEECSFTLDDLLKEFESDIQLAVEVE
                     RMEPLFKDEKEYDEFIEEHNQFKVKKADLATYSGKCYLGIDAGSTTTKLALVGEDGSLL
                     YRFYDNNNGSPLNTTIRAMKELKELLPPAAKISGSCSTGYGEALIKAALQLDHGEVETM
                     AHYYAAAFFEPDVDCILDIGGQDMKCIKIRNHAVDNVLLNEACSSGCGSFIETFAKSLN
                     YSVADFAKVALFAPSPIDLGSRCTVFMNSKVKQAQKEGASVGDISAGLAYSVIRNALLK
                     VIKLTDPKQLGKKIVVQGGTFYNDAVLRSFERISGCHAVRPDIAGIMGAFGAALIARER
                     EEETGDTQMLSIDEIINLEYSTSMSRCQGCNNHCILTINKFNNDRQFISGNRCERGLGL
                     EKNHEHVPNLYEYKYKRIFGYKALKPDEAKRGVIGIPRVLNMYENYPFWYTFFTNLSFR
                     VLLSPKSSRKIYELGIESIPSESECYPAKIAHGHVMWLLKKGINTIFYPCVPYEEDQME
                     GANNHYNCPIVTSYAENIKNNMEELRDPNVLFMNPFLALDNADALKVRLYDELSKHFDV
                     TKEEIDHAVDEAYKEAAQVRKDVQAKGEETLAYLAETGKMGIVLCGRPYHIDPEINHGI
                     PELINSFGIAVLSEDSICHLGHVERPLIVSDQWMYHSRLYAAANYAKKNKQLEVIQLNS
                     FGCGLDAVTTDQVNDIMTNSGRIYTVLKIDEVNNLGAARIRIRSLIAAVKIRNRKHIEP
                     HPVPANIEKVEFTKEMKKDYTILIPQMSPIHFDLLTPAFRHCGYNVEILPEMGKQAVDT
                     GLKYVNNDACYPSLIVVGQIMTALTSGKYDLNKTAVIISQTGGGCRATNYIGFIRRALA
                     KNGYGQIPVISLSVQGIEKNEGFKFTPALLVRALQGVIYGDLFMRVLYRVRPYEKVKGS
                     ANHLHEVWKKRCIKSLEKARYGEFKKNIRGIIRDFDRLPITDEKKPRVGIVGEILVKFL
                     PDANNHLVELLEEEGAEAVMPDLLDFMFYSFYNSNFKAEYLGKSTKAAKLCNMAISALE
                     AYRGFLRKELERSDRFTAPPHIEELAEYAKPIVSLGNQTGEGWFLTGEMVELIKQGAPN
                     IVCTQPFACLPNHVVGKGVIKELRRKYPESNIVAIDYDPGASEVNQVNRIKLMLATAEK
                     KLKSDLPQAR"
     CDS             4884..5255
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_3"
                     /sec_met_domain="LysM (E-value: 2.3e-14, bitscore: 44.0,
                     seeds: 155, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKVYVNICDTKKCPGPVYAVKTGDTLYSIAQRHHCRVRTLLDL
                     NPFVDIYNLQPGEEICVPDCRGQGKVDFRPYVVKEGDTLKIILKNVSMTFEELAKVNRI
                     LYNLTVPAGTILLVPAKKE"
     CDS             5451..6389
                     /locus_tag="ctg13_4"
                     /transl_table=11
                     /translation="MIRIFKTTDSGIRKVAVAEEGCWIALTNPTAEELSTTADQFNIDV
                     DDLKSPLDEEERSRIQVEENYTLIILDIPTIEERKGREYFYTIPFGIIFTDKYIFTVCL
                     VDSPVLTVFMDGRVRDFYTYKRTRFIYQMLYRNATMFLQYLKIIDKKSDEVEKKLHISQ
                     RNQELIEMLDLEKSLVYFTTSLRGNEVVLEKLMRNTSIPRYEDDEELLEDVIIENKQAI
                     EMAKIYSDILSGTMDAFASVISNNLNIAMKFLSVITIVLTVPTIVTSALGMNVAGIPFA
                     NNPYGFWIVVGISLLLTLIAGAIIAKNKHFK"
     CDS             6536..7351
                     /locus_tag="ctg13_5"
                     /transl_table=11
                     /translation="MNWLDKLERKFGRYAIRNLPLYIVMLYAIGAVLNILTKGSYYYYV
                     ALNPYMILHGQIWRLLGFLIVPPNASLIFIIFVLMFYYSIGESLVQVWGAFRFNMYILI
                     GVLATIVASFIVYFIYPSTMIFMDTFYLNLSMFLAYATIFPEMRVYLYGILPLKVKWMA
                     WFDVALLVWQFVVGGLGARIAIVVSLLNFLLFYFSSRNYKKVSPKEIHRKRAYRKASSV
                     ASNKPYRHKCAVCGKTELDDPNLEFRYCSKCNGNYEYCNEHLFTHTHVK"
