LOCUS       c00025_gnlPro..        15532 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FDGPACDO_25.
ACCESSION   c00025_gnlPro..
VERSION     c00025_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 20:54:14
            Original ID  :: gnl|Prokka|FDGPACDO_25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15532
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15532
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2397:5532]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2398..5532
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15532
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15532
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             3..890
                     /locus_tag="ctg25_1"
                     /transl_table=11
                     /translation="NAYAKYYGGIERYFTPFVANKKLGHREKNDVCPEHNAGMAVVPQI
                     LTNRAEDFLAIAEILREYGYDTVNLNLGCPSGTVAARGRGAGFLAMPDELDHFLEEIFE
                     KCPLRISIKTRIGKENPAEWERLLAIYEKYPLEELIVHPRVQTDFYKNRVNLEAFARAE
                     KNSRHSLCYNGDIVDAASAAHIREGFPSVDKFMIGRGLIKHPWLLEELSGGRQEKQERK
                     ERFFRFHNAILEGYRQQMSGDKNTLFKMKELWAYWGENFADADQRLKKIRKCERVAEYE
                     CLVDALFREKELCV"
     CDS             1077..1994
                     /locus_tag="ctg25_2"
                     /transl_table=11
                     /translation="MESYTLEEKVLRKVMRNIPMGLIVSKEGFRRKIYYVNDTACEIMG
                     YTREEYIRKMQDGWADLMDVDLREVIREHNEQIRSGTPFEVLSRPQTKNGGYKWILSRV
                     NVQMQEGPLCYVSFMDVTDRMEREELCRQENEVLREQAMQDSFTKLLNRGALEKHVCEA
                     LQERGGDEEDAFILLDVDNFKQINDIYGHGVGDMILMRMAGILNEVFGDHSCIGRMGGD
                     EFAVFLRDIGDRREIEEKIQKLLTEVRAEKERMHLNKEPTASVGIAFVPESGSTFVDVY
                     RAADQALYHVKNSTKNGMAFYDFV"
     CDS             2398..4626
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_3"
                     /sec_met_domain="Gly_radical (E-value: 3.2e-46, bitscore:
                     146.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 4.6e-282, bitscore:
                     926.6, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNEWRGFQRGSWEEEINVRDFIQKNYTPYDGDDSFLEGPTQDTT
                     DLWNEVLELSKQEREAGGVLDMDTKIISTITSHGPGYLDKNKEKIVGFQTDKPFKRSLQ
                     PYGGIRMAVKACEDNGYHVDPEVVEYFTTHRKTHNAGVFDAYTPEMRACRSAHIITGLP
                     DAYGRGRIIGDYRRPALYGVDRLIEDKEEQLATTRTIMYSDVIREREELSEQIRALKML
                     KELAKIYGCDISKPANNVLEATQAVYFSYLAAVKEQNGAAMSLGRTSTFLDIYAERDLK
                     EGTFTEKEIQEIIDQFVMKLRCVKFARTPEYNSIFAGDPTWVTESIGGIGVDGRHMVTK
                     MSYRYLNTLNNIGAAPEPNMTVLWSVQLPENFKRFCAQTSIRHSAIQYENDDIMRVVHG
                     DDYGIACCVSSMRIGKEMQFFGARANLAKCLLYAINGGVDEISGKQVGPKYRPITSEYL
                     DYDEVWDKYKDMMKWLAGVYVNALNIIHYMHDKYCYEKLEMALHDKKVRRWFATGIAGF
                     SVVADSLSAIKYAKVKPIRDENGITVDFEVEGDFPKYGNDDDRVDDIAKEVLHTFIGYV
                     KGNHTYRGGIPTTSILTITSNVSYGKNTGATPDGRKKGVAFAPGANPMHGRDTNGAVAS
                     LASVAKMPFMDSQDGISNTFTIVPDALGKDETGEEQNLVALLDAYVEKGGHHLNVNVLN
                     RETLLDAQKHPEQYPQLTIRVSGYAVNFIKLTKEQQDEVIARTFHERM"
     CDS             4771..5532
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 77; E-value:
                     5.5e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_4"
                     /sec_met_domain="Radical_SAM (E-value: 6e-33, bitscore:
                     104.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKIHSMESFGTVDGPGVRFVVFFGGCPMRCLYCHNPDTWHLEDG
                     QEMSAEEILSRMERNRSFYRTGGITATGGEPMLQIDFLTELFAGAKERGIHTCLDTSGI
                     MFPGCGGTSEEERERLKKVDMLLSVTDLVMLDIKHMDAEEHRKLTGQDNEKILAFARYL
