LOCUS       c00264_gnlPro..         4661 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OMOMMHNM_264.
ACCESSION   c00264_gnlPro..
VERSION     c00264_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:32:03
            Original ID  :: gnl|Prokka|OMOMMHNM_264
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4661
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1044)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg264_1"
                     /sec_met_domain="IlvN (E-value: 3.4e-47, bitscore: 148.5,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.3e-42, bitscore: 132.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTTETVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQREGKTYDKAVADGWVPGETLFGIEEACEKGTIVMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGKAYERTIALGIGIGSGYLFETTFQREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHSPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYNSVKTGNEAQISIDSNSQPDYREKLNEELRQLRESEMWQTAVTVR
                     KLRPENN"
     protocluster    1..4661
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:4659]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..4659
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4661
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4661
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(1112..1855)
                     /locus_tag="ctg264_2"
                     /transl_table=11
                     /translation="MSEENRIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHANDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYENFSVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVTSDQPIATLT
                     VKYSDIDINGHVNSIRYIEHILDLFPIELYKTKRIRRFEMAYVAESYFGDELSFFCDEV
                     NANEFHVEVKKNGNEVVCRSKVIFE"
     CDS             complement(1861..2418)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg264_3"
                     /sec_met_domain="ALS_ss_C (E-value: 9.9e-20, bitscore:
                     59.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDIIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQENP
                     EASKLIRRYNARIVEVNPVFSIVEKNGMSEDITSLYGELKALNCVLQFVRSGRVAITTS
                     CFERVNEFLDGREAMYNQSKNQ"
     CDS             complement(2469..4163)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg264_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.5e-48, bitscore:
                     150.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLITGAEALMRSLEHQGVTTIFGYPGGSIMPVFDALYDHQNIL
                     NHILVRHEQGAAHAAQGYARVSGDVGVCLVTSGPGATNTVTGIADAMIDSTPIVVIAGQ
                     VGTGFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAVARAFYIARSGRPGPVVLDF
                     AKNAQVEKTKYEPTKVDFIRSYVPVPDADEESVQAAAELINNAERPLVLVGQGVELGNA
                     QSELREFIEKADMPAGCTLLGLSALPTEHPLNKGMLGMHGNLGPNINTNKCDVLIAVGM
                     RFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDVAVLGDCKETLASVTKLLKKNAH
                     AEWIDSFKEYEKVEEEKVIRPELHPATNSLSMGEVVRAVSDATHHEAVLVTDVGQNQMI
                     SARYFKYTKERSIITSGGLGTMGFGLPAAIGATFGAPERTVCVFMGDGGLQMNIQELGT
                     IMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKVASAYDIPSKRAFT
                     REELKEAIAEMLATDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             complement(4288..4659)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg264_5"
                     /sec_met_domain="ILVD_EDD (E-value: 3.3e-50, bitscore:
                     159.5, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="THEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGGTSGL
                     SIGHISPEAAAGGNIGKIVDGDIIEIDIPARKINVRLTEEELAARPMTPVTRDRYVPKS
                     LKAYASMVSSADKGAVRII"
ORIGIN
        1 ttaattattc tccggacgaa gtttacgaac agttacagca gtctgccaca tttcgctttc
       61 gcgtaattga cggagttctt cgttcaattt ttcacgataa tcaggttgtg aattactgtc
      121 aatagaaatc tgtgcttcgt taccagtctt cacactgtta tacaactttt caactaccgg
      181 tttaatagca tcgtggaatg ggcccatcca atcgagagca ccacgttgag cagtagtaga
      241 gcagttagcg tacatccagt ccataccgtt ctttgcgaac aacggcatca acgactgtgt
      301 cagttcttcc actgtttcat tgaatgcttc agaaggacta tgaccgtttt cacgcaatac
      361 ttcgtactgt gccagcaaca aaccttggat agcacccatc aatgaaccac gttcacctgt
      421 caagtcagaa gtagcttcac gttggaaagt tgtttcgaac agataaccgg aaccgatacc
      481 aatacccagt gcgatggttc tttcgtaagc cttgcctgta gcatcctgat agatagcata
      541 agaagagttc aagccacgtc cttcgaggaa catagtacgc aaagatgtac ccgaaccttt
      601 aggagcaacc atgataacgt cgatatcagc aggaggaact acacctgtac ggtcgttcca
      661 agtgatagca aaaccgtgtg agaaataaag agcttttccg gcagtcaggt aaggcttgat
      721 agtaggccat actgacatta ctgctgcgtc agacaacaga cacattacaa tagtaccttt
      781 ctcacaagct tcttcgatac cgaacaaagt ttcacccgga acccatccgt ctgctactgc
      841 cttatcgtat gtttttcctt cacgttgacc aacgattaca ttgaaaccgt tatcacgcaa
      901 gttcagtgcc tgtccaggac cctgtacgcc ataaccgatt acagcgattg tttcattttt
      961 caatacttca cgagcttttt ccaatggaaa ttcgtcacgg attactacag tttcagtagt
     1021 acctccaaaa ttcaactgtg ccattttctt tttgttttta gtttttgatg acttatgcca
     1081 tctgttatta attgatttta tattctcaca tttattcaaa tatcactttc gagcggcaaa
     1141 caacttcgtt gccattcttc ttcacttcta cgtgaaactc gtttgcgttc acttcatcgc
     1201 agaagaaaga gagttcatca ccaaaatagc tttccgccac atacgccatt tcaaaacgac
     1261 ggatacgttt ggtcttatac aattcaatcg ggaacaaatc aaggatatgc tcgatgtaac
     1321 ggatgctgtt tacatgaccg ttgatatcta tatcactgta ttttaccgtc agggtagcta
     1381 tcggctgatc gcttgtcact ttgatgcgtg aaggcttttc aatcgggcaa ggctcatcac
     1441 agacatagtc tacgatactt cccccatgca aagtcaacaa gtcggcaggc ttgcgggtat
     1501 taagattaat cattgcccat acggaacgtg cgtagccaat cttcttccca tccttatcaa
     1561 taatagcaaa attacggtcc gtaaacaaac ggtagacatt ttccacccac gtctgaaccg
     1621 agaaattctc atactgataa ggcatttcat ccaactcaat agccagacgt gaaagcaccc
     1681 atgtgtaatt atcctcattc agcgttgcaa taccaaaacc acggtcattg gcgtgaaaac
     1741 ctgcacaatt cagcagatga tttcccagta cccccatggt cagacgtccg ttgaagtcaa
     1801 catggaacgg ttctgccaca aactgataag tccctattct attttcttca ctcattattc
     1861 ttattggttt ttactttggt tatacatagc ttcccgtcca tcgagaaact cattcacccg
     1921 ttcaaagcag ctggtagtaa tcgctacacg tcccgaacga acaaactgca aaacacaatt
     1981 caaagccttc agttcaccat agagcgaagt tatatcttcg ctcattccat ttttctcgac
     2041 aatagaaaat accggattga cttccactat acgtgcattg tatctacgaa tcagcttgga