     CDS             7793..8722
                     /locus_tag="ctg13_6"
                     /transl_table=11
                     /translation="VLYVLLLLLKILGILLLLFIGLVLLVLLTPIQYSFELEKEEQREP
                     KFMVRVTWLFWLFYFKTSYIEKVFDYRIRILGYQIAGNQPEFLEKQKERQKKKSQKEKA
                     KEERKTAETPAEGKSRSIDSVSKQKAEKAVPKEKSSDVSEGREKTKEKDSGDDKNSKDK
                     KKNKEKKQKDGKKPKKESSLKKIKSKIKSLKETKVNLDKMPWREWLELGKDVLIRFLKH
                     ALPGKLEGNIAFGTGNPEYTGYITGIAAVFYPKYGEHFSLYPDFERKMFEAKCRGRGRI
                     RLGYMLVLAVSILKEKSVRTMIKNIILG"
     CDS             8738..9178
                     /locus_tag="ctg13_7"
                     /transl_table=11
                     /translation="MDKQNFDTTVNSLFSGMDHVLSSKTVVGEPQVIGDTIILPLVDIS
                     FGMGAGAFNKEKGSSAGGGIGGKMSPSAILVIHNGQTKLVNIRDQDAVTKVLDMVPDAV
                     NKVVSIIKGEDAEDKVDPEVESAVNKAAQAEASVVDVDGAGI"
     CDS             10019..10375
                     /locus_tag="ctg13_8"
                     /transl_table=11
                     /translation="MKGQMHTDLGQVIIDEEVIATYAGINAIECFGIVGMASVNMKDGF
                     AQLLKRDNVSKGVHIKINDNKIYIDFHIIVVYGVSIATVTENLIQNVKYRVEKFTGMSV
                     EKINIYVEGVRIVD"
     CDS             10544..12253
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dak2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_9"
                     /sec_met_domain="Dak2 (E-value: 2.5e-40, bitscore: 128.9,
                     seeds: 138, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNSHTIDAKTFQKLFLAGANRINSRKDYINELNVFPVPDGDTGTN
                     MSLTILAAAKEVGAVAEPTMATICKAISNGSLRGARGNSGVILSQLFRGFTKAVSKADS
                     LGKDEITAGFTRAVETAYKAVMKPKEGTILTVAKGMADKAEELVDEDMDVIAFCEAIVA
                     YGYEVLSKTPDMLPVLKEAGVVDSGGQGLMEVLQGIVDALTGKVTDIEVPAEAASMSSA
                     VISAPKADISTADIKFGYCTEFIILLDKPLTKEDEKGLKKFFLSIGDSLVLVADEEICK
                     VHVHTNHPGEAFEKALTFGALSNMKIDNMRLEHQEKLIKDAENEAARQRQQEAEEEELA
                     AKEAAAEKPAKEVGFIAVSVGEGLTDIFEGLGVDYLIEGGQTMNPSTEDMLNAIEQVNA
                     KNIFILPNNKNIILAAEQARDLTEDKKIIVLPTKTIPQGISAMIGYMPEAGVDENEENM
                     KEAYQDIASGQVTYAVRDTVIDGKEIHNGDIMGINDDGIAAVGKNLTETTLELLSTMAD
                     EDSELICLYYGADVTKDDADTLSDAIEDKFPECEVEVNFGGQPIYYYMISVE"
     CDS             12419..14440
                     /locus_tag="ctg13_10"
                     /transl_table=11
                     /translation="LGIPVREIKGIGEKTEKLLAKLDIETVDQLVHHYPRCYTTYPEPI
                     SISEIKTGQRCSIEAEIASPIHLKTVRKLKLCTGLIADVSGQLFVRWFNMPYLRNTLKQ
                     GERWIFTGTPIYKDGRLMLEQPEYCKREKYLQLMETFQPIYPLTTGLSNKTVQKAQAAA
                     FEMYREEEYLPETVRNYYDLEPVNTALREVHFPTGTEHLMEAKKRIIFDEFFRFFSALE
                     LVKDREEQALNHYIIPMEEPVKRFVENLPYPLTGAQKKVLNEIRQDFSDTMAMNRLLQG
                     DVGSGKTIVAMTAMYAAVLAGYQAALMAPTEVLAEQHYQNFVKLLSPLGITVALLTGST
                     KAKEKREIKAACASGEIQILIGTHTVIQDDVAFDNLAFIVTDEQHRFGVKQRDAFMKKG
                     KDPHVLVMSATPIPRTLGIILYRDLDVSIMNEMPASRLPIKNSVVGTSYRPAAWEFIRK