                     DEKQIPVWIRHVVVPGITFQREELEALGRFLATLSNVEKLEVLPYHSMGKVKYDNLGMD
                     YALKDTPQLTKAEAKSAESIILEAMRQARNV"
     CDS             5727..5963
                     /locus_tag="ctg25_5"
                     /transl_table=11
                     /translation="MKIKNITDIDGFFKVIDSCQGKVELITGEGDRLNLKSKLCQYVSL
                     TSILKTDVEIPELELVAYEPEDTEKIIKFLMKG"
     CDS             6032..7783
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_7"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_6"
                     /sec_met_domain="Acetyltransf_7 (E-value: 1.3e-10,
                     bitscore: 31.6, seeds: 2199, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPEETVFHEITLQDKAWMDRKFAEDDRNACEYSFANNFMWRNVY
                     QVRVAELHGCLVVRFIDGEIHCFSFPVGNGDKKAAVEELLAICHEEGIQLLIAPASEQD
                     RAQMLEWFPGRFLIEGDRNDYDYIYTREKLATLAGKKLHGKRNHIARFKDSGDWSYEPM
                     TAENVEECRTMTYTWIHMREEKWNEEMNQEISVLHEAFDHMQELGLVGGVLRRDGQIVA
                     FSIGERLNSETFVVHFEKAYPDLQGAYPMINQQFVLHECEGYAYVNREEDTGDPGLRKA
                     KLSYYPDILLPKYELEESGVVYADPERDAPYIQEIWQKCFGDEEDYIQFYLKHRMTREN
                     MLVIFRDGRPVSMASFLPVKYLCSGAYVDARYVYAVATLPEYRGQKLAEQILRFAEEKY
                     QVPLILSPAEESLTRYYEKLGFKNAFQGEHKNVSGSDITALEVKDTEPVACMEPVTPEE
                     YVRIRDEKCAKEGYVHWDVDAVSYAMELAASCGGGTAAVSCEDINTRNEQEDDRDILMY
                     DIREKELVILETTLSDDALSQVLPQLMEETGTSAASYGRERGMIWLPETMADLPVAGDG
                     YLALTLG"
     CDS             7902..8432
                     /locus_tag="ctg25_7"
                     /transl_table=11
                     /translation="MRIKITGRNIELTEGLKAAVEDKLNKLEKYFTPDTDVYVTLSVEK
                     ERQKAEVTIPAKGNYIRSEQVSNDMYVSIDLVEEVIERQLKKYRTKLVTKQQNASAVFK
                     QEFLDGAADEDEEIKIIRTKKFSMKPMYPEDACVQMELLGHDFFVFINAETEDVNVVYK
                     RKGNTYGLIEPEN"
     CDS             8739..8987
                     /locus_tag="ctg25_8"
                     /transl_table=11
                     /translation="MQNYPGFMDYIAYQYPLEGERIELLEQILTALAVGRKLEAEQMIY
                     HYGSMIHGRDLIARQVFLWLLGMAEYSRRECIAEERR"
     CDS             9112..10167
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_9"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 3.6e-54,
                     bitscore: 173.3, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_N (E-value: 2.6e-27,
                     bitscore: 85.3, seeds: 635, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIVVLAGGLSTERDVSFKTGEMVTKALRENGHQVILLDVFMGYS
                     DKEEDLTGIFDRAEAVSVKVAAIPETAPNLEKVKAQRKDQSDNFFGPNVIELCRMADIV
                     FMALHGENGENGKIQAAFDLFGIRYTGTGYLGSALAMNKGMAKQLFLENGIPTPRGTSL
                     KRGEDAAKIETCGIHFPCVVKPCSGGSSIGVSIVHDKAEYEQALKEAFRWENELVIEEY
                     VKGREFSVGVIDFQALPIIEIAPVEGFYDYKNKYKAGSTVETCPAELSEQITKEMQGYA
                     EKVAEVLGLNTYSRTDFLLDAEDHIFCLEANTLPGMTPTSLLPQEAKVTGVDFNQLCEK
                     LIESSMRKYKN"
     CDS             10194..11612
                     /locus_tag="ctg25_10"
                     /transl_table=11
                     /translation="MKNMTLEHIAQACGGTYIGEECDRKKEIQGAVIDSRLVGEGYLFI
                     PIRGARVDGHDFIPAVFEKGALAVLSEQRLEHPAGPYILVDSTEEAMKKIAAFYRRSLD
                     IKVVGITGSVGKTSTKEMIASVLSEKYRVLKTEGNLNNEIGLPLTIFKIREEHQVAVLE
                     MGISEFGEMHRLAEMAQPDICVITNIGLCHLENLITRDGILKAKTESFEHLAPDGIAVL
                     NGDDDKLCDKKMVNGRPAVFYGIGQEAKTAETETGSKRLAEKEVYATDVEAIGLEGTKA
                     VIHTPEQQFEVVIPIAGEHNVYNALAAVCVARRLGLDAEEMKLGIEHAHTIGGRSNLIR
                     KNGITIIDDCYNANPVSMMASIDVLSQAKGRKIAVLGDMGELGSEEKKLHGMVGTHFAG
