LOCUS       c00108_gnlPro..         6908 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IDPHCLGL_108.
ACCESSION   c00108_gnlPro..
VERSION     c00108_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-08 00:01:19
            Original ID  :: gnl|Prokka|IDPHCLGL_108
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6908
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6908
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1572:4821]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1573..4821
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..6908
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6908
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             113..1570
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg108_1"
                     /sec_met_domain="OKR_DC_1_C (E-value: 1.8e-14, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 3.9e-127,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEHLQVLKGGI"
     CDS             1573..2433
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_2"
                     /sec_met_domain="Spermine_synth (E-value: 2.2e-54,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 3.2e-16,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             2430..3710
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_3"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 2.7e-44, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 2.3e-36,
                     bitscore: 113.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKIDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             3700..4821
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_4"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.9e-15,
                     bitscore: 45.9, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDHICDHIIFNS
                     TAQLKKFKDVCTRASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENGIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             4769..5959
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg108_5"
                     /sec_met_domain="PAD_porph (E-value: 5.2e-129, bitscore:
                     418.9, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRLSDISDTKTLRAGFPDICRAIKEKETDMEVTEKNRTKYRMPGE
                     FEPHEGCVMIWPERPGSWNYGAREAQKAFVKVAEAIGESEKVYMLVSKAQMENAKNQLG
                     NVSGVTLLECETDDAWARDVGATMVLDEKGAVCGVDWQFNAWGGDFDGLYRNWEKDDRV
                     AAFICRTLGCPCLDARPFVLEGGSIHSDGEGTLIVTEACLLSQGRNPQMSREQIEEQLK
                     YWLGVHKIIWLPCGIYQDETNEHVDNVCAFVRPGEVVLAWTEDETDPQYAMSLADLKVL
                     EQETDAKGRKFKIHKLPIPQKPVCLTQEDVDGFVFEEGEDEREAGERMAASYVNFYISN
                     GGIILPQFGDENDKRAVEILQKCFPERRIYPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             5901..6104
                     /locus_tag="ctg108_6"
                     /transl_table=11
                     /translation="LLAVEIFTVSPSRFPEKISDPDAENFESHVFEGYYLKVMKKLTYV
                     NRSRRNRQDEKCNSGSSSDEMQ"
     CDS             6061..6906
