LOCUS       c00010_gnlPro..        14552 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FHEAOIEN_10.
ACCESSION   c00010_gnlPro..
VERSION     c00010_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:24:51
            Original ID  :: gnl|Prokka|FHEAOIEN_10
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 66877
            Orig. end    :: 81429
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14552
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[76877:81161](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14284
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..14552
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14552
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(564..2048)
                     /locus_tag="ctg10_60"
                     /transl_table=11
                     /translation="MEKLQARKKVYLWLLILLSLCALIPLAVLSKYNHQSGDDYGYAYR
                     TFQIWRETHSFWNVIKEAFATSAEFYQKWQGLYASAVLLALEPGIFGDKYYALTGILLL
                     AIIVGANCAGTVYIFHRKCGCPRLEGFAAGCVMSFLMIEWMPSALQGLYWYNGAMNYVF
                     FHAVLLLLLCVLLSLAGEHPRRKAGRTVLAVLLAVLLAGGNHVTAFMGILLIVGFGIFA
                     AVKKRRQNLICCVITLAAMVAGFLFNVTSPGTRIRQSYFSDRPGVAGTIVTAVKTGIAC
                     INSWMGLAVIVTAVLLLPVLLPLVKKIRGQYGFSFRYPLLVFVLSVAWLCAMFCPPIYA
                     MGTPGDVRLTNVVYFSFVWLFVLNEAYLCGWAVTRLEASGAAALSGAAGEFPGSFLITA
                     AVLAVGMIIGCGENMTAWQAYLLIRSGEAQEYSAEADERYAVLCDSAGEDVVLKAYTAK
                     PWMLFLDDITEEKSDWRNEYMRVYFGLNSVVLEQTE"
     CDS             complement(2058..4553)
                     /locus_tag="ctg10_61"
                     /transl_table=11
                     /translation="MKSKKNTFVSRAAVGCVTTAIFLLLCIIKGIYPFGIATLDTVDFQ
                     SQWIPAYYHVWDVLHGDGSAFFDWRVGGGNNFAGVSAQFSLFSPFNLFFLFVKRSWIEK
                     SMIVFLLIKLLAMGYGMRWFLKEQILKEERYGIYILAGSVGYAVNGYTLLYYGMGWLDV
                     AAILPLLCYFFCRMAEREGDWRLGKNTLGYIVCLTLVFLINIPQAYMMCFFLIVFAGGY
                     FFLKRQDQPLKKNGILKFGLTSLLSLGIAAVIFLPAARAMLGSYRLSGEEYRGISGYFL
                     LLRQDGMDAVWKWVILGSVAVPLLFFVISGRRKREHIWQWYLVAAMVLPVFFEAVNLIW
                     HRGTYVCFPMRYGYMLVFAVICMAAARVPDFVGDSRVRRNILYAFLGIWCVQMVALGIS
                     LIQPETHTDETDFVGDATEIGQPLAGKTDVFHKAKLADGAIDNNYPLIAESTSYSNYLH
                     LMTSEQIRMNTLLGYSQVWTRLSDTGGTLASDIMLGYRYYVASKAGSWGKDTAADSLWP
                     LAETEKFTLWENAPVGDRAFFITKADYEAYVVTEAYTENVFENQNRLSELLFHTVPIDW
                     KKETYLDDQTGAELSYRFYADGKQILYLYGKDLQQAEITVNGERLYVPDYNDLYNESYP
                     ATGNQGILSLGCFSDEDITVEIRQSVGDSGAERAVFFGFLDPQELLEAVDAAGRAVTYE
                     LARDSCKLTVESAGAEYLMLPVNADSGWHCTVNGEERAISRLAGNLMLVPLDEGTNEIT
                     LCYVPRGMKKGAAVTGMALMLLAGWGVLSRLLRRKSVLDKIYAGLGCAAADIFAVVYAG
                     FLLVVYVIPVVYTIYLRWI"
     CDS             complement(4642..4908)
                     /locus_tag="ctg10_62"
                     /transl_table=11
                     /translation="MVVWLVILFAFMYFFMVRPQKKEQQKKNSMLAELAVGDTILTTSG
                     FYGTVIDIADDTVIVEFGSNKNCRIPMQKAAISAVEKPEDVTE"
     CDS             complement(5058..6209)
                     /locus_tag="ctg10_63"
                     /transl_table=11
                     /translation="MYELLKQEGRAKRGVFHTVHGDIQTPVFMNVGTVAAIKGAVSTED