                     KKIDALFVTGTLAGEIAEEARRVAPETRVYAEPDKEALEEALLEYRRPGDTILVKASHF
                     MGFSEIVKKLEQPQ"
     CDS             11628..12134
                     /locus_tag="ctg25_11"
                     /transl_table=11
                     /translation="MKKNIILIGMPGVGKSTVGVVLAKVMGYQFIDADLVIQEKEGKLL
                     REIIAEVGPEGFLKVENRINSGIEAEHAIIATGGSVVYGAEAMEHLGRIGTVVYLKLPY
                     RELERRLSDIKGRGVVLRDGQTLHDLYEERVPLYEKYADVIVDEHHLNVEQTIEKIMEL
                     KERFQ"
     CDS             12131..13687
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M23"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_12"
                     /sec_met_domain="Peptidase_M23 (E-value: 1.4e-38, bitscore:
                     121.0, seeds: 243, tool: rule-based-clusters)"
                     /sec_met_domain="LysM (E-value: 1.1e-10, bitscore: 31.4,
                     seeds: 155, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQTFTKQAVWQAAAVGVLAVGGVLFCLSGQIGIGQTYRQVRVD
                     DRIIGYAPENTDMDDIVRQARQELTQKTGERISGEVVWSSEECRKPFQKLLSENELKEA
                     VENILSEKNAEEKQRVYTVAIDEYRANFATMDEVESFLEKVKASADAADEYGAVIADQG
                     SHVSGILTASLARRDAGAAADEKVLEEAQASLPQAGISAYVICTLEEAFADPKATYETG
                     ILDMEFVERVNVFENYVDANQIADVDEQVAEVTKEKESNKIYVVESGDCLSVIAMDHDT
                     TVSSIVALNGLDSADAMIRDGQELIIAVPEPDLQLRVTKGEVYEEDYTEEPIIIDNDSW
                     YTTKEVVQQEGTTGHRERNDVVVYENGVETSREMIHQNVMVASQAAVIERGTIIPPTYI
                     KPISGGRYTSGFGRRWGRMHKGVDWACPIGTTVYASCAGTVISASYNGGYGNNVVISHA
                     DGRLTRYAHNSKLLVKAGQHVEQGEPIALSGSTGRSTGPHVHFEIYINGSAVDPLKYIS
                     N"
     CDS             13858..15150
                     /locus_tag="ctg25_13"
                     /transl_table=11
                     /translation="MEQYVIKGGNPLVGEVEIGGAKNAALAILSAAVMTDETVTIENVP
                     NVRDTNVLLNAIEEIGARVERLDAHTVRINGSFIRDFNVDNEFIRKIRASYYLIGALLG
                     KYKRAEVALPGGCNIGGRPIDLHMKGFRALGADVDIKYGLVRAYAEKLTGTHIYLDKVS
                     VGATINIMMAASMAEGKTIIENAAKEPHVVDVANFLNSMGANIRGAGTDVIRIVGVEKL
                     HATEYSIIPDQIEAGTFMLAAAATKGDVTVKNVIPKHLEAISAKLLEIGCEVEEFDDAV
                     RVVASKPLRHTQVTTLPYPGFPTDMQPQMTVVLGVAQGTSTVTESIFENRFKYVDELTR
                     MGASIKVESNIAIISGVDQYTGARVNAPDLRAGAALVIAGLGAEGITVVDDIYYIERGY
                     EAFDQKLSLLGALIEKVSDEKEIQKFTLKVS"
ORIGIN
        1 ggaatgcata cgcaaaatat tacggcggga tcgaacgcta ttttacgccg tttgtggcga
       61 ataaaaagct tggacaccgg gagaaaaatg acgtctgccc ggaacacaat gcgggaatgg
      121 cggtcgttcc gcagatactt acgaaccgcg cagaagattt tctggcgatc gcagagattc
      181 tgcgggagta tgggtacgat acggtcaacc tgaacctcgg ctgcccgtcg ggcacagtgg
      241 cggcaagagg gcgcggcgcc ggattccttg cgatgccgga cgagctggat cattttctgg
      301 aagagatttt tgaaaaatgt ccgctccgga tctccatcaa gacacggatc ggaaaagaga
      361 accctgcaga atgggagcgg ctgcttgcca tatatgaaaa atatccgtta gaagaactga
      421 tcgtacaccc gagggtgcag accgattttt ataagaaccg ggtcaatctg gaggcatttg
      481 cacgggcaga gaaaaacagc agacattcgc tctgttataa tggtgacatt gtggacgcag
      541 cgtccgcggc gcacatccgg gagggctttc cgtcggtgga taagttcatg atcggccggg
      601 gcctgataaa gcacccctgg cttctggagg aactttccgg cggcagacag gaaaagcagg
      661 agcgaaaaga gcggtttttc cggtttcaca atgcgatcct ggagggatac cggcagcaga
      721 tgtccgggga caaaaatacc ttatttaaga tgaaggaact gtgggcgtac tggggagaga
      781 actttgcgga tgcggaccag cgtctaaaaa aaatccgaaa atgtgagcgg gttgctgagt
      841 atgaatgtct ggtggacgcg ctgtttcgtg aaaaagagct gtgcgtgtag gaaaagagtg
      901 gggtatgcgg caatagattt gtgtgatata acaaaaaaga ggctttccaa tctgtaacat
      961 ttatataaaa agacgaaagg gactttttat ttgctgtaaa aagtattata ctgtactccg
