LOCUS       gnlProkkaFPGOFBJB_4    28878 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FPGOFBJB_4.
ACCESSION   gnlProkkaFPGOFBJB_4
VERSION     gnlProkkaFPGOFBJB_4
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 07:59:46
            Original ID  :: gnl|Prokka|FPGOFBJB_4
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 110049
            Orig. end    :: 138927
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..28878
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:23878]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..23878
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..28878
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..28878
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             890..1801
                     /locus_tag="ctg4_88"
                     /transl_table=11
                     /translation="MLEFPENYFRGEELEGFYVEEMMKRAWAAQIKVLKEIERICQKRG
                     ITYFADYGTLLGAVRHKGFIPWDDDIDIAMKPTDYKRFLQIAEQELPEGWKLLSLYNND
                     EYTETFARVVNSDRINNYKEWLDEWFGCPFVVGVDIFPLNYMPLDEDEAEIQKELYIIV
                     KNARAVCQEHTEEAEQLLKLVEEVCRVTLDRSGNLERQLSMLLERIRIMYDAEEQGELT
                     QIEVFSRKSFCRIPQEAYEKSIPMMFEGTDVQVPVGWDTVLRAEYGDDYMTPIQVRSSA
                     CHDYPFYKKQMKILEERSKGKQ"
     CDS             complement(1839..3860)
                     /locus_tag="ctg4_89"
                     /transl_table=11
                     /translation="MKQKLEQAILQQDIPEIEACLTRYEACNPTDFDLFSYKISLALLK
                     EDLQAAYDFAKTAITLNPFDVEANYNFMVCARSLGKYAVAYQSFLMIQFVQMRYQITVI
                     DDETLAVWEQEFQILAAEDTDLENEFSRIEQNHRYAILDPFKNYQESLCGKILTCYNRQ
                     QYYIGLADNWYESYFNFSFIKDPIHAKCELFPIADISTKYDIPADLGKVLVPICLNYDL
                     TQKNSNYITDAAKDPTKFYRESAREKYCYLPVENGTALRTAYPAVFGTPIPLTHPDANG
                     RKKLVLSIFIDSFNYYLVKDLGLETLMPETFRYFSKGIICNNYYSGSEWTLPSIATYWT
                     GKHSSHHMNLMENYRFDFMKDSKVLAEYFHDAGYVTAKIGGNDAVTPWQGYIRGIDRFT
                     YQYSSQAYRTKEVISDVIQQIETFKDACQYIWFDFLDLHDIAGGFMCSLPVQSRLPLAA
                     RHIDNNITTTVKQSFSPNRREIYIQQLRELDFYLGILYQYLERNYKDEEIIVSLFSDHG
                     TAFMVEDGKPFLSEQRVNVPFMLRCSNLSPRISDELIETADYTAILCKLAGIPYHFEGT
                     DANLPLTFGGKQERDYTFSQNIFPGDPYRAALHGKDFHFYMDSTIPVSPNLRIDLTNRK
                     CILTDANGQPVQNEALIKKYETIIKKEIAHLLIYPFNN"
     CDS             complement(3885..4868)
                     /locus_tag="ctg4_90"
                     /transl_table=11
                     /translation="MNFPAEFFQDEYRCDFLVPELMKRAWAAEIEILEVVSQICEKYSL
                     QYFAYYGTLLGAVRHQGFVPWDDDIDICLKRSDYNTLVSVLPDELPAGFIAGGLHATVN
                     TLVLQTDVIHTAVGTDPSYWSLAEHIKRFHGFPFRGTSIDIFPLDYIPRDTDTFLLEKL
                     LLGRIFALLHDFDTLPEDTKEARIVELEELTATKLPRNETTKWSLFHLLEAIASMFDES
                     ECDELDLCFRIPYENKDPLKKEWYNETIYLPFEGFQIAAPKHYHEILTTYYGDYQVPVK
                     FTQSHEYPFYKKSEQELTAILTQKGFQGSICDFIHNIDSFHILESK"
     CDS             5001..6803
                     /NRPS_PKS="Domain: Aminotran_1_2 (316-595). E-value:
                     1.2e-32. Score: 105.3. Matches aSDomain:
                     nrpspksdomains_ctg4_91_Aminotran_1_2.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 97.5; E-value: 1.4e-29)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_91"
                     /sec_met_domain="NTP_transf_3 (E-value: 4.2e-14, bitscore:
                     46.1, seeds: 297, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.6e-32, bitscore:
                     105.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQAIILAAGMGKRLGQLTKDNTKCMVEVGGVRLVERVLRILDKKG
                     LSRIIMVVGYQHENLMTFVNELGIRTPIEFIINDVYDKTNNIFSLALAKEQLGSEDTLL
                     LESDLIFEESVIDLLLEDERDTLVLVDKFENWMDGTCVVVDEEDNILDFIPGKLLKYSE
                     KAHYYKTVNIYKLSADFSRNVYVPFLEAYAKVMGNNEYYETVIKLILTLDKNTMKAKRL
                     HGEQWYEIDDIQDLDIAELLFLEDDVERYHTLTSRYGGFWRFPHLKDYCYLVNPYFPTE
                     RMMNEMKSNFDVLVRQYPSGMRVNSLLAAKSFSVSEEHIVIGNGAAELIKELLTELEGT
                     VGVISPTFEEYPHRCNGRYVVYDSREHDFSYDVDSLCSYFTEHPVSSMVLINPDNPSGH
                     YLDKKEIRKLLDWCKSNGTALILDESFLDFADDTSASMLSERMMKKYPKLYLVKSISKS
                     YGVPGLRLGILASYDEKMIAVLKKKVAIWNINSLGEFFMQILDKYKADYKQSLVWLREE
                     RALFYQELCKIKGLKVYPSAANYFMCELTNGKRSEALAAELLKDNILIKDLSGKIDNGK
                     QYIRIAIRDREDNEKLQRALAKRL"
     aSDomain        5949..6785
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_91_Aminotran_1_2.1"
                     /evalue="1.20E-32"
                     /label="ctg4_91_Aminotran_1_2.1"
                     /locus_tag="ctg4_91"
                     /protein_end="595"
                     /protein_start="316"
                     /score="105.3"
                     /tool="antismash"
                     /translation="EEHIVIGNGAAELIKELLTELEGTVGVISPTFEEYPHRCNGRYVV
                     YDSREHDFSYDVDSLCSYFTEHPVSSMVLINPDNPSGHYLDKKEIRKLLDWCKSNGTAL
                     ILDESFLDFADDTSASMLSERMMKKYPKLYLVKSISKSYGVPGLRLGILASYDEKMIAV
                     LKKKVAIWNINSLGEFFMQILDKYKADYKQSLVWLREERALFYQELCKIKGLKVYPSAA
                     NYFMCELTNGKRSEALAAELLKDNILIKDLSGKIDNGKQYIRIAIRDREDNEKLQRA"
     CDS             6831..8021
                     /locus_tag="ctg4_92"
                     /transl_table=11
                     /translation="MNVAFIPVRGGSKSIPLKNIKPMCGKPLVYWTVAAACGCAKIDKV
                     YVATDSEKIRETLLEVKQQEKNEAFQKLEVIGRSAESASDTASTEFAMLEFANEHAFDH
                     IVLIQATSPLLTAEDLDRGFALYEEADTDSVLSVVRQKRFNWKVAKDGTAQALNYDYFH
                     RPRRQEFDGYCVENGAFYITSKERLCETGNRISGKVKAVEMSEDTFFEIDEPSDWQIIE
                     KMLERRLHGAQEKTDQDEKKAIKMFLTDCDGCLTDGGMYYSENGDELKKFSTLDGLGMR
                     LMREKGILCGIVTGENTKLVARRAEKLHLDILKMGIKDKLSVVKELCGQYGISLQEVAY
                     VGDDINDKELLAAVGFSASVPGAMDEVKEIVAYVTKRQGGSGAVREVIECILSGRK"
     CDS             8116..8478
                     /locus_tag="ctg4_93"
                     /transl_table=11
                     /translation="MEESRTEKLEALETLVSYNDKVVKNVGILIKELSGQRLDDTDKFL
                     DSILNAINWEIQVLNATMDVINKGKERIIKEAFNEKVIALGEAVKGKDDAKMADAFRAL
                     EPELEKLGAAAREVIG"
     CDS             8564..9277
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Metallophos_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_94"
                     /sec_met_domain="Metallophos_2 (E-value: 1.7e-23, bitscore:
                     76.4, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDIHGNLSALNKIWKTEEIEEFEGIVLLGDLIDYGPHSNEVVEK
                     LKCLPKHKILVNIWGNHEKAVVDGDDSRFSSERGKKCAAHTRKTLTKQTMQYLENEMDE
                     SGHMEFELAGKKCLAVHGSADDFFWKSISHGEDQDEYKKYDYVFSGHSHIPHYFEHFYP
                     AECKEYRNREKTVFLNPGSVGQPRNHNANAQYAILEPETMSVQMKAVSYDIEQEIAAFS
                     DEVDSFYKERLRIGV"
     CDS             9280..10575
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 210.2;
                     E-value: 6e-64)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_95"
                     /sec_met_domain="CTP_transf_like (E-value: 7.6e-14,
                     bitscore: 45.1, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 3.2e-109, bitscore:
                     357.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 7.9e-64, bitscore:
                     208.3, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVYLCMSTDIIQTGHINVIEKAAELGEVTVGVLSDKYVAMYEK
                     YPILPLEERMRIIQNIKGVSKVVVQNDIYYDETIRELKPDIVIHGDNWTDGYQKAVRDR
                     VIEVLAEWGGELIEIPYYKSSNLHLFENAMSESRGLPEVRRQVLRRKICSGEVFKVMVA
                     YDGLSALLVEKTSIEKDGERRQFDGIWISSLCDSTAKGKPDIELVDLTSRLNSVNDIME
                     VTTKPIIFDADTGGLVEHFVYNIKTLERMGVSAVIIEDKIGLKRNSLLGNDVEQHQDSI
                     EHFCEKIREGKKAIGSSAFMLIARIESLILDQGVDDALERAKAYVEAGADGIMIHSRAK
                     SPDEIFEFADRFRETDKDTAIVVVPTTYNQVRESEFKEHKINVVIYANHMLRAAFPAMQ
                     KVVTSVLENERCYEASQDCMSIKDILSLVPVE"
     CDS             10603..11604
                     /NRPS_PKS="Domain: NAD_binding_4 (48-224). E-value:
                     1.5e-10. Score: 32.5. Matches aSDomain:
