LOCUS       c00003_gnlPro..        23228 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NPCBNINB_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-08 00:07:06
            Original ID  :: gnl|Prokka|NPCBNINB_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 157663
            Orig. end    :: 180891
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23228
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[167663:170891]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13228
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23228
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23228
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(521..2254)
                     /locus_tag="ctg3_148"
                     /transl_table=11
                     /translation="MALDGIFLRHIKSEIEKEALGARVSQIYQPNREELVFGLRTFSGN
                     KKLLLSARANSPRVNFCSSTPENPAQPPMFCMLLRKRIGGGKLVGLRQNGCDRVLMLDF
                     ECVNELGDTVMITVVCEIMGMYSNIIIVDSNGVIIDSLKRVDLTMSSKRLVLPNIKYEL
                     PESQNKLNLLKCSVLDVCTAVKNLDTEMPLNKALLRTIEGVSPIVCREIEYKVMEGATN
                     RIEGVLFDRLAVEIEKLKSVCSDCSGKPVVVYREDGKPMDFCFMNVEQYGDFAKVESKE
                     SFSDLLDGFYEARDSRDRMRVKSQSLTKLLNNTLERLARKIAKQKSELERCADREHLRI
                     CGDLLQANIYRIERGAEYVDVENFYDENNAILRIKLNPAISPSANAQKYYKDYRKAKNA
                     EIMLKEQLEKGREELDYINSVLDTVDRAENEKDLAQIREELTEQGYLKVQKGKKPRQTT
                     LPPLEFESSDGFKILVGRNNRQNDKLTLKTASKNDMWLHTKDIHGSHVIVVSDGKEISD
                     TAIYEAARLAAYHSKARNSSQVPVDCTLVRYVSKPNGSKPGMVIYVNNKTLYVKPSQTV
                     E"
     CDS             complement(2269..2754)
                     /locus_tag="ctg3_149"
                     /transl_table=11
                     /translation="MIKINIICIGKIKEKYFTDAIAEYAKRLTAFCKFNIIELSEERIK
                     SNIPNRSQIDEVIFSEGKRIMQKISPSDYVVAMCIEGKSMSSEELSKLIDNASVSGKST
                     VDFIIGGSYGLDESVKKRADVRLSMSRMTFPHQMARMILSEQIYRAFEISSNGKYHK"
     CDS             complement(2776..3564)
                     /locus_tag="ctg3_150"
                     /transl_table=11
                     /translation="LARAVPLFSGSKGNSYYIGSASEGVLIDAGRSCKQIENAMLANGL
                     DMGSIGAVFITHEHTDHCSALRVLAKRYGFKVYSSLGTLNALRAGNKLDPNTDADVITD
                     EVVIGNMRVQRIDTPHDAAESCCYRVTAPDGKSALIATDMGVMLPDVRTAAEQSDFVVL
                     ESNHDINMLKNGFYPYPLKQRILSNRGHLSNEACAKELVNLVEKGTLRLMLGHLSEENN
                     TVPLAMSTSVDLLTSNGMKYKSDYSLDVAPSVSTTKAIIF"
     CDS             complement(3687..4979)
                     /locus_tag="ctg3_151"
                     /transl_table=11
                     /translation="LEKFVVTGGKPLSGEVTISGAKNAAVAIIPAVILCDEPCQIENIP
                     NISDVSLISRILQQMGANVRRINRSSLYIDPTKIRTCNAVTDLVRGMRASYYLLGALLG
                     KYGKAKVALPGGCNFGVRPIDQHLKGFEALGATTQLVDGAIIEAECDSLVGTHVYLDVV
                     SVGATMNIMLAASKAKGQTIIENAAREPHIVDLANFLNSMGADVRGAGTDVIKIRGVEY
                     LHGITYSIIPDQIEAGTYMCAAAATRGCITVKNITPKHLESISAKLREMGVKITEYDEA
                     LKVDASSAPLKRCNIKTMPHPGFPTDCQPQFAALLMSVPGTSIINENVWDNRYQYVSEL
                     IRMGAQISVEGRLAIIEGGVPLTAAPVKATDLRAGAAMIIAALEINGTTEISNIQFIER
                     GYEDVVEKFRGLGADIKKVYFTGDNEQELGA"
     CDS             5710..6027
                     /locus_tag="ctg3_152"
                     /transl_table=11
                     /translation="MENKEKTTTPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENEM
                     SVLNIAEALSMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHVL
                     E"
     CDS             6040..8364
                     /locus_tag="ctg3_153"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCAHCAGKIEAKIAETNGFEDVSFNFATKLLNFKS
                     EKQNPVSEIQAICDSIEDGVTVVDKTPKTNLKKYTYILDNLNCAHCAGKIEAKIAETDG
                     FEDVSFNFATKLLNFKSEKQNPVSEIQAICDSIEDGVTVVDKTPKNDITTKAEPEITKK
                     KINRDTIFLAISIVLAVVSEILHLTLDGVTAVHYVVLAACFVATLLSGYKVFIKGAKNI
                     LKLKIDETTLMAVAVIAAFCLGDFVEAAMVTILFSIGEIFEDRAVDASRRDIEKLANIR
                     PDTATIIVDGAEQVVPAESVEIGSIIEVKPYERVPLDGIIIKGKTTLDTSALTGESLPV
                     DAGEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDAAAQKGNSEKLISRFASV
                     YTPVVVLIAVAIAVIPPLCGLGAFSEWLYRALVCLVASCPCAIVISVPLSYYSGIGAAS
                     EVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLSVNKVNTVGSYSADEVLALAAASEK
                     YSAHPIASAIREKANGLELPELSDYSESAGHGTSAVYNGKTIQCGGSKILSDEQKKIAN
                     KDDSVFVIYDGQLIGSLNVSDTVRPEAKEVISQLKGLGVKNTVMLTGDRQQPAENVKNE
                     LGLSECHAELLPAQKLELFKGLKSKFKGACFVGDGINDAPVLSASDCGIAMGFGSEAAI
                     EASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKALVIILAAFGLAQIWMSVI
                     ADTGVSVVCVIIAARLLKKKY"
     CDS             8563..9804
                     /locus_tag="ctg3_154"
                     /transl_table=11
                     /translation="LKKIFLLLVTALFLLSLYGCNTSSSSNNPTEQTTVTNTDDLSLDS
                     DIETTELNHDYEIYNNGKKVDTLNLYGLFKQIDNGFIYSKINKDSPNEMEYYRYYLDKK