     1021 tagtatgctt catgagaacg ataggggaat tggggaagag gttttaaaga gggtatatgg
     1081 aaagctatac gttagaggag aaagtgcttc gcaaggtcat gcggaatatt ccgatgggac
     1141 tgattgtgag caaagagggg tttcgacgca agatttatta tgtcaatgac acggcgtgtg
     1201 agattatggg gtacacgcgg gaagagtata tcagaaagat gcaggacgga tgggcggatc
     1261 tgatggatgt cgatctgcgg gaggtcatcc gcgagcacaa tgagcagatc cgctccggga
     1321 caccgttcga ggtgctctca agaccacaga cgaagaacgg cggttacaag tggatattaa
     1381 gcagggtgaa tgtgcagatg caggagggac cgctctgtta tgtcagcttt atggatgtca
     1441 ccgaccggat ggagcgggag gaactgtgcc ggcaggagaa cgaggtgctc agggagcagg
     1501 cgatgcagga ctcctttacg aagcttctaa accgcggcgc gctggagaag catgtctgcg
     1561 aggcgcttca ggagagaggc ggcgatgagg aggatgcatt cattcttctg gatgttgata
     1621 attttaagca gatcaatgac atttacggtc acggagtcgg ggatatgatt ctgatgcgga
     1681 tggcgggaat tttaaacgaa gtgtttggag accattcctg tatcggcagg atgggcggcg
     1741 atgaatttgc tgttttcctc agagacatcg gcgaccggag agagattgaa gagaagattc
     1801 aaaagcttct tacggaggta cgcgccgaaa aagaacggat gcacttgaac aaggaaccga
     1861 ccgccagcgt cggcattgca tttgtgccgg aatcgggaag cacgttcgtg gatgtgtacc
     1921 gggcggcgga tcaggcgctg tatcacgtga agaactcgac aaagaatgga atggcgttct
     1981 atgattttgt ataatttttc ctattgaaaa aaatcatcat atactgtaag attaagatgt
     2041 tatatgactg acggaacaag tggaagaacc acatggagta taacgtatct aatgccgacc
     2101 gtctgggcga atgtacccgg gcagtcggct tgttttgaat cagggggctt tttatcgaaa
     2161 aagcacccgg gattctcacc tctgagacaa aagatgcttt ggctcaaaaa gcataaaata
     2221 cccactgaga gtaaggcaag acaaacacgc ctggcaacaa aacttgatat tgacagtgaa
     2281 aagcactcta tgctatagtc ataaaggtta gctgtaacta actaatatca tgttttggca
     2341 atgctgcctg cgggcaggga acataatcac attacaaagt aagcaggagg aagaatcatg
     2401 cagaatgaat ggagaggctt tcagcgggga agctgggagg aagagatcaa tgtcagagat
     2461 tttatccaga aaaactatac gccttacgac ggggacgaca gctttctgga aggaccgacg
     2521 caggatacga cagatttatg gaacgaagtg ttagaactgt cgaagcagga gcgtgaggca
     2581 ggcggtgtcc tcgatatgga taccaagatt atttccacga tcacatccca tggaccgggc
     2641 tatctggaca agaataagga gaagattgtc ggctttcaga cagataagcc gttcaaacgt
     2701 tctctgcagc cgtacggcgg aatccgtatg gcagtgaaag cctgcgagga taacggctac
     2761 catgtagatc cggaagtggt ggaatatttt accacgcaca gaaagacaca caacgctggt
     2821 gtatttgatg cctacacacc ggagatgcgc gcatgccgtt cggcacatat catcacggga
     2881 cttccggatg catatggacg cggacgtatc atcggcgatt acagaagacc ggcactctac
     2941 ggtgtggacc gcctgatcga ggacaaggaa gaacagctcg caacgacccg tacgatcatg
     3001 tactcagatg tcatccgtga gcgtgaggag ctttccgagc agatccgcgc actcaagatg
     3061 ctgaaagagc ttgcaaagat ttacggctgt gacatttcca agccggcgaa caacgtgctg
     3121 gaagcgacgc aggcggtata tttttcctac cttgcagcag tcaaggagca gaacggtgcg
     3181 gcaatgagcc ttggacgtac ctccacgttc ctcgacatct atgcggagcg tgatctcaag
     3241 gagggaacat tcacagagaa ggagatccag gagatcatcg accagtttgt catgaagctg
     3301 cgctgcgtga agtttgcacg tacgccggag tacaactcca tcttcgccgg agatccgacc
     3361 tgggtgacgg agtcgatcgg cggaatcggt gtggacggca gacatatggt gacgaagatg
     3421 tcctaccgct atttaaatac actcaacaac atcggagcag cgccggagcc gaatatgacc
     3481 gtgctctggt cggtacagct cccagagaac tttaagcgtt tctgcgcaca gacatccatc
     3541 aggcactctg cgatccagta cgagaatgat gacatcatgc gtgtggtaca cggggatgat
     3601 tacggaattg catgctgtgt atcctccatg cgcatcggta aggagatgca gttcttcggc
     3661 gcccgcgcca accttgcaaa gtgccttctg tacgcgatca acggcggtgt agatgagatc
     3721 agcggcaagc aggtcggacc gaagtaccgc ccgatcactt ccgagtacct ggattacgac
     3781 gaggtgtggg ataagtataa ggatatgatg aagtggctgg caggtgttta tgtcaatgcc
     3841 ttaaacatca ttcattatat gcatgacaaa tactgctacg agaagctgga gatggcgctt