                     nrpspksdomains_ctg4_96_NAD_binding_4.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     153.7; E-value: 1.2e-46)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_96"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 3.2e-07,
                     bitscore: 22.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.8e-09, bitscore:
                     29.0, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLYVISGMTGMTGNELARQIVKRGDDVIGFDNFFASSTETIKD
                     VIDSEHLEFFEGDINNDAQMKELEEKVTARKAEYEKVTYINCAAVVHTEHFYHVDRTFE
                     TNVIGMKKFLEQAIRVGADSYINCSTSEVYSMASWKEGGVKEDDFLLLATAEHSQRTSY
                     ATGKLLTEFFMKDAVERGMIKGCSLRFANVYSKNELLAKHVIPHVITSLMKDGKVTLLE
                     NSKVNKRTFLHNIDSCAAVLAVADTDAALDGTVYNVATEQEVSMIELVDVCAKAIGIEK
                     PEIIFEGYRESDPQRRVLSAAKIKARTRWEPTITLEQGIKMCVDYRRQVEGK"
     aSDomain        10747..11274
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_96_NAD_binding_4.1"
                     /evalue="1.50E-10"
                     /label="ctg4_96_NAD_binding_4.1"
                     /locus_tag="ctg4_96"
                     /protein_end="224"
                     /protein_start="48"
                     /score="32.5"
                     /tool="antismash"
                     /translation="SEHLEFFEGDINNDAQMKELEEKVTARKAEYEKVTYINCAAVVHT
                     EHFYHVDRTFETNVIGMKKFLEQAIRVGADSYINCSTSEVYSMASWKEGGVKEDDFLLL
                     ATAEHSQRTSYATGKLLTEFFMKDAVERGMIKGCSLRFANVYSKNELLAKHVIPHVITS
                     LMKDGKVTLLENS"
     CDS             11605..12351
                     /locus_tag="ctg4_97"
                     /transl_table=11
                     /translation="MKTVIVAVAGMSIRFNQDMAEPVLKGIYTEGDVRKTLLYSILRKC
                     KGFDRVVLVGGYQYEKLVEYVSACKEDFPFQIQMVYNSNYQEFGTGYTLKLGLEQCLQD
                     NSSEITLIEGDLFFDEASLDDVKRSTRSVATYNNKTIYSNKAVIAYINEAHELKYKFST
                     NHGSVEIAEPFLAIYNSGQIWKFADTDVVKQLVSDSPETMWQGTNLKFIEEYFHQISEE
                     ERELLPLKTWENCNTKADYLKYEEQL"
     CDS             12363..13544
                     /locus_tag="ctg4_98"
                     /transl_table=11
                     /translation="MNKEESSKKIKVAFFPYKISMWDSLESIWEATDRDESCECQVIPI
                     PYYSKNADGEIEKEHYEGAAFAKKVPIIDYQTYFLEQEMPDVMYIHNPYDQYNKVTMVH
                     PRFFSTELKKGGGILVYVPYYISGFCEKYENMLPVCANMGAVYSDYLILQNENLKNAYA
                     FCGYPERRLLVLGSPKVDAVYKIGEKQFSKIDEWKPVIENRKVILLNTSITTCLTNASW
                     LEQIQKLIEPILQDNRLALIWRPHPLLLDTMRSMLQKQAEYDTLLERIRKAPNAMIDDS
                     DTAEAAMKASDAMISDYSSLVMQYNFTGKPSYILTGKSENRKDCVFCDYFSNYFREDGE
                     DLSDFLNMVLAGIDPKQQERMEYARSSMANTDGTCGEKVHREICKKVMTGANR"
     CDS             13546..14403
                     /locus_tag="ctg4_99"
                     /transl_table=11
                     /translation="MEEIKITEEQRERIRKIQLEMIREVHRICEKNHIKYVLGYGTMLG
                     AVRHKGFIPWDDDADILMLRKDYRRFCEACKKELPEKYFLQDECSDEYYLWGYSKLRNM
                     NTTYVRCGQEHIPYKNGVFIDIFPLDNVPWFLPFRILQDAYGFVLRKMLWAKVGKNTEK
                     NPLVRLVYKILAPIPKSTIYAMRNVMVHKGNKVSDRVRCLLFTAPGKHWNKKANSLYSR
                     YGFKRDWLLDREKYVFEGEEFWGTREYDDCLSYLYGDYMKLPPEEKRVGHAPVSKLELN
                     QEGL"
     CDS             14407..15024
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 58.4; E-value:
                     1.2e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_100"
                     /transl_table=11
                     /translation="MDKSYWDTFYAANKGVNEPSLFARWVLEQVETDKKIVDMGCGNGR
                     DSIYFMENGMQVYAVDASDVATEHIAQVYAGKINVENKDYVSYLGERSEEFDYLYSRFT
                     IHAILEEEQECCIKNAYKALKPGGKFFIEVRCVKDELFGKGTLVAKNTYFYNGHNRRFI
                     EKEELAQQLTETGFQVIYAEEKTGFAPFGDSDPVVLRMVAVK"
     CDS             15092..16276
                     /locus_tag="ctg4_101"
                     /transl_table=11
                     /translation="MKDLETRLQLVKKHIEDNNITVMILGLGSVGTYLLDFLTSRNDAS
                     MKLVVVGRNAEKLENNANIVRISALIRHVNRSQIIIESGVDFDEVGQVAECIKKYQPDF
                     IVNSSRVYSGLKYGSISWKNLRAYGIWSPLAIKYIKNIMKACEIADLNGIVINTSYSDA
                     VIPWLKTAGQPYPDFGSGNMNHLVPRIKYAVAEIKEIPDFWNVDVMFATAHFHDVVISK
                     EGQTEEVPQLLKVFYQGKELDIDQNDIFARCKITMPTDEKRNMMNASSNYDIICSIIDA
                     VRESDSRKIFSPGVFGEIGGYPVRIDATGDKLQAYIDESVFTLEQMREANRKSIALDGV
                     ENVEDGSLTYTDDLVRKVADVFDVRLPKTVAFEEIDQTAAYIIDNIIVPQLNKK"
     CDS             16291..17427
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 55;
                     E-value: 9.8e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_102"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.3e-21, bitscore:
                     68.6, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.8e-18, bitscore:
                     58.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVESFVEEIRSLGIETIAGVPDSALQPLCYYLNAGECGFHHFVP
                     ANEGAAVGIAIGNYLSTGKPACVYMQNSGIGNIVNPVTSLANKAVYDIPILFVVGWRGE
                     PGKKDEPQHRFMGEITTGILDVLDIPNAILSAEMTEQEIKNIFKNAKEALSENKQFAII
                     VKRDALEAGVKNAYQNDYTLCREDAISEIIKEVDANDVIVSTTGKISREVYEQCDKQLG
                     HHKQAFLTVGGMGHAGMIAYGIAQNRTDKKVYCIEGDGAVLMHMGELAFLAKQQPKNFI
                     HICLNNEAHESVGGMPTGAVGIDFYKTARECGYSYVASVDNLEDLQKQLQYIAGIEGPV
                     FLEVKVKIGARADLGRPKESAVENKENFMKYHFPEVVD"
     CDS             complement(17443..18633)
                     /gene_functions="other (smcogs) SMCOG1229:transposase
                     (Score: 300.2; E-value: 2.9e-91)"
                     /gene_kind="other"
                     /locus_tag="ctg4_103"
                     /transl_table=11
                     /translation="MGRKVNTITLTEEQRSYLELQTRARTIQAQTVCRARILLLRADGV
                     SINDIADKVGINRCSVMLCLNKFKEGGVENALFDAPGRGRNAEITDDEKTWIINIACQK
                     PVNLGYSAEVWTRALLTKHINKFAENAGYTRLSTISQSKVRTILEEADIKPDKITYYCE
                     NRDPDFDQKMHNVLLVYKQLSLQFDKKGQLLPFCEDDQVVHVLSYDEKPGIQAIATTSE
                     DIQPDNNHKTISRDYEYRRLGTISLLAGIDLQTGEAIPLVKESHNSKDYIEFLKKLDNK
                     YPKSDKIRLVLDNLKVHSSEETRKYLATVPGRFEFVFTPKHGSWLNLVEGFFSKLTRQM
                     LKGIRVKTKDELVQRIYKYFDEVNEEPVIYHWKYKLEEIDPNEEVVVDTLPVKKSS"
     CDS             18731..19714
                     /locus_tag="ctg4_104"
                     /transl_table=11
                     /translation="MEFPEDFFKKECRCGFEVPEMMKRAWAAQMEVLEVVGKVCEKHHL
                     QYYADWGTLLGAIRHKGFIPWDDDIDICLRRKDYNELIRVLPKGLPHGFVVAGMYAASE
                     RLQNAAYVPQLRVIADETLWDFNSYMRRFHGFPYQRVGIDIFPMDRMPEDLETAKLQKE
                     VIRQGIAILREWDRLQESGQLQGYLKGYGELCNVEIPQRDDLKNWMWRLIDALCSLYQD
                     DDTEFITNWNVWMAKPRLYRVKNEWFDEMRYVPFEHVRIPVPGNYDEVLKAQFGDYMTP
                     SQVKGGHDYPFYAEMEKELVKQIRAVGFMGSVEEFCEKVSTGELQV"
     CDS             complement(19720..20682)
                     /locus_tag="ctg4_105"
                     /transl_table=11
                     /translation="MIFPENFFQDEYRNGFLVPQMMKRAWAAKLELLQIIIDICNKYDI
                     TYFAEYGTLLGAIRHKGFIPWDDDVDIALKRPDYNKLIRVLPSELPNGIALAGPYAQTD
                     KLFLPTCQSVVATVSSDWKLSDYMQRFHGFPYRNMGIDIFPLDYLPDDPELSSLQQYLV
                     QKIVFCVRNWEKTNEITREENVKEIESLCSTHIARDANILRTLIQLSDSIRALYQENDG
                     NDIAKDGFWFTNDRQIATPKEWFAEAITVPFENIMVTVPKQYDEILTNRYGDYRNPVIT
                     VQTHTYPFYKTEEHALRNYLDAHGYTGSIDDFVRKHYSE"
     CDS             20895..21731
                     /locus_tag="ctg4_106"
                     /transl_table=11
                     /translation="MGRIVVNHNMQSMYQHRQLKINTENVDKSSEKLASGYKINHANDE
                     AAELTVSEAMRNQIRGLNKASNNIQDGIGLVQTADAALEETQTILDRMVELTTQAANDV
                     NTEEDRKAIQDEIDQLNKEIDHIAYDTNFNQNYMLAEGTPKAKPGFFYVQTGSLAEQSI
                     IINFVNASKESLGVDKVDVSNHEKASESITMVQDAIEKAAGWRDDFGAVWEQLARAVKN
                     ADYTSQNTQQSESNIRDTDIGDEILGYTTNQILVNASQSLLAQYNSSKDAVLVLLR"
     CDS             22070..23878
                     /NRPS_PKS="Domain: Aminotran_1_2 (317-596). E-value: 1e-30.