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg108_7"
                     /sec_met_domain="CN_hydrolase (E-value: 1.7e-56, bitscore:
                     180.3, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTVEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGIYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     R"
ORIGIN
        1 aatatataga gaaataattg aatcattgtg ccggtttgag gcagtataca attgctgaat
       61 gatagaactg tatttgccgg tacatgacga caggaaaaga ggaacatgtc aaatggatta
      121 tgaaagacaa cagcatgcgc ccatatatga agcactggaa cgtttccgaa agaagagagt
      181 cgttcccttt gatgtgccgg gacataaaag aggaagagga aatccggagc ttgcacagtt
      241 gctgggagag aaatgtgtgg ggctggatgt taattctatg aagccgctgg acaatctctg
      301 ccacccggtt tcggtgatca gagaagcgga ggagcttgca gcagatgctt ttggcgcagc
      361 gcatgcattc cttatggtag gaggaaccac atctgcagtg cagagcatga tcctgtctgt
      421 ctgcaaggca ggggataaga tcattctgcc gcgaaatgta cataaaagtg ccatcaatgc
      481 cctggtactg tgcggtgcaa ttccggttta tgtaaacccg gaggtgaatg cgcagctggg
      541 catttccctt ggcatggaag tcagtcaggt ggagaaggct atggatgaga atccggatgc
      601 ggtggcagtt cttgtaaata accctaccta ttatggaatc tgttcggatc tgcggactat
      661 cgtaaagaag gctcatgcaa gaggaatgaa ggtgctggca gatgaggctc atggaaccca
      721 tctttatttc ggcagaaacc ttcctgtatc cggaatggcg gcaggtgctg acatggcggc
      781 agtttccatg cacaaatccg gcggaagtct gacacagagt tcgctgctgc ttttgaataa
      841 gagtatgaat gcagagaaag tgcgccagat catcaatctg actcagacca caagcgcttc
      901 ttatcttctg ttgtccagtc tggatatctc cagaagaaat ctggcactca ggggagagga
      961 atcctttgaa aaggttgcag ggatggcgca gtatgccaga gaggagatca atgagatcgg
     1021 cggttattat gcatatggta tggatctgat caacggaacc agtgtttttg attttgatgt
     1081 tacaaaactc tccatttata cactgggaaa tgggttggca ggtattgaag tttatgatct
     1141 tctcagagat gaatatgata ttcagatcga gtttggagat atctgtaata ttctggctta
     1201 catttccatc ggagacaggc ttcaggatat tgagagactg gtaggggcat tggctgatat
     1261 tgaacgtctg tataagaagg acagtacagg tatgctttcc ggggaatata tcgcacctgc
     1321 agtggtggcg tctccacagc aggcatttta tgcggagaaa gaatctctgc ccatggaaca
     1381 ggcggcaggc aggatcagcg gtgaatttgt tatgtgttat cctccgggaa tcccgattct
     1441 tgctcctgga gaaatggtga cacaggaaat tgtagaatac attctttatg caagagacaa
     1501 aggctgttcc atgcagggaa tggaggatcc gaaggtagaa catcttcagg tcctgaaagg
     1561 gggtatctga ttatggaatt atggtattcc gagttccata caggaaatgt aaagctttct
     1621 gtccggatta accgacagtt attttcaggg gaaagtgaat ttcagagaat cgatgtgttt
     1681 gagtctgaag aatttggaag atttgtggct ctggacggtg agatcgtatt ctctgataaa
     1741 gatgaattta tttatgatga aatggtcacg catgtgccaa tgacagtaca tcccaatgta
     1801 aaaaatgttc tgatcatcgg tggcggtgac ggtggagttg ccagagaact gatccattat
     1861 ccacagattg agagcattga tgtggtggaa tccgataaaa tgtttgtgga tgtatgtgcg
     1921 gagatgtttc cggatattgc ccagggactg aaggatgaga gagtcaacat ttattatgaa
     1981 gacggccttc ggttcctgcg gaataaaaag gccagatatg acctgatcat caatgattcc
     2041 acagatccgc tgggacatac agagggactt tttacaaagg aattctacgg aagctgttat