     3901 catgacaaga aggtgcgccg ctggttcgcg accggaatcg ctggtttttc cgttgtggcg
     3961 gattccctgt ctgccatcaa gtacgcaaag gtaaagccga tccgcgatga gaacggaatc
     4021 actgtagact tcgaggtgga gggtgacttc ccgaaatacg gaaatgatga cgaccgcgtc
     4081 gacgacattg caaaggaagt gcttcacaca ttcatcggct atgtcaaggg caaccacacc
     4141 taccgcggcg gaatcccgac gacatcgatc ctcacgatca catccaacgt atcctacggc
     4201 aagaacacag gtgcgacacc ggatggcaga aagaagggtg ttgcctttgc accgggcgca
     4261 aacccgatgc acggacgcga cacgaacggt gcggtagcat ctctcgcgtc ggtagcgaaa
     4321 atgccgttta tggattccca ggatggtatc tccaacacgt ttaccatcgt gccggatgca
     4381 ctcggcaagg atgagacggg cgaggagcag aaccttgtgg cgctgctgga tgcttacgtc
     4441 gagaagggcg gacatcactt gaacgtcaac gtattgaacc gcgagacgct tttggatgca
     4501 cagaaacacc cggagcagta tccgcagctc acaatccgtg tttccggata tgcggtaaac
     4561 tttatcaagc tgaccaaaga gcagcaggac gaagtcattg caagaacctt ccacgagcgc
     4621 atgtagttcg tgtggaagtg atacagacag gataaatcgc gcgaaccgga accggtgccc
     4681 tgctgctttt gcggcgggga caccgggata agccggctcg cgcgattgca ttatgaatat
     4741 cagacggatg ggatcaaaaa ggaggacttt atgggaaaaa ttcattcgat ggaaagcttt
     4801 ggaactgtgg atggaccggg agtccgcttt gtggtgttct ttgggggatg tcccatgcgc
     4861 tgcctgtact gccataatcc cgacacctgg catctggagg atgggcagga gatgagcgcg
     4921 gaagagattc tgtcacgcat ggagcgcaac cggtcgtttt accggaccgg cggaatcact
     4981 gcgaccggcg gagagccgat gctccagatt gattttttga cggagctctt tgcaggggca
     5041 aaggaacgcg ggattcatac ctgtctggac acgtcgggca ttatgttccc cgggtgtggc
     5101 ggcacgtcgg aggaggagcg ggaacgctta aagaaggtgg atatgctgct ctcagtgacg
     5161 gatcttgtga tgcttgacat caaacatatg gatgcggagg agcaccggaa gctgaccgga
     5221 caggacaatg agaagattct tgcgtttgca aggtatctgg atgaaaaaca gataccggtc
     5281 tggatccggc atgtggttgt tccggggatc acgttccaga gggaagaact ggaggctctg
     5341 ggacggtttc ttgcgacact ttcaaatgtg gaaaaactgg aggtgcttcc gtatcactcc
     5401 atgggaaaag tgaaatacga caaccttggc atggattatg cattaaaaga tacgccgcag
     5461 ctcaccaagg cggaggcgaa gagcgcggag agcatcattc tggaggcaat gcgtcaggcg
     5521 agaaacgtct gaccgtcaga cctgattgta taaaaaaata ctggaaatgc aattcagaag
     5581 gaaagccgtc aggcgaggga aagctggaaa acacggctgg gacgttgaag gaacatattt
     5641 ccaggtttac gatttagaac ttgcagaaga ggtactttcg tattatagtg tagatagaga
     5701 cacagattaa gaaaggagca tgtattatga agatcaagaa catcacggat atcgacggat
     5761 tttttaaggt aatagactcc tgccagggaa aagtggaact cattaccggc gagggggaca
     5821 gactgaacct caagtcaaag ctttgtcagt atgtatcact taccagtatt ttaaagacgg
     5881 atgtggagat tccggagctt gagcttgtcg cttacgagcc ggaagataca gagaaaatta
     5941 ttaagttcct gatgaagggc tgagaaaaag aaccgtcaac acaggttggc ggttctttta
     6001 tgtcttttta aaatttagaa ttgaggtatt tatgaaacca gaagaaacag tatttcacga
     6061 gataacactg caggataagg catggatgga ccggaagttc gcggaggatg accggaatgc
     6121 ctgcgaatac tcgtttgcaa ataattttat gtggagaaat gtctatcagg tcagagtggc
     6181 ggagctccac ggctgtctgg tagttcggtt tatagatgga gagattcact gcttttcatt
     6241 tccggttgga aacggcgaca aaaaagcggc ggtggaggag ctgcttgcga tctgccatga
     6301 ggagggaatc cagctgctga tagcgcctgc cagcgagcag gaccgcgcgc agatgctcga
     6361 gtggttcccg ggaagattct taatcgaggg agaccggaac gactatgact atatctatac
     6421 aagagagaag cttgcgacgc ttgccggcaa gaaactgcac ggaaagcgca atcacattgc
     6481 ccgctttaaa gattcgggag actggtctta tgagccgatg accgctgaga atgtagaaga
     6541 atgccgcacg atgacgtata cgtggattca catgcgcgag gaaaagtgga atgaggagat
     6601 gaaccaggag atctcggtac tccatgaggc gtttgaccat atgcaggagc ttggacttgt
     6661 cggcggagtg ctccggagag acgggcagat cgtcgcgttt tcaatcgggg agcggctgaa
     6721 ttcggagacg ttcgttgtgc attttgaaaa ggcgtatccg gatcttcagg gagcgtatcc
     6781 gatgatcaac cagcagtttg tcctgcatga atgtgaaggg tatgcgtatg tcaaccgcga
