LOCUS       c00024_gnlPro..        13325 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NAMAOLGB_24.
ACCESSION   c00024_gnlPro..
VERSION     c00024_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-08 00:01:11
            Original ID  :: gnl|Prokka|NAMAOLGB_24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13325
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13325
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[366:3325]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      367..3325
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13325
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13325
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             367..2595
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_1"
                     /sec_met_domain="Gly_radical (E-value: 1.9e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2600..3325
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_2"
                     /sec_met_domain="Radical_SAM (E-value: 2.6e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFQTVQVN"
     CDS             complement(3558..4820)
                     /locus_tag="ctg24_3"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVLTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRSEPQQEAIAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(4872..5420)
                     /locus_tag="ctg24_4"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5608..6360
                     /locus_tag="ctg24_5"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6465..7463)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg24_6"
                     /sec_met_domain="LysR_substrate (E-value: 2.8e-46,
                     bitscore: 149.3, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 4e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMELKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7533..8006
                     /locus_tag="ctg24_7"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(8110..9108)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_8"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 2.3e-69,
                     bitscore: 225.5, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDINQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9163..10431)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_9"
                     /sec_met_domain="MFS_1 (E-value: 1.5e-11, bitscore: 35.6,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRCAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(10681..11694)
                     /locus_tag="ctg24_10"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDATAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPGGYVLPVTLKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11717..12826)
                     /locus_tag="ctg24_11"
                     /transl_table=11
                     /translation="LLACFVLPMILAGCNDADYQVIDNAIYLNEASENGSAKVTVDPEN
