LOCUS       c00104_gnlPro..        12137 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DLNLBPLL_104.
ACCESSION   c00104_gnlPro..
VERSION     c00104_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:56:02
            Original ID  :: gnl|Prokka|DLNLBPLL_104
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12137
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12137
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[948:3517]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      949..3517
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     protocluster    1..12137
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3284]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      3..3284
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="2"
     cand_cluster    1..12137
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="interleaved"
                     /product="OD_unknown"
                     /product="porA"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12137
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="OD_unknown"
                     /product="porA"
                     /region_number="1"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             complement(3..920)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: Succ_CoA_lig"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: CoA_binding_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_1"
                     /sec_met_domain="Succ_CoA_lig (E-value: 5e-49, bitscore:
                     155.6, seeds: 149, tool: rule-based-clusters)"
                     /sec_met_domain="CoA_binding_2 (E-value: 5e-22, bitscore:
                     68.6, seeds: 225, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLNKLLKARSLAVVGASEKSGFGGDTCRNILEYRKDLSRVYFVN
                     PGRDTVLGRKCYKSLSEIDDEIELAIICTSQATVCGLLREAKTKGCGGAVVFASGYSET
                     GDEKGKEAEEELKALAKELDIAVLGPNCGGFNNYVDDVISFAFPVEKRDRKGSIGFISQ
                     SGQFCINLMDSSDMRFSYAISIGNGKIVTLEDYLDFLVEDENTTVIAIYMEGVQDAENF
                     ADCLKRAAEKRKPIVIQKGGRSEKGGKIAASHTGALAGSDRAYDAVFDKFGVIRADDMQ
                     ELMSTALLLSTLKKLPAKAAFASMN"
     CDS             complement(949..1479)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_2"
                     /sec_met_domain="POR (E-value: 4.1e-38, bitscore: 121.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEIICAGFGGQGVLITGMILAYCGMQEGKYFTWYPSYGSEMRGG
                     TANCNVKISEEEIASPYAKHLDILVSMNDVAIDKFEPTMKPGAVLVANSSLLDETRIFR
                     DDIKVVKVPATEIASGLGNPKGTNIVMLGALCKETGLFEKNFMKHSIDEYFAKKGKVNP
                     KNALCFDAGVKAV"
     CDS             complement(1476..2216)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-27, bitscore:
                     86.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKLKAPETVTFRPTSFCPGCGHGIAARLIGEIIDEMGLQQDFIPT
                     VDVACGALNMDTWRFDTVMAAHGRPVVVAIGVKKVRKDKLSVAYIGDGAAYAIGMAETM
                     HAALRNDNVVVIVMNNGVFGMTGGQMAPTTLIGQKTTSSPKGRDPQKQGEPFDVVKALG
                     QFDIAYLARASLDSPAAVVKAKKYIKKAFEKQLNNEGFCLVEILAPCPTNWGLSPVDSL
                     KHIREKTLSYYKVGEFVDKKGEEE"