                     LEQIKCQVELSNTYHLHVRTGDKLIKEVGGLHKFMSWNRPILTDSGGFQVFSLAGLRKI
                     KEEGVYFHSHIDGAKIFMGPEESMQIQSNLGSTIAMAFDECPPALAERKYVEDSVARTT
                     RWLERCKNEMQRLNGLEDTVNRHQMLFGINQGAVYTDIRIDHAKRISEMDLDGYAVGGL
                     AVGETHEEMYHVLDETVPYLPVNKPTYLMGVGTPANILEGVERGIDFFDCVYPSRNGRH
                     GHVYTNQGKINLFNQKYEKDMRPIEEGCGCPTCRRYSRAYIRHLLKAKEMLGMRLCVLH
                     NLYFYNTMMEEIRDALDAGNFASYKEEKLYGMGQINREKEMEK"
     CDS             complement(6256..7581)
                     /locus_tag="ctg10_64"
                     /transl_table=11
                     /translation="MIEKYLVKKITEPVDWKVTVPGSKSMTNRALLMAVLSAGTVRVEG
                     VLFSDDSRHFLACLVALGFTVEIEEEKKCVTVTGCGGRIPRGEAVIDVGSAGTAARFLA
                     AMLGFSDGCYEIRCSAQMKRRPMAELFDLLSGAGAKITFLEEEGHLPVRITGCRYARAD
                     KTAGETPRELSLDITKSTQFLSALLLIAPMVPEGMKIHITSEKTDGSYIRITRKMMQEF
                     GVSVAFDGRDYEVPCRSSYRKETYMVEPDMSAACYFYAAAAVTGGRALVRHVHMDNTQG
                     DLRFLEVLEHMGCTADDTPEGVLVTGPADGALRGITVNMNDFSDQALTLAAIAPFADAP
                     VRIEGIGHIRGQECDRIHAIQTNLTALGIRCEEEETAATIYPGSPHGGSVETYDDHRVA
                     MAFSLVGLRTDGIVIENPACCRKTFENYFTVLSELTGKKTEA"
     CDS             7706..8806
                     /locus_tag="ctg10_65"
                     /transl_table=11
                     /translation="MAGSTLGTLFKITTWGESHGKGVGVVIDGCPAGLSLCEADIQKFL
                     DRRKPGQSRYATPRKEDDAVEILSGVFEGKTTGTPISLVVFNRNQQSKDYSEIASYYRP
                     GHADYTFDQKYGFRDYRGGGRSSGRETIGRVAAGAVAVKILNELGITFITYTKSIGPIA
                     VSSDRFNFSEVTKNPLYMPDAEAAENAENYLDACMAELNSSGGIVECIIKGMPAGIGDP
                     VFEKLNANLAKAVMSIGAVKGFEIGDGFDVAKATGKNNNDAFVLGENGRIAKATNHAGG
                     ILGGMSDGSDIILRAAIKPTPSIAATQRTVNQSGEEISVNIKGRHDPIIVPRAVVVVES
                     MAAITIVDALFSNMSARMDALKDFYS"
     CDS             complement(8882..9739)
                     /locus_tag="ctg10_66"
                     /transl_table=11
                     /translation="MNWLNKLERKFGNWAIPNLIVWLIGAYTIGFVLYQVNPSIIGLLM
                     LSPYHILHGQIWRLITWVFMPTDTNLVYLLIMALFYYQLGTTLERTWGTFRFNVYIFGG
                     MLFTVIGAFLLYGIMYLMNGGVTTEMLLIGTSFSTSYINMSIFLAFACMYPDMQVLLMF
                     IIPIKMKWMAAVYGVLIALSFFETGWAGRMAIFMSLLNFIIFFFSTRNLKRYTPHEVHR
                     RQKFKADMRRPQGYAGGAKHKCAVCGRTELDDPTLEFRFCSKCEGNYEYCQDHLFTHQH
                     IRMS"
     CDS             10001..14284
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_67"
                     /sec_met_domain="HGD-D (E-value: 7e-60, bitscore: 195.5,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.2e-37, bitscore:
                     121.9, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNTLHKLGIDIGSTTVKVAILDQEDHLLFSDYERHFANIQETL
                     SSLLQKAYDALGDFAVAPMITGSGGLTLAKHLGVPFVQEVIAVSTALQHYAPQTDVAIE
                     LGGEDAKIIYFEGGNVEQRMNGICAGGTGSFIDQMASLIQTDATGLNEYAKNYKAIYPI
                     AARCGVFAKTDIQPLINEGATREDLSASIFQAVVNQTISGLACGKPIRGHVAFLGGPLH
                     FLSELKAAFIRTLNLDNEHTITPENSHLFAAIGSALNYKPGETTTLVSLRDRLSNGIKM
                     EFEVARMDPLFASQEEYDAFRARHDGHNVKSADLSTYEGNCYLGIDAGSTTTKIALVGE
                     DGSLLYSFYSNNNGSPLATAIRSIKEIYTLLPPKAKIVHSCSTGYGEALLKAALMLDDG