                     QVALGHQAYVICPMIEENEKMDLENVEEYARMLSQALPPSITVEALNGHMRPAEKNDIM
                     ERFSKNEIQILVSTTVVEVGIDVPNATVMLIENAERFGLAQLHQLRGRVGRGKAQSYCV
                     FISGSEKEEAMERLSIIGHSNDGFEIANEDLKLRGPGEFFGVKQSGTMNFALGDIYSNA
                     DILKMASEAVDYLKKEGYNFQKLHQYSLEKNLNFAKNI"
ORIGIN
        1 gtatattttg ccttcattca gttggcgtag cccgctacgc cgccctcatt caggcaaaat
       61 cttccacatc ccaagcacag ccctctgaga atgaaagaat ccttatttgt ggcctcggag
      121 caagtgttgg atacgagcga gtagagcgag tattcaacac gccgcgacta aagtcacaaa
      181 taaggattct ttcattctca gagggcgttt gtttggcgtc tatcttgcct gcggcaaatc
      241 agatttcaac ttcttctccg ctgttgccag catcaattta attcggttta cctggtttac
      301 ttcgcttgct cctggatcgt agtcaattgc gacgatatta gattccggat acttacggcg
      361 cagttccttg ataacaccct tacctacaac gtggtttggc aggcaggcaa atggctgtgt
      421 gcaaacaata tttggggcgc cctgtttgat aagttcaacc atttcaccag ttaagaacca
      481 tccctcaccg gtctggttac cgagggatac gattggtttt gcgtactcgg caagttcctc
      541 aatgtgaggt ggtgcagtga aacgatcgct tctttctaat tcttttcgca ggaagcctcg
      601 gtaagcttcc agtgcagaga ttgccatatt acataactta gcagcttttg tagattttcc
      661 gagatattct gctttaaaat tactattgta gaaggagtag aacataaagt ctaataaatc
      721 tggcattact gcctctgccc cctcttcttc taaaagttct accagatggt tgtttgcgtc
      781 tggaaggaat tttacgagga tttctccaac gataccaaca cgaggtttct tctcatctgt
      841 gattggtaat ctgtcaaagt cgcggataat gccgcggata tttttcttaa attctccata
      901 tcgtgctttc tcaagagatt taatacaacg ctttttccat acttcatgta aatgatttgc
      961 agaacctttt actttttcgt atgggcggac gcggtagaga acacgcataa ataaatctcc
     1021 gtaaataact ccctgaagag cacgaactaa aagtgccgga gtgaatttaa aaccttcatt
     1081 cttctcaatt ccctgtacgc ttaaactgat aactggaatc tgaccgtaac cgttcttagc
     1141 taatgcacgg cggatgaatc cgatatagtt tgtcgcacga cagccaccac cagtctggga
     1201 gatgataacg gctgttttgt tcagatcgta tttgccggaa gttaaggcag tcataatctg
     1261 tccaacaacg ataagagatg gatagcaggc atcgttattt acatatttta atccagtatc
     1321 tactgcctgt ttccccattt ccggcaaaat ctctacgtta tagccacagt gacggaaggc
     1381 aggggtgagc aggtcgaaat gaattgggga catctgagga atcagaatgg tgtagtcctt
     1441 tttcatttct tttgtaaatt ctactttttc gatatttgcc ggaaccggat gtggctcaat
     1501 gtgcttacgg tttctgatct ttacggcagc aatcagagaa cggatacgga ttctggcagc
     1561 acctaagtta tttacctcat caatcttaag gacggtataa atacgtccgg aattcgtcat
     1621 aatatcattt acctggtcgg tagttaccgc atcaagacca cagccaaagg agttaagctg
     1681 aatgacttct aactgcttgt tcttctttgc gtagtttgcg gcagcgtaca gacgggaatg
     1741 atacatccac tggtcagaaa cgattaatgg acgttcaaca tgacctaagt gacagatgga
     1801 atcttcactt aatacggcga tgccaaaaga gttaatcagt tcaggaatac cgtggttaat
     1861 ctctgggtcg atatggtaag ggcgaccaca aagaacaata cccatctttc cagtttctgc
     1921 gagataagca agtgtttctt cgccctttgc ctgtacatct tttcttacct gtgcagcttc
     1981 tttataagct tcatctacgg catggtcaat ctcttctttt gtcacatcga aatgtttaga
     2041 taactcgtca taaagacgta ccttcaaggc atctgcatta tcgagtgcta agaatgggtt
     2101 cataaaaagg acattcggat cacggagctc ttccatgttg tttttaatat tttctgcata
     2161 agatgttacg atcgggcagt tgtaatggtt gttggcacct tccatctggt cttcctcata
