LOCUS       gnlProkkaFDGPACDO_178   5352 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FDGPACDO_178.
ACCESSION   gnlProkkaFDGPACDO_178
VERSION     gnlProkkaFDGPACDO_178
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 06:03:43
            Original ID  :: gnl|Prokka|FDGPACDO_178
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5352
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5352
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3511:3769]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3512..3769
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..5352
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5352
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..959
                     /locus_tag="ctg178_1"
                     /transl_table=11
                     /translation="MFPVKDVKVMMVDRQEVTAGGEAIGIYVKTDGILVLGTAKIADAW
                     GNECSPAQNLVQSGDYIVSVNGETVCGKEELMDKIDSYGSGREIIGVMRKGEYVEVSMN
                     PVKGETGKYRLGIWVRDDLAGVGTLTYYRQDGSFGALGHAVSDGDTGVQMSLSEGYIYE
                     TKIVSIQNGKKGVPGELEGIIDSGKSHCMGSITDNSPLGIRGMLNDTAGELEGEVYEVA
                     YKQDIALGKAYIISEVSGERVEYEIEIESLDYSGDEENKGILFKVTDERLLDLTGGIVQ
                     GMSGSPIIQNGKMIGAVTHVFVSDASMGYGIFIEKML"
     CDS             1042..2502
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 140.2; E-value:
                     2.1e-42)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg178_2"
                     /transl_table=11
                     /translation="MEQQEHIQKLADEYYEEGRARFFDHKLEEAAMLVQNALRLYKKCD
                     DMLKYATALNLLGVIYGATGNETMAVDYLVEGLECAIDYQLNNITTLFYNNIGSRYQEL
                     GEHEKAIDYFLKSARELQNPTCIKEERYRSWALITYLNLAVSYYELNLYELSYKYLEQA
                     ERQLDEEVEEMYHYTVLIFKCRLLWQMGKGDYVYEYMEDLLASGEKDSNASDYLNDMKD
                     LCQLFRDMKEYEYWKQTISAVETYTIDQKTVFFQLFLTELWMDYYQTVGNEERYVELCV
                     AHADLYKRQKAIDAKDRATAIDIKVQLREKEAERKRVETMSVTDALTGLGNRYSLEREA
                     VHIIRDAGGERITVGVLDIDCFKQLNDTYGHIQGDRCLKVVADILKEAVMDCGHVYRFG
                     GDEFVMLFPAGMENRIEEIAEAILQKIAEAGIANEHSVVQPNLTISQGYACFVPEGTES
                     GARLIEHADKALYYVKRNSRNAYYIIRE"
     CDS             2600..3280
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 89.7; E-value: 3.4e-27)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg178_3"
                     /transl_table=11
                     /translation="MEKLNVAIADDNERMLRLLGDIIESDDELNVVGVARDGEEAYHVI
                     KAKEPDVVLLDIVMPKLDGLGVLDRVSQDTSIKKHPAFIMISAIGQEKITEDAFARGAD
                     YYIMKPFDNDIVLSRIKNVRRPAAGRGAEVRKVNAYEKAEETKERNLEADVTDIIHEIG
                     VPAHIKGYQYLRDAIVMSVNDMDMLNSITKILYPTIAKKYQTTSSRVERAIRGGVEQRQ
                     DGYH"
     CDS             3267..3386
                     /locus_tag="ctg178_4"
