LOCUS       c00016_gnlPro..        31189 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FHEAOIEN_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:24:51
            Original ID  :: gnl|Prokka|FHEAOIEN_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 24978
            Orig. end    :: 56167
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..31189
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[34978:46167]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..21189
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
     cand_cluster    1..31189
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="chemical_hybrid"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..31189
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(3, [AdoMet_dc, Amidinotransf, Arginase,
                     OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     protocluster    1701..31189
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[36678:46167]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      11701..21189
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
     CDS             complement(1706..3550)
                     /locus_tag="ctg16_26"
                     /transl_table=11
                     /translation="LYMKMKREDVRNIAIIAHVDHGKTTLVDELLKQSGVFRENQEVQE
                     RVMDSNDIERERGITILSKNTAITYKGTKINVIDTPGHADFGGEVERVLKMVNGVVLVV
                     DAFEGVMPQTKFVLMKALELSLPVIVCLNKVDRPEARPNEVVDEVLELFMDLDASEEQL
                     DCPFLFASARDGYAVRELDDLVNNKKDMTPLFDTILDYIPAPEGDPDANTQVLISTIDY
                     NEYVGRIGIGKVDNGCLKVNQEAVVVNHHEPDKQKRVRISKLYEFDGLNKVDVTEAKIG
                     SIVAISGIADIHIGDTICAPENPVAIPFQKISEPTLSMNFIVNDSPLAGQEGKFVTSRH
                     LRDRLFRELNTDVSLRVEETDSPDSYKVSGRGELHLSVLIENMRREGYEFAVSKAEVLY
                     HTDENGKKLEPMELAYVDVPDEFTGAVIEKLSQRKGEMLNMKPITGGYTRLEFNIPSRG
                     LIGYRGEFMTDTKGNGIINTIFNGYAPYKGEIAYRKLGSLIAFETGESVTYGLFSAQDR
                     GTLFIGPGEKVYAGMVIGSSSRAEDIELNVCKKKHLTNTRSSSADEALTLVPPKILSLE
                     QALDFIDVDELLEVTPESLRIRKRILDPTLRKRAGMKK"
     CDS             3801..4430
                     /locus_tag="ctg16_27"
                     /transl_table=11
                     /translation="MADKIFENNQVSIMGEIVSDFRFSHEVYGEGFYMVDVAVNRLSNY
                     LDYIPLMISERLIDVNADYIGQIIYVNGQFRSFNRHEEKKNRLVLSVFVRELEFLEELQ
                     EDMKSNQIFLDGYICKEPIYRKTPLGREIADLLIAVNRSYGKSDYIPCICWGRNARFAS
                     GFEVGGHVQVWGRIQSREYVKKISELETEKRVAYEVSVSKVDFLEE"
     CDS             4814..5704
                     /locus_tag="ctg16_28"
                     /transl_table=11
                     /translation="MAIFKGAGVAIVTPMKENEEVNYDKLEELVEWQIEQGTDAIVIVG
                     TTGESSTLTTEEHSDVIRAAVRFAKHRVPVIAGTGSNCTREAIHLSEEAEKAGADGLLA
                     VTPYYNKATQGGLIRYYTEIAEAVKLPIIMYNVPGRTGCNIMPETAATLFKNVENIVGI
                     KEATGSLAQASKLMYLTDGKIDLYSGEDGIVVPLMAIGAIGVISVWSNVAPADVHDMCA
                     AFSAGDLLRARELQLKAQPLVDALFSEVNPIPVKKALNLMGLEVGPLRSPLTEMTPENA
                     AKLAEAMKNYGIKLA"
     CDS             5824..6600
                     /locus_tag="ctg16_29"
                     /transl_table=11
                     /translation="MIKAIMNGCNGKMGQVISAICKEDPQIEIVAGVDLYDGIKNDYPV
                     FPNISVCDVKADVIIDFSNAKAVDDLLVYSVDKKIPVVLCTTGLSEEQMEQVKAASGQV
                     AVLKSANMSLGINLLMQLLAQAATILAPAGFDMEIVEKHHNQKLDAPSGTALALADSMN
                     DALGHVYEYKYDRSSERKKRDPHEIGISAVRGGSIVGEHEVIFAGLDEVIEFKHTAYSR
                     SVFGKGAVEAAKFLAGKEAGFYDMQDVIRATMEQAD"
     CDS             6652..6825
                     /locus_tag="ctg16_30"
                     /transl_table=11
                     /translation="MGTGAWKRFLFPFLYRAENEQNLVSSARICYYLRGIFDFDILRGN
                     IWKNIWKQICGI"
     CDS             6789..8753
                     /locus_tag="ctg16_31"
                     /transl_table=11
                     /translation="MEKYMETDLRYLKSLANQYPTVAAAATEIINLQAILSLPKGTEHF
                     ITDIHGEYDQFQHVIRNGSGAIKRKIEEEFGNAISAGEKKAIATLIYYPEQKLEQVLKT
                     EENMEDWYKVSLYRLIRICKSASSKYTRSKVRKALPKDFAYVIEELLTGRPDVSDQEAY
                     YNEIIRSVIRTGRAPELVIAFCNLIRRLVVDHLHVVGDIFDRGPYPNLIMDTLMQHHSV
                     DIQWGNHDIYWMGAAAGSRPCICNAIRISAKYGNLNLLEDGYGINLVPLARLAMSRYDK
                     DPCTCFKLDYREDEYDVRDAMLDEKMHKAITVIQFKLEGQMIMRHPEFGMDERLLLDKI
                     NIEKGTVCVEGKEYPMKDLNFPTIDWKHPYELSSEEEDVMERITQAFLNCEKLQRHVRF
                     LFTQGSLYKVYNGNLLYHGCVPMNEDGTFTRVNVYGKEYSGKALYDVLENYARKGYYAI
                     DPGEKKKGLDILWFIWENQNSPVFGKAKMTTFERYFIADKATHQEPKNPYYRLLEEEEV
                     VNRILSEFGLEGAEAHIINGHIPVEAKRGESPVKCGGKLLIIDGGFSKAYQPKTGIAGY
                     TLIYNSYGLVLAAHEPFESVEKAVQEGSDIASHTILVQHVVRRKLVADTDIGRELRASI
                     RDLEALLQAYRDGILVEKI"
     CDS             8783..9610
                     /locus_tag="ctg16_32"
                     /transl_table=11
                     /translation="MYIGNHLSASKGYAAMGRMAVKLGANTFAFFTRNPRGGAAKAIDP
                     ADVEKLLELMREQQFGKLVAHAPYTMNLCAAKEDIRKFSKEMIADDLRRMEYTPGNYYN
                     FHPGSHVGQGADAGIEWIAEALNEVLTPEQTTTVLLETMAGKGSEVGRSFEELRAIIDR
                     VELSDKLGICLDTCHVWDAGYDIAGDLDGVLEKFDHVIGLNRLCAVHFNDSMNDRGSHK
                     DRHACIGEGKIGLDAMRRVATHPLLSDKPFILETPNDDEGYRREIALFREWRE"
     CDS             10001..11629
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: OKR_DC_1_7_arginine"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_33"
                     /sec_met_domain="OKR_DC_1_C (E-value: 6.2e-11, bitscore:
                     34.7, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 4.9e-130,
                     bitscore: 425.6, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCAQHTGICLFCVNRKLRPYYIKTFRGDAYLAVRYIMLCIPHQGA
                     SKQNVRRIMEAGSQKRAPVYEALEQLKKRRVVPFDVPGHKRGRGNPELVELLGEKCVSL
                     DVNSMKPLDNLCHPVSVIKEAEELAAEAFRADHAFFMVGGTTSSVQSMVLSVCRAGDKI
                     ILPRNVHKSVINALVLCGAIPVYVNPEVDKKLGISLGMEISEVERAILENPGAVAVLVN
                     NPTYYGICSDLRSIVKLAHEHEMLVLVDEAHGTHLYFGEDLPVCAMDAGADMASVSMHK
                     SGGSLTQSSLLLTGKNVNWEYVSQIINLTQTTSASYLLMSSLDISRRNLALRGRESFRK
                     VAEMAEYARAEINDIGGYYAYGKDMVNGGSVYDFDVTKLSVYTRGIGLAGIEVYDLLRD
                     EYDIQIELGDIANILAYISIGDRIQDIERLVGALADVKRLYSKDPAQMLNTEYINPTVL
                     VSPQAAFYAEKKCMPIRETAGKICGEFVMCYPPGIPILAPGEMITPEIIEYIIYAKEKG
                     CSMQGTEDPAVEHLNVLVDDRQVWK"
     CDS             11701..12594
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_34"
                     /sec_met_domain="Spermine_synth (E-value: 2.7e-53,
                     bitscore: 172.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 6.4e-14,
                     bitscore: 43.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VEYGLGKVEESVELWFSDNQTDHVKVSVKVEKQLFGEQTDFQRID
                     VFESREFGRFLSSDGSIVFSEKDEFIYDEMIVHVPMAVHPHVKKVLVIGGGDGGVAREL
                     SYYEEIEQIDVVESDRTFVDVCRKFFPDNACGLEDPRVNIYYEDGLRFLRTKHDAYDLI
                     INDAIDPLGHTAGLFTKEFYGNCYRALKEDGIMVYQHGSPFYDEDEESCRVMHRKASHS
                     FPISRVYQAHIPTCSSGYWLFGFASKKYHPLTDLNVERWKARGIKTWYYTTNLHKGAFM
                     LPKYVEDMLEEEEGRK"
     CDS             12728..13987