                     VTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTYDKEIKIAAG
                     DVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDKPLIQSVPFM
                     NTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVYIRFGDAMIP
                     YNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQTKGGPVRFD
                     KMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGYWKMDEGKGN
                     AFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 caatttactg attttcagcg tttattgcgg agagacaggg attcgaaccc cgggtacctc
       61 gcagtacaac ggttttcaag accgccgcaa tcgaccactc tgccacctct ccagaactac
      121 ggttaagtag tgcttttctc ttaaagcgct gcaaaggtac gaatcatttt ttaacttgca
      181 aattattccg caaaaaaata ttagaaaagt atatttggaa gtaataaccg ccctctggct
      241 tctccccata aataggtatt tttatgctat tcaacataaa ataggaccct tttatatacc
      301 taaaccgaaa aaaggttgta aatttgcgcg ctctaaagga taactaacca ctaactgatt
      361 aattttatgg aactgaataa gacctttaaa gatggacttt ggagcaaaga aatcaatgta
      421 agggatttcg ttagtaacaa catcactcct tatgaagggg atgcttcttt cctgcaagga
      481 cctaccgaac gcaccaaagc tgtctggaat cactgtctca aagctctcga agaagagaga
      541 aacaataatg gtattcgtgc actcgactac acaactgtat ctactataac ctctcaccct
      601 gccggctaca tcgataaaga aaacgaactg atcgtcggac tacagaccga tcaggtgtta
      661 aaacgtgcca tcaaaccgtt tggcggaatc aatgtggtta tgaaagcttg ccgtgaaaac
      721 ggagtggaag tagatgacag agttaaggat atcttcactc actatcgcaa gactcataat
      781 gatggggtat tcgatgtgta taccgaagaa attcgttcgt tccgttcatt gggattcctt
      841 accggacttc ccgacaacta tgcacgcgga cgtatcatcg gtgattatcg ccgcctggct
      901 ctctatggtc ttgaccgtct gatagaagct aaaaaagaag atctgcataa tctgacaggt
      961 cctatgactg aagcccgcat tcgtcttcgt gaagaagtag ccgagcaaat caaggccctg
     1021 aaagagatta aagtattggg cgaatattat ggtttggatc tgagccgacc ggcatatacc
     1081 gcacaggaag ctgtacaatg ggtgtatatg gcttatctgg ctgccgtaaa agagcaggat
     1141 ggtgctgcca tgtcactggg taatgtatct tcattcctcg acatctatct tgaatatgaa
     1201 ttaagccagg gtacgataac cgaaacattc gctcaggaac tgatcgacca attcgttatc
     1261 aaactccgta tggtacgcca cttgcgtatg cagtcgtaca acgatatttt tgcgggtgat
     1321 cccacatggg tgaccgaatc tatcggtgga cgtttcaatg acggacgtac caaagttact
     1381 aaaacttctt tccgcttctt gcagacactt tataacttag gcccgtcacc ggaacctaac
     1441 atgactgtac tatggagccc tgagttaccc gaaggtttca aagcattctg tgcacaagta
     1501 tctatcgaca cttcttccgt acaatacgaa aacgacgacc taatgcgtga agtccgtcaa
     1561 tcggatgact acggaatcgc ttgttgtgtt tcatatcagg aaatcggaaa gcagattcaa
     1621 ttcttcggcg cacgtgccaa ccttgccaaa gccctgctac tggctatcaa cggaggacgt
     1681 tgcgaaaata caggtacagt tatggtaaaa gacatccctg tattgaccgg tgaaacactg
     1741 aagttcgaag aagtaatggc caactataag aaagtattga tacaaattgc acgtgtatac
     1801 aacgaagcaa tgaatatcat acattacatg cacgataagt attactacga aaaggcgcag
