LOCUS       c00017_gnlPro..        16368 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FOBFLDAG_17.
ACCESSION   c00017_gnlPro..
VERSION     c00017_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-08 00:06:38
            Original ID  :: gnl|Prokka|FOBFLDAG_17
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 26749
            Orig. end    :: 43117
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16368
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[36749:39741]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12992
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16368
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16368
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(812..1786)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_22"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.6e-40,
                     bitscore: 129.7, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVKVSVILPVYNASDYLHQCMDSIVGQTLKDIEIICVDDGSTDN
                     SLDILKEYEQKDKRVKVIQQKNAGAGAARNNGLSIATGEYLSFLDSDDFFEFDMLEKAY
                     EKAKGSNAQIVVFRSDQYREDLKEFVKVKWTLHEKQLPPYRPMNFRSFTGNVFRVFVGW
                     AWDKLFERKFVEENHLKFQELRTSNDMLFVFSAIAFAQRIEIEDVILAHQRRNNPKSLS
                     NTREKSWECFRMALNALKDALTAHGNFWEFEQDYINYALHFSLWNLDTITGPNKERLYN
                     KLKNEWFAEFGIDSLPAERFYDKKEYAKYLKIKSGDFNAYCEQ"
     CDS             complement(1797..2945)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_23"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-33,
                     bitscore: 107.3, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKVSIIIPTYNVEMYLVECMESVVNQTLKDIEIICINDGSTDGS
                     LEILKSYAQKDDRIVLVDKENGGYGIGMNIGLDKATGEYIGIVEPDDFIPLNMYSDLYE
                     KAVENDLDFIKADFYRFKRDSETEDMELVYNHLSPNKEDYNIVFNPSETPKAIRYIMNT
                     WSGIYKRSFIEEFHIRHNETPGASFQDNGFWFQTFAYAKRGMIIDKPYYMNRRDNPNSS
                     VHNKEKVYCMNVEYDHIRELLVRDKEVWERFRSMYWLKKYNNYMGTIKRIGEEYKREYV
                     HRFSDEFKRGLELGELDESVFTKISWSNIQFITKDPNGFYMKKVATPVKVRRLQKKVEK
                     LEKQNAKLKNDIKIIKGSRSYRLGWFLLTIPRKIKAIFKGNK"
     CDS             complement(2960..4066)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_8"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_24"
                     /sec_met_domain="NAD_binding_8 (E-value: 1.7e-21, bitscore:
                     67.3, seeds: 167, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKYDYLIVGAGLFGAVFAHEMTKEGKKCLVIDKRDHIAGNIYCE
                     NVEGINVHKYGAHIFHTSDKVVWEYINQFAEFNNYINSPVARYKDELYNLPFNMNTFSK
                     MFGIKTPAEAKAKIQEEIEELGITEPKNLEEQALSLAGRSVYEKLVKGYTEKQWGRDCK
                     DLPAFIIKRLPLRFIYDNNYFNDRFQGIPMGGYTAIVEKMLEGSDVLLNTDYYEFRKEN
                     ADIAEKTVYTGMLDKYFDYKYGVLEYRSVRFETETLDMDNYQGNAVVNYTEREVPYTRI
                     IEHKHFEYGTQPKTVISREYPSEWKLGEEPYYPVNNEKNEEVAGKYRELAEKEKNVIFG
                     GRLGEYRYYDMDKVIAAALKAVEKEKNN"
     CDS             4260..5498
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_25"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 2.4e-34,
                     bitscore: 109.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 3.2e-30, bitscore:
                     95.3, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSYKIAIAGTGYVGLSNAILLSQHNEVYAVDIIEEKVNLINSGK
                     SPIVDREIQEYLATKDLNLTATTDAKLAYENADFVIISTPTNYDPKMNYFDTSSVEAVI
                     KLVLEYNPNATMIIKSTVPVGYTLSVREKFNTKNIIFSPEFLREGRALYDNLYPSRIIV
                     GAPLEDERLVQAAHTFAGLLKEGAIKEDIPVLFTNPTEAEAVKLFANTYLALRVSFFNE
                     LDSYAEVHGLNTKQIIDGVGLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYKDVPENL
                     IEAIVKSNSTRKDFIADRILEKAGYYHGTAGRDGTPGNQVTIGVYRLTMKSNSDNFRQS