     2101 tgcttccgga ttctcctgaa aagcaggagt agacacctta tataatgcaa tctcgtggaa
     2161 ataaatctca tcctctgtga aataatgtgc ctgaatcacg tcgatcttct tttcgatctg
     2221 tttcactacc ttctcaatga tgtccttatc agtccaggct gttattgtat acttatgtac
     2281 acctttaata gaagaagcag atacattcag actctcaata tttatttgcc gacgggtaaa
     2341 tacagcagtt acctgattca gcaatccagc tatattctcc gaatgaacaa tgattgtata
     2401 taacgtttta tcactcataa ctctaatttt ttaaatgcga actctccatt ctcaactctc
     2461 aacttctcct agcactccag caacatctgg tttaccgaac cacccggagg agtcatcggc
     2521 aaaacattgc cttcttccac cacgcaggct tcgagcagga acggaccatc cgttgccagc
     2581 atttcagcaa tagcttcctt cagttcttca cgagtgaaag cacgtttgga aggaatatca
     2641 taagccgagg ccactttcat ataatccgga ttcaacatcg gggtaaacga atagcgacgg
     2701 ttgaaaaaca tagcttgcca ctgacgtacg tttcctaggt aattattgtt cagacagata
     2761 atcttcaccg gagctttctg ctccataatc gtacccaatt cctgaatatt catttgcagt
     2821 ccgccatctc ccataaatac gcatacggta cgttccggtg ctccgaaagt tgccccgata
     2881 gctgcgggaa gcccgaagcc cattgttcca agtcctccgg aagtaatgat actgcgttct
     2941 ttcgtatatt taaagtagcg tgcagatatc atctgatttt gacctacatc tgttaccaaa
     3001 acagcttcat ggtgagtagc gtcactaacc gcacgtacca cttcccccat actcaaagag
     3061 tttgtggcag gatgaagttc tggacggatt actttttcct cctctacttt ctcatattct
     3121 ttgaagctat caatccattc ggcatgagcg ttctttttca ggagtttcgt cacagaagcc
     3181 agtgtttcct tgcagtctcc caatacagct acatctacct ttacattctt attaacttcc
     3241 gcaggatcga tatcaaaatg aatcactttt gcctgtttgg cgtaagtagc caaattaccg
     3301 gtcacacggt cgtcaaaacg cataccaaca gcaatcagca catcacattt attggtattg
     3361 atattcggtc ccagattgcc gtgcataccc aacatacctt tattcaacgg atgttctgtt
     3421 ggcaaagccg aaagtccgag cagcgtacaa cccgcaggca tatccgcttt ttcgataaac
     3481 tcgcgcaatt cgctctgtgc atttcccagt tcaacacctt gtccaaccaa tacaagcgga
     3541 cgttcagcgt tattaatcag ttcggcagca gcctgtacag actcctcatc cgcatcggga
     3601 acaggaacat aactacggat aaaatcgact ttcgtcggtt cgtatttcgt tttctctact
     3661 tgcgcatttt tggcaaagtc cagtaccacc ggccccggac gaccactacg agcaatgtaa
     3721 aacgcacgtg ctaccgccca ggctacatct tccgcacggc gaatctgata actccattta
     3781 gtgattggct gggtgatacc taccaagtca acttcctgaa aagcatccgt cccaagaaag
     3841 cctgttccta cctgtccggc aatcaccacg ataggcgtac tatcgatcat cgcatccgca
     3901 atgcctgtta ccgtattggt tgctccggga ccgctcgtca ccaggcaaac acctacatca
     3961 cccgatacac gggcataacc ctgtgcggca tgggcggctc cctgttcgtg acgaaccaag
     4021 atatggttca atatattttg atgatcgtac aaggcatcga ataccggcat aatagaacca
     4081 ccggggtaac caaagatggt agtcactccc tgatgttcca aggagcgcat caaagcctct
     4141 gcacctgtta ttaaatcttt catattagtt gatagttgat aaatgataaa tgatagttga
     4201 gaaatgacag ttgaaaatga atggtttaca atcattgcgc taagtgctgc gcagctaact
     4261 attacctatc aactatcacc aactatatta tataattctc actgctccct tatcggcaga
     4321 gcttaccatg ctggcatacg ccttcaggct cttcggtaca taacggtcac gagtgacagg
     4381 agtcatcgga cgagccgcca gttcttcctc cgtcagtcgc acgttaatct tccgggccgg
     4441 aatatcgatt tcgataatgt ctccgtctac aatttttccg atattgcctc cagctgccgc
     4501 ttcaggagaa atatgtccga tactcaatcc ggaagttcca ccgctgaaac gtccgtcggt
     4561 aatcaaggca cattcttttc cgagatgacg ggattttata taagaggtag gataaagcat
     4621 ttcctgcata ccgggaccac ccttcggacc ttcgtgcgtg a
//