     CDS             complement(2229..3284)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_4"
                     /sec_met_domain="PFOR_II (E-value: 6e-24, bitscore: 74.3,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 2.1e-46, bitscore: 148.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAEKVMMKGNEALAEAALRAGCRFYSGYPITPQTEILEYLSWRM
                     DEVGGEFVQTESELAGVNMLYGAASAGARVLTSSAGPGFALKQEGISYLCAADLPAVLI
                     DVMRIGNGLGDIAQGQGDYWQLTRGGGNGDYRTIVLAPNSVQESADLIGDAFDLADKYL
                     HPVIIASDAAIGQMMEAVCFQEMKEDNIDKFDWSVKGCKPGDKQRIISNVCFYGHPDYE
                     DYLRNKYKTIEDNEQRWESIRTEDAEIILVAYGISSRVAKEAVRNGRKQGLKLGLIRPI
                     TLWPYPVKAFQNLSEDFKGFISVEMNILGQMVDDIKLATDAKYPIEFYGTFFDVPESDR
                     IIEIAKEMIER"
     CDS             complement(3296..3517)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_5"
                     /sec_met_domain="Fer4_7 (E-value: 2.7e-14, bitscore: 43.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.1e-10, bitscore: 31.0,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.1e-06, bitscore: 16.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPERKDIMQKLKLNVERCKGCGYCVDACKQGALSQPGKLNKKGYS
                     IVVADEEKCIQCGMCYRMCPDCVIEILE"
     CDS             complement(3523..4791)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 102.9; E-value: 5.9e-32)"
                     /gene_kind="transport"
                     /locus_tag="ctg104_6"
                     /sec_met_domain="MFS_1 (E-value: 1.3e-32, bitscore: 102.9,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSRVKRYVAITALGLVYGTMFNLPYIKYVFYDAMIDGMGVSNTK
                     LGLLLTVYTIVSTAGLLPGGWIADRFKTKGIIVGSAFLNGIICFFFMFTMKNYACAMIT
                     WIVSAIAGVTAFWAAILKAVRLISPEDEQGRAYGFWEGVCGLSATIGNFVALYVFSRFD
                     NSTSALKGAVASMGFMCIIGGLLVWWLYDENITSTDERGEERKQVSIKETFAVFKLPKL
                     YLSCIIVFCSYGFFSSQSFLTPYFTNVLGAAVTFSGVLAIFRSYGLKILGGPVGGVIAD
                     KLHSPSKLAIGCYVIMAAAVIYIANAKGGSELITVLTVLSLILATVCFMARGTMWATIG
                     EAQIPPEISGTAISVASIIGFNIPDTFLPPLLGSWLDKYGNTGYQYIFNFLIGLCVVGV
                     IAALAMVLSNRRSANKKLTVNQG"
     CDS             5205..5930
                     /locus_tag="ctg104_7"
                     /transl_table=11
                     /translation="MFDVIGNKKNYEYIVEQIKDMIIDGKLKVGERLPTEKELSENFGV
                     SRTSVREALKALEVIGICESRQGGGNFIVNKVQERTTNNLSLLYTLNNGKIDDLIQLRR
                     CIESESIRNIIEEGNEEVIRELGEIIEHYNASTTSQERTDWDRQFHAKIIESSGNIMFI
                     FLLNALSYLYNLNISLVSKVIEDAYPTDFLVQEHNELYEAIKTRDLDLARKCIDEHFSF
                     TDDDRDALNVLQSIAKNPL"
     CDS             complement(6004..7590)
                     /locus_tag="ctg104_8"
                     /transl_table=11
                     /translation="MGENMDENTNKRTANIRLPESFGDRISFLRKLKELTQAQLAEKLG
                     ISAQAVSKWESGLSCPDIMMLVPLADIFGVSTDVLLAGGQLTGYGMSSGEEAAEASKET
                     LGLGRLEWQAEVEWQIRPEEGTNEKGQTVPEDVAKSENGAMPEDVAKSENGAMPEDVAK
                     SENGAMPEDVAKSENEAMPEGGTKSEDGAEPESVVKSEDGAIPEGAVKSEDGAGPEGRT
                     KSEDAARSDSAAKSEDGIRPESVERAEDEAGQKGKAEEHTGKEDAAETRSQFGQGEQGN
                     KTESGYRQSDSDRRKWQEDWKNGTLEVRKVFRENNVMIHSLHIDIGMADAIIREGDEFA