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_35"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.5e-43, bitscore:
                     141.8, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.3e-33,
                     bitscore: 108.0, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRLLIIGCGGVAGVAIHKCCQNSRTFSEICIASRTKEKCDALKE
                     KLQGTTDTVITTAKVDADNVDELIALIRDYKPDAVLNVALPYQDLTIMDACLACKVDYI
                     DTANYEPEDTDDPAWRAIYEKRCKEAGFTAYFDYSWQWAYQKRFADAGITALLGSGFDP
                     GVTSVFTAYALKHYFDEIEYIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETKPMEIKREYNFPQVGEKDMYLLHHEEIESLAKNVPGVKRIRFFMTFGQSYLTHMQ
                     CLEDVGMLSTSPIQYEGREIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGKKDGKEK
                     TIYIYNVCDHQECYREVGSQAISYTTGVPAMIGAALVVDKVWDKDGVFNIEEFDPDPFM
                     DMLNQYGLPWVVDENPKTVA"
     CDS             14027..15223
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_36"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.3e-14,
                     bitscore: 46.3, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKWNELPTPCYVVDQKKLKENLIILHNLEQDTGCHVLLAQKAFST
                     YALYPLIGQYISGTTASGLYEARLGAEEMGRENHVFAPAYKDSDMEELVTLCDHVIFNS
                     FAQYVRHRKKVAAQNVASGTEHRVSIGLRINPEYSTQEGHAIYDPCAPGSRLGMTREAF
                     EKGLAGLGMRRQEDGSYELPEDVEGLHFHTLCEQDADDLERTFLAFEEQFASYLKQVRW
                     LNLGGGHHITRPGYQIERLKKLIGYIRETYGLAVYLEPGEAVALNAGYLVTEVCDIVHN
                     GMDILILDASAACHMPDVLEMPYRPPLRDSFPAGEQKYTYRLSSLTCLAGDVIGDYSFT
                     HEIQIGDRLVFEDMAIYSMVKNNTFNGIPLPSIAMLREDGEVEMIKQFGYEDFKGRLS"
     CDS             15280..16503
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: PAD_porph"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_37"
                     /sec_met_domain="PAD_porph (E-value: 5.1e-117, bitscore:
                     382.6, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKMQKCAEDPKERMTTPQTDGFFMPGEYEPHDGCILIWPSRPG
                     SWIYGARDARIAFRDVIAAIAQSENVYVAAGRDAIDSAREMLTGEDAPWKKRVTVFELE
                     TDDAWARDVAPTFVKDGAGRVRAVNWSFNAWGGSVDGLYASWALDDAFAKAFAAKYGYA
                     CYDAAPFVLEGGSIHSDGEGTLLVTEACLLSAGRNPGLTREEIEEKLRTYLGIKKVLWL
                     PRGIYQDETNEHVDNVCAFLRPGEVVLAWTDDETDPQYPLSQQTLAYLEGETDARGRKL
                     VIHKLPIPDHPVCITEEELAGYSFAEGEDEREAGERLAASYVNFYFSNEAVVLPAFGGE
                     NEESDRRAAALLAQWNPGRKIIPVQARAILVGGGNIHCITQQIPAAKMQQQKCSSGKVD
                     RDKKRKRV"
     CDS             16500..17378
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_38"
                     /sec_met_domain="CN_hydrolase (E-value: 4.3e-55, bitscore:
                     178.7, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRVKVAAIQMRCAASVEENLKKAEAMVRKAAAEGANVILLPELF
                     EREYFCQQRRYDFYHYAKPVMENDAVRMGMRLAAELGVVLPISFYERDVNNLYNSIACI
                     DADGTVLGVYRKTHIPDDHYYQEKFYFTPGDTGFQVFSTRYGRIGVGICWDQWFPESAR
                     CMALAGAELLFYPTAIGSEPILECDSMPHWRRCMQGHAAANLMPVVAANRIGEETVEPC
                     EENGGQRSALVFYGSSFLTDETGEILAEAGRDEEEILVQEYDLDELDARRLEWGLFRDR
                     RPECYGIISGR"
     CDS             17466..17939
                     /locus_tag="ctg16_39"
                     /transl_table=11
                     /translation="MKDREELLKEIALMLERQDMLSKLTENQCLDEYGYSETHCIDYIG
                     RLELPNVTKVAEHMGMTRGAISKMTKKLLAKGLIEKYTLETNKKEVYFKLTDQGRLLFD
                     EHAKRHKRWEKRDMEFLARYSVEDVRTVSRFMTEFNGYLEEQIETITGTQAEG"
     CDS             complement(18031..18732)
                     /locus_tag="ctg16_40"
                     /transl_table=11
                     /translation="MSITILNYHDQAFVDQINTEAAARAEAERAAAEAAKAQAAGSDFS
                     SVLTNATDAYSGSTACSEDLSAIFDEAANTYGVSSTLLKSIARAESNFNTSAVSSAGAV
                     GIMQLMPATAASLGVTDSYDAYQNIMGGANLISQLLARYNGDTSLALAAYNAGSANVDK
                     YGGIPPFSETQNYVQKVLSYMGSDTNTVASASTAETSEDVATTVSNFIAANNISQDTVE
                     KLLTLLEVLNA"
     CDS             18815..19570
                     /locus_tag="ctg16_41"
                     /transl_table=11
                     /translation="MKTKQAEQKGTYLRAFRAAFPYTVPVLTGYLFIGMAFGVMIQEKG
                     YNFLWAMLMSLVIYAGSGQYLAVNFFAPGVSLFNVIFMEFMVNIRHIFYGLSLLERFSE
                     MGKKRLYMIFSLTDETYSLFFVTKVPKDVKEEQFLFAIAVLDQSYWIIGSGIGALLGNV
                     LPFSAEGIDFAMTALFVVIMVEQWMEKQNRPSVVIGLVCGLVCRLVFGADNFILPTMIC
                     VMVILLSCKKIFDKMIPEDGKEGGEPECQ"
     CDS             19561..19893
                     /locus_tag="ctg16_42"
                     /transl_table=11
                     /translation="VPVSVGRSLAIIFTVAGTIFFTRLIPFLFFPKGKEIPPIIRYLGR
                     VLPPAVIGMLVIYCLKNVSVLAVPFGLPEFIAVAAVIVLHVWKRNNLLSIGVGTALYMF
                     LIQVVF"
     CDS             19912..21189
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: Orn_Arg_deC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_43"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 2.5e-28, bitscore:
                     91.0, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 3.8e-21,
                     bitscore: 67.2, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKPFVTKEQLEEIVKKYPTPFHLYDEKGIRENAKAVKEAFAWN
                     PGFREYFAVKATPNPFILDILKEYDCGCDCASLTELMLADSQGFDGKHIMFSSNDTPAE
                     EFAFANELGAIINLDDFTHIDFLEKTIGRIPETISCRYNPGGVFKMSNGIMDNPGDAKY
                     GFTHEQIIEGFKILKEKGAKHFGVHAFLASNTVTNEYYPKLARELFELVVELRDKTGCD
                     IRFINLSGGVGIPYTPDQTPNDIRVIGEGVRVAYEEILVPAGLGDVAIYTEMGRFMLGP
                     YGCLVTTAIHEKHTHKEYIGVDACAVNLMRPAIYGAYHHITVMGKEDAPCDHKYDVTGS
                     LCENCDKFAIDRMLPKIDMGDLLVIHDTGAHGFSMGYNYNGKLKSAEVLLKEDGSTQLI
                     RRAETPEDYFRTFDCFDILKDMKHPK"
     CDS             21233..21982
                     /locus_tag="ctg16_44"
                     /transl_table=11
                     /translation="MCIDTERFERARGRVIGIERQRLGIGTLSEKTVHAVLKNYYAPDE
                     DMHEIPIENFVADIFDGEAVIEIQTRSFQNMRRKLAAFLPLYPVTIVYPIPHVKWLHWM
                     DEETGEISPGRKSPKKGNAYQAFIELYKIRPFLKDPNLRLRLDLIDMEEYRLLNGWSRD
                     KKKGSDRFDRIPLTFVEEVRVDRREDYMQFIPYEIPEEFTAKDFAACAKIPVRLAQTVL
                     LILTDLLIVERIGKQGRSYLYRICEIE"
     CDS             22083..23645
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 62.5; E-value: 1.4e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_45"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.4e-19, bitscore:
                     62.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNTAIKLSGILLAGAVFFSTLLGYGTQAAAATAIGSDTEAGQAS
                     GDGSVASVADLPGKHIGVQLGTTGDIMVSDYETDGSGTVVERYNKGADAVQALKQGKLD
                     CVIIDELPALAFVEQNEGLKILEENFVEEDYAFVIAKGNEALVDQVNETLRELKDEGVL
                     DNIAKNYTGTDEEIGKYPYEILDVERTNGTLTVGTNAEFPPYEYYEEGKITGIDMDIMQ
                     AVCDKLGMELKIEDMAFDSVIPAVSTGKVDIGALGFTVTEERKKNVNFTDTYAKSKQVI
                     IVRDTSVTAEKTGIGEKFYDNFIKDSRYTYLLKGLLNTLIITVFAVMIGIVFGFLIAIV
                     RTNHDRNGGLTILNALCKAYLAVVRGTPVMIQLLIIYYVIFQSINTGKLFVAVIAFGLN
                     SAAYVAEIVRSGIMAVDIGQFEAGRSLGLNYKQTMLSIILPQAVKNILPALCNEFISLL
                     KETSISGYIGLMDLTKGGDIIRSVTYEAFMPLIAVAAIYFLIVMGLSKAVGLLERRLRS
                     NER"
     CDS             23635..24375