     1861 atggctttcg tggatactga tccccgcatt aacctcgctt atggtgtagc cggactttca
     1921 atcgccatcg attcactgtc cgccatcaaa tatgcacatg tgaaagcccg tcgcaacgac
     1981 atcggactga cggagggatt cgatatcgaa ggtgctttcc cttgtttcgg taatgacgat
     2041 gaccgtgtag accacttggg tgtggacctg gtatatttct ttagcgaaga attaaagaaa
     2101 ctccccgtat ataagaatgc ccgtcctacc ctttcgctgc tgactatcac ttcgaacgta
     2161 atgtatggca agaagaccgg tgccactcct gacggacgcg ccaaaggcat tgcctttgct
     2221 cccggtgcca accccatgca cggacgtgat aaaaatggtg caatcgcctc actgagttct
     2281 gtagccaagt tgcgttatcg cgactcacag gatggtatca gcaatacatt ctcaatcgtt
     2341 cccaaatcat tgggagcaac acaagaagac cgtatcgaca atctggtgac catgatggac
     2401 ggatatttta caaaaggcgc acaccacctg aacgtaaacg tgctgaaccg ggaaatgttg
     2461 caggatgcga tggaacatcc cgaaaagtat ccgcaactga ctatccgtgt ctcaggatat
     2521 gccgttaatt tcgtgaaatt gagccgcgaa catcagttgg aagtaatcag ccgcagtttc
     2581 cacgaaagaa tgtaattgaa tgataaacgt acactcatac gagtcaatgg gaacattcga
     2641 cgggccgggt ctccggctcg tcgttttcct tcaagggtgt aacttccgtt gcctctattg
     2701 tgccaatccg gacacaattg aagccaaagg agggacagca accgaccctg aggaaatagt
     2761 tcgcatggcc gtcagtcaga aagctttctt cggtaaaaag ggaggtatca ccttttccgg
     2821 cggagagcct acttttcaag caaaatcgct tatcccactt tttaaaagac taaaggaagc
     2881 aggaatccat atttgccttg ataccaatgg cgggctatgg aacaatgatg tagaggaact
     2941 attggaattg actgatctgg ttttattaga tatcaaagaa tttaatccgg aacatcatca
     3001 gtctttaacc ggaagaagca acgagcagac cctgaaaacc gcagcctggc ttgaaaccaa
     3061 tcataaacca ttctggttgc gatacgtatt agtgcccggc tacagtgact tcgaagacga
     3121 tatccggcag ctgggagagc atcttggaac gtaccagatg attcagcgtg tagaaatatt
     3181 gccttaccac accttgggtg ttcacaaata tgaagcaatg aacaaagaat atatgctgaa
     3241 aggagtgaaa gagaatactc cagagcagat agaaaaggct gagaaactat tcaggcaata
     3301 tttccagacc gtacaagtaa attgacttat ataagtgtcg aaactcgtat tcgccacaga
     3361 ttacacgaat ttacacagat aaagattcat tggccatcaa tagattaagt tcactctgcg
     3421 gtgaattatg acgactgcac ttatttataa ttttgtaagt cacgatataa aagtctccct
     3481 gttcttgcct taattcatta caatacaagg caagaacagg gagataatgt aaccggcata
     3541 ttttttgcca ccctacttta ataagtgaat cgcaatcctg cctgcaagtt aaagttacaa
     3601 ggcctttctt ttcggatggt ttgtactttg gagccatcat caaagaaata cgaaactccc
     3661 ggttccacat ataggccgac atgatctgtc gcattgaact gcgctcccac ggcaccggct
     3721 acagaaaatt gcaaaggctt cacattcacc ttatcatccg ccaactttcc ataaacacac
     3781 ttttcaacca ttcctccggc agatacatag agtgtaaaat atttcttttc cagaaaattc
     3841 cagtttccac gtacaggaat acctatataa tgcaatttct gactctgcat cttggtatcc
     3901 ccctgccgtt tgatatcaga agacaacaac gtataagtca atcccgtctc tacagagaaa
     3961 cctttgggaa gagacttacg tacagacagt ccgaagctaa ccggctgatg atgttcataa
     4021 tccaccacgg cagttgtatt ggacttcagg taaggaaccc cttcctcaaa tataacttcc
     4081 tgatcggcag gaatactcac agctccattc atgatcgtca tcaagtcgac cctgttagtc