     2221 aggaacacaa ggatagaaaa tggtgttgat acccttcttt aaaagccaca ttacatgtcc
     2281 gtgtgcaatc tttgcaggat aacattcgga ttcacttgga atggactcaa taccaagttc
     2341 gtaaatcttt cgggaagact ttggagaaag caatacccgg aaagaaaggt ttgtaaagaa
     2401 tgtataccag aatggatagt tctcatacat attcagtact cgtggaatac cgataacacc
     2461 acgttttgcc tcgtctggtt ttaatgcttt atatccaaaa attcgtttat atttatattc
     2521 gtaaaggttt ggtacatgct catgattctt ttcaaggcca agaccacgtt cacaacggtt
     2581 accagaaata aactgacggt cattgttaaa cttattaatg gtaaggatac agtggttgtt
     2641 acatccctga cagcggctca tggaagtgct gtattccaag ttgataatct catcgatgga
     2701 gagcatctgt gtatctccag tttcttcctc acgctctctt gcaattaagg ctgcaccgaa
     2761 agcacccatg ataccggcaa tatctggacg aacggcgtga cagccggaaa tacgttcaaa
     2821 gcttcgaagt accgcatcat tatagaatgt accaccctga acaacgattt ttttaccaag
     2881 ctgtttgggg tcggttaact taataacttt taataaggca ttacggataa cggaataagc
     2941 aaggccagca gaaatatcac caacgctggc gccttctttt tgtgcctgtt ttaccttgga
     3001 gttcataaat acagtgcagc gggaacctaa gtcgattgga gatggggcaa acagcgcaac
     3061 ctttgcaaaa tcagctacag aatagttcag agattttgcg aaagtttcga tgaaagaacc
     3121 acatccagaa gaacaggcct catttaaaag tacgttatct acagcgtggt tacgaatctt
     3181 gatacatttc atatcttgtc cgccgatatc taaaatacag tctacatctg gctcgaagaa
     3241 agcggcagca tagtaatgtg ccattgtctc tacttcgccg tggtcaagct gcagtgcagc
     3301 cttaattaat gcttcaccgt aaccagtaga acaggaaccg gaaatcttcg cagcaggagg
     3361 aagtaactcc tttaactctt tcatagcacg aattgttgta tttaacggac ttccgttatt
     3421 attatcgtag aaacggtata agagggaacc atcttctcca actaaagcaa gctttgttgt
     3481 cgtagatccg gcatcaatac cgagatagca tttgccactg taggtagcta agtctgcctt
     3541 tttcaccttg aattggttgt gctcttcgat aaattcatca tattcttttt cgtctttaaa
     3601 aagaggctcc atacgttcta cttctacagc aagctgaatg tcggattcaa actcttttaa
     3661 gagatcatct aatgtgaagg aacattcttc ttttgcgttt aatgcggcac cttttgctgc
     3721 aaaaagatga gagtatggag ggtcgataat atgttcttcg tccagattta aagtacggat
     3781 aaatgcattc tttaattctg gcataaagtg aagaggacca ccaaggaaag cgacatatcc
     3841 cttgattggt ttaccacagg caagaccact gattgtctgg tttactacag cctggaagat
     3901 agaagcagca agattttctt ttgttgcccc ctcattgatt aatggctgaa tatcagactt
     3961 tgcgaaaaca ccgcaacgag cggcgattgg atagagggta tcgtaatcac gggcatattc
     4021 attaagaccg gttgcatctg tctgtaaaag acttgccatc tggtcgatga aagaaccagt
     4081 accaccggca catacaccgt tcatacgctg ctcaattccg ttattaaaat aaataatctt
     4141 ggcgtcttca ccgccaagtt cgattgctac gtctgttttt ggttcataat cctgtaaggc
     4201 attcgccaca caaactactt cctgacagaa tggaatatgt aagtattctg agattgccat
     4261 cccaccggaa ccagttacgg ttggatggat tgtgagattg cctagctttt ctctcgcctc
     4321 agataataag gtctgtaaag ttcctttaat atttgcaaaa tgtcgtttgt aatcggaaaa
     4381 aaggatatca tggctctcat tgataactgt taccttaacg gtagtagaac caatatcaat
     4441 acctaatgcg tgtttcatga ttaattaatc atctccttta gtaaaatgtg tattcatgtt
     4501 gtgtattaaa ataaggtaat ctaatgttca gaatacattt ataacaccgt ccgcgataca
     4561 cttcgcttgc cgatgccacc gtatcgtctt gttcagtcac tttgttgatg aaaaagcatt
     4621 ctgcgttatt tgacagaaag gcaatgagac agacactatg gctctgaatc actatatata