                     Score: 98.9. Matches aSDomain:
                     nrpspksdomains_ctg4_107_Aminotran_1_2.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 61.9; E-value:
                     8.7e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_107"
                     /sec_met_domain="NTP_transf_3 (E-value: 7.7e-13, bitscore:
                     42.0, seeds: 297, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.1e-30, bitscore:
                     99.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQAIILAAGMGKRLGELTKNNTKCMVEVGGVRLIERALRILDRKK
                     LSRIILVVGYQHKNLVSFVDSLCLKTPVEYIVNDVYHKTNNIFSLSLAKDQMMQEDTLL
                     LESDLIFEENLIDMLLEDDRDTLALVDKFENWMDGTCIVVDQDDNITDFIPGKLLKYHE
                     KEHYYKTVNIYKFGAQFSRDVYVPFLEAYAKVMGNNEYYETVIKLILMLDKNTMKAKRL
                     NGELWYEIDDIQDLDIAQTLFIEDDVERYHHLMQRYGGYWRFPHLQDYCYLVNPYFPTK
                     RMQEEMESNFDVLVRQYPSGMTVNTLLAAKSFDVHEEHIVIGNGAAELIKGLLEELNGK
                     LGVIRPTFEEYPNRWEKDVIAYDCTENDFSYTDSQLIQYFTENPVDTLVFINPDNPTGH
                     CMDADGIKSLLQWSKECGINLIVDESFLDFADTEDLSLLSEQVLKENRNLYVVKSISKS
                     YGVPGLRLGILASGNTDMIEHLKKDVSIWNINSMAEFFMQILDKYKSDYTDSLRKIKEE
                     RSRFFDELCMIENLKVYPSQANYFMCEILDGMSSEALAGRLLKKNILIKDLTGKIHNGK
                     HYIRLAVRGEEENRRLVEKLKVCMKQ"
     aSDomain        23021..23857
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_107_Aminotran_1_2.1"
                     /evalue="1.00E-30"
                     /label="ctg4_107_Aminotran_1_2.1"
                     /locus_tag="ctg4_107"
                     /protein_end="596"
                     /protein_start="317"
                     /score="98.9"
                     /tool="antismash"
                     /translation="EHIVIGNGAAELIKGLLEELNGKLGVIRPTFEEYPNRWEKDVIAY
                     DCTENDFSYTDSQLIQYFTENPVDTLVFINPDNPTGHCMDADGIKSLLQWSKECGINLI
                     VDESFLDFADTEDLSLLSEQVLKENRNLYVVKSISKSYGVPGLRLGILASGNTDMIEHL
                     KKDVSIWNINSMAEFFMQILDKYKSDYTDSLRKIKEERSRFFDELCMIENLKVYPSQAN
                     YFMCEILDGMSSEALAGRLLKKNILIKDLTGKIHNGKHYIRLAVRGEEENRRLVEKL"
     CDS             24123..24377
                     /locus_tag="ctg4_108"
                     /transl_table=11
                     /translation="MANEIVIVISFIFTIAAMCKVWNLYAMKKYSESKEERLGLTYGFY
                     VDNMQFVEIEGIGNDENGDFDIAKAIKKIEMPDDVRIKA"
     CDS             24377..24841
                     /locus_tag="ctg4_109"
                     /transl_table=11
                     /translation="MNKIDFLEFYNGVVKKLGVHLENEYRQFRFCDNPDSLYEEYLNQK
                     TILRVLYQKKNGESKTLLDRHKVCACMTAAIIKVRLVSGNIQTDDSFSLSVASRINEQL
                     AFMSTWELFLGFIRLHKEETDKKRWAYQMLDDLVCFFYNRECLTAAPNTP"
     CDS             complement(24816..25829)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_110"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-33,
                     bitscore: 109.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVSVIIPCFNATKYLPKCFMSLVQQTIGIDQIELIFVDDASTD
                     EDATWNMLQEFERAYPESIMILKLEENMRQGGARNVALQYATGEYIAFVDADDFVSENF
                     LLETYEKAKESDADIIQFEYFYYTDRLGAVDSGRNITPEVIEISSVSDRKRFLISEKVT
                     YGCWNKLYRHTLLNEAHTAYAEHVIYEEPLFVYPLLYFANKIVILNDAYYYYRQNDSGT
                     MRNDMRQEETLKMHADVQLAVWNFMKKTPFFKEYYDEIKLYFLHTYLYETLYFAKLRDF
                     KPSYAFYKELEKTVLAEVPDYAQSIYSALIPKQMELYRMIGEGMTEVKFKEYWEQL"
     CDS             25950..27662
                     /locus_tag="ctg4_111"
                     /transl_table=11
                     /translation="MSGNIAIGIQDFSTIIQGNYFYIDKTPFIKEWWDCGDSATLITRP
                     HRFGKTLTMSMVEQFFSIDYAGRSDLFEHLAIWKEEKYRELQGTYPVISLSFARIKERD
                     YEKTKQKMCEVLRNIYIKFCYIKDSEKLTDADRAYYERMLEENIKETDATSSLYQLSDF
                     LYRYYGKKVIILLDEYDTPMQEAFVDGYWDELVAFTRSLFNSTFKTNPALERGIMTGIT
                     RVSKESVFSDLNNLKIVTTTSNEYASVFGFTEKEVFDALEQYGLEKEKKEVKRWYDGFI
                     FGEHKDIYNPWSILNYLDTQLYKTFWANTSANSLVGKLIQEGNRTIKEKFEKLLCGEYI
                     WSEIEEQIVYNQLNGNEKAVWSLLLASGYLKVLSYETYQDIEEGKMPKYQLALTNLEVK
                     LMFQGMVHDWFAPVQPDYNDFVRAMLLGDVDAMNEYMNRIAIQTFSYFDTGERASGAEP
                     ERFYHGFVLGLLVDLRDRYYLKSNRESGFGRYDVMLEPKNSKECKAVILEFKVRNPRKE
                     KSIQETVLSALKQICEKKYDADLLDKGIRKEQIYHYGFAFEGKKVLIGTDREE"
     CDS             27665..28858
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_112"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.9e-20,
                     bitscore: 65.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTNIAIGTQENNHMLSVCIITKNEEHNLARCLKSFQNTGFELVV
                     VDTGSTDQTKKIAAEYTENIYDFPWCDDFSAAKNFAVSKAAHPYVMVIDSDEYLQQIDR
                     VQLEKMIAEHPGEVGRIRRINIISGKDGKQENKEWINRIFAKESFHYTGRIHEQVTACD
                     EKEYRTYEAPVVIGHTGYDLPKKEKKAKALRNIRLLEQELKNSGWDEKVHATQLDQNIA
                     KQDTDAEQKSKITDAKKEQQIPYLLYQLGKSYYMAEDYNEACFWFAHGLSYDLEPKLEY
                     VIDMVETYGYALINSGRAGEALFFENIYEEFGNSADFQFLMGLIYMNNAMFDAAVGEFL
                     KAVKHRDCRMAGVNSYAAYYNVGVIYECLEKISEAKYYYQKCGNYEPAKKRLKLINS"
ORIGIN
        1 ggggttggat tatgtgtgta taatttggtg tcaaaacgct cggacacggc ttttaacagg
       61 ttctgccgct cgatcgacgt gatctttcgc gcaagaaaat aattggcata gacataggca
      121 tccgattcgg tgccacccgg ctgcgtatgg tattccagag attttttcat ggaggcgata
      181 atgtcagggg ttaaaagctc ttcgataaag aaatagccat ttaccttcat ctgggcatcc
      241 ataatggcgt taatgtaccc tttggtatag tcatccagat ctgtcatacg gtctaaaaaa
      301 ttatgggact cgttatagag tgcgccgaca aaagagacat cactggataa aatggaacgc
      361 ttgtcataag gaagctgcat ggcacccaga cgtgcggtgt ttgcacacag aggcagataa
      421 tatatggtcg tgatcccctc tttggcaaaa tcaaggtaaa gagctttgtc aaagagaaag
      481 atatagttac atgggttgat cagcgtgtac gaatacaggg aaaccaacgg actgtcatac
      541 acaaaggaca gatattttaa gtgattgcgg ttgcagccgt ttgagatgga tggatagtag
      601 ttgagcgaga aaacaaagga aatctgtttg tcgccagcca gttcgtcaaa ataagtatca
      661 aattctttgc tgttgtaatc ctgtaactgt ttatgatcaa ataattgtac ttcatatccc
      721 acctgtttta gggcatcaat cagatccagc ttgccgaagg agggactgtc taaaaaaagc
      781 actttcataa gtatgtgaga ctcctttttt attctgattg taacatttta acagaaatgg
      841 tacaatcaat aatataaatt atactggatg aaagtacgag gggaaagata tgttagaatt
      901 tccggaaaat tatttcaggg gtgaagagct ggaaggcttt tatgtagaag agatgatgaa
      961 acgcgcctgg gctgcacaga taaaagttct gaaagaaata gaacgtatct gccagaagcg
     1021 gggaattacc tattttgcag attatggaac acttcttggc gcggtgcgcc ataaaggatt
     1081 tattccgtgg gatgatgata ttgacattgc catgaaaccg acagattaca aacggttttt
     1141 acagatagca gaacaggaac tgcccgaggg ctggaaactg ctctcgcttt ataataatga
     1201 tgagtataca gagacatttg cacgtgtcgt aaattctgac cgcattaaca attataagga
     1261 atggttagac gaatggtttg gctgtccgtt tgtggtaggc gtggatattt ttccattaaa
     1321 ttatatgcca cttgatgagg atgaggcaga gatacagaaa gaactgtata ttatcgtaaa
     1381 aaatgcgaga gcggtatgtc aggagcatac agaggaagca gaacagttat tgaagctggt
