LOCUS       c00071_gnlPro..        11026 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MBIHEHPF_71.
ACCESSION   c00071_gnlPro..
VERSION     c00071_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:33:08
            Original ID  :: gnl|Prokka|MBIHEHPF_71
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11026
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11026
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2539:6822]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2540..6822
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..11026
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11026
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1068..2537
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_1"
                     /sec_met_domain="OKR_DC_1_C (E-value: 4.7e-13, bitscore:
                     38.9, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 2.9e-124,
                     bitscore: 403.9, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGSRFKLNQNHAPIHEALETFRRMRVVPFDVPGHKRGRGNPELT
                     EFLGQKCVGVDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSSVQTMV
                     LTACKRGDEIILPRNVHRSVLNALVLCGAIPVYVNPEVDQRLGISLGMRREQVEKAIKE
                     HPKAVAVLVNNPTYYGICSDLRAIVKMAHDAGMLCLADEAHGTHFYFGGGLPVSAMAAG
                     ADMASVSMHKSGGSLTQSSLLLTGPNVHAGYVRQIINLTQTTSGSYLLMSSLDISRRNL
                     AQRGRQIFHQVADMAEYAREEINAIGGYYAFGKELVNGNSVFDFDITKLSVHTLDIGLA
                     GIEVYDILRDEYDIQIEFGDIGNILAYLSIGDRAQEIERLVSALAEIRRRFQTDGSGLL
                     SQEYIDPQVVTSPQEAFYADKCSLPLRETEGKVCSEFVMCYPPGIPILAPGERITAEIL
                     DYIEYAKAKGCNMTGPEDPDILRLNVLAGRE"
     CDS             2540..3394
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_2"
                     /sec_met_domain="Spermine_synth (E-value: 2.1e-54,
                     bitscore: 173.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 9.6e-23,
                     bitscore: 69.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEMWFSEFHTPDVKHSIRVNRQLYSKQSDYQRIDVFETPEFGRVL
                     TLDGNVMLTERDEFIYDEMITHVPMAIHKEARDILVIGAGDGGVVRELTRYDRVRHIDL
                     VEMDPMVVEACRAYLPGNACRLDDRRVHLHYENALRFIRRCEAKYDLIIVDSSDPFGPS
                     EGLFTREFYGNCYNALKDDGIMVNQQGSPFYAEDAHAMQRSHKRIASTFQISRVYQAHI
                     PTFAAGYWLFGFASKKYHPVDDLDAEAWNALNLRTRYYTTRLHKGAFYLPAFLEDMLKE
                     VEE"
     CDS             3398..4255
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_3"
                     /sec_met_domain="Arginase (E-value: 4.6e-78, bitscore:
                     251.7, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILPNIETFIGCESSFEEASIVLYGAPFDSTTSFRPGARFGPAAM
                     RHESFGLETYSPYQDRDLMDIRVFDSGDLELCFGSSEMALSDIEKRAEEILNAGKFPLL
                     LGGEHLVTLAAVRAAAAKYPNLHIIHFDAHADLRDDYLGAKLSHACVLRRCHEILGDDH
                     IHQFCIRSGEREEFQFARKHTDFHPFTFEGLKETVRELKEKQVPVYFTIDLDCLDPSVF