                     /transl_table=11
                     /translation="MDTIDEMFGYTIHNGKGKPTNSEFIALITDRIRLEYKMH"
     CDS             3512..3769
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg178_5"
                     /sec_met_domain="PF05402 (E-value: 2.5e-13, bitscore: 38.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.7e-10,
                     bitscore: 27.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKNRYQLRCAAGKYWLLDMEQDGETYRPPLMLNESGAYIFRQYT
                     AGNTADKIAEELATMYGRTADDMRTDVMQFIRQMELQGIL"
     CDS             3773..5350
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 63.6;
                     E-value: 3.4e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg178_6"
                     /sec_met_domain="RmlD_sub_bind (E-value: 4.6e-14, bitscore:
                     40.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILLVGSKCRFLQLLTDKLDKEGHRVFLLTAEDKSVRTSKKIFE
                     TYHFAYDNPCIREVLEGVRPDVTVFMGAYDTGFLWGKGSSTASAYTSGLFQLLMNETAG
                     NVGRFLYLSSEEVFGGEYTQDISCEENCAAYAVRAQAIAAGEELCRSYFNMGYETIVLR
                     LDHLYGEPLTGAEARDICARMSVEGLETGEIRVNPHNRVALLHYSDAVEFLYAVITAKK
                     MTYGVYQISSGETISVRSAAEFVAAELEGVKVVEDTGRERMEPVLSNQRFAEEFGIRIV
                     HKPETEIGREAAYIRQHASSFVRTQSRKKGWSRFGERSREAVRAMIPFAENLLCFLPFF
                     LLNNWMAGSAYFQNIDFYLLYVLLFAITYGQQQATFSSILAVAGYLAVQMYQRSGFDVV
                     LDVNTYIWIAQLLILGLVIGYMRDRLHAVEEEERHEVDFLSRQVEDISDVNGSNVRIKE
                     ILSKQIVNQNDSFGKLYEITSSLDKYEPSEVLFYAAEVLAKLMDSQDVAIYTVANHSYA
                     RLVSATSPK"
ORIGIN
        1 gcattttccc ggtaaaagac gtgaaggtga tgatggtcga cagacaggag gtgactgcgg
       61 gcggcgaggc gatcggtatc tatgtgaaga cggatggaat cctggtgctc ggcactgcaa
      121 agattgcgga tgcgtggggc aatgagtgca gcccggcgca gaatctggtg cagagcgggg
      181 attatattgt gagcgtgaac ggggagacgg tgtgcgggaa agaggagctg atggacaaga
      241 ttgacagcta cggcagcgga cgtgagatca tcggagtgat gcggaagggg gagtatgtgg
      301 aagtatccat gaatccggtc aaaggcgaga cgggaaaata ccgccttgga atctgggtgc
      361 gggatgatct tgccggggtc ggaacactga cctactacag gcaggacggc agctttggcg
      421 cactcggaca tgcggtgagc gacggcgaca ccggcgtgca gatgagcctg tcggaaggat
      481 atatttacga gacgaaaatc gtcagcatcc agaacggcaa gaagggcgtc ccgggcgaac
      541 ttgaggggat cattgactcc gggaaatcgc attgcatggg aagcattacg gacaactcgc
      601 cgcttggcat ccgcggcatg ttaaatgata cggcgggaga actggaagga gaagtctacg
      661 aggtggctta taagcaggac attgcgcttg gaaaagccta catcatctcg gaggtgtccg
      721 gggagcgcgt ggagtatgag atcgagatag agagtcttga ttacagtgga gatgaggaaa
      781 acaagggaat cctttttaaa gtcacggatg agcggctttt agacctgacc ggaggaatcg
      841 tacaggggat gagcggcagt ccaattatcc agaacggaaa gatgatcggg gcggtgacgc