                     /locus_tag="ctg16_46"
                     /transl_table=11
                     /translation="MSDNTVILEVKELHKSFDGHEVLKGISTTIKKGDVLALIGPSGCG
                     KSTFLRSLNLLEIPTAGHVLFEGTDLTDPSVDINHVREKIGMVFQQFNLFPNMTILENI
                     MLAPVKLGKMTKEEANTRAMELLKRIGLADKAGAYPAQLSGGQKQRIAIVRSLAMDPDI
                     ILFDEPTSALDPEMVGEVLAVMQELAEDGMTMVVVTHEMGFAREVANRVMFINDGVIQE
                     EGTPQEIFGNPKSQRLQEFLSKVL"
     CDS             24584..25570
                     /locus_tag="ctg16_47"
                     /transl_table=11
                     /translation="MKWNKYTIETTTAAEDYMSAMLADLGIEGVEIEDNIPLSKEDQAD
                     MFIDFLPELPPDDGVSHVSFYLEDDGEDRTELLKQVKEALEDLRKVVDVGSGVITSDQT
                     EDLDWINNWKKFFSSFYIDDILIKPTWEELKPEDADKFLIEIDPGVSFGTGKHETTQLC
                     IRQLLKYIRGNDAYTPEKRAPKVLDVGCGSGILSIVALKLGASAVVGTDLDPDCMTSTH
                     ENMAVNHLDAALGTFYVGNLIDDAALQEKVGTEEYDIVVANILADVIIPMAPVIPARLK
                     RGGYFITSGIIDFKENAVKEAIEAAGLTVVEINHQGEWVNITARKPE"
     CDS             25638..26408
                     /locus_tag="ctg16_48"
                     /transl_table=11
                     /translation="MYQFFVEDEQIANDLVTIEGSDVNHIRNVLRMKCGEKVRISSTSG
                     RNFFGTIDRIAENVVEVCITEETALDTELSCRICLFQGLPKSDKMELIVQKAVELGAAE
                     VIPVAMKNCVVKLDAKKAAAKAARWQEIAKSAAKQSKRSRIPVVREPVNYREAVALAGE
                     LDVVLLPYENERGMAATREVMERIAPGQSVGIFIGPEGGFDPSEIALAKEEGMHLVSLG
                     KRILRTETAGLATLSILMYHIESVSEAEEERDQP"
     CDS             26463..27605
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_49"
                     /sec_met_domain="Aminotran_5 (E-value: 2e-81, bitscore:
                     265.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LDNSATTRCSERAKNKMVQILTEDYGNPSSLHNMGKTAEDYIKEA
                     KEQIARTLRCDEKEIVFTSGGTESNNMALIGGALANKRQGKHIITTSIEHASVQAPLAY
                     LKELGYEITELSVDHDGIISLEELRDAVREDTVLVSIMMVNNEIGAVEPVEEAAKVIKA
                     KNPDTLFHVDAIQAYGKFRICPKKMGIDLLSVSGHKIHAPKGTGFLYIRDKVKVKPIIY
                     GGGQQKGMRSGTENVPGVAALGEAAAEIYENFDAKVDHMYEIKQRFIDEVTQIPGVTVN
                     GKTGRDSAPQIVSITIEDVRSEVMLHSLEEYGIYVSAGSACSSNKPAPSRTLQGIGLPK
                     QKLESTIRISFCVNTTEEEVDYAVEKMKEIIPFRRKFTRK"
     CDS             27617..28801
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:Thiamine biosynthesis protein (Score: 216.9;
                     E-value: 6.4e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_50"
                     /sec_met_domain="ThiI (E-value: 6.2e-67, bitscore: 216.9,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYKAFLIKYAEIAIKGKNRYLFEDALVSQMNHALKKVDGTFHIR
                     KEQGRIYVEMEGEYDYDGAVEALQHVFGIVGICPVVLLEDEGFDVLAGEVIRYIDEVYP
                     DKHFTFKVNARRARKNYPLESMEINAQMGERILEAFPETRVDVHKPQVMFNIEIRNQIN
                     VYSTVIPGPGGMPVGTNGKAMLLLSGGIDSPVAGYMIAKRGVTIDATYFHAPPYTSERA
                     KQKVVDLAKIISKYTGPINLHVVNFTDIQLYIYEQCPHEELTIIMRRYMMKLAEHFAKE
                     SKCLGLITGESIGQVASQTMQSLAATNEVCTMPVYRPLIGFDKQEIVEISEKIDAYETS
                     ILPYEDCCTIFVAKHPVTKPSLNVIHNDERKLSEKIDALMQEAIDTVEVIHIEA"
     CDS             complement(28908..29138)
                     /locus_tag="ctg16_51"
                     /transl_table=11
                     /translation="MKTVQISLNSIDKVKSFVNAITQYEYDFDLISGRYVIDAKSIMGI
                     FSLDLSKPIDLAIHAENNMDEIMETLKPYLI"
     CDS             29276..30580
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_52"
                     /sec_met_domain="Radical_SAM (E-value: 2.9e-26, bitscore:
                     84.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAALHNLGCKVNAYETEAMQQILEEAGYEIVPFSEYADVYVINT
                     CSVTNMADRKSRQMLHRAKKQNPDAIVVGAGCYVQTKEAQALVDESIDIVIGNNKKHEL
                     VPLLREYEASHRKMACVADINHEKQAYEELSLSRTAEHTRAFIKVQDGCNQFCTYCIIP
                     FARGRVRSRELPDVLQEIRTLAKSGYREVVLTGIHLSSYGVDNGESLLHLIEAVHELEG
                     IERIRLGSLEPRIVTDAFAKRLSELPKICPHFHLSLQSGCDTVLSRMNRRYDTAEYEVG
                     CALLRRYFEHPAITTDVIVGFPGETDEEFWTTERYLERIHFYEMHIFQYSRREGTKAAA
                     MPDQVPEAVKKERSEKLLALGHRMSGEFRRYYLGRQVTALLEEEFLYDGKRYYTGYTKE
                     YVKVAVETKKDLSNTFVTGTLKTQLTEDVYLLVEF"
     CDS             30683..30946
                     /locus_tag="ctg16_53"
                     /transl_table=11
                     /translation="MQEINNTQYFKVEKGPELRVSDVLAIVYRALMEKGYNPVNQIVGY
                     IMSGDPTYITSHNNARSLIMKVERDELVEEMLKAYIRNNNWE"
ORIGIN
        1 aaaagggtgt cggatttttt tcgctattgc acttcttatc tgtgtgggag gcattccggc
       61 atatgcagaa gaaccggtac cggacgcagg ggaaatcacc ggcagggtat tatttatcag
      121 ttcctattcc tatgcatggg agacggttcc ggaacagatt cgcggtataa aagaagcatt
      181 gggcgctggt gtacagctgg attatcagtt tatggatacc aaaaatgtcg agacggcgga
      241 gagtgaacag ctattttacc agacgctaac atactatctg aagatggttc cggcgtatga
      301 tgttgtgatt gtaggagacg atgcggcgtt tcagtttgca atgacgtatc gggatgagct
      361 gtttgcgcag acgccggttg tttttgaggg agtcaatgac ggggaactgg cgaagaaggc
      421 ggcagcagac ccgcttgtga cgggcgtggt tgagacgctc tcttatgaga atacgatcac
      481 gctggcaaag aagctgtatc cggatgcaag acaggtggta ggaatactgg atgatacggt
      541 gaccggagag ggcgaacgca aggaattcca gtattacgat actgtttttc cagagttgga
      601 ctttgtagag atcgacgctt caaagctctc ccaggaagaa ttaaaaagac aggttgctgc
      661 gctgggggag gagagcattc tggtctatat tatgtgcagc agggatggcg acgggaatgt
      721 gtacgcggcg gcggaagcga tccagatgct gagtgatgtg gcgcagattc cgatgttttc
      781 aattgtctcg cacggtatgg gaaaaggatt tttaggcggc gagattgtct cgcaggaaca
      841 gatgggaaaa agggcaggag aaatggcggt gcagatactg gagggcacgg attgtgcagg
      901 gatctccatt gtgatggagc cgccgaaggt atattgcttt gatgaaaatg tgatgcgcag
      961 gtttggaatc agtgcatcaa agcttcccgg ggatgcagtc atcatcaatc acagggagac
     1021 cttctgggaa aagaaccggg atacgatcag ggcaacgctg gtgattgctg ccgtggcgtt
     1081 ggcaatggtg gcatggctgg cggtggacaa tatgcgccga cgcaaaatga acgaagtgat
     1141 taccagggca aacgaaaaac tgtcttacag tgcacattat gatgtactga cacaccttaa
     1201 gaaccgtagt gtctttatgg aagatatcag gcagcggatt gtctccgggg aagaatttac
     1261 ggtttttatg tatgatctgg ataattttaa gcgggtgaac gacacctacg gacacaatac
     1321 aggggacgag gtgctgcgcg aagtggcact tcggtcgctg gcggtggagg atggccattt
     1381 cacaccgtac cgcctggcag gagatgagtt tgtagcactg atcgactgcg gcgattacag
     1441 ggtcatagag cgatatgcat ctggtttgat ggaacgtctg caaaagccgt gcagaatggg
     1501 agaggaggac gagacactgg gagtcagtct cggaatcgcg gtgtggccgg aacacggagc
     1561 ggatgcaacg gaacttctgg cagcggcgga tgctgcaatg tatacagtga agaaaaacgg
     1621 aaaaaatgga tatgcatttt ataaggagcc atgtgcacca taggaaacgg tgcacatggc
     1681 tcctttttaa gagtagaaat acgacttatt ttttcatgcc ggcgcgtttt cttaaggttg
     1741 gatcaagaat acgcttgcgg atacgaagac tctccggtgt aacctccagg agctcgtcga
     1801 catcgatgaa atcgagtgcc tgctccagac ttaaaatctt aggcggaacc agagtcagtg
     1861 cctcgtccgc agaagaggaa cgcgtgttgg tcaggtgctt tttcttgcag acattcaatt
     1921 cgatatcctc ggctctggaa gatgaaccaa tgaccatgcc ggcgtatacc ttttcgccag
     1981 gtccaataaa gagcgtaccg cgatcctgtg cggaaaacag accgtaggtt acggactcac
     2041 cggtctcaaa tgcgatcagg gaaccgagct tgcggtaagc gatctcgccc ttgtacggtg
     2101 catagccgtt gaaaatggtg ttgatgatac cgttaccctt ggtatccgtc ataaattcac
     2161 cacggtaacc gatcaggccg cgggacggga tgttgaactc cagacgtgtg taaccgccgg