                     PGTGTPEAGGVSFMELLEAIRMVSQANVVGADVNELAPMLDASGVSTATACKVLRELLL
                     AIAK"
     CDS             4349..5608
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_4"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1e-44, bitscore:
                     142.8, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1e-33, bitscore:
                     105.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRVLVIGCGGVASVAIQKCCQVDEVFTEMCIASRTKEKCDALVE
                     KLKGKTKTVLTTAKVDADDVDQLIELINSYKPDLVMNIALPYQDLTIMDACLACGVNYM
                     DTANYEPEDTDDPEWRAIYEKRCKEEGFSAYFDYSWQWAYRKKFEDAGLTALLGCGFDP
                     GVTQAYCAYALKHEFDQIDTIDILDCNGGDHGYAFATNFNPEINLREVSAPGSYWENGH
                     WVEIPPMDIKREYNFDQVGDKDMYLLHHEEIESLAKTIPGVKRIRFFMTFGQSYLDHMR
                     CLEDVGMLSTTPIQYNGQEIVPIQFLKALLPDPASLGPRTKGKTNIGCIFTGVKDGKEK
                     TYYIYNVCDHQECYHEVGSQAISYTTGVPAMCGALMMLTGKWIRPGVYTVEEFDPDPFL
                     DALDRYGLPRSESHDPKLVD"
     CDS             5608..6822
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_5"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 2.6e-16,
                     bitscore: 49.0, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGLDKRAPFTATGGMIPPEFRNIKTPCYILDEKALIKNAKLLGE
                     VAERTGCKMLLAQKAFSNYDCYQFFEPYLAGTEASGLFEARLGAEEMPGKEVHVFCAGY
                     RADEFEDLLQYADHIVFNSPSQLLRFGQRAKEARKSVGLRINPECSTQEGHEIYDPCAP
                     GSRMGTTRAQWDEAFQKNPELLDLLDGLHFHTLCEQDSDDLETTLISVKKHFGDLASRV
                     KWVNFGGGHHITRPGYDIERLERCIRMVQEEWKVDVYLEPGEAWALNAGFLLTRVLDVL
                     KNGETEIAIVDASAACHMPDVLEMPYLPPLLGADDIEERGTTVRLGGPTCLSGDVIGDY
                     KFRQFPEYGDLLMFGDMAIYTTCKNNTFNGMPLPDIWLRRADSTMQQLTDFGYGDFKGR
                     LGSRK"
     CDS             6931..8004
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_6"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5e-25, bitscore:
                     77.5, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTISLCMIVKNEERVLGRCLESVQEIADEIIIVDTGSEDRTKKI
                     AEKYHARVFEQEWQDDFSRARNYSFSQAEMDYCMWLDADDIITKSEVLKLKRWKEETDG
                     SSDVVMIRYVAGFDEKRNPTLVYYRERIVKRDKDFQWQGRVHETLAVRGRTEYLDCEIE
                     HHSIKTEYSRRNLEIYQKMESDGEVLSARDRFYYGRELFYHREYVEAVDNLLKFLQLPE
                     GFVENQVEACRVAARCCYELKQNGMALEFLYRGLTYRTPSGELCCDIGKHFFDRKKWEQ
                     AVFWYRNALQVSENAKTGGFVEKECYGYIPCIQLSVCWYYLGDIEKAFQYHCQAGTYKP
                     YGREFLKNQQYFISVKQ"
     CDS             8311..8619
                     /locus_tag="ctg71_7"
                     /transl_table=11
                     /translation="LQGPQGIQGPAGAQGATGPQGIQGPIGVTGATGPAGPQGSPGATG
                     PVGADGPVGATGPTGPTGPAGTITPAAAVANATSAEDVVNQFNLLLANMRTAGLLAE"
     CDS             complement(8876..10195)
                     /locus_tag="ctg71_8"
                     /transl_table=11
                     /translation="MTDILCPVLELSVIIPGILLAYLPVKSYLRQTPLKLTAWLLPLLL