     2101 aaggctctca gagatgacgg aatcatggtt tatcagcatg gaagtccttt ttatgatgag
     2161 gatgaggtgg aatgcagaaa gatgcacaga aaggttttcc ggtcatttcc ggtgagcagg
     2221 gtttatcagg cacatatccc tacctgtccc tcgggatact ggctttttgg atttgcatca
     2281 aagaaatatc atccactgga agatttcagg ccggagaggt ttgataatct taatatagaa
     2341 acatggtatt atacaacaaa ccttcacaga ggagcattta tgcttccaaa atatgtagaa
     2401 gatttactgg aagaggagga aaacagttta tgagcagatt attggtaatc ggatgtggtg
     2461 gggtagcttc agtggcaatt cgcaaatgct gtcagaacag cgatgttttt acagagatta
     2521 tgatcgcaag caggacaaag gaaaaatgcg atgcactcaa agagaagatt gaaagtacaa
     2581 cgaagacaaa aattgagaca gcaaagatag atgcggataa tgcagcagag gtcgcagaat
     2641 tgatcagagc ctataagccg gatgctgtcc tgaatgtggc acttccatat caggatctta
     2701 ccatcatgga tgcatgtctg gaagccggtg cggattatat tgatactgcc aattatgaag
     2761 cagaggatac agaagatccc acatggcgtg caatctatga aaagagatgt aaagaaaaag
     2821 gctttactgc atatttcgat tattcctggc agtgggctta tgatgagaaa tttaaggaag
     2881 caggactgac tgctcttctg ggaaccggtt ttgatccggg tgttaccagt gtattcagtg
     2941 cttatgccct gaagcattat tttgatgaaa tccataccat tgatattctg gactgtaacg
     3001 gcggtgatca tggatatcct tttgccacaa actttaaccc ggagatcaat cttcgagagg
     3061 tttccgcaaa tggttcctac tgggaagacg gacattgggt agaaacagag cctatggaat
     3121 ttaaatctgt ctacgatttt cctgaggtag gaaagaagga tatgtatctt cttcatcatg
     3181 aagagattga atcactggca aaaaatattc cgggagtaca gagaatccgt ttctttatga
     3241 cattcggaca gagttatctg acacatatga aatgtctgga aaatgtagga atgctttcca
     3301 ccgcacctgt ggaatttaat ggacaggaga tcgtgccgat ccagtttttg aaagctcttc
     3361 tgccggatcc tgcatctctg ggtccgagaa cagtgggtaa aacaaatatc ggctgtattt
     3421 tcacaggtgt taaggacgga aaagagaaaa gtatttatat ttataatgta tgtgatcatc
     3481 aggaatgcta taaagaggtg gaatcccagg caatctccta tacaacaggt gttccggcta
     3541 tgatcggttc catgatggta gtgacaggac agtggaagaa gccgggtgta tttaatgtgg
     3601 aagaatttga tccggatcca tatatggaag cactgaacaa atggggactt ccatggaaag
     3661 tctgcgaaga tcctgaactg gtaaaggtct ggaaagccaa tgaagattga tcaactgcaa
     3721 actccctgct atgtgatcga tgagaagaag atgcgggaga atctggagat tttgaaaaaa
     3781 gtccaggagg ataccgggtg taagatcctt ctggcgcaga aagcgttttc cggctttgcc
     3841 ctgtatccca tgatcggaaa atatctggca ggtaccactg ccagcggtct gtttgaggca
     3901 aggcttggat atgaagagat ggggaaagag aatcatgttt tttcccctgc ttaccgtaca
     3961 gaagatatag aggaactgga tcatatctgt gaccatatta tctttaattc cacagcacag
     4021 ctgaagaaat ttaaagatgt gtgtaccaga gccagtctgg gactccgtat taatccggaa
     4081 tgctccactc agggggatca tgcgatctat gatccctgtg cgccgggttc caggctgggg
     4141 gttaccagag agaactttga cggggaatgt ctgaaatgga tcgacggact gcattttcat
     4201 actctctgcg aacagaatgc ggatgatctg gagaaaacat tgcaggcggt agaggagaag
     4261 tttggagaat ttctgtctga ggtttcctgg ctgaatatgg gcggcggaca tcatattacc
     4321 agagaggatt atgatgtaaa gctcctggaa aaatgtattc agcatatgaa ggaaacctat
     4381 gatctggata tttatctgga gcccggggag gctgttgccc tgaatgccgg atatctggtg
     4441 acagaggtta tggacattgt ggagaatgga atcagaacgc tgattttgga tgcttctgca