                     SIQGVMKRLKAKGAEVIIYEPTLADDTFFGSKVEKDFDAFKANCNVIIANRFSDELADV
                     EDKVYTRDLFRRD"
     CDS             complement(6203..7555)
                     /locus_tag="ctg17_26"
                     /transl_table=11
                     /translation="LSYTWYEVFWFFLLYSFAGWVIGTSGAALKEKKFIDVGFLFGPWC
                     PSYGFGAVGFALFLPELKDQPVFLFAGGVILSFIITSFTGVTLERIFHQKWKDYSRRRF
                     NFGGYVNLPYTVVWGAAALLCIWIVNPFLSKIIGILPYGLGKVILIIAYVIIIIDFIGT
                     VSGILSVHIRLARLGKLVLVEEVADNLQKAADYMGNGLTGWVLKHLEKSHEGLEIKEII
                     RSKLQRREKAQEMTGVFAAGCGFYKLFWLFFLGSFLGDITETIFCWWKMGTITSRSSVV
                     YGPFSLVWGIGCFFLTYMLYQYRDRSDSFIFIFGTVLGGAYEYICSVVLELVFGTVFWD
                     YSKIPFNLGGRINLLYCFFWGIAAVVWMKILYPKLSGFIEKIPKKIGVPLTWFLVVFMV
                     FDMAISGLALNRYHERHQSAKTPETAITKILDTRFPDTRMERIYPSAKHVR"
     CDS             7620..8381
                     /locus_tag="ctg17_27"
                     /transl_table=11
                     /translation="VNPPNAILHELLNLAEIMLTNGAEVSRVEETLNRMGHAYGATQMN
                     VFAITSSIVVTMVFEEGEEYTQTRRITTPVGTDFFKLEQANALSRRCCSSPLSLADLKY
                     EINKISKISPAPYTIYLGSMLGAGGFSVFFGGTILDGAIAVIFAFLLCFLQRHLNSICS
                     NTLILQFFCSLFVGSGICVAAHFFPVIHADKVMIGDIMLLIPGILMTNSIRDILIGDTI
                     SGVMRLVESLLWAGALACGFMCAIWFVGGVL"
     CDS             8378..8812
                     /locus_tag="ctg17_28"
                     /transl_table=11
                     /translation="MILQFFAAFIGAAGFGFLFHLQFKHIFPAALGGVLTWVIYVIATI
                     WGFDVFISSLFASAFAAIYSEVIAKIRKAPTTLFLIISVVVLIPGGSLYYTMSYAVQKK
                     WAEAAAYGSQTLQCALGLAIGMSLIWIFHDMARKVYYLIH"
     CDS             10001..12253
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_29"
                     /sec_met_domain="Gly_radical (E-value: 1.9e-41, bitscore:
                     132.0, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 8.9e-267, bitscore:
                     877.2, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLQKEQWQGFNGRIWREEINLREFIQDNYTPYDGDASFLEGPTEA
                     TDTLWGELQKLQKAEREKGGVLDMDTDIVSSLTSHKPGYISESLKEKEQIVGLQTDKPL
                     KRAFMPFGGIRTAEEACTTYGYTPNPEFHKIFTDYHKTHNQAVFDSYTPEMKKARHNKI
                     ITGLPDTYGRGRIVGDYRRVALYGIDLLVADKQKDFANCGDGTMTDDVIRLREEISMQI
                     KALKDMKVMAESYGYDISEPASNAKEAVQWTYFGYLAAIKTQNGAAMSIGRIATFLDIY
                     IKRDMDKGILTEKEAQELIDHMTMKFRMVKFGRIPAYNQLFSGDPVWATLEVGGLGQDG
                     RSMVTKTDYRFLHTLENMGPSPEPNLTVLYSERLPKAFRDYAAHISITTSSIQYENDDV
                     MRPVWGDDYSICCCVSATQTGKEMQFFGARANLAKCLLYAINGGVDEKTGQQVGPEYKP
                     ITSEYLDYDEVMHKYDIMMDWLAGLYVNTLNLIQYMHDKYYYEYALMALIDTNVRRTFA
                     TGIAGFSHVVDSLSAIKYAKVKTVRNEEGLVVDYETTGDFPKYGNDDDRADDIAVWLLQ
                     TFMKKLEKFHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQ
                     NGLLASLNSVAKLPYEWALDGISNTQTINPDALGHSEEERIGNLVNVMDGYFAQGAHHL
                     NVNVFGVEKLIDAMEHPEKEEYANFTIRVSGYAVKFISLTKEQQLDVIARTCHDRM"
     CDS             12225..12992
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.1;
                     E-value: 1.1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_30"
                     /sec_met_domain="Radical_SAM (E-value: 2.1e-32, bitscore:
                     103.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPEHAMTECNKNAMALVHSTESFGSVDGPGVRFIVFLQGCPLRCQ
                     FCHNPDTWKMTEENGAVWRSADELLNQALRYRTYWKNSGGITVSGGEPLLQIDFMLEFF
                     KKAKEKGIHTVIDTAGGPFTREEPFFSKFQELMKYTDLLLVDIKHIDNKYHKVLTGRSN
                     ENILDMIRYLSDIKKPIWIRHVLVPERSDKDEYLTRLADFIHSLDNVEKVEILPYHTMG