     2221 taatcggttt catgttcagc atttcgccct tgcgctggct taacttttcg atgacggcac
     2281 cggtaaattc atccggtaca tcgacataag caagctccat cggctctaac ttcttgccgt
     2341 tctcatccgt gtggtagaga acttcagctt tgctgacggc aaactcataa ccctcgcggc
     2401 gcatgttctc aatcagtacg gacagatgaa gctcaccgcg gccggatact ttgtaggaat
     2461 ccgggctgtc cgtttcctcg acacgcagag aaacatcggt gtttaattcg cggaacagac
     2521 ggtctcttaa atgacgggag gtaacgaatt taccctcctg tccggcgagc gggctgtcat
     2581 ttacgatgaa attcatggac agtgtcggct cggaaatttt ctggaacgga atggcaaccg
     2641 gattctcagg tgcgcagatg gtatcaccga tatggatatc tgcaataccg gaaatagcta
     2701 cgatggaacc gatctttgcc tctgtgacat ccaccttgtt cagaccgtca aactcgtaaa
     2761 gcttgctgat gcggacgcgt ttctgcttgt caggctcgtg gtggttgaca acaaccgcct
     2821 cctgattgac ttttaagcag ccgttgtcga cctttccgat accgatacgt ccgacatatt
     2881 cgttgtaatc gatggtgctg atcaatacct gggtgttggc gtccggatcg ccctccggtg
     2941 cagggatata gtcaaggatc gtgtcgaaca gcggagtcat atcctttttg ttgttcacca
     3001 gatcgtcaag ctcgcggact gcgtagccgt ctcttgcaga agcaaaaagg aacgggcagt
     3061 caagctgctc ctcggaagcg tccagatcca tgaaaagctc aagcacttcg tccacaacct
     3121 cgttcggacg tgcctccgga cggtcgactt tgttgagaca cacgataacc ggaagagaaa
     3181 gctcgagcgc tttcatcaga acgaacttgg tctgcggcat aacgccctcg aaagcgtcaa
     3241 cgaccagcac aacgccgttt accatcttaa ggacacgctc aacctcgccg ccgaaatcag
     3301 cgtggccagg ggtgtcgatg acgttgatct tagttccttt ataagtaatc gctgtatttt
     3361 tggaaagaat cgtgatacca cgctctctct caatatcatt agagtccatg acacgctcct
     3421 gaacctcctg gttctcacgg aacacgccgc tctgttttaa caattcatcg accagagtgg
     3481 tcttgccgtg atcgacatgg gcgataattg caatgttacg gacatcttca cgtttcattt
     3541 tcatatacaa aatctctctt tcctgtgtga aacctagtct aaaaaagtaa ccaatctatt
     3601 ttatcatatt ttcggagatg cgcaagtggt acttgcgaca aaatccgcca tttcattccc
     3661 tttgttatcg acatgttgca tgaaaattct ggcaccggac gtgataaaaa taatgtgtca
     3721 ggcagatcat accagcagaa cggaacgaaa aagaagaaca acgcaaaaaa gagtatggtc
     3781 gtaagaaggg agaaagattc atggcagata aaatttttga aaacaaccag gtgtcaatta
     3841 tgggagagat tgtatctgat ttccggttca gtcacgaagt gtacggagag ggattttata
     3901 tggtggatgt ggcagtgaac cgcctgagca attatctgga ttacattccg ctaatgatat
     3961 ccgaacggtt gattgacgta aatgcagatt acataggaca gatcatttat gtgaacgggc
     4021 agttccgttc gtttaaccgg catgaggaga aaaagaaccg ccttgtctta tcggtgttcg
     4081 tgcgggaact ggagtttttg gaggaactgc aggaggatat gaagagcaac cagatttttc
     4141 tggacggata tatctgcaag gaaccgattt accggaagac gccgctggga cgggagattg
     4201 cggatcttct gatcgccgtc aaccgttcct acggaaaatc agactatatt ccatgcatct
     4261 gctggggcag aaacgcccgg tttgcctctg gctttgaggt gggaggccat gtgcaggtat
     4321 ggggcagaat ccagagccgg gaatacgtca aaaagatctc ggaacttgag acggaaaaac
     4381 gggtggctta cgaggtctcc gtcagcaagg tggatttcct ggaggaataa tcaaaagttc
     4441 cattattgac aaccgttgtt gatagtgcta tgttaatttt aactatatga tacatatttt
     4501 gatagaggtt gcgtgcttta agagtagctt cccggatgtg acaggcacag gggaagggaa
     4561 gcaaaaggaa agcatgccga aagagcaagg cacctgctgc cctggttctt gggcataaag
     4621 ctaagaactt tatgactgtc atctttgcag atggggcgct atcggttctg tataatggca
     4681 tgcagatatg cggcagaaga atcagaccgg ctcaccgagc cggctttttt ttactttttg
     4741 ttctgactct gatctgacag gggcaaaatt gtaccatggg catatattaa cataggagaa
     4801 acggaggatt gacatggcga tattcaaggg cgctggtgta gcgattgtta cacccatgaa
     4861 ggaaaatgaa gaggtaaatt acgacaagct ggaggaactg gtcgaatggc agattgagca
     4921 gggaacggat gcgattgtga ttgtgggaac gaccggagag agttcgacgc tcactacgga
     4981 ggagcattcc gacgtgatcc gggcggcagt gcgtttcgca aagcatcgcg ttccggtcat
     5041 tgccggcacc ggttccaact gcaccagaga ggcgattcac ctttccgaag aggcggaaaa
     5101 ggcaggagca gacggacttt tggctgtgac cccgtactac aacaaagcga cacagggcgg
     5161 attgatccgt tactatacag agattgccga ggcggtaaag cttccgatta tcatgtacaa
     5221 cgttcctgga cgtaccggct gcaatattat gccggagacc gcagccacac tctttaagaa
     5281 cgtggagaac attgtgggta tcaaggaggc gaccggtagt ctggctcagg catccaagct
     5341 gatgtactta acggacggca agattgattt gtattccggc gaggacggca tcgtggtgcc
     5401 tctgatggca atcggtgcga tcggtgtgat ttccgtgtgg tcgaatgtgg cgccggcgga
     5461 tgtgcacgat atgtgcgcgg ctttctccgc gggggatctt ttgcgcgcga gagaactgca
     5521 gttaaaggca cagccgcttg tggatgcgct gttttccgag gtaaacccga ttccggtgaa
     5581 gaaagcattg aatctgatgg gactggaagt gggaccgctt cgttccccgc tcacggagat
     5641 gacaccggag aatgccgcga agcttgcaga agcgatgaaa aattacggaa taaagttagc
     5701 ataaaagaac agatgactcc ggcggaaggg agccgtaagg ccatccgccg gagtatgtgt
     5761 ctgcaccgcc ggctgcatgc ggcacgcgga gcgggcagta cagagaagag aggataacgt
     5821 acgatgatta aggcaatcat gaatggatgc aatggtaaaa tgggacaggt catctccgca
     5881 atctgcaagg aggatccgca gattgagatc gtggcgggag tggatctcta tgacgggatc
     5941 aaaaatgact atccggtatt cccgaatatt tccgtctgcg atgtgaaggc ggatgtcatc
     6001 atcgattttt ccaatgcgaa ggccgtggac gatcttctgg tctatagtgt ggataaaaag
     6061 attccagtgg ttctgtgcac gacgggattg tcggaggaac agatggagca ggtaaaggcg
     6121 gcatcggggc aggtagcagt attaaagtcc gcgaatatgt cgctgggaat caatctgctg
     6181 atgcagcttt tagcgcaggc ggcaacgatt cttgcgccgg caggatttga catggagatc
     6241 gtggagaagc atcacaacca gaagctggat gcaccgagcg gcacagcgct ggcgctggcg
     6301 gactccatga atgatgcgct gggacatgtc tatgaataca aatatgacag aagcagcgag
     6361 cgcaaaaaga gagatccgca cgagatcgga atctcggcag tgcgcggagg cagcatcgtc
     6421 ggggagcatg aggtcatctt cgcgggactc gacgaggtca ttgagttcaa gcataccgca
     6481 tattcccgca gcgtctttgg aaaaggggct gtggaggcgg caaagttcct cgccgggaaa
     6541 gaggcaggat tttatgatat gcaggatgtg atccgggcaa cgatggaaca ggcagactga
     6601 ttggacaggc agacggataa ggcagattga aagcagatac agatggatcg aatgggaaca
     6661 ggagcgtgga aacgttttct gttcccattt ttatacaggg cagaaaacga acaaaatctg
     6721 gtcagcagtg cgcggatatg ttactatttg agaggtatct tcgattttga tattctgagg
     6781 gggaacatat ggaaaaatat atggaaacag atctgcggta tttaaaaagt ctggcaaatc
     6841 agtatccgac cgtggctgcg gcagcgacgg agatcattaa cctgcaggcg attttaagcc
     6901 tgccaaaggg aacagaacat ttcattacag atattcacgg cgagtacgat cagttccagc
     6961 acgtgatccg gaacggttcc ggagcgatta agcgcaagat cgaggaagaa ttcgggaatg
     7021 cgatcagtgc gggagagaag aaagcgattg cgaccctgat ctattatccg gagcagaagc
     7081 tagagcaggt gttaaagaca gaagaaaata tggaggactg gtataaggtc tccctgtacc
     7141 ggctgatccg catctgcaag agcgcttcgt caaaatatac cagatccaag gtgcgaaaag
     7201 cgctgccgaa agattttgcg tatgtgatcg aggaactgct gaccggcaga ccggatgtct
     7261 ccgatcagga agcttattat aatgagatca tccggtctgt gatccgcaca ggccgggcgc
     7321 cggagcttgt gattgcgttc tgcaatctga tccgcaggct tgtggtggat catctgcatg
     7381 tggtgggaga tattttcgac aggggaccgt acccgaatct gattatggat accttgatgc
     7441 agcatcattc cgtggatatt cagtggggga accacgatat atactggatg ggagcggcgg
     7501 cgggaagcag accctgcatc tgcaacgcga tccgtatctc tgccaagtac ggcaatctga
     7561 accttttaga ggacggatac ggcatcaatc tggtgccgct cgccagactt gccatgagca
     7621 gatacgacaa ggatccctgc acctgcttta agctggatta ccgggaggat gagtacgatg
     7681 tgcgtgacgc catgctggat gagaaaatgc acaaggcgat tacggtgatc cagttcaagc
     7741 tggagggaca gatgatcatg cgtcacccgg agttcgggat ggatgagcgg cttttgctgg
     7801 acaagatcaa tatcgaaaaa ggaacggtgt gtgtggaggg gaaggaatac ccgatgaagg
     7861 atctgaactt cccgacgatc gactggaagc atccgtatga actgtcatcg gaggaggagg
     7921 acgtcatgga gcggatcacg caggcgttct tgaactgtga aaaattacag cgtcacgtcc