                     LDLSCYPNGDCREEVRDGVWKIKDRGYKDLFLLSNITNIFSERKVIIIIPRGYHFKDVK
                     IKLGAGKLVGRGILTDASSLDLGAGEIILADYYSGAAKVKCGMGKVMLEGQLRGRCKLD
                     CGMGEIAASLVSPSEYGYRVKVGMGDVRVGDNQFGGMGGSYKVNTSAENFFDINCGMGA
                     VKVLFGEHSEG"
     CDS             complement(7927..9114)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SBP_bac_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1044:Bacterial extracellular solute-binding protein
                     (Score: 59.4; E-value: 1.9e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg104_9"
                     /sec_met_domain="SBP_bac_1 (E-value: 4.4e-19, bitscore:
                     59.4, seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINLRLWHPWENEGEAYKKSFLEAVEEYNETHDRIQIQAEGTEME
                     LYREKLPSAIASNDTPDIYFCFGDSYLRGAVSSGKLLKMNEFLSDDTGSRLHADVLESM
                     TYEGGIYGLGFSESIAVLFVNEDMFEAYGCRVPTDWEELLEVCREFLARDITPFACSGD
                     ADTGFRLYLESICVSEAGSETCAKVLSQKGTEEETAAFAAGVDKFCRLRDMGAFGEPLF
                     SRSTQDVENDFYLSKIPMYLAKSDFTGNIVRENNPLHGKLSAVLFPGTHSQGEVLGGIS
                     DIFVVNRAAEYPKETVQALEEVLQNFAGKLYESGAGIPVWDTGDAKDPKDDVYWQIRSI
                     ANSAHNRMPYWEFYLDRRRAEMFMKSSGELGEGIITQEQFVRGLCGETEETADGW"
     CDS             complement(9128..9226)
                     /locus_tag="ctg104_10"
                     /transl_table=11
                     /translation="MAENFFIGVFISIGSDNRVLPQVFSKAGERQQ"
     CDS             complement(9266..9919)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg104_11"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 2e-17, bitscore:
                     54.1, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRILCYGDSNTWGHNPEPDGENFRYEDDVRWTGVLQKCLEGKAK
                     IIEEGLCGRSVMFDDPTSPDRNGRKFLNCSLQSHQPLDLVVLMLGTNDVRHIFTPSVKE
                     IAAGMVNLVRMARNREAYWVGKTPQVLVIAPPPVRDEIAGSDFYGMYDEESVRKSKALY
                     GAYETALKDIEGVYLMDAGSAAEVSVKDCIHLSSKGHSNLGKAAAEYIKKILKI"
     CDS             complement(9926..10768)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 69.5; E-value: 9.9e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg104_12"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.2e-22, bitscore:
                     69.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRYRVKKRVFSFLKAFMLLLLVVIIAFPFWQLIVSSMLDTNAII
                     SYPPKFWPSGGSLSNYTEVLKMQGGAYLRWMLNSIFVAGSNTVLVVLVASMAGYAFAKR
                     KFPGSRVLFNVVVATQIIPSVTTLIPLFLIVSKLGWVNTYKSLIFPGVASAFGVYMMTQ
                     FMKDIPDSLLEAAKIDGCSNYGTFFKIVLPITVPQLSLLAIFNFTQQWGSLTWPLITVN
                     ETMMKTLPLGIASMKDLNGTLTGTIMAASMISFIPLLIAFIFASDKFIEGMTLGAVKG"
     CDS             complement(10749..11762)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 53.3; E-value: 9.3e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg104_13"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.1e-17, bitscore:
                     53.3, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVFKRPDRKRGFCSEGLNLHCKGPSAVWEDGVFIMNKRKWKEYAV
                     SYSFLLPFAVFFIVFTIVPIGYVFYLSLHDGNFLQAQFEWVGLKNFKDVLQTPDFQNAF