                     IYKWKELGLEYPLEGIDPPTKERVENAKKILAI"
     CDS             complement(13172..16366)
                     /locus_tag="ctg17_31"
                     /transl_table=11
                     /translation="GKLMKNNHNLLMKMKNLEKFSGAIKRCVAIAMASMLFATTGFSLD
                     THPVKAQEVSSSADKIEIPEISKDAFKKYKKISGIGANTILGADFTYYQQCLEWGKSYK
                     NYMSQSVDNIFDYVKSQGINTISLKVAVNPTGENAYLSLENAIKTLKAVKASNTNLKTN
                     LVLLYSDEITYAGTQNLPADWEKAEKEEQSVTRVESAKTYTRETIAKLKQANVLPDIVT
                     IGNEVNWNFLGITDGEGWEGWKAMGDISALLKKEGVKNAVSIAAQPDAASVKYIVQKLG
                     YASVDYDYIGVNVYPDNNTNSYIKSLKNEVESCAPDKQLIVSNVEYERVNEANTANVYT
                     QADSIYNLLEATIDEKNAGGLIYNEAAYVGSWKSFFDDEGDAQVSMAIFAYAQGNETDT
                     SRDPYKYGDDTGLKQQKVTIKKVKNMSDSTIRGIDISSYTALKKAGVKYYDNEGKEASL
                     LKVLSDNGVNYIRIRIWNDPYNEKGETYGGGSNDVKAGLEIAKEAAKYNIKVLLGFHYS
                     DFWADPAVQLLPKAWEKDRNNQEKMCSNVYEFTKETLEQFKDAGADIGMVQVGNEISQG
                     MMGIMHRTKANVWQEEEKSVLIDSYLNAGARAVRECVPDALVAIHLDTLNLSIYKDAMN
                     AWERDKVDYDVLGSSSYAFWAGKNMLGNVRKAGNYVASRGKLFAVLETSWLNSQKDADG
                     TVNMVNNTKDAVYKVGPQGQADMLSDLYDAILSNDNGLGAFYWEGAWIPVKAGWVNWKY
                     NKEMANEFGTGWATENAGGYYPKSKLYYNGNPVWGGDSWDNQTLFDDKGYPLDSLRFYK
                     DAVSSNEKYSRVVIALCDKENNVLEYRVVKVISGKSMTYTLPEIKGYTKEKDTIKILGT
                     NDKISKVSVVYNKDIKKQTITVKKASYTIPYGTKFNLKNEVKAVGSLTFTSNNTNIVSV
                     EKQGKKLVVKKPGKVKIKITAGATADYKQTSRIVTIYAVPKKQTIKKVSTAKRKVKVNI
                     KKDVKATGYQIVAAKNSRFSKGKKVLTKKGTRQVTYTITKLNSRKIYYVKARAYKTIGN
                     KKYFGPWSKVKKIRIK"
ORIGIN
        1 tctaatatct gcatcaagcc tctgaccact tctaaataag attcaaaacg tgttttattt
       61 tcagaagtag tcattgttga attagccctg acacgtctta aatataaatt atctctgaca
      121 catcttgcct tacctgcctt aagtgtaact ttcacagtat ataaattatc ttcaaaatat
      181 cgttccatgc caaacttgat attattatcc agcagaaact ggcgacatgt gaactgcaaa
      241 ccgactgaca tctttatatc tcctgcattc tccatctgga tatacagatt ccttccatca
      301 taaataccat catattcttt atgtctgtgg tataatgtaa gaaattgagg aaatgcttcc
      361 tcaatttctt ttgtttcgta gaaactatct gcctcaaaat acacaacatc cagattgtct
      421 gcttctgcat actgatacag tgtctccaaa caattctcct taagtaaatc atcgctatcc
      481 atatagtaga tatattttcc ctgagcacac tgaacacctg tatttctctg gtacgcaact
      541 ccgtgattct cacttgaaat cacccgtata tttggatacg actgttgata tctcttcaat
      601 atctctaatg taccatccgt tgaaccgtca tttaaacaaa taatttcata atctttaaag
      661 ctctgattca atacagactt taatgtttct tctacatatt gttctgtatt ataacaaggc
      721 attattaccg aaattccata ctctttttta tcagtactca ttgaggtctc cttcctgtat
      781 atctacttac aatgtctatt cctcttaatg tctactgctc acaataagca ttaaaatccc
      841 ctgattttat cttaagatat ttggcatatt ctttcttatc ataaaatctt tctgctggaa
      901 gagagtctat tccaaattca gcaaaccact cattttttaa tttattatat aagcgctctt
      961 tatttggacc tgttatcgta tctaaattcc ataaactgaa atgtaatgca tagttaatat
     1021 aatcctgctc gaactcccag aagtttccat gtgctgtcaa agcatctttt aatgcattca
     1081 aagccatgcg gaaacactcc caggattttt ctctcgtatt ggacaaagac tttggattat
     1141 ttcgacgctg atgcgctaaa ataacatctt caatctcaat tctttgtgca aacgcaattg
     1201 ctgaaaatac aaataacata tcatttgacg ttctaagttc ctgaaacttt aaatgattct
     1261 cctcaacaaa cttacgctca aacagtttgt cccatgccca tcctacgaac actctaaata
     1321 cattgcctgt aaaagagcgg aaattcatcg gacgatatgg aggaagttgc ttttcatgta
     1381 atgtccattt tacctttaca aattccttca aatcttctct atactgatcc gaacgaaata
     1441 ctacaatctg tgcattagaa ccttttgctt tttcataagc cttttccagc atatcaaact
     1501 caaagaaatc atcagaatca agaaaagaaa gatactcacc agtcgcaatg gataatccat
     1561 tgtttctggc tgctcccgct ccggcattct tttgctgaat tactttgaca cgcttatctt
