## Sun Jul 21 03:53:11 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_958438015.1/GCA_958438015.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_958438015.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_958438015.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
BIFPGKOA_00002	657322.FPR_00390	1.26e-292	831.0	COG4591@1|root,COG4591@2|Bacteria,1UJX6@1239|Firmicutes,24A96@186801|Clostridia	186801|Clostridia	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
BIFPGKOA_00003	221027.JO40_03380	1.09e-64	206.0	COG1136@1|root,COG1136@2|Bacteria,2JA03@203691|Spirochaetes	203691|Spirochaetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BIFPGKOA_00004	657322.FPR_25600	5.09e-203	561.0	COG1082@1|root,COG1082@2|Bacteria,1U81K@1239|Firmicutes,2492P@186801|Clostridia,3WQ0E@541000|Ruminococcaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
BIFPGKOA_00005	657322.FPR_25590	1.53e-163	459.0	28N4D@1|root,2ZB9V@2|Bacteria,1UPRR@1239|Firmicutes,24MJV@186801|Clostridia,3WQCH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00006	657322.FPR_25580	8.49e-157	441.0	2DMDC@1|root,32PHK@2|Bacteria,1V728@1239|Firmicutes,24K2A@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF5058)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5058
BIFPGKOA_00007	657322.FPR_25570	1.9e-112	326.0	COG1357@1|root,COG1357@2|Bacteria,1VC3K@1239|Firmicutes,24I2U@186801|Clostridia,3WKVG@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide_4
BIFPGKOA_00008	657322.FPR_25560	1.72e-108	311.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,3WIXC@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
BIFPGKOA_00009	718252.FP2_17720	4.13e-86	253.0	2ARQN@1|root,31H1Q@2|Bacteria,1V6R0@1239|Firmicutes,24JND@186801|Clostridia,3WKW1@541000|Ruminococcaceae	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
BIFPGKOA_00010	657322.FPR_25540	1.01e-183	513.0	COG4977@1|root,COG4977@2|Bacteria,1UINP@1239|Firmicutes,24PQ6@186801|Clostridia,3WSSR@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
BIFPGKOA_00011	657322.FPR_25530	5.81e-307	838.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,3WHQA@541000|Ruminococcaceae	186801|Clostridia	H	Carbohydrate kinase, FGGY family protein	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
BIFPGKOA_00012	657322.FPR_25520	0.0	878.0	COG4806@1|root,COG4806@2|Bacteria,1TS42@1239|Firmicutes,2487G@186801|Clostridia,3WN5C@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the rhamnose isomerase family	rhaA	-	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
BIFPGKOA_00013	657322.FPR_25510	4.75e-209	576.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia,3WNW2@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
BIFPGKOA_00014	411471.SUBVAR_04806	5.47e-206	579.0	COG2207@1|root,COG2207@2|Bacteria,1UZ0N@1239|Firmicutes,24GNF@186801|Clostridia,3WNMP@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
BIFPGKOA_00015	657322.FPR_25480	1.33e-313	854.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3WHUT@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
BIFPGKOA_00016	657322.FPR_25470	1.02e-222	622.0	COG2211@1|root,COG2211@2|Bacteria,1TSEH@1239|Firmicutes,24EDK@186801|Clostridia,3WNX0@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
BIFPGKOA_00017	657322.FPR_25470	1.99e-102	310.0	COG2211@1|root,COG2211@2|Bacteria,1TSEH@1239|Firmicutes,24EDK@186801|Clostridia,3WNX0@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
BIFPGKOA_00018	657322.FPR_25460	0.0	1448.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,3WNIG@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
BIFPGKOA_00019	657322.FPR_25450	0.0	1236.0	COG3507@1|root,COG3507@2|Bacteria,1TQBJ@1239|Firmicutes,24CFJ@186801|Clostridia,3WNRJ@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
BIFPGKOA_00020	657322.FPR_25440	1.06e-195	543.0	COG1082@1|root,COG1082@2|Bacteria,1TRMY@1239|Firmicutes,24CP4@186801|Clostridia,3WP0G@541000|Ruminococcaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
BIFPGKOA_00021	657322.FPR_25430	0.0	1734.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,249U8@186801|Clostridia,3WHJG@541000|Ruminococcaceae	186801|Clostridia	G	Alpha-L-rhamnosidase N-terminal domain protein	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
BIFPGKOA_00022	657322.FPR_25420	3.37e-271	743.0	COG0738@1|root,COG0738@2|Bacteria,1TPB5@1239|Firmicutes,24913@186801|Clostridia,3WIIJ@541000|Ruminococcaceae	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BIFPGKOA_00023	657322.FPR_25410	0.0	890.0	COG5434@1|root,COG5434@2|Bacteria,1V4PZ@1239|Firmicutes,24CQH@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
BIFPGKOA_00024	657322.FPR_25400	7.94e-290	794.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3WI33@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM
BIFPGKOA_00025	657322.FPR_25390	2.83e-110	318.0	COG3090@1|root,COG3090@2|Bacteria,1TUNV@1239|Firmicutes,25N0I@186801|Clostridia,3WQH9@541000|Ruminococcaceae	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
BIFPGKOA_00026	657322.FPR_25380	3.88e-240	660.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24BWQ@186801|Clostridia,3WRTV@541000|Ruminococcaceae	186801|Clostridia	M	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
BIFPGKOA_00027	1203606.HMPREF1526_02993	3.94e-84	262.0	COG2140@1|root,COG2207@1|root,COG2140@2|Bacteria,COG2207@2|Bacteria,1TPMG@1239|Firmicutes,24ISI@186801|Clostridia,36VKV@31979|Clostridiaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
BIFPGKOA_00029	748224.HMPREF9436_01905	0.0	2004.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3WGCC@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
BIFPGKOA_00030	657322.FPR_25340	0.0	1176.0	COG4289@1|root,COG4289@2|Bacteria,1TSHI@1239|Firmicutes,24C95@186801|Clostridia,3WNAB@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2264)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2264
BIFPGKOA_00031	718252.FP2_29950	1.37e-296	807.0	COG4225@1|root,COG4225@2|Bacteria,1TR4A@1239|Firmicutes,248Z1@186801|Clostridia,3WN7Z@541000|Ruminococcaceae	186801|Clostridia	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
BIFPGKOA_00032	657322.FPR_25320	0.0	1249.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,3WP1V@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
BIFPGKOA_00033	748224.HMPREF9436_01910	2.32e-201	558.0	COG0395@1|root,COG0395@2|Bacteria,1TPIF@1239|Firmicutes,25C5D@186801|Clostridia,3WSB1@541000|Ruminococcaceae	186801|Clostridia	P	Carbohydrate ABC transporter membrane protein 2, CUT1 family	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
BIFPGKOA_00034	748224.HMPREF9436_01911	8.28e-222	611.0	COG1175@1|root,COG1175@2|Bacteria,1TRC0@1239|Firmicutes,25C59@186801|Clostridia,3WJAA@541000|Ruminococcaceae	186801|Clostridia	P	ABC transporter	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
BIFPGKOA_00035	657322.FPR_25290	3.18e-299	818.0	COG1653@1|root,COG1653@2|Bacteria,1TQ6X@1239|Firmicutes,24B3P@186801|Clostridia,3WNQA@541000|Ruminococcaceae	186801|Clostridia	G	Carbohydrate ABC transporter substrate-binding protein, CUT1 family (TC 3.A.1.1.-)	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
BIFPGKOA_00036	657322.FPR_25280	0.0	1195.0	COG2972@1|root,COG2972@2|Bacteria,1TQZM@1239|Firmicutes,247ZV@186801|Clostridia,3WN4N@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
BIFPGKOA_00037	657322.FPR_25270	1.98e-297	812.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TPDP@1239|Firmicutes,24A5I@186801|Clostridia,3WK9T@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
BIFPGKOA_00038	748224.HMPREF9436_01917	0.0	1203.0	COG4225@1|root,COG4225@2|Bacteria,1UXGZ@1239|Firmicutes,25D7M@186801|Clostridia	186801|Clostridia	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
BIFPGKOA_00039	718252.FP2_29870	5.93e-193	535.0	2DBRG@1|root,2ZAKM@2|Bacteria,1UQ8F@1239|Firmicutes,24CHJ@186801|Clostridia,3WN9M@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00040	748224.HMPREF9436_01919	0.0	882.0	2DJT4@1|root,32UDS@2|Bacteria,1VDA1@1239|Firmicutes,24SD3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00041	657322.FPR_25220	6.13e-122	349.0	COG0583@1|root,COG0583@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BIFPGKOA_00042	657322.FPR_15450	0.0	1626.0	COG0433@1|root,COG0433@2|Bacteria,1TQPR@1239|Firmicutes,249UU@186801|Clostridia,3WMCA@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
BIFPGKOA_00044	657322.FPR_15470	7.67e-80	237.0	COG1396@1|root,COG1396@2|Bacteria,1VG9X@1239|Firmicutes,25889@186801|Clostridia,3WM6C@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
BIFPGKOA_00045	657322.FPR_15480	0.0	1769.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,3WKVQ@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR-associated helicase, Cas3	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C
BIFPGKOA_00046	657322.FPR_15490	0.0	1093.0	COG1203@1|root,COG1203@2|Bacteria,1TSVP@1239|Firmicutes,24C2Z@186801|Clostridia	186801|Clostridia	L	CRISPR system CASCADE complex protein CasA	casA	-	-	ko:K19123	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse1
BIFPGKOA_00047	657322.FPR_15500	1.46e-145	410.0	2DP12@1|root,33037@2|Bacteria,1UIAU@1239|Firmicutes,25EFZ@186801|Clostridia,3WQ1R@541000|Ruminococcaceae	186801|Clostridia	S	CRISPR-associated protein Cse2 (CRISPR_cse2)	-	-	-	ko:K19046	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse2
BIFPGKOA_00048	748224.HMPREF9436_01698	5.88e-235	648.0	COG1857@1|root,COG1857@2|Bacteria,1TSM0@1239|Firmicutes,24DJI@186801|Clostridia,3WNUX@541000|Ruminococcaceae	186801|Clostridia	L	CT1975-like protein	casC	-	-	ko:K19124	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CT1975
BIFPGKOA_00049	748224.HMPREF9436_01699	5.04e-154	432.0	2DBXF@1|root,2ZBPB@2|Bacteria,1V2K8@1239|Firmicutes,24H2H@186801|Clostridia,3WPF0@541000|Ruminococcaceae	186801|Clostridia	S	CRISPR-associated protein (Cas_Cas5)	casD	-	-	ko:K19125	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
BIFPGKOA_00050	657322.FPR_15530	1.91e-144	407.0	2DKU6@1|root,30BEK@2|Bacteria,1V5I4@1239|Firmicutes,24HYE@186801|Clostridia,3WPJ9@541000|Ruminococcaceae	186801|Clostridia	S	CRISPR_assoc	casE	-	-	ko:K19126	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_assoc
BIFPGKOA_00051	748224.HMPREF9436_01702	1.17e-16	74.7	COG0847@1|root,COG0847@2|Bacteria,1V0CE@1239|Firmicutes,24AR6@186801|Clostridia,3WQ12@541000|Ruminococcaceae	186801|Clostridia	L	K02342 DNA polymerase III subunit epsilon	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas2CT1978,RNase_T
BIFPGKOA_00052	748224.HMPREF9436_01804	0.0	1393.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3WH5Y@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
BIFPGKOA_00053	657322.FPR_15560	1.49e-155	437.0	COG1410@1|root,COG1410@2|Bacteria,1V7JJ@1239|Firmicutes,24AE1@186801|Clostridia,3WJ7R@541000|Ruminococcaceae	186801|Clostridia	E	Vitamin B12 dependent methionine synthase activation	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
BIFPGKOA_00054	718252.FP2_31820	8.56e-225	633.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WHXB@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
BIFPGKOA_00055	1144310.PMI07_005399	9.84e-05	50.8	COG1396@1|root,COG1396@2|Bacteria,1R6X3@1224|Proteobacteria,2U58N@28211|Alphaproteobacteria,4BIKM@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
BIFPGKOA_00056	411483.FAEPRAA2165_00452	1.25e-22	88.6	COG1476@1|root,COG1476@2|Bacteria,1VMDJ@1239|Firmicutes,24VSX@186801|Clostridia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
BIFPGKOA_00059	546269.HMPREF0389_00175	3e-37	138.0	COG3935@1|root,COG3935@2|Bacteria,1TQT6@1239|Firmicutes,24I78@186801|Clostridia,25SFF@186804|Peptostreptococcaceae	186801|Clostridia	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00060	1203606.HMPREF1526_01325	7.99e-37	144.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,36DTR@31979|Clostridiaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
BIFPGKOA_00063	718252.FP2_30540	1.25e-47	152.0	arCOG06833@1|root,331DJ@2|Bacteria,1VHFU@1239|Firmicutes,24RXW@186801|Clostridia,3WMC7@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00064	397287.C807_01884	1.08e-17	79.0	arCOG07672@1|root,32Z5Y@2|Bacteria,1VG6R@1239|Firmicutes,24T0M@186801|Clostridia,27PVB@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
BIFPGKOA_00066	718252.FP2_17170	2.7e-315	863.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
BIFPGKOA_00067	657322.FPR_25540	8.45e-172	483.0	COG4977@1|root,COG4977@2|Bacteria,1UINP@1239|Firmicutes,24PQ6@186801|Clostridia,3WSSR@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
BIFPGKOA_00068	657322.FPR_25530	6.89e-284	779.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,3WHQA@541000|Ruminococcaceae	186801|Clostridia	H	Carbohydrate kinase, FGGY family protein	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
BIFPGKOA_00069	877414.ATWA01000006_gene97	0.0	889.0	COG2407@1|root,COG2407@2|Bacteria,1UDWP@1239|Firmicutes,24ARY@186801|Clostridia	186801|Clostridia	G	Catalyzes the conversion of L-arabinose to L-ribulose	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_Isome
BIFPGKOA_00070	657322.FPR_25510	3.9e-208	574.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia,3WNW2@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
BIFPGKOA_00071	411483.FAEPRAA2165_01165	1.01e-171	490.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3WIB4@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
BIFPGKOA_00072	718252.FP2_28840	5.38e-150	432.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3WIB4@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
BIFPGKOA_00073	556261.HMPREF0240_03689	2.93e-258	751.0	COG3250@1|root,COG3250@2|Bacteria,1TS9P@1239|Firmicutes,24C3W@186801|Clostridia,36G7E@31979|Clostridiaceae	186801|Clostridia	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
BIFPGKOA_00074	1232446.BAIE02000047_gene300	6.55e-174	503.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,24BTM@186801|Clostridia	186801|Clostridia	G	phosphotransferase system, EIIB	-	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIB,PTS_EIIC
BIFPGKOA_00075	1450694.BTS2_0231	2.09e-61	207.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1V1RQ@1239|Firmicutes,4I2K3@91061|Bacilli,1ZGFJ@1386|Bacillus	91061|Bacilli	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
BIFPGKOA_00078	657322.FPR_12810	5.69e-137	386.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,3WICX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	KatE	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00079	657322.FPR_12800	0.0	1267.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WNVD@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
BIFPGKOA_00080	657322.FPR_12790	5.44e-176	490.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3WHVP@541000|Ruminococcaceae	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BIFPGKOA_00081	657322.FPR_12780	2.3e-185	515.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,3WJ55@541000|Ruminococcaceae	186801|Clostridia	GM	Transport permease protein	pyrL	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
BIFPGKOA_00082	748224.HMPREF9436_02154	7.45e-140	394.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,3WIH5@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
BIFPGKOA_00083	657322.FPR_12760	2.4e-312	852.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WJ4Y@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB_3	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	CW_binding_1,PBP5_C,Peptidase_S11
BIFPGKOA_00084	657322.FPR_12750	7.84e-133	377.0	COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,24HE6@186801|Clostridia,3WHFH@541000|Ruminococcaceae	186801|Clostridia	H	Dipicolinic acid synthetase, B subunit	spoVFB	-	-	ko:K06411	-	-	-	-	ko00000	-	-	-	Flavoprotein
BIFPGKOA_00085	657322.FPR_12740	1.98e-166	468.0	COG0111@1|root,COG0111@2|Bacteria,1TPUC@1239|Firmicutes,253BG@186801|Clostridia,3WJ87@541000|Ruminococcaceae	186801|Clostridia	EH	dipicolinic acid synthetase, A subunit	spoVFA	-	-	ko:K06410	-	-	-	-	ko00000	-	-	-	2-Hacid_dh_C,AlaDh_PNT_C,DpaA_N
BIFPGKOA_00086	748224.HMPREF9436_01370	0.0	1215.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3WST3@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg,SBP_bac_3,SnoaL_3
BIFPGKOA_00087	748224.HMPREF9436_01369	4.78e-131	379.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3WH7X@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
BIFPGKOA_00088	657322.FPR_12710	0.0	1392.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3WHN6@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HATPase_c,HD,HD_5,Response_reg
BIFPGKOA_00090	657322.FPR_12680	1.03e-303	828.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
BIFPGKOA_00091	657322.FPR_12670	0.0	897.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WH49@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_00092	657322.FPR_12660	2.36e-254	702.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,3WI31@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type branched-chain amino acid transport systems periplasmic component	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
BIFPGKOA_00093	657322.FPR_12650	3.12e-193	538.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,3WGTF@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
BIFPGKOA_00094	657322.FPR_12640	1.18e-229	634.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,3WHKQ@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
BIFPGKOA_00095	657322.FPR_12630	1.3e-199	553.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,3WH2I@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type branched-chain amino acid transport systems ATPase component	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
BIFPGKOA_00096	657322.FPR_12620	5.4e-162	454.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,3WHG1@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter, ATP-binding protein	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
BIFPGKOA_00097	657322.FPR_12610	6.3e-252	690.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia,3WHV3@541000|Ruminococcaceae	186801|Clostridia	E	aspartate-ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
BIFPGKOA_00098	657322.FPR_12600	1e-218	603.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,25B4M@186801|Clostridia,3WRIV@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
BIFPGKOA_00099	657322.FPR_12590	0.0	872.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3WGUF@541000|Ruminococcaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
BIFPGKOA_00100	657322.FPR_12580	2.48e-39	131.0	COG4224@1|root,COG4224@2|Bacteria,1TUAX@1239|Firmicutes,24QS9@186801|Clostridia,3WMRQ@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF896)	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
BIFPGKOA_00101	657322.FPR_12570	1.59e-150	422.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia,3WGWP@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
BIFPGKOA_00102	657322.FPR_12560	3.35e-250	689.0	COG0738@1|root,COG0738@2|Bacteria,1UZWI@1239|Firmicutes,24H3U@186801|Clostridia,3WMSR@541000|Ruminococcaceae	186801|Clostridia	G	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BIFPGKOA_00103	657322.FPR_12550	9.52e-286	780.0	COG1020@1|root,COG1020@2|Bacteria,1VIM0@1239|Firmicutes,24UTC@186801|Clostridia,3WMHY@541000|Ruminococcaceae	186801|Clostridia	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00104	748224.HMPREF9436_02192	8e-42	139.0	COG0236@1|root,COG0236@2|Bacteria,1VMEW@1239|Firmicutes,24WDM@186801|Clostridia	186801|Clostridia	IQ	Acyl carrier protein	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
BIFPGKOA_00105	657322.FPR_12530	0.0	995.0	COG1022@1|root,COG1022@2|Bacteria,1V0YG@1239|Firmicutes,24IFY@186801|Clostridia,3WRIU@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
BIFPGKOA_00106	657322.FPR_12520	1.05e-274	750.0	COG3594@1|root,COG3594@2|Bacteria,1VEEI@1239|Firmicutes,24UA2@186801|Clostridia,3WR41@541000|Ruminococcaceae	186801|Clostridia	G	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
BIFPGKOA_00108	657322.FPR_12500	0.0	1050.0	COG0438@1|root,COG0438@2|Bacteria,1V8AN@1239|Firmicutes,24IIP@186801|Clostridia	186801|Clostridia	M	Glycosyl-transferase family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_5,Glycos_transf_1
BIFPGKOA_00109	657322.FPR_12490	3.41e-235	648.0	COG0392@1|root,COG0392@2|Bacteria,1V2TI@1239|Firmicutes,24K1U@186801|Clostridia	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
BIFPGKOA_00111	657322.FPR_19680	3.17e-111	319.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,3WHNP@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
BIFPGKOA_00112	657322.FPR_19670	1.02e-81	242.0	2D04F@1|root,32T7R@2|Bacteria,1VBXI@1239|Firmicutes,24N5C@186801|Clostridia,3WK16@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2500
BIFPGKOA_00113	657322.FPR_19660	3.32e-74	222.0	2CTED@1|root,32ST9@2|Bacteria,1VD31@1239|Firmicutes,24Q04@186801|Clostridia,3WM4U@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00114	657322.FPR_19650	9.14e-88	257.0	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,24MVS@186801|Clostridia,3WKPB@541000|Ruminococcaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
BIFPGKOA_00115	657322.FPR_19640	1.57e-190	528.0	COG0561@1|root,COG0561@2|Bacteria,1V43V@1239|Firmicutes,24AQQ@186801|Clostridia,3WJFW@541000|Ruminococcaceae	186801|Clostridia	S	HAD hydrolase, family IIB	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
BIFPGKOA_00116	657322.FPR_19630	2.69e-195	542.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia,3WSC5@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
BIFPGKOA_00117	1268072.PSAB_22635	0.000822	48.9	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4IS5F@91061|Bacilli,2772D@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	sasA	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
BIFPGKOA_00120	657322.FPR_19580	0.0	1883.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3WGE7@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
BIFPGKOA_00121	657322.FPR_19570	1.39e-192	535.0	COG0566@1|root,COG0566@2|Bacteria,1TSUW@1239|Firmicutes,24ACK@186801|Clostridia,3WGSS@541000|Ruminococcaceae	186801|Clostridia	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
BIFPGKOA_00123	411483.FAEPRAA2165_03131	4.93e-35	152.0	COG4886@1|root,COG4886@2|Bacteria,1V3DU@1239|Firmicutes,24GSD@186801|Clostridia,3WK0Z@541000|Ruminococcaceae	186801|Clostridia	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,LRR_4
BIFPGKOA_00124	748224.HMPREF9436_00767	2.28e-278	794.0	COG4886@1|root,COG4886@2|Bacteria,1V3DU@1239|Firmicutes,24GSD@186801|Clostridia,3WK0Z@541000|Ruminococcaceae	186801|Clostridia	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,LRR_4
BIFPGKOA_00125	748224.HMPREF9436_00541	0.0	995.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,3WIIN@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45	ko:K01119,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
BIFPGKOA_00126	748224.HMPREF9436_00540	1.66e-246	678.0	2A16U@1|root,30PCV@2|Bacteria,1UQIU@1239|Firmicutes,258AC@186801|Clostridia,3WMB4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00128	657322.FPR_07830	8.37e-136	383.0	2A1UJ@1|root,30Q3Q@2|Bacteria,1V50E@1239|Firmicutes,24ITX@186801|Clostridia,3WJ9S@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00130	748224.HMPREF9436_00536	2.23e-165	466.0	COG1512@1|root,COG1512@2|Bacteria,1V2US@1239|Firmicutes,25CUP@186801|Clostridia,3WJ66@541000|Ruminococcaceae	186801|Clostridia	S	Pfam:TPM	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
BIFPGKOA_00131	748224.HMPREF9436_00535	4.94e-269	735.0	COG1996@1|root,COG1996@2|Bacteria,1UI9I@1239|Firmicutes,248XK@186801|Clostridia,3WHNV@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00133	748224.HMPREF9436_00533	1.36e-210	581.0	2DT94@1|root,33J9A@2|Bacteria,1W4B6@1239|Firmicutes,256YX@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4428
BIFPGKOA_00134	657322.FPR_07770	4.41e-296	813.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3WHZY@541000|Ruminococcaceae	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,SHOCT
BIFPGKOA_00137	411483.FAEPRAA2165_03118	0.0	878.0	2EJ3B@1|root,33CUJ@2|Bacteria,1VZS4@1239|Firmicutes,253ZC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00138	748224.HMPREF9436_00597	0.0	969.0	2EJ3B@1|root,33CUJ@2|Bacteria,1VZS4@1239|Firmicutes,253ZC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00142	748224.HMPREF9436_00591	0.0	886.0	COG1653@1|root,COG1653@2|Bacteria,1TRST@1239|Firmicutes,24APZ@186801|Clostridia	186801|Clostridia	G	COG COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
BIFPGKOA_00143	748224.HMPREF9436_00590	0.0	961.0	COG2197@1|root,COG2197@2|Bacteria,1UYM1@1239|Firmicutes,2497D@186801|Clostridia	186801|Clostridia	KT	transcriptional regulator LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
BIFPGKOA_00144	748224.HMPREF9436_01339	1.44e-25	104.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,3WGZ4@541000|Ruminococcaceae	186801|Clostridia	GM	Polysaccharide biosynthesis protein	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
BIFPGKOA_00145	657322.FPR_21430	0.0	871.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,3WHCB@541000|Ruminococcaceae	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
BIFPGKOA_00147	748224.HMPREF9436_00886	1.28e-155	443.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3WH9Z@541000|Ruminococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
BIFPGKOA_00148	657322.FPR_21460	5.69e-100	290.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia,3WKQY@541000|Ruminococcaceae	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
BIFPGKOA_00149	748224.HMPREF9436_00889	0.0	1239.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,3WGCV@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain protein	apu	-	2.4.1.25,3.2.1.133,3.2.1.135,3.2.1.20,3.2.1.54	ko:K00705,ko:K01187,ko:K01208	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R02112,R03122,R05196,R06087,R06088,R11262	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH13,GH31,GH77	-	Alpha-amylase,Alpha-amylase_N,Glyco_hydro_77,Malt_amylase_C
BIFPGKOA_00150	657322.FPR_21480	0.0	1606.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WHEI@541000|Ruminococcaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
BIFPGKOA_00151	657322.FPR_21490	1.52e-68	211.0	COG3027@1|root,COG3027@2|Bacteria,1VGM3@1239|Firmicutes,24T2P@186801|Clostridia,3WM0A@541000|Ruminococcaceae	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
BIFPGKOA_00152	657322.FPR_21500	0.0	1326.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,3WH8K@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase U32	ydcP	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
BIFPGKOA_00153	657322.FPR_21510	6.48e-99	287.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,3WK0P@541000|Ruminococcaceae	186801|Clostridia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
BIFPGKOA_00154	657322.FPR_21520	5.2e-132	374.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3WJIZ@541000|Ruminococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
BIFPGKOA_00155	657322.FPR_21530	1.63e-235	649.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,3WGF8@541000|Ruminococcaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
BIFPGKOA_00156	748224.HMPREF9436_00897	4.03e-162	459.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,3WIMD@541000|Ruminococcaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
BIFPGKOA_00157	657322.FPR_21550	6.63e-122	348.0	2EJZS@1|root,33DQA@2|Bacteria,1VHWG@1239|Firmicutes,24STU@186801|Clostridia,3WMHW@541000|Ruminococcaceae	186801|Clostridia	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
BIFPGKOA_00158	657322.FPR_21560	0.0	1428.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,3WGCH@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
BIFPGKOA_00159	657322.FPR_21570	4.06e-93	271.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3WII3@541000|Ruminococcaceae	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
BIFPGKOA_00160	657322.FPR_21580	6.31e-117	335.0	COG0482@1|root,COG0482@2|Bacteria	2|Bacteria	J	sulfurtransferase activity	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
BIFPGKOA_00161	657322.FPR_21590	1.7e-115	330.0	COG0328@1|root,COG0328@2|Bacteria,1V4A0@1239|Firmicutes,24FSS@186801|Clostridia,3WISH@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
BIFPGKOA_00162	657322.FPR_21610	0.0	1187.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3WH9M@541000|Ruminococcaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
BIFPGKOA_00163	657322.FPR_21620	0.0	1267.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,3WH8C@541000|Ruminococcaceae	186801|Clostridia	T	domain protein	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
BIFPGKOA_00164	657322.FPR_21630	2.11e-272	744.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,3WHCZ@541000|Ruminococcaceae	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
BIFPGKOA_00165	657322.FPR_21640	1.51e-94	276.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,3WJCC@541000|Ruminococcaceae	186801|Clostridia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
BIFPGKOA_00166	657322.FPR_21650	0.0	903.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WH8B@541000|Ruminococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
BIFPGKOA_00167	657322.FPR_21660	0.0	910.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,3WHDC@541000|Ruminococcaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
BIFPGKOA_00168	657322.FPR_21670	7.11e-124	353.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,3WIX7@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
BIFPGKOA_00169	411483.FAEPRAA2165_02390	4.6e-72	217.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,3WJ8U@541000|Ruminococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
BIFPGKOA_00170	657322.FPR_31330	5.85e-128	363.0	COG0681@1|root,COG0681@2|Bacteria,1V6R3@1239|Firmicutes,25CN6@186801|Clostridia,3WKCK@541000|Ruminococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
BIFPGKOA_00171	657322.FPR_31320	6.04e-219	604.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,3WGB7@541000|Ruminococcaceae	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
BIFPGKOA_00172	657322.FPR_31310	8.1e-153	429.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,3WIMJ@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
BIFPGKOA_00173	657322.FPR_31300	1.94e-83	246.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,3WMJ4@541000|Ruminococcaceae	186801|Clostridia	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
BIFPGKOA_00174	657322.FPR_31290	0.0	941.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3WGWF@541000|Ruminococcaceae	186801|Clostridia	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
BIFPGKOA_00175	748224.HMPREF9436_01496	3.41e-160	449.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,249BN@186801|Clostridia,3WIIA@541000|Ruminococcaceae	186801|Clostridia	S	Ser Thr phosphatase family protein	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
BIFPGKOA_00176	657322.FPR_31270	9.41e-296	809.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
BIFPGKOA_00177	748224.HMPREF9436_01499	3.59e-134	380.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,3WGQP@541000|Ruminococcaceae	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
BIFPGKOA_00178	657322.FPR_31250	1.89e-316	862.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WGYG@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
BIFPGKOA_00179	657322.FPR_31240	0.0	870.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,3WGVJ@541000|Ruminococcaceae	186801|Clostridia	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