     6841 ggaggacact ggcgatcccg gactcagaaa ggcaaagctt tcctattatc cggatattct
     6901 ccttccaaaa tacgaactgg aggagagcgg ggtggtctat gcggaccccg agcgggatgc
     6961 accgtatatc caggaaatct ggcagaaatg ttttggcgac gaggaagatt atattcagtt
     7021 ttatctgaag caccgcatga cgagagagaa catgctcgtg attttccggg atggaagacc
     7081 ggtatcgatg gcaagttttc tgccggtgaa gtacctgtgc agcggggcgt atgtggacgc
     7141 gcgctatgtg tatgcggttg cgacactgcc ggaataccgg ggacagaagc ttgcggaaca
     7201 gattctgcgt tttgcggaag aaaaatatca ggtgccgctc attctgtcgc cggcggagga
     7261 atcgctgacc cgttactatg agaagctggg atttaagaat gcgtttcagg gagaacacaa
     7321 aaatgtgagc ggcagtgaca ttacggcgct cgaggtaaag gacacggagc cggttgcatg
     7381 catggagcct gtcacaccgg aggagtatgt gcggatccgg gatgaaaagt gcgcgaagga
     7441 agggtatgta cactgggatg tggatgcggt ttcctatgcg atggaactcg cggcaagctg
     7501 cggcggcggt acggcggcag tcagctgtga ggatataaac acacggaatg agcaggaaga
     7561 tgaccgggat attctgatgt atgatatccg ggaaaaagag ctcgtgatac tggagacaac
     7621 gctgtcggac gacgctctct cacaggtgct tccgcagctt atggaagaga cgggaaccag
     7681 cgcagcatcg tacggacggg agcggggcat gatctggctg ccggagacga tggcagatct
     7741 gccggttgcg ggcgacggtt atctcgcact gacgcttggt tgatgaattt tcagaaaaaa
     7801 ttatgaaaaa tgcataaatt ttcttgctat aaagccaaaa tatgttataa tataaccatg
     7861 atatatcttg tatcaaataa acggcaaagg ggttggacat catgagaatt aagattacag
     7921 gaagaaacat cgaattaaca gaggggctga aggcagcagt agaggacaag ctgaacaagc
     7981 ttgagaagta ttttacaccg gataccgatg tatatgtgac gctgagcgtg gagaaggaga
     8041 gacagaaagc cgaggttaca atcccggcaa aaggaaatta tatccgctcc gaacaggtaa
     8101 gcaacgatat gtatgtatcc attgatcttg tggaggaagt gattgagcgt cagcttaaga
     8161 aatacagaac caagctggtg acaaagcagc agaatgcatc cgctgtattt aagcaggaat
     8221 tcctggatgg agccgcagac gaggatgagg agatcaagat catccgtacc aagaagttct
     8281 ccatgaagcc gatgtatccg gaagatgcat gcgtgcagat ggaactgctg ggacacgact
     8341 tcttcgtatt catcaatgca gagacggaag atgtcaatgt ggtatataag agaaaaggca
     8401 acacctacgg actgatcgag ccggagaatt aagagcgttt gagatgtgct gtctcataat
     8461 gaactgataa ataataagag tgaagaagag ggagaaccgt attgcagatg cggcactccc
     8521 tcttcttttt gtggagaaaa aggagtttga gctgacagag ggcgctttct gtaaaatttt
     8581 ttgtgcaaag gggtgtacag ttagtactaa agtatcttat aattgtagtt aagcgcgccc
     8641 tgcgtgtgcg agaggtagaa aagttaatca tgtgtgaaac aaaagaaaag ggctcaagta
     8701 ggaaaagcta cggacataca aatgtattgg tggatatgat gcagaattat ccggggttta
     8761 tggattatat tgcatatcag tacccattgg agggagaacg gattgaatta ttggaacaga
     8821 ttctgaccgc gcttgcggtt ggaagaaagc tggaagcgga gcagatgatt tatcattatg
     8881 gcagtatgat tcacgggagg gatctcattg cgaggcaggt ttttctgtgg cttttgggga
     8941 tggcagaata cagcagacgt gagtgtatag cggaagagcg tagataaaaa gcaggaaagg
     9001 ggtcgcagcg caggggcaga gctttgaaaa aacaaggaat attcttgtca tcagatcgaa
     9061 aaaggtatac tataaagcga gaaaagtttt gaaaaaggag agacggatac catgaagata
     9121 gttgttttgg cagggggact cagcacagag agagacgtgt ccttcaagac aggagagatg
     9181 gttacgaaag cactcagaga gaacggacat caggtaattt tacttgatgt ttttatggga
     9241 tatagcgata aggaagaaga tcttaccgga atttttgaca gagccgaggc ggtcagcgtc
     9301 aaggtggcgg cgattccgga gaccgcgccg aacctggaaa aagtaaaggc gcagagaaag
     9361 gatcagtcgg ataatttctt cggaccgaat gtcatagagc tttgccggat ggcggacatc
     9421 gtgtttatgg cgcttcatgg agagaacgga gagaacggta agatccaggc ggcgtttgac
     9481 ctgttcggca tccgctacac aggaaccgga tatctgggca gtgcgcttgc catgaacaaa
     9541 ggaatggcaa agcagctgtt cctcgagaat ggaatcccga cgccgagagg cacgtcctta
     9601 aagcgcggcg aggatgcggc aaagatcgag acctgtggaa ttcatttccc atgcgtggta
     9661 aagccatgca gcggcggatc aagcatcggc gtatcgatcg tgcacgacaa ggcggaatac