     1441 ggaagaggtg tgcagagtaa ccttagaccg ttcgggcaat ttggagagac agttaagtat
     1501 gctgttggag cggatccgca ttatgtatga tgcagaggag cagggtgaac ttacccagat
     1561 cgaagttttt tcaagaaaaa gtttctgccg gattccacag gaagcgtatg aaaaatcaat
     1621 accgatgatg tttgaaggaa cggatgtgca ggtgccggtt ggctgggata ctgtcttgcg
     1681 ggcagaatat ggagatgatt atatgacacc aatccaggtt cgcagtagtg cgtgccacga
     1741 ttatccgttt tataaaaaac agatgaagat attagaagaa agaagtaaag gaaaacaata
     1801 aaaaaatggg gaatccgttt tgcggattcc ccattttttt agttattgaa tggatagatc
     1861 aaaagatgag cgatctcttt ttttataatg gtttcatatt tttttatgag agcttcattc
     1921 tgaacgggtt gtccattggc atcggtaagt atacatttcc ggttggtcag atcaatgcga
     1981 aggttaggtg ataccggaat tgtggagtcc atataaaaat gaaaatcctt tccatgtaaa
     2041 gcagcgcggt aagggtcacc cgggaaaatg ttctgggaaa acgtatagtc gcgttcctgt
     2101 ttgccaccaa atgtaagggg cagattggca tcggttccct caaagtgata tggaataccg
     2161 gctaatttac acagaatagc agtataatcg gcagtttcta tcagctcgtc cgaaatccga
     2221 ggagaaagat tgctacaacg cagcataaat ggcacattga cacgctgctc ggaaaggaaa
     2281 ggtttcccat cttccaccat gaaagcggtt ccgtggtcgg aaaacagcga gacgatgatc
     2341 tcttcatctt tataattgcg ttccagatac tgatacagga tgccaagata aaaatctaac
     2401 tcgcgtaact gctggatata aatttcccgg cggttagggc taaatgactg ttttaccgtc
     2461 gttgtgatgt tattgtcaat atgtcgtgca gccagtggca atctggactg caccggaaga
     2521 gaacacataa atcccccggc aatatcgtgc agatcaagga agtcaaacca gatatactga
     2581 caggcatcct taaaggtttc gatctgttgg atgacgtcac tgataacttc tttggtgcgg
     2641 tatgcctggg aggaatactg ataggtaaag cggtcaatcc cgcggatgta cccctgccat
     2701 ggggtaaccg catcatttcc accgatcttt gcggtcacat atccggcatc gtgaaaatat
     2761 tctgccagga ctttggagtc tttcataaag tcaaagcgat agttctccat aaggttcatg
     2821 tgatgactgg agtgttttcc agtccagtag gttgcaatgg acggcagagt ccattcggaa
     2881 ccagagtaat aattattaca gataatgcct ttggaaaaat atcggaaagt ttccggcatc
     2941 agtgtttcaa gaccgagatc tttgaccaga taataattaa aactatcgat aaaaatgctt
     3001 aataccagtt tttttcgacc gtttgcatcg gggtgcgtca atggaattgg ggtgccaaaa
     3061 acagcgggat aagccgttcg cagtgcagta ccattttcta cagggagata gcagtatttt
     3121 tctcgtgctg attcccggta gaattttgtt ggatcttttg cagcatccgt aatgtaattg
     3181 gaatttttct gtgtgagatc ataatttagg cagatgggga ccagtacctt gccgaggtct
     3241 gcaggaatgt catattttgt gctgatatcg gcaattggga ataattcaca tttggcatga
     3301 attggatcct tgataaacga aaagttaaag tatgattcgt accagttgtc agcaagccca
     3361 atataatatt gttgtctgtt ataacaggta agtatttttc cacacaggct ttcctgataa
     3421 ttcttaaaag ggtccagtat ggcatagcgg tggttttgct caatacggga aaattcgttc
     3481 tccaagtcag tgtcttctgc agcaagtatt tgaaattcct gttcccatac agccagtgtc
     3541 tcatcgtcga taactgttat ctgatatcgc atctgcacaa actggatcat caggaacgac
     3601 tggtaagcga cggcgtattt cccaagtgat ctggcacaga ccatgaaatt ataattggct
     3661 tctacatcaa atggattgag ggtaattgcc gtttttgcaa aatcgtaggc tgcctggagg
     3721 tcttctttta gcagagccag tgagattttg taagaaaaaa gatcaaagtc ggtgggattg
     3781 caggcttcat aacgtgtcag gcaggcttcg atctctggaa tgtcctgctg taagattgcc
     3841 tgttcaagtt tttgcttcat gggtgggatg tcctcttttc aaaattattt ggattcaaga
     3901 atgtgaaagg aatcaatatt gtggataaaa tcacagatac taccctgaaa gcctttctgc
     3961 gtcagaatgg cagtcagttc ctgttcactt tttttataaa atggatattc gtgtgactgt
     4021 gtaaatttga ccggtacctg atagtctcca tagtaggtag tcaatatttc atggtaatgt
     4081 tttggagcgg cgatctggaa accttcaaaa ggaaggtaga tcgtttcatt ataccattct
     4141 tttttcagag gatctttgtt ttcataggga atacggaaac atagatccag ttcgtcacat
     4201 tcactttcgt caaacatgga agcaatcgcc tcaagaagat gaaataaaga ccatttggtc
     4261 gtctcgtttc gcggcagctt tgtcgcagtg agttcttcca gttccacaat ccgggcttct
     4321 tttgtatctt ccggtaaggt atcaaaatca tgcaaaagtg cgaaaatgcg tccgagcaga
     4381 agtttttcca aaagaaaggt atcagtgtct cttggaatat aatcaagagg aaaaatatca
     4441 atgcttgttc cgcggaacgg aaaaccatga aatcgcttga tatgttctgc gagggaccag
     4501 taggatggat ctgttccaac tgcagtgtga atgacatctg tttgcaggac gagtgtgttg
     4561 actgtggcat gtaaaccacc tgcaataaag ccggccggca attcatctgg taaaacggaa
     4621 accagagtat tatagtcgct tcgttttaag cagatatcga tgtcatcatc ccatggaaca
     4681 aaaccctggt ggcggacagc accgagcagt gtaccataat aagcaaagta ttgcaggctg
     4741 tatttctcac agatctgtga cacgacttcc aaaatctcga tttctgccgc ccaggcgcgt
     4801 ttcatcagct ctggaacaag aaaatcgcag cgatattcat cttgaaaaaa ttcagcagga
     4861 aaattcataa gtattactcc ccaaattgtg ttaatataag atatagtaaa tatatcggca
     4921 aaaatagacg aaacatatat ataatttttg tgaaaaagat taacagaacg gtgatgcgtt
     4981 cagaggcgaa ggagaaaaag atgcaggcga ttattctggc agcaggaatg ggaaaacgtt
     5041 tggggcaatt aaccaaagac aacacaaagt gtatggtaga agtcggtgga gtaagactgg
     5101 tggagcgcgt tttgcgtatc ctcgataaaa agggattatc aaggatcatt atggtggtcg
     5161 ggtaccagca tgaaaatctg atgacgttcg taaatgaact gggtatcagg acaccgatcg
     5221 aatttatcat caatgatgtg tatgacaaga cgaataatat tttttcactg gctctggcga
     5281 aggaacagct tggaagtgaa gatacgcttt tactggagtc cgatctgatc tttgaggaga
     5341 gcgtgatcga tctgctgctt gaggatgaaa gggatacgct ggttctggtg gataagtttg
     5401 aaaactggat ggacggaacc tgtgttgtgg tagatgagga agacaatatt ctggatttca
     5461 ttccaggcaa gctgttaaaa tattcggaga aagcgcatta ttataagacc gtaaacatct
     5521 ataaactcag cgcggatttc tccagaaatg tctatgtccc gtttctggag gcatatgcca
     5581 aggtaatggg aaacaacgaa tattatgaga ccgtgatcaa gctgatcctg actctggata
     5641 aaaacaccat gaaggcaaaa cgtctgcacg gcgaacagtg gtatgagata gacgatatcc
     5701 aggatctgga catcgcagaa cttttattcc ttgaggatga tgtagagcgt tatcatacat
     5761 taacctcacg gtacggtgga ttctggcgtt tccctcatct gaaggactat tgttatctgg
     5821 taaacccgta ttttccgacc gagcgtatga tgaatgagat gaagtcaaat tttgatgtgc
     5881 tggtaagaca gtacccatcc ggtatgcggg tcaacagcct tctggctgca aagagttttt
     5941 ccgtatcgga agagcatatc gtgatcggaa atggggcggc agagctgatc aaggaacttt
     6001 tgactgagtt agagggaact gtgggtgtga tcagcccgac atttgaggaa tacccacatc
     6061 gctgcaatgg cagatatgtg gtatatgaca gcagagaaca tgatttttct tatgatgtag
     6121 acagcctgtg cagctatttt acagagcatc cggtcagttc aatggttttg atcaatccgg
     6181 ataatccgtc tggacattat ctggataaaa aagagatcag gaaactttta gactggtgta
     6241 agtcaaatgg aaccgcattg atcttagacg agagttttct tgattttgcg gacgatacca
     6301 gtgcatccat gctgtcagaa cgcatgatga aaaaatatcc gaagctgtat ctggtcaaga
     6361 gcatttccaa atcctatgga gtgcccggac tgcggttggg tatcctggca agttatgatg
     6421 aaaagatgat cgcggtacta aagaaaaaag tggcgatatg gaatattaat tcacttggag
     6481 aatttttcat gcagatactg gataaatata aagccgatta taaacagtca ctggtctggc
     6541 tgagagaaga gcgggctctc ttttatcagg aactttgcaa gataaaagga cttaaggtat
     6601 atccgtccgc agcaaattat tttatgtgtg agctgacaaa tggaaagcgt agtgaggcac
     6661 tggcagcaga actgttaaaa gataatatcc tgatcaaaga tctgagcgga aagattgaca
     6721 atggaaagca gtatatccgg atcgcgataa gagatcgcga ggacaatgag aagttacaaa
     6781 gggcacttgc aaaaagactg taaaagataa cgatgaaatg gagacaagag atgaatgtag
     6841 catttattcc agtgcgggga ggaagcaaat cgatcccgct taaaaacatc aaaccaatgt
