LOCUS       gnlProkkaIIJOBCDP_60   11162 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IIJOBCDP_60.
ACCESSION   gnlProkkaIIJOBCDP_60
VERSION     gnlProkkaIIJOBCDP_60
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 11:47:08
            Original ID  :: gnl|Prokka|IIJOBCDP_60
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11162
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11162
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2611:6162]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2612..6162
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11162
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11162
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             2..133
                     /locus_tag="ctg60_1"
                     /transl_table=11
                     /translation="MLSPFLLGRSICLFTFFLQGFMDDDFVKSLLSGLFWIPWEGVG"
     CDS             123..1331
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 295.7; E-value:
                     1.1e-89)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_2"
                     /sec_met_domain="Bac_transf (E-value: 2.5e-69, bitscore:
                     223.0, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWDSRGIRPDQLVLRVLKNIIAFSIFWACIMTFSGISIYSPLFFV
                     AYFSFLFVILSIYRIIIRHFLIVYCAKGKHRRYAVFIGGGNNMQVLYEEMESSLASSLY
                     EVVGYFDIKPNEAFSSQCSYLGNPDGFSDFMSVHPGIKHVFCSLSMEEGRYNFSIMNHC
                     ENHLLYFHGVPNVCKGFPRRIWHSMVGNMPILNLRYEPLGKMENRILKRIFDIVISGLF
                     LVTIFPFVYLIVGSIIKLTSPGPVFFKQMRTGLNGVDFVCYKFRSMKVNDEADSKQATA
                     DDPRKTRFGDFLRRSNIDELPQFINVFKGDMSVVGPRPHMLAHTEIYARLIDKYMVRHF
                     IKPGVTGWAQTHGFRGETRELSQMEERVKADIWYMEHWTMLLDIYIIYKTVANVIVGEK
                     NAY"
     CDS             1393..2520
                     /locus_tag="ctg60_3"
                     /transl_table=11
                     /translation="MNHYDFLIVGAGLFGSVFAYKAKLQGKKCLVIDRRSHLGGNIYCE
                     NIEGINVHKYGAHIFHTSNKVVWDFVNSIVEFNRYTNSPIASYKGKLYNLPFNMNTFYQ
                     MWGITTPAEARAKIEEQKAEAIALMKEQGVIEPRNLEEQAQLLIGKDIYELLIKGYTEK
                     QWGRKCSDLPAFIIKRLPVRFIFDNNYFNDKYQGIPIGGYNVLIERLLEGIDTKLNYDF
                     FAHRNELEEISDRIVFTGAIDEFYRYRFGKLEYRTVNFETELLNMSNYQGNAVINYTEK
                     EIPYTRVIEHKHFEMFGADIEACSKTVISKEYSSEWKEGSEPYYPVNDEKNNSLYLKYK
                     KLADQDNNVIFGGRLAEYRYYDMHQIVTKALSHFK"
     CDS             2612..3925
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 200;
                     E-value: 7.8e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_4"
                     /sec_met_domain="CTP_transf_like (E-value: 2.7e-14,
                     bitscore: 44.2, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.7e-117, bitscore:
                     382.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.4e-61, bitscore:
                     198.7, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKIKTVYVGMSADIIHPGHLNIIHEANKLGRVVVGVLTDSAIAS
                     YKRLPYLSFEQRSLIVENLKGVDEVIPQTTLDYVPNLEKIRPNYVLHGDDWKEGVQQKT
                     RQHVIDCISQWGGKVIDIPYTQGISSSLLNQHLKEIGTTPEVRMKRLHRLIAAKPIVRI
                     LESHSGLTGLIAENACIEINNVKREFDGMWASSLTDSTSKGKPDIEAVDLTTRLHGLND
                     ALEVTTKPFIYDGDTGGKLEHFVFTVRTLERLGVSAVIIEDKVGLKQNSLFGTDAIQTQ
                     DTIEGFTAKIKAGKNAQITEDFMIIARCESLIAGKPMSDAIERCFAYVEAGVDGIMIHS
                     KEKTGEDIKEFCKKFRARYADIPIVVVPTTYNQFTEEELASWGINVVIYANHMLRASYP
                     AMMNCAKSILTHGRSKEASAEYCMPIKEILELIPSTHK"
     CDS             3935..5059
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 62.4;
                     E-value: 5.9e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.1e-20, bitscore:
                     64.5, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.4e-21, bitscore:
                     66.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPKFFIDELDRYGIDYFAGVPDSLLKSICGYIADNMDARHNII
                     TANEGAAVALAAGYHLATGKVGVVYMQNSGEGNAINPLASLVDKEVYNIPILLLIGWRG
                     CPGVQDEPQHVKQGKVTTGLLNIMGVNYDVLSKEENKAAKQILKAVEAVKRNEVYALII
                     EKDTFNAYTLQNVERNNFTMSREEAIQTVVAALGEADTIISTTGMISRELFEYRTAMNQ
                     GHERDFLTVGAMGHASQIALGIALEKQDRKVWCFDGDGASIMHMGSMAIVANKAPQNYV
                     HVVFNNGAHDSVGGQPTVGLKIDIPAIAKAMGYKHVYNVDTKEGLQELIGEIKVQEGPI
                     FLQACVKQGNRKDLGRPTTTPIQNKEALMTFLRS"
     CDS             5071..6162
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_6"
                     /sec_met_domain="Fe-ADH (E-value: 1.7e-67, bitscore: 218.3,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIIYQGIDYLNEALKGSTKVLLVCGSSFPYLGIKDKIEHIGTPF
                     MVFDQFTSNPLYEDICRGVDLFQITQCDTILAIGGGSSMDVAKCVKLYCQMSKDKPYLQ
                     QEYKDTGVKLIAIPTTAGSGSESTCYAVIYHDGKKQSVMHKSIIPDVVILEPKLLKTLP
                     VYQKKCTMLDALCQGIESWWSVNSTDESKRYSKIAVETIIKYWREYIFENTDFSAEQIM
                     LAANYAGRAICITQTTAAHAFSYKITSLYKLPHGHAVAVGLSEIWEYMLLNMNKCLEPR
                     GEEYLWGIFADISKAMGCLTLEQAVVKFRQILTEMEITNPVAINKTEEIEILSHSVNPV
                     RLKNNPVELCEFTIKSLYEIIIK"
     CDS             6238..7218
                     /locus_tag="ctg60_7"
                     /transl_table=11
                     /translation="MTQYINSLEEEMRSGFLVTRQSKHVWNIQIEMTLALLEVCKKYNL
                     RIWAISGTMLGAVRHKGFIPWDDDMDFFMFREDYDRLLEIASDEFKKPIFFQCAYTEKG
                     YYRGHAQMRYDNTAMILLYEGEIGVKFHQGIFIDIFVADGFPEDKEEREQLIEQRNCIL