                     KNTFIYMLIEVPVSQFLGIFFALLIKKKTRLSHACEVVYFLPMLISMVVASVLISYILS
                     NNGPLNMLFQVLGMKPISWLNGRFSAKMAVMILELWKGGTFFVFVYMSAMRSLPADCLE
                     SSRIDGANVVQETIYVVLPLIRNAIILCVTMNTIWQFQIFESVYMLTNGGPLGATQTVI
                     YEIYQYSFKYYRVGFGAAASLVFLLVILLIYGLENLLLGERDKSKRRGKKYEQIQG"
     CDS             complement(11779..12135)
                     /locus_tag="ctg104_14"
                     /transl_table=11
                     /translation="WNFANIGMLSISSQTKYPDEAWKFVEYITRPEVEKIYLSEVGFFS
                     PQLATNDMMYEGDEIMAVAAEGIKKLQVSPASDYANAMLQNLKIMYENVARGEKSPADA
                     IQAMYDSMKAISGE"
ORIGIN
        1 atattcatag atgcaaaagc agctttggca ggcagtttct ttaatgtaga gagaagaagt
       61 gctgtggaca tcagttcctg catatcatct gcccggatga ctccgaattt atcaaaaaca
      121 gcatcatatg cccggtcaga gcctgccagt gctcccgtat gggaggcggc aatctttccc
      181 cccttttcac ttctgccgcc tttttgaatg acgatgggct ttcttttctc agcagccctt
      241 ttcagacagt cggcaaaatt ctctgcatcc tgcacacctt ccatgtaaat ggcgatgacc
      301 gtggtattct catcctctac caaaaagtcc aggtaatcct ccagtgtcac aattttaccg
      361 tttccgatag aaatggcgta agaaaatctc atatcactgc tgtccataag atttatgcag
      421 aactgaccgc tctgggaaat gaatccgata cttccttttc tatccctctt ctccacagga
      481 aacgcaaaag agatcacgtc atccacataa ttattgaacc ctccgcaatt cggccccaaa
      541 accgctatat ccagttcctt agccagcgct ttcagctctt cctccgcctc ttttcccttc
      601 tcatcacctg tctcactgta accactggcg aagacaacag cacctccgca gccttttgtt
      661 tttgcttccc tgagcagacc gcatactgtt gcctgggaag tacagatgat cgccagctct
      721 atctcatcat caatctctga taaactttta taacattttc tgcccagcac ggtatccctg
      781 ccggggttta caaaatacac cctgctcaga tcttttctgt actccagaat gtttctgcag
      841 gtatcccctc cgaatcctga tttctcgctg gcacctacaa cagcaaggga cctggccttc
      901 agcagtttat ttagatccat atattcacct gctttctgtg aaacacattt acacagcttt
      961 tactcctgca tcaaaacaaa gggcattctt tggatttacc ttcccttttt tcgcaaaata
     1021 ctcatcaatg gaatgcttca taaaattctt ctcaaacagt cctgtttctt tgcagagcgc
     1081 cccaagcata actatattgg tgcccttggg atttccgaga cccgatgcga tctccgtagc
     1141 cggtactttt accaccttga tatcgtctct gaatatccgt gtctcatcta gaagcgagct
     1201 gtttgccaca aggacagccc ccggtttcat cgtcggctca aatttatcaa tggccacatc
     1261 attcatggaa accagaatat ccaaatgctt cgcataaggg cttgcaatct cttcctcact
     1321 tatctttaca ttacaattgg cagttccccc tcgcatttcg gagccataag aaggatacca
     1381 tgtaaaatat ttgccttcct gcataccaca gtaggccaga atcattccgg ttatcaatac
     1441 accctgaccg ccaaatcccg cacaaataat ttctgtcatt cttcttctcc tttcttatct
     1501 acgaattctc ctactttata gtaggaaagg gtcttctcac gaatatgttt caggctgtcc
     1561 accggcgata atccccagtt ggtgggacag ggtgccagaa tttcaaccag acagaatcct
     1621 tcgttgttca actgcttttc aaatgccttt tttatgtatt tttttgcctt gactactgct
     1681 gccgggctgt caagagatgc acgggcaaga tacgcaatat caaattgtcc aagagctttt
     1741 actacgtcaa acggctcccc ctgcttttgg gggtctctcc cctttggtga ggatgtggtc
     1801 ttctgtccga tcaatgtggt aggcgccatc tggccgccag tcatgccgaa cacaccgtta
     1861 ttcataacga taaccacaac attatcattg cgcagcgccg catgcatagt ctcagccata
     1921 ccaatggcat atgcagcccc gtcaccgata taggccacag ataatttatc tttccggacc
     1981 ttcttcacgc cgatggcaac caccacaggc ctgccgtggg ctgccataac cgtatcaaat