     6901 gtggaaagcc actggtatat tggacggtag cggcagcctg cggctgtgca aaaatcgaca
     6961 aagtatatgt ggcaacggac agtgagaaga tccgggagac actgcttgag gtaaagcagc
     7021 aggagaaaaa cgaggcattt cagaaactgg aagtgattgg acgaagcgcg gagtctgctt
     7081 cggacacggc atcgacagaa tttgcaatgc tggagtttgc gaatgagcat gcgtttgacc
     7141 atattgtgct gatccaggca acatcgccgc ttctgaccgc agaggattta gacaggggat
     7201 ttgcgttata tgaagaagcg gatactgaca gtgtgctctc tgtggtacgg cagaagcggt
     7261 ttaactggaa ggtggcaaaa gatggaacgg cacaggcatt aaattatgat tatttccatc
     7321 gtccgaggcg acaggaattt gatggatact gcgttgaaaa tggggcgttt tatattacat
     7381 ccaaagagcg tctgtgtgag actggaaacc gtatttccgg caaggttaag gcagtggaga
     7441 tgagtgagga tacctttttt gagattgatg aaccatctga ctggcagatc attgaaaaaa
     7501 tgctggaacg acgtttgcac ggggcacagg aaaaaacaga tcaggatgag aaaaaagcaa
     7561 tcaagatgtt tctgacagac tgtgatggct gtctgacgga tggaggaatg tattattcgg
     7621 aaaacgggga cgagttaaag aaattttcaa cgctggatgg tcttgggatg cgcctgatgc
     7681 gagagaaagg catcctttgt gggatcgtaa ctggagaaaa tacgaagctg gtcgcaagac
     7741 gtgcggagaa actgcatctg gatatcctta aaatgggaat aaaggacaag ttatctgtag
     7801 taaaggaact gtgcggacag tatgggattt cattacagga agtggcatat gtgggcgatg
     7861 acatcaatga caaagagctt ttagcggcgg taggattttc tgccagtgtg ccgggagcga
     7921 tggacgaggt aaaagagatc gttgcttatg taacgaaacg tcagggagga agtggcgcag
     7981 tccgcgaagt gatcgaatgt attttgtctg gacgtaaata aagttgtatt aagatatttg
     8041 gagaaaaagc cgataaataa atatagattt ataaatactt tacgaaagga atgaccgcga
     8101 ggtcagggag caatcatgga agagagcaga acagaaaagc tggaggcgtt agagacactt
     8161 gtttcctata atgacaaagt tgttaaaaat gtaggaattt tgattaaaga attatccgga
     8221 cagagactgg atgatacgga taagttcctg gatagtattc tcaatgcgat aaactgggag
     8281 atccaagtat tgaacgcaac gatggatgtg atcaacaaag gaaaagagcg aatcatcaaa
     8341 gaagccttca atgagaaagt gatcgcattg ggtgaggcag taaaaggaaa agatgacgca
     8401 aaaatggcag atgcgttccg tgcgttagag ccggaactgg agaagcttgg agcagcagcc
     8461 agagaagtaa tcggttaaag ggaaagagtt catggtaaat gttaatactt ttcgtgaact
     8521 ctttttgtat tgtattggat aaaatatgag tagaatcttg atcatgtcag acattcatgg
     8581 aaatttgtct gcattaaata aaatctggaa aacagaagag atagaggaat ttgaaggcat
     8641 tgtattgttg ggcgatctga tcgactatgg accacactcc aatgaagtgg tggaaaagct
     8701 gaagtgcctg ccaaaacaca agatactggt aaatatctgg ggaaatcatg aaaaggcggt
     8761 cgtggatgga gacgattcga gattttccag cgaacgtggg aaaaagtgtg cagcacatac
     8821 cagaaaaacg ctgacaaaac agaccatgca gtatctggaa aatgagatgg atgagagcgg
     8881 tcacatggaa tttgaactgg cagggaaaaa atgtctggcg gttcatggtt cggctgatga
     8941 tttcttctgg aagagcattt ctcatggaga ggatcaggac gaatataaaa aatacgatta
     9001 tgtcttttct ggacattctc atatccctca ttattttgaa catttttatc cggcagaatg
     9061 taaggaatac cggaacaggg aaaaaaccgt gttccttaat ccgggttctg ttggacagcc
     9121 acgtaatcat aatgcaaatg cacagtatgc catattggaa ccggaaacga tgagcgttca
     9181 gatgaaagca gtttcctatg atatagagca agagatagca gcattttcgg atgaagtgga
     9241 ttctttttac aaagagagac taaggatagg tgtatagaaa tgaaaaaagt gtatttgtgt
     9301 atgtccactg atattattca gacaggacat atcaatgtaa tagaaaaagc agcggaactt
     9361 ggagaggtaa ccgtcggagt tttaagtgac aagtatgttg caatgtatga gaaatatccg
     9421 atacttccgt tggaagaacg tatgaggatc attcagaata tcaaaggtgt atcaaaggtc
     9481 gttgtccaga atgatatcta ttatgatgag accattcggg aattaaagcc ggatatcgta
     9541 atccacggag ataactggac cgatggatat cagaaagcgg tcagagatcg tgttattgag
     9601 gtgttagctg agtggggtgg cgaactgatt gaaatcccat attataaaag ctcaaatctg
     9661 catctgtttg aaaatgcgat gagtgagagc cgtggacttc cagaggtaag aagacaggta
     9721 ttgcgccgga agatctgctc aggagaggtg tttaaagtca tggtcgcata tgacggattg
     9781 agcgcgctgc tcgttgaaaa aacaagtatt gaaaaggatg gagaaagaag acagttcgac
     9841 ggcatctgga tttcaagcct ctgcgattct actgcaaagg gaaaacctga cattgaactg
     9901 gtcgatctga catccagact taattccgta aatgatatca tggaagtaac aacaaaaccg
     9961 atcattttcg atgcggatac gggcggactg gtagaacatt ttgtctacaa catcaagaca
    10021 ctggagcgta tgggtgtttc cgcagtaatt attgaggaca agatcggatt aaagagaaac
    10081 tccctgttgg gcaatgatgt ggaacagcat caggacagca tcgaacattt ctgtgagaag
    10141 atcagagaag gcaaaaaggc gatcggatca agtgcgttta tgctgatcgc cagaatcgaa
    10201 agcctgatac tggatcaggg agtagacgat gcgttagagc gtgcaaaagc atatgtggaa
    10261 gcaggcgcgg atggtattat gatccattcc cgtgcaaagt ctccggatga gatcttcgaa
    10321 tttgcagacc gcttcagaga aacggataaa gatacagcaa tcgttgtggt accgacgaca
    10381 tacaatcagg taagagagag cgaatttaag gagcacaaga taaatgtggt tatttatgca
    10441 aaccatatgt tacgggcagc atttccggca atgcaaaaag tagtcacctc tgttctggaa
    10501 aatgagagat gctatgaggc aagtcaggac tgcatgtcga tcaaagacat tttatctttg
    10561 gttccggtag aataaagtta cagtaatgag agaaggcagc gtatgaagaa attatatgta
    10621 ataagtggaa tgacaggaat gacaggcaac gagcttgcac gccagatcgt aaaacggggc
    10681 gatgatgtga tcggttttga taattttttt gcatcatcca cagaaacgat caaggatgtg
    10741 atcgattcgg aacacctgga attttttgaa ggcgatatta ataacgatgc acagatgaaa
    10801 gaactggaag agaaggtaac cgcaagaaaa gcagagtatg aaaaggtgac ctatatcaac
    10861 tgtgcagcag ttgtacatac cgaacatttt tatcatgttg accggacatt tgagacgaac
    10921 gtgatcggaa tgaaaaagtt tttggagcag gcgatccgtg tcggggcaga cagttatatc
    10981 aactgttcca catcagaggt ttattcgatg gcatcctgga aagagggcgg cgtaaaagag
    11041 gatgatttcc tgcttctggc aacagcagaa cacagccaga ggaccagtta tgcaaccgga
    11101 aagcttctga cagaattttt tatgaaagat gcggtagagc gtggaatgat aaagggatgt
    11161 tcccttcgtt ttgccaatgt ttacagtaaa aatgagctgc tggcaaaaca tgtgatcccg
    11221 catgtcatta ccagtttgat gaaagatgga aaagtaactc tgttagaaaa ttccaaagta
    11281 aataaaagaa ctttccttca taatattgac agctgtgcag cagtgcttgc cgttgcagac
    11341 acagatgcgg ctctggacgg aactgtttat aatgtggcaa cggagcagga agtttccatg
    11401 atcgaactgg tagatgtatg tgcgaaagcg atcgggattg aaaaaccgga aattattttt
    11461 gaaggatatc gcgaatccga tccgcagaga cgtgtattat ctgccgcaaa gataaaggcg
    11521 cgtacgagat gggagccgac gatcacgttg gaacagggta tcaaaatgtg tgtagattac
    11581 agaagacagg tggaaggaaa gtaaatgaaa acggttatag ttgcagttgc gggcatgtcg
    11641 atccgattta atcaggatat ggcagaaccg gtgttgaaag ggatttacac agagggtgat
    11701 gtccgtaaga cactgttata ttccatctta agaaaatgca aagggtttga ccgggtagta
    11761 ttggtaggag gataccagta cgagaaactg gttgaatatg tatctgcctg taaggaggat
    11821 tttccatttc agatccagat ggtatacaat tcaaactatc aggaatttgg aaccggttat
    11881 acattaaagc tggggctgga acaatgtctg caggataaca gttcggaaat taccctgatc
    11941 gagggcgatc tgtttttcga tgaggcatct ctggatgatg taaaaagatc aacgcggagt
    12001 gttgctacct ataacaataa aacgatctac agcaacaaag cagtgatcgc atatataaat
    12061 gaggcgcatg aactgaaata caaatttagt accaatcatg gatcggtgga gatcgcagag
    12121 ccatttctgg caatttataa ttcgggacag atctggaaat ttgctgatac agacgttgtg
    12181 aagcagctgg tatcagacag cccggagacg atgtggcagg gaacaaatct taagtttatt
    12241 gaggaatatt tccatcagat cagtgaggag gaaagagagc tgcttcctct taaaacatgg
    12301 gaaaactgca atacgaaagc agattattta aaatacgaag aacagttgta agggtaagac
    12361 agatgaacaa agaggaaagt tcgaagaaga taaaagttgc ctttttcccg tataaaattt