     9721 gagcaggcat taaaggaggc gttccgctgg gagaatgagc tggtcattga ggaatatgta
     9781 aaaggaagag aattttctgt cggcgtcatt gattttcagg cgcttccgat catcgagatc
     9841 gcgccggtgg aaggcttcta tgattataag aacaaataca aagcgggaag tacggtagag
     9901 acctgcccgg cggagctgtc cgagcagatt acgaaggaaa tgcagggata tgcagagaag
     9961 gtggcagagg tgcttgggct caatacatac tcgcgcacag acttccttct ggatgcggaa
    10021 gatcacattt tctgtctgga ggcgaacaca cttccgggca tgacgccgac cagcctgctg
    10081 ccgcaggagg caaaggtgac cggcgtggat ttcaaccagc tctgcgagaa gctgatcgag
    10141 agttccatgc gcaaatataa gaattaagag tgaagtctga aatgggagcc attatgaaaa
    10201 atatgacatt ggagcatatc gcgcaggcat gtggcggtac atacatcggg gaagaatgcg
    10261 accgcaaaaa ggagattcag ggggcggtga ttgacagccg tctggtcggg gagggatatc
    10321 tgtttattcc tatccgcgga gcgcgcgttg acgggcatga tttcattccg gcggtttttg
    10381 aaaagggagc gcttgccgtg ctctccgaac agcggctcga gcatccggca ggaccgtata
    10441 ttctggttga ctccacggag gaagccatga agaagatcgc ggcgttctac cgccgctcgc
    10501 tcgacatcaa agtcgtgggg atcacaggaa gcgttggaaa gaccagcaca aaagagatga
    10561 ttgcgtcggt gctctccgag aaataccgcg tgttaaagac cgaggggaat ctgaacaatg
    10621 agatcgggct tccgctgacg atctttaaga tccgggagga acatcaggtg gcggtgctcg
    10681 agatgggaat ctctgagttc ggtgagatgc accgtcttgc agagatggca cagccggata
    10741 tctgcgtcat taccaatatc ggcttatgtc atctggagaa cctcatcaca agagacggca
    10801 ttttaaaggc gaagacggag agctttgagc atctggcacc ggacgggatc gccgtattaa
    10861 acggggatga cgataagctc tgtgacaaaa agatggtgaa tggcagaccg gcggtgttct
    10921 atggaatcgg acaggaagca aagacggcag agacagagac cggcagcaaa cggctcgcgg
    10981 aaaaggaagt gtacgcgacc gatgtggagg cgatcggact tgagggaacg aaggcggtca
    11041 ttcacacgcc ggagcagcag tttgaggtgg tgatcccgat tgctggtgag cacaatgtat
    11101 acaacgcgct tgcagcagtc tgcgtggcaa gacggctggg acttgatgcg gaggagatga
    11161 agcttggaat tgagcatgcg cacacgattg gcgggcggag taatctgatc cggaagaacg
    11221 gcatcacaat tatcgacgac tgctacaatg cgaatccggt gtccatgatg gcttccatag
    11281 acgtgctgtc ccaggcgaag ggacgaaaga ttgccgtgct cggcgatatg ggagaactcg
    11341 gcagtgagga aaagaagctg cacggaatgg tcggcacaca ctttgcgggg aagaagatcg
    11401 atgcgctgtt tgtgaccgga acacttgcag gggagattgc ggaggaggcg cggcgtgtag
    11461 cgccggagac cagggtctat gcggaaccgg acaaagaggc gctggaggag gcgctgctgg
    11521 agtaccgcag accgggagat accattctgg taaaggcgtc ccattttatg ggattttcgg
    11581 agattgtgaa aaaattggaa cagccacagt gaataaggaa ggtacacatg aaaaagaata
    11641 tcatactgat aggaatgccc ggcgtcggaa agagtaccgt tggcgtggtt cttgcaaaag
    11701 tgatgggata ccagttcatt gatgccgatc tggtgataca ggaaaaggaa ggaaagcttc
    11761 tgcgtgagat tatcgctgaa gtcggaccgg agggattcct taaggtggag aaccgcatca
    11821 acagcgggat cgaggcggaa catgccatta ttgcaaccgg cgggagcgtg gtgtacggag
    11881 cggaagcgat ggaacacctt ggccggatcg gtacggtggt ttatctgaaa cttccgtacc
    11941 gggaattgga gcgcaggctc tcggacatca agggaagagg ggttgtctta agagacggac
    12001 agacacttca tgatctctat gaggaacgtg tgcctttgta cgagaaatat gcggatgtga
    12061 ttgtggatga acatcatttg aacgtggaac agacgattga gaaaattatg gaattgaagg
    12121 aacgctttca atgaagaaac aaacgtttac aaaacaggca gtctggcagg cagctgcggt
    12181 aggagtcctg gcggtcggcg gagtcctttt ttgcctttcc gggcagattg gaatcggaca
    12241 gacataccgg caggtgcgcg tggatgaccg catcatcggg tatgcgccgg agaacactga
    12301 tatggatgac atcgtccgtc aggcgagaca ggaactgacg caaaagaccg gggagagaat
    12361 cagcggcgaa gtcgtatgga gcagtgagga gtgcagaaaa ccgttccaga agttgttgtc
    12421 ggagaatgaa ttaaaagaag ccgtagagaa catactaagt gagaaaaatg cagaggaaaa
    12481 gcagcgcgtc tatacagtgg cgatcgatga ataccgcgcc aactttgcga cgatggacga
    12541 ggtggagtct tttctggaaa aagtgaaggc ttctgcggat gcggcggatg aatacggggc