                     NSVKLGSIKNWSMQIHDKAYVNNHLCFTSSTGDITDEENRTLEFIDIDLNKNKMTTVFS
                     DKGGFPYDTVTGADNLVIITKVLDNGTSLELYDTETQKFKQLKYLEFDDKNSIGETIRK
                     VSIDKSTKTISLLVLDCISQNEAFLKIETYDYDMNFQKSYDISNISDDSNELIQGVQVF
                     DFKNNYLFYQNFSITRCIGYIDSDKLKKSDISEDVDDTFSIVSASEDDSDTNLLYKRAE
                     SSSENNYIYLFDTTNKTMKETKFNIEEKGYTIGGISRIGKDNLMILMSPDNADKKSDLN
                     SRIYFTKLSDLNFQ"
     CDS             10001..11623
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_155"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.8e-42, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             11636..12127
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_156"
                     /sec_met_domain="ALS_ss_C (E-value: 1.5e-29, bitscore:
                     95.5, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQEPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIIKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             12188..13228
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_157"
                     /sec_met_domain="IlvN (E-value: 1.1e-82, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 8.4e-60, bitscore: 194.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKLAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(13519..15357)
                     /locus_tag="ctg3_158"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAAEPLNTPVQYVQVARASL
                     ATPKISKAESVYGGVKLTWNKVNGAAKYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRN
                     YTYTVRCISADGKSFTSGYDSKGTTVKYIAAPEISKLENVNGGVKISWGKVSGATKYRV
                     YYKGSKGWTKMVDTTSTSYIDKDVSSGRNYTYTVRCITSDAKKFTSGYNPTGKSVKYVA
                     TPKISKLEVTYDGVKLTWNKVAGAEKYRVYYKDRNGWTKLADTTGTTMLDMNVVSKEFD
                     LSVDDIYYTVRCISKDAKSFTSGYDSKGTPIGDHQDCPEIYSIGAVNNGVEMHWTGDAP
                     KFRVYIKENGSWKKIAETYDNYYVHKGAKSGSNTYTVRGVSKDGKKFTTMFNPTGVTYR
                     YKTSDKTRDAYINYMMNHQSEWMPSLGSDHNLSGVMFLDFDFDGVPELVAQKADSNEYS
                     FHSVVYKFEDGKLKRVGNVNDGFSIYYNKTAKKYEVHDLDIYLNVDEGYYWSGNSIITY
                     DGENLFANMYSARGVGEESNDNIYYRYFDGNDKNISRAKYNEINLKQFNNCVNAHMFTE
                     FIATGYGDASVWGEKTTAENKQSLLDAYNSFSYEKY"
     CDS             complement(15805..17946)
                     /locus_tag="ctg3_159"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAAEPLNTPVQYVQVARASL
                     ATPKISKAESVYGGVKLTWNKVNGAAKYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRN
                     YTYTVRCISADGKSFTSGYDSKGTTVKYIAAPEISKLENVNGGVKITWNKVNGASKYRI
                     YHKNSSDWFRVSDTTSNSIVDKSVGMGTYTYTVRCISDDGKSFESGFNPKGLSIRYNQA
                     PKILETNVVNGGIKVIWNSEENTNYRLYCKTEGKGWTKVCDSKTGVVTHKNLQPNKTYT
                     YTVRAISADAKKYLSGYDPVGMSAKYVATPKISKTEVTYDGVKLAWNKVAGAEKYRVYY
                     KDGEGWNKLADTTGNSYLDMGLVSRELSIKDNSVNGQYIYTVRCISSNGKAFQSGYDTK
                     GSKANLGNECPEIVRVDSMHGGITVSWTDVCEDNSKYRIYVKEKGSWKRLADTTNNYYT
                     HKNVKAGQTYTYTVRCVSKDGKKFTSIYNPSGVTFKYKTTDKTRDAYIDYLLKHESEWL
                     PELKVGNVALAGVQFADLDFDGVPELIVQEAGDKEYYLNAKVYTFKDGKFSLVGFDDYR
                     TYIPNQLTYFYDKSAKKYIINAVELSTSNVDRYLERENYTLNYDGTVLVVRGYSSAHLA
                     LESRGLEYHYYNNTGRTTKQAYNATNVSVLGNCVNAHMYSQFVCCSVDGYPKLWNNYSE
                     TQKKQHLLDSYNAFSYDKY"
     CDS             complement(18143..19165)
                     /locus_tag="ctg3_160"
                     /transl_table=11
                     /translation="MKKLLTALIAFVMCFSVVTTAFAATPDETSDPDLISDIKQAMLDT
                     YYGDEKPDFIEVRIYGTASDGGVYFDFMDSFTHWTDEVEFDIGDYTVSYPRDCPVLLYK
                     NNKVYTLSDAYETGVIDDDMLYELYVWGNLWGKIDVTPKGEDRALLSEIKRVIINKYYN
                     GKAPEYLNVEIVGSTSDETVCFRNIPFMSLGVMIEQTIGDYTYYYNHGDDVMLYKNGNV
                     YSIKEAYESGVIDDSILEELSKMNFGLESNKPNTTVPTEPTTSVATIDEPVTVPDTTSA
                     TSATKPVSTSDTATNDTPSNSQNNSGAVQTGQNSVAVILLVAMLAGCAVIFAKRRNYFK
                     "
     CDS             complement(19359..20036)
                     /locus_tag="ctg3_161"
                     /transl_table=11
                     /translation="MKKFLTALIAFVMCFSVVTTAFAATPDEISESDVASEIRQVMIDT
                     YYGGKEPEYLNIEIVGSTSDGGVYFMHNEGFSLDYSIEETIGDYTYHYNHNDDVMLYKN
                     GNVYSIKEAYESGVIDDSILEELSKMNFGLESNKPNTTVPTEPTTTVATVDEPVTVPDT
                     TSATSATKPVSTSDTATKDTPNNSQNNSGAVQTGQNSVAVILLVAMLAGCGVIFAKRRN
                     HFE"
     CDS             complement(20231..21634)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PYC_OADA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_162"
                     /sec_met_domain="HMGL-like (E-value: 1.4e-48, bitscore:
                     159.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 2.9e-54, bitscore:
                     177.3, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKIRVTETALRDAHQSLIATRMTTEEMLPVLDKLDKIGYYSLE
                     CWGGATYDSCLRFLNEDPWDRLRTIREHCPNTKLQMLFRGQNMLGYRHYADDCVEYLVQ