                     GICILGGAVCCALQIPTRWFLFPLLPVIMLIYHKTLKISVWKSVSIFLAVFAVFTCIKS
                     LSRALNALMTADLHIAENELWLHTGAGIFYNVICLLFVLAVWYPACHYVQTMIADENFA
                     QTWYVFWILPVIFIGMNLFMIPKYRSTLYTGRVLQCYIVLSLVLLIILLLFYVMFLMMA
                     VSLNRNAKLQQENLFLSLQQERYENLCMAIEEARQARHDVRHHFVRLSALAEQGDMEKI
                     KEYLSAATGKISDFNLHFCENQAVDSIFGYYSALAERENIPFHAVVSMPAELSLDEINL
                     CLVFSNLLENAIQASAKTEPARRKINVEVYPHHNHLLLIHVENTFDGKIQQKNNIFQSS
                     KRSGNGIGIESVRHITDKNGGTCDFTYEDGIFSAKIMLRI"
     CDS             complement(10197..10913)
                     /locus_tag="ctg71_9"
                     /transl_table=11
                     /translation="MRIAIVDDISEERTLLRNRLESQFSRHNVHVDIFEYENGEAFLTA
                     AKECPFTVVFLDIYMNGSNGIDTAKELRRSDTDCLLIFTTTSTDHALEGFQVRALHYLV
                     KPYSENDISALADEILSRIPDSGKYIDVKVNGSNIQIPFRKIIYAEHFSHMIHIYTAGE
                     RELVTRQSFDSFITSLKMDSRFYQCNRGVVINLEHAVDFDGSGFRLDNGSNVPVSRKLI
                     KNARQTFMEFLFQRRS"
ORIGIN
        1 tctttgcgca tttacaggtt ttcatataat ttatttgaag tagcacaata ggttacatta
       61 caaaagcata attcaggacg atgccgttgc aggaaagcat aacagcaact gcctgatgtc
      121 cataatcctg ttttttcttt aaatgagact ggtgaaagta cgcatcttca attggatgta
      181 atgcccgtga caaaggctta gtctttgaag ctatcgtatc atccacaatg cagaaaacag
      241 gatttccggt acgtgcagct tctgaataaa taatctcaat gacagcctgt tttaatgtat
      301 ctgaaagtaa tgaatcattt catttcccgg aattaaggaa atgagcgatc gtagttctgt
      361 ggcaggagct gtttttagca aaatccgtgg tttttccatg gtatcctgag ataaaaatgc
      421 tgatcaggat actcataaga tgatttatga cccggttcga atagaattgt tactattcac
      481 aggtagtatc ccgcgaggcg ttttgccatg aatatggcaa aatcccgaga catacagggc
      541 aaaatgccat caccgaaggt gatttggaat gcattttgac caagttactg tgaacggagt
      601 gaacagtaac atatatgtaa aacacagcga agtgttaaaa taagaaatta ttgacagtgt
      661 tttttttaca tgttatgata aagtcgattt tgagagacga agatgcagag taacagacag
      721 agtcttttca aagcaattgt tttggatcac ccatcagggt taaggccata cggacagccg
      781 ggtccactgc cgattatggt aactttggtt gccttattga ttgagttaga agctcaaatt
      841 ttataagtag gttcctttga taaccgagat gcgcccaaag cgcagacttg tgaaacgatc
      901 aataagagta gtaaaagtat gattgctata tagactctga cacgcatgcg aatacagatc
      961 agacgcaggt ttgtggctta gtgccctaat ctgcgttttt ttattttgct cagtttgtgg
     1021 aatgtggttt gagggttgag acaaaggaaa ctggaaatgg aggaatgatg aaaggaagtc
     1081 gttttaaatt gaaccagaat catgcaccga tacatgaagc tctggagact ttccgacgaa
     1141 tgcgagttgt accctttgat gttcccggtc ataagcgggg aagaggcaat ccggaactga
     1201 cagaatttct gggacaaaaa tgtgtagggg tggatgtcaa cagcatgaaa ccgctggata
     1261 atctctgtca tcctgtatct gtaatccggg aagcagaaga actggcagca gatgcatttg
     1321 gagcagcaca tgcttttctg atggtgggag gcacgaccag ttccgttcag accatggtcc
     1381 tgactgcctg caaacgcgga gatgagatca tactgccccg taacgttcac aggagtgttt
     1441 tgaatgcact tgtcttgtgt ggcgcgattc ctgtttatgt aaacccagag gtggatcaga
     1501 gacttggaat ttcacttgga atgcgcaggg agcaggtaga aaaagcaata aaggaacatc
