LOCUS       c00007_gnlPro..        15852 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NPCBNINB_7.
ACCESSION   c00007_gnlPro..
VERSION     c00007_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-08 00:07:06
            Original ID  :: gnl|Prokka|NPCBNINB_7
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15852
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15852
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2859:5852]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2860..5852
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15852
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15852
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(94..1281)
                     /locus_tag="ctg7_1"
                     /transl_table=11
                     /translation="MKKKIFILLLCVVLIATCILCGLTGIFGNDSQNSPKPQTPDTAVT
                     ENTTFPSKVDSLTLKVGESKLIELSSEKAKSVTKWTSSDSKIVTVDDGGRVDALKEGTA
                     LISAISKDKSKSEFQVTVAKSTTKKQQSYSTCITANLDKLENNERNTAKNLYAIKVNRT
                     ANCVTVYTYDEKGKYTIPVRAMICSTGLDNSTITGDYTIGIKSEWLFLVGDVFGRYISG
                     ISGDYLFHSVPYYTMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWVYDNCPTGTNVSI
                     YDDAENAGPLGKPDTIKITDFTNKWDPTDSNKKCPYAKATPIISGANDYTIKSGGEFYA
                     LAGVTAVDTCGNDITSNIEVFGNVVTTRKGKYKVTYSVTDALKRTSSVTITVTVQ"
     CDS             1446..1982
                     /locus_tag="ctg7_2"
                     /transl_table=11
                     /translation="MVIIMAHPIKHFRTITRHRHKVIANCARAGILRQGLIHDLSKYSP
                     TEFIPGAKYFQGTRSPNEKERELYGYSQAWLHHKGRNRHHYEYWNDYNPKTKQIENVEM
                     PVKYVIEMFCDRVAASKIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRD
                     EGEEKTFAYIRSMKK"
     CDS             2102..2593
                     /locus_tag="ctg7_3"
                     /transl_table=11
                     /translation="MKTDRVITAMIEYFGSDKKRIHHFLKVYSFAKTIGESENLLPDDQ
                     ELLEISAIVHDIGIKVSEEKYNSSAGKYQELEGPHEAEKLLAALGYEKTFIDKVCYLVG
                     HHHTYGNIDTLPYRILVEADFLVNLYEDDSSRSAAEQAYDKIFRTNTGKNLLKIMFLIP
                     "
     CDS             2860..5097
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_4"
                     /sec_met_domain="Gly_radical (E-value: 1.1e-40, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 3.1e-271, bitscore:
                     893.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQRNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDEDGIAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             5097..5852
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.2;
                     E-value: 1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_5"
                     /sec_met_domain="Radical_SAM (E-value: 7.7e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNAVKGFVHSIETFGSVDGPGVRFVIFLSGCAMRCQFCHNPDT
                     WKHDENTVEYTADELLNKALAYRPYWKNKGGITVSGGEPLLQIDFLLDLFKKAKKQGVN