     1621 tttgctcata ttcttttaaa atatctaaag aattatccgt ggaaccatcg tctacacaga
     1681 taatctcgat atcctttaaa gtctggccta caatgctgtc catacattga tgaagataat
     1741 cagacgcatt atagaccggc agtataacag atacttttac gctcatagct tctcctttat
     1801 ttattgccct taaaaatagc cttaatcttt cttggaattg ttaacaggaa ccagccaagt
     1861 ctatatgatc tggaaccttt gataatctta atatcattct taagctttgc attctgcttc
     1921 tctaactttt ctactttttt ctgaagtctt cttactttta ccggcgtagc aactttcttc
     1981 atatagaaac cgttcggatc ttttgtaata aactgaatat tagaccagct aatctttgta
     2041 aatacggatt cgtctaactc tcctaattca agtccccgct taaactcatc actgaaacga
     2101 tgaacatatt ctctcttata ttcttcacca atacgcttga tcgttcccat ataattgtta
     2161 tacttcttta accagtacat tgaacggaaa cgctcccata cctctttatc tctcaccagc
     2221 aactctctga tatgatcata ctcaacattc atgcagtata ccttttcttt gttatgaacg
     2281 gaagaattcg gattatctct tcgattcata tagtatggct tatcaatgat cattccacgc
     2341 tttgcatagg caaatgtctg gaaccagaat ccattatcct ggaaagatgc accaggagtt
     2401 tcgttatgac gaatatggaa ttcctcaata aagcttctct tataaattcc gctccaggta
     2461 ttcataatat aacggattgc tttcggtgtt tcacttggat tgaacacgat attataatct
     2521 tccttatttg gtgataaatg attataaact aattccatat cctctgtttc actgtctcgt
     2581 ttaaaacgat agaaatctgc cttaataaag tctaaatcat tctcaacagc tttttcatat
     2641 aaatcactat acatatttaa cgggataaaa tcatctggtt ctacaattcc gatatattct
     2701 ccagtcgctt tatctaaacc gatattcatt ccgattccat aaccaccatt ctctttatca
     2761 acaagaacga ttctgtcatc cttttgcgca taactcttta agatttctaa agagccatcg
     2821 gttgaaccat cgttaataca gataatttca atatctttta atgtctggtt tacaacactc
     2881 tccatacatt ctacaagata catctccacg ttataagtag gtataataat agatactttt
     2941 gccatttcct cactcctaat taattattct tttctttctc tactgctttt aatgccgctg
     3001 caattacctt gtccatatca taataacgat attcgccaag acgacctccg aaaataacat
     3061 tcttctcttt ttctgctaat tcacggtact ttccagcaac ttcttcattc ttctcattat
     3121 tcaccggata gtatggttcc tcacctaact tccattcact aggatactct ctggaaataa
     3181 cggttttagg ctgtgttcca tattcaaaat gcttatgctc gataatacgt gtataaggaa
     3241 cttcacgctc tgtatagttt actacagcat taccctgata attgtccata tctaaagtct
     3301 ctgtctcaaa acgaacgctt ctatactcta atacgccata tttgtaatca aaatatttat
     3361 ctaacattcc tgtatataca gttttttctg cgatatccgc attctctttt ctgaattcat
     3421 aataatctgt gttcagtaat acgtcagaac cttctaacat cttctctaca atcgcagtat
     3481 atcctcccat aggaattccc tgaaaacggt cattaaagta gttattatca taaataaaac
     3541 gaagtggaag tctcttgata ataaatgcag gaagatcctt acagtcacgt ccccactgtt
     3601 tctctgtata accctttact aacttctcat atacagaacg gccagctaaa gaaagagcct
     3661 gttcttctaa gttctttggt tctgtgattc ctaattcttc aatttcttcc tgaatttttg
     3721 cttttgcttc tgccggtgtc ttaataccaa acatcttgct aaatgtattc atattaaatg
     3781 gtaagttata aagttcatct ttatatcttg ctaccggaga gttaatgtaa ttattaaact
     3841 ctgcaaactg attaatgtat tcccaaacta ctttatcaga tgtatggaaa atatgagcac
     3901 catacttatg cacattaatt ccctctacat tctcacagta aatattacct gctatgtgat
     3961 ctcttttatc aattacaaga catttttttc cttcttttgt catttcatga gcgaaaacag
     4021 caccaaaaag tcctgctcct acaatcaaat aatcatattt tttcatgatt tctcctttta
     4081 catttttctc caaaaaatat tgttctgtaa tatatccgta atattttaac atgatataac
     4141 atttttttca attgataaac ctcttaaata atcttatgat gtacattctt ttcttgactt
     4201 tttaacacac tctgtttaca attttactaa ataatgttca ataaaggagt gtattattaa
     4261 tgagttctta taaaatagcg attgccggaa ccggttatgt cggtctttcc aatgcaatcc
     4321 ttctttctca gcataacgaa gtttatgccg ttgatattat cgaagaaaaa gtaaatctga
     4381 tcaattccgg caagtcccct atcgtagaca gggagattca ggaatacctc gctacaaaag
     4441 acttaaatct cacagcaact actgatgcta aacttgcata tgagaatgca gattttgtta
     4501 tcatcagtac tcctactaac tatgacccta agatgaatta ctttgatact tcaagcgtag