     4681 gataaatttc tcaatatcca aaccattata aacgagttga acgtaaaata caacaaattt
     4741 cgaaaaaaag atataatgaa tggaaaatgt ttacaaaaaa caaaaggaga ggggagtatt
     4801 tgtatgagga gtttttcacg ataaagtacc tttttctctg actgtcatat tttataattg
     4861 aggaagaaaa aggaagagca tctatgagtg aaaaagttta tgtaaacata tgtgacacca
     4921 aaaaatgccc cggcccggtg tatgcagtaa agacaggaga tacgctgtat agcattgcac
     4981 aaaggcatca ttgccgggta agaacacttc ttgatctaaa cccttttgta gatatatata
     5041 atttgcagcc gggtgaggaa atctgtgtac cagactgcag gggacagggg aaagtagatt
     5101 tccggcctta tgtagtaaaa gaaggggata cattaaaaat tatcctgaaa aatgtttcaa
     5161 tgacctttga agaattagca aaggtaaacc gtattttgta taatcttact gtaccagcgg
     5221 gaacgattct gctcgttcct gcaaaaaaag aataaatgaa aaagaaaagc agttaaaaaa
     5281 tagtaaaaaa atcacagaaa tgcgtttgac aaagtattag atatttctta taataaattt
     5341 aaacggtttc agttatgtaa gagtccgcga aacggactct ttctttcgtt ttgccaagat
     5401 agagaagatg cagactgaga tacgataaac tgttgaaaga gggaagtctc atgataagaa
     5461 tttttaaaac gaccgattca gggattcgca aagttgcagt ggcagaggaa ggatgctgga
     5521 tagcccttac caatcctacg gcagaagaac taagtaccac agcagaccag tttaacattg
     5581 atgttgacga tttaaaaagc cccttggatg aggaggaacg ttcccgtata caggtggagg
     5641 aaaattacac attaattatc ctggatattc caacaatcga agagcgtaag ggaagagaat
     5701 acttctatac gataccgttt ggaattatct ttactgataa gtatatattt accgtctgtc
     5761 ttgtagactc accggtactg accgtattta tggatggaag agtgagggat ttttatacgt
     5821 ataagagaac tcgtttcatc taccagatgt tataccgcaa tgcgacgatg tttctgcagt
     5881 atctgaagat tattgacaag aagagtgatg aagtggagaa gaagcttcac atttctcaga
     5941 gaaatcagga attgattgaa atgcttgatt tagagaagag tcttgtatat tttacaactt
     6001 ctctgcgagg caacgaggtt gttcttgaga aactgatgcg taatacatcc attccacgtt
     6061 atgaagatga cgaggagtta cttgaagatg ttatcatcga gaataagcag gcgattgaga
     6121 tggcgaagat ttatagtgat attttaagtg gaacaatgga tgcctttgct tctgttatat
     6181 cgaataactt aaatattgcg atgaagtttt tgtcagttat taccattgtg cttactgtac
     6241 caacgattgt tacaagtgcg cttggtatga acgtagcagg aattccattt gcgaataatc
     6301 catatggatt ttggattgtt gtaggaatct ctttattact gactctgatt gccggagcaa
     6361 tcattgccaa gaataaacat tttaaataat tgaatatgta tgagacagcc gggatttccg
     6421 gctgttcatt tataaacaaa aatattttat taagaatgta cgcttgggat ttttactgca
     6481 cttgtttttg cagaaggttt cttgtcagta cattgaaagt taaaggagga gtgccatgaa
     6541 ttggctagat aagctggaac gtaaatttgg aagatatgcg atacgaaatc tgccgctgta
     6601 tatcgttatg ctgtatgcga taggagcggt acttaatatt ttgacaaagg gttcttatta
     6661 ctattatgtc gcattaaacc cgtatatgat acttcatgga cagatttgga gactgcttgg
     6721 tttccttatt gtgccaccga atgcaagtct catttttatt atttttgtac tgatgtttta
     6781 ctattcgatt ggagaatctt tagtacaggt atggggagca tttcgcttta atatgtatat
     6841 ccttatagga gttcttgcga caattgtggc atcatttatt gtatatttta tttatccatc
     6901 aacaatgatt ttcatggata ctttttattt gaacttatcc atgtttttag cctacgccac
     6961 gatattcccg gagatgcggg tatatcttta tggtattctt ccgctgaaag taaagtggat
     7021 ggcgtggttt gatgtggcgc ttttagtttg gcagtttgtc gttggaggac ttggagcaag
     7081 aattgctatt gtagtaagtt tactgaactt tctgctgttt tacttctcat caaggaatta