     1561 cgaaggcagt tgcggttctg gtaaataatc cgacgtatta tggaatatgc agtgatctgc
     1621 gtgcgattgt caagatggca catgatgcag gaatgctgtg tctggcggat gaggctcatg
     1681 gaacgcattt ttactttggc ggaggtcttc cggtttcggc tatggcagca ggtgcagata
     1741 tggcatcggt atctatgcat aagagtggtg gaagtcttac acagtcgagt cttcttctta
     1801 caggtccgaa cgtccacgca ggatacgtgc gccagatcat taatctgaca cagacgacct
     1861 ctggaagtta tcttctgatg tcaagtcttg acatttcaag aagaaatctt gcacagcgtg
     1921 gccgtcagat ttttcaccag gtagcagata tggcagaata tgccagagag gaaatcaatg
     1981 cgatcggtgg ttattatgca tttggaaaag aactggtaaa tggaaattct gtttttgact
     2041 ttgatattac gaaattaagt gtacatacac tggatattgg acttgcagga atcgaagttt
     2101 atgatattct gcgggatgaa tatgatattc agatagaatt tggtgacatt ggaaacattc
     2161 ttgcgtatct ttccatcgga gaccgtgcac aggaaataga acgactggta agtgcgcttg
     2221 cggaaatccg cagacgtttt cagacagatg gatcaggact tctcagtcag gagtatattg
     2281 atccacaggt agtgacaagt ccacaggaag ctttttatgc agataaatgc agtctgccgc
     2341 ttcgagaaac ggagggaaag gtctgcagtg aatttgtgat gtgttatccg ccgggaattc
     2401 cgattcttgc acccggagaa cggatcacag cagagattct ggattatatt gaatatgcaa
     2461 aagcaaaggg ttgcaatatg acaggccccg aagatccgga tattttgaga ttaaatgtac
     2521 tggcagggag ggaatgacaa tggaaatgtg gttttcggaa tttcatacac cggatgtcaa
     2581 gcacagtatc cgggtaaatc gtcagctcta ttcgaagcag agcgactatc agagaattga
     2641 tgtctttgag acaccagaat ttggacgtgt gctgactctg gatggaaatg taatgctgac
     2701 agagcgtgat gaatttatct atgatgagat gatcacgcac gtgccgatgg caatacataa
     2761 ggaagcaagg gatattcttg tgattggtgc cggagatggc ggcgttgtcc gtgaactgac
     2821 cagatatgac agagtacggc atattgatct ggtagaaatg gatccgatgg ttgtggaagc
     2881 ctgtcgtgcc tatcttccgg gaaatgcctg cagactggat gacagaagag tacatcttca
     2941 ttatgaaaat gcgctgagat ttatccgtcg gtgtgaagca aaatatgacc tcatcattgt
     3001 ggattcttct gatccgtttg gcccttctga aggtttgttt acccgtgaat tctatggaaa
     3061 ctgttacaac gcactgaagg atgacgggat tatggtaaac cagcagggaa gcccgttcta
     3121 tgcggaagat gcacatgcca tgcagcgcag tcataagaga attgccagca cttttcagat
     3181 cagccgtgtt tatcaggcgc acataccgac ttttgctgcg ggttactggc tgtttggatt
     3241 tgccagtaaa aaatatcatc cggtggatga tctggatgca gaggcctgga atgcattaaa
     3301 tcttcgcacg cgttactata cgacaagact ccataaagga gcattttatc ttccggcatt
     3361 tctggaagat atgctgaaag aagtggagga ataatttatg atcttaccta atatagaaac
     3421 tttcattgga tgcgaaagta gttttgagga ggcatctatt gttctttacg gtgcaccctt
     3481 tgattctaca acaagttttc gtccgggggc ccgttttggt ccggcagcca tgcgacatga
     3541 gagctttggt ctggagacct acagtccata tcaggacaga gatcttatgg acatcagagt
     3601 atttgacagc ggagatctgg aactttgttt tggaagcagt gaaatggcac tttcagatat
     3661 tgaaaagaga gcagaagaga tattaaacgc aggaaaattt cccctgcttc tgggaggcga
     3721 acatctggta acactggcag ctgtgcgtgc cgcagcagct aaatatccga accttcatat
     3781 cattcatttt gacgcacatg cagacttaag agatgattat ctgggagcaa aattaagtca
     3841 tgcctgtgtg cttcgaagat gccatgaaat tctgggagat gatcacattc atcagttctg