                     NYLWGRNYPLRRFSSIPNLIKYISAKRKLGEKASWTDIELYSYMEQLHRNYSVNRNSRN
                     CCIQFTYLPRYVRNTEWFDETVWIPFERIELPVPLAYHEVLKHEYGDYMKPIKGASLHG
                     NLVVDVDESYEKYLSGLKMSFLKATYLFIKSGGGMVLRVFGLRKK"
     CDS             7243..8670
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_8"
                     /sec_met_domain="Polysacc_synt (E-value: 1.4e-39, bitscore:
                     126.8, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDKAVNGVFWTSVERIGSQVLSLLVGIAVARILSPEDYGIIGMT
                     AIFLAVASTLLDSGFGSALIQNQNRTETDYSTCFYFNIVVGLFWYVVLFLAAPLIADFY
                     RTPLLESVCRVLGLVFVFNSLTISQTARLTVEFRFRELCFVTLGTQLLTGIVGFIMAFK
                     GYGVWALVFQQVGAAFLRVCLIEWITHWKPLPLFSKIAFCRMFSFGSKILCSGIINTVY
                     DNIYTLVIGRVFSPVEVGFYNRGNQFAQLPSQSLLSVVMKVVYPLMAEVQDDSEKLCRA
                     YQKFLRISVFILYPILIGLIVLAESFIYVLLGDKWLPCVPLMQILCFSYLFDPLTHINL
                     NILYVRGRTDLVLKLELIKKPIALIILFGMLPFGLWWLCAGRALYSFIAYCFNCFYTGK
                     FIRFGFRQQMYYSVPVIVKSALMGIICWRTALGFEEPWLKLMVGFLAGLLSYIGLNFIS
                     HDESFFDIKGIILKNGK"
     CDS             8667..9701
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_9"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.3e-27,
                     bitscore: 87.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINNIIMNKILSVVIPSYNMEEYLYRNVSSMMIGEILDDLEIIIV
                     NDGSKDRTSEIAHELQRKASQSIVVIDKENGHYGSCVNAALKIATGKYFRILDADDWMD
                     SGEFVKFVNILKCIDVDCIYTPFANVFFNKNRKEYCIADNAVWNKKIDLSHVSLPPSYF
                     HMHSLTYRTHLLHKISFVQEEKICYTDSEYVFYPLSHAKSLYCINVCPYQYYIGREGQS
                     VSLDSLSKNYAHFEKVLANISFYKPMELLPTYSSLRKYYIVTLLRYMLDIHLFSQKKDV
                     QRDKLLRDKIRAFGDDVNISEQIKDINLKGLHYINWWLDNTGVDKLKLKILVLLKKVQH
                     TIVN"
     CDS             9703..10668
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_10"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.7e-28,
                     bitscore: 88.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKISVIIPVYKVEQFIERCAISLFEQTLDDIEYLFIDDCSPDNS
                     VEIIKNVLMRYETRKDSVRIISMQKNCGQAAVRRYGNSIARGDYIIHCDGDDWVDINMY
                     YKMYECAVNNKLDIVRCKFCRTDGKLMKECINIPSNIYCDAKKMISYLLRLSDLSSTCD
                     KLVRRELYQSVDFIYPVDNMCEDFAIVTQLFCRTDKIGYIDEVLYFYYQNKFSISHILD
                     NTHIDNKAQQISNNVKLIGKILKTKYPGGIFDKEIEVIKLMAKNAYRPIIRREGYYEKW
                     KTLYKEINSKIFFNEYITIKEKLSFIACYIGIYPLLTGRK"
ORIGIN
        1 tgttctttct ccttttcttt tgggaagaag tatttgtctc tttacctttt tcttgcaggg
       61 tttcatggat gatgacttcg ttaagtctct gctatctggc ctgttctgga tcccgtggga
      121 gggtgtggga tagtcgggga attcgccctg accaacttgt gttgcgtgtg ttgaagaata
      181 ttatagcttt ttccatcttt tgggcatgta tcatgacttt tagtggaatc tctatctatt