                     EVETVAHFYAAAFFDPEVDCILDIGGQDMKCIKIKNQTVDSVQLNEACSSGCGSFIETF
                     AKSLNYSVQDFAKEALFAKNPIDLGTRCTVFMNSKVKQAQKEGASVADISAGLAYSVIK
                     NALFKVIKLSDASQLGKNIVVQGGTFYNDAVLRSFEKIAGVECVRPDIAGIMGAFGAAL
                     IARERHEADYQTSMLSIEQINALTFDTKLARCQGCTNHCLLTINRFSGNRQYITGNRCE
                     RGLGKEKNKDNIPNLYEYKNKRLFDYTPLSAEEAARGTVGIPRVLNMYENYPFWATFFK
                     KLGFSVVLSPQSTRKIYELGIDSIPSESECYPAKLAHGHVTWLIHQNVDFIFYPCIPYE
                     RNEFPDSNNHYNCPIVTSYAENIKNNVDEITSGQVKFLNPFMSFASEETLSSQLIKTFG
                     QSEFGIPESEIRDAVAEGWKELAVCRMEMQKKGEEVLQYLKETGRRGIVLAGRPYHVDP
                     EINHGIPELITSYGIAVLTEDSISHLQPVERPLIVMDQWMYHSRLYAAANYVKTRDDLD
                     LIQLNSFGCGLDAVTTDAVNDILTKSGKIYTCLKIDEVNNLGAARIRIRSLISAIRVRE
                     KKQTKRTIVPANYNRVVFTEEMRKNYTILCPQMSPIHFELLEPAFQTAGYNLVVPDVDS
                     HTCVDVGLKYVNNDACYPSLIVVGQLMAAVMSGDYDMSRTAILISQTGGGCRASNYIGF
                     IRRALEKAGYPDVPVISINLSGLEKNPGFKLTLPLIQHGLYALEFGDIFMRCVYATRPY
                     EAVAGSTDELHEKWKKEVIAFITQKKMLSHGKFKKMCREIIRDFDNLPRKDIKKPRVGV
                     VGEILVKFHPAANNHLVELLESEGAEAVVPDLTDFLLYCFYNTGFKADNLGMSQKSKKI
                     GRLGINFFEWLRSAARDEFTKSRHFTAPAHIDDLARYARDIVSEGNQTGEGWFLTGEML
                     ELIHTGTPNIVCTQPFACLPNHVVGKGVIKELRHRYPGSNIVAIDYDPGASEVNQLNRI
                     KLMLSTANKNLAKQNAPEQKDQAAG"
ORIGIN
        1 ttcttcatat aaatatgccg gtcttaagtt ggcaaacagg ttcagcgcct tgcggagctt
       61 taaaagtccc gcctccggtc tcttctccgg cggcagctga taccacggcg aagtcgatgt
      121 gttgccgccg atcgatccca tcagcaccgc atcggaagcc ttcgcggaag cgatcgccgc
      181 atccgtgagc ggctcacccg tcgcgtcaat ggagcagcct cccatcagaa tctcttcata
      241 gcggaacaca tgtccgtagg tctttccaat ctgatccaga actttctttg cctctgttac
      301 gatctccggt ccgatcccgt cgccggaaat cacgcctacc ttatattcca tctctctaat
      361 ccctcttttc ttcctgccgt gcaggaatcc gtcttgtatt gactttagta cattactaac
      421 agacagtata taaattctat aataatgtat ctcgggaaac aatgcaacct ctgaatctat
      481 ttttcttttt catactccct ataaccgggt cttatgaaaa aggagcagcc tgccttttgt
      541 gtccgctgct cccttttgcc gtctcattcc gtctgctcta acacaacgct gttcagtcca
      601 aaatagacgc gcatatattc atttctccag tcgcttttct cctctgtaat atcgtcgagg
      661 aaaagcatcc acggctttgc ggtatacgcc tttaacacca cgtcttcccc cgcagaatca
      721 cacaaaacgg cgtagcgctc atcagcctcc gccgaatatt cctgtgcctc gccgctgcgg
      781 atcagcaggt atgcctgcca tgcggtcata ttttccccgc atccgattat cattcccacc
      841 gcaaggacag cagccgtgat caaaaaactg cccggaaatt ctcctgcagc cccggacagt
      901 gctgccgccc cggacgcctc cagtcttgtg accgcccatc cgcacagata ggcttcattt
      961 aacacaaaca gccaaacgaa ggaaaaatat accacgtttg tcagccggac gtcccccggc
     1021 gttcccatcg cgtagatggg cgggcagaac attgcgcaca gccaggcgac cgacaacaca
     1081 aagacaagca gcggatagcg gaacgaaaat ccatactgtc cgcgtatctt ctttaccagg
     1141 ggaagaagca ccggaagcag caggaccgcc gtgacaatga ctgcaagtcc catccagctg
     1201 ttgatgcatg caattccggt ttttaccgcg gtaacaatcg ttcccgccac accgggtctg
     1261 tcggaaaaat acgactgccg gattctggtg cccggcgacg tcacattaaa aaggaatccc
     1321 gccaccatag ccgcaagcgt tatgacgcag cagatcaggt tctgccgccg cttttttacc
     1381 gcagcaaata ttccaaatcc gacaatcagc agtatcccca taaatgcggt cacgtgattc
     1441 ccgccggcaa gcagcaccgc aagcagcacc gcaagcaccg tcctgcctgc ttttctccgc