     4141 atcggacggg gcgcaaaatt ttcggaacca tttgtcggaa gtccacctcc attaccgata
     4201 cccactccca tcgaccattt accaccacgt ttagcagaag agtctccgat aggcaactga
     4261 tacttgtctt taccggacgg tcgccgcgct tctttcctct ttggaggctg cgccgtcgca
     4321 ctttcttttt tctcgattgc agcaattgct tcctgttgcg gctcagatct cttttcctcc
     4381 gtcactgcct ccggtcgctt ctctaccagg gaggatacct ccggaacaat caccggatca
     4441 gtattctttg ccaaatagcc cgaaacaggg ttaatactcg tcgttcctac cggcttaact
     4501 ggttcggata cagctacctg tacatccggc aaggcaggtt ccggcaatac atccgggttg
     4561 acagccagtg aaggagccgt tgcataacgg atttcatcag ctaccgggct attcagaaaa
     4621 tacaaactga cagcagtcgt tagcaccaat accacagctg ccgcagcaac cgcccaccgg
     4681 cgatacggat atattcgttt ttcggttaca ggcatcagtt ccctttccag tcgttcccaa
     4741 ccggaagcag gcatcggctc cgaataatct tcgagcttat ccttgaatgc tttaatccat
     4801 ttttcgtctt ctttcatcat tctatttcat ttttgaaatc caaggttcac ctcagtatct
     4861 gtaaatacat gtcaaccatt ggtcaccaac cattctttca ctttctttgc caatacactt
     4921 tttgcgcgaa aaagctgtga ggcagaagat ttttcattaa tccccaacat ctgtgcgatt
     4981 tccttgtgcg acttatcttc aaaggtgtat aaattgaata cggtacgata tccggcgggg
     5041 agttcattaa taaattgcat cagcactttc tgtggtattg cttcaacagc cgaagcatcc
     5101 ggttcttcat acgtttcggg aacttcatcc agtgccgtgg tctggttcat cacgtcgttc
     5161 tttcttaaga actgtaaagc cgtattcacc attacacgct ccatccatgc tctcagagag
     5221 ccttcacccc gccaggtaaa cttgtcgaag gagtcgaaaa tcttcaggaa accgtcgtgt
     5281 accaagtctt gtgccatatc cctgtctccg gcataacgaa gacagacacc aagcatgcgc
     5341 cctgcgtact gctcataaag ttctttgcgg gcacgattat ctccctgcct gcaacgttcc
     5401 gacagctcta attcattcat tctcctaaac acgtgtttac cttataaatg cagcaaagat
     5461 agaaatactg cacagagaga acaactcttt tatcactttt gtttctttaa cattttagga
     5521 tgcaatatat catcacttcc tgcattttct caatacaata aagaataaat ctcaatggat
     5581 aaataggata aaaccaacaa gaaacttatg aagaaattta atttaataac ttttgccgtc
     5641 atcctgatgt tattgcccat tttacagtca tgtctggacg atgccaacaa cgacgagtgg
     5701 gtcacttgtc ctccgggtgg aatattggcc atcggcacaa tgaagattcc caatgcggac
     5761 actccaaggg actttttcat tgcgttggac aatggagaca atgtacttcc ggcagatacg
     5821 gccgatatac gcaacaggaa atacactgtt gcagaaggac aaagagtctt cgttggctat
     5881 ctgcagatgg gagaagagaa acctggatat gagaacggta aaatattcac gatagaagat
     5941 atattgacga aagagatcat cccactgacg gaagctacag cagacagcat tggagacgac
     6001 cgtatcaacg tcacagcgca tgcacttacg aaagattatc tgaccatcga atatcaatat
     6061 ctgggcagca tgaatgaaaa taaaaaacac atgctgaact tggtacaaaa cgaaataaca
     6121 ggtcccataa aagatgacgg atatatctat ctggagttcc ggcataatgc ctttaatgac
     6181 tcccccaatc aattgggttc gagccttgtt tctttcaagc tggatagtat agccgagcaa
     6241 ttggcgacag ccaaaggaat aaaactccgt gtgaacacca tttatgacaa tatacagtat
     6301 gtcacaatag atatcaacga agacaaaaac ttaaaaataa aatcatttca ttctcaataa
     6361 aacaacaaga aacacctaca caatcaggca aaacgagtaa taattctgat acataaaaga
     6421 aataaggcgg cgatgtttgt gaaaatatcg ccgtcgtttt tatattatac cagacactga