      241 ctcctctttt ctttgttgcc tatttctctt tcctctttgt tattctaagc atttatcgca
      301 ttattatccg tcatttcctg atagtctatt gtgctaaagg caagcataga cgttatgctg
      361 tttttatagg tggaggcaat aatatgcagg tgttgtatga ggagatggag agttctttag
      421 cctcttccct atatgaggtt gtgggttatt ttgatataaa accgaatgaa gccttttcct
      481 cccaatgttc ctatctgggt aatcccgacg gtttttcaga ctttatgtcc gtacatccgg
      541 gaatcaaaca tgttttttgt tctctgtcga tggaggaggg gcgctataat ttttctatta
      601 tgaatcattg tgaaaaccat ttgctttatt ttcatggtgt tcctaatgta tgtaaaggtt
      661 ttcctcgtcg tatctggcac agtatggttg gcaatatgcc tatcttgaat ctgcgttatg
      721 agcctttggg taaaatggaa aatcggatat tgaagcgaat atttgatatt gttatctcag
      781 gtctttttct ggttactatt tttccttttg tttatctcat agtgggaagt attataaaat
      841 tgacttctcc cggtcctgta ttctttaagc aaatgcgtac gggtttgaat ggtgtggatt
      901 ttgtgtgtta taaattccgt tcgatgaaag tgaatgatga agccgacagt aaacaggcta
      961 cggctgatga tccccgtaaa acaagatttg gagatttcct ccgtcgttct aatattgacg
     1021 aactccctca gtttatcaat gtctttaagg gtgatatgtc ggtagttggt ccccgtccac
     1081 acatgttagc ccatacggag atttatgccc gtttgattga taaatatatg gtgcggcact
     1141 ttataaaacc tggagtgacc ggttgggctc aaacgcatgg ttttcgtggt gaaacgaggg
     1201 aattatcaca gatggaggaa cgtgttaagg ctgatatctg gtatatggag cactggacaa
     1261 tgctgcttga catatatatc atttataaga ctgtggcgaa tgtgattgtg ggggagaaga
     1321 atgcgtatta gaagagggga tattaacgaa tttaaatgta tttcgtaata tagaaataaa
     1381 attagaaatg tcatgaatca ttacgatttc ttaatagtag gtgccggact ttttggttcc
     1441 gtattcgcct ataaagcaaa actacaaggt aaaaagtgtt tagttattga tcgccgttct
     1501 catttgggtg ggaatattta ttgtgaaaac atagaaggta ttaatgttca taaatatgga
     1561 gcacacattt ttcatacttc caataaagta gtgtgggatt ttgtaaattc cattgtggaa
     1621 ttcaatcgct ataccaattc accgatagct agctataaag gaaagctgta taatttacct
     1681 ttcaatatga atactttcta tcagatgtgg ggaatcacta ctcctgctga agcaagggca
     1741 aagattgaag aacagaaggc agaggcgatt gctctcatga aagaacaagg tgttattgaa
     1801 cctcgcaact tggaagagca ggcacagtta cttatcggaa aggatattta tgaattgctg
     1861 attaagggtt atacagaaaa acagtgggga cgcaaatgta gcgatcttcc cgcattcatc
     1921 atcaaacgac ttcctgtacg ttttattttt gataacaact attttaacga taaatatcag
     1981 ggaattccta tcggtggata caatgtactg atagagcgct tgctggaagg tatagatacc
     2041 aaactaaact atgatttctt tgctcaccgg aatgagttgg aagaaatttc agataggata
     2101 gtatttacag gagcaataga tgagttttat agatatagat tcgggaagtt ggaatatcgt
     2161 acagtaaatt ttgaaacgga gctattaaat atgtccaact atcagggtaa tgcagtaatt
     2221 aattatacag aaaaagaaat tccctataca cgtgtcattg agcataagca ttttgaaatg
     2281 ttcggggcgg acattgaggc ttgttctaaa actgttatct cgaaggaata cagttcagaa
     2341 tggaaagaag ggagcgaacc ttattatcca gtaaatgacg aaaagaataa ttcgctttat