     2041 ctccaggtat ccatatttaa ggctccgcaa gctacatcta cggtggggat aaaatcctgc
     2101 tgtaagccca tttcatctat gatctcccct attagtctgg ccgcgatccc atgcccgcag
     2161 ccgggacaaa atgaggttgg tctgaaggta actgtttccg gtgcttttaa tttcactgac
     2221 ataaccccct atctctctat catttctttg gcaatttcga ttatcctatc actctcaggc
     2281 acatcaaaga acgtgccata aaattctatg ggatatttcg cgtctgtagc cagcttgata
     2341 tcatctacca tctgccccag gatgttcatt tccacactga tgaatccttt aaaatcttct
     2401 gacaggtttt ggaatgcctt tacaggatac ggccacaggg tgattggacg gataagcccc
     2461 agctttaatc cctgttttct tccgtttctg acagcttcct tggctactct tgaggaaatt
     2521 ccataggcca ccagtatgat ctcagcatcc tctgtccgga tactctccca ccgctgttca
     2581 ttgtcttcta tggttttata cttgttccgg agataatcct cataatcggg gtgtccatag
     2641 aaacatacat tcgatatgat cctctgcttg tctcccggct tgcatccttt tactgaccag
     2701 tcaaatttat caatattatc ctctttcatc tcctgaaagc atactgcctc catcatctgt
     2761 ccgatagccg catctgatgc aatgatcaca ggatggaggt atttgtctgc cagatcaaag
     2821 gcatcaccga tcaggtctgc actctcctgt acactgttgg gcgcaagaac aattgtcctg
     2881 tagtcgccat tgcctccgcc tctggtaagc tgccagtaat ccccctgtcc ctgggcgata
     2941 tcccccagac cattgccgat cctcattaca tcgatcagaa cagccggaag atctgccgcg
     3001 cacagataag agatgccttc ctgttttaat gcaaaccccg gtcctgcaga gcttgtaagc
     3061 actctcgctc ctgcagaagc cgctccatag agcatattga ctcctgccag ttcagattct
     3121 gtctgtacaa actctcctcc cacttcatcc attctccagg acagatactc caagatctct
     3181 gtctgaggcg taatgggata tccgctgtaa aatctgcagc ccgcacgcag tgctgcttcc
     3241 gctaaagctt catttccttt catcatgact ttttccgctg ccattgtctt ccctcctatt
     3301 ccaaaatttc aatcacgcag tccggacaca tacggtaaca cattccgcac tgtatacatt
     3361 tttcctcatc ggccaccaca atactgtatc cctttttatt cagtttaccc ggctgtgaca
     3421 aggctccctg cttacaggca tcgacacagt atccgcatcc tttgcagcgt tccacgttca
     3481 gtttcagttt ttgcataata tccttccttt ccggcaaaat ttttatcctt ggtttacagt
     3541 taacttttta ttggctgatc tcctgtttga caacaccatg gcaagtgcag ctatcactcc
     3601 caccacacac aatccaatga ggaaattaaa tatatactga tatcccgtat ttccgtattt
     3661 gtccagccaa ctgcccagaa gcggcggcag aaaagtatcc ggtatattaa aaccgataat
     3721 agacgccact gaaatagctg ttcccgatat ctccggcgga atctgtgcct ctccaatggt
     3781 agcccacata gtacctcttg ccataaaaca taccgttgcc aggatcagag acaatactgt
     3841 gagcactgtg atcaactcac tgccgccctt tgcgttcgct atataaatca ctgctgccgc
     3901 catgatcaca taacacccaa tggccagttt agacggagag tgaagcttat cagcgatcac
     3961 accgcccaca ggacctccca ggatcttaag accataactc ctgaaaatag ccaggacacc
     4021 gctgaaggta actgccgccc cgagaacgtt ggtaaaataa ggtgtcaaaa aggactggct
     4081 gctaaagaat ccgtaactgc agaacacgat aatacaactg aggtaaagct tcggcagctt
     4141 aaatactgca aatgtttctt taatacttac ctgctttctc tcttctcctc tttcatctgt
     4201 ggaagtaata ttctcatcat agagccacca tacaagtaaa ccgccgatga tacacataaa
     4261 tcccatactg gccactgccc ctttaagcgc tgatgtggag ttgtcaaacc ttgagaaaac
     4321 atacagtgcc acgaaattgc cgatggtggc tgacaacccg cacacacctt cccaaaatcc
     4381 ataggccctg ccctgttcat cctcaggcga tatcagtctg acagccttca gaatagctgc
     4441 ccaaaatgct gtaacacctg caatggccga tacgatccaa gtaatcatgg cacacgcgta
     4501 attcttcatt gtaaacatga agaaaaaaca tatgatacca ttcaaaaacg cgctgcccac