     6481 acggcctgca gggtaagcat ctccttggga accgccgcct gaatctcctc tttcaaaacc
     6541 tgcagcagac tggtgcggat gaagtctttc cgggtcacca ggacaatctg acgggtaggc
     6601 cgcgggatag caaacggacg gaccagttct ttctgctctt cgctcaattg catcactgcc
     6661 agttcgggaa taaacgtaat ccccttacca ctctccacca tatgcataaa ggtttccata
     6721 ctacccagcc gatacgccat ttggctgatc ttaaccgctt ccatctgaca aaaacgaacc
     6781 aactgatcgc ggaagcaatg cccttcgtca agaagccaaa gccgttcccc tgtcacatcg
     6841 gacgtacgaa tcacatcgtg cttgaacaac ggttccttct ttgagacata gcccaggaat
     6901 tgctcgtaaa ataaggtctc ttccgttaat gcggcatcat ccagcatgct ggcaatgata
     6961 gcagcatccg cttcaccggt cagcagagcc ttgcgaatgt cgggcgtctt cagctccatc
     7021 acccgtatat caagatccgg gtatttctcc atcagttgcg gaaagaaacg gggcagaaga
     7081 taaggtgcaa tcgtcggtaa cactgccaat cggaatgtac ccgacaggga gtgctgttct
     7141 tcgctgatga tctccttgac acagataact tccgaaagaa tcttacgggc ctgttccagc
     7201 actttcttac caatggcagt agggcaaacc ggtgtcatgc tacggtcgaa cagtttcacc
     7261 cccaattcgt cttccagctt ttggatcatt gcactcaaag taggttgcgt cacccggcaa
     7321 tactcggcag ctttagcaaa atgccggaac tggtccacag ccagaatata ttccaattgt
     7381 tgtatagtca tcgttctctg atttattaaa gatatagaat ctatcaatgc aaagatagaa
     7441 attttcagtt tgacacgaat cattttgtgc cgtatctttg ttccagataa aaagaagaaa
     7501 tatagtatta actcaaaaaa aacaatatca ttatgaagac tttaaattat acacatttgg
     7561 aagaaaaagg agctaacacc atcgtactgt cattacagca actgcttgcc gattttcaga
     7621 ttcattatgc aaacctgaga ggatttcact ggaacatcaa aggacacggt ttcttcgtac
     7681 tgcacagcaa gtttgaagat ttatataatg gagccgccga aaaggtggac gaaatagccg
     7741 aacgtatact gatgctggga ggaactcccg ccaataaata cagtgactat ctgaagatgg
     7801 cgcagatcaa ggaagtggac ggagtgaata aggccgacga cgctctgaat catattctcg
     7861 aaacttacgg gcatctgatt gcggaagaac gtaaaatcct gtctctcgcc tcttcacaca
     7921 acgacgaagt aacagtggcc atgatgagcg actacctgaa agaacaggaa aagatggttt
     7981 ggatgctgac tgcatacaac ggataacagc cgaaagggtg tagccatctg accgaaaagg
     8041 tgtagccata caaacaaaag ggtgtagcca tcccggcggg atagctacac cctttctgtt
     8101 ttattcgatt cagatgatac ttgtacgttt ggtaaattca ataatctccg gaatgtatcc
     8161 gaatgcgagc ccggtcactg tatccgcaca cccataatag atggcaatcc gtccggtctc
     8221 cgaatcatga agcgccgcgc atgggaaaca gacattaggc acatcaccca tacattcgta
     8281 atccttctga ggtgaaatca gataaggccc cgaacggaat tttactttcc agggctgatt
     8341 gatgtcaagc agtgccgaac caaaactata cacaaaaccg ttgcaggaag ccaatacacc
     8401 atgatagatc agtaaccagc cttccgaggt ttcaatcggg ataggccctg caccgatctt
     8461 ggtacactgc caggcactgt cttcgaacgg agccggcgac ataacatgac gatgacgtcc
     8521 ccagaactcc atatcgggag actcgctata gaaaatatct ccaaaaggag tatgcccatt
     8581 atcactcggg cggctcaaca tcgcaaaacg accgtttatc ttacgaggga acaagactcc
     8641 attccgattg aagggaataa aggcattctc caactggtga aaagtaacaa aatcataggt
     8701 gtaggccaca ccgatagtag gaccatgata gccattacac caggtcacat agtagcggtc