BIFPGKOA_00180	657322.FPR_31230	0.0	1446.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,3WGN7@541000|Ruminococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
BIFPGKOA_00181	657322.FPR_31220	7.46e-106	305.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3WJ07@541000|Ruminococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
BIFPGKOA_00183	657322.FPR_31200	9.98e-150	422.0	COG2323@1|root,COG2323@2|Bacteria,1V3NW@1239|Firmicutes,24H1Q@186801|Clostridia,3WJ0A@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
BIFPGKOA_00184	657322.FPR_31190	0.0	911.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,3WHDF@541000|Ruminococcaceae	186801|Clostridia	EG	spore germination protein	-	-	-	ko:K06295	-	-	-	-	ko00000	-	-	-	GerA
BIFPGKOA_00187	657322.FPR_31160	1.85e-316	862.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WGB6@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
BIFPGKOA_00188	657322.FPR_31150	2.39e-156	439.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia,3WI7X@541000|Ruminococcaceae	186801|Clostridia	K	Response regulator receiver domain protein	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
BIFPGKOA_00189	657322.FPR_31140	0.0	1113.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3WGTX@541000|Ruminococcaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
BIFPGKOA_00190	657322.FPR_31130	3.35e-218	602.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,3WGB3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
BIFPGKOA_00191	657322.FPR_31120	9.49e-207	572.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3WGX6@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
BIFPGKOA_00192	748224.HMPREF9436_01517	4.38e-186	519.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,3WGDD@541000|Ruminococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
BIFPGKOA_00193	657322.FPR_31090	7.3e-217	599.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,3WHUA@541000|Ruminococcaceae	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
BIFPGKOA_00195	657322.FPR_17730	0.0	1000.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,3WSMC@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
BIFPGKOA_00196	657322.FPR_17720	9.8e-167	466.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,3WGB8@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
BIFPGKOA_00197	1121115.AXVN01000079_gene2738	4.8e-106	315.0	2BYUU@1|root,2Z7P3@2|Bacteria,1UYDK@1239|Firmicutes,249UN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00198	457412.RSAG_02085	8.72e-73	226.0	2C0W2@1|root,306ZY@2|Bacteria,1V5YY@1239|Firmicutes,24I0Q@186801|Clostridia,3WMI1@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_7,MqsA_antitoxin
BIFPGKOA_00199	693746.OBV_31850	8.43e-157	446.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,2N8HA@216572|Oscillospiraceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
BIFPGKOA_00200	1029718.SFBM_0696	2.53e-306	853.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,36DI9@31979|Clostridiaceae	186801|Clostridia	G	Pts system	-	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
BIFPGKOA_00201	1029718.SFBM_0697	7.61e-307	840.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,36DZU@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	bglC	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
BIFPGKOA_00202	1449050.JNLE01000003_gene3691	4.35e-123	360.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,24931@186801|Clostridia,36H6I@31979|Clostridiaceae	186801|Clostridia	K	CAT RNA binding domain	-	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
BIFPGKOA_00203	1045858.Bint_0934	4.1e-93	279.0	COG2364@1|root,COG2364@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00205	657322.FPR_01740	2.11e-221	610.0	28HEE@1|root,2Z7QU@2|Bacteria,1TVQR@1239|Firmicutes,248QB@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF932
BIFPGKOA_00207	748224.HMPREF9436_00563	7e-215	594.0	COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,249SB@186801|Clostridia,3WKYR@541000|Ruminococcaceae	186801|Clostridia	L	YqaJ viral recombinase family	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
BIFPGKOA_00208	657322.FPR_15180	2.19e-60	191.0	2B9XI@1|root,323AV@2|Bacteria,1V7VV@1239|Firmicutes,24QYY@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1071
BIFPGKOA_00210	742735.HMPREF9467_03110	3.69e-13	66.2	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,24MDN@186801|Clostridia,221HQ@1506553|Lachnoclostridium	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
BIFPGKOA_00211	665956.HMPREF1032_03348	1.51e-189	537.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24B23@186801|Clostridia,3WID1@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
BIFPGKOA_00212	657322.FPR_17670	2.19e-270	740.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,3WG9I@541000|Ruminococcaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
BIFPGKOA_00213	748224.HMPREF9436_00443	1.18e-151	427.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,3WI24@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
BIFPGKOA_00214	657322.FPR_17650	0.0	1165.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WG9Y@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
BIFPGKOA_00215	657322.FPR_17640	1.68e-45	147.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24QS3@186801|Clostridia,3WKYW@541000|Ruminococcaceae	186801|Clostridia	C	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
BIFPGKOA_00216	411483.FAEPRAA2165_00122	1.71e-61	190.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3WK18@541000|Ruminococcaceae	186801|Clostridia	K	regulatory protein, arsR	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
BIFPGKOA_00217	657322.FPR_17620	2.39e-85	251.0	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,3WKXN@541000|Ruminococcaceae	186801|Clostridia	S	thioesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
BIFPGKOA_00219	657322.FPR_17600	0.0	1022.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,3WGRM@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
BIFPGKOA_00220	748224.HMPREF9436_02136	3.54e-98	286.0	COG1846@1|root,COG1846@2|Bacteria,1V6UN@1239|Firmicutes,24JGS@186801|Clostridia,3WIVE@541000|Ruminococcaceae	186801|Clostridia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR
BIFPGKOA_00221	657322.FPR_17580	7.5e-86	253.0	COG2510@1|root,COG2510@2|Bacteria,1V3VG@1239|Firmicutes,247SX@186801|Clostridia,3WGSZ@541000|Ruminococcaceae	186801|Clostridia	S	EamA-like transporter family	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
BIFPGKOA_00222	657322.FPR_24700	3.51e-248	683.0	COG1589@1|root,COG1589@2|Bacteria,1UHVF@1239|Firmicutes,25E4A@186801|Clostridia,3WIXM@541000|Ruminococcaceae	186801|Clostridia	M	Putative stage IV sporulation protein YqfD	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
BIFPGKOA_00223	748224.HMPREF9436_01053	5.56e-195	543.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,3WHW9@541000|Ruminococcaceae	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
BIFPGKOA_00224	657322.FPR_24670	4.33e-183	508.0	COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,25E3F@186801|Clostridia,3WIFZ@541000|Ruminococcaceae	186801|Clostridia	Q	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
BIFPGKOA_00225	657322.FPR_24660	1.72e-142	402.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,3WH1B@541000|Ruminococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
BIFPGKOA_00226	657322.FPR_24650	0.0	1569.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3WH4M@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
BIFPGKOA_00227	657322.FPR_24640	3.37e-117	336.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia,3WK8P@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
BIFPGKOA_00228	657322.FPR_24630	0.0	1218.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3WGHX@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
BIFPGKOA_00229	657322.FPR_24620	3.97e-173	483.0	COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes,24HKY@186801|Clostridia,3WJVM@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
BIFPGKOA_00231	657322.FPR_24600	0.0	971.0	COG2755@1|root,COG2755@2|Bacteria,1VG8J@1239|Firmicutes,24RJ2@186801|Clostridia,3WNI1@541000|Ruminococcaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,Lipase_GDSL_2
BIFPGKOA_00232	748224.HMPREF9436_01043	7.2e-130	372.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,3WITI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
BIFPGKOA_00233	657322.FPR_24580	2.71e-72	217.0	2E9SM@1|root,333YT@2|Bacteria,1VNW8@1239|Firmicutes,25BUJ@186801|Clostridia,3WS91@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00234	657322.FPR_24570	7.41e-65	197.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,3WKB9@541000|Ruminococcaceae	186801|Clostridia	S	protein, YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
BIFPGKOA_00235	657322.FPR_24560	0.0	1097.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,3WGHR@541000|Ruminococcaceae	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
BIFPGKOA_00236	657322.FPR_24550	3.56e-168	469.0	COG1073@1|root,COG1073@2|Bacteria,1U9AI@1239|Firmicutes,24B6Z@186801|Clostridia,3WJ56@541000|Ruminococcaceae	186801|Clostridia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	-
BIFPGKOA_00237	657322.FPR_24540	2.13e-276	757.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia,3WH3E@541000|Ruminococcaceae	186801|Clostridia	C	decarboxylase beta subunit	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
BIFPGKOA_00238	657322.FPR_24530	1.8e-59	185.0	2ECK3@1|root,336I7@2|Bacteria,1VG26@1239|Firmicutes	1239|Firmicutes	C	decarboxylase gamma	-	-	-	-	-	-	-	-	-	-	-	-	OAD_gamma
BIFPGKOA_00239	657322.FPR_24520	9.51e-240	659.0	COG1077@1|root,COG1077@2|Bacteria,1U7BF@1239|Firmicutes,24CEA@186801|Clostridia,3WI36@541000|Ruminococcaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
BIFPGKOA_00240	748224.HMPREF9436_01318	0.0	1340.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,3WGP3@541000|Ruminococcaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
BIFPGKOA_00241	657322.FPR_24500	7.75e-233	641.0	COG3081@1|root,COG3081@2|Bacteria,1TSR5@1239|Firmicutes,25CG3@186801|Clostridia,3WKKZ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	NA37
BIFPGKOA_00242	657322.FPR_24490	4.74e-196	546.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,25CBA@186801|Clostridia,3WSC0@541000|Ruminococcaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
BIFPGKOA_00244	657322.FPR_30240	5.65e-138	394.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,3WGGY@541000|Ruminococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
BIFPGKOA_00245	657322.FPR_30250	5.72e-151	424.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3WJUT@541000|Ruminococcaceae	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
BIFPGKOA_00246	657322.FPR_30270	0.0	973.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,3WHVR@541000|Ruminococcaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
BIFPGKOA_00247	748224.HMPREF9436_01538	0.0	1214.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WGTP@541000|Ruminococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
BIFPGKOA_00248	1476973.JMMB01000007_gene957	2.27e-26	113.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,25R76@186804|Peptostreptococcaceae	186801|Clostridia	S	ATPases associated with a variety of cellular activities	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
BIFPGKOA_00250	657322.FPR_30310	1.78e-30	108.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,3WKGF@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
BIFPGKOA_00252	657322.FPR_30330	3.18e-239	659.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia,3WJA7@541000|Ruminococcaceae	186801|Clostridia	S	Stage III sporulation protein AE (spore_III_AE)	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
BIFPGKOA_00254	748224.HMPREF9436_01545	7.24e-62	196.0	2E6BB@1|root,32FH3@2|Bacteria,1V7J4@1239|Firmicutes,24J8Z@186801|Clostridia,3WKIY@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
BIFPGKOA_00255	657322.FPR_30360	4.33e-119	343.0	2E3US@1|root,32YS3@2|Bacteria,1VESK@1239|Firmicutes,24R9H@186801|Clostridia,3WITN@541000|Ruminococcaceae	186801|Clostridia	S	SpoIIIAH-like protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
BIFPGKOA_00256	657322.FPR_30370	1.29e-74	224.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,3WKSG@541000|Ruminococcaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
BIFPGKOA_00257	657322.FPR_30380	5.55e-100	290.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,3WK9U@541000|Ruminococcaceae	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
BIFPGKOA_00258	748224.HMPREF9436_01550	5.47e-209	579.0	COG0533@1|root,COG0533@2|Bacteria,1TRPY@1239|Firmicutes,24CN4@186801|Clostridia,3WG7R@541000|Ruminococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	gcp1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
BIFPGKOA_00259	748224.HMPREF9436_01551	8.54e-211	592.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,3WGCP@541000|Ruminococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
BIFPGKOA_00260	657322.FPR_30410	1.16e-34	119.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,256ZU@186801|Clostridia,3WR05@541000|Ruminococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
BIFPGKOA_00261	657322.FPR_30420	2.31e-200	556.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,3WINP@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
BIFPGKOA_00262	657322.FPR_30430	1.39e-101	295.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,24MV7@186801|Clostridia,3WJXW@541000|Ruminococcaceae	186801|Clostridia	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
BIFPGKOA_00263	657322.FPR_30440	0.0	1269.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3WGVF@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
BIFPGKOA_00264	748224.HMPREF9436_01556	2.54e-175	490.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3WGGG@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
BIFPGKOA_00265	657322.FPR_30460	3.18e-202	560.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,3WHYS@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
BIFPGKOA_00266	657322.FPR_30470	6.8e-110	316.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,3WJZ0@541000|Ruminococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
BIFPGKOA_00267	657322.FPR_30480	0.0	991.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3WHDP@541000|Ruminococcaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
BIFPGKOA_00268	657322.FPR_30490	1.1e-296	809.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3WHP7@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
BIFPGKOA_00269	657322.FPR_30500	2.36e-130	370.0	COG2190@1|root,COG2190@2|Bacteria,1W092@1239|Firmicutes,25EGH@186801|Clostridia,3WSQZ@541000|Ruminococcaceae	186801|Clostridia	G	PTS system	ptbA	-	-	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1
BIFPGKOA_00270	657322.FPR_30510	1.9e-99	289.0	COG0527@1|root,COG0527@2|Bacteria,1V6AQ@1239|Firmicutes,24PYP@186801|Clostridia,3WKNF@541000|Ruminococcaceae	186801|Clostridia	E	ACT domain	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_7
BIFPGKOA_00271	657322.FPR_20660	6.54e-157	441.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,3WGM5@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
BIFPGKOA_00272	748224.HMPREF9436_02912	6e-105	313.0	2APHA@1|root,31EK9@2|Bacteria,1VIZ2@1239|Firmicutes,258XE@186801|Clostridia,3WKUY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U4
BIFPGKOA_00274	657322.FPR_20700	0.0	1253.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,3WH2R@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
BIFPGKOA_00275	657322.FPR_20710	5.25e-72	217.0	COG5341@1|root,COG5341@2|Bacteria,1VII9@1239|Firmicutes,24SGZ@186801|Clostridia,3WQHY@541000|Ruminococcaceae	186801|Clostridia	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
BIFPGKOA_00276	657322.FPR_20720	6.57e-297	822.0	COG1316@1|root,COG4223@1|root,COG1316@2|Bacteria,COG4223@2|Bacteria,1TR1B@1239|Firmicutes,24AAY@186801|Clostridia,3WJ6Y@541000|Ruminococcaceae	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNA_PPF,LytR_cpsA_psr,NMT1
BIFPGKOA_00277	657322.FPR_20730	1.3e-211	585.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,3WI75@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
BIFPGKOA_00278	748224.HMPREF9436_00932	2.71e-308	857.0	COG3583@1|root,COG4942@1|root,COG3583@2|Bacteria,COG4942@2|Bacteria,1UK5Q@1239|Firmicutes,25FKW@186801|Clostridia	186801|Clostridia	D	G5	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
BIFPGKOA_00279	657322.FPR_20750	2.49e-168	470.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,3WHNA@541000|Ruminococcaceae	186801|Clostridia	F	purine-nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
BIFPGKOA_00280	657322.FPR_20760	1.07e-98	287.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,3WK22@541000|Ruminococcaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
BIFPGKOA_00281	657322.FPR_20770	1.13e-255	704.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,3WJKQ@541000|Ruminococcaceae	186801|Clostridia	S	basic membrane	tmpC	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
BIFPGKOA_00282	748224.HMPREF9436_00937	0.0	946.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3WSIS@541000|Ruminococcaceae	186801|Clostridia	S	transport systems ATPase components	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
BIFPGKOA_00283	657322.FPR_20790	2.38e-255	703.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3WHM5@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
BIFPGKOA_00284	657322.FPR_20800	1.05e-202	563.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,3WHCN@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
BIFPGKOA_00285	657322.FPR_20810	2.72e-134	384.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,3WJVW@541000|Ruminococcaceae	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
BIFPGKOA_00286	657322.FPR_20820	3.27e-158	446.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,3WI2V@541000|Ruminococcaceae	186801|Clostridia	D	Capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,ParA,Wzz
BIFPGKOA_00287	657322.FPR_20830	8.08e-184	510.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia,3WK04@541000|Ruminococcaceae	186801|Clostridia	GM	capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
BIFPGKOA_00288	657322.FPR_20840	1.73e-123	359.0	2BCB7@1|root,325WH@2|Bacteria,1VU5S@1239|Firmicutes	657322.FPR_20840|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00289	657322.FPR_20850	2.13e-202	562.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WIHH@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
BIFPGKOA_00290	748224.HMPREF9436_02963	3.81e-285	790.0	COG4166@1|root,COG4166@2|Bacteria,1VRU1@1239|Firmicutes,255ES@186801|Clostridia,3WIM7@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter, substrate-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
BIFPGKOA_00292	657322.FPR_29420	1.63e-280	767.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5,Lactamase_B
BIFPGKOA_00293	657322.FPR_29410	1.49e-268	741.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,3WHCS@541000|Ruminococcaceae	186801|Clostridia	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
BIFPGKOA_00294	718252.FP2_18630	7.11e-224	632.0	COG1305@1|root,COG1305@2|Bacteria,1TT33@1239|Firmicutes,24B27@186801|Clostridia,3WPMU@541000|Ruminococcaceae	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
BIFPGKOA_00295	657322.FPR_29380	8.13e-264	721.0	COG0657@1|root,COG0657@2|Bacteria,1U1GT@1239|Firmicutes,24E51@186801|Clostridia,3WM2Q@541000|Ruminococcaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
BIFPGKOA_00296	657322.FPR_29370	5.96e-127	360.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24KJU@186801|Clostridia	186801|Clostridia	M	acetyltransferase (GNAT) family	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
BIFPGKOA_00297	657322.FPR_29360	9.87e-127	360.0	COG1896@1|root,COG1896@2|Bacteria,1UIAE@1239|Firmicutes,25EFH@186801|Clostridia,3WSPD@541000|Ruminococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
BIFPGKOA_00298	657322.FPR_29350	9e-100	289.0	2FDXA@1|root,345XQ@2|Bacteria,1VYRW@1239|Firmicutes,253D4@186801|Clostridia,3WQHI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00299	657322.FPR_29340	4e-188	522.0	COG0657@1|root,COG0657@2|Bacteria,1TP1H@1239|Firmicutes,24D7F@186801|Clostridia,3WIZJ@541000|Ruminococcaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
BIFPGKOA_00300	657322.FPR_29330	1e-109	316.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24J98@186801|Clostridia,3WJY6@541000|Ruminococcaceae	186801|Clostridia	S	TIGRFAM C_GCAxxG_C_C family	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
BIFPGKOA_00301	657322.FPR_29320	0.0	1231.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,3WGY6@541000|Ruminococcaceae	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
BIFPGKOA_00302	657322.FPR_29310	1.09e-254	699.0	COG2433@1|root,COG2433@2|Bacteria,1UK5K@1239|Firmicutes,25FKU@186801|Clostridia,3WSNW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
BIFPGKOA_00303	657322.FPR_29300	3.52e-311	847.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3WHNU@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
BIFPGKOA_00304	748224.HMPREF9436_03022	0.0	971.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3WGYV@541000|Ruminococcaceae	186801|Clostridia	G	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
BIFPGKOA_00305	657322.FPR_29280	2.66e-171	479.0	COG3142@1|root,COG3142@2|Bacteria,1UYI8@1239|Firmicutes,247QB@186801|Clostridia,3WIQQ@541000|Ruminococcaceae	186801|Clostridia	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
BIFPGKOA_00306	657322.FPR_29270	0.0	943.0	COG2898@1|root,COG2898@2|Bacteria,1U5FR@1239|Firmicutes,248XI@186801|Clostridia,3WIHF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
BIFPGKOA_00307	657322.FPR_29260	3.15e-171	478.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia,3WH0B@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BIFPGKOA_00308	411483.FAEPRAA2165_01843	5.03e-254	711.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
BIFPGKOA_00309	657322.FPR_05160	2.3e-145	416.0	COG3266@1|root,COG3266@2|Bacteria,1USV4@1239|Firmicutes,24VT3@186801|Clostridia	186801|Clostridia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00310	657322.FPR_05150	4.65e-194	539.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,3WGVX@541000|Ruminococcaceae	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
BIFPGKOA_00311	657322.FPR_05140	0.0	1051.0	COG4932@1|root,COG4932@2|Bacteria,1UXYC@1239|Firmicutes,24GBW@186801|Clostridia,3WKET@541000|Ruminococcaceae	186801|Clostridia	M	Gram-positive pilin backbone subunit 2, Cna-B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	GramPos_pilinBB,Gram_pos_anchor
BIFPGKOA_00312	657322.FPR_05130	0.0	3105.0	COG0810@1|root,COG0810@2|Bacteria,1VPVI@1239|Firmicutes,258U0@186801|Clostridia,3WNQ8@541000|Ruminococcaceae	186801|Clostridia	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	FctA
BIFPGKOA_00313	657322.FPR_05120	2.17e-134	381.0	COG0681@1|root,COG0681@2|Bacteria,1V542@1239|Firmicutes,24I8N@186801|Clostridia,3WIUD@541000|Ruminococcaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
BIFPGKOA_00314	657322.FPR_05110	4.76e-70	217.0	2EMVY@1|root,31QVD@2|Bacteria,1TV7K@1239|Firmicutes,259W4@186801|Clostridia,3WQSZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00316	748224.HMPREF9436_02799	1.73e-46	156.0	COG5263@1|root,COG5263@2|Bacteria,1VFMJ@1239|Firmicutes,24T8X@186801|Clostridia	186801|Clostridia	S	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Flg_new
BIFPGKOA_00318	657322.FPR_05080	5.88e-164	459.0	COG1802@1|root,COG1802@2|Bacteria,1V90H@1239|Firmicutes,24B32@186801|Clostridia,3WQIB@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K22293	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
BIFPGKOA_00319	657322.FPR_05070	6.41e-193	535.0	COG2746@1|root,COG2746@2|Bacteria,1TT5E@1239|Firmicutes,25CER@186801|Clostridia,3WK3S@541000|Ruminococcaceae	186801|Clostridia	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
BIFPGKOA_00320	657322.FPR_05060	7.4e-226	622.0	COG1917@1|root,COG4977@1|root,COG1917@2|Bacteria,COG4977@2|Bacteria,1UK9F@1239|Firmicutes,25FRE@186801|Clostridia,3WSPZ@541000|Ruminococcaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
BIFPGKOA_00322	657322.FPR_05040	2.7e-145	410.0	2C1S2@1|root,2ZJNT@2|Bacteria,1V2MG@1239|Firmicutes,24KZ7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00324	657322.FPR_05020	3.29e-187	520.0	2AYHW@1|root,2ZC56@2|Bacteria,1V2NU@1239|Firmicutes,24FWP@186801|Clostridia,3WRIM@541000|Ruminococcaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
BIFPGKOA_00326	657322.FPR_27610	0.0	899.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3WGEY@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
BIFPGKOA_00327	657322.FPR_27620	1.88e-272	746.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,3WITA@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
BIFPGKOA_00328	657322.FPR_27630	4.51e-206	571.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,3WGY9@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
BIFPGKOA_00329	657322.FPR_27640	5.53e-302	825.0	COG4856@1|root,COG4856@2|Bacteria,1V9AC@1239|Firmicutes,25Q6T@186801|Clostridia,3WHS9@541000|Ruminococcaceae	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
BIFPGKOA_00330	657322.FPR_27650	0.0	1033.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,3WGFA@541000|Ruminococcaceae	186801|Clostridia	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
BIFPGKOA_00331	657322.FPR_27660	4.34e-235	657.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,3WPUP@541000|Ruminococcaceae	186801|Clostridia	S	5-bromo-4-chloroindolyl phosphate hydrolysis protein	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
BIFPGKOA_00332	657322.FPR_27670	0.0	1384.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3WI09@541000|Ruminococcaceae	186801|Clostridia	L	exonuclease	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
BIFPGKOA_00333	657322.FPR_27680	0.0	1512.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,3WGUK@541000|Ruminococcaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
BIFPGKOA_00334	657322.FPR_27690	3.05e-104	301.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3WJM2@541000|Ruminococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
BIFPGKOA_00335	657322.FPR_27700	1.71e-149	420.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,3WHAR@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
BIFPGKOA_00336	657322.FPR_27710	0.0	985.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,3WGA8@541000|Ruminococcaceae	186801|Clostridia	C	Coproporphyrinogen dehydrogenase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
BIFPGKOA_00337	657322.FPR_27720	1.09e-223	616.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia,3WI74@541000|Ruminococcaceae	186801|Clostridia	F	Phosphoribulokinase uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
BIFPGKOA_00338	657322.FPR_27730	7.52e-72	218.0	2ET0Z@1|root,33KJ7@2|Bacteria,1VNW5@1239|Firmicutes,254DV@186801|Clostridia,3WQEJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	zf-ribbon_3
BIFPGKOA_00339	748224.HMPREF9436_00960	1.93e-119	347.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,3WHY1@541000|Ruminococcaceae	186801|Clostridia	S	MazG family	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
BIFPGKOA_00340	657322.FPR_27750	7.71e-52	164.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3WKJ9@541000|Ruminococcaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
BIFPGKOA_00341	657322.FPR_27760	2.34e-47	152.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,3WKNC@541000|Ruminococcaceae	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
BIFPGKOA_00342	428125.CLOLEP_03271	2.86e-09	56.6	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia,3WKKJ@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YabP	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
BIFPGKOA_00343	657322.FPR_27780	1.13e-92	272.0	291HZ@1|root,2ZP4H@2|Bacteria,1W64S@1239|Firmicutes,256EU@186801|Clostridia,3WQKY@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00344	657322.FPR_27790	4.49e-61	188.0	COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,24WD9@186801|Clostridia,3WMHC@541000|Ruminococcaceae	186801|Clostridia	D	septum formation initiator	-	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
BIFPGKOA_00345	657322.FPR_18230	1.7e-107	324.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3WGQS@541000|Ruminococcaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
BIFPGKOA_00346	657322.FPR_18220	4.17e-114	327.0	COG1595@1|root,COG1595@2|Bacteria,1TPJJ@1239|Firmicutes,24JUX@186801|Clostridia,3WRU9@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BIFPGKOA_00347	657322.FPR_18210	1.24e-152	429.0	COG5660@1|root,COG5660@2|Bacteria,1VKXY@1239|Firmicutes,24UK9@186801|Clostridia,3WMGN@541000|Ruminococcaceae	186801|Clostridia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
BIFPGKOA_00351	657322.FPR_18170	3.26e-310	845.0	COG0739@1|root,COG0739@2|Bacteria,1V7QV@1239|Firmicutes,24M4A@186801|Clostridia,3WNIT@541000|Ruminococcaceae	186801|Clostridia	M	Peptidase, M23 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
BIFPGKOA_00352	657322.FPR_18160	1.11e-28	103.0	28ZEN@1|root,2ZM68@2|Bacteria,1W2T3@1239|Firmicutes,257D2@186801|Clostridia,3WRA6@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00353	748224.HMPREF9436_02018	4.72e-211	587.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,3WH2W@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
BIFPGKOA_00354	657322.FPR_18140	0.0	927.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,3WGDY@541000|Ruminococcaceae	186801|Clostridia	J	asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
BIFPGKOA_00355	657322.FPR_18130	9.12e-119	341.0	2BCB7@1|root,325WH@2|Bacteria,1VU5S@1239|Firmicutes	657322.FPR_18130|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00356	657322.FPR_18120	6.9e-243	670.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,3WGV1@541000|Ruminococcaceae	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
BIFPGKOA_00357	657322.FPR_18110	4.59e-175	489.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,3WGVA@541000|Ruminococcaceae	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
BIFPGKOA_00358	748224.HMPREF9436_02023	4.57e-45	146.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3WKKU@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
BIFPGKOA_00360	657322.FPR_18080	3.41e-73	220.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,3WK2T@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
BIFPGKOA_00361	657322.FPR_18070	1.01e-228	631.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,25EAS@186801|Clostridia,3WGIZ@541000|Ruminococcaceae	186801|Clostridia	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
BIFPGKOA_00362	657322.FPR_18060	1.36e-96	281.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,3WJNA@541000|Ruminococcaceae	186801|Clostridia	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
BIFPGKOA_00363	657322.FPR_18050	4.62e-185	515.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,24E6R@186801|Clostridia,3WIZM@541000|Ruminococcaceae	186801|Clostridia	M	Serine-type D-Ala-D-Ala carboxypeptidase	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Big_2,VanY
BIFPGKOA_00364	657322.FPR_18040	1.21e-84	254.0	2C9HT@1|root,2ZDJ9@2|Bacteria,1W4SA@1239|Firmicutes,255IW@186801|Clostridia,3WQUU@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4358)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4358