     7981 gttttctgtt cacacagggc agcctgtaca aggtctacaa cgggaacctg ctctaccacg
     8041 gctgtgtgcc gatgaacgag gacggaacct ttaccagagt aaatgtgtac ggaaaagaat
     8101 attccggcaa ggcgctctac gatgtgctgg agaattacgc gagaaaaggg tactacgcga
     8161 ttgatcccgg ggagaagaaa aaggggctgg atatcttgtg gtttatctgg gaaaaccaga
     8221 attccccggt gttcggaaaa gcaaaaatga cgacgtttga gcgctatttt atcgcggaca
     8281 aggcgacgca tcaggagccg aagaacccgt actaccgcct gttggaggag gaagaggtgg
     8341 tcaaccgcat cctctcggaa ttcgggcttg agggcgcgga ggcacatatc atcaacggtc
     8401 atattccggt ggaggcaaag cggggagagt ccccggtaaa atgcggcggg aagctgctca
     8461 tcattgacgg cggattctcc aaggcctacc agccgaagac ggggattgcg ggatatacgc
     8521 tgatctataa ttcctacggt ctggtgcttg cggcgcacga accgtttgag tcggtcgaaa
     8581 aggcggtgca ggagggaagc gatatcgcgt cgcatacgat tctggtgcag catgtcgtgc
     8641 gtcgtaagct ggtggcggat acggacattg gaagggagct gcgcgcttcg atccgtgatc
     8701 tggaggcgct gctgcaggca taccgggacg gtatcctggt ggagaagatt taaagaaaga
     8761 tagaaggaag caggaaaaga atatgtatat cggaaatcat ctttcggcgt caaagggcta
     8821 tgcggcgatg gggcggatgg cagtgaagct gggagcaaat acatttgcat tttttacaag
     8881 aaatccgaga ggaggtgcgg caaaagcgat tgatccggcg gatgtggaaa agctgctgga
     8941 actgatgcgg gagcagcagt ttggaaaact ggtggcgcat gcaccttaca cgatgaatct
     9001 gtgcgcggcg aaggaggata tccgcaagtt ttctaaggag atgatcgcgg acgatctgcg
     9061 ccggatggag tacacgccgg ggaattacta caattttcac ccgggttccc atgtcggaca
     9121 gggggcggat gccggaatcg aatggattgc ggaggcactt aacgaggtgc tcacgccgga
     9181 gcagacgacg acggttctcc ttgagacgat ggcgggaaaa ggcagtgagg tgggcagaag
     9241 ctttgaggaa ctgcgcgcga ttattgaccg tgtagagctg tccgataagc ttggcatctg
     9301 tctggatacc tgtcatgtct gggatgctgg atatgatatt gcgggagatc tggatggtgt
     9361 cctggagaaa tttgaccatg tgatcggtct gaaccgcctg tgcgcggtac attttaacga
     9421 cagcatgaac gaccgcggtt cgcacaaaga ccgccatgcc tgcatcggcg agggaaagat
     9481 cgggctggat gcgatgcggc gtgtggcgac gcatccgctg ctttcggaca agccgtttat
     9541 tctggagact ccgaatgacg atgagggata ccgcagagag attgcacttt tccgggagtg
     9601 gagggagtag ataagaatcc agagaaatac attgcttttt agaagtgtgt gtgttatact
     9661 tcaaatcaca tgaatgcgaa agctttttca tgcaaatatt tgcccaccaa gagattggtt
     9721 aagcccatac ggacaggcgg ggcagctgcc gatggtggag agatccacgt tattgattga
     9781 gttagaagct caaattttat aagttgatga cgactgcagg cgaaggactg caggaccctg
     9841 aatcgtatgc gatagagata tcacttgtga aacggtcaat aagagtagta atagcaaata
     9901 tttgctggcg aagatgccaa cgtagactct gataatagtt tttgcagcat gtaggacaga
     9961 ttacataaag tatgactatg agaatgtgac aaggcaggtg atgtgtgcgc agcatacagg
    10021 catctgtctt ttttgtgtaa ataggaaact tcgtccctat tacataaaaa cgttccgcgg
    10081 ggatgcgtac ctcgcggtga ggtacataat gctttgcata ccgcatcagg gagcatcaaa
    10141 acagaatgtg aggagaatca tggaagcagg atcccagaag cgcgctccgg tctacgaagc
    10201 gctggaacaa ttaaaaaaga gaagagtcgt tcctttcgat gtgccggggc acaagagagg
    10261 gcgtggcaac ccggagctcg tggaacttct gggggagaaa tgtgtgagtc tggatgtgaa
    10321 ttccatgaag ccgcttgaca atctgtgcca tccggtgtcg gtcatcaaag aggcggagga
    10381 actggcggcg gaggctttcc gtgcagatca cgcgtttttt atggtgggag gaacaacgtc
    10441 ctccgtgcag agcatggtgt tgtcggtctg tcgtgccggg gataagatca tcctgccgcg
    10501 caatgtacat aagagtgtga tcaatgcgct ggtactttgc ggcgctattc cggtctatgt
    10561 gaatccggag gtggacaaaa agcttggcat ttcactcggt atggagatct cggaggtgga
    10621 gcgggcgatt ctggagaatc cgggcgcggt ggcggttctt gtgaacaatc cgacttatta
    10681 cggaatctgt tccgatttgc gctccatcgt gaagctggca catgaacacg agatgcttgt
    10741 gcttgtggat gaagcgcacg gcacccatct gtatttcggg gaggaccttc cggtctgcgc
    10801 gatggatgcc ggtgcggata tggcgtccgt ttccatgcac aaatccggag gaagcttaac
    10861 acagagttct ctgcttttaa ccggcaaaaa tgtcaactgg gagtatgtca gccagattat
    10921 caacctcaca cagacgacaa gcgcgtctta tcttctgatg tcaagtctcg acatctcgcg
    10981 gagaaatctg gcgctgcgcg gaagggaatc gttccgcaaa gtggcagaga tggcggaata
    11041 cgccagggcg gagatcaacg acatcggcgg atattatgct tacggcaagg atatggtgaa
    11101 cggcggaagc gtctatgact ttgatgtgac gaagctctca gtctacacgc ggggaatcgg
    11161 tctggcagga atcgaggtct atgatctgtt gcgggatgag tacgatatcc agattgagct
    11221 gggggacatt gccaacatct tagcctacat ttcaattggc gaccgcatcc aggatatcga
    11281 gcggctggtg ggagcgttgg cagacgtcaa acgcttgtat tccaaggatc ctgcacagat
    11341 gttaaataca gaatatataa atccgaccgt tcttgtttca ccacaggcgg ctttttatgc
    11401 agagaaaaaa tgcatgccga tccgggagac ggcaggaaag atctgcggag agtttgtgat
    11461 gtgctatccg ccgggaattc cgattctcgc gccgggtgag atgattacgc cggagatcat
    11521 cgaatatatc atctatgcca aggagaaggg ctgctccatg cagggaacgg aagatccggc
    11581 ggtggagcac ttaaatgtct tagtggatga ccggcaggtg tggaaataag accgcctgaa
    11641 gaatagctct taaggaagag catacggtca ggaagaaccg gcgtaaggaa gcagcagacc
    11701 gtggaatacg gtctggggaa ggtggaagag agcgtggagt tatggttttc ggataatcag
    11761 accgatcatg tgaaggtgtc ggtcaaagtg gagaagcagc tgttcgggga gcagacggat
    11821 tttcagagga tcgacgtgtt tgaatccagg gaattcggca gatttttaag ctccgacggc
    11881 agcatcgtct tctcagaaaa ggatgagttc atctacgatg agatgattgt gcatgtgccg
    11941 atggcggtgc atccgcatgt gaaaaaagtg ttggtcatcg gtggcggaga cggcggtgtg
    12001 gcgagagaac tttcctatta tgaggagatc gagcagatcg acgtcgtgga atccgaccgg
    12061 acattcgtgg atgtgtgcag gaagtttttc ccggacaacg cctgcggact ggaagatccg
    12121 cgcgtcaata tctattacga ggatggactg cgctttctgc gcacaaagca tgatgcctac
    12181 gatctgatca tcaatgatgc gatcgatccg ctcgggcata cggcgggatt gttcaccaag
    12241 gaattttatg ggaactgtta ccgcgcatta aaagaagacg gcattatggt ctaccagcac
    12301 ggcagtcctt tttatgacga ggatgaggag tcctgccgcg tgatgcaccg caaggcgagt
    12361 cacagtttcc cgatcagccg tgtgtatcag gcgcacattc cgacctgttc ctccgggtac
    12421 tggctgttcg gatttgcgtc aaaaaaatat cacccgctga cggacctgaa tgtggagcgc
    12481 tggaaagcgc gcgggatcaa gacctggtat tatacgacca atcttcataa gggagcgttt
    12541 atgctgccaa aatatgtcga ggatatgctt gaggaagagg aaggcagaaa gtagatggca
    12601 gatgcgggac agaacggact ctgacgggac agtcagcgga gcgttctgtc atccgttggc
    12661 agaatgatat aaataatata aaaatagaaa atacagccgc gggacggcag gaagagagga
    12721 taagtagatg ggaagattat tgattatcgg atgtggcgga gtagcagggg tggcaattca
    12781 caaatgctgc cagaacagca ggactttttc ggagatctgt attgcaagcc gcacaaaaga
    12841 aaaatgtgac gcgttaaagg aaaagctgca gggaacgacg gatacagtga tcacgacagc
    12901 gaaggtggat gcggataatg tggacgaact gatcgcactg atccgtgact acaagccgga
    12961 tgccgtgtta aatgtggcgc tgccttacca ggatctgacg attatggatg cctgcctggc
    13021 atgcaaggtg gactacatcg ataccgcgaa ctacgaaccg gaagataccg acgatccggc
    13081 gtggcgtgca atttatgaga agcgctgcaa ggaggcgggc tttaccgcgt acttcgatta
    13141 ttcctggcag tgggcatatc agaaacgctt tgcggatgcc ggcatcacgg cgcttcttgg
    13201 cagcggcttt gaccctggcg tgacgagcgt gtttaccgcc tatgcgctga agcattattt
    13261 cgatgagatc gagtacatcg atatcttaga ctgcaacggt ggagaccacg gttatccgtt
    13321 cgccaccaat ttcaacccgg agatcaacct ccgcgaggta tccgcaaacg gctcctactg
    13381 ggaggacgga cactgggtag agacaaaacc gatggaaatt aaaagagaat ataatttccc
    13441 gcaggttggc gagaaagaca tgtatctgct tcatcatgag gagatcgagt ctctggcaaa
    13501 gaatgtgccg ggagtcaagc gcatccgctt cttcatgacc ttcggtcaga gctatctgac
    13561 ccatatgcag tgtctggagg atgtcggaat gctctccact tccccgatcc agtatgaggg
    13621 aagagagatc gtgccgatcc agttcttaaa ggcattgctt ccggacccgg cgtcactggg
    13681 tcctagaacc gttggcaaga cgaacatcgg ctgtattttt accggcaaga aggatggcaa
    13741 ggaaaagacg atctatatct acaacgtctg cgatcaccag gagtgctaca gggaggttgg