     4561 aagctgttat caagttagtt cttgaataca atccaaacgc gactatgatt atcaaatcca
     4621 ctgttcctgt cggatatact ctttctgtaa gagaaaaatt caacacaaaa aatatcatct
     4681 tctccccaga atttttacgt gagggacgtg ctctttacga taatctctat ccttccagaa
     4741 ttattgttgg tgcaccatta gaagatgaac gtcttgtaca ggcagcacat acttttgccg
     4801 gtcttttaaa agagggagct atcaaagaag atattcctgt tttatttaca aaccctacag
     4861 aagctgaggc cgttaaatta tttgccaata cttatctcgc actccgcgta agtttcttta
     4921 acgaacttga cagctatgca gaagtacatg gcttaaatac aaagcagatt attgatggtg
     4981 ttggtttaga cccacgtatc ggcacacatt ataacaaccc atctttcggt tatggcggat
     5041 actgccttcc aaaagataca aaacagcttc ttgccaacta caaagatgtt cctgaaaact
     5101 taattgaagc gattgtaaaa tctaactcca caagaaaaga ttttatcgct gacagaatct
     5161 tagaaaaagc cggatattat cacggtactg ccggacgtga cggcactcct ggtaatcagg
     5221 ttaccatcgg tgtataccgc cttactatga agtccaactc cgataacttc cgccagtctt
     5281 ctattcaggg tgtcatgaag cgcctgaaag ctaaaggtgc agaagttatc atttatgaac
     5341 caactttggc tgatgatact ttctttggaa gcaaagttga aaaagatttt gacgctttca
     5401 aggcaaactg taatgttatt attgcaaatc gtttttccga tgaactcgct gatgtagagg
     5461 acaaagttta tacaagagac ctcttccgaa gagattaaat cctgatttgt gaggctacga
     5521 agcagacgaa ctccagaagc taaataaagc atatttgtga ctttagtcgc gacagtttga
     5581 atgttcgctt aaagcgctca catccaaacc ttgctccgag gccacaaata tgctttattt
     5641 agtttctgga gttctgtgtg ttggcaactc agaaaatcag ttggagggat ttggagaaga
     5701 aggttgaagg catagaaata tccagaaaat taaattctat aggattgata cataaactat
     5761 tatcatagta atacaataat ttatgggtag gttactactt tcttatgaac tggaaattta
     5821 aaactgttta tagctttatc tcttaaaaag tgagatgttt tcattgaaaa cgcgaaaaaa
     5881 aactacaaaa aaactgtaaa aaacaaataa atttttaaat caattccagt aatggtttaa
     5941 acgtcagttc tttagaattt taactcctcg gaatgccata accatctgac gcccctcaaa
     6001 tctctccaaa aataaattct gaatttactt aggcagccaa aacacagccc acagggaata
     6061 taatatccta tatttgtggc ctcggagcaa gtgttggata cgagcgaata gagcgagtat
     6121 tcaacatgcc gcaactaaag tcacaaatat aggatattat attccctgtg gacgtctcct
     6181 ttgctacgca aatcagaatt ccctacctca catgtttggc acttgggtat atccgttcca
     6241 ttcttgtgtc tggaaatctc gtatctaata ttttcgttat ggcggtttcg ggtgtctttg
     6301 cactttggtg tctttcgtga taacggttta atgcaagacc tgagattgcc atatcgaata
     6361 ccatgaatac aaccaagaac caggttaatg gtaccccgat tttctttggt atcttctcaa
     6421 taaatcctga tagtttcgga tataatattt tcatccagac tacggctgcg attccccaga
     6481 agaaacagta caataagttg attcttccac ccagattaaa tggaattttg ctgtaatccc
     6541 agaatacggt tccaaagaca agctctaata cgacactaca tatatattcg taagcaccgc
     6601 cgaggactgt tccgaatata aagatgaagc tgtcgcttct atcgcgatat tggtagagca
     6661 tataggtgag gaaaaaacag ccaattcccc agacaaggct aaatgggcca taaactacac
     6721 tgcttcggct tgtgatagtg cccatcttcc accagcaaaa gatagtttct gtaatatcgc
     6781 caagaaaaga gccaagaaag aacagccaga acagtttgta aaatccacat cctgctgcaa
     6841 atacaccagt catttcctgt gctttttctc gtctttgcag tttacttcgg atgatttcct
     6901 tgatttcgag accctcatgg cttttttcaa gatgttttaa cacccagcca gtcagaccat
     6961 ttcccatgta atctgcagct ttttgtaagt tatcagctac ttcttctaca aggactagtt
     7021 ttcctaatcg tgccaggcgg atatgtacac tcagaattcc tgaaacagtt ccgataaaat
     7081 caataatgat tattacatag gcaataatca aaatgacttt tcctaatcca tatggaagta
     7141 ttccaataat tttacttaaa aatggattta caatccaaat acacaacagt gccgccgcac
     7201 cccatactac cgtataaggt aagttaacat agccaccaaa gttaaatctc cgtctggaat
     7261 aatctttcca tttctgatgg aaaatacgtt ccagggtcac tcctgtaaaa gatgtgataa
     7321 taaatgaaag aatcactcct cctgcaaata aaaatacagg ctgatctttt aattctggta
     7381 aaaataatgc aaaaccaacg gctccaaatc cgtaggatgg acaccacggg ccaaataaaa
     7441 atcctacgtc aataaacttt ttttctttta atgctgctcc agaagttcct attacccatc