     2401 cttaaatata agaaactggc tgatcaggat aacaatgtga tttttggagg tcgattggca
     2461 gaatatagat attatgatat gcatcaaata gtaacaaaag ctttaagcca ttttaaatga
     2521 aggcatatgt taatatatct aatttttgaa ggtgtatttt tatgtgatta aatataaaaa
     2581 aactgtctat atagtattat aattcaataa tatggataag ataaaaactg tttatgtcgg
     2641 tatgagtgct gacataattc acccggggca tctcaacata attcatgagg caaataagct
     2701 tggtcgtgtt gtggtagggg tattaacgga ttcggcaata gctagttaca agcggttgcc
     2761 ttatctgtca tttgaacaac gttcacttat tgttgagaat ctgaaagggg tggatgaagt
     2821 catacctcag actactcttg attatgtacc gaatttggag aaaatccgtc caaattatgt
     2881 tcttcacggt gatgattgga aagagggggt tcagcagaag acgcgtcagc atgttatcga
     2941 ttgcatttca caatggggag gtaaggttat agatattcct tatactcaag gtatttcttc
     3001 ttcattgctt aaccaacatc tgaaagagat aggtacaacc cctgaagtcc gaatgaaaag
     3061 acttcaccgg ctgattgctg ctaagcctat tgtacgtatt cttgaaagtc attcaggact
     3121 tactggtctt attgcggaaa atgcttgcat tgaaattaat aatgtgaagc gtgagttcga
     3181 cggtatgtgg gcatcttcat tgaccgattc tacctcaaag ggtaaaccgg atatagaggc
     3241 tgtcgacttg acgacacggc ttcatggtct taacgatgct ctcgaagtaa ctacaaaacc
     3301 gtttatttat gatggtgata ctggtggaaa attagagcat tttgttttca ctgttcgcac
     3361 tttagaacgt ctgggagttt ctgctgttat cattgaggat aaagtgggat taaagcaaaa
     3421 ttcactattc ggtacagacg ctattcagac acaggatact atcgaaggat ttacagcaaa
     3481 gattaaggcg ggcaaaaatg ctcagattac tgaagacttt atgattatag cacgttgtga
     3541 atcgcttatt gcaggtaagc caatgtctga tgctattgag cgttgctttg cttatgtgga
     3601 ggctggtgtt gatggtatca tgattcattc aaaggaaaaa acaggtgagg atatcaagga
     3661 attctgtaaa aaatttcgtg caagatatgc ggatataccc attgtggttg ttccgacaac
     3721 ctataatcag tttacagagg aggagttggc ttcatgggga ataaatgtgg taatatatgc
     3781 aaatcacatg cttcgtgcat cttatccagc aatgatgaat tgtgccaagt ctatcttgac
     3841 acatggtcgt tcaaaagagg cttctgcaga atactgcatg cctatcaaag agattcttga
     3901 actcatccct agtacacata aataaaataa tataatgatt agtccgaaat tttttataga
     3961 cgaattggat aggtatggta ttgactattt tgcaggtgta ccggattcgc tactgaagag
     4021 tatctgtgga tacatagccg acaatatgga tgctaggcac aacattataa ctgctaatga
     4081 aggtgctgct gttgctcttg cggctggtta tcatttagcc acaggaaagg taggtgttgt
     4141 atacatgcag aactctggtg agggaaatgc cataaatcca ttggcttcac tagtagataa
     4201 ggaagtctat aatataccga ttcttcttct gattggttgg cgtggttgtc ctggggtgca
     4261 agatgaacca caacatgtaa aacagggcaa ggtgacaacc ggattgctta atattatggg
     4321 agtgaactat gatgtgcttt caaaagaaga aaacaaggct gcaaagcaaa tattaaaagc
     4381 tgtagaggcg gttaaacgga atgaggtcta tgcccttatc attgaaaaag acacctttaa
     4441 tgcctatact cttcaaaatg tagagagaaa taattttacg atgtctcgtg aagaggctat
     4501 tcaaacagtt gtagcagcac ttggtgaagc tgatactatt atatctacta caggtatgat
     4561 aagtcgtgaa ctcttcgagt accgtactgc tatgaatcaa ggacatgagc gcgatttttt