      901 atgtgtttgt gtcggatgcg tcgatggggt acggaatctt tattgagaaa atgttgtgat
      961 tgtacgacaa aaacttttac aacgtctggt acttatggta tactacagtc agtattgttg
     1021 gctttaagga cggaagatgg aatggaacag caggaacata tacaaaaact ggcagatgaa
     1081 tactacgaag agggcagagc cagattcttt gaccacaagc tggaggaagc ggcgatgctt
     1141 gtacagaatg cgcttcgtct ctacaagaag tgcgacgaca tgttaaaata cgccacagcg
     1201 ctcaatctgc tcggggtgat ctacggcgcc acggggaacg agacgatggc ggtggattat
     1261 ctggtcgaag gacttgagtg tgcgatcgat taccagctaa ataacatcac gacactcttt
     1321 tataacaata tcggctccag gtaccaggag ctgggagagc atgagaaggc gatcgactat
     1381 ttcttaaagt cggcgcggga actgcagaat ccgacctgca tcaaggagga acgctaccgt
     1441 tcctgggctc tgattaccta cctgaatctg gcggtctcct actacgaact gaacctgtac
     1501 gagctttcct acaaatattt agagcaggca gagcggcagc ttgacgagga agtggaggag
     1561 atgtatcatt atacggtact gatcttcaaa tgtaggctgc tctggcagat gggaaagggg
     1621 gactatgtgt atgagtacat ggaggacctt ctggcgagcg gtgaaaaaga cagcaatgcg
     1681 tcggattatc tgaacgatat gaaggatctg tgtcagctgt tccgcgacat gaaagagtat
     1741 gaatactgga agcagaccat atctgcggtc gagacctata cgatcgatca gaaaaccgtc
     1801 tttttccagc tgtttctgac ggaattgtgg atggactact atcagactgt ggggaacgaa
     1861 gagcgctatg tggaactgtg tgtggcacat gcggatctgt ataagcgcca gaaagcgatc
     1921 gatgcgaagg accgcgccac agcgatcgac atcaaggtcc agctgcggga aaaagaggcg
     1981 gagcgcaagc gtgtggagac tatgtctgtg acggatgcgc tgaccgggct ggggaaccgc
     2041 tattctcttg agcgtgaggc agtgcatatc ataagggatg cgggcggtga gcggatcacg
     2101 gtcggcgttt tggacatcga ctgctttaag cagctgaacg atacctacgg gcatattcag
     2161 ggagaccgct gcctgaaggt ggtggcggat attctgaagg aggcagtgat ggactgcgga
     2221 catgtctacc ggtttggcgg ggatgagttc gtgatgttgt ttccggcagg gatggagaac
     2281 cggatcgagg agatcgcgga ggcgatcctg cagaagattg cggaggcggg aatcgcaaac
     2341 gagcactcgg ttgtacagcc gaatcttact atctcccagg ggtatgcctg ctttgtgccg
     2401 gagggcacag agagcggagc gcgtctgatt gagcacgcgg acaaggcgct ttactatgtg
     2461 aagagaaaca gcagaaatgc atattatatc atacgcgaat gatgcatata cttcagttga
     2521 cgacttgctt cgacaaattt tcttgcgttg gaatcagtat catcagtaag caaagagttt
     2581 tgtcacagga ggggctaaaa tggaaaaact gaatgttgca atagcagatg ataatgagag
     2641 aatgctgcga ttattagggg atattatcga aagtgatgac gaactgaatg ttgtaggagt
     2701 cgcccgcgac ggcgaggaag cataccatgt gataaaggcg aaagaaccgg atgtcgtgct
     2761 gctcgacatt gtgatgccga agcttgacgg attgggggtt ttagaccggg tgagtcagga
     2821 cacctccata aaaaaacatc cggcgtttat tatgatcagc gcgatcggtc aggagaaaat
     2881 cacggaagat gcgtttgcgc gcggcgcaga ttattacatt atgaagccgt ttgacaatga
     2941 tatcgtgtta agccgcatca agaatgtgag aagacctgcg gcgggacgcg gtgcggaagt
     3001 gcgcaaggtc aatgcctatg agaaggcgga ggagacaaag gagcgcaacc tggaagcgga
     3061 tgtcaccgat attattcacg agatcggagt tccggcgcat attaaagggt atcagtatct