     7501 ctgcaaagga atataacaga aaaaaccaga acacttcata ccaggtatag ctcaaaattt
     7561 ttctcctttt tttgaatttg tgatatacta tatcatattt ttgtgaaagg agaaagtatg
     7621 tgaatccacc aaatgctatt ttacatgaat tactaaatct tgcggaaatt atgctgacca
     7681 acggtgccga ggtcagccgt gtggaagaaa cgctaaaccg aatggggcat gcctacggtg
     7741 ccacccagat gaatgtattt gcaatcactt caagtatcgt tgtcactatg gtctttgaag
     7801 aaggcgaaga atatacacaa acccgaagaa tcactacccc tgtcggtaca gatttcttta
     7861 aattagaaca ggcaaatgca ctcagcaggc gctgttgttc ttctcctctt tcccttgcag
     7921 atttgaaata tgagataaat aaaatttcaa aaatcagtcc tgctccttat accatttacc
     7981 tgggaagtat gcttggtgca ggtggctttt ctgtcttttt tggaggaaca attttagacg
     8041 gagccattgc cgttatcttt gcctttctcc tttgcttttt acaaaggcat ttaaactcta
     8101 tatgcagcaa cactttaatc ctgcagtttt tctgctccct ttttgtcggc tccggcattt
     8161 gtgtagctgc acatttcttt ccggtaattc atgcagacaa agttatgatc ggtgacatta
     8221 tgctgctgat tcctggaatc cttatgacaa actctatccg tgacatttta atcggtgaca
     8281 cgatttcagg cgtgatgcgt cttgtagaat cgcttctttg ggcgggagca cttgcctgtg
     8341 gatttatgtg cgctatctgg tttgttggag gtgtgttatg atattacaat tttttgcagc
     8401 ctttattgga gctgccggct tcggcttctt atttcatttg caatttaagc acattttccc
     8461 tgccgcatta ggtggtgtac tgacctgggt tatctatgtc atcgcaacta tctggggatt
     8521 tgatgttttc atttcttctc tatttgccag tgctttcgcc gcaatttact ccgaagtcat
     8581 cgcaaaaata agaaaagccc ctaccacctt atttttaatc atttccgttg tcgttctaat
     8641 tcccggcggc tctctctatt acacgatgag ttatgctgtt cagaaaaaat gggcagaagc
     8701 agcagcttac ggctcccaaa cattacagtg tgctttagga cttgccattg gaatgagcct
     8761 catctggata ttccacgata tggcaaggaa ggtttactat ttaattcatt aagagacaga
     8821 cgcccgggaa gagaaccgat accctatatt tgtgacttta gtcgctgcgg tttaaatgct
     8881 cgctttatgc gctcgcatct aaaccttgct ccgaggccac aaatataggg tatcggttct
     8941 cttcccgggc tgtctttggc tggattttgt ttgaattaaa tagtggttgt ggggatttgg
     9001 gggagagggt agaagttttc tgcttgctct taaaatattg tgaatagatg ttttgtattt
     9061 aaatagaaga ggtaatgaat tgatattgat aacaacagtc tgctttttat tctgaaatta
     9121 ttgaaatatt gctgagataa ccattaaaaa agctaaatca tccccctgtt cccagtcatt
     9181 cttgagtaag cagaagacat cagtttctgt ccccaaatcc cctccctctg tttaattcat
     9241 cttctccagc catagcacag aagccattgc ctccaataag gcatatttgt ggtctcggag
     9301 caagtgttgg atgcgagcgc atggagcgaa cattcaacgc gccgcgacta aaatcacaaa
     9361 tatgccttat tggaggcaat ggcttcgtct gtagttctct taatgaatta aatagtaacc
     9421 ccttgacatt ttgttctatt ttgtttatag ttaggatact tatacgactg acggaagtaa
     9481 gtggaatgaa ccacatgaag tataagactc ttatagccga ccgtctgggc aattcttgtc
     9541 tggatgctgg cttttttatt tctgataaga taatattcta tccaatatcc ctgataagaa
     9601 gtaactttaa atcgttatta agtcatgtgc taaagaagat gtttttccaa acatgctcta
     9661 aagagcgaaa aataaaatta tagttgtatg cttgtcatta ttgtacttat atcagtacat
     9721 ttgtacgatt tgataatatt ttatcaacgc tctaaaaccc tttattttaa aggctctaca
     9781 agcatttttg tgtatatgtt caaaaaaaag aacacataat atcaaaaaat tgtttgacga
     9841 ttgccaaaaa tcatgttaat aatgttgtta gatgattaaa acttaaataa gttaaaacta
     9901 atcatagtaa atcatctgaa caattttgtt gattttttag caaacatatt tcaaaacctt
     9961 gacttaagga tttttttaac aaacagggag gtcaattaag gtgttacaaa aagaacaatg
    10021 gcagggattt aatggacgaa tctggagaga agaaattaat ttaagagagt tcatccagga
    10081 taactacact ccatatgatg gagatgcttc tttcctcgaa ggtcctaccg aagctactga
    10141 cacactgtgg ggcgaactgc agaagctgca gaaagcagag cgtgaaaagg gtggtgttct
    10201 tgatatggat actgatatcg tatcaagcct tacttcccat aaaccgggtt acatttctga
    10261 gtctttaaaa gagaaagaac agatcgtagg tcttcagaca gataaacctt taaaacgtgc
    10321 atttatgcca tttggtggta tccgtactgc tgaagaagct tgtacaactt atggttacac
    10381 accaaatcca gaattccaca agatttttac agattatcat aagacacata accaggcagt