     4561 aataattcct tttgtcttaa acctgtcggc gatccatccg cccggaagca gccccgctgt
     4621 actgacaatg gtatagactg taagcagcaa acccagtttc gtattgctca ctcccattcc
     4681 gtcgatcatc gcgtcgtaaa atacatactt gatatatgga agattaaaca tcgtgccata
     4741 taccagcccc agcgcagtaa ttgcaacata acgtttcact ctgctgttca tgctttaact
     4801 cctttcgtat ttattacatt ttcgggaacc attatttgta ttccatagta actgtgcagc
     4861 ggccttatgc tcacaggcaa aaaaccatgc aaaaccgcag ttacaattca ttacaattca
     4921 ttatcttgac gatatttctg aacaatttac ttttctcatt gttcatatta tgatattgta
     4981 atattgtcat acaaatttat tatggttata aactaccaca gaaaatgtca tatgtcaatt
     5041 gaatttatgc attttccctt gttaacttat taacccattt gttataagtg ctttattatt
     5101 ttcattgatt gtggtaaaat tataacaatt atacaaaaca caggcgtgaa cagcctgcct
     5161 tttttaataa atcatgtaat agatgcacaa aatcggagga tactatgttt gacgttatcg
     5221 ggaacaaaaa gaattatgaa tatattgtag aacagatcaa ggatatgatc attgacggaa
     5281 aactaaaagt tggagaacga cttccaacag agaaggaact gtcggagaat ttcggagtga
     5341 gccgtacttc tgtaagagaa gcgctgaaag cacttgaagt tataggaatc tgtgaaagcc
     5401 gccagggggg cggaaatttt attgtaaata aggtacagga gagaaccacc aataaccttt
     5461 ccttactgta tactctgaat aatgggaaaa ttgacgatct gattcaattg agacgatgta
     5521 ttgagtctga atccatcaga aatatcattg aggaggggaa tgaagaggtg atccgggaac
     5581 tgggggagat catagaacat tacaatgcca gtaccacctc acaagagcgg acggactggg
     5641 atcgtcaatt tcatgccaag atcattgaat cctcgggaaa tattatgttt atctttctgc
     5701 tcaatgctct gtcctacctc tataacctta atatatcact ggtttccaaa gtgatcgagg
     5761 atgcctatcc cacggatttt ctggttcagg aacacaatga attatatgag gccataaaaa
     5821 ccagggatct tgatctggcc agaaaatgta ttgatgaaca tttttccttt acagatgacg
     5881 accgggatgc gctgaatgtc ctgcagtcca tagcaaaaaa tcccctgtaa gtatgatcca
     5941 gtaaaaaaca aagcgggaac ccactaaaat ctatggggtt cccgctgttt ttccgcagct
     6001 tatctatcct tcgctgtgct ctccaaacaa tacctttact gctcccattc cgcagttaat
     6061 atcaaagaag ttttcagcac ttgtattcac tttataagaa ccgcccatgc cgccgaactg
     6121 gttatcgccc actctgacat cgcccattcc caccttgact ctatagccat attcagaagg
     6181 tgacacaagg ctggccgcga tctctcccat gccgcagtcc agtttacatc tgccccgaag
     6241 ctggccttcc agcataactt ttcccatgcc gcacttcacc tttgcggcac cgctgtagta
     6301 gtcagccagt atgatctcac cggctcccag gtccagactg ctggcatctg tgaggattcc
     6361 tctgcccaca agcttgcctg cgcccagttt tattttcaca tctttaaagt gatatcctct
     6421 ggggatgata atgatcactt tcctctccga gaaaatattg gtgatattgc ttagtaagaa
     6481 caaatcctta taccctctgt ctttgatctt ccagactccg tccctcacct cttccctgca
     6541 gtcgccattg ggatagcagg acagatcaag ggcaaactca tctccctcgc ggattatggc
     6601 atctgccatg ccgatatcaa tgtgaaggga atggatcatc acattatttt cacggaaaac
     6661 ctttctgact tccagcgtac cgttcttcca gtcctcctgc cacttcctcc tgtcggaatc
     6721 actctgccgg tatccgctct cagtcttatt cccctgttcg ccttgcccaa actggctccg
     6781 tgtttcggcc gcgtcttctt tacctgtatg ttcttctgcc ttacccttct gcccggcttc
     6841 atcttctgct ctttctacac tttccggccg gattccatcc tctgatttag ctgcactatc
     6901 tgacctggct gcatcctctg attttgttct cccctccggc ccggctccat cctctgactt
     6961 tactgcaccc tccggtatgg ctccatcctc cgattttact acactttcag gctcggctcc
     7021 atcttctgat tttgttccac cctccggcat ggcttcattc tctgattttg ccacgtcctc