     1501 gggtgctccc cggcaaggct gagcagcaca cacaacaaca ataatagcac cgcatggaag
     1561 aatacataat tcatcgcgcc gttataccag tacaatccct gcagggcgga gggcatccat
     1621 tcgatcataa gaaacgacat gacacagccg gcagcaaatc cctccagtct cgggcagccg
     1681 catttgcggt gaaagatata aaccgtaccc gcgcagtttg cccccacaat aattgcgagc
     1741 agcaagattc cggtcagcgc gtaatatttg tcgccgaaaa ttcccggttc cagcgccagc
     1801 agaaccgccg atgcataaag cccctgccac ttctgataga actccgctga tgtggcaaac
     1861 gcttctttta tcacattcca gaaagaatgt gtctcccgcc agatctggaa ggtgcggtag
     1921 gcataaccat agtcatcccc cgactgatga ttgtacttcg agagtacggc taacgggatc
     1981 agcgcgcaaa ggctcaataa aatcagcagc cacaaatata ctttttttct cgcttgtaat
     2041 ttttccattc tgttacctca gatccatctt aaatatatcg tatacaccac cggaatcaca
     2101 tagacgacca gcagaaatcc ggcatagacc accgcaaaaa tatctgcggc ggcacagcca
     2161 agtccggcgt agattttatc caggacactt tttctccgaa gcagacgtga taaaacgccc
     2221 cagccagcca gaagcatcag tgccatgccc gtcaccgccg cgcccttttt cattccccgc
     2281 ggcacataac aaagcgtaat ctcattcgta ccctcgtcaa gcggcacgag catcagattg
     2341 cccgcgagcc ggcttatggc ccgctcctct ccgtttaccg tacaatgcca tccgctatcc
     2401 gcattgaccg gaagcatcag atactccgct cccgccgatt ccacagtaag cttacaggaa
     2461 tcccgagcca gttcatatgt aaccgccctt cccgctgcat ccaccgcctc cagcagttcc
     2521 tgcggatcga ggaatccgaa gaacaccgct ctctctgcgc cgctgtcccc aacagactga
     2581 cggatttcca ccgtgatgtc ttcgtccgaa aaacacccga gggagaggat tccctgattg
     2641 ccagttgccg ggtagctctc attgtacaga tcattgtaat ccgggacgta gagcctctcc
     2701 ccgtttaccg taatttctgc ctgctgcaga tcctttccat agagatataa gatctgcttt
     2761 ccatccgcgt aaaaccggta cgataattcc gctccggtct gatcatccag ataggtctct
     2821 tttttccagt caatgggaac tgtgtgaaaa agcagctccg acagccggtt ctggttctca
     2881 aacacatttt ccgtgtacgc ttccgtgact acatacgctt catagtccgc ttttgtgata
     2941 aaaaatgccc tgtccccgac gggcgcattt tcccacagcg taaacttttc ggtctcagca
     3001 agcggccaaa gggaatccgc cgccgtgtct tttccccacg atcccgcctt agacgccaca
     3061 taataacggt accccagcat gatgtcggac gcgagcgttc cgcccgtgtc acttaatctg
     3121 gtccacacct gagaataccc gagcagtgtg ttcatcctga tctgctccga cgtcatcaga
     3181 tgcagataat tggagtagga ggtgctctct gcgatcagcg gatagttgtt gtcaatcgct
     3241 ccgtccgcca gctttgcctt gtggaaaaca tcggtttttc ccgcaagcgg ctgaccgatt
     3301 tccgtggcat ccccaacaaa atccgtctcg tccgtgtgcg tttccggctg tatcaaagaa
     3361 atgccaagcg ccaccatctg cacgcaccag attcccagga acgcatataa aatgttccgc
     3421 cgcacgcggc tatctcccac aaaatccggc acgcgcgccg ctgccataca aatcacggca
     3481 aacaccagca tataaccata tcgcatcggg aagcacacat acgtcccgcg gtgccagatg
     3541 agattgaccg cctcgaagaa aaccggcagc accatcgccg ccaccagata ccactgccag
     3601 atgtgctccc gcttccgtct gccagaaatg acgaagaaca gcagcggaac cgccacgctg
     3661 ccaagaatca cccatttcca caccgcgtcc attccgtcct gccgaagcag cagaaaatag
     3721 ccggagattc cccggtactc ctcgcccgac agccggtagg aaccaagcat tgccctcgct
     3781 gccggcagaa atattaccgc cgcaattcca agcgacagta aagaagtcag cccgaatttt
     3841 aaaatgccgt tcttttttag cggctggtcc tgtcgtttca ggaaaaaata tccccccgca
     3901 aacacgatca ggaaaaaaca catcatgtac gcctgcggaa tattgatgag gaataccagc
     3961 gtcaggcaga cgatatagcc gagcgtattt ttcccgagac gccagtcccc ttcccgctcc
     4021 gccatcctgc agaagaaata acacaatagc ggcaggatcg ctgccacatc cagccagccc
     4081 atgccatagt acaaaagcgt atagccgttt acggcatacc ccacgcttcc cgccagaatg