     8761 ttcgataaag caaacccgtg ggtcatatcc atagacccag gttccaacct cagcgtcatc
     8821 acattgaaac tttaacggtt cttcgttgat atcccaatga acagcatcct tactgaatcc
     8881 cacatgcaaa cgcatgcgac gattagtatc atcacaacgg aacacccctg catagccatc
     8941 cttaaacgga actacggcac tgttgaatat actgtttgaa gtagggagca agtcgcgcgg
     9001 aataatcgga ttggccgaac aacgccacac tacatcttta catcctgccg gacgttcttc
     9061 ccaaggcata gccggcaaag cagcacctgc aattttaatt tcttccatga ttcgattaaa
     9121 ttaatattat gtatatatct tgtttatatt gaaaatctct ttttatttct tctttccgtc
     9181 cggatatgtg aaaggtacca gccaagtcac gataaaagcc ggtatggtag cgataagtac
     9241 ccagataaag aaatcgcgat aacccagcca atcgctcagg tatccgctca tcattccggg
     9301 aagcatcacc cccagattca taataccggt agcaaaagca taatgtgcca tctgatgttt
     9361 gccgggagcc acttgctgca tcataaagag catcaatccg acaaaaccaa acccgtaacc
     9421 caagtattca gacacaatgg ccataccaat aatccataga tcggaaggct ggtaaagggc
     9481 taacaggaaa tataccaaga acggaatatt aaaagcgcaa cataaagaaa acaaagtctt
     9541 ccgaagtccg aaagccgaaa tgtaataacc ggccaaaagc gaaccgagaa taaaagctcc
     9601 cgctccgaac gtaccatata ccagtccgat atcctgagtg ctgagtccca atccaccatc
     9661 cgcaaccgac gctttcagga acaacggtac aatcttgatg gcatatcctt cggcaaaccg
     9721 gtacaaaatg ataaagacaa tgtagaaagc aatatgtttt ttttggaaaa aagagcggat
     9781 gacttcccaa agcatattca atgcgtcact catcgtattc acttcaccgg aagcgcctcc
     9841 tcccgaaggc aaaatccgga tgtggtaaag accgatcaga atcataatac ccgcacacat
     9901 caacatgaca atcatccagg catgtaccac tccaaattca tccttcagca tacctgccag
     9961 ccaaaccaag cctccgttgg caagtatctt ggccagatta taaaaagctc cctgccaacc
    10021 gatatacttg gcttgctggg tagcagtcag ttcagtcagg tatactccgt cacccgcaat
    10081 gtcatgagtc gcaccactga gagcaatgat ccccatcaga gcgatggcac aacgaaaaaa
    10141 gtcgggcagc ggcagcgaaa gtgctaccaa tgcaaatgcc agtccggtaa tgatttccgt
    10201 agcgacaaca aagtattttt tcgttttaaa catttccaga aacggactcc ataaaggctt
    10261 caatgtccag ggaagcataa tgagagaagt ccagaaagca atctgtgcat tcgacacttc
    10321 catatcggaa aacataagga cagaaaccat cgaaagggcc acaaacggca atcccatagc
    10381 aaagtaaaca gtaggcaccc aacatacagg gcttatcggc tttttattca tcagttagtt
    10441 ttttataata attccatcgg ttaacaattc cagtaagcaa agatagggga tattaaaaac
    10501 ataacccaag attacgacaa gaagttgctt tcattattta ataatacaac tcacccggga
    10561 aaactactaa cctctatcac ccttttttta ttaaacttta tcaatacaat acacgcaaag
    10621 aagcaccgaa gactttcatc cccgatgcct ctcgccccct tatctacaat ctaaacacct
    10681 ctattgcttc acatataaat ttatctcagc aaacccggta taattatccg gagtcagaca
    10741 gtttattctg aattccttta cattcgggat aggtggttcg atggccgcat attgcggatc
    10801 agccccttta aaatttctga aagtcaagac tctcgggtaa gtaacccact cggtttcacc
    10861 ctctttccga accttaatct cagcacttct cagattataa cccgatccgt aggcactctg
    10921 tttagtgacc gaaaatccgg ttaaggtaac aggccggtcc agtaccgtat tccaccaaca
    10981 ctctccggca ttagccactc cccatgtaaa ccaagtagta tttatctcac cgtcaatagc
