LOCUS       c00274_gnlPro..         4356 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DBFMDGLB_274.
ACCESSION   c00274_gnlPro..
VERSION     c00274_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 21:03:01
            Original ID  :: gnl|Prokka|DBFMDGLB_274
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4356
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4356
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[107:4349](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      108..4349
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..4356
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4356
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             108..4349
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg274_1"
                     /sec_met_domain="HGD-D (E-value: 7.4e-65, bitscore: 205.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.2e-38, bitscore:
                     119.2, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYKTLGIDIGSTTVKIAILDENENLIFADYKRHFANIQETLADL
                     LQEAFDQYGEMTLHPVITGSGGLTLANHLGVPFTQEVIAVSTSLQKLAPKTDVAIELGG
                     EDAKIIYFENGNVEQRMNGICAGGTGSFIDQMASLLQTDATGLNEYAKDYKALYPIAAR
                     CGVFAKTDIQPLINDGATKPDLSASIFQAVVNQTISGLACGKPIRGHVAFLGGPLHFLS
                     ELRESFIRTLKLDEEHTIIPENSHLFAAIGSALNAKEDNSISLTEMKDRLRNSIKLDFE
                     VERMEPLFASQEEYDTFAKRQSSYKVKTGDLATYKGNCYLGIDAGSTTTKTALVGEDGT
                     LLYSFYSSNNGNPLKTTIRSIKEIYELLPEDAKIAYSCSTGYGEALIKAALILDEGEVE
                     TVSHYYAAAFFDPEVDCILDIGGQDMKCIKIRNKTVDSVQLNEACSSGCGSFIETFAKS
                     LNYTVQDFAKAAVFAQHPIDLGTRCTVFMNSKVKQAQKEGAEVSDISAGLAYSVIKNAL
                     YKVIKVSDASELGRHIVVQGGTFYNDAVLRSFEKIAGCEAIRPDIAGIMGAFGAALIAR
                     ERHQEGAETTMLSIDKINELKYTTSMANCRGCTNNCRLTINKFSGGRQYVSGNRCERGI
                     GKEKNKDHIPNLYEYKYKRIFSYTPLTADKATRGKVGIPRVLNMFENYPFWYTFFTELK
                     YEVVLSPTSTRKIYELGIESIPSESECYPAKLAHGHVTWLIRNGVKFIFYPCIPYERNE
                     FPDAVNHYNCPIVTSYAENIKNNVDELNDPSITFRNPFLAFTSEEILANRLIEEFKDIP
                     AEEIKAAVHKGWEEMAAARRDVQKKGEETLKYLEETGRHGIVLAGRPYHIDPEIHHGIP
                     DLINSYGIAVLTEDSISHLAPVERPIRVNDQWMYHSRLYAAANYVKTRDDLDLIQLNSF
                     GCGLDAVTTDEVYEILDGSDKIYTCLKIDEVNNLGAARIRIRSLIAAIRAKKAQGQKRT
                     VKPASIDKVSFTKEMRKDYTILCPQMSPFHFSLLQAAFNSCGYNLEVLPNDNKHAVDVG
                     LKYVNNDACYPSLIVVGQIMDALLSGKYDLNKTAVVMSQTGGGCRASNYIAFIRRALKK
                     AGMEQIPVISVNLSGLESNPGFKLTLPLVKKIAYGAVFGDILMKCVYRMRPYELEEGIV
                     NRKHKIWEQRVISFLSGSSVSHSQFKKMCREMVHEFDTIPISDVKKPRVGIVGEILVKF
                     LPAANNHLAELLESEGAEAVVPDLIDFMCYCFYNQNFKVENLGFKKSKATMANWGIKAI
                     EWVRKPASEALAQSRHFAPPADIRDLAKMASPIVSTGNQTGEGWFLTGEMMELIHGDVP