     4141 tagattccgt aacgctcttc cttaaggatc tgctctttta aaaaccagcg catgccatag
     4201 cccatggcaa gcagcttgat taaaagaaac acgatcatgg atttttcaat ccagcttctt
     4261 ttcacaaaga ggaagaacag gttaaacggg ctgaacagag aaaactgcgc gctcactccc
     4321 gcaaaattat tcccgccgcc gactctccag tcaaaaaagg cgctgccgtc tccgtgcagc
     4381 acatcccata catggtaata tgccggaatc cactgggact gaaaatccac agtgtcaagc
     4441 gtggcaattc caaacggata gatgcccttt atgatgcaca acagcagaaa aatggcagtt
     4501 gtcacgcagc cgacggcggc acgtgaaaca aacgtatttt ttttactttt catccggaca
     4561 atctctcctc gctctccgaa atactctctc aaaaagaaaa gggataatac attttatata
     4621 ctatccctct taaaaatctt cttattcagt tacatcttcc ggcttctcca ctgcggaaat
     4681 agctgccttc tgcatcggaa tacggcagtt cttgttgctt ccgaactcaa cgattactgt
     4741 atcatcagca atatcgatca cggttccata aaaaccgctt gttgttaaga tcgtatctcc
     4801 cactgcaagt tctgcaagca tggagttctt cttctgctgt tccttcttct gcggacgaac
     4861 catgaagaaa tacataaacg caaataaaat aaccagccac accaccatac tgatccagcc
     4921 agcggatgac gcactctctg ttgctaagat tgaaaacatc tgatatcctc ctaaaatcat
     4981 aaacttgtcc gaagtcatcc gacttcatta aagagtattg tacacaaaac ctcgctgttt
     5041 ggcaagcctt ttccctctta cttttccatt tccttttccc ggttgatctg tcccatgccg
     5101 tataactttt cttccttgta ggaggcaaaa tttccggcat ccagcgcatc ccggatctct
     5161 tccatcatcg tgttgtagaa gtacagattg tgcagaacac ataagcgcat gccaagcatc
     5221 tcttttgcct tgagcagatg acggatatag gctctgctgt agcggcggca ggtcgggcag
     5281 ccgcagccct cctcgatcgg acgcatatcc ttctcgtact tctggttgaa caggttgatc
     5341 ttgccctggt tcgtgtatac gtgaccatgg cggccgttgc gggacgggta gacacaatca
     5401 aaaaagtcaa tgccgcgctc cactccctct aaaatattgg ccggcgttcc gactcccatg
     5461 agataggtcg gcttgttcac cggaagatac ggaacggtct catccagcac atggtacatc
     5521 tcctcatgtg tctcaccgac cgcaagtccg ccgaccgcgt agccgtccag atccatctcg
     5581 gaaatccgct tggcatggtc gatccggatg tccgtataga cggctccctg attgatgccg
     5641 aacagcatct ggtgacggtt cacggtatcc tccagcccgt tgaggcgctg catctcgttc
     5701 ttgcagcgct ccagccaacg tgtcgtccgt gccacggaat cctccacata tttccgctcg
     5761 gcaagcgccg gcggacattc atcgaacgcc atagcgatcg tggaaccgag attggactgg
     5821 atctgcatgc tctcctccgg tcccatgaaa atctttgcac cgtcaatatg cgagtggaaa
     5881 tagacgccct cctccttgat cttgcgcagg cctgccaggg agaacacctg aaatccgccg
     5941 gaatccgtaa gaatcggacg attccacgac ataaacttgt gcagtcctcc cacttccttg
     6001 atcagcttgt ctccggtgcg cacatgcaga tggtaggtgt ttgacagctc cacctgacat
     6061 ttgatctgct ctaaatcttc cgtggagaca gctcccttga tggcagccac cgtacccaca
     6121 ttcataaata ccggcgtctg gatatctccg tgcaccgtat ggaaaacgcc tctcttcgcg
     6181 cgtccttcct gttttaataa ttcatacatc tgtttttcgt ctccttttta ttactcctgc
     6241 aaagccggcg ctgcttcacg cctccgtctt cttcccagtc agttcgctta acacggtaaa
     6301 ataattttca aacgtcttgc ggcagcacgc cgggttctca atgacaatcc cgtcggttct
     6361 tagtccgacc agggaaaatg ccatcgccac gcggtgatcg tcgtatgtct ccacgcttcc
     6421 gccgtggggg ctgccgggat agatcgtggc agccgtctct tcctcctcac accggatgcc
     6481 aagcgctgtc aggttcgtct gtatcgcgtg aatccggtcg cattcctgcc cacggatatg
     6541 tccgattccc tctatgcgca ccggcgcgtc ggcaaacggc gcgatcgccg ccagagtcag
     6601 cgcctgatcg gaaaaatcgt tcatattgac tgtgatgccc cgtagcgcac cgtccgccgg
     6661 ccccgttacc aggacgccct ccggcgtatc gtccgcggta catcccatgt gctccaacac