     7081 cggcatggct ccattctctg attttgccac gtcctccggc atggctccat tctctgattt
     7141 tgccacgtcc tccggcatgg ctccattttc tgattttgcc acgtcctccg gaacggtctg
     7201 ccctttttca tttgtaccct cttccggtct tatctgccat tcaacttcag cctgccattc
     7261 cagcctgccc agtcccagtg tctctttaga tgcttctgct gcctcctcgc ctgaagacat
     7321 tccatatccc gtaagctgac cgccggccag cagcacatct gtgctgactc cgaatatatc
     7381 cgccagagga accagcatca taatatccgg gcaggagagt ccgctctccc atttgcttac
     7441 agcctgtgca gagatcccca gtttttcagc aagctgtgcc tgagtaagtt ctttcagctt
     7501 tcttaaaaat gaaattctgt ctccaaatga ttccgggagg cggatatttg ctgttctctt
     7561 atttgtattc tcatccatat tttcacccat tcaactttcc tgattacagt tttacagttt
     7621 ggctttactc aacatttatt cagcattaat attgcagttg tgatcataat tctcacaact
     7681 atacaaggtt aggtttatct gataaaacgg cgcgtcgtct tgtttaagat actaacagca
     7741 tatctggaat ctgtgtgcat ttacaagcaa ccgtcagttg ttttttcgat tttttcgata
     7801 attcaaccat tggttgtttc cgtttcatca cttattatat caaaggaatg gattaataga
     7861 aagaatatca agcagattgc cgttcaatat atgcaataca catttaaaaa aacagcagac
     7921 ggatgctcac catccatctg ccgtctcttc tgtttcccca cacaatcctc tcacaaactg
     7981 ctcctgtgtt ataatccctt ccccaagctc accggaactt ttcatgaaca tctcagctct
     8041 gcgccggtcc agataaaatt cccaatacgg catccggttg tgcgcagaat ttgcaatact
     8101 ccttatctgc caataaacat catcctttgg atcttttgca tcgcctgtat cccacaccgg
     8161 aatccctgcc ccgctttcgt ataatttccc ggcgaaattc tgcagtacct cttccagtgc
     8221 ctgaactgtc tcttttggat attccgctgc cctatttaca acaaagatat cgctgatccc
     8281 tcccagcacc tctccctggc tgtgcgtgcc gggaaacaag actgcagaca gcttcccatg
     8341 taagggattg ttctccctca ctatatttcc ggtgaaatcg ctttttgcca agtacatagg
     8401 tatcttactc agataaaaat cattctccac atcctgcgtg cttcttgaaa ataaaggttc
     8461 tccaaaagcc cccatatccc ggagccggca aaacttatcc acgccggcgg caaaagcggc
     8521 ggtctcctcc tctgttcctt tctgactgag tacctttgcg caggtttcac ttcccgcctc
     8581 acttacgcat atactctcca gatagagcct gaatccggta tccgcgtcac cggagcaggc
     8641 aaagggtgtg atatccctgg caagaaattc ccggcatacc tccagcaatt cttcccaatc
     8701 tgtaggaacc cggcacccgt acgcctcaaa catatcctcg tttacaaata aaacagctat
     8761 gctttcagaa aatcccagac catagatccc gccttcataa gtcatactct ccaatacatc
     8821 cgcatgaagc ctgctgcccg tgtcatctga caaaaattca ttcattttta acagctttcc
     8881 ggaactgact gccccccgca gataactgtc cccaaaacaa aaataaatgt ccggtgtatc
     8941 attggaagca atggccgagg gcagtttttc tctgtaaagt tccatctctg tcccttctgc
     9001 ctgaatctgt atcctgtcat gtgtctcgtt atactcctcc actgcctcaa ggaacgattt
     9061 tttatatgcc tccccttcat tctcccaggg atgccacagc cgtagattta tcatcgtctg
     9121 ttcatctcta ctgctgtcgt tctccagctt tggaaaaaac ctgaggaaga acacggttat
     9181 cactgccaat agaaataaaa accccaataa aaaaattttc tgccatcttt ccacctgcta
     9241 tcacccatgt tgtcctttac tgaactcaga ttttcagtat ctttttaata tattccgccg
     9301 ctgcctttcc cagattgctg tgccccttac tgctcagatg gatacagtct ttcacggata
     9361 cctccgcagc gctgcccgca tccattagat atactccttc tatatccttt aaagcggtct
     9421 cataggctcc atacagagct ttacttttcc tcacagattc ctcatcatac ataccgtaaa
     9481 aatcagaccc tgcaatctca tcccgcaccg gtggcggcgc gatcaccagt acctggggtg
     9541 tttttccaac ccagtatgcc tcccggttac gagccattct taccaggttt accatacctg