                     NIVCIQPFGCLPNHIVGKGVIKEIRREYPTANIVAIDYDPGASEVNQLNRIKLMLSTAQ
                     KNLKKAEEKNA"
ORIGIN
        1 cggcaatgga attttggctt gtatgtctcg ggatagtggt gtgtgaacag taacaggaaa
       61 atttcatttt tgtttatata caatacgagg aggcttgaat ttactttatg aattacaaaa
      121 cacttggaat tgacattggt tccactactg taaagatcgc gatcttagat gagaatgaaa
      181 atctcatttt cgcggattac aagcgtcatt ttgcgaacat tcaggaaacc cttgcagacc
      241 ttcttcagga ggcctttgac cagtatggcg agatgactct ccatcctgtg atcacaggtt
      301 ccggcggtct gacccttgcc aaccatctgg gcgttccttt tacccaggag gttattgcag
      361 tttctacttc tctgcagaag ctggcaccaa agacagatgt tgccatcgag cttggcggtg
      421 aggatgccaa gatcatttat ttcgaaaacg gaaacgtaga acagcgtatg aacggtatct
      481 gtgcaggcgg taccggttct ttcatcgacc agatggcttc tcttctccag acagatgcca
      541 caggtctgaa tgaatatgcc aaagattaca aagcgctcta cccgattgct gcccgctgcg
      601 gtgttttcgc caaaacggat atccagccgc tgatcaatga cggtgcaacc aaaccggatc
      661 tgtcagcttc tattttccag gcagttgtaa accagactat ttccggtctt gcctgcggaa
      721 aacccattcg tggacatgtt gcattccttg gtggtccgct tcacttcctg tccgaattga
      781 gagaatcctt tatccgtact ttgaagctgg atgaggaaca cactatcatt ccggagaact
      841 cccatctttt tgcagccatt ggttctgcat taaatgcaaa agaagacaac tccatttccc
      901 tgacagaaat gaaagacaga ctccgcaatt ccattaagct ggattttgaa gtagaacgta
      961 tggaaccact tttcgcttct caggaagaat acgatacatt tgcgaaacgt cagagttcct
     1021 acaaagtaaa aacaggagat ctggctacat ataaaggaaa ctgctatctg ggtattgatg
     1081 caggttccac cacaaccaaa actgcactgg taggtgaaga cggaacactt ctctactctt
     1141 tctacagcag caacaacgga aacccgttaa aaactaccat ccgttctatt aaagaaatct
     1201 atgagctgct tcccgaggat gcaaagattg cttattcctg ttctacaggt tacggcgagg
     1261 ctctgattaa ggctgctctg atcctggatg agggcgaggt tgagaccgta tcccattact
     1321 atgcagcagc gttttttgac ccggaggtag actgtatcct ggatatcggc ggacaggata
     1381 tgaaatgtat caagatccgc aacaagaccg ttgacagcgt acagttaaat gaagcatgct
     1441 cctccggatg cggttccttc attgaaacct ttgccaaatc cctgaattat acagtacagg
     1501 atttcgcaaa agctgctgtt tttgcacagc atcctattga tcttggtacc agatgtactg
     1561 ttttcatgaa ttccaaggta aagcaggcac agaaagaggg agctgaggtt tccgatattt
     1621 ccgcaggtct tgcttactct gttatcaaaa atgcactgta taaggtaatc aaagtttctg
     1681 acgcttccga acttggcaga cacatcgttg tacagggtgg tactttctac aatgatgcag
     1741 ttctgagaag tttcgaaaag attgccggct gcgaagctat ccgtccagat attgccggaa
     1801 tcatgggtgc tttcggtgct gcactgattg cccgcgagcg ccatcaggaa ggtgcagaaa
     1861 cgactatgct ctccattgac aagatcaacg aactgaaata tacaacttct atggcaaact
     1921 gtcgtggatg taccaataac tgccgtctga ctatcaacaa attctccgga ggccgtcagt
     1981 atgtaagcgg taaccgctgc gagcgtggta ttggcaagga aaagaacaaa gatcatattc
     2041 cgaatcttta tgaatataaa tataaacgta ttttctccta cacaccgctt actgctgata
     2101 aggcaacgcg aggcaaagta ggtatccccc gtgttctgaa tatgtttgag aattatcctt