     7141 taaaaaggtt tctccaaaag agattcacag aaagagagca taccggaagg catcatctgt
     7201 ggcttcaaat aaaccatatc gtcataagtg tgcagtctgt ggtaagacag aattagatga
     7261 cccaaattta gaattccgtt actgctcaaa gtgtaatgga aattatgaat attgcaatga
     7321 acatttattt acacatacgc atgtaaaata aagcaatatt aaaagagtta tattctttca
     7381 aataaatctg aaaaattaat ggatagaata aagatataat ataagttgca aataaatcat
     7441 gacaggaggc ggtcttttgt tgacaatatc agaacatata atgattgggg agacgatttc
     7501 ccacgatgcg aaggctatat tgcggggagt ccgccatcct tttatatgga agaaaggact
     7561 ttggtatggt attacgactt cctgtgggaa agatgtgatc atgtatattc tttcttcacg
     7621 agagatgaga cagaagtttt atcagaacaa tgatttaaag ctgttgggac ttgcaggttc
     7681 tatgaaagag gcttatgaaa tcgtgttaaa acttgtgcag atgggatata atagtgattg
     7741 tatctatgag atgaatgatt atctggagaa gttttaaaac aggaggagaa atgtgctgta
     7801 tgtattatta ttactattaa aaatacttgg aatactgctc ctgttattta tcggacttgt
     7861 tttgcttgtt ctgctaactc cgattcagta ttcttttgaa ctcgaaaagg aggaacagag
     7921 ggaaccaaag tttatggtaa gagttacctg gctgttctgg cttttttatt ttaagaccag
     7981 ttacatagag aaggtctttg attaccggat acgtatactg gggtatcaga ttgccgggaa
     8041 tcagccggaa tttcttgaaa aacagaaaga acggcaaaaa aagaagtctc aaaaggaaaa
     8101 agcaaaagaa gaacgtaaaa cagcagagac accggcagag ggaaaaagtc gaagcataga
     8161 ttctgtttct aaacagaaag cggaaaaggc agtccctaaa gagaaatcct cagatgtgtc
     8221 agaaggcaga gaaaaaacaa aagagaaaga ctctggagat gataaaaata gtaaagataa
     8281 gaaaaagaat aaagaaaaaa agcaaaaaga tggaaagaaa ccaaagaaag agtcttcttt
     8341 aaagaaaata aaaagcaaaa taaaaagctt aaaagaaaca aaggttaatt tagataaaat
     8401 gccgtggcgg gaatggttag agctgggaaa ggacgttctt attcgctttc taaagcatgc
     8461 tcttccggga aagctagaag gaaacattgc atttggaact ggtaatccgg aatatacagg
     8521 atatattaca ggaattgcgg ctgtttttta tccgaagtat ggagaacatt tttctttata
     8581 tccggatttt gaaagaaaga tgttcgaggc caagtgcagg ggaagaggaa gaatccggct
     8641 gggatatatg cttgttctgg ctgtttctat attaaaagag aaaagtgtaa gaacaatgat
     8701 taaaaacatc attttaggtt aaacaggagg gcgtacaatg gataaacaaa actttgatac
     8761 aacagtgaat tctttattta gtggaatgga ccacgtatta tcttcaaaga cagttgttgg
     8821 agaaccacag gttattggag atacgattat tctgccactt gttgacattt cctttggaat
     8881 gggagcaggg gcctttaata aagaaaaggg aagcagtgca ggcggtggaa tcggaggtaa
     8941 aatgtcccca agtgctattt tagttattca taacggacag acaaagcttg tcaatatcag
     9001 agatcaggat gccgttacca aagtacttga tatggttcca gatgccgtaa ataaagttgt
     9061 ttctattatt aagggagagg acgcagagga caaagttgac ccggaagtag aatctgcggt
     9121 gaataaagca gcacaggcag aggcttctgt tgtagatgta gatggcgcag gaatttaaaa
     9181 ggtattcggt attcagttaa cgtgagatta ccacgttatt ttcgtgcagg aaaaatcttc
     9241 cacgaagtgt aatgcatatc gtatagaaag cggtttttaa acacactttg ggttgcctta
     9301 gatcaatcaa ataaaaaaag tgaagatttt taaaagtttt ccttgcaatt tgttttgatt
     9361 tctgatagta tagactcgtt gtaagtctgt cagacttaag tatattcgcg aggaggtgct
     9421 atcatggcaa gatgcgctat ttgtgacaaa ggtgctcatt tcggtatcaa agtgagtcat
     9481 tcacatagaa gatcaaacaa aatgtggaaa tccaacatta agtctgtaag agtgaaagtg