                     RSIANGIDIIRIFDALNDIKNLKTAIKAANKEGGHAQVAISYTTGPVFTDEYYVEYAKR
                     IADAGADSICIKDMAALLTPTRTESLVKAIKAAVPELPLQLHTHYTSGLASMCLLKGVE
                     AGADGIDTAISPLALGTSHAPTESMVAALSGTEFDTGLDLKQFSDIRAYFMTLREKYIK
                     SGLLDPKMLATDANALIYQVPGGMLSNLLSQLKQAGKEDKLDEVLAEVPRVRKDSGYPP
                     LVTPTSQIVGTQAVFNVITGKRYSMCTNEFKGLVAGEYGTTPMPIDPQFQKKIIGDKKI
                     IKGRPADQLKPELDKLRGEIEQWIEQPEDVLSYAQFPKVALDFFEKRRNAKVGINGDKL
                     DKKNMVHPV"
     CDS             complement(21665..22030)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.7; E-value:
                     8.2e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_163"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.3e-20, bitscore:
                     65.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLRITVNGTAYDVQVEELGGSSAPAAAAPAPAAAPAPAAKPAA
                     PAGAQGSVVVKAPMPGTVVNVVVSAGQAVKAGDDLVFIEAMKMETPVKAPQDGTVATVD
                     VAKGESVDSGKVLVTLN"
ORIGIN
        1 ttaagtctta tgtgtcagta cattcctatg ggcaaggtca gcgacaggga gttttcacga
       61 attaaccgta aaatcacacg cagagaatat gacaaggtaa agctagaaat gatgcgactg
      121 ggaattgacg gctttacaca ggagctttct tccgcagatg aaagctatgt ccccgaatgg
      181 gattttgaag gatgattttt tgattaatgg aactcttgta gcggcgaacc gtgttcgcca
      241 atcatttcgt atgtaaatac gaaatgagca aaaaacaagc tttccataat aatccaatta
      301 attttattgg aacatatgta tcctgtcgaa acgattttac aatcgttccg attggcgaac
      361 gaggttcgcc gctacgaatg aatacacaat tttcttctta ttaaaatcta tgtgtttgaa
      421 catataatat catcagggtg ggcgtccaat gaacgcccct accgattaat tttcaaaaac
      481 aaaacggtca agaaacattt tttagtttct tgaccgtttt ttattcaacc gtttgtgacg
      541 gttttacata cagggttttg ttgttgacat aaatcaccat accaggtttt gagccgtttg
      601 gctttgacac atagcgaaca agtgtgcagt caacgggaac ctgactgctg tttctcgcct
      661 tactgtgata tgccgcaagc cgtgccgcct cgtagattgc cgtgtcggaa atctctttgc
      721 cgtccgaaac aacaattaca tgagaaccgt gaatgtcctt tgtgtgcagc cacatatcgt
      781 tctttgacgc tgttttcaaa gtcagcttat cattctggcg gttgtttctt ccgacaagga
      841 ttttaaaacc gtcgcttgat tcaaattcga gtggcggcaa agttgtctga cggggctttt
      901 tgcccttttg aaccttgaga tagccctgct cggtaagttc ctcacgaatt tgtgcaaggt
      961 ctttttcatt ttccgcacgg tcaaccgtat cgagaaccga gttaatataa tcaagctctt
     1021 ccctgccctt ttcaagctgt tctttgagca taatttcggc atttttagcc ttgcggtaat
     1081 ccttgtaata cttctgagca tttgccgaag gtgagattgc cggattaagc tttatgcgta
     1141 aaattgcgtt gttctcatcg taaaagtttt caacatcaac atactccgca ccacgctcaa
     1201 tgcgatagat atttgcctgt aaaaggtcac cgcatatgcg aagatgctca cggtctgcac
     1261 agcgttcaag ctcactcttc tgctttgcaa tttttcgggc aagcctttca agtgtgttgt
     1321 tcaaaagctt tgtaaggctt tgtgatttca ccctcattct gtcacgactg tcacgagcct
     1381 catagaatcc gtcaagcaaa tcggagaagc tttccttact ctcaaccttt gcgaaatcgc
     1441 cgtactgctc aacattcata aagcagaagt ccataggctt gccgtcctca cgataaacca
     1501 caacaggctt gcccgaacaa tcgctgcaaa cgcttttcag cttttcaatt tcaactgcga
     1561 gtcggtcaaa aagcacaccc tcaattctgt ttgttgcgcc ctccataacc ttgtattcaa
     1621 tctcacggca tacaatcgga gaaacaccct caattgtcct taacagcgcc ttgttaagtg
     1681 gcatttccgt gtcaagattt tttacggctg tacacacatc aagcaccgaa catttaagga
     1741 gattcagctt gttctgcgat tcgggaagtt cgtattttat attcggcagt acaagtcttt
     1801 tactgctcat tgtaagatct acacgcttga gtgaatcgat gatgacgccg tttgaatcga
     1861 caataattat gttgctgtac atacccataa tttcgcatac aacagttatc atcacagtat
     1921 cgccgagttc gttcacgcac tcgaaatcga gcataagaac acggtcgcaa ccgttctggc
     1981 gaagtcccac aagctttccg ccgccgattc tttttcgcaa aagcatacag aacatcggag
     2041 gttgtgcagg attttcgggt gttgacgaac aaaagttcac tctcggtgaa tttgctcgtg
     2101 cagaaagcaa cagctttttg ttgccggaaa aggttctcag cccgaacaca agctcctctc
     2161 tgttcggctg ataaatctgc gacacccttg caccgagagc ctctttttct atttcacttt
     2221 taatatgtct taaaaaaatt ccgtcaagcg ccatagtaac tccgtaaatt atttgtgata
     2281 tttaccgttt gatgaaatct caaacgcacg gtaaatctgt tcgcttaaaa tcattcttgc
     2341 catttggtga ggaaaggtca ttctgctcat tgaaagacgg acatccgccc gttttttaac
     2401 cgattcgtca agtccgtagc tgccgccgat aataaaatca acggtgcttt ttccgcttac
     2461 ggacgcattg tcaatcagct ttgaaagctc ctcactcgac atagactttc cctcaataca
     2521 cattgcaaca acataatccg aaggcgaaat tttctgcatg attcgttttc cctcagagaa
     2581 aataacctca tcaatctgcg acctattcgg tatgttgctc ttaatgcgtt cttccgaaag
     2641 ctcaataata ttgaatttac aaaatgcggt caagcgtttt gcatactctg caattgcatc
     2701 ggtaaaatat ttttccttga ttttgccgat acaaattatg ttaatcttaa tcatatttct
     2761 cttgtttgtt taaggttaaa agatgatggc ttttgttgtg cttacactcg gagcaacatc
     2821 aagcgaataa tcgcttttgt acttcattcc gtttgatgtg agcaggtcta cggatgttga
     2881 cattgcaagc ggaacggtat tattttcttc gctgagatgg ccgagcataa gtcttaaagt
     2941 tcccttttca acaaggttaa caagttcttt tgcacaagcc tcatttgaaa gatgtcctct
     3001 gtttgaaagg attctctgct ttagcggata aggataaaat ccgtttttga gcatattaat
     3061 atcgtgattt gactcaagca caacaaagtc gctctgctct gcggcagttc tgacatcggg
     3121 caacataacg cccatatcgg ttgctataag tgcggatttt ccgtcgggag cagtaacacg
     3181 gtaacaacag ctttccgccg catcgtgggg ggtgtcaatt cgctgaacac gcatattgcc