                     TCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDIKHIDNEQHKILTGQPNTNILEMARQ
                     LSDMGKPVWIRHVLVPERNDKDEYLFRLADFIRSLRNVERVEVLPYHTLGVYKWKALGY
                     DYPLEGINPPTKERVKNAEMILNGEKTRD"
     CDS             6370..6588
                     /locus_tag="ctg7_6"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEEVAKEEPQAEVTADELAEEE"
     CDS             7164..8960
                     /locus_tag="ctg7_7"
                     /transl_table=11
                     /translation="MKKIQKKLSVVLAVMMVLCMFTALPFSASAAETSEETSAGNKINV
                     TSNVTDPVSYDYNAQTEQVVVTYLLKADHMIVDTQSSLTYDSKVLKLASTTTTNTKKKV
                     FPVFQSSIVWNTSITNQVYFNCSSLDLFNFKSENVYCTFTFDVVGSGDTTVNLNVDYLT
                     GTEAESYDDFFESEKKDIDYIYDSANKVEGAAFTAKAVLVQGEEPTTVPQPATEPTQPQ
                     SGVSVTGDIALPLADDGNGIYTGSTELEAGSYTFKMSVNGVAFGNGSTFTDKTTNATYS
                     SKWKSSTTLKATGGKYTFKFNTAKNTLTIEYLAPSKASIVGDINLDLQATKDANVYSAS
                     VKLNKGNYEFRVMNQDVRYCCGYTYKDFTVGSQFSSKWSSASTLAASGGTYTFSYDIDT
                     NKLTISYLPSGAEVSVVGNFTLALAKTDKENVYSGTKTLKAGKYQIKMNNYGKLCGTSA
                     VVKDATPGLVFSPKWSKYTTFVATGGTYTFTYNTATNKLVVTADKGDIPVKVTGDINLT
                     LKKSDTNVFTGSVKLKRGDHSFKMNVNGTDFCSGATIRNATTGTVKYNSKFTSATTLVA
                     IGGTYTFTYNTLTNQLSVKYSK"
     CDS             complement(9501..10082)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hexapep"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_8"
                     /sec_met_domain="Hexapep (E-value: 6e-13, bitscore: 40.9,
                     seeds: 216, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLLFALRSIFLLPHFFVFKLCEKHDVLCKDLESWRKLCPKKNNC
                     SYTYLFFYMMCHFKEFRNVFYLRLGNIKYFLKIFCKPLDSLYLTSKNMGPGLFIQHGFS
                     TIVGVETMGSNCWINQQVTVGHTEKGRPKIGNNVKIMTGAKVLGNVTIGDNVIIGAGAI
                     IVKDVPSDCVVVGSRAYIVKRNGKKVREEL"
     CDS             complement(10136..11266)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_9"
                     /sec_met_domain="Fer4_7 (E-value: 4.6e-09, bitscore: 29.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIFPSKSECCGCSACKQICPKGAIAMKPDSEGFLYPQIDVSLCI
                     ECGACQKICAFQNGYEKNHSKTAYAIKHKDFNTRFTSRSGAAFIALSDYILNKKGSVYG
                     AAFQDDFSVSHIRATDRYVRDKFKGSKYVQSDMKDTFKSVKNDLNNDMYVMFSGTACQV
                     AGLKRYLGKCDTSKLYTCDIACHGVPSPIIWKEYLKHCEKKFCGKVTKADFRDKTIGWN
                     THKEAIWIDDNKHILNGYTYLFYEDDIERPSCYNCKYSNIDRPADLTLADFWGIDRVVE
                     NFNDNKGVSLLLVNSEKGSRILNKVIGNIHCVECDLNASIKSNPNLSCPTAKPDSREDF
                     WNFYYKNGFEKTFKKYYNKIIIKKIKRRIMNKDEVL"
     CDS             complement(11269..12354)
                     /locus_tag="ctg7_10"
                     /transl_table=11
                     /translation="MKKIGIITFHRAKNYGAVLQAYALQHTLKQLGSDCEIVDYKCENI