    12601 ggtcattgcg gatcagggct cccatgtgag cggaattctg acagcgtctc ttgccagaag
    12661 ggacgcaggg gctgcagcgg atgaaaaggt gctggaggaa gcacaggctt ctctgccgca
    12721 ggcaggaatc agcgcctatg tgatctgtac gctggaggag gcatttgcag atccaaaagc
    12781 cacgtatgag acaggcatcc ttgatatgga atttgtggag cgggtgaatg tgttcgagaa
    12841 ctatgtcgat gccaatcaga ttgcagatgt ggatgaacag gttgccgaag taacaaaaga
    12901 gaaagaatcg aataaaatat atgtagtgga gagcggagac tgtctctccg tgattgcgat
    12961 ggatcatgat acgacagtgt cgtcgatcgt ggcgttaaac gggctggaca gcgcggatgc
    13021 gatgataagg gacggtcagg aactcatcat tgcggtgccg gagccggatc tgcagcttcg
    13081 ggtaacaaaa ggagaggtct atgaggagga ctacacggaa gagccgatca tcatagacaa
    13141 cgattcctgg tatacgacaa aagaggttgt acagcaggag ggaacgacgg gacaccggga
    13201 gcgcaatgac gttgtggtct atgagaacgg tgtggaaaca agccgcgaga tgatacatca
    13261 gaacgttatg gtggcgtcac aggcggcagt cattgagcgc ggtaccatca ttccgccgac
    13321 ctatatcaaa ccgatttccg gaggaagata tacgtcagga tttggcagac gctggggacg
    13381 tatgcacaag ggcgttgact gggcatgccc gatcgggacg acggtgtacg catcctgtgc
    13441 cggaacggta atctctgcgt cctataatgg cggctacggc aataacgtgg tcatcagcca
    13501 tgcggatggc agactgacga gatatgcaca caacagtaag cttctggtga aggctggaca
    13561 gcatgttgag cagggagagc cgatcgcgtt aagtggaagt acgggacgtt ctacaggacc
    13621 gcatgttcat tttgagatct atatcaacgg ttcagcagtg gatccgctca aatacatcag
    13681 caactgatgg gaagaggaca cagactggaa atagttgtat gctgtacaaa tggatgaaat
    13741 ttatggtata atgtacacta tatggttgat gaacgaagaa cttaagaatt acttgacaaa
    13801 agcatgtaag cactagtata attacgtgtt tgtataaagc gttcatagag gtgtgatatg
    13861 gaacagtatg tgatcaaagg tggaaatccg ctggtaggag aagtggaaat cggaggcgct
    13921 aagaatgcgg cgcttgcgat cttatctgct gcagttatga cggatgagac cgttacaata
    13981 gaaaatgtac ctaatgtcag agataccaac gttttactca atgccatcga ggagattgga
    14041 gcgcgggtag agcggctgga tgctcacacg gtaaggatca atggatcttt tatccgggat
    14101 tttaatgttg acaatgaatt tatccgaaaa atacgcgcat cttattatct gatcggcgca
    14161 ctgctcggca aatataagcg ggcggaagtg gcgcttccgg gcggatgcaa catcggcgga
    14221 cggccgatcg atctgcacat gaagggcttt agggctctgg gggctgatgt ggatatcaag
    14281 tatggtctgg tgcgggctta tgcagaaaag ttaaccggca cgcacattta tctggataag
    14341 gtgtctgtcg gggcaaccat caatattatg atggcggcgt ccatggcaga gggcaagacg
    14401 attatcgaga atgcggcgaa ggagccgcat gtggttgacg ttgctaactt cttaaacagc
    14461 atgggagcca atatccgcgg tgccggtacg gacgtgatcc ggattgtcgg agtggagaag
    14521 ctgcatgcga cagagtattc gattattccg gatcagatcg aggcaggcac ctttatgctg
    14581 gcggcagcgg cgaccaaggg cgacgttacc gtgaaaaatg tgatcccgaa acatctggaa
    14641 gcgatcagcg caaagctgct tgagatcggg tgcgaggtgg aggagttcga tgacgctgtg
    14701 cgcgtggtgg catcgaagcc gctgcgtcat acacaggtga cgacgcttcc ttacccgggc
    14761 ttcccgacgg atatgcagcc gcagatgacg gttgtgctgg gagtggccca gggaacgagt
    14821 accgtgacgg agagcatttt cgagaatcgt tttaagtatg tggatgagtt gacacgcatg
    14881 ggtgcaagca tcaaggtgga gagcaacatc gctattatca gcggtgtgga ccagtacacc
    14941 ggtgccagag tcaatgcgcc ggatttaaga gccggagcgg cgcttgtgat tgccggactt
    15001 ggcgcagagg gcattactgt tgtggacgat atttattaca ttgagcgcgg ctacgaggca
    15061 tttgatcaga agctgtcact gcttggggca ttgattgaga aagtttccga cgaaaaagag
    15121 atacagaagt ttacactgaa agtatcatag aatggaagtt ttgaaccatc aggtctgctg
    15181 cgggagggga tcccacagca gacatttttt atttcatagg aaatactgcg gcacgttaat
    15241 acaagaaagc agaaccttcc tatgaaataa aaaaacggtc ttttgatatg atagcgcgga
    15301 agacagactt ggaggataac aatggaagca caggaaatac aacagaaaga gttacatact
    15361 gtgagaggag aactggcact gcttgttgca gtgctgatta acagcttcgg ggtggtgctg
    15421 atgctgcact ccggcgcggg aatctctgcc atctcgagcg tgccgttcgc gttttcggaa
    15481 gtgtttacgc ggatctcgct cggcacatgg acctacctgt tccagggcgt cc
//