     6721 ttccaggaaa cgcagatctc cctgtgtgtt gtccatatgc acatgccgca caagcgcccg
     6781 tccgccggtc acagccgcag ccgcataaaa atagcaggca gccgacatat ccggttccac
     6841 catataagtc tctttccggt aggaacttct gcacggcacc tcgtagtctc ttccgtcaaa
     6901 agcgacactc acgccgaatt cctgcatcat cttccgcgtg atgcggatgt atgagccgtc
     6961 cgtcttctca ctggtgatgt ggatcttcat cccttccgga accatcggcg caatcaacag
     7021 cagcgcgctt aaaaactgtg tgctcttcgt aatgtcaaga gagagctccc gcggcgtctc
     7081 ccctgccgtc ttatccgccc gggcgtatct gcatcctgtg atgcgcaccg gaagatgccc
     7141 ttcctcctcg aggaaggtaa tcttcgctcc cgcaccggaa agcagatcga acagctccgc
     7201 catcggccgc cgcttcatct gcgctgagca gcggatctca tagcacccgt ccgaaaatcc
     7261 gagcatcgcc gcaagaaaac gcgccgctgt cccggcgctt ccgacgtcga ttaccgcctc
     7321 cccgcgggga atcctgccgc cgcagcccgt cacggtcacg cacttttttt cttcctctat
     7381 ctccactgta aagccgagcg ccacaagaca cgccagaaag tgtctggaat catcggaaaa
     7441 caggactcct tccacgcgca ccgtccctgc ggacagcact gccataagaa gcgcgcggtt
     7501 cgtcatgctc ttcgatcccg gcacggttac cttccagtcc accggctctg ttatcttttt
     7561 cacaaggtat ttctctatca tgaaatattc ttctcctcgc ctgctggtac ttctgctccg
     7621 tcaaatcata acatatttct gttgcggcgc aaagtcaaat cttttataat cgagaaagat
     7681 cattatgtaa gcaggaggga atcacatggc aggttctact ttgggaactc tttttaaaat
     7741 cacaacctgg ggggaatctc acggaaaggg cgtcggcgtc gtcatcgacg gctgtccggc
     7801 gggactttct ctctgtgagg cggatatcca gaagtttctc gaccggcgca agcccggtca
     7861 gtccagatat gcaacgccgc gcaaagagga cgacgccgta gagattctct ctggcgtgtt
     7921 tgaaggaaag acgaccggca ccccgatctc gcttgtcgtc ttcaaccgca accagcagtc
     7981 caaagactac agcgagattg cctcctatta ccgtcccggt cacgccgatt acacgttcga
     8041 ccagaaatac ggcttccgcg actaccgcgg gggcgggcgc tcctccgggc gggaaaccat
     8101 cgggcgtgtc gccgccggcg ccgtcgccgt caagattcta aacgagctcg gcattacctt
     8161 tataacctac acaaaatcca tcggcccgat cgccgtatct tccgatcgtt ttaatttttc
     8221 cgaagtcacg aagaatccgc tctatatgcc ggacgccgag gcagccgaga acgccgaaaa
     8281 ctatctggat gcctgcatgg cggaactgaa ttcctccggc ggcattgtgg agtgtatcat
     8341 aaaggggatg cccgccggca tcggagatcc ggtcttcgag aagcttaatg cgaaccttgc
     8401 caaggcggtc atgtccatcg gtgccgtcaa aggttttgag atcggggacg gatttgacgt
     8461 agcaaaagcg accggcaaga acaacaacga tgcctttgtc ctcggtgaga acggcaggat
     8521 tgccaaagca accaaccatg ccggcggtat cttaggcggc atgagcgacg gaagcgacat
     8581 catcctccgg gctgccatca agccgacccc ttccatcgcc gccacacagc gcactgtcaa
     8641 tcagtccggg gaggagatct cggtcaacat caagggacgc cacgatccga tcatcgttcc
     8701 gcgcgccgtt gtcgtggtgg aatccatggc agccatcacg atcgtcgacg cacttttttc
     8761 caatatgagt gcacggatgg atgcgctaaa agatttctac tcctaaaagg aagaaaaagg
     8821 tgatactttt tctccgccgg ctggcggaat cgaagtatca cctttttctt tttcatactt
     8881 tctagctcat ccgaatatgc tgatgtgtaa acagatgatc ctgacagtat tcgtaattgc
     8941 cctcgcactt ggagcagaaa cggaattcca gcgtcggatc gtcaagttcc gtcctgccgc
     9001 agacagcaca cttgtgcttc gcaccgcccg catatccctg cggtcttcgc atgtctgcct
     9061 taaacttctg gcgcctgtgc acctcgtgcg gcgtatagcg cttgaggttt ctggtggaga
     9121 agaagaaaat aataaagttg aggagcgaca taaaaatcgc cattcttccc gcccatccgg
     9181 tctcaaaaaa gcttaaagca atcagaacgc cgtacacagc cgccatccac ttcatcttaa
     9241 tcgggataat gaacatcaga agaacctgca tatccggata catacatgca aacgcaagga
     9301 agatggacat gttgatgtaa cttgtgctga aactcgttcc gatgagaagc atctccgtcg