     3901 catccgaagc ggtgagagag aagaatttca gtttgccaga aagcatacag attttcatcc
     3961 gtttacgttt gagggattga aggaaacggt cagggaactg aaagagaaac aggttccggt
     4021 atattttaca attgatctgg attgtctgga tccgtcagta tttccaggaa caggaactcc
     4081 ggaggcaggc ggcgtgagct ttatggaact tcttgaagcc atccgcatgg tttctcaggc
     4141 gaatgtggta ggagcagatg ttaatgaact ggctcctatg ctggatgcga gtggtgtttc
     4201 aactgcaacg gcctgcaagg ttcttcgaga actgcttctg gcaattgcaa aataaaatga
     4261 taccagggtc atccccgaca ccataaaaat aatattataa aataagactg ttgaagaaac
     4321 agccagttat cataaaagga gaaaaattat gagcagagta cttgtaatcg gctgcggagg
     4381 agtagccagt gtagcaattc agaaatgttg ccaggttgac gaggtattta cagaaatgtg
     4441 tattgcaagc cgcacaaagg aaaaatgtga tgcactcgtg gaaaaactga aaggaaagac
     4501 aaaaacagtt cttactacag ctaaggtgga cgcagatgac gtagaccagt tgatcgagct
     4561 gatcaacagc tataaaccgg atctggtaat gaacatcgca cttccatatc aggatctgac
     4621 aatcatggat gcatgtctgg catgtggtgt aaattacatg gatacagcaa actatgagcc
     4681 ggaagatacc gatgatccgg agtggcgtgc aatctatgaa aaacgctgca aagaagaagg
     4741 attttccgca tattttgact attcctggca gtgggcatac cgtaaaaaat tcgaagatgc
     4801 aggacttaca gcacttctcg gatgtggatt tgacccgggt gttacacagg cttactgtgc
     4861 ctatgcatta aagcatgaat ttgatcagat tgatacgatt gatatcctgg actgcaatgg
     4921 cggcgatcat ggatatgcat ttgcgacaaa ctttaacccg gaaatcaatc ttcgtgaagt
     4981 aagtgcaccg ggaagctact gggaaaacgg acactgggtg gaaatcccgc cgatggatat
     5041 caagagagaa tataactttg atcaggtggg agataaggat atgtacctgc ttcaccatga
     5101 ggaaattgag tctcttgcaa aaacaattcc gggtgtaaaa cgtattcgtt tctttatgac
     5161 tttcggacag agctatctgg atcatatgcg ttgtcttgaa gatgtaggaa tgctttccac
     5221 aacaccgatc cagtacaatg gacaggagat tgttccaatt cagttcctga aagcactgct
     5281 tccggatccg gcaagccttg gaccacgtac aaaaggaaaa acaaatatcg gctgtatctt
     5341 tacaggtgta aaagacggaa aagaaaagac atactatatc tataatgtat gcgatcatca
     5401 ggaatgctat cacgaagttg gaagtcaggc gatcagctat acaaccggtg ttccggcaat
     5461 gtgcggagcg cttatgatgc tgaccggaaa gtggatcaga ccaggtgtgt atacagttga
     5521 agaatttgat ccggatccgt tcctggatgc actcgaccgt tatggcctgc cgcgcagtga
     5581 aagccacgat ccgaagctgg tagactgatg gaaggattgg ataaaagagc accatttaca
     5641 gccaccggcg gaatgattcc gccggaattc aggaatataa aaacaccctg ctatatcctg
     5701 gacgaaaaag cacttataaa aaatgcaaaa ctgctcggtg aagtggcaga gcggacagga
     5761 tgtaagatgc tcctggcgca gaaagcgttc agcaattatg actgttatca gttttttgag
     5821 ccgtatcttg cgggtacaga ggccagtgga ctatttgagg cacgactcgg ggcagaggag
     5881 atgccgggaa aagaggttca tgtattttgt gccggttatc gggcagatga atttgaggat
     5941 cttcttcagt acgcggatca tatcgtgttt aattctccgt cacagcttct tcgtttcgga
     6001 caaagagcaa aagaagcgag aaagagtgtg ggacttcgga ttaatccgga atgttccact
     6061 caggaaggac atgagattta tgatccctgt gcgccgggaa gccgtatggg aacaacaaga
     6121 gcacagtggg atgaagcatt ccagaaaaat ccggagcttt tggatttact ggatggtctt
     6181 catttccata ccctctgtga gcaggattcc gacgatctgg agaccactct tatttctgta
     6241 aagaagcatt ttggagatct ggcttccaga gtaaagtggg ttaattttgg tggtggtcat