    13801 ctcacaggcg atctcctaca cgacaggagt tccggcaatg atcggtgcag cgcttgttgt
    13861 agataaggtg tgggataagg acggcgtttt caatatcgag gagtttgatc cggatccgtt
    13921 tatggatatg ctcaaccagt acggactgcc gtgggttgtc gatgagaacc ccaagacggt
    13981 ggcgtagccg ttcgtaaaaa gagccggaca gggagagacg agagcaatga agtggaatga
    14041 acttccgaca ccatgctatg tggtggatca gaaaaaatta aaagagaatt taataatatt
    14101 gcataatctg gagcaggata cgggatgcca tgtcctgctg gcgcagaaag cgttttccac
    14161 atatgcgctc tatccgttga tcggacaata catcagcggt accacagcga gcggactcta
    14221 cgaggcgcgt ctcggcgcag aggagatggg gcgtgagaac catgtgtttg ctccggcgta
    14281 caaggacagt gacatggagg aactggtcac gctctgcgac catgtgattt ttaattcctt
    14341 tgcgcagtat gtcagacaca ggaagaaggt ggcggcgcag aatgtcgcca gtggtacgga
    14401 gcaccgtgtc agcatcggac ttcggatcaa tccggagtat tccacgcagg agggacatgc
    14461 gatctatgat ccctgcgcgc ccggttccag actaggcatg acaagagagg cgtttgagaa
    14521 aggacttgcc ggacttggca tgagacggca ggaggatgga agctatgaac tgccggagga
    14581 tgtggaggga ctccattttc acacgctctg cgagcaggac gcggatgatc tggaacgtac
    14641 gtttttggcg tttgaggagc agtttgcttc ttatttgaaa caggttcggt ggctgaatct
    14701 gggcggagga catcatatca ccagaccggg ttaccagata gagcgtttaa agaagcttat
    14761 cggctatatc agggagacct acggacttgc cgtgtatctg gagcccggcg aggcggttgc
    14821 cttaaatgcg ggatatctgg taacggaagt gtgcgatatt gtacacaacg ggatggatat
    14881 tctgattctg gatgcgtctg cggcgtgtca tatgccggac gttcttgaga tgccgtatcg
    14941 cccaccgcta cgggacagct ttccggcggg agaacagaaa tacacctacc ggctgtcctc
    15001 gctcacctgt ctggcggggg acgtcatcgg ggactacagt ttcacacacg agattcagat
    15061 cggcgaccgt ctggtgtttg aggacatggc aatctactcg atggtgaaga ataatacctt
    15121 taatggaatt ccgcttccgt cgatcgcaat gctccgggaa gacggggagg ttgagatgat
    15181 aaagcagttc ggctatgaag atttcaaagg gcggttgtca taaccggttt tgaaagacat
    15241 ccgggacaag ggaagatgac ttggatgagg gtagaggaaa tggagaaaaa gatgcaaaag
    15301 tgtgcagaag acccaaaaga gagaatgaca acgccgcaga cggacggatt ttttatgccg
    15361 ggggagtacg aaccgcatga cggctgcatt ctgatctggc cgtcgcgccc gggttcctgg
    15421 atttacggcg cacgcgatgc gcggattgca ttccgggatg tgattgcagc gattgcgcag
    15481 agtgaaaacg tatatgtggc agccgggcgg gatgccattg actccgcgcg agagatgctg
    15541 accggtgagg acgcgccgtg gaaaaagcgt gtgacggtct ttgaactgga gacagacgat
    15601 gcctgggcaa gagatgtggc accgactttt gtgaaagacg gcgccggcag ggtgcgggca
    15661 gtgaactggt catttaacgc ctggggagga tcggtggatg gactgtatgc atcctgggcg
    15721 ttggacgatg cgtttgcaaa ggcgtttgcc gcaaagtacg gctatgcgtg ttacgatgcc
    15781 gcgccgtttg tactggaggg cggatcgatt cacagcgacg gtgaggggac gcttctggtg
    15841 acggaggcgt gccttttgag tgcggggcgc aatccggggc ttacgcgcga ggagatcgag
    15901 gagaagctta gaacgtatct tggcataaaa aaagtgctgt ggctgccgcg tggaatctat
    15961 caggatgaga cgaacgagca tgtggataac gtctgcgcgt tcctgcgccc gggcgaggtg
    16021 gtgcttgcat ggacggacga tgaaacagat ccccagtatc cgctatcaca gcagacgctt
    16081 gcgtacctgg agggcgagac ggatgcgcgc ggaagaaagc ttgtcattca caagcttccg
    16141 attcccgatc atccggtctg cattacagag gaggaactgg cagggtattc gtttgccgaa
    16201 ggggaggatg agcgggaggc gggagagcgt cttgcggcat cctacgtgaa cttttatttt
    16261 tccaacgagg cagtcgtcct tccagcgttc ggcggggaga atgaggagag tgacaggcgc
    16321 gctgccgcac tgcttgcgca gtggaatccg gggcggaaga tcattccggt gcaggcgcgt
    16381 gcaattttag tcggcggcgg gaatatccac tgtattacac agcagatccc ggcggcaaaa
    16441 atgcagcagc aaaaatgcag cagcggtaaa gtggacagag acaaaaagag gaaaagagta
    16501 tgaacagagt gaaagtggcg gcaattcaga tgcgctgtgc ggcatctgtg gaggagaatt
    16561 taaaaaaggc ggaagccatg gtgcgaaagg cggcggcaga gggagcaaac gtgatccttc
    16621 tgccggaact ttttgagcgg gaatattttt gccagcagcg ccggtatgac ttctatcatt
    16681 atgcaaagcc tgtgatggag aacgatgcgg tgcgcatggg catgcggctt gccgcggagc
    16741 ttggcgtggt gctcccgatc agcttttatg agcgggatgt gaacaacctg tacaattcca
    16801 tcgcctgtat cgacgcggac ggaacggtgc tcggcgttta tcgcaagacg catatcccgg
    16861 atgatcacta ctatcaggaa aagttctatt ttacgccggg ggataccgga tttcaggtat
    16921 tttctacgcg ctacggcaga atcggcgtgg gaatctgctg ggatcagtgg tttccggaga
    16981 gcgcgcgctg tatggcgctt gcaggggcgg agctgctttt ttatccgacg gcgatcggat
    17041 cggaaccgat cttagagtgc gacagtatgc cgcactggag acgctgtatg cagggacatg
    17101 cggcagccaa tctgatgccc gttgttgcgg caaaccggat cggggaggag acggtagaac
    17161 cctgtgagga aaacggcgga cagcgttcgg cgctcgtttt ttacggatcg tctttcctga
    17221 ccgatgagac cggagaaatt ctggcggagg cagggcgcga cgaggaagag atactggtgc
    17281 aggaatatga cctggacgag ctggatgcca gacggctgga gtgggggctg ttccgcgaca
    17341 ggcgcccgga gtgctacggc atcatcagcg gcaggtaaaa gaaatatatt gttgacatgg
    17401 aaacaataat gagatacagt aggaactggg aacaaaatac catgttagaa aaaggaagag
    17461 tctgcatgaa agatcgggaa gagctgttaa aagaaatcgc gctcatgctg gagcggcagg
    17521 atatgctttc caaactgacg gaaaaccagt gtctggatga atacggctat tcggagacac
    17581 actgtatcga ctatatcgga agactggaac tgccgaacgt cacgaaggtg gcggagcaca
    17641 tggggatgac gcgcggcgcg atcagcaaga tgaccaagaa gcttcttgcc aaagggctga
    17701 tcgaaaaata tacgctggag acgaacaaaa aggaagtata tttcaagctc acggatcagg
    17761 gcaggctttt gtttgatgag catgcgaagc gccataagcg atgggagaag cgcgatatgg
    17821 aatttctggc gcgctattcc gtcgaggatg tgaggacggt gagccgtttt atgacggagt
    17881 tcaacggcta tctggaagag cagatcgaga cgatcacagg gacgcaggca gaaggatgat
    17941 attgtgtaat aggaacgaag tttcctgtta cacaaaaaag aatcctgcag gcaggattct
    18001 catgtgttac tgttgtatga aatgtaattg ttaagcgttt aacacttcaa gaagcgtaag
    18061 cagcttctct accgtgtcct ggctgatgtt gtttgctgcg ataaaattgc ttaccgtcgt
    18121 tgcaacatct tcggaagtct ctgcagtgga tgcggatgcc acggtgttcg tatcgcttcc
    18181 catataggag agaaccttct ggacataatt ctgtgtctcg ctaaacggtg gaataccgcc
    18241 gtatttatcg acatttgcgc tgccggcgtt gtatgccgca agtgcaagag aggtatcacc
    18301 gttgtacctg gcaagcagct gggagatcag attcgcaccg cccatgatat tctggtaggc
    18361 gtcgtaggaa tctgtgacac cgagagatgc tgcggtggca ggcatcagct gcatgatacc
    18421 gacggcaccg gcgctgctga cagcgcttgt attaaaattg gattctgctc ttgcgattga
    18481 ttttaaaaga gtggaggaga cgccgtaggt gtttgccgcc tcgtcaaaga tggcggaaag
    18541 gtcttcggag caggccgtgc tgccggagta ggcgtcggtg gcattcgtta aaacggaaga
    18601 aaagtcagat cccgcagcct gtgctttggc agcttcggcg gcagctctct ccgcttcggc
    18661 gcgggcagca gcctcggtgt tgatctgatc cacaaatgcc tgatcgtgat aatttaagat
    18721 cgtaatactc attggtaact cccttgaaaa caacttcact gaatgtataa ctagaaaaag
    18781 tatagcataa tttacgggat taggaaagaa aaaaatgaaa accaagcaag ccgaacagaa
    18841 agggacatat ttacgtgcat tccgggcagc atttccctac acggtaccgg tgctcaccgg
    18901 ctatctgttt atcggaatgg cgttcggagt gatgatacag gaaaaaggtt acaacttctt
    18961 gtgggcaatg ctcatgagcc tggtgatcta tgcgggcagc ggacagtatc tggcagtcaa
    19021 cttcttcgcg ccgggcgtca gccttttcaa tgtgattttc atggaattta tggtgaatat
    19081 ccgccatatt ttttatggat tgtcactgtt ggaacgtttt tccgagatgg ggaaaaagcg
    19141 gctctacatg atcttttccc tgacggatga gacctactca cttttctttg tcacaaaagt
    19201 gccgaaggat gtgaaggagg agcagttctt atttgcgatt gccgtgcttg accagagtta
    19261 ctggatcatc ggctccggca tcggcgccct gcttggaaat gtacttccgt tctccgcgga
    19321 gggcattgac tttgcaatga cggcattgtt tgtggtaatc atggtagaac agtggatgga
    19381 gaagcagaac cgtccgagcg tggtgatcgg gctggtatgt ggactggtgt gcaggctggt
    19441 gttcggagcg gacaatttta tccttccgac catgatatgc gtcatggtca tcctgctttc
    19501 ctgcaaaaaa atattcgata aaatgattcc ggaggacgga aaggaaggag gcgagccgga
    19561 gtgccagtaa gtgttggaag atcgcttgcg atcatattta ccgtggcggg aacgatattt