                     DNGYKPFQFSKTDPIKSILKSIVMYRKRAKKIEQFSSFYNNYLKISNKTYSNSDISECK
                     NLYDAFISGSDQVWGPGKEGINPDSIYFLSFADDNQKYSYAASFGVADISDVKAMQLRP
                     LLKNFQSFSVREKSALNIVKKITGKNGVCHIDPTLLLNKDEWQKISVKKIDKPYILVFN
                     VKPVKSLIDFAEKLSKKTGIPVVYITDNPQKKRKNFTYVSAPTVEEFLGYFANADYTVT
                     NSFHGTAFSVIFHKNMFVEYETAKGFNHRAKNLLQTIGINREIKDGEAVTTDIDWNKVD
                     NILQAERKHSLDYLKDIIKGE"
     CDS             complement(12370..13272)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_11"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.9e-31,
                     bitscore: 99.7, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNVEITVFTPSYNRAKTLPRVFECLKKQTYKSFEWIIIDDGSED
                     NTKDVVDGFLKENNFFDIIYVYQKNQGKHIATNNAVKMCRGNFFITLDSDDTCTNDALE
                     TFVNEWNKIPKQEQKKYYGISCRTYDKDGKINGTQMNVPYIDSNDLDLRFKLNITGELW
                     GMIRTDIMREFPFPVVEGYHFYPENVIWHNVGRKYICRYLSTALRYYIQDQENAVTNVN
                     RKKASKEKFVMHLHYINDCWDYRKYNRKRYLEHIVAITRDGLANGYKLSEILTMLKTKP
                     RRLLVLLTSPIGYLLYKHS"
     CDS             complement(13286..14815)
                     /locus_tag="ctg7_12"
                     /transl_table=11
                     /translation="MPKSAGKQMSINIIASIVSFAVTVGINFFLTPYLVKEVGSDAYGF
                     IGLANNFVQYATIVTTALNSISGRFISIAYHKGDVEKSSKIFSSVLVADLFLAAVMLIL
                     SSIFVCFLDTVLKIPSNLVSGVKITFAFAFLTFVVSTVTAIFTTAAFVKNRIDINSIRD
                     IISNLIKVALIVLLFAIFPAQLYFVTLASFGSGIFLLLANITVKKKVLPEVKADIRKFD
                     IKIVKTLLASGIWLSLAQLCQVLLSGLDLLICNLTLGTALMGLLSIAKTVPNSIGNLTV
                     ILGSVFTPHYTILYAKKKIPELIIEAKFSTKIVSFILSTPIAGFIAFGRQFYILWQPTK
                     SPEEITMIQFMSVLTCITFLCSSQTQSLMMINTVCNKLRLPVFVNLTVGIVSVIVAIAA
                     CNLTDYGVYFVAGTSSVLMGLRALIFTPAYSAYILKQKLSIFFPTVIRDCVGFIIILVL
                     FSIISNLITVTGWSSFIFICAICGILAYALSLPLLFNKAELCKLKNKLTKK"
ORIGIN
        1 attttcaatt ttccattttc aatttaaaat ctccgttcgg gcatctttat ttttgttttt
       61 gcggaactat cttcttaaat tgactgcggc ggtttattgc accgttaccg taatcgttac
      121 gcttgatgtt cttttaagcg catcggtgac tgaatatgtt accttgtact tgccttttcg
      181 ggtggttact acattgccga aaacttcgat attcgaagtt atgtcgttgc cgcaggtgtc
      241 aacggctgtt actcctgcaa gggcgtaaaa ttcgccgccg cttttgattg tgtaatcgtt
      301 tgcaccgctg attattggtg ttgctttggc atacgggcat tttttattgc tgtctgtcgg
      361 atcccatttg ttggtgaaat cggtaatttt gattgtatcc ggttttccga gagggcctgc
      421 attttctgcg tcgtcatata tgcttacatt cgtgcctgtg gggcagttgt cataaaccca
      481 ctttgcatcc gaaaccgcaa gtcttacgca tccttgtgat gcctgttcgc caagcttgtt
      541 gaattcctca agctccaaat cttcttcgct cattgtgtag tagggaacgg agtggaaaag
      601 ataatcgccc gaaattccgc tgatgtatct tccgaaaaca tcgcccacaa ggaaaagcca
      661 ttcggacttg attccgattg tgtagtcacc cgtgattgtc gaattgtcaa gacctgtgga
      721 gcaaatcatc gcccttacgg ggattgtgta cttgcccttt tcgtcatatg tgtaaaccgt