     6301 catattacaa gaccaggcta tgatattgaa cgactggaac gatgtatccg gatggtacaa
     6361 gaggaatgga aggtagatgt ttatcttgaa cccggagaag catgggcatt aaatgcagga
     6421 ttccttctga cccgtgtgct ggatgttctg aaaaacggag agacagaaat tgcgatcgta
     6481 gatgccagtg cggcctgcca tatgccggat gtactggaaa tgccgtatct tccgccgctt
     6541 cttggggcag atgatataga agagagagga accacagttc gccttggagg gccaacctgc
     6601 ctgtcgggag atgtgatcgg agactataaa ttcagacagt ttccggaata tggggatctt
     6661 cttatgtttg gagatatggc catctatact acctgtaaaa ataatacatt taacgggatg
     6721 ccgttaccgg atatctggct cagacgtgct gacagtacta tgcagcagct tacggatttt
     6781 ggatacgggg attttaaggg aagacttgga agtcgcaaat agcgacttcc ttttttggtg
     6841 gaatgcatgt atatagttca ttacaaatct cataaagtat tataagagca gagtagaaaa
     6901 tcttccgttt tataggcaga gaggacgcag atggttacaa tcagtctttg catgatcgta
     6961 aaaaatgagg agagagtgct tggcagatgt ctggaatctg tgcaggagat tgcagatgag
     7021 attatcatag ttgatacggg gtctgaagac cggacaaaaa agattgcaga aaaataccat
     7081 gccagagtat ttgaacagga atggcaggat gatttttcaa gagcgaggaa ctattctttt
     7141 tctcaggcag agatggacta ctgtatgtgg cttgatgcag atgatattat tacgaaaagt
     7201 gaagtgctga aactgaagcg atggaaagaa gaaacagacg gatcatcgga tgtggtaatg
     7261 atccgatatg tggcaggctt tgatgaaaaa agaaatccga cattagtcta ttatcgtgaa
     7321 agaatagtaa aaagagataa ggactttcag tggcagggac gggtgcatga gacgttagcc
     7381 gtcagaggca ggacggaata cctggactgt gagatagaac atcacagcat aaaaacggaa
     7441 tactcaagaa gaaatctcga gatatatcaa aagatggaat cagatggaga agtattatcg
     7501 gcaagagaca gattttatta tggacgagag ttgttttatc acagggagta tgtggaggcg
     7561 gtggataacc tcctgaaatt tctgcaatta ccggagggat ttgtggaaaa ccaggtggag
     7621 gcatgcagag tggcagcacg atgctgttat gaactgaaac aaaatggaat ggcactggag
     7681 tttctgtaca ggggactgac ataccggaca ccgtcgggag aactatgctg tgatataggc
     7741 aaacatttct ttgacagaaa gaaatgggaa caggcagtat tctggtacag aaatgcactg
     7801 caggtatctg agaatgcaaa gacaggaggt tttgtggaaa aagagtgcta tggctatatt
     7861 ccatgcattc agctgagtgt ctgctggtat tatcttggcg atattgaaaa agcgtttcag
     7921 tatcattgtc aggcgggcac gtataaacct tacgggagag aatttctgaa aaatcagcag
     7981 tattttatct cagtcaaaca gtaaatacag atcaccgatg tacatctgac tattgttgtc
     8041 tgaagtaaag ggaacaggaa agactgactg tgcatatcct aaagagagaa atattttagc
     8101 agggatcaat atatggagtt tttcagaaaa aacagagaag ctgactgtta gagtcagggc
     8161 tgctgcaact gtggatgtcc gggtccgacc ggtcccatgg gaccaagagg atgccccgga
     8221 gcaacaggac cgcagggtcc tcagggatta cagggagtct agggaccaac gggtgcagct
     8281 gggccgacag gagcaactgg agccaccgga ttgcagggac cacagggaat tcagggtccg
     8341 gccggagccc agggagcaac agggccgcag ggaatccagg gaccaattgg tgtgacggga
     8401 gcaacaggcc cagccgggcc acaggggagt ccaggtgcaa ccggtccggt tggtgcagat
     8461 ggaccagtag gagcaaccgg tccaaccggc cccacaggcc ccgcaggtac cataactcct
     8521 gcagcagcgg tcgcaaatgc gacaagtgcg gaagatgtgg taaatcagtt taatcttctg
     8581 cttgcaaata tgcggacagc aggattgctg gcagaatagg acagagtaaa gtaactgtcc