     9541 aacggagctt ctaagaaaat gtatgtttgt acttcttgtt taagatcagg taaagtagaa
     9601 cgtgcgtagt tttactgtca ctgaggataa gagaagactc taatctttgt ccttacagga
     9661 atgtatgcag atatgagtta agagggaatc agtgattccc tcttttttct tttctgttaa
     9721 aatcggtcac aaaacagcag atatccaagc aggatgctga tgaccagaat aatgaacttt
     9781 actgcaaagc cggtgagaaa gcagctcagg aacagaccaa aggaaaagca aaaaagagcg
     9841 aatccgcata attttttcat aaaatctccc caatatgttc cttataatag tatatgggaa
     9901 gatacttctt ttgtttcagg agaaagcact taaatggaag aattttatgt ttgtggttcc
     9961 aatttcaccg aaaagaggtt atactataga aaacgataat aaaacggagg gatagtatat
    10021 gaagggacaa atgcacaccg atttaggtca ggttattata gatgaagagg ttattgcaac
    10081 ttatgccgga attaacgcga ttgagtgttt tggtatcgtt ggaatggcat ctgtgaatat
    10141 gaaagatggt tttgcccagc ttttaaagag agacaatgta agcaagggcg ttcatatcaa
    10201 gataaatgat aacaagattt atatagattt tcatattatt gtagtatatg gtgtctccat
    10261 agctacagtt acagagaatt taattcagaa tgtaaagtac cgcgtggaga agtttaccgg
    10321 tatgagtgta gagaaaatta atatttatgt agagggagtc cgtatcgtag attagaacgt
    10381 gtttgaaaaa tgctttctgc aaattggggc gtgcaggttg ctggaatgat ttttcaaaca
    10441 cgctctaaga taacgcttta gaagggattc ctttttatag aataaaagaa caagataact
    10501 actatgaatt atagataaaa caggtaaata aggaggaaat gttgtgaaca gtcacaccat
    10561 agacgcaaaa acttttcaga aattgttttt agccggtgca aaccgtatta attccagaaa
    10621 agattatatc aacgaactga atgtatttcc ggttcccgat ggagataccg gaacaaatat
    10681 gtccctgaca attttagcag cagctaagga agttggagca gttgctgaac ctacaatggc
    10741 tacaatatgt aaagctatca gcaatggttc tcttcgtgga gcccgtggta actctggtgt
    10801 aatcctttcc cagttattcc gaggattcac aaaggcagtt tctaaagcgg attctcttgg
    10861 taaggatgag attacagccg gatttacaag agcagtagag acagcgtata aggcagttat
    10921 gaagccaaaa gaaggaacca tccttacggt tgcaaaagga atggcagata aggcagaaga
    10981 gttagtcgat gaggatatgg atgttatcgc attctgcgag gcaatcgttg cctacggcta
    11041 tgaagtcctt tctaagacac cagatatgct tccggtatta aaagaggcag gtgtagtaga
    11101 ttctggcgga cagggtctta tggaagtgtt acagggaatc gttgatgctc ttaccggcaa
    11161 ggtaacagac attgaagttc cggcagaggc agcgtctatg tcatctgcag taatcagtgc
    11221 accaaaagca gatatttcta cagcagatat caagtttggc tactgtacag aatttattat
    11281 tttgttagat aagccgctca caaaagaaga tgagaaggga ttaaagaagt tcttcctttc
    11341 tataggtgat tctttagtat tagttgcgga tgaagagatt tgtaaagtac atgtacacac
    11401 aaatcatcca ggagaagcct ttgaaaaggc cttaacattt ggtgcgcttt ctaatatgaa
    11461 gattgacaat atgcgcttag agcatcagga gaagctcatc aaagatgcag agaatgaggc
    11521 agcccgtcag agacagcagg aagcagaaga agaggaactt gccgctaaag aagcagctgc
    11581 agaaaaacca gccaaagaag ttggatttat tgcagtatct gttggtgagg gacttaccga
    11641 tattttcgaa ggtcttggtg tagattacct tattgaaggc ggccagacga tgaatcctag
    11701 cacagaggat atgcttaacg caatcgagca ggtcaatgca aagaatatct ttatcctgcc
    11761 aaataataag aatattattc ttgcggcaga gcaggccaga gatttaacag aagataagaa
    11821 gattatcgtt cttccaacaa agacaattcc acagggaata tccgcaatga ttggatatat
    11881 gccagaagca ggtgtggatg agaacgaaga gaatatgaaa gaggcttatc aggatattgc
    11941 aagcggtcag gttacttacg cggtacgaga cacagtaatt gatggaaagg aaattcataa