      781 cacgcagttt gccgtgcggt tgaccttgat tgcgtacagg ttttttgccg tgttacgctc
      841 attgttttca agcttgtcaa gatttgccgt tatacaggtt gagtagcttt gctgtttttt
      901 cgtggttgat tttgccaccg taacctgaaa ttccgacttt gatttgtctt ttgaaattgc
      961 agaaatcaga gccgtaccct ctttgagagc gtcaaccctt ccaccgtcat caacggtaac
     1021 aattttactg tccgagcttg tccatttggt aacggatttt gctttttcgg atgacagttc
     1081 aataagcttt gattcgccga cttttaatgt gagcgaatca accttgctcg gaaatgtcgt
     1141 attttcggtt actgccgtat cgggcgtctg cggttttgga gaattttgag aatcatttcc
     1201 gaaaattccc gtcagaccgc ataatatgca ggttgcaatg aggacaacac aaagtaaaag
     1261 aatgaaaatt ttctttttca tagattacct atccttatag aatttaacat taaatggtta
     1321 caaaatttta acctttgtat attataactt tttttcgaca atcttgcaag tgctatttta
     1381 aatcggcaag aaatgtggta aaatgtcagt cggagaatgt tttgtatttt ccaaactaac
     1441 aatttatggt gataattatg gcacatccga ttaaacattt cagaacaata acccgccaca
     1501 ggcacaaggt aattgccaac tgtgcaaggg caggaattct cagacaggga ttaatacacg
     1561 atttgtcaaa gtattcgccc acagaattta ttccgggtgc aaagtatttt cagggcacga
     1621 gaagtcctaa tgaaaaggaa agagagctgt acggctattc acaggcgtgg ctgcatcaca
     1681 agggcagaaa ccgtcaccat tacgaatact ggaacgatta caacccaaag acaaagcaga
     1741 ttgaaaatgt tgaaatgcct gtaaaatatg ttatcgaaat gttctgcgac cgagttgccg
     1801 caagcaaaat ctacaacggc aaaaattaca cggacggcgc tccgtttaca tatttttgca
     1861 gaatcagagg caaacaccgt atgcacccca acaccgaggc tttgcttgaa aaattattgg
     1921 ttatgctgag agatgagggt gaagaaaaga cctttgcata tataagaagt atgaaaaagt
     1981 gattgtttgt gcgaatcctc ccgtctgaaa tatagtcgca aggctacccc tacagaattg
     2041 cacaaacaaa aaaactatct acacgaatag ggtacggcgg ctcgccgtaa ggagtgataa
     2101 tatgaaaacc gacagggtta taactgctat gattgaatat tttggaagtg acaagaaaag
     2161 aattcaccat tttctcaagg tttattcatt cgcaaagaca atcggtgaaa gtgaaaatct
     2221 tttgcccgac gatcaggagc ttcttgaaat ctccgcaatc gttcacgaca ttggcataaa
     2281 ggtgagcgaa gaaaagtaca attcgtctgc aggaaagtat caggaacttg aaggtcctca
     2341 cgaggctgaa aagttgcttg ccgctctcgg ctacgaaaaa acatttattg acaaagtttg
     2401 ttaccttgtg ggacaccatc acacctatgg aaatattgat actttgccgt accgaatttt
     2461 ggtagaggca gacttccttg tgaaccttta tgaggacgat tcaagccgca gtgcagcaga
     2521 gcaggcatat gacaaaatat tccgcacaaa tacaggaaaa aatctgctga aaataatgtt
     2581 cctcataccc taaaattgta ctcatttacc atagtgtttt gagtgtgaaa aagtggtgta
     2641 aaaagtatct caaaatgctt gacaacgccc ttaaaaagtg ttattttaat ggtgttggtt
     2701 atatgattat aaaagtgaat aaatgacaga atacaaggat gtatgacgat tttttcaagg
     2761 agctgacctt accgggcgtc tgcttggaat tgagtcggca tttttttgtg tcatatacaa
     2821 aattcagtat taattatcat tatcggaggt tttacagtaa tgagagaaga atggacaaat
     2881 tttgcaggtg gcaaatggga gtccgacatt gatgtcagag acttcattca gagaaactac
     2941 acaccttatg acggcgacca gtctttcctt gaaggtccta cagaagctac agacaagctc
     3001 tggggcgagc tcaaggaact ccagaaggaa gaaagagcca agggcggcgt tcttgatatg
     3061 gaaactgagg ttgtaagcgg catcacagct tacggcgctg catatcttga taaagacctt