BIFPGKOA_00365	748224.HMPREF9436_02030	0.0	899.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH3T@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
BIFPGKOA_00366	657322.FPR_18020	4.91e-285	778.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,3WINY@541000|Ruminococcaceae	186801|Clostridia	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
BIFPGKOA_00367	657322.FPR_19970	0.0	1106.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,24BJV@186801|Clostridia,3WHII@541000|Ruminococcaceae	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
BIFPGKOA_00368	657322.FPR_19980	6.35e-176	490.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3WGVE@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BIFPGKOA_00369	657322.FPR_19990	1.27e-273	750.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3WGNK@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	macB1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
BIFPGKOA_00370	657322.FPR_20000	0.0	1297.0	COG0737@1|root,COG0737@2|Bacteria,1UK63@1239|Firmicutes,25FMA@186801|Clostridia	186801|Clostridia	F	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
BIFPGKOA_00371	657322.FPR_20010	4.49e-188	522.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,3WKFF@541000|Ruminococcaceae	186801|Clostridia	S	Phosphoribosyl transferase domain	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
BIFPGKOA_00373	748224.HMPREF9436_01074	2.25e-20	88.2	COG4974@1|root,COG4974@2|Bacteria,1UK9E@1239|Firmicutes,25FRD@186801|Clostridia	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
BIFPGKOA_00374	471875.RUMLAC_01470	2.98e-08	61.6	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,3WIN0@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_2,Pkinase,TPR_16,TPR_8
BIFPGKOA_00376	657322.FPR_20070	0.0	926.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH3T@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
BIFPGKOA_00377	1280685.AUKC01000025_gene1064	5.98e-28	121.0	COG0457@1|root,COG0457@2|Bacteria,1V0II@1239|Firmicutes,24C9M@186801|Clostridia,4C0C1@830|Butyrivibrio	186801|Clostridia	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX,DHHW
BIFPGKOA_00378	657322.FPR_20090	3.37e-70	218.0	28QE7@1|root,2ZCWI@2|Bacteria,1W2JK@1239|Firmicutes,24QIX@186801|Clostridia	186801|Clostridia	S	No similarity found	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00380	657322.FPR_20110	2.28e-292	797.0	COG2173@1|root,COG3807@1|root,COG2173@2|Bacteria,COG3807@2|Bacteria,1VMR7@1239|Firmicutes	1239|Firmicutes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15,SH3_3,SH3_4,VanY
BIFPGKOA_00382	657322.FPR_20120	5.08e-282	773.0	COG2379@1|root,COG2379@2|Bacteria,1TSQH@1239|Firmicutes,249XX@186801|Clostridia,3WGPY@541000|Ruminococcaceae	186801|Clostridia	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
BIFPGKOA_00384	657322.FPR_29030	3.79e-116	332.0	COG2954@1|root,COG2954@2|Bacteria,1VJMJ@1239|Firmicutes,257RA@186801|Clostridia,3WJIX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00385	748224.HMPREF9436_01440	1.27e-119	344.0	COG0705@1|root,COG0705@2|Bacteria,1V1C3@1239|Firmicutes,24GPR@186801|Clostridia,3WJQT@541000|Ruminococcaceae	186801|Clostridia	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid
BIFPGKOA_00386	657322.FPR_29050	6.34e-137	386.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia,3WJ2S@541000|Ruminococcaceae	186801|Clostridia	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
BIFPGKOA_00387	657322.FPR_29060	7.36e-149	420.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,24B9Z@186801|Clostridia,3WHQ9@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
BIFPGKOA_00388	657322.FPR_29070	0.0	944.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,248XW@186801|Clostridia,3WHB7@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15780	AAA_26,CbiA,GATase_3
BIFPGKOA_00389	657322.FPR_29080	2.2e-231	639.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,3WHN4@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
BIFPGKOA_00390	657322.FPR_29090	1.48e-219	606.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia,3WGT1@541000|Ruminococcaceae	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
BIFPGKOA_00391	657322.FPR_29100	1.31e-141	399.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3WJCY@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
BIFPGKOA_00392	657322.FPR_29110	4.33e-69	209.0	COG2087@1|root,COG2087@2|Bacteria,1UQZG@1239|Firmicutes,258SR@186801|Clostridia,3WMDV@541000|Ruminococcaceae	186801|Clostridia	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	-	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
BIFPGKOA_00393	657322.FPR_29120	1.38e-175	489.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,3WIUR@541000|Ruminococcaceae	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
BIFPGKOA_00394	657322.FPR_29130	2.41e-113	326.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,3WK4Z@541000|Ruminococcaceae	186801|Clostridia	H	adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
BIFPGKOA_00395	657322.FPR_29140	1.76e-237	655.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,3WGSW@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
BIFPGKOA_00396	657322.FPR_29150	1.3e-315	860.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,3WH17@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
BIFPGKOA_00397	657322.FPR_29160	6.5e-269	738.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,3WGQY@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
BIFPGKOA_00398	657322.FPR_29170	1.88e-166	466.0	COG2099@1|root,COG2099@2|Bacteria,1UHWY@1239|Firmicutes,24GIQ@186801|Clostridia,3WJ9U@541000|Ruminococcaceae	186801|Clostridia	H	reductase	cobK	-	1.3.1.106,1.3.1.54,1.3.1.76,4.99.1.4	ko:K02304,ko:K05895	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947,R05150,R05812	RC01012,RC01034,RC01280	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiJ,NAD_binding_7
BIFPGKOA_00399	657322.FPR_29180	6.08e-177	493.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,3WHE5@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-3B	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
BIFPGKOA_00400	657322.FPR_29190	6.06e-227	626.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,3WHCR@541000|Ruminococcaceae	186801|Clostridia	H	Cobalamin synthesis G C-terminus	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
BIFPGKOA_00401	657322.FPR_29200	5.63e-176	491.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia,3WH3H@541000|Ruminococcaceae	186801|Clostridia	H	precorrin-4 C11-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
BIFPGKOA_00402	657322.FPR_29210	7.36e-203	576.0	COG1120@1|root,COG1903@1|root,COG1120@2|Bacteria,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,3WH1E@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
BIFPGKOA_00403	657322.FPR_28000	3.32e-193	536.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3WGHP@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
BIFPGKOA_00404	657322.FPR_27990	5.57e-220	607.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3WGWB@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferase family 4	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
BIFPGKOA_00405	657322.FPR_27980	0.0	890.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3WIF4@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_00406	657322.FPR_27970	9.13e-133	377.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,3WI1Y@541000|Ruminococcaceae	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
BIFPGKOA_00407	657322.FPR_27960	8.12e-242	666.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,3WJT0@541000|Ruminococcaceae	186801|Clostridia	M	mechanosensitive ion channel	-	-	-	ko:K16052,ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3,1.A.23.4	-	-	MS_channel
BIFPGKOA_00408	657322.FPR_27950	3.05e-261	717.0	COG0738@1|root,COG0738@2|Bacteria,1TPB5@1239|Firmicutes,24913@186801|Clostridia,3WHGF@541000|Ruminococcaceae	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BIFPGKOA_00409	657322.FPR_27940	0.0	1397.0	COG1680@1|root,COG1680@2|Bacteria,1UC2C@1239|Firmicutes,24B3Q@186801|Clostridia,3WJ3P@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase class C	-	-	3.4.16.4	ko:K21469	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase
BIFPGKOA_00410	657322.FPR_27930	1.25e-85	252.0	arCOG12631@1|root,3172B@2|Bacteria,1V77G@1239|Firmicutes,24KJW@186801|Clostridia,3WKZS@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_1
BIFPGKOA_00413	748224.HMPREF9436_02986	0.0	963.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,3WHA0@541000|Ruminococcaceae	186801|Clostridia	J	Metallo-beta-lactamase domain protein	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
BIFPGKOA_00414	657322.FPR_27910	0.0	1200.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3WGEU@541000|Ruminococcaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
BIFPGKOA_00416	657322.FPR_27890	0.0	1474.0	COG2274@1|root,COG3271@1|root,COG2274@2|Bacteria,COG3271@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia,3WI0H@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type bacteriocin transporter	-	-	-	ko:K20344	ko02010,ko02024,map02010,map02024	-	-	-	ko00000,ko00001,ko02000	3.A.1.112	-	-	ABC_membrane,ABC_tran,Peptidase_C39
BIFPGKOA_00417	657322.FPR_31730	1.89e-73	220.0	COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,24MZ2@186801|Clostridia,3WM2A@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
BIFPGKOA_00419	657322.FPR_31710	2.29e-194	540.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,24AQE@186801|Clostridia,3WGMZ@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
BIFPGKOA_00420	657322.FPR_31700	1.63e-174	486.0	COG0727@1|root,COG0727@2|Bacteria,1V0FA@1239|Firmicutes,24CDU@186801|Clostridia,3WKMK@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
BIFPGKOA_00421	657322.FPR_31690	3.72e-208	580.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3WHHG@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
BIFPGKOA_00422	748224.HMPREF9436_00652	2.22e-192	537.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3WGJI@541000|Ruminococcaceae	186801|Clostridia	S	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
BIFPGKOA_00423	657322.FPR_31670	2.37e-179	500.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3WHK4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
BIFPGKOA_00424	657322.FPR_31660	1.04e-274	749.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WI8G@541000|Ruminococcaceae	186801|Clostridia	H	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
BIFPGKOA_00425	657322.FPR_31650	1.33e-225	620.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia,3WHUE@541000|Ruminococcaceae	186801|Clostridia	C	pyruvate formate lyase activating	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
BIFPGKOA_00426	657322.FPR_31640	0.0	1363.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,3WGTB@541000|Ruminococcaceae	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
BIFPGKOA_00427	411483.FAEPRAA2165_03439	4.77e-289	793.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3WGXG@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
BIFPGKOA_00428	657322.FPR_31620	2.82e-190	528.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,3WIBU@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
BIFPGKOA_00429	657322.FPR_31610	2.87e-222	614.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,3WJBS@541000|Ruminococcaceae	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
BIFPGKOA_00430	657322.FPR_31600	1.47e-213	590.0	COG3935@1|root,COG3935@2|Bacteria	2|Bacteria	-	-	dnaD	-	-	ko:K02086	-	-	-	-	ko00000	-	-	-	DnaB_2,HTH_36
BIFPGKOA_00431	657322.FPR_31590	6.48e-91	265.0	2E3XF@1|root,30TZG@2|Bacteria,1US5V@1239|Firmicutes,25A4N@186801|Clostridia,3WR61@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00433	657322.FPR_31570	8.09e-33	117.0	COG2261@1|root,COG2261@2|Bacteria,1VKCP@1239|Firmicutes,24U0Q@186801|Clostridia,3WR89@541000|Ruminococcaceae	186801|Clostridia	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
BIFPGKOA_00434	657322.FPR_31560	4.52e-88	262.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3WGWR@541000|Ruminococcaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
BIFPGKOA_00435	657322.FPR_23870	0.0	960.0	COG0768@1|root,COG0768@2|Bacteria,1TQKI@1239|Firmicutes,25CAC@186801|Clostridia,3WI5D@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
BIFPGKOA_00436	657322.FPR_23880	1.83e-45	147.0	COG1314@1|root,COG1314@2|Bacteria,1VP2Z@1239|Firmicutes,24UWV@186801|Clostridia	186801|Clostridia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
BIFPGKOA_00437	748224.HMPREF9436_00140	0.0	1321.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3WGHJ@541000|Ruminococcaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
BIFPGKOA_00438	699218.HMPREF0889_1470	3.43e-17	80.5	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4H41Y@909932|Negativicutes	909932|Negativicutes	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
BIFPGKOA_00439	657322.FPR_23920	1.16e-120	345.0	COG1309@1|root,COG1309@2|Bacteria,1V7SY@1239|Firmicutes,24JI6@186801|Clostridia,3WQFN@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BIFPGKOA_00440	657322.FPR_23930	0.0	1612.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,3WRX8@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	lacZ	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
BIFPGKOA_00441	411483.FAEPRAA2165_02255	9.78e-312	852.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia,3WKCH@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
BIFPGKOA_00442	411483.FAEPRAA2165_02256	0.0	1004.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,24NSC@186801|Clostridia,3WIB3@541000|Ruminococcaceae	186801|Clostridia	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
BIFPGKOA_00443	657322.FPR_13150	7.9e-272	754.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,3WGW2@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
BIFPGKOA_00444	411468.CLOSCI_02784	1.47e-30	108.0	COG2944@1|root,COG2944@2|Bacteria,1VIYC@1239|Firmicutes,24RHE@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
BIFPGKOA_00445	1232453.BAIF02000016_gene3115	3.98e-111	327.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,26A68@186813|unclassified Clostridiales	186801|Clostridia	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
BIFPGKOA_00446	1235802.C823_05187	9.1e-08	59.7	COG3935@1|root,COG3935@2|Bacteria,1TQ65@1239|Firmicutes,249Q8@186801|Clostridia,25WSR@186806|Eubacteriaceae	186801|Clostridia	L	N-terminal phage replisome organiser (Phage_rep_org_N)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_rep_org_N
BIFPGKOA_00447	411483.FAEPRAA2165_02535	1.45e-67	222.0	COG1475@1|root,COG1475@2|Bacteria,1V2SD@1239|Firmicutes,24GNZ@186801|Clostridia,3WJEB@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00448	877414.ATWA01000018_gene2072	0.0	1506.0	COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,248A6@186801|Clostridia,26807@186813|unclassified Clostridiales	186801|Clostridia	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
BIFPGKOA_00450	1226325.HMPREF1548_02139	1.63e-15	85.1	COG4127@1|root,COG4127@2|Bacteria,1VAIE@1239|Firmicutes,24TBJ@186801|Clostridia,36MAH@31979|Clostridiaceae	186801|Clostridia	S	FRG	-	-	-	-	-	-	-	-	-	-	-	-	FRG
BIFPGKOA_00451	477228.YO5_14436	8.35e-73	242.0	COG0732@1|root,COG0732@2|Bacteria,1Q4FB@1224|Proteobacteria,1RS7D@1236|Gammaproteobacteria,1Z3CQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	V	COG0732 Restriction endonuclease S subunits	hsdS	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
BIFPGKOA_00452	411483.FAEPRAA2165_03333	1.13e-115	343.0	arCOG14015@1|root,30H02@2|Bacteria,1VA7Y@1239|Firmicutes,24N2U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00453	411483.FAEPRAA2165_03332	0.0	1179.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,3WGXV@541000|Ruminococcaceae	186801|Clostridia	L	N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
BIFPGKOA_00454	657322.FPR_24130	0.0	901.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WGD4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
BIFPGKOA_00455	657322.FPR_24140	3.63e-214	590.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ0Q@1239|Firmicutes,24YIV@186801|Clostridia,3WIE7@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
BIFPGKOA_00456	657322.FPR_24150	1.08e-306	836.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3WHNU@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
BIFPGKOA_00459	657322.FPR_24180	0.0	994.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3WGN6@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
BIFPGKOA_00460	411483.FAEPRAA2165_01981	2.63e-11	62.4	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,3WHYW@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
BIFPGKOA_00461	657322.FPR_06410	8.73e-72	220.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia,3WIUE@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type metal ion transport system permease component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
BIFPGKOA_00462	657322.FPR_06420	4.02e-315	857.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WH4H@541000|Ruminococcaceae	186801|Clostridia	E	O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
BIFPGKOA_00463	657322.FPR_06430	2.71e-233	640.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3WGY0@541000|Ruminococcaceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	AA_kinase,HTS
BIFPGKOA_00464	657322.FPR_06440	4.07e-213	588.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,3WHUR@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
BIFPGKOA_00465	657322.FPR_06450	7.29e-126	357.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,3WIDH@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
BIFPGKOA_00466	748224.HMPREF9436_02320	2.14e-161	459.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,24ABV@186801|Clostridia,3WGAX@541000|Ruminococcaceae	186801|Clostridia	H	Pyridoxal kinase	-	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
BIFPGKOA_00469	657322.FPR_06490	0.0	978.0	COG1145@1|root,COG2221@1|root,COG4624@1|root,COG1145@2|Bacteria,COG2221@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,3WGZI@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
BIFPGKOA_00470	657322.FPR_06500	2.41e-315	858.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,3WG80@541000|Ruminococcaceae	186801|Clostridia	J	tRNA methylthiotransferase YqeV	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
BIFPGKOA_00472	657322.FPR_06510	8.53e-287	784.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,3WHE1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
BIFPGKOA_00473	657322.FPR_06520	0.0	882.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WHJX@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
BIFPGKOA_00474	748224.HMPREF9436_02306	5.13e-87	256.0	COG0433@1|root,COG0433@2|Bacteria,1VF8X@1239|Firmicutes,24N9T@186801|Clostridia,3WJSW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00475	657322.FPR_06540	8.53e-120	342.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,3WJHK@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
BIFPGKOA_00476	411483.FAEPRAA2165_01715	8.45e-38	126.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3WKID@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
BIFPGKOA_00477	657322.FPR_06560	0.0	899.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,3WGI9@541000|Ruminococcaceae	186801|Clostridia	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
BIFPGKOA_00478	657322.FPR_12990	4.54e-301	822.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3WGH0@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
BIFPGKOA_00479	657322.FPR_13020	1.6e-218	603.0	COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,24A7U@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
BIFPGKOA_00480	657322.FPR_13030	1.76e-268	740.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WHD5@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
BIFPGKOA_00481	657322.FPR_01310	1.37e-234	649.0	COG2199@1|root,COG2199@2|Bacteria,1TSU4@1239|Firmicutes,24DMY@186801|Clostridia,3WPF4@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
BIFPGKOA_00482	748224.HMPREF9436_02262	2.57e-49	164.0	2ES3K@1|root,33JNI@2|Bacteria,1VKAS@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00483	657322.FPR_01330	3.77e-108	313.0	COG0671@1|root,COG0671@2|Bacteria,1V7XD@1239|Firmicutes,25BF5@186801|Clostridia,3WS6D@541000|Ruminococcaceae	186801|Clostridia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
BIFPGKOA_00484	657322.FPR_01340	6.59e-229	631.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3WGC8@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	scrK	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
BIFPGKOA_00485	657322.FPR_01350	2.22e-296	810.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia,3WH7U@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_00486	748224.HMPREF9436_01798	2.52e-166	469.0	COG2207@1|root,COG2207@2|Bacteria,1VEKW@1239|Firmicutes,24SZV@186801|Clostridia,3WM13@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
BIFPGKOA_00487	748224.HMPREF9436_01797	1.08e-267	733.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGC7@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
BIFPGKOA_00488	748224.HMPREF9436_01796	2.74e-211	584.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,249AX@186801|Clostridia,3WJR3@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BIFPGKOA_00489	748224.HMPREF9436_01795	1.11e-172	481.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia,3WH52@541000|Ruminococcaceae	186801|Clostridia	S	Methyltransferase, YaeB family	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
BIFPGKOA_00490	877420.ATVW01000009_gene677	4.11e-15	70.1	2EGIZ@1|root,33AB6@2|Bacteria,1VKU9@1239|Firmicutes,25HRZ@186801|Clostridia,27UP2@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00491	748224.HMPREF9436_01793	7.84e-146	410.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3WM48@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_3,HTH_31,Peptidase_S24
BIFPGKOA_00495	748224.HMPREF9436_01136	1.16e-47	153.0	2CZEX@1|root,32SNV@2|Bacteria,1VEBP@1239|Firmicutes,24Q7Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00497	748224.HMPREF9436_01143	1.77e-50	160.0	2CZEX@1|root,32SNV@2|Bacteria,1VEBP@1239|Firmicutes,24Q7Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00498	718252.FP2_28560	4.64e-197	548.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia,3WGRZ@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
BIFPGKOA_00499	657322.FPR_17450	7.17e-204	565.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,247KZ@186801|Clostridia,3WNP8@541000|Ruminococcaceae	186801|Clostridia	H	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
BIFPGKOA_00500	718252.FP2_28580	0.0	910.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,3WG8J@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	2.7.1.211	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
BIFPGKOA_00501	718252.FP2_28590	2.56e-248	682.0	COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,248R7@186801|Clostridia,3WQXH@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF871)	-	-	-	ko:K09963	-	-	-	-	ko00000	-	-	-	DUF871
BIFPGKOA_00502	657322.FPR_17480	1.98e-312	853.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_00503	657322.FPR_17490	5.75e-205	566.0	COG1387@1|root,COG1387@2|Bacteria,1V2QZ@1239|Firmicutes,24GV5@186801|Clostridia,3WJ8J@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
BIFPGKOA_00504	657322.FPR_17500	1.57e-148	418.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,3WJ30@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
BIFPGKOA_00505	657322.FPR_17510	1.14e-179	500.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,3WGQE@541000|Ruminococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
BIFPGKOA_00506	657322.FPR_17520	2.29e-164	460.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,24GBJ@186801|Clostridia,3WH1N@541000|Ruminococcaceae	186801|Clostridia	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
BIFPGKOA_00507	657322.FPR_17530	6.7e-141	398.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,3WGIA@541000|Ruminococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
BIFPGKOA_00508	657322.FPR_17540	9.24e-146	410.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,3WH5P@541000|Ruminococcaceae	186801|Clostridia	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
BIFPGKOA_00509	657322.FPR_17550	2.57e-250	687.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,3WGEN@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
BIFPGKOA_00510	657322.FPR_17560	2.96e-178	504.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,3WGCJ@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
BIFPGKOA_00511	657322.FPR_30880	3.23e-153	432.0	COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,3WIDD@541000|Ruminococcaceae	186801|Clostridia	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
BIFPGKOA_00512	657322.FPR_30870	3.04e-59	183.0	2CCD5@1|root,32RVD@2|Bacteria,1UPQI@1239|Firmicutes,25HM0@186801|Clostridia,3WREV@541000|Ruminococcaceae	186801|Clostridia	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
BIFPGKOA_00513	657322.FPR_30860	1.29e-194	540.0	COG1091@1|root,COG1091@2|Bacteria,1TQSX@1239|Firmicutes,24G9Q@186801|Clostridia,3WN5F@541000|Ruminococcaceae	186801|Clostridia	M	RmlD substrate binding domain	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
BIFPGKOA_00514	748224.HMPREF9436_01593	2.94e-302	828.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3WGM2@541000|Ruminococcaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pbuX	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
BIFPGKOA_00515	657322.FPR_30830	2.22e-152	428.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24KIZ@186801|Clostridia,3WKNV@541000|Ruminococcaceae	186801|Clostridia	S	MobA-like NTP transferase domain	ygfJ	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
BIFPGKOA_00516	657322.FPR_30820	1.43e-181	506.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia,3WIEX@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain in molybdopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
BIFPGKOA_00517	657322.FPR_30810	2.22e-112	322.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia,3WJ5N@541000|Ruminococcaceae	186801|Clostridia	C	[2Fe-2S] binding domain	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
BIFPGKOA_00518	748224.HMPREF9436_01589	0.0	1431.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WHIV@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
BIFPGKOA_00519	657322.FPR_30790	2.79e-162	454.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,3WKRV@541000|Ruminococcaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00520	657322.FPR_30780	4.73e-242	665.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,3WI1B@541000|Ruminococcaceae	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
BIFPGKOA_00521	657322.FPR_30770	1.45e-136	387.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,3WJCH@541000|Ruminococcaceae	186801|Clostridia	O	DsrE/DsrF-like family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
BIFPGKOA_00522	748224.HMPREF9436_01585	4.99e-209	585.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,3WH06@541000|Ruminococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
BIFPGKOA_00523	657322.FPR_30750	2.5e-51	161.0	2DR4V@1|root,33A63@2|Bacteria,1VKGM@1239|Firmicutes,24UDH@186801|Clostridia,3WMI7@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
BIFPGKOA_00524	657322.FPR_30740	3.07e-241	664.0	COG1975@1|root,COG1975@2|Bacteria,1UZDB@1239|Firmicutes,25D6N@186801|Clostridia,3WJ0T@541000|Ruminococcaceae	186801|Clostridia	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
BIFPGKOA_00526	657322.FPR_01960	0.0	1595.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3WGRB@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the FtsK SpoIIIE SftA family	spoIIIE	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
BIFPGKOA_00527	657322.FPR_01970	5.89e-161	451.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,3WGED@541000|Ruminococcaceae	186801|Clostridia	OU	Psort location Cytoplasmic, score	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
BIFPGKOA_00528	657322.FPR_01980	4.69e-151	424.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,3WHYJ@541000|Ruminococcaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
BIFPGKOA_00529	657322.FPR_01990	1.36e-144	407.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,24CVH@186801|Clostridia,3WNBN@541000|Ruminococcaceae	186801|Clostridia	F	thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
BIFPGKOA_00530	657322.FPR_02000	0.0	894.0	COG1653@1|root,COG1653@2|Bacteria,1TR4M@1239|Firmicutes,24BFM@186801|Clostridia,3WJ7Y@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K10192	ko02010,map02010	M00202,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.11	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
BIFPGKOA_00531	657322.FPR_02010	1.55e-222	613.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,248DR@186801|Clostridia,3WISE@541000|Ruminococcaceae	186801|Clostridia	P	carbohydrate ABC transporter membrane protein 1 CUT1 family	-	-	-	ko:K02025,ko:K10193	ko02010,map02010	M00202,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.11	-	-	BPD_transp_1
BIFPGKOA_00532	657322.FPR_02020	4.01e-210	580.0	COG0395@1|root,COG0395@2|Bacteria,1TSYB@1239|Firmicutes,24AKM@186801|Clostridia,3WIYF@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10194	ko02010,map02010	M00202	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.11	-	-	BPD_transp_1
BIFPGKOA_00533	657322.FPR_02030	3.98e-173	485.0	COG2169@1|root,COG2169@2|Bacteria,1UK9J@1239|Firmicutes,25BJT@186801|Clostridia,3WKTP@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
BIFPGKOA_00534	657322.FPR_02040	0.0	1054.0	COG5434@1|root,COG5434@2|Bacteria,1TQQW@1239|Firmicutes,24A0R@186801|Clostridia,3WI0S@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
BIFPGKOA_00535	657322.FPR_02050	1.48e-295	804.0	COG4225@1|root,COG4225@2|Bacteria,1TRJ7@1239|Firmicutes,24806@186801|Clostridia,3WH3B@541000|Ruminococcaceae	186801|Clostridia	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
BIFPGKOA_00536	657322.FPR_03370	8.81e-302	826.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,3WG82@541000|Ruminococcaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
BIFPGKOA_00537	411483.FAEPRAA2165_00432	1.38e-285	784.0	COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia,3WHZ5@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
BIFPGKOA_00538	657322.FPR_03350	2.89e-163	457.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24DB9@186801|Clostridia,3WHMG@541000|Ruminococcaceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
BIFPGKOA_00539	411483.FAEPRAA2165_00435	4.18e-77	231.0	COG3279@1|root,COG3279@2|Bacteria,1VAGQ@1239|Firmicutes,24Q19@186801|Clostridia,3WMHQ@541000|Ruminococcaceae	186801|Clostridia	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
BIFPGKOA_00540	657322.FPR_03330	0.0	1336.0	COG4257@1|root,COG4257@2|Bacteria,1UKZR@1239|Firmicutes,25G84@186801|Clostridia,3WHVB@541000|Ruminococcaceae	186801|Clostridia	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00541	748224.HMPREF9436_01904	0.0	924.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia,3WHUB@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
BIFPGKOA_00542	411471.SUBVAR_04817	2.11e-71	227.0	COG2407@1|root,COG2407@2|Bacteria,1UDWP@1239|Firmicutes,24ARY@186801|Clostridia,3WPMJ@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of L-arabinose to L-ribulose	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_Isome