    12421 cgatgtggga ttctctggag agcatatggg aagctacaga ccgggatgaa agctgtgaat
    12481 gtcaggtcat accgatacca tactattcca aaaacgcaga tggggagatt gaaaaagaac
    12541 attatgaggg agcggcgttt gctaaaaaag ttccgatcat agattatcag acctattttt
    12601 tggaacagga aatgccggat gttatgtata tccacaatcc ctatgaccag tacaataaag
    12661 taacgatggt gcatccgcgt ttcttttcca cagaactgaa aaaaggcgga ggcattctgg
    12721 tatatgtgcc atattatatt tcgggatttt gtgaaaaata cgaaaatatg ttaccggtct
    12781 gtgccaatat gggagcagta tacagcgatt accttatcct gcagaatgaa aatctgaaaa
    12841 atgcgtacgc attttgcggt tacccggaaa gaaggctgct ggtattagga agccctaagg
    12901 tagatgctgt ttataagatc ggcgaaaagc agttctccaa aatagatgag tggaaaccgg
    12961 tcatagaaaa tcgtaaagtg atcctgttaa atacgagtat taccacctgc ctgacaaatg
    13021 ccagctggct ggaacagatc cagaaactga tcgaaccgat cttgcaggat aacaggctgg
    13081 cattgatctg gcgtccgcac ccactgttgc ttgatacgat gagatcaatg ttacaaaagc
    13141 aggcggaata tgacacgctg ttggaacgca tccggaaagc gccaaatgcc atgattgatg
    13201 acagtgatac ggcagaagct gcgatgaaag catcggatgc catgatcagc gattacagct
    13261 cactggtaat gcagtataat ttcaccggca aaccgtccta tatactgacc gggaaaagcg
    13321 aaaatcgaaa ggattgtgtt ttttgtgatt atttttcaaa ctatttcaga gaagatggag
    13381 aggatctttc tgatttttta aatatggtat tggctggcat tgatccaaag cagcaggaac
    13441 gaatggaata cgcaagaagt tcaatggcaa ataccgatgg aacctgtggt gaaaaagttc
    13501 atcgcgagat atgcaaaaaa gtaatgacag gagcgaacag ataatatgga agaaatcaag
    13561 attacagaag aacagcggga gcggatcaga aaaatccagt tggagatgat aagggaagta
    13621 catcggattt gcgaaaaaaa ccatatcaaa tatgtactgg gatatggaac catgcttggt
    13681 gcagtaagac ataagggatt tatcccatgg gatgatgatg cggatatttt aatgctgcgt
    13741 aaagattaca gaagattttg cgaggcatgc aaaaaagaac tgccggaaaa atatttcctt
    13801 caggatgaat gttccgatga gtattatctc tggggatatt ccaagctgcg caatatgaat
    13861 acaacttatg tccgttgcgg acaggagcat attccatata aaaatggcgt atttatcgat
    13921 atctttccac tggataatgt gccgtggttt ttaccattcc gtattttgca ggatgcgtat
    13981 ggttttgtac tgagaaaaat gttgtgggca aaagtcggaa aaaatacgga gaaaaatcca
    14041 ctggtacgtc tggtatacaa aatactggca ccgatcccaa agagtacgat atatgcaatg
    14101 cgtaatgtga tggtacataa gggaaacaag gtttcagaca gagtccgctg tctgttgttc
    14161 acggcaccgg gaaaacattg gaataaaaag gcaaacagtc tgtattccag atatggattt
    14221 aaaagggact ggctgttaga tcgtgaaaaa tatgtctttg agggagaaga attctgggga
    14281 accagagaat atgacgattg tttgtcatac ttatatggcg attatatgaa acttccaccg
    14341 gaagaaaaga gagtgggaca tgcgccggta tctaaattag aattaaatca ggagggactg
    14401 tgatcaatgg ataaatcata ctgggataca ttttatgcag caaataaagg agtgaatgag
    14461 ccgtcattat ttgcaagatg ggtacttgag caggtagaaa cagacaaaaa aattgtagat
    14521 atgggttgtg gaaacggacg ggacagtatc tatttcatgg aaaacgggat gcaggtctat
    14581 gcagtagatg cttccgatgt tgcaaccgag catattgcgc aggtttatgc cggaaaaata
    14641 aatgtggaaa acaaagacta tgtcagctat ctgggagaga gaagcgaaga gtttgattat
    14701 ctctacagca gatttaccat ccatgctatt ttagaggaag agcaggaatg ttgtataaaa
    14761 aatgcttata aagcattaaa accaggcgga aaatttttca tagaagtaag atgcgtaaag
    14821 gatgagttgt ttggaaaagg aactctggtg gcaaaaaata catacttcta taatggacac
    14881 aacagaagat tcatcgaaaa ggaagaatta gcacagcagt tgaccgaaac cggctttcag
    14941 gttatctatg cagaagaaaa aaccggattt gcaccatttg gggattcgga cccggttgta
    15001 ctccgtatgg ttgcggtaaa ataataaaaa gcctaaggaa cggagcataa caaggcggct
    15061 taggatagat tcaaggatga ggtgaaagaa aatgaaggat ctggaaacca gattacagct
    15121 tgtaaaaaaa catattgaag acaataacat taccgtgatg atcttaggac tgggaagcgt
    15181 gggaacctat cttttggatt ttctgaccag tagaaacgac gcatcaatga aacttgtcgt
    15241 ggtcggaaga aatgcagaga agctggaaaa caatgcgaat attgtccgca tcagtgcatt
    15301 gatccgtcat gtgaatcgct cgcagatcat cattgagagc ggagtggatt ttgatgaagt
    15361 cggacaggtg gcagaatgta tcaaaaagta tcaacctgat tttattgtca attcaagccg
    15421 tgtgtattca ggattgaagt atggcagtat ttcatggaaa aatttacgtg cgtatggtat
    15481 ctggtctccg ttagcgatca agtatatcaa aaatatcatg aaagcatgtg aaatcgctga
    15541 tctgaacgga attgtaatta atacatctta ttctgatgcc gtaattccat ggttaaaaac
    15601 ggcaggacag ccatatcctg atttcggaag cggcaatatg aaccatctgg taccgcggat
    15661 caaatatgca gttgccgaga tcaaagagat cccggacttc tggaatgtgg atgtgatgtt
    15721 tgcaacagca catttccatg atgtcgtgat cagtaaagag ggacagacag aggaagttcc
    15781 acagctgtta aaggtatttt atcaggggaa agaactggat atcgatcaga atgatatttt
    15841 tgcacggtgt aaaataacaa tgccgactga cgaaaaacga aatatgatga acgcatccag
    15901 caattacgat attatctgtt ccattatcga tgctgtaaga gagagcgaca gcagaaaaat
    15961 attctctccg ggtgtatttg gagaaatcgg tggttatccg gtcagaatcg atgcaacggg
    16021 agataagtta caggcataca ttgatgaatc ggtatttacc ttagagcaga tgagggaagc
    16081 aaaccgcaag tcgatcgctc tggacggtgt tgaaaatgta gaagatggca gcctgaccta
    16141 cacagatgat ctggtacgga aagtagcaga tgtgtttgac gttcgtctgc ctaagacagt
    16201 agcatttgaa gaaatcgatc agaccgcagc ctatattatc gataatatca ttgttccgca
    16261 gctgaataaa aagtaaagga ccataaaaat atgaaagtag aatcatttgt agaggaaata
    16321 agatctctgg gaatagaaac gatagcagga gtaccggatt cggcattaca accactttgc
    16381 tactatctga atgcaggaga atgtggattt caccattttg ttccggcaaa tgagggagct
    16441 gcggttggta ttgcgatcgg aaattatctg tccaccggaa aaccggcatg cgtatatatg
    16501 cagaacagcg gaattggaaa tattgtaaat ccggtaacct cacttgcaaa taaagcggtg
    16561 tacgatattc cgattttatt tgttgttgga tggcgtggag aaccgggaaa gaaagatgaa
    16621 ccgcagcatc ggtttatggg agagatcaca acaggtattt tagatgtgtt agacatacca
    16681 aatgcgatac tttcggctga aatgactgag caggaaataa aaaatatttt taaaaatgcc
    16741 aaggaagcac tttccgaaaa taagcagttt gcaattattg taaagcggga tgcactggaa
    16801 gcaggggtaa agaacgcata ccagaatgat tatacccttt gcagggaaga tgcgatttcc
    16861 gagatcataa aagaggttga tgcaaatgat gtcattgtat cgacgacagg taaaatttcc
    16921 agagaagtgt atgaacagtg cgacaagcag ctgggacatc acaagcaggc atttctgacc
    16981 gttggtggaa tgggacatgc cggtatgatc gcatatggga ttgcacagaa caggacagat
    17041 aaaaaggtat actgtatcga gggagatgga gcagtgctga tgcacatggg ggaactcgca
    17101 tttctggcaa aacagcagcc gaaaaacttt atccatatct gtctgaacaa cgaggcgcat
    17161 gagtctgttg gaggaatgcc aaccggagca gttgggatcg acttttacaa gacagcacgg
    17221 gaatgtgggt attcctatgt ggcaagtgta gacaatttag aggatctgca aaagcaactg
    17281 caatacattg cgggcataga gggacctgtc ttccttgagg taaaggtaaa aataggagcc
    17341 agagcagatc tgggcagacc gaaagagagc gcggtcgaaa ataaagagaa ttttatgaag
    17401 tatcattttc ctgaggtagt ggactagtat agctgtcagt aattaactcg actttttgac
    17461 tggcaacgta tcaaccacca cttcttcatt tggatcaatt tcttcaagtt tgtacttcca
    17521 atgatatata acaggttctt catttacttc atcaaagtat ttatatatac gctgcacaag
    17581 ttcatcctta gtttttacac gaatgccctt gagcatctgg cgagtaagtt tactgaagaa
    17641 gccctcaaca agattcaacc atgaaccgtg ctttggagta aatacaaatt caaatcttcc
    17701 tggtacggtt gcgaggtatt ttctggtttc ctcagaagaa tgaactttaa ggttatccaa
    17761 caccagacga atcttatctg attttggata cttgttatca agttttttaa gaaattcgat
    17821 atagtcctta ctgttatggg actctttaac gagtggaatc gcctcacctg tttgcaaatc