     3241 gattacgacc tcgtcagtta taacatctgc atctgtgttt ggatcaagct tattacctgc
     3301 cctcaaagca ttgagcgtac caaggcttga atacacctta aagccgtaac gctttgcaag
     3361 cacacgcaac gcactgcaat ggtctgtgtg ttcgtgagtt ataaaaaccg ccccgatact
     3421 gcccatatca agtccgtttg caagcatggc attttcaatc tgcttgcatg aacgacctgc
     3481 gtcaatcagt acgccttcgc ttgccgaacc tatgtagtag ctgttaccct tacttccgct
     3541 gaacagcggt actgctcttg ccaaaacaat caatccttat ctttagtata acgaatatga
     3601 taacacaaat tttaaaattt gtaaattatc tcacaaaaaa gccgttctca caaagaaaac
     3661 ggctttgatt tctaattaaa ttttagtcag gcaccgagct cctgctcgtt gtctcctgta
     3721 aaatacacct ttttgatatc tgcaccaagt cctctgaact tttcaacaac atcttcatat
     3781 ccacgctcaa tgaactgaat atttgaaatc tctgttgtac cgttaatttc aagagcggca
     3841 ataatcatag ccgcacctgc acgaaggtcg gttgccttaa cgggagccgc tgtgagcgga
     3901 acaccgccct caatgattgc aagtctgccc tcaacagaaa tctgcgcacc cattctgata
     3961 agctcgctga catactgata gcgattatcc caaacatttt cgttgatgat gcttgttccg
     4021 ggaacgctca taagcaatgc ggcaaactgc ggctgacagt ctgtcggaaa gccgggatgc
     4081 ggcattgtct tgatattaca gcgctttagc ggagcagatg acgcatcaac cttgagagcc
     4141 tcatcatatt ccgtaatctt aacgcccatc tcacgcagct ttgcgctgat tgattcaaga
     4201 tgcttcggtg taatattctt taccgtaata caacctcttg ttgcggcggc ggcacacata
     4261 tatgttcctg cctcaatctg gtcgggaata atcgaataag taatgccgtg aagatactca
     4321 acgccacgga ttttgataac atccgtacct gcacctctga catcagcacc cattgaatta
     4381 aggaagttcg caaggtcaac aatatgcggt tctcttgcgg cattttcaat aatggtctgt
     4441 ccctttgcct ttgatgcggc aagcataatg ttcattgttg caccaacgga cacaacatca
     4501 aggtacacat gtgtaccgac aaggctgtcg cattctgcct ctataatcgc accgtcaaca
     4561 agctgagttg tcgcaccgag agcctcaaag cctttaagat gctggtcaat cggacgcacg
     4621 ccaaagttac agccgcccgg aagagccacc ttagccttgc cgtacttgcc caaaagtgcg
     4681 ccgagaagat aatatgacgc tctcatacct cttacaaggt cggtcacagc attgcatgtg
     4741 cggatttttg taggatcaat atataaggac gaacggttga ttcgtcttac attagcaccc
     4801 atctgctgaa gaattctgct gataagtgat acatcgctga tgttaggaat attttcaatc
     4861 tggcacggtt catcacaaag aataactgcc ggaataattg caacggctgc atttttcgca
     4921 ccgctgattg tcacttcacc cgataatggc tttccgccgg taactacgaa cttctccaat
     4981 tgttacaccc caattaatgt gtagaagata cttttaacta aataagctaa atatctgaaa
     5041 atgtatatct atatagtgta taagtaaaaa tcaaaaatta tacgaatcta aaattcataa
     5101 tgagaactaa tttgttacat tttattaaaa acgaacccac tcggttacgc agatgtaatt
     5161 taacaattct cttacagaaa atgatactac aaaattgtag taaagtcaac ggaataataa
     5221 aactgtaatc tatttttggg caagttgtac tcaaattatt aatttgttgc tttttttgtt
     5281 tttaatataa ccaaccatgc tttttaaaac cgttttttcc taaaaagaag taattaatta
     5341 aagcaatttt ttgtaaaatt attacaaatt gaaacaagtg ttattttcgt gttatcatca
     5401 ggcatctgag cattttacaa ttcaaattga acacagaaaa atatcgttcc gttattccta
     5461 tgataatttt acaccttcaa tcttcttttt tcaaatttaa aattaacttt ctatactata
     5521 tatactttcc aaacggacac aataaacaag tgaaactttg gggcaaaaaa acttgaaaaa
     5581 cattacattt tttcgtgtgt gtctattgac tttttaaaaa gggaatgcta tattataatt
     5641 aacatatgag catatcttca tatgttcaag tataactatt aacctgagag aaaattaaag
     5701 gggacgccta tggaaaacaa agaaaaaaca accactcccg aaatgcccga cattgatgtg
     5761 ctgtttgagc ttgcagacct ttttaaggtt ttcggtgatt caacccgact tcgcattatg
     5821 tacaccattt cggaaaatga aatgtcggtg ctcaacattg ctgaagctct cagcatggag
     5881 caaagcacaa tttcccacca actgcgtgtg ttaaggcaga acaagctggt gcgtgttcgc
     5941 cgtgaaggaa agcagattta ttacagcctt gacgatgacc atgtgaaacg aatcatagaa
     6001 atgggacttg accatgttct tgaataagga gggagacata tgaggtacaa atatcagctt
     6061 gacaatctca actgtgctca ttgtgcaggc aagattgagg ctaaaattgc agaaacaaac
     6121 ggctttgagg atgtgagctt caattttgcg acaaaacttc tcaatttcaa aagcgaaaag
     6181 cagaatcctg tttccgaaat tcaggcaatt tgcgacagca ttgaggacgg tgtaaccgtt
     6241 gttgacaaaa ctccgaaaac caatctcaaa aaatacacct acattttaga caatctcaac
     6301 tgcgctcatt gtgcgggcaa aattgaggct aaaattgcag aaacagacgg ctttgaggat
     6361 gtaagcttca attttgcgac aaaacttctc aacttcaaaa gcgaaaagca gaatcctgtt
     6421 tccgaaattc aggcgatctg cgacagcatt gaggacggtg taactgttgt tgacaaaact
     6481 ccgaaaaatg atatcacaac aaaggcagaa cccgaaatca cgaaaaagaa aatcaaccgt
     6541 gacacaatct tccttgcaat ttcaattgta cttgctgtag tgtccgaaat tctccacctt
     6601 acacttgacg gtgttacggc tgttcattat gttgtactcg cagcgtgttt tgttgcaaca
     6661 cttctttcgg gttacaaggt atttatcaag ggtgcaaaaa acattctaaa gctgaaaatt
     6721 gacgaaacaa cgcttatggc tgttgcggta attgcggcat tctgtcttgg agattttgtt
     6781 gaggcggcaa tggtaacaat cctcttttct atcggtgaaa tttttgagga tcgagcagtt
     6841 gacgcatccc gccgtgacat tgaaaagctt gcaaacattc gtcccgatac agcaacaatt
     6901 attgttgacg gtgcggaaca ggttgttcct gccgaaagcg ttgaaatcgg aagtatcatt
     6961 gaagtcaagc catacgaaag agttccgctt gacggcatta ttattaaagg taaaacgact
     7021 ctcgacacat cggctctcac aggcgaaagc cttcctgttg atgcaggcga gggcagtgag
     7081 gtactcagcg gtgcaatcaa cggcagtaac cttattaccg tcaaaaccac aaaacatttc
     7141 ggcgacagta ccgcaacaag aattcttcag cttgttgaag atgccgccgc tcaaaaaggc