BIFPGKOA_00543	657322.FPR_25510	7.88e-208	573.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia,3WNW2@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
BIFPGKOA_00544	1410612.JNKO01000010_gene439	3.91e-57	178.0	COG3254@1|root,COG3254@2|Bacteria,1VA1C@1239|Firmicutes,24JG9@186801|Clostridia	186801|Clostridia	G	Involved in the anomeric conversion of L-rhamnose	rhaM	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
BIFPGKOA_00545	411470.RUMGNA_01003	1.47e-22	97.4	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3XZAD@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DctM
BIFPGKOA_00546	411470.RUMGNA_01004	5.5e-89	275.0	COG2169@1|root,COG2169@2|Bacteria,1UUUH@1239|Firmicutes,25KCH@186801|Clostridia,3Y21B@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
BIFPGKOA_00547	411470.RUMGNA_01005	5.72e-234	648.0	COG4225@1|root,COG4225@2|Bacteria,1UUV4@1239|Firmicutes,25NGR@186801|Clostridia,3Y22W@572511|Blautia	186801|Clostridia	S	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
BIFPGKOA_00548	718252.FP2_13930	5.49e-49	156.0	2CZEX@1|root,32SNV@2|Bacteria,1VEBP@1239|Firmicutes,24Q7Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00549	748224.HMPREF9436_02683	0.0	1006.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3WHUY@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
BIFPGKOA_00550	397290.C810_02908	3.76e-294	815.0	COG1653@1|root,COG1653@2|Bacteria,1TS6D@1239|Firmicutes,248CI@186801|Clostridia,27JZY@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1
BIFPGKOA_00551	397290.C810_02909	7.37e-163	462.0	COG0395@1|root,COG0395@2|Bacteria,1TQ9F@1239|Firmicutes,24846@186801|Clostridia,27KJ7@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
BIFPGKOA_00552	552398.HMPREF0866_00159	6.58e-169	478.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,248XU@186801|Clostridia,3WHDQ@541000|Ruminococcaceae	186801|Clostridia	P	carbohydrate ABC transporter membrane protein 1 CUT1 family	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
BIFPGKOA_00553	1235792.C808_03985	1.25e-143	416.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,27JY6@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
BIFPGKOA_00554	552398.HMPREF0866_00157	1.4e-46	161.0	2DJT4@1|root,32UDS@2|Bacteria,1VDA1@1239|Firmicutes,24SD3@186801|Clostridia,3WK3G@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00555	1235792.C808_03987	8.83e-43	149.0	2FFQ3@1|root,347ME@2|Bacteria,1W137@1239|Firmicutes,252VZ@186801|Clostridia,27S9G@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00556	552398.HMPREF0866_00155	6.43e-57	189.0	2E8K9@1|root,332XY@2|Bacteria,1VDJS@1239|Firmicutes,24PSM@186801|Clostridia,3WST6@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00557	718252.FP2_08640	1.35e-212	588.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3WGC8@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
BIFPGKOA_00558	411483.FAEPRAA2165_02769	0.0	1255.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WH4U@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain	ams	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
BIFPGKOA_00559	657322.FPR_07500	3.42e-313	855.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WH3J@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
BIFPGKOA_00560	657322.FPR_07510	1.71e-209	579.0	COG0583@1|root,COG0583@2|Bacteria,1TP9T@1239|Firmicutes,24AYF@186801|Clostridia,3WJHN@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BIFPGKOA_00561	657322.FPR_07520	8.73e-234	643.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24BWQ@186801|Clostridia,3WK7V@541000|Ruminococcaceae	186801|Clostridia	G	TRAP transporter solute receptor, DctP family	-	-	-	-	-	-	-	-	-	-	-	-	DctP
BIFPGKOA_00562	411483.FAEPRAA2165_01191	1.9e-281	773.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3WI33@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM
BIFPGKOA_00563	748224.HMPREF9436_00720	3.23e-121	347.0	COG3090@1|root,COG3090@2|Bacteria,1V3SM@1239|Firmicutes,24AP0@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
BIFPGKOA_00564	411483.FAEPRAA2165_01193	1.04e-246	677.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24BWQ@186801|Clostridia,3WK7V@541000|Ruminococcaceae	186801|Clostridia	G	TRAP transporter solute receptor, DctP family	-	-	-	-	-	-	-	-	-	-	-	-	DctP
BIFPGKOA_00565	748224.HMPREF9436_00723	2.03e-179	500.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24BBP@186801|Clostridia,3WJP7@541000|Ruminococcaceae	186801|Clostridia	K	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
BIFPGKOA_00566	657322.FPR_07570	0.0	908.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia,3WHGB@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
BIFPGKOA_00567	657322.FPR_07580	5.45e-154	432.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WIW5@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
BIFPGKOA_00568	411483.FAEPRAA2165_01198	3.21e-155	437.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,3WGU7@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
BIFPGKOA_00569	657322.FPR_25710	4.05e-214	592.0	COG0524@1|root,COG0524@2|Bacteria,1TQR4@1239|Firmicutes,24AUP@186801|Clostridia,3WMTE@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	-	-	2.7.1.15,2.7.1.83	ko:K00852,ko:K16328	ko00030,ko00240,map00030,map00240	-	R01051,R02750,R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HTH_24,PfkB
BIFPGKOA_00570	657322.FPR_25720	4.78e-221	610.0	COG0469@1|root,COG0469@2|Bacteria,1TQC0@1239|Firmicutes,24CHE@186801|Clostridia,3WMZU@541000|Ruminococcaceae	186801|Clostridia	H	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
BIFPGKOA_00571	657322.FPR_25730	6.36e-131	371.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,3WIK0@541000|Ruminococcaceae	186801|Clostridia	S	Phosphoesterase	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
BIFPGKOA_00572	657322.FPR_25740	1.35e-298	817.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3WGJC@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_00573	657322.FPR_25750	0.0	876.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3WH5C@541000|Ruminococcaceae	186801|Clostridia	E	amino acid carrier protein	agcS_2	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
BIFPGKOA_00574	411483.FAEPRAA2165_01831	1.71e-267	736.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,24AR8@186801|Clostridia,3WH3M@541000|Ruminococcaceae	186801|Clostridia	E	Thermophilic metalloprotease (M29)	pepS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
BIFPGKOA_00575	657322.FPR_25770	5.61e-113	324.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,3WJSY@541000|Ruminococcaceae	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
BIFPGKOA_00576	657322.FPR_25780	1.19e-258	709.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3WG8A@541000|Ruminococcaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
BIFPGKOA_00577	657322.FPR_25790	3.45e-64	196.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,3WJZN@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
BIFPGKOA_00578	657322.FPR_25800	5.95e-84	248.0	COG1358@1|root,COG1358@2|Bacteria,1VMU4@1239|Firmicutes,24V54@186801|Clostridia	186801|Clostridia	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
BIFPGKOA_00579	657322.FPR_25810	0.0	1444.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,3WHTD@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
BIFPGKOA_00580	657322.FPR_13740	3.9e-168	476.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
BIFPGKOA_00581	411483.FAEPRAA2165_02496	1.42e-70	211.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
BIFPGKOA_00582	657322.FPR_13760	1.67e-248	681.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes	1239|Firmicutes	M	Glycosyltransferase group 2 family protein	-	-	-	ko:K19427	-	-	-	-	ko00000,ko01000	-	GT2	-	Glycos_transf_2
BIFPGKOA_00583	657322.FPR_13770	0.0	895.0	2EIXX@1|root,338RG@2|Bacteria,1VJYN@1239|Firmicutes,25DS0@186801|Clostridia	186801|Clostridia	S	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
BIFPGKOA_00584	357276.EL88_06595	8.19e-80	256.0	COG0438@1|root,COG0438@2|Bacteria,4NK0S@976|Bacteroidetes,2FPH2@200643|Bacteroidia,4ARF4@815|Bacteroidaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
BIFPGKOA_00585	657322.FPR_13790	1.01e-293	801.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
BIFPGKOA_00586	657322.FPR_13800	0.0	1165.0	COG3206@1|root,COG3206@2|Bacteria,1V867@1239|Firmicutes,24G2T@186801|Clostridia,3WRY8@541000|Ruminococcaceae	186801|Clostridia	M	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
BIFPGKOA_00587	657322.FPR_13810	9.98e-288	788.0	2EXX1@1|root,33R64@2|Bacteria,1VTQG@1239|Firmicutes,24Q1J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00588	657322.FPR_13820	6.88e-231	636.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,3WJTI@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
BIFPGKOA_00589	657322.FPR_13830	0.0	1010.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WGRU@541000|Ruminococcaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
BIFPGKOA_00590	657322.FPR_28910	3.8e-73	227.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,3WGIY@541000|Ruminococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
BIFPGKOA_00591	657322.FPR_28920	8.34e-132	375.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,3WK2C@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
BIFPGKOA_00592	748224.HMPREF9436_01249	7.45e-97	288.0	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,24JB5@186801|Clostridia,3WKAS@541000|Ruminococcaceae	186801|Clostridia	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
BIFPGKOA_00593	657322.FPR_28940	0.0	913.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,3WHAH@541000|Ruminococcaceae	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
BIFPGKOA_00594	657322.FPR_28950	3.14e-192	534.0	COG0789@1|root,COG0789@2|Bacteria,1V6W4@1239|Firmicutes,24F6T@186801|Clostridia,3WKHZ@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator	hmrR	-	-	-	-	-	-	-	-	-	-	-	MerR_1
BIFPGKOA_00595	657322.FPR_28960	9.24e-186	518.0	COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,24GMY@186801|Clostridia,3WJXS@541000|Ruminococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
BIFPGKOA_00598	657322.FPR_28970	0.0	1186.0	COG2199@1|root,COG2199@2|Bacteria,1U78Z@1239|Firmicutes,25FRJ@186801|Clostridia,3WKMI@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
BIFPGKOA_00599	657322.FPR_28980	0.0	1098.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,3WGE8@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
BIFPGKOA_00600	657322.FPR_28990	1.11e-125	358.0	COG3707@1|root,COG3707@2|Bacteria,1V9FH@1239|Firmicutes,24JZU@186801|Clostridia,3WJ90@541000|Ruminococcaceae	186801|Clostridia	K	ANTAR domain protein	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
BIFPGKOA_00601	657322.FPR_29000	0.0	889.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,3WGBE@541000|Ruminococcaceae	186801|Clostridia	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
BIFPGKOA_00602	657322.FPR_29010	3.49e-161	469.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae	186801|Clostridia	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
BIFPGKOA_00603	657322.FPR_20860	9.12e-78	240.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WITY@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
BIFPGKOA_00604	657322.FPR_20870	8.82e-241	661.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WGTC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
BIFPGKOA_00605	657322.FPR_20880	2.35e-244	670.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WH83@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
BIFPGKOA_00606	657322.FPR_20890	0.0	936.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,3WHJ3@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type oligopeptide transport system periplasmic component	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
BIFPGKOA_00608	657322.FPR_20910	0.0	1136.0	COG4548@1|root,COG4548@2|Bacteria,1TS8V@1239|Firmicutes,249FH@186801|Clostridia,3WHZQ@541000|Ruminococcaceae	186801|Clostridia	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
BIFPGKOA_00609	657322.FPR_20920	2.18e-216	597.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,249C6@186801|Clostridia,3WH7J@541000|Ruminococcaceae	186801|Clostridia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
BIFPGKOA_00610	748224.HMPREF9436_02932	0.0	1239.0	COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1TT1Q@1239|Firmicutes,249N4@186801|Clostridia,3WHHS@541000|Ruminococcaceae	186801|Clostridia	C	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FMN_bind
BIFPGKOA_00611	657322.FPR_20940	1.6e-219	605.0	COG0583@1|root,COG0583@2|Bacteria,1TT5B@1239|Firmicutes,24G8Z@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BIFPGKOA_00612	657322.FPR_20950	7.19e-67	218.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGVP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
BIFPGKOA_00615	657322.FPR_24480	2.84e-204	565.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,3WGGC@541000|Ruminococcaceae	186801|Clostridia	C	domain protein	nfnA	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
BIFPGKOA_00616	657322.FPR_24470	0.0	922.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WGEA@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
BIFPGKOA_00617	657322.FPR_24460	1.92e-106	306.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia,3WKBA@541000|Ruminococcaceae	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
BIFPGKOA_00618	657322.FPR_24450	2.51e-74	223.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24NQK@186801|Clostridia,3WKX6@541000|Ruminococcaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
BIFPGKOA_00619	657322.FPR_24440	0.0	1063.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,3WH9C@541000|Ruminococcaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
BIFPGKOA_00620	748224.HMPREF9436_02996	0.0	2733.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,3WGJN@541000|Ruminococcaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
BIFPGKOA_00621	657322.FPR_24420	1.49e-251	690.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3WGBA@541000|Ruminococcaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
BIFPGKOA_00622	657322.FPR_24410	4.37e-131	379.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WGQW@541000|Ruminococcaceae	186801|Clostridia	M	Metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
BIFPGKOA_00623	657322.FPR_26130	9.42e-234	644.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia,3WIE9@541000|Ruminococcaceae	186801|Clostridia	D	Stage II sporulation protein D	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
BIFPGKOA_00624	748224.HMPREF9436_03164	4.69e-161	459.0	2DW9C@1|root,33Z5T@2|Bacteria,1VBX0@1239|Firmicutes,24Q8T@186801|Clostridia,3WQE2@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00625	718252.FP2_32150	9.45e-14	73.2	COG2755@1|root,COG2755@2|Bacteria,1UM8B@1239|Firmicutes,25GBV@186801|Clostridia,3WRMU@541000|Ruminococcaceae	186801|Clostridia	E	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
BIFPGKOA_00626	657322.FPR_26100	2.58e-192	535.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3WGWE@541000|Ruminococcaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
BIFPGKOA_00627	657322.FPR_26090	3.11e-278	766.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,3WGHH@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
BIFPGKOA_00629	657322.FPR_26070	1.23e-177	511.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,3WGCB@541000|Ruminococcaceae	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
BIFPGKOA_00630	657322.FPR_26060	8.73e-205	568.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,3WHNT@541000|Ruminococcaceae	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
BIFPGKOA_00631	657322.FPR_26050	1.33e-175	490.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,3WGK4@541000|Ruminococcaceae	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
BIFPGKOA_00632	657322.FPR_26040	7.73e-256	702.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia,3WHDV@541000|Ruminococcaceae	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	Diacid_rec,HTH_30
BIFPGKOA_00633	657322.FPR_26030	8.35e-164	458.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,3WHTI@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
BIFPGKOA_00634	657322.FPR_26020	1.37e-13	69.3	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3WG9P@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
BIFPGKOA_00635	748224.HMPREF9436_00857	4.18e-168	497.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,3WGW6@541000|Ruminococcaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
BIFPGKOA_00636	657322.FPR_05000	0.0	886.0	COG3581@1|root,COG3581@2|Bacteria,1TRVV@1239|Firmicutes,24947@186801|Clostridia,3WH15@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
BIFPGKOA_00637	657322.FPR_04990	1.38e-218	602.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes	1239|Firmicutes	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00638	657322.FPR_04980	0.0	1704.0	COG0480@1|root,COG3688@1|root,COG0480@2|Bacteria,COG3688@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,3WH08@541000|Ruminococcaceae	186801|Clostridia	J	elongation factor G	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
BIFPGKOA_00639	657322.FPR_04970	3.02e-199	553.0	COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,3WG7J@541000|Ruminococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
BIFPGKOA_00640	657322.FPR_04960	3.3e-180	501.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,249SD@186801|Clostridia,3WNRZ@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	-	-	1.5.1.38	ko:K19285	ko00740,ko01100,map00740,map01100	-	R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
BIFPGKOA_00641	657322.FPR_04950	9.48e-237	651.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,3WGP5@541000|Ruminococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
BIFPGKOA_00642	657322.FPR_04940	0.0	1652.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WGRT@541000|Ruminococcaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
BIFPGKOA_00643	748224.HMPREF9436_00122	4.25e-176	501.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3WGWJ@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
BIFPGKOA_00644	657322.FPR_28390	0.0	1016.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,3WGKF@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
BIFPGKOA_00646	1291050.JAGE01000001_gene1852	1.95e-95	292.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,25C41@186801|Clostridia	186801|Clostridia	L	Phage integrase SAM-like domain	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_5,Phage_integrase
BIFPGKOA_00647	657322.FPR_28420	0.0	1145.0	2EPQE@1|root,33HAZ@2|Bacteria,1VM8T@1239|Firmicutes,24EDI@186801|Clostridia	186801|Clostridia	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
BIFPGKOA_00649	657322.FPR_28460	3.61e-42	137.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
BIFPGKOA_00651	657322.FPR_28480	1.51e-155	436.0	2DRCF@1|root,33B7F@2|Bacteria,1VC9S@1239|Firmicutes,24RNI@186801|Clostridia	186801|Clostridia	S	SprT-like family	-	-	-	-	-	-	-	-	-	-	-	-	SprT-like
BIFPGKOA_00654	657322.FPR_02950	8.35e-27	100.0	COG1321@1|root,COG1321@2|Bacteria,1VH4R@1239|Firmicutes,24SPR@186801|Clostridia,3WMMY@541000|Ruminococcaceae	186801|Clostridia	K	Iron dependent repressor, N-terminal DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repress,MarR_2
BIFPGKOA_00655	657322.FPR_02960	4.26e-229	633.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	envE	-	3.1.4.46,3.2.1.18,3.2.1.8	ko:K01126,ko:K01181,ko:K01186	ko00511,ko00564,ko00600,ko04142,map00511,map00564,map00600,map04142	-	R01030,R01470,R04018	RC00017,RC00028,RC00077,RC00425	ko00000,ko00001,ko01000,ko02042	-	GH33	-	GHL10,Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin,SLH
BIFPGKOA_00656	657322.FPR_02970	0.0	1152.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,3WH64@541000|Ruminococcaceae	186801|Clostridia	IQ	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
BIFPGKOA_00657	657322.FPR_02980	9.93e-286	784.0	COG1143@1|root,COG1145@1|root,COG1143@2|Bacteria,COG1145@2|Bacteria,1VE78@1239|Firmicutes,25DNA@186801|Clostridia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
BIFPGKOA_00658	657322.FPR_02990	1.7e-213	592.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
BIFPGKOA_00659	657322.FPR_03000	0.0	1236.0	28N4Z@1|root,2ZBA9@2|Bacteria,1V60W@1239|Firmicutes,24HJB@186801|Clostridia,3WP63@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00660	657322.FPR_03010	0.0	1389.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGVQ@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
BIFPGKOA_00661	657322.FPR_03020	0.0	947.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia,3WGMX@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain protein	-	-	3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R10223,R11262	RC00477	ko00000,ko00001,ko01000,ko03016	-	GH13	-	Alpha-amylase,Alpha-amylase_C,DUF1653,Malt_amylase_C
BIFPGKOA_00662	657322.FPR_09690	2.29e-153	431.0	COG1309@1|root,COG1309@2|Bacteria,1VJYD@1239|Firmicutes,24SNN@186801|Clostridia,3WP6U@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BIFPGKOA_00663	657322.FPR_09680	2.14e-175	488.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,3WH3N@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
BIFPGKOA_00664	657322.FPR_09670	6.24e-168	470.0	COG1349@1|root,COG1349@2|Bacteria,1V25D@1239|Firmicutes,24GWY@186801|Clostridia,3WRTQ@541000|Ruminococcaceae	186801|Clostridia	K	DeoR C terminal sensor domain	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
BIFPGKOA_00665	518637.EUBIFOR_02508	1.78e-269	741.0	COG1063@1|root,COG1063@2|Bacteria,1TQ60@1239|Firmicutes,3VNX5@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
BIFPGKOA_00666	1408437.JNJN01000011_gene1146	2.87e-124	365.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,25VK7@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
BIFPGKOA_00667	657322.FPR_09650	0.0	898.0	COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia,3WKXE@541000|Ruminococcaceae	186801|Clostridia	H	PRD domain	-	-	-	ko:K03483	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
BIFPGKOA_00668	657322.FPR_09640	0.0	1040.0	COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1TPE3@1239|Firmicutes,24A04@186801|Clostridia,3WN1N@541000|Ruminococcaceae	186801|Clostridia	G	PTS system	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
BIFPGKOA_00669	657322.FPR_09630	1.88e-52	165.0	COG1925@1|root,COG1925@2|Bacteria,1VNNY@1239|Firmicutes	1239|Firmicutes	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
BIFPGKOA_00670	657322.FPR_29560	1.5e-202	567.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,3WGGE@541000|Ruminococcaceae	186801|Clostridia	C	Acetyl-CoA hydrolase/transferase C-terminal domain	cat	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
BIFPGKOA_00671	657322.FPR_29550	3.44e-268	738.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,3WGFR@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
BIFPGKOA_00672	657322.FPR_29530	0.0	983.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
BIFPGKOA_00673	748224.HMPREF9436_02975	6.19e-107	311.0	COG1309@1|root,COG1309@2|Bacteria,1UYIP@1239|Firmicutes,249K5@186801|Clostridia,3WJ60@541000|Ruminococcaceae	186801|Clostridia	K	dihydroxyacetone kinase regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
BIFPGKOA_00675	657322.FPR_29500	4.62e-183	510.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,3WGT7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
BIFPGKOA_00676	657322.FPR_29490	1.1e-184	514.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,3WGZ7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
BIFPGKOA_00677	657322.FPR_29480	4.1e-290	793.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,3WH60@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
BIFPGKOA_00678	657322.FPR_29470	3.93e-99	288.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3WII3@541000|Ruminococcaceae	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
BIFPGKOA_00679	657322.FPR_29460	1.61e-313	853.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,3WGF6@541000|Ruminococcaceae	186801|Clostridia	P	Cystathionine beta-lyase family protein involved in aluminum resistance	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
BIFPGKOA_00680	748224.HMPREF9436_02966	3.48e-129	372.0	2BBZZ@1|root,325IJ@2|Bacteria,1URJQ@1239|Firmicutes,259G0@186801|Clostridia,3WQ3T@541000|Ruminococcaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
BIFPGKOA_00681	657322.FPR_29440	5.01e-151	434.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3WG85@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
BIFPGKOA_00682	657322.FPR_24700	1.44e-196	550.0	COG1589@1|root,COG1589@2|Bacteria,1UHVF@1239|Firmicutes,25E4A@186801|Clostridia,3WIXM@541000|Ruminococcaceae	186801|Clostridia	M	Putative stage IV sporulation protein YqfD	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
BIFPGKOA_00683	657322.FPR_21760	2.67e-307	838.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,3WGW3@541000|Ruminococcaceae	186801|Clostridia	F	pyrimidine-nucleoside phosphorylase	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
BIFPGKOA_00684	657322.FPR_21750	5.35e-290	791.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,3WI1M@541000|Ruminococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
BIFPGKOA_00685	657322.FPR_21740	0.0	1108.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3WH1A@541000|Ruminococcaceae	186801|Clostridia	G	Pyruvate kinase	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
BIFPGKOA_00686	657322.FPR_21730	4.92e-104	300.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,3WJQ9@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
BIFPGKOA_00687	657322.FPR_21720	5.09e-202	559.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,248PG@186801|Clostridia,3WRIK@541000|Ruminococcaceae	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
BIFPGKOA_00688	657322.FPR_21710	7.18e-234	644.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3WHIU@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	scrR	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
BIFPGKOA_00690	748224.HMPREF9436_00914	7.15e-161	460.0	2DV4W@1|root,33U20@2|Bacteria,1VUE7@1239|Firmicutes,25097@186801|Clostridia,3WP8N@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00691	748224.HMPREF9436_00913	1.52e-141	421.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3WG86@541000|Ruminococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
BIFPGKOA_00692	657322.FPR_30530	2.6e-181	504.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,3WH3Y@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
BIFPGKOA_00693	657322.FPR_30540	7.01e-213	588.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,3WGWA@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
BIFPGKOA_00694	657322.FPR_30550	1.2e-263	721.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3WGVU@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
BIFPGKOA_00695	657322.FPR_30560	1.01e-249	685.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3WGMR@541000|Ruminococcaceae	186801|Clostridia	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
BIFPGKOA_00696	657322.FPR_30570	9.18e-290	789.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,3WGAU@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
BIFPGKOA_00697	657322.FPR_30580	5.34e-64	196.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,3WKMJ@541000|Ruminococcaceae	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
BIFPGKOA_00700	657322.FPR_30610	0.0	865.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,3WG8G@541000|Ruminococcaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
BIFPGKOA_00701	657322.FPR_30620	9.9e-281	768.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WGCI@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
BIFPGKOA_00702	748224.HMPREF9436_01574	9.19e-133	384.0	COG0860@1|root,COG0860@2|Bacteria,1V4XQ@1239|Firmicutes,24KYC@186801|Clostridia,3WRIQ@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
BIFPGKOA_00703	657322.FPR_10970	0.0	1041.0	COG3675@1|root,COG3675@2|Bacteria,1VCNZ@1239|Firmicutes,24U5I@186801|Clostridia,3WQ4X@541000|Ruminococcaceae	186801|Clostridia	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
BIFPGKOA_00704	657322.FPR_10980	1.19e-92	271.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia,3WMN1@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
BIFPGKOA_00705	657322.FPR_10990	7.56e-36	121.0	2CHQ1@1|root,32YKW@2|Bacteria,1VG7A@1239|Firmicutes,24RG3@186801|Clostridia,3WKVF@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00708	748224.HMPREF9436_01968	4.2e-117	335.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,3WIS5@541000|Ruminococcaceae	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
BIFPGKOA_00709	657322.FPR_11040	5.88e-131	373.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,3WIM6@541000|Ruminococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
BIFPGKOA_00710	657322.FPR_11050	2.67e-251	689.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,3WGXE@541000|Ruminococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
BIFPGKOA_00711	657322.FPR_11060	5.86e-227	623.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,3WGYH@541000|Ruminococcaceae	186801|Clostridia	J	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
BIFPGKOA_00712	657322.FPR_11070	1.45e-196	545.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WG9K@541000|Ruminococcaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
BIFPGKOA_00713	657322.FPR_11080	2.18e-215	595.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WG8V@541000|Ruminococcaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	cbiO	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
BIFPGKOA_00714	657322.FPR_11090	8.63e-185	514.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,3WGYM@541000|Ruminococcaceae	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
BIFPGKOA_00715	657322.FPR_11100	1.33e-177	495.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,3WIKF@541000|Ruminococcaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
BIFPGKOA_00716	657322.FPR_02900	1.94e-141	399.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,3WJ9N@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
BIFPGKOA_00717	657322.FPR_02890	5.97e-138	390.0	COG0572@1|root,COG0572@2|Bacteria,1V1DZ@1239|Firmicutes,24FY8@186801|Clostridia,3WK6K@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PRK
BIFPGKOA_00718	748224.HMPREF9436_02509	7.59e-273	744.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02615	GDP_Man_Dehyd
BIFPGKOA_00720	657322.FPR_02860	2.06e-234	643.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,3WGZV@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
BIFPGKOA_00721	657322.FPR_02850	6.52e-217	598.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,3WGQ3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
BIFPGKOA_00722	657322.FPR_02840	4.51e-192	532.0	COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,249T1@186801|Clostridia,3WMBE@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferase family 21	-	-	-	ko:K07011,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,Methyltransf_23
BIFPGKOA_00723	657322.FPR_02830	0.0	1584.0	COG1216@1|root,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
BIFPGKOA_00724	748224.HMPREF9436_02515	7.87e-209	582.0	COG2385@1|root,COG2385@2|Bacteria	2|Bacteria	D	sporulation resulting in formation of a cellular spore	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	CinA,MoCF_biosynth,Sortase,SpoIID