    17881 tattccggca agcagtgaaa tggttccaag acgcctgtac tcataatctc ggcttatggt
    17941 cttatgatta ttatccggct ggatatcttc tgatgtggtg gcaattgcct ggattccagg
    18001 tttctcatca taagagagta catgcaccac ctgatcatct tcacaaaatg gaagaagttg
    18061 tcctttttta tcgaactgta atgatagctg tttatatacc agaaggacat tgtgcatctt
    18121 ttggtcaaaa tccggatcac gattttcaca gtaataagtt attttgtcag gcttaatatc
    18181 tgcctcttca agtattgtgc gaacctttga ctgacttata gttgataacc ttgtataacc
    18241 tgcattttct gcaaacttat tgatatgttt tgtgagaagc gcacgtgtcc atacttctgc
    18301 tgaatagcca agattaaccg gcttctgaca tgcgatattt ataatccacg tcttttcgtc
    18361 atcggttatt tcagcattac gaccacgacc gggagcatca aacaaggcgt tttcgacacc
    18421 gccctctttg aatttattca agcacaacat tacactgcat ctattgatgc ctactttatc
    18481 agcaatatca ttaatagaaa caccatcagc acgtaacaac agtattcttg ctctacacac
    18541 ggtttgtgcc tgtattgttc tagcacgagt ttgtaattca agatacgaac gctgctcctc
    18601 tgttagtgtt attgtgttta cttttctgcc catgaatatg acctccctat acaattatat
    18661 gaagattata tcatggaata cttattgagt cgagttaatt aaaaacattt atactagaaa
    18721 gaggaaaagc atggaatttc cagaggattt tttcaaaaaa gaatgcagat gcggctttga
    18781 agtgccggag atgatgaaac gtgcatgggc agcgcagatg gaagtacttg aagttgtggg
    18841 taaggtttgt gaaaagcatc atttacagta ttatgcggac tggggaactt tacttggagc
    18901 gatccgtcat aagggattta ttccatggga tgacgatatt gatatctgtc tgagacgaaa
    18961 agattataat gaactgatcc gcgttctgcc aaaggggctt ccacatggat ttgttgtggc
    19021 gggaatgtac gcagcttctg aaagacttca aaatgcagcg tatgtaccgc agctgcgtgt
    19081 gatcgcggat gaaacgctgt gggattttaa ttcctatatg cgcagatttc atggcttccc
    19141 ataccagaga gtcgggattg acatttttcc gatggatcgc atgccggaag atctggaaac
    19201 ggcaaagctg cagaaggagg tcatccgtca gggaattgca atattaagag aatgggatcg
    19261 tctgcaggaa agcgggcaat tacagggata tttaaaagga tatggcgaac tttgtaatgt
    19321 ggagatccct cagagagatg atcttaaaaa ctggatgtgg cgattgatcg atgcactgtg
    19381 cagcctgtat caggatgatg acacagagtt tattacgaat tggaatgtgt ggatggcaaa
    19441 gccacgttta taccgtgtaa aaaatgaatg gtttgacgag atgcgttatg tgccatttga
    19501 gcatgtgcgc atcccggtac cggggaatta tgatgaggtg ttaaaggctc agtttggcga
    19561 ttatatgaca ccaagtcagg taaaaggcgg tcatgattat ccgttttatg ctgaaatgga
    19621 gaaagagctt gtaaaacaga taagagcggt gggcttcatg ggaagcgtag aagaattttg
    19681 tgagaaagtt tcgacaggcg aactccaggt ataatggagt tactctgaat aatgttttct
    19741 cacaaaatca tcaatacttc cggtatatcc atgagcatcc agatagtttc ttaatgcatg
    19801 ttcttcggtt ttgtaaaaag gataggtgtg cgtttgaaca gttatgaccg ggtttctgta
    19861 atcaccgtag cggttggtaa ggatctcgtc atactgtttt ggcacagtaa ccataatatt
    19921 ttcgaatggg acggtaatcg cctcagcaaa ccattctttt ggggtggcga tctggcggtc
    19981 atttgtaaac cagaaaccgt ctttggcaat gtcattgccg tcgttttcct gatataacgc
    20041 gcggatggaa tccgagagct gtatcagagt gcgaagaata tttgcatcac gtgcaatgtg
    20101 ggtactgcat agcgattcga tctcttttac attttcttcc cttgtgatct cgttggtttt
    20161 ctcccagttg cggacacaga acacgatttt ctgaaccagg tactgttgaa gggaactcag
    20221 ttcgggatca tccgggagat aatcaagcgg gaagatatcg atccccatat tacgatacgg
    20281 aaagccgtga aaacgctgca tataatctga aagcttccag tcggacgaaa ccgttgcaac
    20341 gacagactgg caggttggca aaaacaattt atctgtttgg gcataaggtc cggcgagtgc
    20401 gatcccattt ggaagttcag aaggaaggac gcggatcagc ttgttgtaat caggccgttt
    20461 gagagcaata tccacatcat catcccatgg aatgaagccc ttgtggcgta ttgcgccaag
    20521 cagtgtgcca tattcagcaa aataggtaat atcatattta ttgcagatat cgatgatgat
    20581 ctgcagtaat tcaagctttg ccgcccaggc gcgcttcatc atctgcggaa ctaaaaaacc
    20641 attgcgatat tcgtcttgga aaaagttttc agggaaaatc ataatagggg actcctttaa
    20701 ggaataaaaa atactattaa atatatcggc tgaaataaat gaaaaatgat acatattatg
    20761 aatagaaaat ttgcggggaa gattaagaaa aagagggcaa atgccgatac actatatagc
    20821 taattatcaa ggaagatgat tacagagata caagcggtag cgtatctttg gaaaaaaagg
    20881 acacggaggg aaatatgggc agaatagttg taaaccataa catgcagtcg atgtatcaac
    20941 atcggcagtt gaagattaat acagaaaatg tagacaaatc ttcagaaaaa cttgcatctg
    21001 gttacaagat caatcatgca aatgatgagg cggcagagct tacagtatct gaagcgatga
    21061 gaaaccagat cagaggtttg aacaaggcat ccaataatat tcaggatgga attggtttgg
    21121 ttcagacagc agatgcggca ttggaagaga cccagacgat attggatcgt atggtagaac
    21181 tgacaacaca ggctgcaaat gatgtgaaca ccgaggaaga tcgtaaggca atccaggacg
    21241 agatcgatca gttgaacaaa gagatcgacc atattgctta tgacaccaat tttaaccaga
    21301 attacatgct tgcagaggga acgccaaaag cgaaaccagg atttttttat gttcagacag
    21361 gttctctggc agaacagagt attatcatca attttgtaaa tgcgagcaag gaaagtcttg
    21421 gtgtagataa ggttgatgta tcgaatcatg aaaaggcatc agaatcgatc accatggtgc
    21481 aggatgcgat tgagaaagca gcaggatgga gagacgattt tggagcagtc tgggagcagt
    21541 tagcgcgtgc ggtaaaaaat gcagattaca catcccagaa tacacagcag tccgagagca
    21601 atattcgtga tactgacatt ggtgatgaaa ttctgggata taccacaaac cagatcctgg
    21661 taaatgcgtc acagagtctg ttggcacagt ataatagcag taaggatgcg gttctggtat
    21721 tattaaggta atatagttag agatgggata acagcggttg attaatatat gtcatgttga
    21781 tcaactgcta ttatttttta ggggtaaagt gtgagcttgt gaaaccgcag aatgatctgt
    21841 actggaacaa taaacctgaa ttattcacag caaagccgtg aacgtggctg aaagccacat
    21901 agctgctgta ttttaattgc acattgtttt ctgacgaatt gagagacgtt atggctacat
    21961 ggatcatttt ttgattcatg gtgcaatttt cagattagag attgctccgt gaataattca
    22021 ggataaatat gtttttgact gttatctgac aaaataaagg agatatggca tgcaggcgat
    22081 tatcttggca gcaggaatgg gaaaacgttt gggagagttg acgaaaaata atacgaaatg
    22141 tatggtggaa gtcggtggtg tgcggctgat tgaacgtgcg cttcgcatac ttgacagaaa
    22201 aaaattaagc cggatcattc tggttgtcgg ataccagcat aaaaatctgg tttcttttgt
    22261 tgattctttg tgtcttaaaa caccggttga gtatattgta aatgatgtat accataagac
    22321 gaacaatatt ttttcgctgt ctctggcaaa agatcagatg atgcaggaag atacgttgtt
    22381 attggaatca gatctgattt ttgaagagaa cctgatcgat atgctgttag aagatgaccg
    22441 ggatacgctt gcattggtag acaaattcga aaactggatg gatggaacct gcatcgtggt
    22501 cgatcaggac gataatatta ctgatttcat tccgggaaaa ttattaaaat accatgagaa
    22561 agaacattat tataaaacag taaatatcta taagttcgga gcacagtttt caagagatgt
    22621 atatgttcca tttttggaag catatgcaaa ggttatggga aataatgaat actatgagac
    22681 tgtgatcaaa ctcatactga tgcttgataa aaatacgatg aaggcaaaaa ggctaaatgg
    22741 cgaattgtgg tatgagattg atgacataca ggatcttgat attgctcaga cgttatttat
    22801 cgaggatgat gtagaacgat atcatcatct gatgcaacgg tacggaggat actggcgttt
    22861 ccctcattta caggattatt gttatctggt aaatccatat tttccgacaa agcgtatgca
    22921 ggaggagatg gaatctaatt ttgatgtgct ggttcgtcag tacccgtctg gtatgacagt
    22981 caatacgctt ctggcggcaa agagttttga tgtgcatgaa gaacacattg tgatcggaaa
    23041 tggtgcagca gagctgatca aaggattact ggaagaactg aacggaaaac tgggtgtgat
    23101 ccgtccgact tttgaagagt atccaaaccg ctgggagaaa gatgttattg catacgactg
    23161 tacggaaaac gatttttcgt acacggacag ccagttaatc caatacttca cagaaaatcc
    23221 agttgatacg ctcgtattca tcaatcccga taatccaacc ggtcattgca tggatgcaga
    23281 cgggataaag agcctcctgc agtggagtaa ggaatgtggc ataaatctga tcgtggatga
    23341 gagttttctt gatttcgcgg atacagaaga tttatcatta ttatcggaac aggtgctaaa