    19621 tttacccggc tgattccgtt tctgtttttc ccgaaaggaa aagagattcc gccgatcatc
    19681 cggtatctgg ggagggtgct gcccccggcg gtcatcggaa tgctggtgat ctactgcctg
    19741 aaaaatgtgt cggtgcttgc agtacctttt ggtctgccgg aattcattgc cgtggcggcg
    19801 gtcatcgtgc ttcatgtatg gaagcgcaac aatctgctca gcattggtgt cggaacggca
    19861 ctttatatgt ttttgataca agttgtattc taggaagaga ggaagaaccg tatgaagaag
    19921 aaaccatttg taaccaaaga acagttagaa gaaatcgtaa aaaaataccc aacgccgttt
    19981 catctctacg atgaaaaagg aatccgcgaa aatgcgaagg cagtgaagga agcatttgca
    20041 tggaacccgg gattccggga gtattttgcg gtaaaggcaa cgccgaaccc gttcattctt
    20101 gacattttaa aagaatatga ctgcggatgt gactgtgcgt cgctgacaga gctgatgctt
    20161 gcggattccc agggcttcga tggaaaacac atcatgtttt cctccaatga tacgccggcg
    20221 gaggaatttg catttgccaa tgagcttggt gcgatcatca atctcgacga ttttacacac
    20281 attgattttc tggaaaaaac gatcggcagg attccggaga cgatcagctg ccggtacaat
    20341 ccgggaggcg tctttaagat gagcaacggc atcatggata atccgggcga tgcaaagtac
    20401 ggttttaccc acgagcagat cattgaggga ttcaagatct taaaggagaa gggagccaag
    20461 cattttggcg tacatgcgtt tcttgccagc aataccgtga caaacgaata ttacccgaag
    20521 cttgcgagag aactgtttga actggttgtg gaactgcgcg ataagacggg atgcgatatc
    20581 cgttttatca atctctccgg cggtgtcggt attccgtaca caccggatca gacgccgaac
    20641 gacatccgtg tcatcggaga gggcgtccgg gtggcatatg aggagatctt agttccggcg
    20701 ggacttggcg atgtcgcaat ctacacggag atgggacgtt ttatgctggg accgtacggc
    20761 tgcctggtga caacggccat ccatgagaag catacccaca aggagtacat cggtgtggac
    20821 gcgtgtgccg tgaacctgat gcgcccggca atttacgggg catatcacca tattacggtg
    20881 atgggcaagg aggatgcgcc gtgcgaccac aagtatgatg tgacaggctc actttgcgag
    20941 aattgcgata agtttgcgat tgaccggatg ctgccgaaga tcgacatggg agatcttctg
    21001 gtgattcatg ataccggtgc gcatggtttt tccatgggat acaactataa cggaaaatta
    21061 aagtcagcgg aggtgctgct gaaggaagac ggatcgacac agctgatccg tcgtgccgag
    21121 acgccggagg actatttccg cacgtttgac tgctttgata tcttaaagga tatgaagcac
    21181 ccgaaataag cggcagatca ttccggaaaa agcacagcag cgaggatgag atatgtgcat
    21241 tgatacagaa cgttttgagc gtgccagggg cagagtcatt ggaatcgagc ggcagaggct
    21301 tggaatcggc acactctcgg agaagacggt acatgcagtg ctcaagaatt attatgcacc
    21361 ggatgaggat atgcatgaga tcccgattga gaattttgtt gcggatattt ttgacgggga
    21421 ggcagtgatc gagattcaga cgcggtcgtt ccagaatatg cggcggaaac ttgccgcatt
    21481 tctgccgttg tacccggtga ccatcgtcta tccgattccg catgtgaagt ggcttcactg
    21541 gatggatgag gagacggggg agatctctcc cgggcgcaaa tcgcccaaga agggaaatgc
    21601 ataccaggca ttcatcgaat tgtataagat ccggccgttt ctgaaagatc cgaatctgag
    21661 actacggctg gatctcattg acatggagga ataccgtctg ttaaacggct ggagccggga
    21721 caaaaagaag ggaagcgacc gcttcgaccg gataccgctt accttcgtgg aggaagtgcg
    21781 tgtggaccgg agggaggact acatgcagtt catcccctat gagattccgg aggagtttac
    21841 tgcgaaggat tttgcggcat gcgcgaagat tccggtgcgg ctggcacaga cggtgctctt
    21901 gattctgacg gatctattga ttgtggagcg gattggaaag cagggaagaa gttatctcta
    21961 ccggatctgc gagattgaat gaatctcttc ccaagcgggg cgttctgtgt tatactgact
    22021 gccggatgta tatttatgca gtatctatgt gagagataag gaagcatgag gtagatagta
    22081 cgatgaaaaa cacagcaatc aaattatccg gcatactgct tgccggagcg gtcttttttt
    22141 cgacgctgtt aggttacggc acacaggctg ccgcggcgac ggcgataggc agcgacacgg
    22201 aggcgggaca ggcatccggc gacggttctg ttgcgtcggt tgcggatctt ccgggaaagc
    22261 atatcggtgt acagctcggc acgaccggag atatcatggt cagcgactat gagacggacg
    22321 gctcgggcac ggtagtagag cgttacaata agggcgcgga tgccgtgcag gcattaaagc
    22381 agggaaagtt agactgcgtg attattgacg aattgccggc gctggcattt gtggagcaga
    22441 acgaagggct taagattctc gaggagaact ttgttgagga ggactatgcg ttcgtaatcg
    22501 caaagggtaa cgaggcactt gtggatcagg tcaatgagac gctgcgcgaa ctgaaggacg
    22561 agggtgttct cgataacatt gcgaagaatt ataccggaac ggacgaggag attggaaagt
    22621 atccgtatga aattctggat gtggaacgca cgaacggcac gcttaccgtt ggtacgaatg
    22681 cggagtttcc gccgtatgaa tactatgaag agggaaagat caccggaatc gacatggata
    22741 ttatgcaggc ggtctgcgac aaactcggca tggagttaaa gatcgaggac atggcgtttg
    22801 attccgtgat tcctgcggtg tccaccggaa aagtcgacat cggtgcattg ggttttacgg
    22861 tgacggagga acgcaaaaag aatgtgaact tcacggatac ctatgcaaaa tccaagcagg
    22921 tcatcatcgt gagagataca tctgtcacag cagagaagac cgggatcggc gagaagtttt
    22981 atgataactt tatcaaggac agccgatata cctatttgtt aaagggactt ttaaatacac
    23041 tcatcatcac cgtgtttgcg gtaatgatcg gtattgtgtt tggatttttg atcgcgattg
    23101 taagaaccaa ccacgacaga aacggcgggc ttacgatctt aaatgcactc tgcaaggcat
    23161 accttgccgt tgtgcgcggt acgccggtca tgattcagct tctgattatt tattatgtca
    23221 ttttccagag catcaatacg ggaaaactgt tcgtggcagt cattgcgttc ggactgaact
    23281 cggcggccta cgtggcggaa atcgtccggt ccggtattat ggcggtggac atcggacagt
    23341 ttgaggcggg aagaagcctc ggactaaatt ataagcagac gatgttaagc atcatcctgc
    23401 cgcaggcagt caaaaatatt ctgccggcac tctgcaatga gtttatcagt ctgttgaagg
    23461 agacttcgat cagtggttac atcgggctga tggatctgac caagggcgga gacatcatcc
    23521 gaagcgtgac gtacgaggcg ttcatgccgt taattgcggt cgcggccatt tatttcctga
    23581 ttgtcatggg actgagcaag gcagtcggac tgttggaaag gagattgaga agcaatgagc
    23641 gataatacgg taattctgga agtaaaagag cttcacaagt cttttgacgg tcatgaagtg
    23701 ttaaaaggaa tctctacgac gatcaaaaag ggcgatgtgc tggcgctgat tggaccgtcc
    23761 ggctgcggta aatccacgtt tttgcgctcc ttaaatctgt tggagattcc gacggcggga
    23821 catgtgctgt ttgagggaac cgatctgacg gacccgtcgg tggacatcaa tcatgtccgg
    23881 gagaagatcg gcatggtgtt tcagcagttc aacctgtttc cgaacatgac gattctggaa
    23941 aatatcatgc ttgccccggt aaaactcggc aagatgacaa aagaggaagc gaatacgcgc
    24001 gcgatggagc tgttaaagcg catcggtctg gcggataagg cgggcgcgta tcccgcgcag
    24061 ctttccggcg gacagaagca gcgcattgcc atcgtgcggt cgctggcgat ggacccggac
    24121 atcatcctgt ttgacgagcc gacctcggcg cttgatccgg agatggtcgg cgaggtgctc
    24181 gccgtgatgc aggaactggc ggaggatggc atgacgatgg tggtcgtgac acatgagatg
    24241 ggatttgcca gagaagttgc gaaccgtgtg atgtttatca acgacggcgt gatccaggag
    24301 gagggaaccc cgcaggagat ttttggcaat ccaaagagcc agagactgca ggagttttta
    24361 tcaaaggtat tgtaagaaga aataaggacg ggctgtccgg cgcaaaagag gtgccgcggc
    24421 ccgttttttg tgcaacaggc aaagaatgtg ttttgtatac tgcatcagga atacctcccg
    24481 caggcggaga gcggggcgga acatcgtttg caagatgtgc gattgtatga taagataaat
    24541 aacgattttt aggaacggaa tcgtaaggga aggaagaacg catatgaaat ggaataaata
    24601 cacgatagag acaacgacgg cggcggagga ctacatgagc gcgatgttag ccgacctcgg
    24661 cattgaggga gtggagattg aggataacat tccgctgtcc aaggaagatc aggcggatat
    24721 gttcatcgat tttctgccgg agcttccacc ggatgacggt gtgagccatg tcagctttta
    24781 tctcgaggat gacggcgagg atcgcaccga actgttaaag caggtaaaag aggcgctgga
    24841 ggatttaaga aaagtcgtgg atgtcggaag cggcgtgatc acctccgacc agacggagga
    24901 tctggactgg atcaacaact ggaagaaatt cttcagttcc ttctatatcg atgacatcct
    24961 gatcaaaccg acctgggagg aattaaagcc ggaggatgct gacaaatttt taatcgagat
    25021 tgatccgggt gtgtcgtttg gaaccggcaa gcatgagacg acgcagctgt gcatccgcca
    25081 gctgttaaag tatatccgag ggaacgatgc gtacacaccg gaaaaacgcg cgccgaaggt
    25141 actcgacgtc ggctgcggaa gcggcatttt atcgattgtg gcgttgaagc ttggcgcgtc
    25201 cgcggtagtc ggaacggatc tcgatccgga ctgcatgacc tccacacatg agaacatggc
    25261 ggtgaaccat ctggacgcgg cgctcggcac attttatgtc ggcaatctga tcgatgatgc
    25321 ggcattgcag gagaaagtcg gcacggagga atacgacatt gtggttgcca acattctggc