     4621 gacagtaggg gctatgggac atgcctctca aatagcttta ggcatagctt tagagaagca
     4681 agatcgcaaa gtgtggtgtt ttgatggtga tggagcttct attatgcata tgggtagtat
     4741 ggctattgtg gctaataaag cgcctcagaa ctatgttcat gtagttttta ataatggtgc
     4801 tcacgactcg gtcggaggtc agcctactgt aggtttgaag attgatatac ctgctatagc
     4861 taaagctatg gggtataaac atgtttataa tgtcgataca aaggaggggc tacaagaatt
     4921 gattggtgaa atcaaagtcc aagaaggacc aattttcttg caggcatgtg tcaagcaggg
     4981 caatcgcaag gatttaggtc gtcccactac tacacctatt cagaataagg aagctctgat
     5041 gactttttta aggagttaga tttatataat atgcaaataa tatatcaagg aattgattat
     5101 cttaatgaag ctctcaaagg ttctaccaag gtgctattag tttgtggtag tagctttcct
     5161 tatcttggta ttaaggataa gatagaacat attggtactc ccttcatggt gtttgatcag
     5221 tttacttcta atcctcttta tgaagatatc tgtagggggg tagacctttt ccagattact
     5281 caatgcgaca caattcttgc tattggtggt ggtagctcaa tggacgtggc taaatgtgta
     5341 aagctatatt gtcaaatgtc aaaagataag ccctatttgc agcaagagta caaagatact
     5401 ggcgtgaaac tgattgccat tcctactacg gcaggttcag ggtctgaatc tacctgctat
     5461 gccgttattt atcatgatgg taagaaacag agcgtgatgc acaaaagtat tattcctgat
     5521 gtcgtcattc ttgaaccaaa gttgctcaag actcttcccg tttatcagaa gaaatgtact
     5581 atgcttgatg ctctttgtca aggtattgaa tcttggtggt ctgtgaactc cactgacgag
     5641 agcaagcgtt attccaagat agctgttgag acaatcataa agtattggcg tgagtatatt
     5701 tttgaaaata cagacttttc agctgaacag atcatgttgg ctgctaacta tgctggtcgt
     5761 gccatttgca taactcaaac tacggccgca catgctttca gttataagat tacttctcta
     5821 tataaacttc ctcatggtca tgctgtggca gtaggacttt cagaaatatg ggaatatatg
     5881 ttgttgaaca tgaacaaatg tttagaacct cgcggtgaag aatatctttg gggcatcttt
     5941 gctgacattt ctaaagctat ggggtgctta actttggagc aagctgttgt caagtttcgc
     6001 caaatattga cagaaatgga aatcacaaac ccggttgcta ttaataagac agaggagatt
     6061 gaaattcttt cccattcagt taatcccgtt aggctgaaga ataatcctgt ggaactttgc
     6121 gaatttacta ttaagtctct ttatgagatt attattaaat agatatctat gagtttattc
     6181 aatgaataag gagtattaag tgatgatcta aaataatagc cgtttactta cacttttatg
     6241 acacaatata taaattcgct tgaagaagag atgcggagtg gttttttggt tacgcgtcaa
     6301 agcaaacacg tatggaatat acagatagaa atgacattgg cacttcttga ggtatgtaaa
     6361 aaatataatc ttcgtatatg ggcaataagt ggaacgatgc tgggagctgt gcggcataaa
     6421 ggatttattc catgggatga tgatatggat ttttttatgt tcagagaaga ttatgaccgt
     6481 ttattagaaa tagcttcgga tgaatttaaa aaacctatat tctttcagtg tgcttatact
     6541 gaaaaaggat attatagagg gcatgctcag atgcgttatg acaatacagc tatgatattg
     6601 ttatatgaag gagaaatcgg cgttaaattt catcagggga tatttataga tatatttgta
     6661 gctgacggat ttcctgaaga taaagaagaa agagaacaac ttatagaaca gagaaactgc
     6721 attctaaatt atttatgggg aagaaattat cctctgagac ggttctcttc cataccgaat