BIFPGKOA_00726	657322.FPR_24380	4e-173	482.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,3WGF5@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
BIFPGKOA_00727	657322.FPR_24370	1.04e-117	338.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3WIRX@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
BIFPGKOA_00728	657322.FPR_24360	1.33e-166	466.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,3WGUN@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
BIFPGKOA_00729	657322.FPR_24350	2.39e-166	465.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia,3WGU3@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
BIFPGKOA_00730	657322.FPR_24340	3.42e-52	187.0	COG3064@1|root,COG3064@2|Bacteria,1VASR@1239|Firmicutes,24IM3@186801|Clostridia	186801|Clostridia	M	Host cell surface-exposed lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_Ltp
BIFPGKOA_00732	657322.FPR_24320	1.68e-177	494.0	COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,24916@186801|Clostridia,3WSIK@541000|Ruminococcaceae	186801|Clostridia	K	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K07699	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Spo0A_C
BIFPGKOA_00733	657322.FPR_24310	7.05e-289	789.0	COG3975@1|root,COG3975@2|Bacteria,1UHV7@1239|Firmicutes,25E3Y@186801|Clostridia,3WSNP@541000|Ruminococcaceae	186801|Clostridia	S	stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
BIFPGKOA_00734	657322.FPR_24300	3.87e-262	719.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,3WG91@541000|Ruminococcaceae	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
BIFPGKOA_00735	657322.FPR_24290	1.12e-241	663.0	2E0TS@1|root,32WBE@2|Bacteria,1VBFI@1239|Firmicutes,24PTN@186801|Clostridia,3WIIS@541000|Ruminococcaceae	186801|Clostridia	S	Prokaryotic RING finger family 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF2628,Prok-RING_1
BIFPGKOA_00736	657322.FPR_24280	2.97e-211	583.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,3WH3P@541000|Ruminococcaceae	186801|Clostridia	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
BIFPGKOA_00737	657322.FPR_24270	1.17e-52	176.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia,3WHPA@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	napA	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
BIFPGKOA_00738	357809.Cphy_3217	8.64e-186	533.0	COG5434@1|root,COG5434@2|Bacteria,1V4PZ@1239|Firmicutes,24CQH@186801|Clostridia,220B6@1506553|Lachnoclostridium	186801|Clostridia	G	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
BIFPGKOA_00739	1410612.JNKO01000010_gene439	1.36e-57	179.0	COG3254@1|root,COG3254@2|Bacteria,1VA1C@1239|Firmicutes,24JG9@186801|Clostridia	186801|Clostridia	G	Involved in the anomeric conversion of L-rhamnose	rhaM	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
BIFPGKOA_00740	1280682.AUKA01000019_gene1133	1.81e-216	601.0	COG4225@1|root,COG4225@2|Bacteria,1UYKV@1239|Firmicutes,2494H@186801|Clostridia,4BY8Z@830|Butyrivibrio	186801|Clostridia	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
BIFPGKOA_00741	1163671.JAGI01000001_gene317	1.06e-129	375.0	COG0726@1|root,COG0726@2|Bacteria,1U0B6@1239|Firmicutes,24895@186801|Clostridia,36EUF@31979|Clostridiaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
BIFPGKOA_00742	411470.RUMGNA_02711	0.0	1260.0	COG2755@1|root,COG3401@1|root,COG2755@2|Bacteria,COG3401@2|Bacteria,1TQR3@1239|Firmicutes,24896@186801|Clostridia	186801|Clostridia	G	FG-GAP repeat protein	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	Dockerin_1,Lipase_GDSL_2,RicinB_lectin_2,SLH
BIFPGKOA_00743	411470.RUMGNA_02712	2.15e-224	635.0	COG1653@1|root,COG1653@2|Bacteria,1TTUX@1239|Firmicutes,25INP@186801|Clostridia,3Y22U@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00744	1449050.JNLE01000003_gene2298	4.18e-145	417.0	COG0395@1|root,COG0395@2|Bacteria,1TS0D@1239|Firmicutes,248YI@186801|Clostridia,36H21@31979|Clostridiaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
BIFPGKOA_00745	411470.RUMGNA_02714	3.87e-154	441.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,247UA@186801|Clostridia,3Y1CA@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
BIFPGKOA_00746	657322.FPR_05410	0.0	1134.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,3WGIC@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
BIFPGKOA_00747	657322.FPR_05420	0.0	867.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WH3J@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
BIFPGKOA_00748	657322.FPR_05430	0.0	981.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia,3WHJQ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
BIFPGKOA_00749	657322.FPR_05440	0.0	1209.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,3WHCI@541000|Ruminococcaceae	186801|Clostridia	G	PTS system	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
BIFPGKOA_00750	657322.FPR_05450	2.32e-204	566.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,3WH8H@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
BIFPGKOA_00751	657322.FPR_05460	7.63e-169	473.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia,3WIVJ@541000|Ruminococcaceae	186801|Clostridia	K	COG COG1349 Transcriptional regulators of sugar metabolism	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
BIFPGKOA_00752	657322.FPR_05470	5.96e-122	360.0	COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,248K3@186801|Clostridia,3WNUW@541000|Ruminococcaceae	186801|Clostridia	E	Dipeptidase	pepD	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
BIFPGKOA_00753	657322.FPR_04750	1.55e-150	424.0	COG1191@1|root,COG1191@2|Bacteria,1V296@1239|Firmicutes,24GTU@186801|Clostridia,3WGPV@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
BIFPGKOA_00754	657322.FPR_04760	3.93e-99	288.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,3WJC6@541000|Ruminococcaceae	186801|Clostridia	T	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
BIFPGKOA_00755	657322.FPR_04770	6.43e-66	201.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,3WKRQ@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
BIFPGKOA_00756	657322.FPR_04780	7.83e-284	778.0	COG0285@1|root,COG0285@2|Bacteria	2|Bacteria	H	dihydrofolate synthase activity	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,Mur_ligase_C,Mur_ligase_M
BIFPGKOA_00757	748224.HMPREF9436_02843	5.52e-65	202.0	COG5652@1|root,COG5652@2|Bacteria,1VBNW@1239|Firmicutes,25827@186801|Clostridia,3WKKI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
BIFPGKOA_00758	657322.FPR_04800	0.0	1855.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3WHFT@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
BIFPGKOA_00759	657322.FPR_04810	2.1e-250	685.0	COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,2502I@186801|Clostridia,3WSPW@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BIFPGKOA_00760	657322.FPR_04820	0.0	974.0	COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,24917@186801|Clostridia,3WHMM@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
BIFPGKOA_00761	1236517.BAKO01000021_gene2002	1.12e-06	55.1	COG1215@1|root,COG1215@2|Bacteria,4NKAV@976|Bacteroidetes,2G0U1@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BIFPGKOA_00763	657322.FPR_10370	3.7e-141	399.0	2B66C@1|root,31Z3H@2|Bacteria,1V6U0@1239|Firmicutes,24ICU@186801|Clostridia,3WM7U@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00765	657322.FPR_10240	1.74e-224	618.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WN2S@541000|Ruminococcaceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
BIFPGKOA_00766	657322.FPR_10230	7.23e-263	720.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WHP6@541000|Ruminococcaceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
BIFPGKOA_00767	718252.FP2_31120	3.3e-228	632.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WIY9@541000|Ruminococcaceae	186801|Clostridia	P	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
BIFPGKOA_00768	748224.HMPREF9436_00016	1.15e-193	540.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WK10@541000|Ruminococcaceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
BIFPGKOA_00769	718252.FP2_31140	0.0	988.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,3WSCF@541000|Ruminococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
BIFPGKOA_00770	657322.FPR_10200	3.67e-69	216.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,3WGIP@541000|Ruminococcaceae	186801|Clostridia	G	Transketolase, pyridine binding domain protein	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
BIFPGKOA_00771	1347369.CCAD010000081_gene2629	0.0	1257.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes	2|Bacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
BIFPGKOA_00772	658086.HMPREF0994_00879	1.09e-126	404.0	COG2207@1|root,COG2207@2|Bacteria,1UY4J@1239|Firmicutes,24BXQ@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
BIFPGKOA_00773	658086.HMPREF0994_00390	1.46e-160	468.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_00774	658086.HMPREF0994_02324	6.21e-227	657.0	COG3250@1|root,COG3250@2|Bacteria,1TTVZ@1239|Firmicutes,24FJ0@186801|Clostridia	186801|Clostridia	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
BIFPGKOA_00775	748224.HMPREF9436_00402	2.27e-201	561.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,24997@186801|Clostridia,3WJ9D@541000|Ruminococcaceae	186801|Clostridia	S	G5 domain	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
BIFPGKOA_00776	657322.FPR_13530	0.0	1006.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,SLH
BIFPGKOA_00777	411483.FAEPRAA2165_00757	1.79e-32	126.0	2EMH0@1|root,33F5M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
BIFPGKOA_00778	657322.FPR_13550	1.25e-243	671.0	COG5492@1|root,COG5492@2|Bacteria,1VKK8@1239|Firmicutes	1239|Firmicutes	N	Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,Laminin_G_3,SLH
BIFPGKOA_00780	657322.FPR_13570	7.23e-93	271.0	COG3108@1|root,COG3108@2|Bacteria,1VFRJ@1239|Firmicutes,24R9N@186801|Clostridia	186801|Clostridia	M	Peptidase M15A	-	-	3.4.17.14	ko:K08640	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M15_3
BIFPGKOA_00781	748224.HMPREF9436_00408	1.29e-31	112.0	2DRAZ@1|root,33B0U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00782	657322.FPR_13590	6.31e-51	161.0	2DRCI@1|root,33B7V@2|Bacteria,1VKC1@1239|Firmicutes,24S49@186801|Clostridia,3WQWC@541000|Ruminococcaceae	186801|Clostridia	S	SPP1 phage holin	-	-	-	-	-	-	-	-	-	-	-	-	Holin_SPP1
BIFPGKOA_00783	657322.FPR_26420	2.59e-170	475.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,3WJ3Y@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	HHH,RadC
BIFPGKOA_00784	657322.FPR_26410	3.89e-242	664.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,3WH5D@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
BIFPGKOA_00785	657322.FPR_26400	0.0	885.0	COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,24AAW@186801|Clostridia,3WIIR@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
BIFPGKOA_00786	657322.FPR_26390	1.44e-167	468.0	COG0745@1|root,COG0745@2|Bacteria,1TYPK@1239|Firmicutes,247Y9@186801|Clostridia,3WIQ8@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
BIFPGKOA_00787	411483.FAEPRAA2165_01031	6.7e-212	586.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,3WGJ6@541000|Ruminococcaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	bcrA_2	-	-	ko:K01990,ko:K20459	ko02010,map02010	M00254,M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
BIFPGKOA_00788	657322.FPR_26370	1.05e-174	487.0	COG4200@1|root,COG4200@2|Bacteria,1V273@1239|Firmicutes,24HVF@186801|Clostridia,3WKNS@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K20460	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
BIFPGKOA_00789	657322.FPR_26360	6.59e-171	477.0	COG4200@1|root,COG4200@2|Bacteria,1TSD5@1239|Firmicutes,24DU9@186801|Clostridia,3WJ80@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K20461	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
BIFPGKOA_00790	657322.FPR_26350	4.73e-88	259.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,3WJYM@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
BIFPGKOA_00791	657322.FPR_26340	5.64e-90	276.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3WGVH@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
BIFPGKOA_00792	1449050.JNLE01000005_gene4930	2.16e-58	204.0	COG5002@1|root,COG5002@2|Bacteria,1URKI@1239|Firmicutes,248WK@186801|Clostridia,36HFT@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
BIFPGKOA_00793	1449050.JNLE01000005_gene4929	6.74e-66	210.0	COG0745@1|root,COG0745@2|Bacteria,1UZIS@1239|Firmicutes,24CCE@186801|Clostridia,36J64@31979|Clostridiaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
BIFPGKOA_00794	665956.HMPREF1032_00785	8.99e-56	213.0	COG1653@1|root,COG1653@2|Bacteria,1V04I@1239|Firmicutes,247SU@186801|Clostridia,3WJG1@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
BIFPGKOA_00795	1414720.CBYM010000012_gene2601	4.65e-84	261.0	COG1175@1|root,COG1175@2|Bacteria,1TQTC@1239|Firmicutes,24AQX@186801|Clostridia,36GI8@31979|Clostridiaceae	186801|Clostridia	G	ABC transporter, permease protein	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
BIFPGKOA_00796	665956.HMPREF1032_00783	2.58e-112	332.0	COG0395@1|root,COG0395@2|Bacteria,1TS82@1239|Firmicutes,2488S@186801|Clostridia,3WHSW@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
BIFPGKOA_00797	1297617.JPJD01000028_gene2274	7.73e-09	66.6	COG0845@1|root,COG0845@2|Bacteria,1UZZV@1239|Firmicutes,24AQV@186801|Clostridia,2699W@186813|unclassified Clostridiales	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
BIFPGKOA_00798	742735.HMPREF9467_04834	0.000183	51.2	2E1BR@1|root,32WRK@2|Bacteria,1V7RQ@1239|Firmicutes,249B7@186801|Clostridia,21ZBN@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00799	657322.FPR_06050	8.63e-31	118.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WHF4@541000|Ruminococcaceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_00800	657322.FPR_06040	2.42e-146	412.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,3WGYU@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
BIFPGKOA_00801	657322.FPR_06030	1.79e-105	304.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3WJA1@541000|Ruminococcaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
BIFPGKOA_00802	657322.FPR_06020	1.89e-158	445.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,3WJ9X@541000|Ruminococcaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
BIFPGKOA_00803	657322.FPR_06010	8.69e-96	279.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3WK7G@541000|Ruminococcaceae	186801|Clostridia	S	Hydrolase, P-loop family	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
BIFPGKOA_00804	657322.FPR_06000	2.15e-281	770.0	2DF4U@1|root,2ZQGY@2|Bacteria,1UFDY@1239|Firmicutes,251JV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00805	657322.FPR_05990	2.85e-277	759.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,3WJ15@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
BIFPGKOA_00806	657322.FPR_05980	3.09e-133	378.0	COG1116@1|root,COG1116@2|Bacteria,1VAD8@1239|Firmicutes,24GFE@186801|Clostridia,3WK2M@541000|Ruminococcaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
BIFPGKOA_00807	657322.FPR_05970	9.19e-168	470.0	COG0600@1|root,COG0600@2|Bacteria,1V73W@1239|Firmicutes,24A2R@186801|Clostridia,3WIHB@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran,BPD_transp_1
BIFPGKOA_00808	748224.HMPREF9436_01849	2.94e-212	597.0	COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,248I0@186801|Clostridia,3WI3G@541000|Ruminococcaceae	186801|Clostridia	E	Component of the transport system for branched-chain amino acids	brnQ	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
BIFPGKOA_00809	657322.FPR_05950	7.84e-92	268.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,3WJTP@541000|Ruminococcaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
BIFPGKOA_00810	657322.FPR_05940	1.14e-08	55.1	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,3WH4R@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
BIFPGKOA_00811	657322.FPR_28210	6.12e-184	511.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3WH9D@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter, ATP-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
BIFPGKOA_00812	657322.FPR_28220	0.0	872.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_00813	748224.HMPREF9436_00126	0.0	1442.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3WG9R@541000|Ruminococcaceae	186801|Clostridia	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
BIFPGKOA_00814	657322.FPR_28250	1.66e-210	581.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,3WGKR@541000|Ruminococcaceae	186801|Clostridia	S	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
BIFPGKOA_00815	657322.FPR_28260	5.26e-58	179.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,3WKHY@541000|Ruminococcaceae	186801|Clostridia	S	TSCPD domain	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
BIFPGKOA_00816	657322.FPR_28270	0.0	1224.0	COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia,3WGYT@541000|Ruminococcaceae	186801|Clostridia	S	MCRA family	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
BIFPGKOA_00818	657322.FPR_15620	0.0	1006.0	COG1904@1|root,COG1904@2|Bacteria,1TRI0@1239|Firmicutes,248C0@186801|Clostridia,3WH1J@541000|Ruminococcaceae	186801|Clostridia	G	glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
BIFPGKOA_00819	657322.FPR_15610	4.7e-205	568.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
BIFPGKOA_00820	657322.FPR_15600	0.0	1140.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,3WH6G@541000|Ruminococcaceae	186801|Clostridia	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
BIFPGKOA_00821	657322.FPR_15590	1.55e-72	219.0	COG3976@1|root,COG3976@2|Bacteria	2|Bacteria	S	FMN binding	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,Oxidored_FMN
BIFPGKOA_00822	657322.FPR_15580	1.71e-241	663.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,247Q4@186801|Clostridia,3WIHM@541000|Ruminococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
BIFPGKOA_00823	657322.FPR_15570	7.7e-69	208.0	COG2198@1|root,COG2198@2|Bacteria,1TUB8@1239|Firmicutes,24W35@186801|Clostridia	186801|Clostridia	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
BIFPGKOA_00825	411483.FAEPRAA2165_02541	6e-49	156.0	2CZEX@1|root,32T68@2|Bacteria,1VB18@1239|Firmicutes,24MZP@186801|Clostridia,3WPUQ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00826	657322.FPR_21150	3.85e-163	464.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3WH1H@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
BIFPGKOA_00827	657322.FPR_21160	4.57e-90	264.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,3WJN8@541000|Ruminococcaceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
BIFPGKOA_00829	657322.FPR_21180	0.0	1006.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,3WGN3@541000|Ruminococcaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
BIFPGKOA_00830	657322.FPR_21190	4.12e-170	475.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3WHDN@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
BIFPGKOA_00831	657322.FPR_21200	4.33e-57	177.0	COG4115@1|root,COG4115@2|Bacteria,1VAM5@1239|Firmicutes,24N6K@186801|Clostridia	186801|Clostridia	S	YoeB-like toxin of bacterial type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	YoeB_toxin
BIFPGKOA_00832	657322.FPR_21210	3.28e-52	164.0	COG2161@1|root,COG2161@2|Bacteria,1VCZ4@1239|Firmicutes,24PB9@186801|Clostridia	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
BIFPGKOA_00833	657322.FPR_21220	0.0	902.0	COG3048@1|root,COG3048@2|Bacteria,1TPAH@1239|Firmicutes,249NA@186801|Clostridia,3WNIF@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the serine threonine dehydratase family. DsdA subfamily	dsdA	-	4.3.1.18	ko:K01753	ko00260,map00260	-	R00221	RC02600	ko00000,ko00001,ko01000	-	-	-	PALP
BIFPGKOA_00835	657322.FPR_21240	1.64e-293	797.0	COG1312@1|root,COG1312@2|Bacteria,1TP5F@1239|Firmicutes,247RB@186801|Clostridia,3WGRF@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the dehydration of D-mannonate	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
BIFPGKOA_00836	748224.HMPREF9436_01479	4.37e-270	761.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3WG9B@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
BIFPGKOA_00837	657322.FPR_31430	2.02e-101	295.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3WJWG@541000|Ruminococcaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
BIFPGKOA_00838	657322.FPR_31420	5.21e-226	622.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,3WGKV@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
BIFPGKOA_00839	657322.FPR_31410	6.07e-187	520.0	COG0561@1|root,COG0561@2|Bacteria,1V8Z5@1239|Firmicutes	1239|Firmicutes	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
BIFPGKOA_00840	657322.FPR_31400	9.19e-76	226.0	COG1555@1|root,COG1555@2|Bacteria,1UQNT@1239|Firmicutes,258F9@186801|Clostridia,3WMJR@541000|Ruminococcaceae	186801|Clostridia	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
BIFPGKOA_00841	657322.FPR_31390	0.0	1524.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3WGAB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
BIFPGKOA_00842	657322.FPR_31380	5.9e-120	343.0	COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,24RH8@186801|Clostridia,3WPUG@541000|Ruminococcaceae	186801|Clostridia	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
BIFPGKOA_00843	657322.FPR_31370	1.25e-113	326.0	COG1994@1|root,COG1994@2|Bacteria,1VK5P@1239|Firmicutes,24UYF@186801|Clostridia	186801|Clostridia	S	Peptidase M50	-	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M50
BIFPGKOA_00844	657322.FPR_03580	2.97e-258	712.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,3WGZM@541000|Ruminococcaceae	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
BIFPGKOA_00845	657322.FPR_03570	2.21e-139	395.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,24J91@186801|Clostridia,3WJSP@541000|Ruminococcaceae	186801|Clostridia	S	stage II sporulation protein R	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
BIFPGKOA_00846	657322.FPR_03560	3.55e-109	314.0	COG3409@1|root,COG3409@2|Bacteria,1VMBN@1239|Firmicutes,24V9S@186801|Clostridia	186801|Clostridia	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
BIFPGKOA_00847	411483.FAEPRAA2165_03180	1.25e-227	633.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,3WH9B@541000|Ruminococcaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
BIFPGKOA_00848	748224.HMPREF9436_02385	0.0	1025.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,3WG9M@541000|Ruminococcaceae	186801|Clostridia	L	exonuclease SbcC	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
BIFPGKOA_00850	748224.HMPREF9436_02387	4.45e-46	148.0	COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,24QV3@186801|Clostridia,3WKST@541000|Ruminococcaceae	186801|Clostridia	S	Transcriptional Coactivator p15 (PC4)	-	-	-	-	-	-	-	-	-	-	-	-	PC4
BIFPGKOA_00851	748224.HMPREF9436_02388	1.48e-131	374.0	COG3481@1|root,COG3481@2|Bacteria,1TQEK@1239|Firmicutes,24BRR@186801|Clostridia,3WIKZ@541000|Ruminococcaceae	186801|Clostridia	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
BIFPGKOA_00852	657322.FPR_03490	3.92e-41	137.0	2AIN5@1|root,3194H@2|Bacteria,1V6U3@1239|Firmicutes,24JK0@186801|Clostridia,3WJU6@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3842)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3842
BIFPGKOA_00853	657322.FPR_21080	6.86e-276	756.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3WHC9@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
BIFPGKOA_00854	657322.FPR_21070	3.74e-210	581.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,3WH2P@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
BIFPGKOA_00855	657322.FPR_21060	2.58e-293	801.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3WGG4@541000|Ruminococcaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
BIFPGKOA_00856	748224.HMPREF9436_03007	9.51e-88	259.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia,3WK80@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
BIFPGKOA_00857	657322.FPR_21040	0.0	1620.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,3WHIF@541000|Ruminococcaceae	186801|Clostridia	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
BIFPGKOA_00859	657322.FPR_21020	1.3e-134	397.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3WGTX@541000|Ruminococcaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
BIFPGKOA_00860	657322.FPR_16430	5.22e-117	334.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24FQH@186801|Clostridia,3WIDZ@541000|Ruminococcaceae	186801|Clostridia	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
BIFPGKOA_00861	657322.FPR_16420	3.2e-242	665.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,3WG9U@541000|Ruminococcaceae	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
BIFPGKOA_00862	657322.FPR_16410	1.72e-123	353.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,3WJPD@541000|Ruminococcaceae	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
BIFPGKOA_00865	657322.FPR_16380	1.48e-114	328.0	COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,24MBJ@186801|Clostridia,3WRU8@541000|Ruminococcaceae	186801|Clostridia	K	Putative ATPase subunit of terminase (gpP-like)	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BIFPGKOA_00866	657322.FPR_16370	5.43e-214	598.0	COG3206@1|root,COG3206@2|Bacteria,1V8AX@1239|Firmicutes,25EXZ@186801|Clostridia,3WJXV@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
BIFPGKOA_00867	657322.FPR_16360	2.83e-201	557.0	COG1028@1|root,COG1028@2|Bacteria,1TQ3V@1239|Firmicutes,24ARQ@186801|Clostridia,3WIKB@541000|Ruminococcaceae	186801|Clostridia	IQ	short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
BIFPGKOA_00869	742735.HMPREF9467_05030	1.33e-41	146.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
BIFPGKOA_00870	657322.FPR_30730	6.19e-56	180.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,3WI66@541000|Ruminococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
BIFPGKOA_00872	657322.FPR_30710	7.88e-116	332.0	2DN4N@1|root,32UIA@2|Bacteria,1VA2T@1239|Firmicutes,24JJM@186801|Clostridia,3WJZR@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2812)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2812
BIFPGKOA_00873	657322.FPR_30700	1.17e-67	205.0	COG1695@1|root,COG1695@2|Bacteria,1V9XX@1239|Firmicutes,24RE5@186801|Clostridia,3WK2V@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
BIFPGKOA_00874	748224.HMPREF9436_01579	6.24e-212	588.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,3WHAN@541000|Ruminococcaceae	186801|Clostridia	T	phosphate starvation-inducible protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
BIFPGKOA_00875	657322.FPR_30670	1.95e-114	328.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,3WIDY@541000|Ruminococcaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
BIFPGKOA_00876	411483.FAEPRAA2165_02333	1.09e-199	555.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,3WGJ2@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
BIFPGKOA_00877	657322.FPR_30650	6.35e-176	490.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,3WJ6A@541000|Ruminococcaceae	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
BIFPGKOA_00878	657322.FPR_30640	0.0	1410.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,3WGD7@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
BIFPGKOA_00879	657322.FPR_12300	4.21e-111	320.0	COG1329@1|root,COG1329@2|Bacteria,1VAA0@1239|Firmicutes,24P60@186801|Clostridia,3WK1A@541000|Ruminococcaceae	186801|Clostridia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
BIFPGKOA_00880	657322.FPR_12290	0.0	869.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WH4B@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_00883	657322.FPR_12270	8.48e-215	594.0	COG0544@1|root,COG0544@2|Bacteria	2|Bacteria	D	peptidyl-prolyl cis-trans isomerase activity	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
BIFPGKOA_00884	657322.FPR_12260	6.39e-157	440.0	COG0398@1|root,COG0398@2|Bacteria,1V7VE@1239|Firmicutes,24NGJ@186801|Clostridia	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
BIFPGKOA_00885	657322.FPR_12250	3.5e-250	685.0	COG0847@1|root,COG0847@2|Bacteria,1UK7S@1239|Firmicutes,25FPM@186801|Clostridia,3WSNQ@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
BIFPGKOA_00886	657322.FPR_12240	6.15e-195	540.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,248MW@186801|Clostridia,3WIKA@541000|Ruminococcaceae	186801|Clostridia	S	Cof-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
BIFPGKOA_00887	657322.FPR_12410	6.81e-111	317.0	28YYK@1|root,2ZKRH@2|Bacteria,1W3K6@1239|Firmicutes,255EI@186801|Clostridia,3WR29@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00888	657322.FPR_12400	2.49e-297	810.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3WG87@541000|Ruminococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
BIFPGKOA_00889	748224.HMPREF9436_00298	1.87e-102	296.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3WITG@541000|Ruminococcaceae	186801|Clostridia	C	Fe-S iron-sulfur cluster assembly protein, NifU family	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
BIFPGKOA_00890	657322.FPR_12380	0.0	987.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3WHAV@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
BIFPGKOA_00891	748224.HMPREF9436_02206	0.0	908.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia,3WH2V@541000|Ruminococcaceae	186801|Clostridia	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
BIFPGKOA_00892	657322.FPR_12360	2.68e-254	698.0	28KXK@1|root,2ZADH@2|Bacteria,1V79T@1239|Firmicutes,24K1T@186801|Clostridia,3WJWA@541000|Ruminococcaceae	186801|Clostridia	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
BIFPGKOA_00893	657322.FPR_12340	1.06e-44	153.0	COG4607@1|root,COG4607@2|Bacteria,1UXCZ@1239|Firmicutes,2490M@186801|Clostridia	186801|Clostridia	P	periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
BIFPGKOA_00894	657322.FPR_14900	7.59e-110	325.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WGGB@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
BIFPGKOA_00895	657322.FPR_14910	7.17e-109	313.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,3WJ8D@541000|Ruminococcaceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
BIFPGKOA_00896	657322.FPR_14920	2.25e-238	656.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3WIKJ@541000|Ruminococcaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
BIFPGKOA_00897	657322.FPR_14930	0.0	1001.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3WIB4@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
BIFPGKOA_00898	657322.FPR_14940	4.77e-216	595.0	COG0152@1|root,COG0152@2|Bacteria,1VTBC@1239|Firmicutes,24ZTC@186801|Clostridia,3WH16@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
BIFPGKOA_00899	657322.FPR_14950	2.12e-112	322.0	COG1846@1|root,COG1846@2|Bacteria,1VA2S@1239|Firmicutes,25CPK@186801|Clostridia,3WM6Y@541000|Ruminococcaceae	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
BIFPGKOA_00901	411483.FAEPRAA2165_00408	2.42e-98	298.0	COG1196@1|root,COG1196@2|Bacteria,1UQCD@1239|Firmicutes,24AY9@186801|Clostridia,3WSPG@541000|Ruminococcaceae	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
BIFPGKOA_00902	411483.FAEPRAA2165_00409	1.79e-33	115.0	2DT21@1|root,33IBB@2|Bacteria,1VK9V@1239|Firmicutes,24VHP@186801|Clostridia,3WMJN@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00903	411483.FAEPRAA2165_02541	4.55e-53	166.0	2CZEX@1|root,32T68@2|Bacteria,1VB18@1239|Firmicutes,24MZP@186801|Clostridia,3WPUQ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00905	657322.FPR_15930	1.69e-158	444.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia,3WHG7@541000|Ruminococcaceae	186801|Clostridia	M	sugar transferase	cpsE	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