    11041 cagatgtgca ccatatttgg catcatcatc ggcataaaca ttgctgcaac ttacactcca
    11101 cgcacttcga tctacagcgg accaattccc gggtttcgta taactggtat aaagcacgct
    11161 ggtataaatc cggatataaa ccgtcttcat agatgtactg acagcctgtt cgtccatgcc
    11221 cgtaactcct ttaagcgtca cgggaagcac atatccgcca ggattagtca acttttctat
    11281 attcttcaaa acgacctgaa aagatgaatc ggccactgtc tgtcccgttt ttaagacaac
    11341 ttcacttgtt tcaatggtat aattatcttg gggcaacaac ttacatttcg tcttattggc
    11401 agaattgtaa gtatccactt tcagcgtatc tactcccaaa gcggcagtgg catcccgcgt
    11461 aaccggctgt acggcacaca attgtatttc aaaatcagaa cggtcggcag tagaggaatt
    11521 gctcacacaa tccaccacta ccgcagcacc catttcggcc cccggtgcaa ctcccgttct
    11581 gatatatatc ttttgatatt tgtccatttc atcatcatcg ttgctgcacg aagccaacga
    11641 tacaaagcct gttatcaggc agattaaggt cacaaaattc aaatgtctat tcatatctta
    11701 tcttcttttt acatagttat tgcttatcaa aacgaacatg ctctttccag acaagagttc
    11761 ctcctgccac caaatcgtat ccgtgtccgg tacagtcggc aaaggcattt cctttacctt
    11821 catccatttt ccaatagcct atcaggttcg gatcggcggg tttcacggca aaatacatgt
    11881 tggactgaat ttgcgtctgg ctgattgcgc tcttccaaag acgcacctgg gccatctgac
    11941 aattgttgcg gaagtagcta ccgctcgaaa ccatgttcat cttgtcgaat cttaccgggc
    12001 caccctttgt ctgcagagtc acgtcgagca ctccgttgat ataaatcgac aataacccgg
    12061 aagaattata aacgaaggcc agatgatacc acttattctt ctcaaacaaa gtcaccgtat
    12121 tgacctgact tccaagtgtc ttcacctgta atgaattata agggatcata gcgtcaccga
    12181 aacggatata aacctcgtgg tcgctgctgc ccgaattaaa tatagcctga ttattaatat
    12241 cgaatccgtc catctgtacc caagcctcga gtgaccattc attggttgtc actccccaca
    12301 attcgtcctt ggcgggcttc acggcattgg tcgtattcat aaacggtaca gactgtatca
    12361 gcggcttatc cagcaaaatg ataaacttcg acgaaagccc gattgtagac accggtccct
    12421 gaatttctgt gagagatacc ggaatagcat acaattctcc gttttcgttt gaataaggtt
    12481 tcactctaaa ctcactgggg attgcgctaa catcgcctgc cgctatcttt atctctttgt
    12541 cataagtaaa atactgctcg ggaaggactt cgtacgaagt ttcattagct tcattgtact
    12601 ctttaagaat agaaggatct accgtcagga cagcagtcac attttcggtt acaggctgtc
    12661 ccacacgtac ggtcagagta gttgttgtta cattttcagg atcaacggta acctttgccg
    12721 aaccattctc ggatgcttca ttcaaataaa tcgcattgtc gataacctgg taatcggcat
    12781 cgttgcatcc tgccaggatc atcggcagaa cgaaacaggc aagcaaacat tgttttattg
    12841 ttattctttt cataatcaaa ttctttaaag tcattttaca gcaggattca ttattctgat
    12901 tgcttcacgc aggtacttat attcgatgtc gcccggatag tcatattcca tgtgataggt
    12961 gcctactcca cccttccgta cctgttttcc gtcaatagtc ggagtccagc gtgccatgcc
    13021 ggcaagtgct ctcattttgt ttccgtaacg atctacataa tcacctcctc ctgtcggagc
    13081 ataagattcg aaattctccg taacgatgta catattagcc actttctccg gaggaagtat
    13141 tcctttaaag ttggcaatcg taccagccag acgtctgtca agattagcgt cggaattacc
    13201 cgcaaggtta gagtatgcct gcacaatgaa atagtcaaag taaggcccgg tttccggatg
    13261 aatactttga ggctcgccat caatcacaag taaccgtccc gtacctgatt taggtccgat
    13321 tcttt
//