     7201 aacagcgaaa agcttatttc aagatttgcc tctgtttaca cacctgttgt tgtactcatc
     7261 gcagttgcaa tcgcagtaat tcctccgctt tgcggactcg gagcattcag cgaatggcta
     7321 taccgtgcgc ttgtttgtct tgtagcgtca tgtccgtgtg ctattgttat ttccgtacct
     7381 ctctcctact attcgggtat cggtgcggca tccgaagtcg gtgtactcat caagggcgga
     7441 aaatatattg aggctcttgc aaaagcagat acattcgtat tcgataaaac aggcacactc
     7501 acaagcggca agctcagcgt aaacaaggtt aatactgtcg gttcatacag tgctgacgaa
     7561 gttcttgctc ttgccgctgc aagcgaaaaa tattccgctc atccgattgc ctccgcaatc
     7621 agagaaaagg caaacggtct tgaacttccc gagctttccg actacagcga aagtgccggt
     7681 cacggaacaa gcgcagttta taacggcaaa actattcagt gcggcggttc aaagattctt
     7741 tcggacgaac agaagaaaat tgcaaacaaa gacgattctg ttttcgtaat ttatgacggt
     7801 cagcttatcg gttcgctcaa tgtcagcgac acagtaagac ctgaggcaaa agaggttatc
     7861 tcacagctta aagggctcgg tgtcaagaac acggtaatgc tcacaggcga cagacaacag
     7921 cctgccgaaa atgttaaaaa cgaactcgga ctttccgaat gtcacgcaga gcttctccct
     7981 gctcaaaagc ttgagctttt caagggcttg aaatcaaaat tcaagggtgc ttgctttgtg
     8041 ggtgacggca tcaatgatgc ccctgttctt tcggcaagcg actgcggtat cgcaatggga
     8101 ttcggcagtg aagccgctat tgaagcgtca gacgcagttc tcgcatcagg cacactcaaa
     8161 cagcttccaa aggcaattaa aattgcaaga agtgttatca acaccgtcaa gggcaacatc
     8221 atctttgccc tctcaatcaa ggctcttgta atcatccttg ccgcattcgg tcttgcacaa
     8281 atctggatgt ctgttatcgc cgacacaggc gtcagcgtag tctgcgtcat catagccgca
     8341 agactcctca aaaagaaata ttgatttttt tgcaaatcat atcatttatt atgataaagc
     8401 accgtgagct ttcacaagtt tcacggtgct ttcatttgcc aaaatttttc taaatataat
     8461 cttatattat agtattttaa aatcattgac ttttataatt atgtaaatta taatattttt
     8521 gtcagtgctt gcaactgata aataaacttt ggagagatta atttgaaaaa gatattttta
     8581 ttattagtaa ccgctttatt tttactttca ttatatggat gtaacacttc ttcatcaagc
     8641 aataacccca ctgaacaaac aaccgtaacg aatacagatg atttatctct tgattcagat
     8701 attgaaacaa cagaattaaa tcatgattat gaaatttaca ataacggcaa aaaggtggat
     8761 actttaaatc tttacggctt atttaaacaa attgataacg gcttcatata ttcaaaaatc
     8821 aataaagact ctccaaatga aatggaatac tacagatatt atttagataa aaaaaacagt
     8881 gtaaaacttg gttcaataaa aaactggtct atgcaaattc acgataaagc ttatgtaaat
     8941 aatcaccttt gctttacgtc aagcacgggc gacattacag acgaagaaaa cagaactctt
     9001 gaatttattg atatcgacct taataaaaac aaaatgacga ctgtattttc tgacaaaggc
     9061 ggatttccat atgacactgt tacaggagca gacaatcttg tcataatcac aaaagtgcta
     9121 gacaacggta cttctttgga actgtatgat accgaaactc aaaaattcaa gcaattaaaa
     9181 tatttagagt ttgatgataa aaacagtatc ggggaaacta taagaaaagt ttcaattgac
     9241 aaaagtacaa aaacaatctc tcttttggtt ttggattgca tttcacagaa cgaagctttt
     9301 ttaaaaatag aaacttatga ctatgatatg aattttcaaa aaagctatga tatatccaac
     9361 atttcagatg attcaaacga attaattcag ggtgtacagg tttttgattt taaaaacaat
     9421 tatctattct atcaaaattt cagcataaca agatgtatag gatatataga cagcgataag
     9481 ctgaaaaaat ccgacatatc agaagatgta gatgatactt tttcaatagt atccgcatct
     9541 gaagatgaca gtgatacaaa tttattgtat aagagggcgg aatcaagttc agaaaataac
     9601 tacatatatc tttttgatac aaccaacaaa acaatgaaag aaacaaaatt taatattgaa
     9661 gaaaaagggt acactatagg cggtatatca cggataggaa aagataattt gatgatattg
     9721 atgtcccctg ataatgcaga caaaaaaagt gaccttaatt caagaatata ctttacaaaa
     9781 ctaagcgact taaattttca gtaaacaggc ggtaaaaatc aattaaaatc cattttgcaa
     9841 attatctgtc aaaatcctgc aaaaaattta atttatgggc aatactgctc tttacttttt
     9901 aaggtattta ttgtataatt agcggtaaag caaaagggta tatttaatgt tacaaaacac
     9961 cttttgctca caataaaaag gataggaggg acaaaacata atgatcagcg gtgctgaaat
    10021 tatggtaaaa tgtttggaag ccgagggcgt tgacatagtc tttggttatc ccggtgcggc
    10081 tatctgccca ttttacgata aagtttacga ttcgagcatt acccacattc ttgttcgtca
    10141 ggaacagaac gctgctcatg cggcaagcgg ctatgcaaga tgcagtaatc gtcccggtgt
    10201 ttgcgtggca acttccggtc ccggtgcaac caacctcatc acaggcattg caaccgccta
    10261 tacggactct attccgattg ttgccattac aggtcaggtt cgttccgacc ttctcggcag
    10321 agatgtcttt caggaagctg acatcacggg agcttgtgaa ccgtttgtaa agcacagtta
    10381 tctcgtcagc aaaacagaag accttccgag agttttcaaa gaggctttcc atattgcctc
    10441 aaccggcaga cccggtcctg tacttatcga cattcccgtt gatattcagg aaaatgaaat
    10501 tgaaagtttt gaatatcccg aaagcgtaaa cattatcggt tacaagccga acactaaggg
    10561 acacgcaatt caggttaaaa aggctgttga ggccatcaac gcaagcaagc gtcctgttat
    10621 cgtatcaggc ggcggcgtgc tgagttcggg tatcaaactt aaacttcaaa aatttgcaga
    10681 aactacgggt atccccgtta tttcaactat gatgggcatc ggtgttatgc ccagcgagca
    10741 tgagctttat ctcggaatgc tcggcactca cggcaaggct gttgccaacc gtgctcttca
    10801 cgaagccgac cttgtaatcg tatgcggtgc aagactcggt gacagagctg ttgcggctcc
    10861 cgaccagatg agtgaaaaca caaaggtaat tcacattgac attgaccctg ctgaaatcgg
    10921 taagaatgtt aaaacagaaa ttccgattgt aggcgatatg aaaaatgtca tcaatatgct
    10981 gcttgacagc atcggcgatt acaaggttac aacaatgtgg agcgaaaccg taaagaactg
    11041 gaaaaaagac ctttaccgtg agcctcccgt ttttgacggc tttgttgagc cgagaacact
    11101 tgtcggtcat ctcagtgcaa tgttccgatc aaaggcaatt ctcgttgccg atgtaggaca
    11161 aaatcaaatc tggtgtgcaa acaacttccg tattcgtgag ggcagattcc tcacaacagg