     9361 tcacaccgcc gttcatcaga tacatgatac cgtacagcag aaacgctccg atgacggtaa
     9421 acagcatacc tccgaaaata tagacgttaa accggaaggt tccccaggtg cgctccagcg
     9481 tcgttccaag ctgataatag aaaagcgcca tgatcaaaag atacaccaga ttcgtatctg
     9541 tgggcataaa cacccaggta atcaggcgcc agatctgccc gtgcaggatg tgatacgggc
     9601 tcaacatcaa aagtcctatg atcgacggat tcacctggta gagcacaaat ccgatcgtgt
     9661 aagctccgat cagccacacg atcagattgg gaatcgccca gttgccgaat ttacgttcta
     9721 atttatttaa ccagttcata tactctgtcc ctgacctttc caaaaatgac attacgtttt
     9781 tcagtatatc ggtcagggaa atctttgtca atcagagggg tttttcttta caaaaagttt
     9841 atacttttcc ggcaaaatgc acattgtctt ttgacatatc ctgtcgtata atgtagagtg
     9901 tttagcgcca gattggcact atttataata agaagaaatc ttttacatat tttactctgc
     9961 taaagtattt actttacgag aaacaaccat ggagggaatt atggaaaaca atacacttca
    10021 taaattggga atcgacatcg gttccacaac cgtcaaggtc gcaattttag accaggagga
    10081 tcatctgctc ttctctgatt atgagcgcca ttttgccaat atccaggaga ccttatcctc
    10141 ccttctccag aaagcttacg atgcccttgg cgactttgct gtcgctccga tgattaccgg
    10201 ttccggcggc ctgaccctcg ccaagcacct cggcgttccg tttgtccagg aagtgatcgc
    10261 cgtatccacc gccttacagc actatgcgcc gcagacagat gttgccatcg agctcggcgg
    10321 tgaggacgcc aagatcatct attttgaggg cggcaatgtc gagcagcgta tgaacggtat
    10381 ctgcgccggc ggtaccggat cttttatcga ccagatggcg tccctcatcc agacggatgc
    10441 gaccggtctg aatgaatacg ccaagaatta caaggcaatc tacccgatcg ccgcgcgctg
    10501 cggcgtcttt gccaaaactg atatccagcc gttaatcaat gagggggcta ccagggaaga
    10561 tctgtctgcc tccattttcc aggcggtggt caatcagacg atcagcgggc ttgcctgcgg
    10621 taagccgatc cgcggccacg ttgcctttct cggaggtccg cttcatttcc tctccgagct
    10681 caaggctgct tttatccgca ccctgaatct ggacaatgaa cacaccatca caccggagaa
    10741 ttcgcatctg ttcgcggcga tcggttccgc gttgaactac aagccgggcg agacaaccac
    10801 gctcgtctct ctccgcgacc gtctctcgaa cggcatcaag atggaatttg aggttgcccg
    10861 tatggatcct ctgtttgcca gccaggaaga atacgacgct ttccgcgcac gtcacgacgg
    10921 gcacaatgtc aagtccgcag atctctccac ctacgagggc aactgctatc tgggcatcga
    10981 tgcaggttcc accacgacca agattgcctt agtcggcgag gacggttccc ttttgtattc
    11041 tttctacagc aacaacaacg gaagtccgct tgcgacggca atccgttcca tcaaggagat
    11101 ctatacgctc cttccaccga aggcaaagat cgttcactcc tgctccaccg gatacggtga
    11161 agcgctgtta aaagccgctt tgatgctcga tgacggcgag gttgagacgg tggcacattt
    11221 ctatgcagcc gcgttcttcg acccggaagt cgactgtatc ttagacatcg gcggtcagga
    11281 tatgaaatgt atcaagatca agaatcagac ggtggattcc gtacagctca atgaggcttg
    11341 ttcctccggc tgcggttctt tcatcgagac gtttgcaaaa tccctcaact actctgtaca
    11401 ggattttgca aaggaggctc tttttgccaa aaatccgatc gatcttggaa cccgttgcac
    11461 cgtatttatg aattccaagg taaagcaggc gcagaaagag ggcgcatccg ttgcagatat
    11521 ttctgcgggt cttgcgtact ctgtcatcaa gaatgcttta tttaaggtaa tcaagctttc
    11581 cgatgcaagc cagctcggga aaaatatcgt cgtacagggc ggtacgtttt acaacgatgc
    11641 cgtactgcgc agttttgaga aaatcgcggg tgtcgaatgt gtccgtccgg atattgccgg
    11701 catcatgggt gctttcggtg ccgcactgat cgccagagag cgtcacgagg cagactacca
    11761 gacctccatg ctttccatcg aacagatcaa tgcgctgacc ttcgacacaa agctggcaag
    11821 atgtcaggga tgtaccaacc actgtctcct cacaatcaac cgcttttccg gcaaccgcca
    11881 gtatatcacc ggcaaccgct gtgagcgcgg cctcggcaag gagaaaaata aagacaacat