    12001 tggagacatc atgggaatca atgatgatgg aatcgctgca gtaggaaaga atcttactga
    12061 gacaacatta gaattacttt ctacaatggc agatgaagat tcggaactta tttgccttta
    12121 ctatggagcc gatgtaacca aagatgatgc agatacactt tccgatgcaa ttgaggataa
    12181 gttcccagaa tgcgaagtag aggtcaactt tggcggacag ccaatctatt actatatgat
    12241 ttctgtcgag taagataaat gaaataatga tataatgaaa aaagagggaa taaatcactc
    12301 ttttgtggca gcaattccgt gtattgacat ggaatcgctg ctattttcat ataagagtgt
    12361 tttgattaag ataaaataat attaccacat gatgcatgtg gaggaaggag aatctcagtt
    12421 gggaatacca gtaagggaaa ttaaaggaat tggagaaaag acggaaaagt tacttgcaaa
    12481 gcttgacata gagaccgtgg atcagttggt gcatcactat cctcgttgct acacgactta
    12541 tccagagcca atttccatat cagagataaa gacaggacaa agatgttcga ttgaggcaga
    12601 aatcgcttcc ccgattcatc taaagactgt tcggaagtta aaactttgta ccgggcttat
    12661 cgcagatgtc agcggacagc tttttgtgcg ctggtttaat atgccatatc ttcgaaatac
    12721 attaaaacag ggagaacggt ggatttttac aggaaccccg atttataaag atggacgtct
    12781 tatgttagaa cagccggagt attgtaagag ggaaaaatat ttgcagttaa tggaaacatt
    12841 tcagccgatt taccctctca caacaggatt gtcgaataag acagtacaaa aagcacaggc
    12901 agctgcattt gaaatgtaca gagaagaaga gtatcttccg gaaaccgttc gaaattatta
    12961 tgatttagaa ccagtgaata cagcacttag agaagtacat tttcctacag ggaccgaaca
    13021 tttgatggag gcgaaaaagc gaatcatttt tgatgaattt ttccgttttt tcagtgcgtt
    13081 agaacttgtc aaagacaggg aggaacaagc actcaatcac tatattattc caatggaaga
    13141 acccgtaaag aggtttgtag aaaatttacc gtatcctctt acaggggcac aaaaaaaggt
    13201 gttaaatgaa attcgccagg acttttccga tacaatggca atgaaccgcc ttttacaggg
    13261 agacgttggt tcgggaaaga cgattgtagc aatgacagcg atgtatgctg ctgttcttgc
    13321 cggttaccaa gcggcgttga tggctccgac agaggtactt gcagaacagc attaccagaa
    13381 ctttgtgaaa ctcctttccc cacttgggat taccgttgcc ctgcttactg gttccacaaa
    13441 agcaaaggaa aaaagagaga taaaggcagc ctgtgcctct ggtgagattc agattttaat
    13501 tggaacgcat acagtgatac aggacgatgt agcttttgac aatcttgcat ttattgttac
    13561 cgatgagcag catcgttttg gagtaaaaca aagagatgcc tttatgaaaa aagggaaaga
    13621 cccccatgtt cttgtaatga gtgcgacgcc gattccacgt acactgggaa ttattttgta
    13681 cagagattta gatgttagca ttatgaatga aatgccggct tccagactgc cgattaaaaa
    13741 ttctgttgtg ggaacttcct atcgtccggc tgcatgggaa tttataagaa agcaggtagc
    13801 acttggacat caggcatatg tgatctgtcc gatgattgag gaaaatgaaa aaatggattt
    13861 ggaaaatgtg gaagagtatg caagaatgct ttcgcaggca ttaccgcctt ctattaccgt
    13921 tgaagcttta aatggacata tgcgcccggc agaaaagaat gatattatgg aacgcttttc
    13981 gaagaatgaa attcagattt tagtttctac taccgttgta gaagtcggta ttgatgttcc
    14041 aaatgcaacc gttatgctca tagagaatgc ggaacggttt ggccttgctc agctccatca
    14101 gctccgcgga cgtgttggaa gaggaaaggc acagtcatac tgtgtcttta tttctggttc
    14161 agaaaaagaa gaagcgatgg aacgtctttc cattatcgga cattctaatg atggatttga
    14221 gattgccaat gaagatttaa aacttcgtgg tccgggagag ttttttggtg taaaacaaag
    14281 tggaacgatg aattttgccc ttggcgatat ttactcgaat gcagatattt taaaaatggc
    14341 ttctgaggca gtggattact taaagaaaga aggatataat ttccagaaat tgcatcagta
    14401 ttctctggag aagaatttga attttgcaaa aaatatttaa aaaccgaatg gaaattgc
//