    11221 cggtatgggt acaatgggtt actcaattcc cgccgcaatc ggtgcaaagt ttgcaagacc
    11281 cgaccgtgat gttattgtaa tctgcggtga cggcagtttt cagatggggc ttaatgagct
    11341 tgcgactatt gcaggcaatc agctcggaat taaaatcatc attatgaaaa acgcacgact
    11401 cggaatggtt cgtgaacttc aggacaaaca ctacggcggc agacactctg caacaattct
    11461 caacggtgat cccgacttct tgaagattgc cgatgcttac ggcattgacc atgcagaggc
    11521 tcattcaaac aaggaagccg aaaacatcat caagggtatt gttgattcgg aaaaaccgtt
    11581 cattcttgtt tgcgatgttc accccgacac tccgtcaatt taatgaggtg ataaaatgca
    11641 gtatacatta tcaatacttg ttgaaaatca ggcgggcgtt ctttcaaaaa tttcgggact
    11701 tttctctcgc cgaggtttta acatcgactc acttgcagta ggtgttactc aggaaccgtc
    11761 ggtttcccga atcacaatcg ttgcaaacgg tgacgagtac attgttgaac agcttgaaaa
    11821 acagctcaac aagctcattc ccgttattaa ggtaaaaagg cttaacgagg gcgaatttat
    11881 cagccgtgag cttgttttaa tcaaggttca ctgcgccgcc tcaaaaagag ccgaaattat
    11941 caaaacggtt gaaattatgc aggcgaaaat cgttgatgta tccccttcgt cagttaccgt
    12001 tgagtactgc gaatgtgcaa gccgcatcaa cacgcttgtt gacttactca agccttatgg
    12061 tatccgtgag attgtaagaa caggtactgt tgccattgac agaggcacag cttcggtttc
    12121 cgtttaatct tacagttagc atatatttta atttatatgc cgcgtttgcg gtaaggagga
    12181 ctttaatatg aaagactaca caaaaaacat gacagcacca atctactatc agtcagattg
    12241 taaccttgac cttctcaagg gtaagaaaat tgctattatc ggttacggca gccagggtca
    12301 tgcacacgct ctcaacctca aggattcagg ttgcgatgta atcatcggtc tttacaaagg
    12361 cagcaagagc tgggcaaagg ctgaggcaca gggctttaag gtatatacat cggcagaagc
    12421 tgcaaagcag gctgacatca tcatgattct tatcaacgat gaaaagcagg cagctcttta
    12481 caagaacgac atcgagccaa acctcgaagc aggcaatatg cttatgttcg ctcacggctt
    12541 taacattcac ttcggttgca tcaagcctcc aaaggatgtt gatgttacaa tggtagctcc
    12601 taagggacct ggccacacag ttcgttcaga gtatcaggtt ggtaagggtg taccttgcct
    12661 cgttgcagtt gagcaggatg ctacaggtca ggctaaggat ctcgcacttg catatgcact
    12721 cggtatcggt ggcgcaagag ccggcgttct tgaaacaaca ttcagaacag aaacagaaac
    12781 agacctcttc ggtgaacagg ctgttctttg cggcggtgtt tgcgcactta tgcaggcagg
    12841 ttttgaaaca ctttgcgatg caggttacga cccaagaaac gcttactttg agtgtatcca
    12901 tgagatgaag ctcatcgttg accttatcta ccagtcaggt tttgcaggca tgagatattc
    12961 aatctctaac acagctgagt acggtgacta catcacaggt ccaaagatca tcacagagga
    13021 tactaagaaa gctatgagaa aggttctttc tgacattcag gacggtacat ttgctaagga
    13081 cttcctcctt gacatgagcg atgccggttc acaggttcac ttcaaggcta tgagaaagct
    13141 cgctgccgaa gctcctgccg aagtattcgg taaggaagtt agaaagctct acagctggtc
    13201 tgacgaagat aagctcatca acaactaatg ttttttagtt cgtgaagtta gtttgatata
    13261 ttcaaacttc tgtcacccga gcattacata gtacgaattt agggtagctt gattttcaag
    13321 ctaccctttt tgcgagcacc tcgcccgcag ttcgtgaagt tagtttgata tattcaaatt
    13381 tctgtcaccc gaacattaca tagtacgaat taacggttca gtcaatttgg ctgaaccgtt
    13441 tttttgttgt gcaataaaag ggttcagctt tttacggctg agcccttttg cagttaaaac
    13501 ttattaattt ttaaataatc aatacttctc ataggagaaa gaattatatg cgtcaagcaa
    13561 agactgctta ttctcagcgg tagttttctc accccatacg ctggcatcac cataacctgt
    13621 cgcaataaat tcggtaaaca tatgtgcatt cacgcaatta ttaaactgtt taaggttaat
    13681 ttcgttatat tttgcccgtg aaatattttt gtcattaccg tcaaaatatc tataataaat
    13741 attatcattt gattcttcgc ctacgcctct tgccgaatac atatttgcaa aaagattctc
    13801 tccgtcgtat gtgattattg aattacccga ccaatagtaa ccttcatcta catttaaata
    13861 tatatccagg tcgtgaacct catacttttt ggcagtttta ttatagtata tcgaaaaacc
    13921 gtcgttaaca tttcccactc tttttaactt accgtcttca aatttgtaaa caacggaatg
    13981 gaaactatac tcattggaat cagccttttg tgcaacaagt tccggaactc cgtcaaaatc
    14041 gaaatccaaa aacataacac ctgacaaatt gtgatcactt cccaagcttg gcatccattc
    14101 actctgatga ttcatcatat aattgatata agcgtctctt gttttatcgg atgtcttata
    14161 tctgtatgtt acaccggttg ggttaaacat cgtagtaaac tttttaccgt cttttgaaac
    14221 acctcttacc gtataagtgt tactgccgga ctttgcaccc ttgtgaacat aatagttgtc
    14281 ataagtttct gctatcttct tccaagaacc gttttcttta atataaacac ggaactttgg
    14341 cgcatctccc gtccaatgca tttcaacacc gttgtttact gcaccaatac tgtaaatttc
    14401 gggacaatcc tgatgatcgc caatgggcgt accctttgaa tcgtagccgc ttgtaaaact
    14461 cttagcatct ttgctgatac aacgaaccgt gtaataaata tcatcaacgc ttaaatcaaa
    14521 ttcctttgaa acaacattca tatcaagcat agtcgtgcct gttgtatcgg caagctttgt
    14581 ccaaccgttt ctgtccttgt agtacacacg atacttctct gcacctgcta ccttgttcca
    14641 tgtcagcttt acgccgtcat atgtaacctc aagttttgaa attttcggtg tggcaacata
    14701 ctttaccgac ttgcctgtcg ggttataacc gcttgtgaat ttctttgcgt ctgatgtaat
    14761 acatcttaca gtataagtgt aatttctgcc ggatgaaaca tccttgtcga tatatgaggt
    14821 tgaagttgta tcaaccattt ttgtccagcc tttactgcct ttgtagtaaa ctctgtattt
    14881 agttgcaccg cttactttgc cccaagagat tttcacaccg ccgtttacat tttcaagctt
    14941 tgaaatttcg ggggcggcaa tatattttac agttgtcccc tttgaatcat aaccgcttgt
    15001 aaagctcttt ccgtcagcag aaatacatct tacggtatag gtgtaattcc tgcccgatga
    15061 aacatccttg tcgatatatg atgttgaagt tgtatcgacc attcgtgtcc aacctttacg
    15121 gcctttgtag taaactctgt atttagccgc accattcact ttgttccatg taagctttac
    15181 accgccgtaa acgctttcgg cttttgaaat tttcggagtt gccaagcttg cccttgcaac