     8641 acaataacta aaaaacatgg tatgacaggg catctctgtt gtactgtgtt tttttcttta
     8701 taaaaagata tataaaaacg gaatatgtct ggtataaaaa ggaatatatc aatatccccc
     8761 gacggggctt attgcaataa aatgaaataa aagcagaaat cagacttgca ggaggtaata
     8821 atgtcattgt attttttatt gatacgtgga tgctccggat ataatcagta actgattata
     8881 tccggagcat tattttagcg gagaaaatac catcttcata ggtaaagtca caggtaccgc
     8941 catttttgtc ggtaatgtgg cggacggatt cgattcctat gccgtttccg gagcgtttgg
     9001 aggattggaa aatattgttt ttttgctgta ttttgccatc gaaggtgttc tccacatgaa
     9061 tcagaaggag atgattatgg tgggggtaaa cttccacatt aatctttctg cgggcaggct
     9121 ctgttttcgc acttgcctgg atggcatttt ccagcagatt ggaaaacaca aggcacagat
     9181 taatctcatc taaggaaagc tcagcaggca tggaaaccac tgcatgaaaa ggaatgtttt
     9241 ctctttctgc aagggcggaa taatatccga aaatactgtc aacagcctga ttttcacaga
     9301 aatgcaggtt aaagtcagag atttttccgg ttgcagcgga gagatattct ttaatttttt
     9361 ccatgtcacc ctgttctgcc agagcggaca gtcggacaaa atgatggcgg acatcgtgac
     9421 gggcctgtct tgcttcttcg atggccatgc agagattctc gtacctttcc tgctgaagag
     9481 aaagaaaaag gttctcctgc tgaagtttgg catttctgtt caggctgact gccatcataa
     9541 gaaacatgac ataaaacaga agcaggatta tgagcagtac aagacttaaa acaatataac
     9601 actgcaggac ccgcccggta tataaagtac tgcggtattt aggaatcata aaaagattca
     9661 ttcctatgaa gatcaccgga agaatccaga atacatacca ggtctgggca aagttctcgt
     9721 ctgcgatcat tgtctgtaca tagtggcagg caggatacca gactgccaga acaaacagca
     9781 gacagatgac gttataaaaa attccggcac cagtgtgcaa ccacagttcg ttttctgcaa
     9841 tatgcaggtc agcagtcata agggcattga gtgcccggga cagacttttg atacatgtaa
     9901 aaactgcgaa gactgccaga aaaatactga cggatttcca gacagagatt tttaatgttt
     9961 tatggtaaat gagcataatg acaggcagca gaggaaacag gaaccatctg gtgggaattt
    10021 gcagggcaca gcaaactgcc cctcccaaaa tacagattcc cagaagaagg ggaagaagcc
    10081 atgctgtcag cttaagcggt gtctgcctca gatagctttt tacaggcaga tatgccagca
    10141 gtataccggg aatgattacg gaaagttcaa gtacagggca aagtatgtca gtcatttcag
    10201 gacctcctct ggaacagaaa ttccataaat gtctgtctgg cgtttttaat aagcttcctg
    10261 ctgaccggga cattgcttcc gttatcaagg cgaaagcctg atccgtcaaa atcaacggca
    10321 tgctccagat tgatcacaac gccccggtta cattgataga aacgtgagtc cattttcagg
    10381 gaggttatga aggagtcaaa ggactgtcgg gtgaccaatt ccctttcacc ggcagtgtag
    10441 atgtggatca tgtgggaaaa atgctctgcg tagattattt tccggaaggg aatctgaata
    10501 ttactgccgt ttacctttac atctatgtat ttcccggaat ccgggatgcg ggaaaggatt
    10561 tcatctgcca gtgcggaaat atcattttca ctgtagggct ttacaagata gtgcagagcc
    10621 cggacctgga atccctctaa tgcatggtcg gtagaagttg ttgtaaagat cagcagacag
    10681 tcagtatctg atctgcgaag ttcttttgct gtatcaatcc cgttggatcc attcatataa
    10741 atatccagaa acaccacagt gaacggacat tccttcgctg cagtgaggaa agcttctcca
    10801 ttttcatatt caaatatatc tacgtggaca ttgtgcctgg aaaactgaga ttccagtctg
    10861 ttgcgaagca gtgtccgttc ttctgaaata tcatcaacaa ttgcaattct catagtaaat
    10921 cttcctttat ttatatgttt ataaaattct gctataagta tatcacaaaa caataccata
    10981 gatttacaat tcgtgtcatt ttctgtcgtt tcgtgacaga attatt
//