    10441 atttgattct tatactcctg aaatgaagaa agctcgtcac aataagatca ttactggtct
    10501 tccagatact tacggacgtg gacgtatcgt tggtgactac cgtcgtgtag ctctttacgg
    10561 tattgacctg ttagttgctg acaagcaaaa agatttcgca aactgcggtg acggaacaat
    10621 gacagatgac gttatccgtt taagagaaga aatctccatg cagattaaag cattaaaaga
    10681 tatgaaagtt atggctgaaa gctatggcta tgatatttcc gaacctgctt ctaacgcaaa
    10741 ggaagctgtt caatggacgt atttcggata ccttgcagca atcaagacac agaacggtgc
    10801 tgctatgagt atcggacgta tcgctacttt ccttgacatt tatatcaaac gtgatatgga
    10861 taagggaatc cttacagaga aagaagcgca ggaattaatc gaccatatga ctatgaagtt
    10921 ccgtatggtt aagttcggac gtatcccagc ttacaaccag ctcttctccg gtgaccctgt
    10981 atgggcaaca cttgaagttg gcggacttgg acaggacggt cgttccatgg ttacaaaaac
    11041 tgactaccgt ttcctccaca cattagaaaa tatgggacca tccccagagc caaacctcac
    11101 agtactttac tctgagcgtc ttccaaaagc atttagagat tacgcagctc atatttctat
    11161 tacaacaagt tcaatccagt atgaaaatga tgatgtaatg cgtccagtat ggggcgatga
    11221 ttactccatc tgctgctgtg tttctgctac acagactggt aaggaaatgc agttcttcgg
    11281 tgctcgcgct aaccttgcaa aatgtctcct ttacgctatc aatggtggtg tggatgaaaa
    11341 gaccggacag caggttggac cggaatataa accgattact tccgaatatc ttgactatga
    11401 tgaagtaatg cacaaatatg atatcatgat ggactggtta gcaggtttat atgtaaatac
    11461 attaaatctc atccagtaca tgcatgacaa atattactat gaatatgctt tgatggcctt
    11521 aatcgataca aatgtacgtc gtacattcgc tacaggtatc gcaggattct cacacgtagt
    11581 agactcctta agtgctatca aatatgcaaa ggttaagaca gttcgtaacg aagaaggact
    11641 cgttgtagat tatgaaacaa ctggcgactt ccctaaatac ggaaatgatg acgaccgcgc
    11701 cgatgatatc gctgtatggt tacttcagac attcatgaag aaactggaga agttccatac
    11761 ttatcgtgat tctgaaccta caacttctat ccttactatc acatctaacg tagtatatgg
    11821 taaggcaaca ggttcccttc cagatggaag aaaagccggt gaaccacttt ccccaggagc
    11881 aaacccaagt tatggtgcag agcagaacgg tctcttagct tccttaaact ctgtagctaa
    11941 acttccttat gaatgggcat tagatggtat ttccaatacg cagacaatca accctgatgc
    12001 actcggtcat tccgaagaag aacgtattgg taacttagta aatgttatgg acggctactt
    12061 cgcacagggt gctcaccacc taaacgtaaa tgtatttggt gttgagaaac tgattgatgc
    12121 tatggaacat ccggaaaaag aagaatacgc aaactttacg atccgtgttt caggttatgc
    12181 agttaaattc atctctctga caaaagaaca gcagttagat gtaattgcca gaacatgcca
    12241 tgacagaatg taataaaaat gcgatggctc ttgttcattc tacggagagt tttggttcgg
    12301 tggatgggcc gggagttcgt tttattgttt ttttacaggg ttgtcctttg cgatgtcagt
    12361 tctgtcacaa tccagataca tggaagatga cagaggaaaa tggtgcggtg tggagaagtg
    12421 cggatgagct gttaaatcag gcactccgtt atcgtactta ctggaaaaat agcggcggta
    12481 ttaccgtaag tggtggtgag cctcttttac agattgattt tatgctagag ttttttaaaa
    12541 aggcaaaaga aaaaggaatc cacactgtta ttgatactgc tggaggacct tttacaagag
    12601 aggaaccttt cttttctaaa tttcaggaat tgatgaaata tacagacctg ttattagtgg
    12661 atatcaaaca cattgataac aaataccaca aagttttaac tggtcgtagc aatgagaata
    12721 ttcttgatat gattcgctat ctttccgata tcaaaaaacc gatttggatt cgccatgtcc
    12781 ttgtcccgga acgaagcgat aaagatgaat atttgactag attagctgat ttcattcact
    12841 ctcttgataa tgtggaaaag gtggaaatcc tgccttatca tacgatgggt atttataaat
    12901 ggaaagaact tggattagaa tatcctttag aaggaattga ccctccaacg aaagaacgag
    12961 tggagaacgc caagaaaatt cttgctattt gatttgccga caaacagaat cctaaaaccc
    13021 cccatatttg tgactttgaa gatagattgc gttgaatact tattcatatt caatctatcc
    13081 ttgaagtcac aatatggggt gctctttaga tataaacttc agttaaaatt cgctcaaatt
    13141 aaattctaat ttttcaaatg atctatggaa tttactttat tcttattttc tttactttgc
    13201 tccatggacc aaaatatttc ttattgccta ttgttttata agcacgtgcc tttacatagt
    13261 aaattttcct agaatttaat tttgttattg tatatgttac ctgtcttgtt cctttctttg
    13321 ttaatacctt cttgcccttg ctaaatcttg agttcttagc tgcaacaatc tgatatcctg
    13381 tagcttttac atctttcttt atattcactt ttacttttct cttagctgta gaaacctttt