    15241 ctgtacatac tgcacgggtg tgttaagtgg ttcagccgca tttgcagaaa ctgccgaaac
    15301 cgcaaccgca gacatcgaca ttaccgccgc catggctata ggtaaaaact ttttcatatc
    15361 tatccctcac tttgtaaata ttctacgcat tattaagaac tttcgctaaa tttttatgca
    15421 agttaattgt aacattaaat tgttaaaaaa acaatacttt tcaatacact ttttcattta
    15481 ttttatattt aataatattt aaaatagcaa aaagccgctc tcaataacga gaacggcttt
    15541 tattatgtca aagcatatga gcatcaacat aaaatttcat caaagcgggc ggataatatc
    15601 cgcctctaca gaattgttca aatggtagct atattacgct cgggcataaa tattttttat
    15661 tcgtcgaact tctgtcacca gagcgttaca tagtacgaat taacggttca gtcaatttgg
    15721 ctaaaccgtt tttgttgcgc aataaaaggg ttcagatttt tacggctgaa cccttttgca
    15781 gttaaaactt atcaattttg acaatcaata tttgtcgtaa gaaaaagcgt tgtatgaatc
    15841 aagaaggtgc tgtttcttct gtgtttcact ataattattc caaagttttg gatagccgtc
    15901 aacagaacag caaacaaact gactgtacat atgtgcattt acacaattac cgagtacact
    15961 cacatttgtg gcattatatg cctgttttgt tgttcttccg gtattattgt aataatggta
    16021 ttccaatccc cgactttcaa gagccaaatg agcagaagag tatccacgaa caaccaaaac
    16081 tgtgccgtca taattcaatg tatagttttc gcgttcaaga taacggtcaa catttgaggt
    16141 tgacaattca acggcattaa ttatatattt cttagcagat ttgtcataga aataagtcag
    16201 ttgattcggg atataagttc tataatcatc aaatccgact aacgagaact ttccgtcctt
    16261 aaaggtatac acctttgcat tcaaatagta ttccttatct cctgcttcct gtactataag
    16321 ctcggggaca ccgtcaaaat cgagatcggc aaactgcaca ccagccaaag caacatttcc
    16381 taccttgagt tcaggtaacc attccgattc atgcttgagc agataatcta tgtatgcatc
    16441 tcttgtttta tctgtagtct tatacttaaa tgtcacacct gacggattat agatacttgt
    16501 aaatttcttg ccgtccttag aaacacatct tacggtataa gtgtaggtct gtcctgcttt
    16561 tacgttttta tgagtgtaat aattatttgt tgtatcagca agccttttcc acgaaccttt
    16621 ttcttttaca taaatacgat actttgaatt atcttcgcaa acatctgtcc atgaaactgt
    16681 aattccgcca tgcattgagt caacacgaac aatctccgga cattcattgc ctaaattcgc
    16741 cttagaacct tttgtatcat aaccgctttg aaaagccttg ccgttacttg aaatgcaacg
    16801 aacagtataa atatactgac cgtttacgga attatctttt atgcttagtt ctcttgatac
    16861 aagtcccata tcaagataac tgttacccgt tgtatcggca agtttgttcc aaccctcacc
    16921 gtctttgtag tacacacgat atttttctgc acctgcaacc ttgttccatg ccagctttac
    16981 gccgtcatat gtgacctcag tttttgaaat tttcggtgtt gcaacatatt ttgcgctcat
    17041 tcccactggg tcataaccgc tcaaatactt tttagcgtcg gcactgattg ctcttacagt
    17101 gtatgtatag gttttattcg gctgtaaatt tttatgtgtc acaacacctg ttttgctatc
    17161 gcatactttt gtccagccct taccttctgt tttgcagtac aatctgtaat ttgtattttc
    17221 ttcagaattc caaatcacct taataccgcc atttacaaca ttggtttcaa gtattttagg
    17281 agcttgatta tatctgatac ttaagccttt tgggttaaat ccactctcaa aactctttcc
    17341 gtcatcactt atacacctca cggtataagt ataggttccc ataccaacag atttatcaac
    17401 tatagaatta gaagtcgtat ctgatactct gaaccaatct gacgaatttt tatgataaat
    17461 tctatacttt gatgcaccgt ttactttgtt ccatgtaatt ttcacaccgc cgtttacatt
    17521 ttcaagcttt gaaatttcgg gggcggcaat atattttaca gttgtcccct ttgaatcata
    17581 accgcttgta aagctctttc cgtcagcaga aatacatctt acggtatagg tgtaattcct
    17641 gcccgatgaa acatccttgt cgatatatga tgttgaagtt gtatcgacca ttcgtgtcca
    17701 acctttacgg cctttgtagt aaactctgta tttagccgca ccattcactt tgttccatgt
    17761 aagctttaca ccgccgtaaa cgctttcggc ttttgaaatt ttcggagttg ccaagcttgc
    17821 ccttgcaacc tgtacatact gcacgggtgt gttaagtggt tcagccgcat ttgcagaaac
    17881 tgccgaaacc gcaaccgcag acatcgacat taccgccgcc atggctatag gtaaaaactt
    17941 tttcatagtt atccctcact ttgtaaatat tctacgcatt attaagaact tttgctaatt
    18001 ttttatgcaa gttaattgta acattaaatg atataaaaag caatacatct tgataaacta
    18061 tcacaaattt ttaagctaaa ataaataaac cgttcacaaa agcgagaacg gtttatttta
    18121 tatattctgt tgatgttttg aattatttaa aataatttct gcgttttgca aaaattactg
    18181 cacaccctgc aagcattgca acaagaagaa ttacagcaac gctgttctgt cctgtttgaa
    18241 ctgcaccact gttattctgt gaattgctcg gtgtgtcatt tgtagctgtg tcgcttgttg
    18301 aaacaggctt tgttgccgaa gttgcagaag ttgtatcggg tactgttaca ggttcgtcaa
    18361 ttgttgcaac cgaagttgta ggctcagtag gaacagttgt attcggttta ttagattcca
    18421 aaccaaaatt catttttgac aattcttcaa gaatactatc gtcaataact ccgctttcat
    18481 aagcctcttt aattgagtaa acattgccat tcttataaag cataacatca tcgccatggt
    18541 tgtaataata agtatagtca ccaattgttt gttcaatcat aacgcctaaa ctcataaagg
    18601 gtatatttct aaaacatact gtttcatcac ttgtagaacc aacaatttcg acattcaaat
    18661 attcaggtgc tttgccattg taatatttat ttataattac acgctttatt tctgaaagga
    18721 gagctctatc ttcacccttt ggggtaacat ctatcttacc ccaaagattt ccccaaacat
    18781 ataattcata gagcatatca tcatcaatta cacctgtttc ataggcatct gacaaggtat
    18841 atactttatt attcttgtat aacaaaacgg gacaatctct cggataagaa acagtataat
    18901 cacctatatc gaattccact tcatctgtcc agtgtgtaaa actatccata aaatcgaaat
    18961 acacgccacc gtcactggct gtaccatata ttcttacttc aataaaatca ggcttttcat
    19021 cgccataata tgtatctaac atagcctgtt taatatctga aatcaagtct ggatcagaag
    19081 tttcatcagg tgtagcagca aaagctgttg ttacaaccga aaagcacatt acaaatgcta
    19141 tcaatgcagt taaaagtttt ttcattttta tttcctcatc ttttatttat tctatctgta
    19201 ataatggtat acgcaacaga tattcaattt acatcattat accgctaaaa tatatgtaat