BIFPGKOA_00906	657322.FPR_15920	0.0	1084.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3WG9S@541000|Ruminococcaceae	186801|Clostridia	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
BIFPGKOA_00907	657322.FPR_15910	1.31e-245	674.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3WGY4@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
BIFPGKOA_00908	657322.FPR_15900	3.63e-124	354.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,3WJ0F@541000|Ruminococcaceae	186801|Clostridia	E	Acetolactate synthase small	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
BIFPGKOA_00909	657322.FPR_15890	0.0	935.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3WHFZ@541000|Ruminococcaceae	186801|Clostridia	H	acetolactate synthase large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
BIFPGKOA_00910	657322.FPR_19840	2.18e-108	312.0	COG0454@1|root,COG0456@2|Bacteria,1V4FY@1239|Firmicutes,25E88@186801|Clostridia,3WJBZ@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
BIFPGKOA_00911	657322.FPR_19830	0.0	1332.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WG7A@541000|Ruminococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
BIFPGKOA_00912	657322.FPR_19820	2.32e-259	711.0	COG3274@1|root,COG3274@2|Bacteria,1V90B@1239|Firmicutes,24IC7@186801|Clostridia,3WRX3@541000|Ruminococcaceae	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
BIFPGKOA_00913	657322.FPR_19810	4.08e-247	678.0	COG0438@1|root,COG0438@2|Bacteria,1V74B@1239|Firmicutes,2517N@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
BIFPGKOA_00914	657322.FPR_19800	1.7e-175	488.0	COG1409@1|root,COG1409@2|Bacteria,1TPVN@1239|Firmicutes,24AB4@186801|Clostridia,3WSPY@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
BIFPGKOA_00916	657322.FPR_02150	1.16e-85	256.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,3WIFE@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
BIFPGKOA_00917	657322.FPR_02160	5.07e-282	770.0	COG2199@1|root,COG2199@2|Bacteria,1TSU4@1239|Firmicutes,251V9@186801|Clostridia,3WJ37@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
BIFPGKOA_00918	657322.FPR_02170	1.75e-275	753.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3WGI3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
BIFPGKOA_00919	657322.FPR_02180	6.34e-276	754.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3WGVK@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ribose-phosphate pyrophosphokinase family	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
BIFPGKOA_00921	748224.HMPREF9436_02837	1.51e-281	772.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,3WH00@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
BIFPGKOA_00922	657322.FPR_04850	4.94e-152	426.0	COG1670@1|root,COG1670@2|Bacteria,1V6E0@1239|Firmicutes,24G2M@186801|Clostridia,3WJ7K@541000|Ruminococcaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
BIFPGKOA_00923	657322.FPR_04840	0.0	1044.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,248XC@186801|Clostridia,3WIMY@541000|Ruminococcaceae	186801|Clostridia	H	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
BIFPGKOA_00924	565664.EFXG_02137	3.39e-61	205.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HCW0@91061|Bacilli,4B1HJ@81852|Enterococcaceae	91061|Bacilli	M	group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BIFPGKOA_00925	657322.FPR_04820	1.78e-309	850.0	COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,24917@186801|Clostridia,3WHMM@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
BIFPGKOA_00926	718252.FP2_19630	3.89e-210	581.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia,3WNC8@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
BIFPGKOA_00927	718252.FP2_19640	2.32e-144	407.0	COG0637@1|root,COG0637@2|Bacteria,1VA1U@1239|Firmicutes,25BC7@186801|Clostridia	186801|Clostridia	S	HAD hydrolase, family IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
BIFPGKOA_00928	718252.FP2_19650	1.9e-232	640.0	COG2222@1|root,COG2222@2|Bacteria,1TRTA@1239|Firmicutes,24BGB@186801|Clostridia,3WJ2A@541000|Ruminococcaceae	186801|Clostridia	M	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS
BIFPGKOA_00929	718252.FP2_19660	1.61e-188	525.0	COG3716@1|root,COG3716@2|Bacteria,1URUT@1239|Firmicutes,24FDG@186801|Clostridia,3WRQV@541000|Ruminococcaceae	186801|Clostridia	G	PTS system mannose/fructose/sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
BIFPGKOA_00930	718252.FP2_19670	4.9e-174	487.0	COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,24CV1@186801|Clostridia,3WK42@541000|Ruminococcaceae	186801|Clostridia	G	PTS system sorbose-specific iic component	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
BIFPGKOA_00931	718252.FP2_19680	2.6e-106	306.0	COG3444@1|root,COG3444@2|Bacteria,1V5BR@1239|Firmicutes,24PJ5@186801|Clostridia,3WMU1@541000|Ruminococcaceae	186801|Clostridia	G	PTS system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTSIIB_sorb
BIFPGKOA_00932	718252.FP2_19690	1.88e-79	238.0	COG2893@1|root,COG2893@2|Bacteria,1UXME@1239|Firmicutes,24IW3@186801|Clostridia	186801|Clostridia	G	PTS system fructose IIA component	-	-	2.7.1.191	ko:K02793,ko:K19506	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276,M00764	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.6.1.19	-	-	EIIA-man
BIFPGKOA_00933	718252.FP2_19700	3.51e-165	462.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,24N1N@186801|Clostridia,3WKSM@541000|Ruminococcaceae	186801|Clostridia	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	ko:K03710,ko:K10711	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
BIFPGKOA_00934	657322.FPR_12160	9.18e-227	636.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGVP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
BIFPGKOA_00935	657322.FPR_12150	7.06e-49	163.0	COG1826@1|root,COG1826@2|Bacteria,1VHQF@1239|Firmicutes,24QW5@186801|Clostridia	186801|Clostridia	U	mttA/Hcf106 family	-	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
BIFPGKOA_00936	657322.FPR_12140	9.81e-33	114.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03117,ko:K03425	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
BIFPGKOA_00937	748224.HMPREF9436_00295	5.51e-158	446.0	COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,24KCD@186801|Clostridia	186801|Clostridia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
BIFPGKOA_00938	657322.FPR_12120	0.0	1492.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WH1C@541000|Ruminococcaceae	186801|Clostridia	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP_1	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
BIFPGKOA_00939	657322.FPR_12110	1.21e-207	573.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24BXX@186801|Clostridia,3WJ88@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
BIFPGKOA_00940	657322.FPR_12100	2.45e-53	167.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia,3WKXC@541000|Ruminococcaceae	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
BIFPGKOA_00941	657322.FPR_01950	4.34e-146	429.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,3WGM7@541000|Ruminococcaceae	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
BIFPGKOA_00942	748224.HMPREF9436_01806	3.08e-217	605.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WIY7@541000|Ruminococcaceae	186801|Clostridia	J	Metallo-beta-lactamase domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
BIFPGKOA_00943	657322.FPR_15560	1.74e-154	434.0	COG1410@1|root,COG1410@2|Bacteria,1V7JJ@1239|Firmicutes,24AE1@186801|Clostridia,3WJ7R@541000|Ruminococcaceae	186801|Clostridia	E	Vitamin B12 dependent methionine synthase activation	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
BIFPGKOA_00944	748224.HMPREF9436_01804	0.0	1393.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3WH5Y@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
BIFPGKOA_00945	657322.FPR_01890	7.13e-276	754.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,3WGQB@541000|Ruminococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
BIFPGKOA_00946	657322.FPR_01900	7.3e-119	347.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,3WGD1@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
BIFPGKOA_00947	657322.FPR_09150	8.79e-260	713.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3WHXU@541000|Ruminococcaceae	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
BIFPGKOA_00948	657322.FPR_09160	1.47e-54	170.0	2E36Q@1|root,32Y6E@2|Bacteria,1VEZV@1239|Firmicutes,24MQP@186801|Clostridia,3WKJK@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF370)	-	-	-	-	-	-	-	-	-	-	-	-	DUF370
BIFPGKOA_00949	657322.FPR_09170	0.0	1315.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,3WGZ0@541000|Ruminococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
BIFPGKOA_00950	718252.FP2_20040	0.0	1609.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,3WGW0@541000|Ruminococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
BIFPGKOA_00951	657322.FPR_30120	0.0	923.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate carboxylase, C-terminal domain subunit K01960	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
BIFPGKOA_00952	657322.FPR_30130	1.66e-73	220.0	29NZE@1|root,309XJ@2|Bacteria	2|Bacteria	S	Helix-turn-helix of DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_4
BIFPGKOA_00953	657322.FPR_30140	2.91e-198	550.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3WGMS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
BIFPGKOA_00954	657322.FPR_30150	5.98e-55	172.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,3WJWB@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
BIFPGKOA_00955	657322.FPR_30160	3.48e-128	365.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,3WIUW@541000|Ruminococcaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
BIFPGKOA_00956	657322.FPR_30170	0.0	1465.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3WGTG@541000|Ruminococcaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
BIFPGKOA_00957	411483.FAEPRAA2165_01547	1.83e-124	354.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,3WJGJ@541000|Ruminococcaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
BIFPGKOA_00959	657322.FPR_08820	0.0	1083.0	COG0517@1|root,COG1227@1|root,COG4109@1|root,COG0517@2|Bacteria,COG1227@2|Bacteria,COG4109@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,3WGK7@541000|Ruminococcaceae	186801|Clostridia	C	CBS domain	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
BIFPGKOA_00960	748224.HMPREF9436_00164	1.52e-68	209.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,3WKMB@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
BIFPGKOA_00964	657322.FPR_20990	5.9e-152	427.0	COG3764@1|root,COG3764@2|Bacteria,1VBCZ@1239|Firmicutes,24M77@186801|Clostridia,3WK15@541000|Ruminococcaceae	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
BIFPGKOA_00965	657322.FPR_20980	1.53e-220	610.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia	186801|Clostridia	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
BIFPGKOA_00966	479433.Caci_8699	0.000116	48.5	COG1846@1|root,COG1846@2|Bacteria,2IPB7@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
BIFPGKOA_00967	657322.FPR_20960	0.0	1405.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3WGF7@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
BIFPGKOA_00968	657322.FPR_06170	1.33e-190	530.0	COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,24DHZ@186801|Clostridia,3WRQW@541000|Ruminococcaceae	186801|Clostridia	ET	Amino acid ABC transporter substrate-binding protein, PAAT family (TC 3.A.1.3.-)	-	-	-	ko:K02424	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
BIFPGKOA_00969	657322.FPR_06180	5.62e-183	509.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3WNRV@541000|Ruminococcaceae	186801|Clostridia	E	Amino acid ABC transporter ATP-binding protein, PAAT family	tcyN	-	-	ko:K10010,ko:K16960	ko02010,map02010	M00234,M00585	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.10,3.A.1.3.13,3.A.1.3.14	-	-	ABC_tran
BIFPGKOA_00970	657322.FPR_06190	9.26e-149	420.0	COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,24BX1@186801|Clostridia,3WPRR@541000|Ruminococcaceae	186801|Clostridia	P	amino acid ABC transporter	-	-	-	ko:K10009	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1
BIFPGKOA_00971	748224.HMPREF9436_02567	1.35e-206	578.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,3WGZG@541000|Ruminococcaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
BIFPGKOA_00972	657322.FPR_06210	6.68e-195	540.0	COG0770@1|root,COG0770@2|Bacteria,1V1NG@1239|Firmicutes,24GE1@186801|Clostridia,3WM3U@541000|Ruminococcaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
BIFPGKOA_00973	657322.FPR_06220	1.09e-293	802.0	COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,24AYI@186801|Clostridia,3WHYR@541000|Ruminococcaceae	186801|Clostridia	S	Major Facilitator	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
BIFPGKOA_00974	748224.HMPREF9436_00213	1.76e-51	162.0	COG1925@1|root,COG1925@2|Bacteria,1VYCG@1239|Firmicutes,251I2@186801|Clostridia,3WKJQ@541000|Ruminococcaceae	186801|Clostridia	G	phosphocarrier, HPr family	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
BIFPGKOA_00975	657322.FPR_18250	1.85e-134	383.0	2BB2P@1|root,324IU@2|Bacteria,1UQTN@1239|Firmicutes,257SI@186801|Clostridia,3WMSF@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4830)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4830
BIFPGKOA_00976	657322.FPR_18260	1.53e-284	784.0	COG3757@1|root,COG3757@2|Bacteria,1V4GP@1239|Firmicutes,24FYR@186801|Clostridia,3WIS8@541000|Ruminococcaceae	186801|Clostridia	M	hydrolase, family 25	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Glyco_hydro_25,SH3_3
BIFPGKOA_00977	657322.FPR_18270	1.76e-236	652.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,3WGJT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
BIFPGKOA_00979	657322.FPR_27860	5e-230	643.0	COG5492@1|root,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,3WPAR@541000|Ruminococcaceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
BIFPGKOA_00980	657322.FPR_27850	0.0	1175.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3WGUC@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
BIFPGKOA_00981	657322.FPR_27840	3.91e-118	339.0	2B6MH@1|root,31ZJY@2|Bacteria,1VA4Q@1239|Firmicutes,24T66@186801|Clostridia,3WRG6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00982	657322.FPR_27830	3.57e-202	560.0	28PVZ@1|root,2ZCGE@2|Bacteria,1UPNZ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_00983	657322.FPR_27820	5.78e-288	786.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,3WGN5@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
BIFPGKOA_00984	748224.HMPREF9436_00966	1.39e-12	64.7	COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,24MPT@186801|Clostridia,3WJUX@541000|Ruminococcaceae	186801|Clostridia	J	S1 RNA binding domain	yugI	-	-	ko:K07570,ko:K07571	-	-	-	-	ko00000	-	-	-	S1
BIFPGKOA_00985	657322.FPR_10920	0.0	911.0	COG4277@1|root,COG4277@2|Bacteria,1TRT2@1239|Firmicutes,247UD@186801|Clostridia,3WHFC@541000|Ruminococcaceae	186801|Clostridia	L	DNA modification repair radical SAM protein	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
BIFPGKOA_00986	657322.FPR_10910	9.88e-197	544.0	COG1573@1|root,COG1573@2|Bacteria,1UY78@1239|Firmicutes,24FDP@186801|Clostridia,3WIWM@541000|Ruminococcaceae	186801|Clostridia	L	DNA metabolism protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
BIFPGKOA_00987	657322.FPR_10760	4.85e-58	182.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	spiA	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	EntA_Immun,HTH_3,Peptidase_M78,Peptidase_S24
BIFPGKOA_00988	657322.FPR_10750	5.65e-116	331.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3WHRC@541000|Ruminococcaceae	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
BIFPGKOA_00989	657322.FPR_10740	0.0	951.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,3WGT3@541000|Ruminococcaceae	186801|Clostridia	S	Oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
BIFPGKOA_00990	657322.FPR_10730	3.33e-150	424.0	COG3247@1|root,COG3247@2|Bacteria,1VFKP@1239|Firmicutes,24RBX@186801|Clostridia,3WJCX@541000|Ruminococcaceae	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
BIFPGKOA_00991	748224.HMPREF9436_01990	1.4e-101	308.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3WHF6@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_00993	657322.FPR_21750	5.35e-290	791.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,3WI1M@541000|Ruminococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
BIFPGKOA_00994	657322.FPR_21760	7.98e-309	842.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,3WGW3@541000|Ruminococcaceae	186801|Clostridia	F	pyrimidine-nucleoside phosphorylase	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
BIFPGKOA_00995	657322.FPR_21770	0.0	879.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,3WGP4@541000|Ruminococcaceae	186801|Clostridia	P	K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
BIFPGKOA_00996	657322.FPR_30230	0.0	1136.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WGK8@541000|Ruminococcaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
BIFPGKOA_00997	657322.FPR_30220	1.19e-180	502.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,3WJ4X@541000|Ruminococcaceae	186801|Clostridia	T	serine threonine protein phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
BIFPGKOA_00998	657322.FPR_30210	1.66e-247	679.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3WGYF@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
BIFPGKOA_00999	657322.FPR_30200	9.78e-296	810.0	COG0144@1|root,COG0144@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,3WGKM@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
BIFPGKOA_01000	657322.FPR_30190	5.13e-215	594.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,3WGPQ@541000|Ruminococcaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
BIFPGKOA_01001	657322.FPR_20320	9.21e-209	576.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3WGGA@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
BIFPGKOA_01002	748224.HMPREF9436_00877	4.33e-44	146.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3WKU1@541000|Ruminococcaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
BIFPGKOA_01003	657322.FPR_20300	0.0	979.0	COG0441@1|root,COG0441@2|Bacteria,1UHT4@1239|Firmicutes,25E98@186801|Clostridia,3WHAG@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
BIFPGKOA_01004	657322.FPR_20290	1.49e-221	609.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,3WK1R@541000|Ruminococcaceae	186801|Clostridia	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
BIFPGKOA_01005	657322.FPR_20280	1.83e-230	638.0	COG5002@1|root,COG5002@2|Bacteria,1TS83@1239|Firmicutes,249CD@186801|Clostridia,3WHFA@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
BIFPGKOA_01006	657322.FPR_18610	2.78e-52	169.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3WJQD@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
BIFPGKOA_01008	657322.FPR_18590	1.17e-249	686.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24E1V@186801|Clostridia,3WPUU@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
BIFPGKOA_01009	657322.FPR_18580	2.48e-275	755.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia,3WJFN@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
BIFPGKOA_01010	657322.FPR_18570	8.82e-119	339.0	COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,24N5U@186801|Clostridia,3WPZP@541000|Ruminococcaceae	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1	ptbA	-	-	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1
BIFPGKOA_01011	657322.FPR_18560	2.58e-277	757.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,3WH26@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
BIFPGKOA_01012	657322.FPR_15880	3.48e-288	787.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,3WH9K@541000|Ruminococcaceae	186801|Clostridia	S	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
BIFPGKOA_01013	657322.FPR_15870	8.49e-79	234.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3WJG0@541000|Ruminococcaceae	186801|Clostridia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
BIFPGKOA_01014	657322.FPR_15860	3.88e-283	774.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WH1M@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
BIFPGKOA_01015	748224.HMPREF9436_01317	6.63e-83	258.0	COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,249DU@186801|Clostridia,3WKV2@541000|Ruminococcaceae	186801|Clostridia	S	Pfam:TPM	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
BIFPGKOA_01016	657322.FPR_15830	8.45e-162	455.0	295NP@1|root,2ZT02@2|Bacteria,1W38K@1239|Firmicutes,2569B@186801|Clostridia,3WQQ1@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01017	748224.HMPREF9436_01315	8.58e-61	197.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the TelA family	-	-	-	-	-	-	-	-	-	-	-	-	TelA
BIFPGKOA_01018	657322.FPR_11790	2.69e-165	462.0	COG0745@1|root,COG0745@2|Bacteria,1TPN8@1239|Firmicutes,248UA@186801|Clostridia,3WGQR@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
BIFPGKOA_01019	657322.FPR_11780	7.62e-306	835.0	COG0457@1|root,COG0457@2|Bacteria,1VJFJ@1239|Firmicutes,25AZN@186801|Clostridia,3WS60@541000|Ruminococcaceae	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01020	411483.FAEPRAA2165_02817	1.94e-72	218.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,3WIRR@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
BIFPGKOA_01021	411483.FAEPRAA2165_02818	3.69e-222	613.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WGUM@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
BIFPGKOA_01022	748224.HMPREF9436_00341	1.25e-135	384.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
BIFPGKOA_01023	657322.FPR_11740	5.77e-79	235.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3WIYT@541000|Ruminococcaceae	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
BIFPGKOA_01024	657322.FPR_19860	0.0	1130.0	COG0188@1|root,COG0188@2|Bacteria,1TPPU@1239|Firmicutes,24CU3@186801|Clostridia,3WG8X@541000|Ruminococcaceae	186801|Clostridia	L	PFAM DNA gyrase topoisomerase IV, subunit A	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
BIFPGKOA_01025	657322.FPR_19870	9.65e-105	303.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,3WIDB@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
BIFPGKOA_01026	657322.FPR_19880	1.01e-191	533.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3WH7X@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
BIFPGKOA_01027	657322.FPR_19890	0.0	1377.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3WSRM@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
BIFPGKOA_01028	657322.FPR_06630	6.44e-118	346.0	COG3940@1|root,COG3940@2|Bacteria,1VAX9@1239|Firmicutes,24NY2@186801|Clostridia,3WKE6@541000|Ruminococcaceae	186801|Clostridia	G	Ricin-type beta-trefoil	-	-	-	-	-	-	-	-	-	-	-	-	RicinB_lectin_2
BIFPGKOA_01029	657322.FPR_06620	4.68e-315	860.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGNN@541000|Ruminococcaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_01031	657322.FPR_06600	1.9e-215	597.0	COG0226@1|root,COG0226@2|Bacteria,1VT8I@1239|Firmicutes,24IAW@186801|Clostridia,3WJDA@541000|Ruminococcaceae	186801|Clostridia	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
BIFPGKOA_01032	657322.FPR_09390	1.31e-270	739.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia,3WH61@541000|Ruminococcaceae	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
BIFPGKOA_01033	657322.FPR_09380	0.0	2323.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,3WGTT@541000|Ruminococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
BIFPGKOA_01034	657322.FPR_15680	8.13e-85	251.0	COG1433@1|root,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia,3WK5J@541000|Ruminococcaceae	186801|Clostridia	L	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
BIFPGKOA_01035	657322.FPR_15690	4.65e-185	514.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia,3WIT8@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
BIFPGKOA_01036	657322.FPR_15700	1.25e-209	580.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3WI8A@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BIFPGKOA_01037	657322.FPR_15710	0.0	878.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3WGUF@541000|Ruminococcaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
BIFPGKOA_01038	748224.HMPREF9436_02894	2.79e-206	573.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WG83@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
BIFPGKOA_01039	657322.FPR_16880	4.58e-216	596.0	COG1266@1|root,COG1266@2|Bacteria,1V416@1239|Firmicutes,24MKP@186801|Clostridia,3WMQU@541000|Ruminococcaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
BIFPGKOA_01040	657322.FPR_16870	5.4e-63	193.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,3WJX0@541000|Ruminococcaceae	186801|Clostridia	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
BIFPGKOA_01041	657322.FPR_16860	1.96e-145	410.0	COG0789@1|root,COG0789@2|Bacteria,1V53F@1239|Firmicutes,24IQ8@186801|Clostridia,3WKBG@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
BIFPGKOA_01042	657322.FPR_16850	1.59e-288	787.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,3WGD9@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
BIFPGKOA_01043	657322.FPR_16840	5.07e-62	190.0	COG0776@1|root,COG0776@2|Bacteria,1VZ6B@1239|Firmicutes,253S5@186801|Clostridia,3WQ7M@541000|Ruminococcaceae	186801|Clostridia	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
BIFPGKOA_01044	657322.FPR_16830	0.0	900.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,3WG9X@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
BIFPGKOA_01045	657322.FPR_29990	1.72e-236	654.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,3WHZ1@541000|Ruminococcaceae	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
BIFPGKOA_01046	657322.FPR_29980	5.62e-185	515.0	2F8HG@1|root,340WA@2|Bacteria,1VXQT@1239|Firmicutes,2529I@186801|Clostridia,3WPPF@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01047	657322.FPR_29970	3.17e-163	456.0	COG0125@1|root,COG0125@2|Bacteria,1V2D5@1239|Firmicutes,25CJJ@186801|Clostridia,3WIE4@541000|Ruminococcaceae	186801|Clostridia	F	thymidylate kinase	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
BIFPGKOA_01048	657322.FPR_29960	5.21e-180	501.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,249DJ@186801|Clostridia,3WGNR@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
BIFPGKOA_01049	657322.FPR_29950	0.0	1142.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WGKX@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
BIFPGKOA_01050	748224.HMPREF9436_01275	3.18e-181	513.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WHBC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
BIFPGKOA_01051	657322.FPR_29890	1.97e-170	476.0	COG3279@1|root,COG3279@2|Bacteria,1UYHU@1239|Firmicutes,24CBK@186801|Clostridia,3WRIR@541000|Ruminococcaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
BIFPGKOA_01052	657322.FPR_29900	2.29e-292	800.0	COG3290@1|root,COG3290@2|Bacteria,1UZ59@1239|Firmicutes,24A0V@186801|Clostridia,3WMIF@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
BIFPGKOA_01053	657322.FPR_29910	4.43e-100	290.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia,3WIXA@541000|Ruminococcaceae	186801|Clostridia	F	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
BIFPGKOA_01054	657322.FPR_29920	2.2e-224	618.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WG83@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
BIFPGKOA_01055	657322.FPR_29930	7.13e-130	371.0	COG2188@1|root,COG2188@2|Bacteria,1TQQQ@1239|Firmicutes,24C86@186801|Clostridia,3WJ26@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
BIFPGKOA_01056	657322.FPR_16100	1.56e-216	606.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia,3WHCF@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
BIFPGKOA_01057	657322.FPR_20520	4.64e-106	306.0	COG2731@1|root,COG2731@2|Bacteria,1VFU3@1239|Firmicutes,24JDR@186801|Clostridia,3WQG1@541000|Ruminococcaceae	186801|Clostridia	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
BIFPGKOA_01059	657322.FPR_20540	1.12e-207	581.0	COG3290@1|root,COG3290@2|Bacteria,1VC62@1239|Firmicutes,25E8N@186801|Clostridia,3WIB6@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
BIFPGKOA_01060	657322.FPR_20560	9.37e-169	471.0	COG3279@1|root,COG3279@2|Bacteria,1VEBW@1239|Firmicutes,24NE6@186801|Clostridia,3WM2U@541000|Ruminococcaceae	186801|Clostridia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
BIFPGKOA_01061	657322.FPR_16450	0.0	1030.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae	186801|Clostridia	J	translation elongation	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
BIFPGKOA_01062	657322.FPR_16460	0.0	1079.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,3WHGT@541000|Ruminococcaceae	186801|Clostridia	E	asparagine synthase (glutamine-hydrolyzing)	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7,NAD_synthase
BIFPGKOA_01063	657322.FPR_16470	8.3e-115	328.0	COG0735@1|root,COG0735@2|Bacteria,1V970@1239|Firmicutes,24QK7@186801|Clostridia,3WJUF@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
BIFPGKOA_01064	657322.FPR_16480	3.16e-152	428.0	COG1802@1|root,COG1802@2|Bacteria,1V5DF@1239|Firmicutes,24HJU@186801|Clostridia,3WRUX@541000|Ruminococcaceae	186801|Clostridia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
BIFPGKOA_01065	748224.HMPREF9436_02459	2.65e-20	87.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3WHK4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
BIFPGKOA_01066	657322.FPR_29250	4.88e-266	732.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
BIFPGKOA_01067	657322.FPR_29240	1.75e-175	492.0	COG0614@1|root,COG4822@1|root,COG0614@2|Bacteria,COG4822@2|Bacteria,1UK9K@1239|Firmicutes,25FRK@186801|Clostridia,3WJHV@541000|Ruminococcaceae	186801|Clostridia	HP	small periplasmic lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01068	657322.FPR_29230	7.46e-259	711.0	COG0614@1|root,COG0614@2|Bacteria,1TQ4U@1239|Firmicutes,249I2@186801|Clostridia,3WHGS@541000|Ruminococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
BIFPGKOA_01069	657322.FPR_29220	8.1e-219	606.0	COG0609@1|root,COG0609@2|Bacteria,1TQXW@1239|Firmicutes,249TJ@186801|Clostridia,3WI1U@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
BIFPGKOA_01070	657322.FPR_26310	1.57e-95	280.0	COG0711@1|root,COG0711@2|Bacteria,1VEI8@1239|Firmicutes	1239|Firmicutes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
BIFPGKOA_01071	748224.HMPREF9436_02445	8.95e-38	127.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3WKSD@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
BIFPGKOA_01072	657322.FPR_26290	1.37e-150	424.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,3WIAV@541000|Ruminococcaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
BIFPGKOA_01073	657322.FPR_26270	7.77e-103	298.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,3WK7E@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
BIFPGKOA_01077	657322.FPR_08820	0.0	1085.0	COG0517@1|root,COG1227@1|root,COG4109@1|root,COG0517@2|Bacteria,COG1227@2|Bacteria,COG4109@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,3WGK7@541000|Ruminococcaceae	186801|Clostridia	C	CBS domain	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
BIFPGKOA_01078	748224.HMPREF9436_00164	1.02e-66	205.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,3WKMB@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