    25381 agacgtcatt attccgatgg caccggtgat tccggcacgc ttgaaacgcg gcggttattt
    25441 tattacctcg ggcatcatcg atttcaagga gaacgcggta aaagaagcga tcgaagcggc
    25501 cggacttacg gtggtggaga tcaatcatca gggcgagtgg gtgaacatta cggcgagaaa
    25561 gccggaataa ggaagacaat ccggaagaag gaaagacgac ccgaagaaat ggcaggaagc
    25621 ccggaaatga ggagtttatg tatcagtttt ttgtggaaga cgagcagatt gcaaatgatc
    25681 tggtgacgat tgagggaagc gatgtaaatc acatccgcaa tgtcctgcgc atgaaatgcg
    25741 gggaaaaagt gcgcatcagc agcacatccg gcaggaattt cttcggcacg attgaccgga
    25801 ttgcagagaa tgtggtggag gtgtgcatca cggaagagac ggctttagat acggaactgt
    25861 cctgccggat ctgcctgttt caaggacttc caaagagcga caagatggag ctcatcgtcc
    25921 agaaggcagt ggaacttggc gccgctgaag tgattccggt agcgatgaaa aactgcgttg
    25981 taaaactgga tgcaaaaaaa gcagcggcaa aggcggcgcg ctggcaggag attgcaaaga
    26041 gtgcggcaaa gcagtcaaag cgcagcagaa ttccggtggt gagagaaccg gtgaattacc
    26101 gggaggcagt cgcattggcg ggagagctcg atgtggtgct gctgccgtat gagaacgagc
    26161 gcggcatggc ggccacaagg gaagtgatgg agcggattgc accggggcag agcgtcggca
    26221 tttttatcgg accggagggc ggattcgatc cgtcggagat tgcgctggca aaagaggagg
    26281 ggatgcatct ggtgtccctc ggaaaaagaa ttttgcgcac ggagacggcg ggacttgcaa
    26341 ccctttccat tctgatgtat catatcgaga gtgtgtcgga agcggaagaa gagcgggatc
    26401 agccgtgatt ctgcgtcggc gtttgttaga aaggcatggt tttaaaacag atggaagcat
    26461 atttggataa ttctgccacc acccggtgca gtgagcgcgc caaaaacaag atggtgcaga
    26521 tcttaacgga agattacggc aatccgtcct ccctgcacaa catgggaaag acggcggagg
    26581 attatattaa agaagcaaaa gagcagatcg caaggacgct ccgctgcgat gagaaggaga
    26641 tcgtctttac gtcgggcggc acggagtcga acaatatggc gctgatcggc ggagcgctgg
    26701 caaacaagcg ccagggaaag catatcatca cgacgtcgat tgagcacgcg tcggtacagg
    26761 cgccgcttgc ctacttaaag gaactcggct atgagatcac ggaattgtct gtggatcatg
    26821 acggtattat ttcgctggag gaactgcggg atgcagtgcg ggaagatacg gtgctggtgt
    26881 ccatcatgat ggtgaacaac gagattggtg cggttgaacc ggtcgaggaa gcggcgaagg
    26941 tcatcaaggc gaagaatccg gacacgctgt ttcatgtgga tgcgattcag gcgtacggca
    27001 aattccgcat ctgcccgaaa aagatgggga ttgatctgct ctcggtgagt ggacacaaga
    27061 tccacgcgcc gaaaggaacc ggatttttat atatccgcga taaggtaaaa gtaaaaccga
    27121 tcatctacgg cggcggtcag cagaagggaa tgcgctccgg tacggagaac gttccgggcg
    27181 tggctgcact cggcgaggca gcggcggaaa tctatgagaa ctttgacgcg aaggtcgatc
    27241 atatgtatga gatcaagcag agattcatcg atgaagtgac acagatcccg ggagtgacgg
    27301 taaacggtaa aacgggacgg gactctgcac cacagattgt gagtatcacg atcgaggatg
    27361 tgcgaagtga agtgatgctc cattccctgg aagaatacgg catttatgtg tcagcgggaa
    27421 gcgcctgctc gtccaataag cctgcgccga gccgcacctt acagggcatc ggtctgccga
    27481 agcagaagtt ggagtccacg atccggatca gcttctgcgt caacacaacg gaagaagaag
    27541 tggattatgc ggtcgaaaaa atgaaagaga tcattccgtt ccgcagaaag ttcaccagaa
    27601 agtaaaggag agagtcatga catataaagc atttttgatt aaatatgcag agattgccat
    27661 caaggggaag aaccgttatc tgtttgagga tgcgctggtg agccagatga atcatgcctt
    27721 aaagaaggtg gacggcacgt tccatatccg caaggagcag ggcagaatct acgtcgagat
    27781 ggagggcgaa tacgattacg atggagctgt ggaggcactg cagcatgtgt ttggcatcgt
    27841 gggaatctgt ccggttgtgc tgttggagga cgagggcttt gatgtgctgg cgggggaagt
    27901 gatccgctat atcgacgagg tatacccgga caagcatttt acgttcaagg tcaatgcgcg
    27961 ccgtgcgaga aagaattacc cgttggagtc gatggagatc aatgcccaga tgggcgagcg
    28021 gattttggag gcgttcccgg agacgcgcgt ggatgtccac aagccgcagg tgatgtttaa
    28081 tatcgagatc cgcaaccaga tcaatgtgta ctcgacggtt attccgggac cgggcggtat
    28141 gccggtcgga acaaacggaa aagccatgct gctcttatcc ggcggaatcg acagcccggt
    28201 ggcaggctac atgattgcaa agcgcggtgt taccatcgat gcgacctatt ttcatgcgcc
    28261 gccttatacg tcggagcgcg ccaagcagaa ggtcgtggat ctggcaaaga tcatttccaa
    28321 atataccgga ccgatcaatc tgcatgtggt caattttacg gatatccagt tatatattta
    28381 cgaacagtgc ccgcatgagg agctgacgat tatcatgcgg cgctacatga tgaagctggc
    28441 ggagcatttc gcaaaagaga gcaagtgtct cggactgatt acgggggaga gtattggaca
    28501 ggtggcgagc cagaccatgc agtcgctcgc ggcaaccaat gaggtatgta cgatgccggt
    28561 ttaccgtccg ctgatcggat ttgacaagca ggagatcgtg gagatctcgg agaagatcga
    28621 cgcttatgag acctccatcc ttccttacga ggactgctgt acgattttcg tggcaaagca
    28681 cccggtgaca aagccgagct taaacgtgat tcacaatgat gagagaaagc tttccgagaa
    28741 gatcgatgcg ctgatgcagg aagccatcga tacggtggag gtaattcaca tcgaggcgta
    28801 gatgtgcatc ctcgcggtac gggtttatgt aataggaacg aagtctcctg ttacataaaa
    28861 aaacagccgc gggaaatccc gcggcgtgta cccctgttat gtatgaatta gattaagtat
    28921 ggctttaaag tctccataat ctcgtccatg ttgttctctg catggattgc aaggtcgata
    28981 ggcttggata aatctaaact gaagataccc atgatggact ttgcatcgat gacgtatctg
    29041 ccagagatca gatcaaaatc atattcatac tgcgtaattg cattgacgaa ggactttacc
    29101 ttgtcgatcg agttaaggga aatctgtact gttttcatga taaaaaacct ccttaggatt
    29161 atctgtttca agatagtttt atagtaatag tttttcgtgg aaaagtcaac acaaaaagcg
    29221 gatgaaacca taagaaagcg tgaacaaaaa gcaatacaga aatgaggaaa caagaatgaa
    29281 agcagcattg cataatttgg gttgtaaagt gaatgcatat gagacggaag ccatgcagca
    29341 gattttggag gaggcgggat atgagatcgt gccgttttcg gagtatgcgg atgtctatgt
    29401 gatcaataca tgctccgtga ccaatatggc ggaccgcaag tccagacaga tgctgcaccg
    29461 ggcgaaaaag cagaatccgg atgcgatcgt cgtgggagcc ggatgctatg tgcagaccaa
    29521 ggaggcacag gctctcgtgg atgagtcaat tgacatcgtg atcgggaata ataaaaagca
    29581 tgagctggtg ccgctacttc gggaatacga agcatcccac cgcaagatgg cgtgtgtggc
    29641 ggacatcaat cacgagaagc aggcatacga ggaattgtcg ctttcgcgca cggcagagca
    29701 cacccgggcg tttatcaagg tgcaggatgg ctgcaatcag ttctgcacat actgtattat
    29761 tccgtttgcg agagggcgtg tcagaagcag ggagcttccg gacgtcttac aggagatacg
    29821 gacgctggca aaaagcggct accgcgaggt ggtgctcacc ggaatccatc tgagttccta
    29881 cggtgtggac aacggggagt cgctgctgca tctgatcgag gcggtacatg agctggaggg
    29941 gatcgagcgg atccgcctgg gaagcctgga accgcgtatc gtgacggacg cgtttgcaaa
    30001 aagactctcg gagctgccga agatctgccc acattttcac ctgtcattgc agagcggctg
    30061 tgatacggtg ttaagccgca tgaaccggcg gtacgatacg gcggaatatg aggtgggctg
    30121 tgcgctgctg cgcaggtatt ttgaacatcc cgcaatcaca acggatgtca ttgtaggatt
    30181 cccgggggag acggacgagg aattttggac gacggagcgt tatctggagc ggattcattt
    30241 ctatgagatg catattttcc agtattcgag aagagaggga acgaaggcgg cggcaatgcc
    30301 ggatcaggtg ccggaggcgg taaaaaagga gcgcagcgaa aaactgcttg cactcggtca
    30361 caggatgtcg ggggagttcc gccggtatta tctcggcaga caggtgacgg cgcttctgga
    30421 ggaagagttt ttatatgatg gaaagcgtta ctacaccggg tacacaaaag agtatgtgaa
    30481 agtggcggta gagacaaaaa aagatctttc caacacgttt gtgacgggca ccttaaagac
    30541 acaattaaca gaagacgtct atcttttagt tgaattttaa gacaaactat attagaataa
    30601 aaacagcaat gctttttcga caagagagcg gtggctggca gcaccgcttt aaagtccggg
    30661 cagatataag ggcgtgacaa atatgcagga gatcaataac acacaatatt ttaaagtgga
    30721 aaaaggaccg gaacttcgcg tgagcgacgt gctcgcgatt gtttatcgtg cgcttatgga
    30781 gaagggatac aatccggtga atcagattgt tggatatatt atgtcgggag atcctactta
    30841 tatcaccagt cataataatg caagaagcct gatcatgaaa gtagaacgtg atgagctggt
    30901 agaggagatg ctgaaggctt acatcaggaa taacaactgg gaatagaaga tgcggatatt
    30961 aggtttggat tttggctcga agactgtcgg tgtggcagtc agtgatgaac ttatgttgac
    31021 ggcgcaggga ctggagatcg tgagaagaca gtctccgaac aagctgcgtc agacgctggc
    31081 aagaatagaa cagattgtaa cagaatatca ggtggagcgc attgtgctcg gctatcccaa
    31141 gaatatgaac aataccgagg gagagcgttg cgagaagacg aaagagttt
//