    19261 gcaatatagt tgctaaaaat tcacataaaa taatcagcaa aataaaaacc gttctcaata
    19321 acgagaacgg tttttatagg gattatttga tttgtaaatt actcaaaatg atttctgcgt
    19381 tttgcaaaaa tcacaccgca acctgcaagc attgcaacaa gaagaattac cgcaacgctg
    19441 ttctgtcctg tctgtacagc accgctgtta ttctgtgaat tgttcggtgt gtcttttgta
    19501 gctgtgtcgc ttgttgaaac aggcttagtt gccgaagttg cagaagttgt atcgggtact
    19561 gttacaggtt cgtcaactgt tgcaaccgta gttgtaggct cagtaggaac agttgtattc
    19621 ggtttattag attccaaacc aaaattcatt tttgacaatt cttcaagaat actatcgtca
    19681 ataactccgc tttcataagc ctctttaatt gagtaaacat tgccattctt ataaagcata
    19741 acatcatcgt tatggttgta atgataagta taatcaccaa ttgtttcttc aattgaataa
    19801 tcaaggctaa agccttcatt gtgcataaaa tatactccgc cgtcacttgt tgaaccaaca
    19861 atttcaatgt tgagatactc aggctcttta ccaccgtaat atgtatctat catcacctgt
    19921 ctgatttctg atgcaacatc cgattctgat atttcatcag gtgtagccgc aaaagctgtt
    19981 gttacaaccg aaaagcacat tacaaatgct atcaatgctg ttaaaaattt tttcattttt
    20041 atttcctcat cttttattta ttctatctgt aataatggta tatgcaacag atattcaatt
    20101 tacttcatta taccgctaaa atatatgtaa tgcaatatag ttgctaaaaa tttagcaaga
    20161 ataattctgc tcaaatgaaa atgccacttt catagcgaaa gtggcataaa tgttaatttt
    20221 agttgtcaaa tcaaactggg tgaaccatat ttttcttgtc aagcttgtcg ccgttgatgc
    20281 caaccttggc atttcttctc ttttcaaaga agtcgagggc aaccttcggg aactgtgcat
    20341 aagaaagaac atcctcaggc tgttcaatcc actgctcaat ctcgccacgg agcttatcaa
    20401 gctcaggctt aagctgatct gcaggacggc ctttgataat cttcttgtca ccgataatct
    20461 tcttctgaaa ctgaggatca atcggcattg gagttgtacc gtactcaccg gcaacaagtc
    20521 ccttgaactc gtttgtgcac attgagtagc gcttgcctgt gattacattg aatacagcct
    20581 gtgtgccgac aatctgtgat gtcggagtaa caagcggagg ataacctgaa tccttacgaa
    20641 cacggggtac ttctgcaaga acttcgtcaa gcttgtcttc tttaccggcc tgcttgagct
    20701 gtgaaagaag gttggaaagc ataccgccgg gaacctgata gataagagcg ttagcgtctg
    20761 ttgcgagcat cttaggatca agaagtcctg acttgatgta cttctcacgg agagtcataa
    20821 agtaagcacg gatgtcagag aactgtttaa ggtcaagacc tgtgtcgaac tctgtgcctg
    20881 aaagagcggc aaccattgac tctgtaggtg cgtgtgatgt accgagagcg agtgggctga
    20941 ttgctgtgtc aatgccgtcg gcacctgcct caacaccctt taaaagacac attgatgcaa
    21001 gacctgatgt gtagtgggtg tggagctgaa gcggaagctc cggaacagcg gctttgatag
    21061 cctttacaag gctttcggtt cttgtcggag taagaagagc agccatatcc ttgatacaga
    21121 ttgaatctgc acctgcgtct gcaattctct tagcatactc aacatagtat tcatctgtga
    21181 atacaggacc tgttgtgtag ctgatagcaa cctgtgcatg accgccttct ttgttagcgg
    21241 ccttgatagc tgttttaaga ttcttgatgt cgttaagagc atcaaaaata cggataatgt
    21301 caataccgtt tgcgattgaa cgctgaacaa ggtactcaac gcagtcatcg gcatagtgac
    21361 gataaccgag catattctgt cctctgaaaa gcatctggag ctttgtgtta gggcaatgct
    21421 ctctgattgt gcggagtctg tcccacggat cttcgtttaa gaatctgagg catgagtcat
    21481 atgttgcacc gccccagcat tcgagtgagt aataaccgat tttatcgagt ttgtcaagaa
    21541 cagggagcat ttcctctgtt gtcattcttg ttgcaatgag tgactgatga gcgtcacgca
    21601 gagcagtttc ggtaactctg attttttttg ccattttaca gcatcccttt ctccgaatta
    21661 ttgattagtt aagtgttacg agaaccttac ctgagtcaac tgactcgccc tttgcaacat
    21721 caactgttgc aactgtgccg tcctgcggag ccttaacggg agtttccatc ttcatagcct
    21781 cgatgaatac gaggtcatct ccggccttaa cagcctgtcc tgccgaaaca acaacattaa
    21841 caactgtacc tggcatagga gcctttacaa caacagaacc ctgagcgcct gcgggagctg
    21901 ccggctttgc tgcaggagcg ggagcggctg caggagcagg agcggctgct gcgggagctg
    21961 aagagccacc gagttcttca acctgaacat catatgctgt gccgttaact gtaattctta
    22021 aattcttcat ttttagtatc cccttttatt ttaacaagta atcatttatc agatagttga
    22081 atgcttcttt gaaagtgttg aaacacgctt gcccgagagc atatcaagag cagaaataag
    22141 agtctgacgg agctgagctt cttcaacaat accgtcaaca tagccgttct gagcggcatt
    22201 gtaagcagaa agattctcgt cagcaaactt ctgagcaacc tcagcctgct tatctgtggc
    22261 aacattcata acttcgggag ccataatgaa tgcggcagcc tcaacattaa caggtgaaat
    22321 aactgcatcg ggaagtgcgt aaacaacatc tgcattagcg cctgtgccag caagagcaac
    22381 atagcctgaa ccgattgcct tgcctgtaac aacagaaatc ttgactgttg ttgcctcagc
    22441 ataagcggct gacgcctttg ttgccgactt gattgactca aagcccgggc agtttacgaa
    22501 tgttacaaca gggagtgaga aagcgtcgca gaaacgaaca aactttgcta ccttgtttgc
    22561 agacttgcaa ccaagctcct tgccctttgt aacaacaata cctacaacct gaccgccgag
    22621 tcttgcaaaa cgaacatttg cttccttacc gtaatcattg aagagcttta caatgctgtt
    22681 gccgtcaaca gttctgctga ctacacaacc gcaaccgtcc tctgccggag cttcttcaaa
    22741 tgactgagga gccattgtga ggttatttga cggaagataa aggataagtt cctttgcagc
    22801 cttgattgcc ttgtctgcat cgtcacaaac gattgaggca ataccgtttt cagcattgta
    22861 agcggcatcg gaatgcttgc ctgttaccga aagtgaaagc tgtgcgtctt tgctcatgat
    22921 aacgatgtct gcgcttgcgg cgttaagagc gtttgttccg aggcaagtgc cgagaacaac
    22981 cgagatctgc ggtacaacac cggaaagtga cgcagccgca ttgagaacat caccgcaacc
    23041 tgcgagaagc tctgtaacct gattaagtct gccgccgacg ctgtcataga aacctacaac
    23101 aggagcgcct gtcttgagtg caagaccata cagcttttta agcttggcag cctgtgcctt
    23161 actcatggca ccgccgcaaa tgtcgctgtt ctgtgcaaac gcataaacag gcataccttc
    23221 tactgttc
//