BIFPGKOA_01082	657322.FPR_05480	2.41e-222	616.0	COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia,3WHWJ@541000|Ruminococcaceae	186801|Clostridia	P	Menaquinone biosynthesis	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,Phosphonate-bd,VitK2_biosynth
BIFPGKOA_01083	657322.FPR_05490	1.48e-149	422.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WKCU@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
BIFPGKOA_01084	657322.FPR_05500	9.09e-235	645.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,3WHGJ@541000|Ruminococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BIFPGKOA_01085	657322.FPR_05510	7.91e-141	397.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,3WIF0@541000|Ruminococcaceae	186801|Clostridia	S	Flavin reductase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
BIFPGKOA_01086	657322.FPR_05520	7.7e-111	320.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,3WK3X@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
BIFPGKOA_01087	657322.FPR_05530	5.49e-156	437.0	COG0546@1|root,COG0546@2|Bacteria,1V7EI@1239|Firmicutes,24K0E@186801|Clostridia,3WPBF@541000|Ruminococcaceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
BIFPGKOA_01088	657322.FPR_10020	0.0	1065.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3WGN6@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
BIFPGKOA_01089	657322.FPR_10010	5.55e-194	537.0	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	ytrP	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GAF_2,GAF_3,GGDEF,HAMP
BIFPGKOA_01090	657322.FPR_10000	7.62e-97	282.0	2BRQ4@1|root,32KPS@2|Bacteria,1V8GJ@1239|Firmicutes,24JFQ@186801|Clostridia,3WKHT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01091	657322.FPR_09990	6.87e-229	629.0	COG1208@1|root,COG1208@2|Bacteria,1UIRX@1239|Firmicutes,25EQU@186801|Clostridia,3WHF0@541000|Ruminococcaceae	186801|Clostridia	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
BIFPGKOA_01092	657322.FPR_09980	3.53e-115	329.0	COG1670@1|root,COG1670@2|Bacteria,1UHY0@1239|Firmicutes,25EFE@186801|Clostridia,3WJW3@541000|Ruminococcaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BIFPGKOA_01093	657322.FPR_27490	2.55e-109	325.0	COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae	186801|Clostridia	G	Carbohydrate ABC transporter	-	-	-	ko:K10200	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
BIFPGKOA_01094	657322.FPR_27500	1.24e-200	556.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WI95@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10201	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
BIFPGKOA_01095	657322.FPR_27510	9.1e-205	567.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3WHFG@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10202	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
BIFPGKOA_01096	748224.HMPREF9436_03160	1.61e-32	113.0	2E6GH@1|root,3313R@2|Bacteria,1VJ41@1239|Firmicutes,24S7U@186801|Clostridia,3WMQ0@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01097	748224.HMPREF9436_03161	0.0	1501.0	COG5426@1|root,COG5426@2|Bacteria,1TPH0@1239|Firmicutes,24892@186801|Clostridia,3WHG2@541000|Ruminococcaceae	186801|Clostridia	S	Lacto-N-biose phosphorylase C-terminal domain	gnpA	GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704	2.4.1.211	ko:K15533	-	-	-	-	ko00000,ko01000	-	-	-	LBP_C,LBP_M,Lact_bio_phlase
BIFPGKOA_01098	657322.FPR_11960	4.34e-201	557.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,3WRI5@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
BIFPGKOA_01099	657322.FPR_11970	1.14e-83	247.0	COG1266@1|root,COG1266@2|Bacteria,1VKW2@1239|Firmicutes,24QJG@186801|Clostridia,3WM89@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
BIFPGKOA_01100	657322.FPR_11980	3.77e-118	337.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,3WJHQ@541000|Ruminococcaceae	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
BIFPGKOA_01101	748224.HMPREF9436_00309	8.2e-151	433.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia,3WIP8@541000|Ruminococcaceae	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	fabG5	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
BIFPGKOA_01102	657322.FPR_12000	3.79e-307	840.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WGMV@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
BIFPGKOA_01103	657322.FPR_02290	0.0	1012.0	COG1783@1|root,COG1783@2|Bacteria,1TT85@1239|Firmicutes,24ETQ@186801|Clostridia,3WPQU@541000|Ruminococcaceae	186801|Clostridia	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
BIFPGKOA_01105	657322.FPR_02270	1.61e-231	639.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,3WJGA@541000|Ruminococcaceae	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
BIFPGKOA_01107	748224.HMPREF9436_00012	9.72e-279	773.0	COG1418@1|root,COG3599@1|root,COG1418@2|Bacteria,COG3599@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,3WGE5@541000|Ruminococcaceae	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
BIFPGKOA_01109	657322.FPR_09800	3.77e-272	748.0	COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,25CGY@186801|Clostridia,3WHQY@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
BIFPGKOA_01110	748224.HMPREF9436_00471	1.47e-98	288.0	2BDCF@1|root,32717@2|Bacteria,1USX3@1239|Firmicutes,25040@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01111	657322.FPR_20630	9.29e-132	374.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24JF9@186801|Clostridia,3WJRT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
BIFPGKOA_01113	657322.FPR_20610	1.2e-303	826.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia,3WGYP@541000|Ruminococcaceae	186801|Clostridia	E	carboxynorspermidine decarboxylase	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
BIFPGKOA_01114	657322.FPR_20600	6.5e-307	836.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,3WGMN@541000|Ruminococcaceae	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
BIFPGKOA_01115	657322.FPR_20590	1.87e-214	591.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,2493V@186801|Clostridia,3WHCY@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
BIFPGKOA_01116	411483.FAEPRAA2165_01731	1.21e-54	177.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,3WGDX@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
BIFPGKOA_01117	657322.FPR_29640	2.88e-162	457.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,24BAQ@186801|Clostridia,3WK59@541000|Ruminococcaceae	186801|Clostridia	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,Dockerin_1
BIFPGKOA_01118	748224.HMPREF9436_00983	4.27e-130	371.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,3WIHN@541000|Ruminococcaceae	186801|Clostridia	S	YigZ family	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
BIFPGKOA_01119	657322.FPR_29660	5.74e-241	662.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia,3WG8N@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
BIFPGKOA_01120	657322.FPR_29670	0.0	1152.0	COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3WGFW@541000|Ruminococcaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
BIFPGKOA_01121	657322.FPR_31450	1.58e-131	380.0	COG3599@1|root,COG3599@2|Bacteria,1VGCY@1239|Firmicutes,24TVY@186801|Clostridia,3WM0J@541000|Ruminococcaceae	186801|Clostridia	D	DivIVA domain protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
BIFPGKOA_01122	657322.FPR_31460	1.91e-193	536.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,3WJ3J@541000|Ruminococcaceae	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
BIFPGKOA_01123	657322.FPR_31470	3.29e-104	301.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,3WJJD@541000|Ruminococcaceae	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
BIFPGKOA_01124	657322.FPR_31480	2e-301	823.0	COG0845@1|root,COG0845@2|Bacteria,1V9GB@1239|Firmicutes,24HX2@186801|Clostridia,3WJMC@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01125	748224.HMPREF9436_01474	6.98e-179	503.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3WGGD@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
BIFPGKOA_01126	411483.FAEPRAA2165_02407	8.9e-32	122.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,3WHC5@541000|Ruminococcaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
BIFPGKOA_01127	411483.FAEPRAA2165_03052	5.47e-159	450.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,24A3I@186801|Clostridia,3WH9A@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
BIFPGKOA_01132	657322.FPR_01410	7.24e-147	413.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3WM48@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_3,HTH_31,Peptidase_S24
BIFPGKOA_01133	411489.CLOL250_01915	1.18e-23	91.7	2DNMA@1|root,32Y3J@2|Bacteria,1VJCJ@1239|Firmicutes,24RI7@186801|Clostridia,36Q0E@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01134	657322.FPR_01390	3.86e-173	482.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia,3WH52@541000|Ruminococcaceae	186801|Clostridia	S	Methyltransferase, YaeB family	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
BIFPGKOA_01135	657322.FPR_01380	1.01e-199	554.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,249AX@186801|Clostridia,3WJR3@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BIFPGKOA_01136	657322.FPR_14920	2.11e-40	142.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3WIKJ@541000|Ruminococcaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
BIFPGKOA_01138	657322.FPR_19770	1e-306	838.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WH49@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_01139	657322.FPR_19750	2.25e-245	676.0	COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,25CCK@186801|Clostridia,3WN27@541000|Ruminococcaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
BIFPGKOA_01140	411467.BACCAP_04767	5.11e-65	213.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,2698M@186813|unclassified Clostridiales	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BIFPGKOA_01141	742735.HMPREF9467_04293	2.94e-172	491.0	COG2391@1|root,COG2391@2|Bacteria,1TPWG@1239|Firmicutes,249KU@186801|Clostridia,21XFT@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
BIFPGKOA_01142	469378.Ccur_00550	1.43e-07	50.8	COG0425@1|root,COG0425@2|Bacteria,2HVHX@201174|Actinobacteria,4CWVI@84998|Coriobacteriia	84998|Coriobacteriia	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
BIFPGKOA_01143	718252.FP2_17640	9.8e-24	92.8	COG2033@1|root,COG2033@2|Bacteria,1VA34@1239|Firmicutes,24J9I@186801|Clostridia,3WJTY@541000|Ruminococcaceae	186801|Clostridia	C	Superoxide reductase	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
BIFPGKOA_01144	748224.HMPREF9436_02848	1.33e-38	129.0	2DP0F@1|root,32TXN@2|Bacteria,1UHKP@1239|Firmicutes,25E1U@186801|Clostridia,3WPV8@541000|Ruminococcaceae	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
BIFPGKOA_01145	657322.FPR_19030	2.07e-300	820.0	COG1192@1|root,COG4227@1|root,COG1192@2|Bacteria,COG4227@2|Bacteria,1UM3K@1239|Firmicutes,25G9Q@186801|Clostridia,3WSTD@541000|Ruminococcaceae	186801|Clostridia	DL	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	YodL
BIFPGKOA_01146	748224.HMPREF9436_03136	2.56e-54	170.0	COG0550@1|root,COG0550@2|Bacteria	2|Bacteria	L	DNA topoisomerase type I activity	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
BIFPGKOA_01147	657322.FPR_21330	3.96e-26	105.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3WI33@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM
BIFPGKOA_01148	657322.FPR_21340	0.0	1079.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1V4RJ@1239|Firmicutes,24IFN@186801|Clostridia,3WGT2@541000|Ruminococcaceae	186801|Clostridia	KLT	PASTA domain protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
BIFPGKOA_01149	657322.FPR_21350	0.0	1013.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,3WGBX@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
BIFPGKOA_01150	657322.FPR_21360	2.23e-300	860.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,3WHE2@541000|Ruminococcaceae	186801|Clostridia	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
BIFPGKOA_01151	657322.FPR_01310	8.9e-82	251.0	COG2199@1|root,COG2199@2|Bacteria,1TSU4@1239|Firmicutes,24DMY@186801|Clostridia,3WPF4@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
BIFPGKOA_01152	748224.HMPREF9436_02262	3.28e-47	158.0	2ES3K@1|root,33JNI@2|Bacteria,1VKAS@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01153	657322.FPR_01330	1.02e-121	347.0	COG0671@1|root,COG0671@2|Bacteria,1V7XD@1239|Firmicutes,25BF5@186801|Clostridia,3WS6D@541000|Ruminococcaceae	186801|Clostridia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
BIFPGKOA_01154	657322.FPR_01340	1.02e-232	640.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3WGC8@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	scrK	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
BIFPGKOA_01155	657322.FPR_01350	4.69e-298	815.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia,3WH7U@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_01156	748224.HMPREF9436_01798	1.78e-166	469.0	COG2207@1|root,COG2207@2|Bacteria,1VEKW@1239|Firmicutes,24SZV@186801|Clostridia,3WM13@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
BIFPGKOA_01157	657322.FPR_05270	6.35e-136	391.0	COG3842@1|root,COG3842@2|Bacteria,1TQ18@1239|Firmicutes,24AEK@186801|Clostridia,3WGIR@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
BIFPGKOA_01158	657322.FPR_05260	2.24e-81	240.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia	186801|Clostridia	S	protein with conserved CXXC pairs	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
BIFPGKOA_01159	657322.FPR_05250	1.34e-298	815.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,3WHBX@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
BIFPGKOA_01160	657322.FPR_05240	0.0	939.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,3WH8P@541000|Ruminococcaceae	186801|Clostridia	C	FAD dependent oxidoreductase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
BIFPGKOA_01161	657322.FPR_05230	2.26e-123	352.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,24HDM@186801|Clostridia,3WPST@541000|Ruminococcaceae	186801|Clostridia	K	Glycerol-3-phosphate responsive antiterminator	glpP	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
BIFPGKOA_01162	657322.FPR_05220	1.08e-63	204.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,3WIXP@541000|Ruminococcaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
BIFPGKOA_01163	657322.FPR_18390	1.04e-303	831.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGER@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
BIFPGKOA_01164	657322.FPR_18380	5.49e-149	419.0	COG0461@1|root,COG0461@2|Bacteria,1V23H@1239|Firmicutes,24FTS@186801|Clostridia,3WIVV@541000|Ruminococcaceae	186801|Clostridia	F	Orotate phosphoribosyltransferase	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
BIFPGKOA_01165	657322.FPR_18370	8.52e-208	573.0	COG4286@1|root,COG4286@2|Bacteria,1V2PW@1239|Firmicutes,248SR@186801|Clostridia,3WJFD@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterised protein family (UPF0160)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0160
BIFPGKOA_01166	657322.FPR_18360	3.49e-63	193.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,3WKVK@541000|Ruminococcaceae	186801|Clostridia	L	GIY-YIG catalytic domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
BIFPGKOA_01168	657322.FPR_26190	0.0	1305.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3WGEI@541000|Ruminococcaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
BIFPGKOA_01169	657322.FPR_26200	1.69e-231	637.0	COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,24B85@186801|Clostridia,3WIK6@541000|Ruminococcaceae	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
BIFPGKOA_01170	657322.FPR_26210	3.18e-196	543.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3WGAW@541000|Ruminococcaceae	186801|Clostridia	L	Hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
BIFPGKOA_01171	657322.FPR_26220	6.59e-52	163.0	2ED43@1|root,3370V@2|Bacteria,1VGAD@1239|Firmicutes,24RZU@186801|Clostridia,3WM6K@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01173	411483.FAEPRAA2165_01721	2.9e-208	577.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,3WIGP@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
BIFPGKOA_01174	411483.FAEPRAA2165_01720	2.19e-273	746.0	COG2334@1|root,COG2334@2|Bacteria,1VRV5@1239|Firmicutes,25EGP@186801|Clostridia,3WHGG@541000|Ruminococcaceae	186801|Clostridia	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
BIFPGKOA_01176	411483.FAEPRAA2165_01718	1.96e-146	413.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3WJFE@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
BIFPGKOA_01177	748224.HMPREF9436_02532	1.12e-44	146.0	2BACE@1|root,323SU@2|Bacteria,1UH7E@1239|Firmicutes,257YA@186801|Clostridia,3WKG9@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01178	411483.FAEPRAA2165_02932	6.09e-128	367.0	COG2129@1|root,COG2129@2|Bacteria,1V0W0@1239|Firmicutes,24A73@186801|Clostridia,3WJ04@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
BIFPGKOA_01179	657322.FPR_02410	0.0	1276.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia,3WSBH@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
BIFPGKOA_01180	748224.HMPREF9436_02535	8.96e-134	379.0	COG4333@1|root,COG4333@2|Bacteria,1V8CT@1239|Firmicutes,24K6U@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1643)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1643
BIFPGKOA_01181	718252.FP2_29280	9.73e-72	221.0	COG0671@1|root,COG0671@2|Bacteria,1VB2R@1239|Firmicutes,24MQ9@186801|Clostridia,3WMS0@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
BIFPGKOA_01182	657322.FPR_14520	5.64e-296	809.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WGDS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
BIFPGKOA_01183	657322.FPR_14510	0.0	1640.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WH14@541000|Ruminococcaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
BIFPGKOA_01184	657322.FPR_25630	2.18e-202	563.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,3WGDH@541000|Ruminococcaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
BIFPGKOA_01185	657322.FPR_25620	9.56e-317	863.0	COG4905@1|root,COG4905@2|Bacteria,1TQUM@1239|Firmicutes,25CKD@186801|Clostridia,3WGXM@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
BIFPGKOA_01186	748224.HMPREF9436_02434	7.94e-271	741.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHER@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
BIFPGKOA_01189	657322.FPR_00430	2.73e-205	568.0	2DCDQ@1|root,2ZDSD@2|Bacteria,1V33B@1239|Firmicutes,25BJU@186801|Clostridia,3WMNK@541000|Ruminococcaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
BIFPGKOA_01190	748224.HMPREF9436_02140	3.39e-155	436.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,3WIJ0@541000|Ruminococcaceae	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
BIFPGKOA_01191	657322.FPR_00450	7.58e-217	599.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,3WGMA@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
BIFPGKOA_01192	657322.FPR_00460	4.13e-228	627.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3WHZJ@541000|Ruminococcaceae	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
BIFPGKOA_01193	657322.FPR_00470	6.32e-55	171.0	COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,24MN7@186801|Clostridia,3WM3Z@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, AbrB family	-	-	-	ko:K06284	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin
BIFPGKOA_01194	657322.FPR_00480	1.17e-104	313.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia,3WJ8B@541000|Ruminococcaceae	186801|Clostridia	P	Transporter, CPA2 family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
BIFPGKOA_01195	748224.HMPREF9436_02255	9.47e-94	273.0	COG0745@1|root,COG0745@2|Bacteria,1W5YR@1239|Firmicutes,257F8@186801|Clostridia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
BIFPGKOA_01196	748224.HMPREF9436_02256	9.74e-108	310.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,3WINK@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
BIFPGKOA_01197	748224.HMPREF9436_02257	1.32e-293	800.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,3WGA9@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
BIFPGKOA_01198	748224.HMPREF9436_02258	1.3e-140	398.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,3WIGR@541000|Ruminococcaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
BIFPGKOA_01199	748224.HMPREF9436_02259	1.29e-281	768.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,3WG7W@541000|Ruminococcaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
BIFPGKOA_01200	748224.HMPREF9436_03175	9.19e-76	232.0	COG1191@1|root,COG1191@2|Bacteria,1VZE1@1239|Firmicutes,25442@186801|Clostridia,3WQK3@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
BIFPGKOA_01201	657322.FPR_06730	8.1e-136	385.0	COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,24I8W@186801|Clostridia,3WIWX@541000|Ruminococcaceae	186801|Clostridia	L	Ribonuclease M5	rnmV	-	3.1.26.8	ko:K05985	-	-	-	-	ko00000,ko01000	-	-	-	DUF4093,Toprim,Toprim_4
BIFPGKOA_01202	657322.FPR_06720	1.34e-235	649.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,3WJ8A@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
BIFPGKOA_01203	657322.FPR_06710	0.0	1071.0	COG0658@1|root,COG0658@2|Bacteria,1VGSX@1239|Firmicutes,249H4@186801|Clostridia,3WKE7@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
BIFPGKOA_01204	657322.FPR_16540	8.76e-48	161.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,3WGDN@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
BIFPGKOA_01205	657322.FPR_16530	1.53e-138	391.0	COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,24FT8@186801|Clostridia,3WGMJ@541000|Ruminococcaceae	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase HD sub domain	yfbR	-	3.1.3.89	ko:K07023,ko:K08722	ko00240,ko01100,map00240,map01100	-	R01569,R01664,R01968,R02088,R02102,R10776	RC00017	ko00000,ko00001,ko01000	-	-	-	HD_2,HD_3
BIFPGKOA_01206	657322.FPR_16520	0.0	1598.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24C9R@186801|Clostridia,3WH8M@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
BIFPGKOA_01207	657322.FPR_10150	3.19e-185	530.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,3WGSN@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,PUD
BIFPGKOA_01208	657322.FPR_10140	1.8e-272	752.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3WH0E@541000|Ruminococcaceae	186801|Clostridia	O	Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
BIFPGKOA_01209	657322.FPR_10130	5.32e-208	575.0	COG0454@1|root,COG2263@1|root,COG0456@2|Bacteria,COG2263@2|Bacteria,1UK73@1239|Firmicutes,25FNT@186801|Clostridia,3WSP2@541000|Ruminococcaceae	186801|Clostridia	JK	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,rRNA_methylase
BIFPGKOA_01211	657322.FPR_13710	0.0	1011.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3WRQU@541000|Ruminococcaceae	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
BIFPGKOA_01212	748224.HMPREF9436_01770	1.53e-62	191.0	COG3668@1|root,COG3668@2|Bacteria,1VB4X@1239|Firmicutes,24QHR@186801|Clostridia,3WQQ2@541000|Ruminococcaceae	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
BIFPGKOA_01213	657322.FPR_13690	3.57e-61	187.0	COG2161@1|root,COG2161@2|Bacteria,1VJMQ@1239|Firmicutes,24RCK@186801|Clostridia,3WKUK@541000|Ruminococcaceae	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
BIFPGKOA_01214	657322.FPR_11000	2.49e-298	821.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia,3WHCF@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
BIFPGKOA_01215	657322.FPR_31510	0.0	1692.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WGM4@541000|Ruminococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
BIFPGKOA_01216	657322.FPR_31520	1.79e-92	270.0	COG3679@1|root,COG3679@2|Bacteria,1VDFJ@1239|Firmicutes,24MY6@186801|Clostridia,3WJJP@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0342 family	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
BIFPGKOA_01217	748224.HMPREF9436_01419	2.6e-162	464.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,3WGSQ@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
BIFPGKOA_01218	748224.HMPREF9436_01257	2.67e-311	855.0	COG0370@1|root,COG0370@2|Bacteria,1UK3W@1239|Firmicutes,25FIS@186801|Clostridia,3WSQ3@541000|Ruminococcaceae	186801|Clostridia	P	Stage IV sporulation protein A (spore_IV_A)	spoIVA	-	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
BIFPGKOA_01219	657322.FPR_28870	2.29e-125	357.0	COG3432@1|root,COG3432@2|Bacteria,1VDQ8@1239|Firmicutes,24R9Q@186801|Clostridia,3WK5T@541000|Ruminococcaceae	186801|Clostridia	K	Domain of unknown function (DUF4364)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
BIFPGKOA_01220	657322.FPR_28880	1.74e-222	613.0	COG0539@1|root,COG0539@2|Bacteria,1UV93@1239|Firmicutes,249P6@186801|Clostridia,3WH6M@541000|Ruminococcaceae	186801|Clostridia	J	S1 RNA binding domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
BIFPGKOA_01221	657322.FPR_28890	4.7e-39	129.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,3WKJ4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
BIFPGKOA_01222	657322.FPR_29800	2.35e-170	475.0	COG4947@1|root,COG4947@2|Bacteria,1TSKW@1239|Firmicutes,2494P@186801|Clostridia	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
BIFPGKOA_01223	657322.FPR_29790	4.99e-76	227.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,3WJZ3@541000|Ruminococcaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
BIFPGKOA_01224	657322.FPR_29780	0.0	1574.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3WGJD@541000|Ruminococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
BIFPGKOA_01225	657322.FPR_09820	0.0	1195.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3WGVM@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
BIFPGKOA_01226	657322.FPR_09990	2.4e-229	630.0	COG1208@1|root,COG1208@2|Bacteria,1UIRX@1239|Firmicutes,25EQU@186801|Clostridia,3WHF0@541000|Ruminococcaceae	186801|Clostridia	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
BIFPGKOA_01227	657322.FPR_10000	7.62e-97	282.0	2BRQ4@1|root,32KPS@2|Bacteria,1V8GJ@1239|Firmicutes,24JFQ@186801|Clostridia,3WKHT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01228	657322.FPR_15060	2.92e-32	118.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,3WGU5@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
BIFPGKOA_01230	657322.FPR_15040	6.04e-139	392.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3WIEP@541000|Ruminococcaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
BIFPGKOA_01233	657322.FPR_31050	2.63e-156	437.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,3WGC2@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
BIFPGKOA_01234	657322.FPR_31060	4.27e-60	186.0	COG2315@1|root,COG2315@2|Bacteria,1V79C@1239|Firmicutes,257W8@186801|Clostridia,3WK2N@541000|Ruminococcaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
BIFPGKOA_01235	657322.FPR_31070	2.6e-233	642.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3WH67@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
BIFPGKOA_01236	657322.FPR_31080	0.0	1089.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WGNQ@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
BIFPGKOA_01237	657322.FPR_29780	1.38e-16	78.2	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3WGJD@541000|Ruminococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
BIFPGKOA_01238	748224.HMPREF9436_01025	3.67e-131	372.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3WGYN@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
BIFPGKOA_01239	657322.FPR_29760	8.68e-311	848.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,3WGSM@541000|Ruminococcaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pyrP	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
BIFPGKOA_01240	657322.FPR_29750	2.67e-253	696.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24AZ4@186801|Clostridia,3WNAA@541000|Ruminococcaceae	186801|Clostridia	H	aminotransferase class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
BIFPGKOA_01243	657322.FPR_09400	1.06e-261	715.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,3WGSG@541000|Ruminococcaceae	186801|Clostridia	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
BIFPGKOA_01246	657322.FPR_16710	3.23e-254	700.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
BIFPGKOA_01247	657322.FPR_29820	3.6e-113	327.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,24K0D@186801|Clostridia,3WJN0@541000|Ruminococcaceae	186801|Clostridia	S	peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
BIFPGKOA_01248	748224.HMPREF9436_01282	1.38e-134	385.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,3WJ4D@541000|Ruminococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
BIFPGKOA_01249	657322.FPR_29840	9.36e-124	353.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,3WJD2@541000|Ruminococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
BIFPGKOA_01250	657322.FPR_29850	1.61e-145	413.0	2DPRU@1|root,3334J@2|Bacteria,1VGDR@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
BIFPGKOA_01251	657322.FPR_29860	2.97e-86	254.0	COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,24JJ5@186801|Clostridia,3WJU2@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YtfJ	ytfJ	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
BIFPGKOA_01252	657322.FPR_29870	3.66e-188	523.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,3WHAC@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
BIFPGKOA_01254	657322.FPR_05200	5.39e-187	521.0	COG1266@1|root,COG1266@2|Bacteria,1VCV8@1239|Firmicutes,24F20@186801|Clostridia,3WMR7@541000|Ruminococcaceae	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
BIFPGKOA_01255	411483.FAEPRAA2165_01842	7.38e-50	158.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3WK6U@541000|Ruminococcaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
BIFPGKOA_01256	657322.FPR_28140	3.16e-51	165.0	COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes,24IDK@186801|Clostridia,3WIF9@541000|Ruminococcaceae	186801|Clostridia	K	Domain of unknown function (DUF1836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
BIFPGKOA_01258	748224.HMPREF9436_01423	2.38e-109	315.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3WIZR@541000|Ruminococcaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
BIFPGKOA_01259	657322.FPR_28120	5.97e-138	390.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3WHNZ@541000|Ruminococcaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
BIFPGKOA_01260	657322.FPR_28110	4.97e-70	211.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3WJW1@541000|Ruminococcaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
BIFPGKOA_01261	657322.FPR_28100	8.14e-269	751.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3WGA1@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
BIFPGKOA_01262	657322.FPR_28170	3.3e-220	610.0	28JX7@1|root,2Z9MQ@2|Bacteria,1UZRY@1239|Firmicutes,24AWA@186801|Clostridia,3WPXC@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01263	657322.FPR_28160	0.0	1012.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3WGSV@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls1	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
BIFPGKOA_01264	411483.FAEPRAA2165_03436	9.24e-26	102.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia,3WI03@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
BIFPGKOA_01265	657322.FPR_25950	0.0	976.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3WH6T@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