     3121 gcgggatgcg attgtcatgt ccgtcaatga catggatatg ctcaactcga tcacgaaaat
     3181 tctttatccc acgattgcga agaagtacca gacaacctcc agccgtgtgg agcgggcaat
     3241 ccgaggtggc gtggagcaga ggcaagatgg ataccattga tgagatgttc gggtatacca
     3301 tccacaacgg aaaaggaaaa ccgacgaatt cggagtttat cgcactgatt accgaccgga
     3361 tacgtctgga atataagatg cattaacgat gaggacatat ttttcaggag gcgcaaagcc
     3421 gaagaagagt atgtcctcat tttcggataa ccggttcctt ttgagcgtca gatgtgctat
     3481 aattatacga tgatttttcg gaggatggca gatgcagaaa aacaggtatc agctcaggtg
     3541 cgcggcagga aaatactggc tgttagatat ggagcaggat ggagaaacgt atcggccgcc
     3601 gctcatgtta aatgagagcg gggcttatat cttcaggcag tatacggcag gaaacacggc
     3661 ggataaaatc gcggaggagc ttgccactat gtacgggagg accgcagacg atatgcggac
     3721 agatgtgatg cagtttatca gacaaatgga actacagggg atcttgtaaa cgatgaatat
     3781 attattggtg ggaagcaaat gccgcttcct tcagcttttg acggacaaac tggacaaaga
     3841 agggcaccgt gtgtttttgc tgacggcaga agacaaatcg gtcagaacgt ccaaaaagat
     3901 atttgagacg tatcattttg catacgacaa tccgtgcatc agagaggtgc ttgagggagt
     3961 gcgtccggat gtgacagtct ttatgggcgc ctatgataca ggctttctct gggggaaggg
     4021 gagcagcacg gcgtcggcgt acacttcagg cctgtttcag ctgctgatga atgagacggc
     4081 tggtaatgtg ggacgctttt tgtatctctc gtcggaggaa gtcttcgggg gagagtatac
     4141 acaggacatt tcgtgcgagg aaaactgtgc ggcttatgcg gtacgcgcgc aggcgattgc
     4201 ggcgggagag gaactctgcc gcagttactt taacatgggc tatgagacga tcgtgctgcg
     4261 gctggatcat ctctacgggg aaccgcttac cggggcggaa gcgcgtgata tctgcgcccg
     4321 catgagtgtg gaggggctgg aaaccggtga gatccgggta aatccccaca accgtgtggc
     4381 gctgttacac tattcggatg ccgtcgaatt tttgtatgcg gtgattacgg caaaaaagat
     4441 gacgtacggc gtctatcaga tttcttccgg agagacgatt tccgtgcgaa gcgcagcgga
     4501 gtttgtggcg gcggaactgg aaggtgtgaa agtcgtagag gacaccggaa gagagcggat
     4561 ggagccggtt ttgtccaacc agagatttgc ggaggagttt gggatacgca ttgtacataa
     4621 gccggagacc gagattggca gggaggcggc gtacatccgg cagcacgcat cttcttttgt
     4681 gcggacacag agcagaaaaa agggatggag ccggtttgga gagcggtcga gagaggccgt
     4741 aagagcgatg attccgttcg cggagaatct gctttgtttc cttccgtttt tcctgttaaa
     4801 taactggatg gcggggagcg cgtatttcca gaacattgat ttttaccttc tgtatgtgct
     4861 gctgttcgcc attacctacg ggcagcagca ggcgacattc tcctcgattc ttgcggtggc
     4921 ggggtatctt gcggtgcaga tgtatcagcg gagcggtttt gatgtggtgc tggatgtcaa
     4981 cacgtacata tggattgcac agctgctgat tctgggactt gtgatcggct atatgcgcga
     5041 ccggctgcat gcggtggagg aggaggagcg ccatgaggtg gatttcctct ccagacaggt
     5101 ggaggacatc tcggatgtca acggcagcaa cgtgcgcatc aaggagattc tgtcaaagca
     5161 gatcgtcaac cagaacgata gcttcggaaa gctgtatgag atcacgtcca gcctggacaa
     5221 gtacgagccg agtgaagtgt tgttctatgc cgcagaggtg ctggcaaagc tgatggacag
     5281 tcaggatgtc gcaatctata cggtggcaaa ccactcctat gcgcgtctgg tctcggcaac
     5341 ttcgccgaag gc
//