    11941 tccaaacctc tacgaataca agaacaaacg cctgtttgac tacaccccgc tttccgccga
    12001 ggaagcagca cgcggcacag tcggtattcc gcgcgtttta aatatgtacg agaactaccc
    12061 gttctgggca actttcttta agaagctcgg tttttccgtg gtactctccc cgcagtcgac
    12121 gcgcaagatc tacgagcttg gaattgattc catcccgagc gagtccgagt gctacccggc
    12181 aaagctggca cacggtcatg tgacatggct gatccaccag aacgtcgatt ttattttcta
    12241 cccgtgtatt ccttatgagc gcaacgaatt cccggattcc aacaatcact acaactgtcc
    12301 gatcgttacc tcctacgcgg aaaatatcaa aaataacgtg gacgagatca cttccggtca
    12361 ggtgaagttc ttaaatccgt ttatgtcttt cgccagcgag gagacgcttt cctcccagct
    12421 gattaagacc tttggccagt cggagttcgg gattccggaa tctgagatcc gcgacgcggt
    12481 tgccgaaggc tggaaggagc ttgccgtctg ccggatggag atgcagaaaa aaggcgagga
    12541 agtcttacag tatttaaagg agaccggaag acgcggtatc gtcctcgcag gtcgtccgta
    12601 ccatgtagac cctgagatca accacggtat tccggagctg attacctcct acggcatcgc
    12661 cgtgctcacg gaggattcca tctcccactt acagccggtg gagcgcccgc tcatcgtcat
    12721 ggatcagtgg atgtatcact ccagactgta cgcagcggcg aactatgtca agacaagaga
    12781 cgatctcgac ctcatccagc tgaattcctt cggctgtggt ctggacgccg tcacgacaga
    12841 cgctgtcaat gatattctga caaagtccgg caagatctac acctgcttaa agatcgatga
    12901 ggtcaacaac ctcggtgcgg cgcgcatccg tatccgttcc ctgatctcgg cgatccgtgt
    12961 ccgtgagaag aagcagacga agcgcaccat cgttccggcg aattacaacc gcgtcgtctt
    13021 cacggaggaa atgcgcaaga attacaccat cctctgccca cagatgtcac cgatccattt
    13081 tgagctgttg gagccggcgt tccagacggc cggatacaac cttgttgttc cggatgtgga
    13141 cagccacacc tgcgtggatg tcggcttaaa gtacgtcaac aacgacgcct gctacccgtc
    13201 cctgatcgtg gtcggccagc tgatggctgc tgtgatgtcc ggcgattatg atatgtcgcg
    13261 caccgcgatc ttaatctccc agaccggagg cggctgccgc gccagcaatt acatcggctt
    13321 catccggcgt gcactggaaa aagccggcta tccggacgtt ccggtcatct cgatcaatct
    13381 gagcggtctg gagaagaacc cgggctttaa gctgacactg ccactgatcc agcacggact
    13441 ctacgcgctg gagtttggcg atatcttcat gcgctgcgtc tacgcaacgc gcccttacga
    13501 ggcggttgcc ggatcaacgg acgagttgca tgagaaatgg aaaaaagagg ttatcgcctt
    13561 tattacccag aaaaagatgc tctcccacgg caagttcaag aaaatgtgcc gcgagatcat
    13621 ccgcgatttt gacaaccttc cgcgcaaaga catcaagaaa ccgcgcgtcg gcgttgtcgg
    13681 cgagattctt gtcaagttcc atccggctgc caacaatcat ctggtggagc ttctcgaatc
    13741 cgagggtgca gaggccgttg taccggatct gaccgatttc ctgctctact gcttctacaa
    13801 tacgggcttt aaagcagaca atctcggcat gagccagaag tccaagaaga tcggccgtct
    13861 gggcatcaat ttctttgagt ggctgcgcag cgctgcaaga gatgaattca caaagagcag
    13921 gcactttact gcacctgcgc acatcgatga tcttgccaga tatgcaagag acattgtatc
    13981 cgagggcaac cagaccggcg agggctggtt cttaaccggt gagatgttag agctgatcca
    14041 caccggaaca ccgaacatcg tctgcacgca gccgttcgcc tgcctgccga accatgtggt
    14101 cggcaagggc gtcatcaagg aactgcgtca ccgctatcct ggttccaata tcgtggccat
    14161 cgattacgat ccgggtgcca gcgaggtaaa ccagctcaac cgtatcaagc tgatgctctc
    14221 caccgcgaac aaaaatctgg caaagcagaa cgcaccggag cagaaggatc aggctgcagg
    14281 ctgacagata cagagaaagg ggctgcgcat caaatgtgca gccccttttc gtgataagta
    14341 atattacagg aatactagag aacaaaaaag ttccagaata aacagacggc ggcaaattct
    14401 ttgaagcaaa attcgagtat ttcttccata ccgccgctgg catcccattc cgtgtctttg
    14461 ccacgtttgg acactcacgg agtgtgtccg acaagctgca gacaatgagc ggactttctg
    14521 gtgtccctaa tggcacctct tcacagacaa ta
//