    13441 tgatggtctg ctttttcgga actgcataaa tagtaactat tctactggtc tgtttataat
    13501 ctgctgttgc accggctgtt attttaatct ttacttttcc tggcttcttt acaacaagtt
    13561 ttttaccctg cttttcaaca gaaacaatat tcgtattatt tgaagtaaat gttaaacttc
    13621 caactgcttt tacttcgttc ttaagattaa actttgttcc ataaggaatc gtataggatg
    13681 cttttttcac agtaattgtc tgttttttta tatccttatt ataaactaca gataccttag
    13741 atatcttatc atttgttcct aaaattttaa ttgtatcttt ttctttcgta tatcctttaa
    13801 tttccggtaa tgtataagtc atactctttc ctgaaataac ttttactacc ctgtattcaa
    13861 gtacattatt ttccttatca cataatgcaa taaccactct ggaatatttc tcgttagatg
    13921 acactgcatc tttatagaag cgaagagaat ctaatgggta tcctttatca tcaaaaagcg
    13981 tttgattatc ccaagaatct cctccccaaa caggattccc attataatac aatttactct
    14041 ttggatagta tcctcctgca ttttctgtcg cccatcctgt tccaaattca ttggccattt
    14101 ctttgttata tttccaattc acccaaccag ctttgacagg tatccatgcc ccttcccaat
    14161 aaaaagcacc caatccatta tcatttgata aaattgcatc atataaatct gacaacatat
    14221 ctgcctgtcc ctgaggacca actttataaa ctgcatcttt agtattatta accatattta
    14281 cagtaccatc tgcatctttc tgagagttaa gccatgatgt ctccaatact gcaaataatt
    14341 tacctctgga tgcaacataa tttccagctt tccgaacatt cccaagcata ttttttccag
    14401 cccaaaaggc atagctagaa gatcctaaaa catcataatc cactttatct ctttcccatg
    14461 cattcatagc atctttatat atacttaaat taagagtatc taaatgtatc gcaaccaaag
    14521 catctggcac acattctctt actgccctgg cacctgcatt taaataactg tcaataagca
    14581 cagacttttc ttcttcctgc cagacattgg ctttagttct atgcataatc cccatcattc
    14641 cctgagatat ttcatttcca acttgtacca taccaatgtc agcaccagca tctttaaatt
    14701 gttctaaggt ttctttagta aattcatata cattagaaca cattttttcc tgattatttc
    14761 tatctttttc ccatgctttt ggaagcaact gtactgctgg atctgcccaa aaatcagaat
    14821 aatggaatcc caataaaact ttaatattat atttggctgc ctctttcgct atttctaacc
    14881 cagccttaac atcattggat ccaccaccat aagtctctcc tttttcatta tacggatcat
    14941 tccatatacg aatacgaatg taatttacac cattatcact taaaactttt agtaatgagg
    15001 cttcttttcc ttcattatca taatatttta ccccagcctt ttttaaagca gtatacgatg
    15061 aaatgtctat gcctcgaata gtagaatctg acatattctt cactttttta atggttactt
    15121 tctgctgttt taaaccagta tcatctccgt atttataagg atctctgctt gtatctgtct
    15181 cattaccctg tgcatatgca aaaatagcca tggaaacctg tgcatctccc tcatcatcaa
    15241 agaaagactt ccaacttcca acatatgcag cttcattata aatcaaacca ccagcattct
    15301 tctcatcaat tgtggcttct aacaagttat aaatgctgtc agcctgtgta tatacattgg
    15361 ctgtattcgc ctcatttaca cgttcatatt ctacgttaga aactatcagt tgtttatccg
    15421 gtgcacaact ttctacttcg ttttttaaac ttttaatata actgtttgta ttattatctg
    15481 gataaacatt taccccaata taatcataat ctacagacgc atagcccagt ttctgaacaa
    15541 tatattttac agaagcagca tcaggttgag cagctatgct gacagcattc tttacacctt
    15601 cttttttcag caatgctgaa atatcgccca ttgctttcca gccttcccag ccttctccgt
    15661 cagtaattcc aaggaaattc caattcacct cattaccaat cgttacaata tcaggaagga
    15721 cattcgcctg ctttaacttt gcaattgtct ctcttgtata agtttttgca ctttctactc
    15781 gagttaccga ttgctcttct ttctctgctt tctcccagtc tgccggaaga ttctgtgtac
    15841 ccgcataagt tatttcgtct gaataaagta agacaagatt tgtcttaaga tttgtattag
    15901 atgcttttac agcttttaat gtttttattg cattttccaa agaaagatat gcattttccc
    15961 ctgttggatt tacagcaacc tttaaagata tggtattgat accctgactt tttacatagt
    16021 cgaaaatatt gtctacggac tgactcatat aatttttata tgatttcccc cactccagac
    16081 actgctgata ataagtaaaa tccgctccta aaatagtatt cgctccaatt ccagaaatct
    16141 ttttgtactt cttaaaagca tccttgctta tttctggaat ttcaatctta tctgctgacg
    16201 aacttacttc ttgcgcctta accggatgtg tatccaaact aaatccagtt gttgcaaata
    16261 acatggatgc cattgctatt gctacacatc ttttgatagc cccgctaaat ttttcaagat
    16321 tcttcatttt cattagtaga ttatgattgt ttttcataag tttcccct
//