     2161 tctggtatac tttctttaca gaactaaagt atgaggttgt actctcccct acttccacca
     2221 gaaagattta tgagttaggt attgagtcca tcccaagtga gtccgaatgc tatcctgcca
     2281 agcttgccca tggccatgta acctggctga tccgcaatgg cgtgaaattt attttctacc
     2341 catgtatccc atatgaacgt aacgagttcc cggatgcagt caatcactac aactgcccga
     2401 tcgttacctc atatgccgaa aatatcaaga ataacgtaga cgaattaaac gatccgtcca
     2461 ttaccttccg caatccgttc cttgcattta cttctgagga aattctggca aatcgtctga
     2521 tagaggaatt taaggatatc ccggctgagg aaatcaaagc tgctgtgcat aagggctggg
     2581 aggaaatggc tgctgcacgc cgtgatgtgc agaaaaaggg agaagaaacc ctgaaatacc
     2641 tggaagaaac aggccgccac ggtattgtcc ttgcaggccg cccataccac attgacccag
     2701 aaattcatca tggtatccct gacctgatca acagctatgg tattgccgta cttaccgagg
     2761 attccatctc tcatctggca cctgtggaac gcccgatccg cgtcaatgat cagtggatgt
     2821 accactccag actgtatgct gctgcaaact atgtaaagac acgtgatgat ctggatctga
     2881 tccagctgaa ctctttcgga tgtggtctgg atgcagttac tacagacgag gtttatgaaa
     2941 tccttgacgg aagcgacaaa atctatacct gcttaaagat tgatgaagta aacaacctcg
     3001 gtgcagcaag gatccgtatc cgctccctga tcgctgcgat ccgtgcaaag aaagctcagg
     3061 gacagaaacg tactgtcaaa ccggcttcta ttgataaagt atcctttaca aaggaaatga
     3121 gaaaggacta taccatcctc tgcccgcaga tgtccccctt ccatttcagt ctcctgcagg
     3181 cagcattcaa ttcctgcgga tacaacctgg aggtgcttcc gaatgacaat aagcatgcag
     3241 tggatgttgg tctgaagtat gtaaacaatg acgcctgcta tccgtctctg atcgttgtgg
     3301 gacagatcat ggatgcgctg ctttccggta aatatgacct gaacaaaacg gccgttgtca
     3361 tgtcacagac aggtggcgga tgtcgtgctt ccaactatat cgcatttata cgacgcgcat
     3421 taaagaaagc cggtatggaa cagattccgg ttatctctgt taacttaagc ggtctggaaa
     3481 gcaatcccgg attcaaactt acccttccat tagtgaagaa aattgcttac ggtgccgtat
     3541 tcggagatat cctgatgaaa tgcgtatatc gtatgcgtcc ttatgaactg gaagagggaa
     3601 tcgtaaacag gaaacataaa atctgggaac agcgtgtgat ctctttctta agcggaagca
     3661 gtgtcagcca cagccagttt aagaaaatgt gccgcgaaat ggttcacgaa tttgatacca
     3721 tccccatcag cgatgtgaag aaacctcgtg tgggcatcgt aggtgagatc cttgtcaagt
     3781 tcctgcctgc tgcaaataat catctggcag agcttctgga atctgaaggc gctgaggcag
     3841 ttgtaccgga tctgatcgat ttcatgtgct actgcttcta taatcagaac tttaaggtag
     3901 aaaatcttgg attcaagaag tccaaggcaa ccatggcaaa ctggggaatc aaagcaatcg
     3961 aatgggtgag aaagcctgca agcgaagctc ttgcacagag ccgccatttt gcaccgcctg
     4021 ctgatatcag agatctggca aaaatggcat ctccgatcgt ttccaccgga aaccagacag
     4081 gtgagggatg gttcctgaca ggtgagatga tggaactgat ccatggagat gttccgaata
     4141 ttgtttgtat ccagcctttc ggatgtctgc caaaccacat tgtaggtaag ggtgttatca
     4201 aagagatccg cagagaatat ccgacagcca atattgtagc catcgactat gatccgggtg
     4261 caagtgaagt taaccagctc aaccgaatca aactgatgct ctccacagct cagaaaaacc
     4321 tgaaaaaagc agaagaaaaa aatgcataaa taatac
//