    23401 agaaaatcgg aatctctatg tggtaaaaag tatttcaaaa tcatacggtg ttccgggact
    23461 cagacttgga atcttggcga gtggaaatac ggatatgatt gaacacttaa agaaagacgt
    23521 atcgatatgg aatatcaatt ctatggcgga atttttcatg cagatcctgg acaagtataa
    23581 aagcgattat acagattccc tgcgaaaaat aaaagaagaa aggtcccgct tttttgatga
    23641 actgtgtatg atagaaaatt taaaagtcta tccgtcccag gcaaattatt ttatgtgcga
    23701 aattttagat ggaatgagca gtgaggcact ggctggcaga cttttaaaga aaaatatcct
    23761 gatcaaggac ctgacaggga agatacataa cggaaagcat tatatcaggc ttgcggtccg
    23821 gggggaagag gagaaccgga gactggtgga gaaattgaag gtatgtatga agcagtagaa
    23881 gagagctggg gcctgaaata tggttattac aaaacaactg caaagatagt agaaaatgct
    23941 tgcatagaat gcacaataat gtcacaattg taaatgctat tgaagttcaa gaatgtatcg
    24001 tggtgataca tggtaaaata cgtaacaaga ggagaaatat ggaagagaaa agagatgtga
    24061 tatatctttc ttccagagag gcttttttaa aagttttgtg aatagagcgg aggcttgaaa
    24121 atatggcaaa tgaaattgtt attgttatta gtttcatttt tactatagct gcaatgtgta
    24181 aagtatggaa tttatatgca atgaaaaaat atagtgaatc caaagaagag aggttaggat
    24241 tgacatacgg attttatgta gacaatatgc aatttgttga aattgaagga ataggaaatg
    24301 atgaaaatgg agattttgat attgcaaagg ccattaagaa aatagaaatg ccggatgatg
    24361 taaggatcaa agcataatga ataaaataga ttttttagaa ttttataatg gtgtagttaa
    24421 aaaactaggg gtgcatttgg aaaatgagta caggcaattt cgtttttgcg ataatccgga
    24481 ttcattgtat gaagaatatc tcaatcaaaa gaccatatta agagttttat accaaaagaa
    24541 aaatggtgaa agtaaaactt tattagaccg gcataaagta tgtgcctgta tgacagctgc
    24601 aatcattaag gtcaggctgg taagcggaaa tatccaaacg gatgatagtt tttctttatc
    24661 cgttgcatcc aggattaacg aacaactggc ttttatgagt acgtgggagt tatttttggg
    24721 tttcataagg cttcacaaag aagagacaga caaaaaaaga tgggcatatc agatgttaga
    24781 tgatctggta tgcttttttt ataataggga gtgcctcaca gctgctccca atactcctta
    24841 aacttcacct ccgtcatccc ttccccgatc atccgataca gctccatctg ctttggaatc
    24901 agagcgctgt aaatggactg cgcataatcc ggcacctccg caagaacggt tttttctaat
    24961 tctttgtaga aagcatagga gggtttaaaa tcccggagtt ttgcaaaata cagtgtctca
    25021 tacagatagg tatggagaaa atatagtttg atttcatcat agtattcttt gaaaaatgga
    25081 gtttttttca tgaaattcca gacagcaagc tggacgtcgg catgcatttt tagggtttct
    25141 tcctgtctca tatcatttcg catggttcca gaatcatttt gtctgtaata atagtaggca
    25201 tcgtttaaga ttacgatttt atttgcaaaa tataaaagcg ggtatacaaa aagtggctcc
    25261 tcataaatga catgttctgc gtaggctgta tgagcctcat tcagcagagt gtggcggtaa
    25321 agtttattcc agcagccata ggtaactttt tctgagatta gaaatctttt tcggtcactg
    25381 acagaagaaa tttcaatcac ttccggcgta atgttccgac cggagtccac ggcacccaga
    25441 cggtctgtat aataaaaata ttcaaactgg atgatatcag catccgattc tttggctttt
    25501 tcataagttt ccaacagaaa attttcagag acaaagtcat cagcgtcaac aaatgcaata
    25561 tattcgcctg ttgcatactg cagggcaaca tttcttgcac cgccctggcg catattttcc
    25621 tcaagtttta agatcataat gctttccgga taggcgcgtt caaattcctg cagcatgttc
    25681 caggtagcat cctcatctgt ggatgcatcg tctacaaaga tcagttcgat ctggtcaatt
    25741 ccgattgtct gctgtacaag tgacataaag catttcggaa gatattttgt tgcattaaaa
    25801 catgggatga tgacacttac ttttttcata gatcgaaatt ctcctggtaa aaaggttacg
    25861 tatggtataa taaacaaaaa tggtatatta ttaatttatc acaacaaaaa ggaatgcaca
    25921 atatcagtct gaaaagcagg gaggttacaa tgtctggaaa tatagcgatc ggtatacagg
    25981 atttttccac aatcatccag ggaaactatt tttatataga taaaacgcct tttattaaag
    26041 aatggtggga ttgcggggac agtgcgactt tgatcacccg tccgcatcgt tttggaaaga
    26101 cacttacaat gagtatggtg gagcagttct tttccataga ctatgccggc aggtcagatt
    26161 tgtttgaaca tctggcgatc tggaaagaag aaaaataccg tgagctgcag ggaacttatc
    26221 ctgtcatcag tctgtcattt gcgcggatta aagagagaga ttatgagaaa acaaaacaaa
    26281 agatgtgtga ggtgttaaga aacatatata taaagttttg ttatattaaa gacagtgaaa
    26341 agcttacaga tgccgacaga gcatattatg agcgtatgtt ggaggaaaat ataaaagaga
    26401 cggatgcgac atcttcttta tatcagttat cagatttcct gtatagatat tatggaaaaa
    26461 aagttatcat tttgttagac gaatatgata cacccatgca ggaagcattt gtggatggtt
    26521 actgggatga acttgtcgca ttcacccgaa gcctgtttaa ttcgacattt aagacaaatc
    26581 cggcactgga acgtggaatt atgacgggaa tcacaagagt aagtaaggaa tccgtttttt
    26641 cagatttgaa taacttaaag atagttacga ctacatcaaa tgaatatgct tctgtatttg
    26701 gttttacaga gaaggaagtc tttgatgcat tggaacagta tggtcttgag aaagaaaaaa
    26761 aagaggtaaa aagatggtac gatggtttca tttttgggga acacaaagat atttataatc
    26821 catggtcaat tttaaattat ctcgatacac agttatacaa aacattttgg gcaaatacaa
    26881 gtgcaaatag tctggtagga aaattgattc aggaaggaaa ccgtacaatt aaggaaaaat
    26941 ttgaaaaatt attgtgcgga gaatacatct ggtcagaaat tgaagagcag attgtataca
    27001 atcaattaaa tggaaatgaa aaagcagttt ggagtctttt gctggcgagt ggatatttga
    27061 aagtattatc ttatgaaacg tatcaggata ttgaggaggg gaagatgccg aaataccagc
    27121 ttgcgttgac gaatctggaa gtaaagttaa tgtttcaggg tatggtacat gactggtttg
    27181 ctcctgtaca gccagattac aatgattttg taagggcaat gttacttggt gatgtggatg
    27241 cgatgaatga atacatgaat cgaattgcta tacagacatt tagttatttc gacaccggag
    27301 agagggcatc tggggcagag cctgagcgtt tttaccatgg ttttgtatta ggtctgcttg
    27361 ttgatctgcg ggatagatat taccttaaat ccaaccgtga aagtgggttt ggcagatatg
    27421 atgtaatgtt agaaccgaaa aattcaaagg aatgcaaagc agttatttta gaattcaaag
    27481 ttcgaaatcc acgaaaggaa aaaagtattc aagagacagt tctgtctgcc ttaaagcaga
    27541 tctgtgagaa aaaatacgat gcagacctgc ttgataaagg aatcagaaag gaacagatat
    27601 atcattatgg atttgcattt gaaggcaaaa aagttttgat tgggacagac agggaggagt
    27661 gaatatgccc accaatatag cgatcggcac acaggagaac aaccacatgt tatcagtctg
    27721 catcatcacc aaaaatgaag aacacaatct ggcacgctgc ctgaaatcat tccagaacac
    27781 cggatttgaa ctggtcgtag tagataccgg atcgacagat cagacaaaaa aaatcgccgc
    27841 agaatatacg gaaaatatct atgatttccc atggtgcgat gatttttcgg cagcaaagaa
    27901 ttttgcggtt tcaaaagcag cacatccgta tgtgatggtc attgacagcg atgaatattt
    27961 acagcagatt gatcgggtac agttagagaa aatgattgcc gaacatccag gtgaggttgg
    28021 caggatccgg agaatcaata ttatttccgg aaaagatgga aagcaggaaa ataaagagtg
    28081 gatcaaccgc atttttgcaa aagaaagttt tcattacacg ggaagaatcc atgagcaggt
    28141 aactgcctgt gacgaaaagg aatatcgtac atacgaagca ccggtcgtca tcggccatac
    28201 gggttatgat cttccgaaga aagaaaaaaa ggcaaaagcg ctgcgcaaca taagactgtt
    28261 agagcaggaa ttaaagaatt caggatggga tgaaaaagtg catgccacgc agttagatca
    28321 gaatatcgca aagcaggata cggatgcaga gcagaaatct aaaattacgg atgcaaaaaa
    28381 agagcagcag atcccgtatc tattgtatca gcttggaaaa agctattaca tggcagaaga
    28441 ttataacgag gcatgcttct ggttcgccca tgggctcagt tatgaccttg aaccaaagtt
    28501 agaatatgtc atcgatatgg tggaaaccta cggctatgcc ttgatcaaca gcggacgcgc
    28561 cggggaagca cttttctttg aaaatattta tgaagaattt ggaaatagtg cggactttca
    28621 gttcctgatg ggactcattt atatgaataa cgctatgttt gatgcagcag ttggagaatt
    28681 tttgaaagcg gtcaaacacc gggactgcag gatggcggga gtaaattcct atgcagctta
    28741 ttataatgtt ggagttattt atgaatgcct ggagaaaatc agtgaggcaa agtattatta
    28801 tcagaagtgc ggtaattatg agccggcaaa aaaacgttta aaattgataa acagttaaat
    28861 ttgttatagt cagcttat
//