     6781 ttgataaaat acatttctgc taaacgaaag ttgggggaaa aggcttcgtg gactgatatt
     6841 gaactttatt cttacatgga acaacttcat cgtaactatt ctgttaacag aaattcaagg
     6901 aattgttgta ttcaatttac ttatttgcct agatatgtga gaaatacaga atggttcgat
     6961 gaaacagtct ggataccatt tgagagaata gaattgcctg ttcctttggc atatcatgaa
     7021 gtgttgaagc atgaatatgg tgattatatg aaaccgatca agggggcgag tcttcatggt
     7081 aatttggtgg tagatgtaga tgaatcttac gagaaatatc tttcaggtct gaagatgtct
     7141 tttctaaaag ctacatattt gtttataaag tcagggggcg ggatggtgct tcgtgtattt
     7201 ggtttgagaa aaaagtaaat ttaggatagc ggcgactacg ttatgaaaga taaagctgtc
     7261 aacggtgttt tttggacttc ggtggaaaga attggtagtc aggtgcttag tcttcttgta
     7321 ggaatagcag ttgcgaggat tctatctcca gaagattatg gtataatagg aatgactgcc
     7381 attttcttag cagtagcttc tactcttctt gacagcggat ttggtagcgc actaatacaa
     7441 aatcaaaata gaacagaaac tgattattct acttgctttt attttaatat agttgtaggt
     7501 ctgttttggt atgtagtatt gtttttagca gctccgctaa tagcagactt ttatcgtacg
     7561 ccattgctgg aatcggtttg cagagttcta ggtttggttt ttgtattcaa ttcacttaca
     7621 atttcgcaga cggcacggct taccgtagaa tttagatttc gggaactgtg tttcgttaca
     7681 ttaggtacgc agttgttaac gggaattgtt ggtttcatta tggcatttaa aggttatgga
     7741 gtatgggcgt tggtgtttca gcaagtaggc gcagcttttt taagagtatg tctgatagaa
     7801 tggattacac attggaaacc gttacccttg ttttccaaga ttgcattttg tagaatgttt
     7861 tcatttggtt ctaaaatact atgttcaggc attataaata ctgtttatga caatatctat
     7921 acattagtga tagggcgtgt cttttcacct gtagaagttg gattctataa tagaggaaat
     7981 cagtttgcac aattaccatc tcaaagtttg ctatctgttg ttatgaaagt cgtttatcca
     8041 ttgatggcag aagtgcaaga tgattcggaa aaactttgta gagcttatca gaaatttttg
     8101 cgtatttcgg ttttcattct ttatcctatt cttattgggt taatagtctt agcagagtct
     8161 tttatttatg tattgctagg cgataaatgg ttgccttgtg ttcccttgat gcaaatatta
     8221 tgttttagct acttgtttga cccacttaca catataaatc ttaatatttt gtatgtaaga
     8281 ggacggactg atttagtact taaactagaa cttataaaga aaccgatagc attgattatt
     8341 ttgtttggaa tgctaccatt cgggttatgg tggctgtgtg caggacgtgc tttgtacagt
     8401 tttatagcgt actgctttaa ttgtttttat actggaaagt ttattagatt tggttttagg
     8461 caacagatgt actatagtgt acctgtgatt gtaaaatctg ctttgatggg gattatttgt
     8521 tggagaacag cattaggctt tgaagaacca tggttaaagt tgatggtagg atttttggca
     8581 ggattgcttt cttatatagg actgaatttt ataagtcatg atgaaagttt ttttgatata
     8641 aaagggataa tattgaaaaa tgggaaatga taaataatat aataatgaac aaaatattat
     8701 ctgtagttat tccttcgtat aatatggagg agtatttgta ccgaaatgtg agtagcatga
     8761 tgattgggga aatattagat gaccttgaaa tcattattgt taatgacgga agtaaggata
     8821 gaacgtctga aatagcacat gaacttcaaa gaaaagcttc tcaaagtatt gttgttattg
     8881 ataaggaaaa cggtcattat ggttcatgtg taaatgcagc gttgaagata gcaacaggca
     8941 aatattttcg aattttggat gcggatgact ggatggatag cggtgaattt gtaaaatttg