BIFPGKOA_01266	657322.FPR_25940	2.84e-104	302.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3WITM@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
BIFPGKOA_01267	657322.FPR_25920	5.17e-95	278.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,3WIUH@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
BIFPGKOA_01268	1519439.JPJG01000051_gene756	8.6e-50	166.0	COG0454@1|root,COG0454@2|Bacteria,1V4TJ@1239|Firmicutes,24IID@186801|Clostridia	186801|Clostridia	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BIFPGKOA_01269	718252.FP2_17850	3.16e-242	669.0	COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,25CD7@186801|Clostridia,3WGPH@541000|Ruminococcaceae	186801|Clostridia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
BIFPGKOA_01270	411483.FAEPRAA2165_02224	1.87e-314	859.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WH3J@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
BIFPGKOA_01271	657322.FPR_26340	5.64e-90	276.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3WGVH@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
BIFPGKOA_01272	657322.FPR_26350	4.73e-88	259.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,3WJYM@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
BIFPGKOA_01273	657322.FPR_20130	2.8e-234	646.0	COG0330@1|root,COG0330@2|Bacteria,1TRN5@1239|Firmicutes,248UU@186801|Clostridia,3WI4C@541000|Ruminococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
BIFPGKOA_01274	748224.HMPREF9436_01096	6e-41	134.0	COG4877@1|root,COG4877@2|Bacteria,1VEY1@1239|Firmicutes,24MV0@186801|Clostridia,3WKKV@541000|Ruminococcaceae	186801|Clostridia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	ParD_like,RHH_5
BIFPGKOA_01275	657322.FPR_20160	4.04e-204	564.0	COG3947@1|root,COG3947@2|Bacteria,1URI4@1239|Firmicutes,24GP6@186801|Clostridia,3WJC3@541000|Ruminococcaceae	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
BIFPGKOA_01276	748224.HMPREF9436_00325	4.64e-183	520.0	COG0544@1|root,COG0544@2|Bacteria,1V3TE@1239|Firmicutes,24AAA@186801|Clostridia,3WNHD@541000|Ruminococcaceae	186801|Clostridia	O	peptidylprolyl isomerase	tig_1	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C
BIFPGKOA_01277	748224.HMPREF9436_00323	1.76e-278	761.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3WG9F@541000|Ruminococcaceae	186801|Clostridia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
BIFPGKOA_01278	657322.FPR_11890	1.92e-201	557.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3WH30@541000|Ruminococcaceae	186801|Clostridia	C	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
BIFPGKOA_01279	657322.FPR_07600	8.77e-43	156.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0834@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
BIFPGKOA_01280	657322.FPR_07600	2.53e-281	796.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0834@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
BIFPGKOA_01281	657322.FPR_07620	1.23e-47	154.0	COG1162@1|root,COG1162@2|Bacteria,1V272@1239|Firmicutes,24CIG@186801|Clostridia,3WQCD@541000|Ruminococcaceae	186801|Clostridia	S	RNHCP domain	-	-	-	-	-	-	-	-	-	-	-	-	RNHCP,RsgA_GTPase
BIFPGKOA_01282	657322.FPR_07630	1.24e-177	494.0	COG1246@1|root,COG1246@2|Bacteria,1TRN6@1239|Firmicutes,2484V@186801|Clostridia,3WGHV@541000|Ruminococcaceae	186801|Clostridia	E	YoaP-like	yoaP	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
BIFPGKOA_01283	657322.FPR_07640	9.36e-124	353.0	COG0454@1|root,COG0456@2|Bacteria,1VAZN@1239|Firmicutes,24FQG@186801|Clostridia	186801|Clostridia	K	Acetyltransferase GNAT family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_4
BIFPGKOA_01284	657322.FPR_07650	8.1e-35	125.0	COG0300@1|root,COG0300@2|Bacteria,1UHN7@1239|Firmicutes,25FVQ@186801|Clostridia	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BIFPGKOA_01285	657322.FPR_30060	0.0	1286.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia,3WSDQ@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
BIFPGKOA_01286	657322.FPR_30050	1.04e-64	197.0	COG1873@1|root,COG1873@2|Bacteria,1TUA5@1239|Firmicutes,259AT@186801|Clostridia,3WMB7@541000|Ruminococcaceae	186801|Clostridia	S	sporulation protein, YlmC YmxH family	-	-	-	-	-	-	-	-	-	-	-	-	PRC
BIFPGKOA_01287	657322.FPR_30040	3.08e-147	414.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia,3WKIQ@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
BIFPGKOA_01288	657322.FPR_30030	2.43e-34	117.0	291XB@1|root,2ZPGX@2|Bacteria,1W4VH@1239|Firmicutes,255C3@186801|Clostridia,3WQUH@541000|Ruminococcaceae	186801|Clostridia	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
BIFPGKOA_01289	657322.FPR_09700	5.96e-142	417.0	COG5263@1|root,COG5263@2|Bacteria,1V1J6@1239|Firmicutes,24G0Y@186801|Clostridia	186801|Clostridia	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01290	97138.C820_00139	3.36e-18	84.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia,36GJ7@31979|Clostridiaceae	186801|Clostridia	K	lacI family	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	LacI,Peripla_BP_3
BIFPGKOA_01291	657322.FPR_09720	2.58e-164	460.0	COG3279@1|root,COG3279@2|Bacteria,1UHWR@1239|Firmicutes,24G6Q@186801|Clostridia,3WJ5E@541000|Ruminococcaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
BIFPGKOA_01292	657322.FPR_09730	7.43e-295	806.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,2494S@186801|Clostridia,3WHWQ@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
BIFPGKOA_01293	657322.FPR_03770	2.82e-237	653.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,3WGC6@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
BIFPGKOA_01294	657322.FPR_03760	0.0	909.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,24971@186801|Clostridia,3WGA0@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
BIFPGKOA_01295	657322.FPR_03750	5.83e-206	585.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,3WGDZ@541000|Ruminococcaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
BIFPGKOA_01296	411483.FAEPRAA2165_00969	1.48e-35	131.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3WGBI@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
BIFPGKOA_01297	657322.FPR_25890	6.67e-261	714.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,3WIJZ@541000|Ruminococcaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
BIFPGKOA_01298	657322.FPR_25900	1.56e-93	273.0	2DSCR@1|root,33FK0@2|Bacteria,1VKCD@1239|Firmicutes,24XEQ@186801|Clostridia,3WQQW@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3783
BIFPGKOA_01299	748224.HMPREF9436_02427	6.97e-240	659.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,3WG9J@541000|Ruminococcaceae	186801|Clostridia	E	synthase	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
BIFPGKOA_01300	657322.FPR_13350	0.0	1076.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3WGSV@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
BIFPGKOA_01301	1280681.AUJZ01000001_gene1005	5.38e-91	285.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia,4BXS7@830|Butyrivibrio	186801|Clostridia	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
BIFPGKOA_01302	657322.FPR_07160	4.93e-148	417.0	2F7SW@1|root,34070@2|Bacteria,1VY8Y@1239|Firmicutes,2521C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01303	411483.FAEPRAA2165_02228	3.34e-137	388.0	28WZY@1|root,2ZIYW@2|Bacteria,1V2ER@1239|Firmicutes,24G8Y@186801|Clostridia,3WKW9@541000|Ruminococcaceae	186801|Clostridia	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
BIFPGKOA_01304	411483.FAEPRAA2165_02229	7.22e-163	455.0	28JYM@1|root,2Z9NU@2|Bacteria,1TT2X@1239|Firmicutes,24CUC@186801|Clostridia,3WNH8@541000|Ruminococcaceae	186801|Clostridia	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
BIFPGKOA_01305	411483.FAEPRAA2165_02230	6.8e-221	609.0	COG1893@1|root,COG1893@2|Bacteria,1V4R7@1239|Firmicutes,25BA6@186801|Clostridia,3WIX1@541000|Ruminococcaceae	186801|Clostridia	H	Ketopantoate reductase PanE/ApbA	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA
BIFPGKOA_01306	657322.FPR_16630	2.03e-79	240.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3WH4A@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
BIFPGKOA_01307	411483.FAEPRAA2165_01008	4.88e-112	322.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3WIH7@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
BIFPGKOA_01308	657322.FPR_16650	1.32e-57	181.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
BIFPGKOA_01309	657322.FPR_16660	2.09e-210	581.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,3WHU4@541000|Ruminococcaceae	186801|Clostridia	S	Phospholipase, patatin family	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
BIFPGKOA_01311	748224.HMPREF9436_01345	0.0	1809.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3WGS6@541000|Ruminococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
BIFPGKOA_01312	748224.HMPREF9436_01344	7.37e-35	131.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,3WGH5@541000|Ruminococcaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
BIFPGKOA_01313	657322.FPR_21250	1.17e-156	451.0	COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,247TG@186801|Clostridia,3WGE9@541000|Ruminococcaceae	186801|Clostridia	G	Mannitol dehydrogenase	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
BIFPGKOA_01314	657322.FPR_21260	6.65e-126	358.0	2EDD1@1|root,3379C@2|Bacteria,1W2ES@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01315	657322.FPR_21270	0.0	980.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia,3WHGB@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
BIFPGKOA_01316	657322.FPR_13840	9.33e-295	803.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3WGQU@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
BIFPGKOA_01317	657322.FPR_13850	4.61e-188	522.0	COG0037@1|root,COG0037@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,3WH40@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the TtcA family	ttcA2	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
BIFPGKOA_01319	411483.FAEPRAA2165_00419	2.22e-60	197.0	COG2199@1|root,COG2199@2|Bacteria,1TSU4@1239|Firmicutes,24DMY@186801|Clostridia,3WPF4@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
BIFPGKOA_01320	657322.FPR_10420	2.17e-161	453.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia,3WKKW@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
BIFPGKOA_01321	657322.FPR_10410	0.0	1196.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3WGPR@541000|Ruminococcaceae	186801|Clostridia	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
BIFPGKOA_01322	657322.FPR_21310	3.91e-232	642.0	COG1638@1|root,COG1638@2|Bacteria,1TSSW@1239|Firmicutes,24DW9@186801|Clostridia,3WRTX@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
BIFPGKOA_01323	748224.HMPREF9436_00103	1.43e-170	484.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24BWQ@186801|Clostridia	186801|Clostridia	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
BIFPGKOA_01324	657322.FPR_21280	3.64e-113	329.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24FGY@186801|Clostridia,3WRMJ@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
BIFPGKOA_01325	657322.FPR_01000	1.8e-70	218.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,3WIPP@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
BIFPGKOA_01326	411483.FAEPRAA2165_02799	2.69e-76	229.0	COG0346@1|root,COG0346@2|Bacteria,1V3G8@1239|Firmicutes,24GRD@186801|Clostridia	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BIFPGKOA_01327	657322.FPR_00980	1.28e-298	813.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,3WGXI@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
BIFPGKOA_01328	657322.FPR_00970	3.7e-285	778.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,3WH96@541000|Ruminococcaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
BIFPGKOA_01329	657322.FPR_29680	1.01e-99	298.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WGMV@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
BIFPGKOA_01331	657322.FPR_10050	6.15e-40	131.0	2EGE3@1|root,33A60@2|Bacteria	2|Bacteria	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01332	657322.FPR_10060	5.6e-210	586.0	COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia,3WIV4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
BIFPGKOA_01334	1133850.SHJG_8254	2.76e-08	63.5	COG1835@1|root,COG1835@2|Bacteria,2I91W@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	mdmB	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
BIFPGKOA_01335	657322.FPR_23710	3.27e-58	180.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3WJT1@541000|Ruminococcaceae	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
BIFPGKOA_01337	718252.FP2_08170	5.39e-96	288.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,3WJ2Q@541000|Ruminococcaceae	186801|Clostridia	T	LytTr DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
BIFPGKOA_01338	1007096.BAGW01000014_gene1154	5.05e-40	155.0	COG3290@1|root,COG3290@2|Bacteria,1V34R@1239|Firmicutes,25AZ0@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
BIFPGKOA_01339	657322.FPR_13720	5.7e-229	635.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WGRQ@541000|Ruminococcaceae	186801|Clostridia	C	pyridine nucleotide-disulfide oxidoreductase	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
BIFPGKOA_01340	657322.FPR_18170	2.36e-305	833.0	COG0739@1|root,COG0739@2|Bacteria,1V7QV@1239|Firmicutes,24M4A@186801|Clostridia,3WNIT@541000|Ruminococcaceae	186801|Clostridia	M	Peptidase, M23 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
BIFPGKOA_01341	657322.FPR_18160	1.11e-28	103.0	28ZEN@1|root,2ZM68@2|Bacteria,1W2T3@1239|Firmicutes,257D2@186801|Clostridia,3WRA6@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01342	748224.HMPREF9436_02018	4.72e-211	587.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,3WH2W@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
BIFPGKOA_01343	657322.FPR_18140	2.04e-53	179.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,3WGDY@541000|Ruminococcaceae	186801|Clostridia	J	asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
BIFPGKOA_01344	657322.FPR_30080	8.81e-73	226.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
BIFPGKOA_01345	748224.HMPREF9436_01003	8.04e-209	605.0	COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,25E4R@186801|Clostridia,3WS66@541000|Ruminococcaceae	186801|Clostridia	C	Membrane domain of glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
BIFPGKOA_01346	657322.FPR_14990	9.45e-163	469.0	COG3250@1|root,COG3250@2|Bacteria,1TQAM@1239|Firmicutes,248XS@186801|Clostridia,3WI0J@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
BIFPGKOA_01347	657322.FPR_15010	0.0	1127.0	COG0491@1|root,COG4099@1|root,COG0491@2|Bacteria,COG4099@2|Bacteria,1TRER@1239|Firmicutes,2492V@186801|Clostridia,3WMT7@541000|Ruminococcaceae	186801|Clostridia	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,BAAT_C,Peptidase_S9
BIFPGKOA_01348	657322.FPR_15020	2.18e-29	113.0	2DPZM@1|root,33447@2|Bacteria,1VKXN@1239|Firmicutes,25FPN@186801|Clostridia,3WMCE@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01349	657322.FPR_11860	1.84e-132	376.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,3WITZ@541000|Ruminococcaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
BIFPGKOA_01350	657322.FPR_11850	0.0	896.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,3WH46@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
BIFPGKOA_01351	657322.FPR_11840	4.51e-107	310.0	COG2137@1|root,COG2137@2|Bacteria,1VM9C@1239|Firmicutes	1239|Firmicutes	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
BIFPGKOA_01352	657322.FPR_11830	2.43e-101	303.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3WGST@541000|Ruminococcaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
BIFPGKOA_01353	657322.FPR_16500	1.73e-201	560.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3WGQG@541000|Ruminococcaceae	186801|Clostridia	P	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
BIFPGKOA_01354	657322.FPR_16490	1.27e-182	509.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3WHK4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
BIFPGKOA_01355	657322.FPR_16480	7.75e-153	429.0	COG1802@1|root,COG1802@2|Bacteria,1V5DF@1239|Firmicutes,24HJU@186801|Clostridia,3WRUX@541000|Ruminococcaceae	186801|Clostridia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
BIFPGKOA_01356	657322.FPR_14590	7.92e-141	399.0	COG1802@1|root,COG1802@2|Bacteria,1V3SB@1239|Firmicutes,24EKV@186801|Clostridia,3WM22@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
BIFPGKOA_01357	411483.FAEPRAA2165_01540	1.27e-149	422.0	2DB6M@1|root,2Z7HS@2|Bacteria,1U8V8@1239|Firmicutes,249IN@186801|Clostridia,3WHIR@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF2871
BIFPGKOA_01358	657322.FPR_14610	1.06e-128	365.0	COG1309@1|root,COG1309@2|Bacteria,1V7CM@1239|Firmicutes,24K3K@186801|Clostridia,3WMJU@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BIFPGKOA_01359	657322.FPR_14620	2.41e-59	188.0	2C176@1|root,2ZD1S@2|Bacteria,1W5ZC@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01361	657322.FPR_24220	2.91e-231	637.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3WH56@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
BIFPGKOA_01362	657322.FPR_24230	1.31e-140	397.0	COG0125@1|root,COG0125@2|Bacteria,1VI7E@1239|Firmicutes	1239|Firmicutes	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28,dNK
BIFPGKOA_01365	657322.FPR_20320	2.64e-208	575.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3WGGA@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
BIFPGKOA_01366	748224.HMPREF9436_00877	4.33e-44	146.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3WKU1@541000|Ruminococcaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
BIFPGKOA_01367	657322.FPR_01910	8.06e-96	279.0	COG3682@1|root,COG3682@2|Bacteria,1VQ59@1239|Firmicutes,24WQW@186801|Clostridia,3WMD3@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, BlaI MecI CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
BIFPGKOA_01368	657322.FPR_01920	0.0	905.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3WGKI@541000|Ruminococcaceae	186801|Clostridia	C	citrate synthase	gltA2	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
BIFPGKOA_01370	657322.FPR_18630	2.5e-164	459.0	COG1396@1|root,COG1396@2|Bacteria,1V2ZX@1239|Firmicutes,24EC9@186801|Clostridia,3WIEA@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
BIFPGKOA_01371	657322.FPR_18620	4.19e-63	200.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,zinc_ribbon_2
BIFPGKOA_01372	657322.FPR_05810	3.84e-161	451.0	COG3738@1|root,COG3738@2|Bacteria,1V2SQ@1239|Firmicutes,24F5T@186801|Clostridia,3WNEN@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
BIFPGKOA_01373	657322.FPR_05820	4.04e-207	572.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3WGNI@541000|Ruminococcaceae	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
BIFPGKOA_01374	657322.FPR_27830	2.51e-202	560.0	28PVZ@1|root,2ZCGE@2|Bacteria,1UPNZ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01375	657322.FPR_27820	1.73e-289	790.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,3WGN5@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
BIFPGKOA_01376	748224.HMPREF9436_00966	8.75e-66	205.0	COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,24MPT@186801|Clostridia,3WJUX@541000|Ruminococcaceae	186801|Clostridia	J	S1 RNA binding domain	yugI	-	-	ko:K07570,ko:K07571	-	-	-	-	ko00000	-	-	-	S1
BIFPGKOA_01377	411483.FAEPRAA2165_02204	8.65e-53	166.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,3WJU0@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
BIFPGKOA_01378	411483.FAEPRAA2165_02205	1.25e-64	197.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,3WJUU@541000|Ruminococcaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
BIFPGKOA_01379	657322.FPR_21120	5.19e-251	688.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,3WH7A@541000|Ruminococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
BIFPGKOA_01380	657322.FPR_21110	5.48e-77	241.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,3WGKT@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase M16 inactive domain	ymfH	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
BIFPGKOA_01381	657322.FPR_09180	3.31e-313	874.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,3WGW0@541000|Ruminococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
BIFPGKOA_01382	657322.FPR_09190	1.2e-125	358.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,3WJ0X@541000|Ruminococcaceae	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
BIFPGKOA_01383	411483.FAEPRAA2165_01400	7.02e-30	117.0	2E33N@1|root,32Y3S@2|Bacteria,1VFAP@1239|Firmicutes,24R1K@186801|Clostridia,3WMAX@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
BIFPGKOA_01385	657322.FPR_20380	7.16e-235	648.0	COG2755@1|root,COG2755@2|Bacteria,1V2MD@1239|Firmicutes,24FWG@186801|Clostridia,3WS5Y@541000|Ruminococcaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
BIFPGKOA_01386	657322.FPR_14570	3.46e-211	584.0	COG0561@1|root,COG0561@2|Bacteria,1U3W2@1239|Firmicutes,2486H@186801|Clostridia,3WJGV@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
BIFPGKOA_01387	657322.FPR_14580	2.25e-158	443.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,3WJUP@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
BIFPGKOA_01389	657322.FPR_18080	1.14e-71	216.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,3WK2T@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
BIFPGKOA_01390	657322.FPR_18070	1.01e-228	631.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,25EAS@186801|Clostridia,3WGIZ@541000|Ruminococcaceae	186801|Clostridia	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
BIFPGKOA_01391	657322.FPR_18060	5.75e-98	285.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,3WJNA@541000|Ruminococcaceae	186801|Clostridia	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
BIFPGKOA_01392	748224.HMPREF9436_00857	1.01e-268	760.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,3WGW6@541000|Ruminococcaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
BIFPGKOA_01393	657322.FPR_05000	0.0	885.0	COG3581@1|root,COG3581@2|Bacteria,1TRVV@1239|Firmicutes,24947@186801|Clostridia,3WH15@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
BIFPGKOA_01394	411483.FAEPRAA2165_00651	1.02e-38	143.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3WHZY@541000|Ruminococcaceae	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,SHOCT
BIFPGKOA_01396	411483.FAEPRAA2165_00652	4.97e-181	513.0	COG2888@1|root,COG2888@2|Bacteria,1UK70@1239|Firmicutes,25FNQ@186801|Clostridia,3WSPV@541000|Ruminococcaceae	186801|Clostridia	J	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01397	411483.FAEPRAA2165_00653	1.55e-80	250.0	COG1512@1|root,COG1512@2|Bacteria,1V2US@1239|Firmicutes,24MZW@186801|Clostridia	186801|Clostridia	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
BIFPGKOA_01398	411483.FAEPRAA2165_03175	1.83e-70	214.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia,3WIWV@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, AsnC family	Lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
BIFPGKOA_01399	748224.HMPREF9436_02375	9.94e-287	783.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WGAJ@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
BIFPGKOA_01400	657322.FPR_03620	8.42e-173	486.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,3WH6J@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
BIFPGKOA_01401	748224.HMPREF9436_02372	3.56e-40	133.0	COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes,24QKW@186801|Clostridia,3WKT4@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
BIFPGKOA_01402	657322.FPR_19850	0.0	1343.0	COG0187@1|root,COG0187@2|Bacteria,1TQ6U@1239|Firmicutes,249NI@186801|Clostridia,3WH8Y@541000|Ruminococcaceae	186801|Clostridia	L	DNA topoisomerase	-	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
BIFPGKOA_01403	657322.FPR_19690	1.56e-155	437.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,3WH3Z@541000|Ruminococcaceae	186801|Clostridia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
BIFPGKOA_01404	657322.FPR_19700	0.0	951.0	COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,248WW@186801|Clostridia	186801|Clostridia	E	amino acid	NPD5_3681	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
BIFPGKOA_01406	657322.FPR_05880	8.63e-186	517.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,3WGUI@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
BIFPGKOA_01407	657322.FPR_05890	6.18e-115	330.0	COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,24JF7@186801|Clostridia,3WJFT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	thiW	-	-	-	-	-	-	-	-	-	-	-	ThiW
BIFPGKOA_01408	657322.FPR_13420	1.75e-99	290.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24IT1@186801|Clostridia,3WS1Z@541000|Ruminococcaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
BIFPGKOA_01409	411483.FAEPRAA2165_00710	1.11e-55	174.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3WK2P@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
BIFPGKOA_01410	657322.FPR_13440	9.4e-177	492.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6A@186801|Clostridia,3WIKS@541000|Ruminococcaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
BIFPGKOA_01411	657322.FPR_13450	1.03e-111	321.0	2E0RM@1|root,335S7@2|Bacteria,1VJ0P@1239|Firmicutes,24T08@186801|Clostridia,3WMKS@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
BIFPGKOA_01412	411483.FAEPRAA2165_00713	2.35e-47	152.0	29GWS@1|root,303UH@2|Bacteria,1TV9P@1239|Firmicutes,25A3V@186801|Clostridia,3WR4T@541000|Ruminococcaceae	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
BIFPGKOA_01413	657322.FPR_13020	1.09e-48	162.0	COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,24A7U@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
BIFPGKOA_01415	411483.FAEPRAA2165_01076	9.2e-100	291.0	2DMMK@1|root,32SFZ@2|Bacteria,1VARW@1239|Firmicutes,24NN3@186801|Clostridia,3WPMY@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01416	657322.FPR_12990	4.38e-303	827.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3WGH0@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
BIFPGKOA_01417	657322.FPR_00520	5.49e-148	435.0	COG1327@1|root,COG1328@1|root,COG1327@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3WHPK@541000|Ruminococcaceae	186801|Clostridia	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
BIFPGKOA_01418	657322.FPR_00510	8.66e-140	394.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,3WIIU@541000|Ruminococcaceae	186801|Clostridia	C	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
BIFPGKOA_01419	657322.FPR_00500	0.0	875.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,3WHAU@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
BIFPGKOA_01420	411483.FAEPRAA2165_03173	4.73e-190	530.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,3WH6J@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
BIFPGKOA_01421	657322.FPR_03610	3.71e-280	766.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WGAJ@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
BIFPGKOA_01422	411483.FAEPRAA2165_03175	2.87e-83	247.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia,3WIWV@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, AsnC family	Lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
BIFPGKOA_01423	445975.COLSTE_01461	5.69e-40	134.0	2B2EU@1|root,31UZG@2|Bacteria,2HWDH@201174|Actinobacteria,4CYA6@84998|Coriobacteriia	84998|Coriobacteriia	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
BIFPGKOA_01424	445975.COLSTE_01462	5.21e-25	95.9	2DNVU@1|root,32ZE7@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
BIFPGKOA_01425	748224.HMPREF9436_01521	8.74e-236	649.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,3WGX7@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Phosphate acetyl butaryl transferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
BIFPGKOA_01426	657322.FPR_19920	1.86e-288	787.0	COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,2483N@186801|Clostridia,3WK0W@541000|Ruminococcaceae	186801|Clostridia	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
BIFPGKOA_01427	657322.FPR_06390	5.28e-191	533.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,3WIW1@541000|Ruminococcaceae	186801|Clostridia	P	NLPA lipoprotein	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
BIFPGKOA_01428	411483.FAEPRAA2165_03034	1.72e-208	580.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,3WGFP@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
BIFPGKOA_01429	657322.FPR_30020	7.17e-99	286.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,3WJGD@541000|Ruminococcaceae	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
BIFPGKOA_01430	718252.FP2_06210	1.39e-111	328.0	COG3503@1|root,COG3503@2|Bacteria,1V8H3@1239|Firmicutes,24JRC@186801|Clostridia,3WJIA@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
BIFPGKOA_01431	657322.FPR_30000	8.96e-278	759.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,3WGFB@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
BIFPGKOA_01432	657322.FPR_02230	2.23e-262	741.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25Q4H@186801|Clostridia,3WH43@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
BIFPGKOA_01433	657322.FPR_25980	3.29e-191	530.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3WGGF@541000|Ruminococcaceae	186801|Clostridia	F	IMP cyclohydrolase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
BIFPGKOA_01434	748224.HMPREF9436_02419	6.81e-107	310.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,3WIAG@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
BIFPGKOA_01435	657322.FPR_03930	2.91e-72	223.0	2E3FE@1|root,32YE8@2|Bacteria,1VFR0@1239|Firmicutes,24MNV@186801|Clostridia,3WJTE@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01436	657322.FPR_03940	2.57e-64	196.0	2DG94@1|root,337GI@2|Bacteria,1VHDH@1239|Firmicutes,24RH0@186801|Clostridia,3WKWR@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BIFPGKOA_01437	657322.FPR_03950	7.22e-207	573.0	COG2755@1|root,COG2755@2|Bacteria,1VCJD@1239|Firmicutes,25B7F@186801|Clostridia,3WS5V@541000|Ruminococcaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
BIFPGKOA_01438	657322.FPR_03960	6.37e-47	164.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
BIFPGKOA_01439	748224.HMPREF9436_02467	6.53e-97	283.0	COG4506@1|root,COG4506@2|Bacteria,1VCRX@1239|Firmicutes,24NFZ@186801|Clostridia,3WK9H@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1934
BIFPGKOA_01440	657322.FPR_16570	1.4e-196	545.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,3WGBW@541000|Ruminococcaceae	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
BIFPGKOA_01441	657322.FPR_16580	6.54e-175	492.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WGGM@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
BIFPGKOA_01442	657322.FPR_29940	2.49e-123	352.0	COG0454@1|root,COG0456@2|Bacteria,1VGZX@1239|Firmicutes,24I40@186801|Clostridia,3WMBR@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BIFPGKOA_01443	657322.FPR_29930	1.43e-173	484.0	COG2188@1|root,COG2188@2|Bacteria,1TQQQ@1239|Firmicutes,24C86@186801|Clostridia,3WJ26@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
BIFPGKOA_01444	657322.FPR_18430	5.57e-273	745.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,3WGDG@541000|Ruminococcaceae	186801|Clostridia	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
BIFPGKOA_01445	657322.FPR_18440	3.43e-155	435.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia,3WI50@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Mannitol_dh_C
BIFPGKOA_01446	657322.FPR_18450	1.81e-28	114.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
## 1284 queries scanned
## Total time (seconds): 198.4309380054474
## Rate: 6.47 q/s