     9601 ctgcaatctc tttcacactg ggcgtaaata tatggcggac atcatttgtc cccagcatga
     9661 gcaccaccag atccaatggc tgatgactct gcagactgca gtttaaaaac tttcttccat
     9721 ttcggtcagg tgaggtgggg tcgtcaaaca tgacagagcg cccacaaagc ccctcctcaa
     9781 tgatctttgc ctttccctcc agacacttct gtaaaactcc ggtccatctc acatcatctt
     9841 cataccggaa gttttccccg tcaggttcag gattatgccc ccatgtatta gaatcgccat
     9901 aacacaatat tcgtttcata cctctttatc ctttcacagc tcctaatgtc attccttcta
     9961 taaatttatc acttgcaaaa ataaatgcaa taagcagagg gataaaactt atcatagacg
    10021 ctgccattat ggttcccgtc agcgttccgt ttaaatcctt catggaggca attcccagag
    10081 gaagtgtctt catcatagtc tcattcacgg tgatcagagg ccaggtcagg cttccccact
    10141 gctgcgtaaa attgaagatt gccagaaggc tcaactgcgg taccgttatg ggcagcacga
    10201 tcttaaaaaa tgttccataa ttactgcacc cgtctatctt tgccgcctcc agaagagaat
    10261 ccggaatatc cttcataaac tgtgtcatca tatagactcc gaaagcactt gccacacccg
    10321 ggaagatcag ggacttatat gtattaaccc atcccagctt agagacaatg agaaacagcg
    10381 ggatcaatgt ggtcacactg ggaatgatct gcgtggccac aaccacatta aacaaaaccc
    10441 gggatccggg aaactttctc tttgcaaacg cgtacccggc catggatgcc accagcacta
    10501 ccagcaccgt attactgccc gcaacaaata tactgttcag catccagcgc agataagccc
    10561 cgccctgcat tttcaatacc tctgtataat tactcagaga gcctccgctg ggccagaact
    10621 tcggcggata actgattata gcattagtat ccagcataga ggatacaata agctgccaga
    10681 atggaaacgc gatgatgacc accagcaaaa gcagcataaa cgctttcaga aaggaaaaaa
    10741 ctcttttctt aaccctgtat ctgttcatac tttttccccc ttctcttgct cttatccctt
    10801 tcacctaaaa gcagattttc aagtccatat atgagcagga tcacaagcag aaatacaagc
    10861 gaggctgctg ccccgaatcc caccctgtaa tatttaaagc tgtactggta tatctcgtaa
    10921 atgacagtct gtgtggctcc cagcggtcct ccgtttgtga gcatatacac agattcaaat
    10981 atctggaact gccaaatcgt attcatagtc acgcacagaa tgatagcgtt tctgataagg
    11041 ggaagaacca catagatagt ctcctgcacc acattagccc catcgatcct ggaggattcc
    11101 agacaatccg caggaagtga acgcattgcc gacatataaa caaagacaaa aaaggttccg
    11161 cccttccaaa gttccagtat cataactgcc atttttgcac tgaacctgcc gttcagccaa
    11221 ctgataggct tcatgcccaa cacctgaaac aacatattca gaggaccgtt atttgataaa
    11281 atataagaga tcagaacact ggcaaccacc atggatatca gcatgggaag aaaataaaca
    11341 acttcacacg catggctcag ccttgttttt ttcttgatca gaagtgcaaa aaatattcca
    11401 aggaactggc tcaccggaac ttctatgagc atataaataa aggtgttttt aaacgcgttc
    11461 tgaaaatccg gtgtctgcag aacatcctta aagttcttca gccctaccca ttcaaactgt
    11521 gcctgcagaa agttaccgtc atgcaggctg agataaaata catatcctat aggtactatt
    11581 gtaaaaacaa tgaagaatac cgcaaacggc agtaaaaagc tataggacac agcatattct
    11641 ttccattttc ttttattcat aataaataca ccatcctccc aaacggcaga ggggcctttg
    11701 caatgcagat tcaatccctc actgcaaaaa cccctctttc tatccggcct tttaaagacc
    11761 aaaactcagt tccggaactt attctccgct gatcgccttc atggaatcat acatggcctg
    11821 gatggcatct gcaggtgatt tctcacccct tgcaacattt tcgtacatga tcttcagatt
    11881 ctgaagcatt gcattggcat aatcagaagc cgggcttacc tgaagcttct tgatcccttc
    11941 tgccgcaaca gccataattt catccccttc atacatcatg tcattggtag caagctgcgg
    12001 tgagaagaaa ccgacttctg agagatatat tttctcaacc tcaggtcttg taatgtattc
    12061 aacaaatttc catgcctcat ccggatattt tgtctggctg gagatggaga gcataccaat
    12121 gttggcaaaa ttccatt
//