     4501 gcctgccata tgccggatgt gctggagatg ccatatcgtc cgcctcttaa ggacagcggg
     4561 gaagcagggg agaaggcata tacctaccgc ttatcttcct gcacctgcct ggcaggagat
     4621 gtgatcggag attattcctt tgacagagag atccggatcg gggacaagct gtattttatg
     4681 gatatggcga tttattctat ggtgaagaat aatacattta acggtatgcc gctgccggat
     4741 attgcggtta tgcatgagga cggagagtgt gaggttatca gacatttcgg atacgaagac
     4801 tttaagagcc ggctttcctg atatctgccg ggctatcaaa gaaaaggaga cagacatgga
     4861 agttacagag aagaacagaa caaaatatcg tatgcccgga gaatttgagc ctcatgaggg
     4921 atgtgtgatg atctggccgg aacgtcccgg ttcctggaat tatggggcaa gggaagcaca
     4981 gaaagcattt gtgaaagttg cagaggctat tggagagagc gaaaaggtgt atatgctggt
     5041 ttccaaagct cagatggaga atgcaaagaa tcagcttggg aatgtttccg gtgtgacttt
     5101 gctggaatgc gagacagatg atgcctgggc gagagatgtg ggagcaacca tggttctgga
     5161 tgagaaaggg gcggtctgtg gagttgactg gcagtttaat gcctggggag gagactttga
     5221 cggactttac cggaactggg aaaaggatga cagggtggct gcctttatct gcaggactct
     5281 cggttgtcca tgtctggatg ccagaccttt tgtgctggag ggcggttcca tccattctga
     5341 cggagagggg actctgattg ttacagaggc ctgtcttctg agtcagggac gtaatcctca
     5401 gatgagcagg gaacagatag aggaacagtt gaagtactgg ctcggtgtcc acaagattat
     5461 ctggcttcca tgtggaatct atcaggatga aaccaatgag catgtggata acgtgtgcgc
     5521 ttttgtaagg cccggagagg ttgtgcttgc atggacagag gatgagacag atccgcagta
     5581 tgccatgtct ctggctgatc tgaaggtgct ggaacaggaa acagatgcaa aaggcagaaa
     5641 atttaagatt cataagcttc cgattcctca gaaaccggtc tgccttaccc aggaagatgt
     5701 ggatggcttt gtgtttgaag agggagaaga cgaacgggaa gcaggagaac ggatggctgc
     5761 cagttacgtg aatttctata tttccaatgg agggatcatc cttccacaat ttggggatga
     5821 aaatgacaaa agggcagtgg agattctgca gaagtgtttt cctgaaagaa ggatttatcc
     5881 cattgatgcc agagccatca ttgttggcgg tggaaatatt cactgtatca cccagcagat
     5941 tcccggaaaa aatatctgac cctgatgcag aaaactttga gagtcatgtg tttgagggtt
     6001 attacctgaa agttatgaaa aaacttactt atgtaaacag gagcaggagg aacagacagg
     6061 atgagaaatg taacagtggc agcagttcag atgaaatgca gtaaaagtgt ggagaaaaat
     6121 attgcccatg cagaggaact ggtgcgtcag gcagcagcaa agggagctga gattgttctt
     6181 cttccggagc tttttgaacg gccctatttc tgccaggagc gcagatatga gtattatgaa
     6241 tatgcgcaga ctgtagagga aaaccctgca gtgcgtcatt tcagcagggt agcggcagag
     6301 ctggggattg tgatcccggt cagcttttat gaaaaagagg tcaataatac ttataacagc
     6361 gttgcggttc tggatgcaga tgggaagaat ctcggcattt atcgaaaaac acatattccg
     6421 gatgatcatt attatcagga aaaattctat ttcacaccgg gagacaccgg ctttaaggtt
     6481 tttgatacca gatttggaac catcggagtt ggaatctgct gggatcagtg gttcccggaa
     6541 acagcaagat gtatggcgtt gcagggagca gagcttctct tttatcccac tgccatcgga
     6601 agtgagccca tcctggaatg tgacagcatg gaacactgga gaagatgtat gcagggacac
     6661 gctgcctcca acctgatccc tgtgatcgct gccaacagaa tcggtgagga aacagtagag
     6721 ccatgtccgg aaaacggaat gcagaaatct gctcttaatt tttacggttc ctcttttatt
     6781 acagataaca caggtgctct ctgcgcagaa ctgcccggag gagaagaggg ggtgcttgta
     6841 agcacttttg acctggatgc attaaaggca gacagactga actggggact tttcagagac
     6901 cgcagacc
//