     9001 taaatatatt gaagtgtatt gatgtagact gtatctatac accttttgcg aatgtttttt
     9061 ttaataaaaa tagaaaggaa tattgtattg ctgataatgc agtgtggaat aaaaagatag
     9121 atctgagtca tgtctcattg cccccttctt attttcacat gcactcattg acttatcgga
     9181 ctcatttgtt acataaaata agttttgtgc aggaagaaaa gatttgttat acggattcag
     9241 agtatgtttt ttatcctttg tctcatgcaa aatcgttata ctgtattaat gtttgccctt
     9301 atcagtatta tataggtcgc gaaggacaat ctgtatcatt ggattctttg agtaaaaact
     9361 atgctcattt tgagaaagta ttggcaaata tcagttttta taagcctatg gaattgttac
     9421 cgacatattc atcacttaga aaatattata ttgtgacgct gctacgttat atgcttgata
     9481 ttcatctttt ttcacagaaa aaggatgttc agagagacaa gctattaaga gacaaaataa
     9541 gggcttttgg tgatgacgtt aacattagtg aacaaattaa agacatcaat cttaaggggt
     9601 tgcattatat taattggtgg ttggataata caggtgttga taaattaaaa cttaaaattc
     9661 ttgtcttatt aaaaaaagta caacatacaa tagttaattg aaatgcctaa aattagcgta
     9721 ataataccgg tgtataaagt agaacaattt atagaaaggt gtgcaattag tcttttcgaa
     9781 caaactttag acgatattga atatcttttc atagatgatt gttcacctga taattcagtg
     9841 gagattatta aaaatgtttt gatgcgatat gaaacaagaa aagattcggt tcgtattata
     9901 tctatgcaaa agaattgtgg acaagctgct gtgcgtagat atggcaatag tatagctcgt
     9961 ggtgattata taattcattg tgacggagac gattgggtgg atattaatat gtactacaaa
    10021 atgtacgagt gtgctgtcaa taataagtta gatattgtca ggtgtaaatt ttgtagaaca
    10081 gatggaaagt taatgaaaga atgtattaat atcccaagta atatatattg tgatgcaaaa
    10141 aaaatgattt cctacttgtt aaggttatct gatttatctt caacttgcga taaattggta
    10201 agacgggaac tttatcaatc agtagatttt atatatcctg ttgataatat gtgtgaagat
    10261 ttcgcaattg taactcaatt gttttgtcgt actgataaaa ttggatatat agatgaagtt
    10321 ctctattttt attatcaaaa taaattttca ataagtcata tattggataa tactcatata
    10381 gataataagg cacaacaaat aagcaataat gtaaaactga taggaaaaat tttgaaaaca
    10441 aaatatccag gtggaatttt cgataaagaa attgaagtaa ttaaattgat ggcaaaaaat
    10501 gcctatagac ctattataag aagagaaggg tattatgaaa agtggaaaac attatataag
    10561 gaaataaatt cgaaaatatt tttcaatgaa tatataacaa taaaagaaaa attgtcattt
    10621 atagcttgct atatcgggat atatcctttg ttgactgggc gtaaatagta aatatgggaa
    10681 atatagaaaa ttgtatatat ttaattactt tgtttttgtt tgagatatta ttatttcttt
    10741 atgtatggca gaagtttgat agatctattt tttctccatc aatatatact atcggtgttt
    10801 taggatttgg aacattgctg aatatttggt gtgttgatta ttgggatatt agttttcatc
    10861 cacgtacatt tggaattata gctttaggat tatgcatgat ggttattgct gaaaaaaatg
    10921 cttatataaa aagacgtaat gatagtgaat ataagatgtt ttatatttct ttacctccta
    10981 tgttagttat ctctgtggct gcatattgca ttgtagcaac atttttgtat tttaatgaaa
    11041 tacgtagatt ggggttagcg caatctttgg cggtttcaga agcgataggt aatataaagg
    11101 aaaattttga ggaatttgaa gaattattta acccatttat tcggcaagga tataaaatag
    11161 tt
//