     3121 gaaaaggttg taggtcttca gacagacaag cctctcaagc gtgcatttat gccttacggc
     3181 ggtatcaaaa tggctgagca gtcatgccag atgtatggct acactccaag ccctaaactc
     3241 cacgaaatct ttacaaaata tcacaagact cacaaccagg gtgtattcga tatctacact
     3301 cccgagatga agcttgcccg tcacaacaag attcttacag gtcttcccga cacatacggc
     3361 agaggcagaa tcgttggtga ctacagaaga gttgctcttt acggtattga ccgtcttatc
     3421 gaaggcaaga aagaggactt tgcagaaaca aaccgtcagg gtatgagaag aggcgacttc
     3481 cagcttcgtg aagaaatcgc tgatcagatt cgtgctctta acgatatgaa ggaaatggca
     3541 ctttcttacg gctttgatat ttcacagcct gctaagaacg ctgcagaggc agttcagtgg
     3601 ctctacttcg gttatcttgc tgctatcaag actcagaacg gcgctgcaat gagcgttggt
     3661 cgtgtatcaa cattcctcga catctacatc gagcgtgacc ttgagaacgg tacacttaca
     3721 gaatcacagg ctcaggaact cgttgaccac tttgttatga agtgccgtat ggttaagttt
     3781 gcaagaattg agtcttacaa ccagctcttc tcgggcgacc ctgtatgggc tacactcgaa
     3841 gttgcaggtc ttggcattga cggccgttca atggttacaa agaacgacta ccgtttcctc
     3901 cacacacttg agaatatggg accttcacct gagccaaacc tcacagttct ttattcttca
     3961 agacttccgg agaacttcaa gaagtatgct gctcatattt cagttacaac aagctcaatt
     4021 cagtacgaga acgatgatgt aatgcgtcct gtatggggcg atgattactc aatctgctgc
     4081 tgcgtatccg caacacagac aggtaaggaa atccagttct tcggcgcaag agctaacctt
     4141 gctaagtgcc ttctctacgc tatcaacggc ggtattgatg aaaagacaaa gatgcaggtt
     4201 ggtcctgaat atacacctat cacatcagag taccttgatt atgacgaagt tatcaagaag
     4261 tatgacacaa tgatggattg gcttgctcac ctctatgtag gcacacttaa catgattcac
     4321 tacatgcatg ataagtacta ctatgaggca gcagaaatgg ctcttatcga tacagatgta
     4381 agaagaacat ttgcaacagg tattgcaggc ttctcacatg ttgttgactc actcagcgct
     4441 attaagtacg ctaaggttaa ggttatccgt gacgaggacg gcattgctgt tgactttgaa
     4501 acagagggcg acttcccaag atacggtaac aatgacgaga gagcagataa gattgccgtt
     4561 gatcttctca agacattcat ggctaagctc aagtattgcc acacatacag agattcagag
     4621 cctacaactt ctatccttac aatcacatca aatgttgttt acggtaaggc tacaggttca
     4681 cttcctgacg gcagaaaagc aggcgagccg ctttcaccgg gtgctaaccc aagctacggt
     4741 gcagagcaga acggtcttct tgcttcactt aactctgttg ctaagcttcc ttacgagtac
     4801 gctcttgacg gtatttcaaa tactcagaca atcaacccgg gtgctctcgg acacaacgat
     4861 gacgagcgtg ttgacaacct cgtaaatgtt atggacggct actttgatca gggcgcacac
     4921 cacctcaatg taaatgtatt cggtacagaa aaactcattg acgctatgga gcatcctgag
     4981 aaagaagagt acgctaactt cacaatccgt gtatcgggtt atgctgttaa gttcatcgac
     5041 cttacaagag agcagcagct ggatgttatt gccagaacct gccacgacag aatgtaatgt
     5101 cggacaacgc tgttaaaggc tttgtacact caatagaaac ttttggctct gttgacggtc
     5161 cgggcgtgag atttgtgatt tttctgagcg gttgcgcaat gcgttgccag ttctgccaca
     5221 atcccgacac atggaaacac gatgaaaaca ccgtggaata caccgccgac gagttgctta
     5281 ataaagcgct tgcataccgc ccctattgga aaaataaggg cggtatcaca gtaagcggag
     5341 gtgagccgct tttacagatt gactttttgc ttgatttgtt caagaaggct aaaaagcagg
     5401 gcgttaatac ctgtattgac acaagcgcca acccgtttac aaccaaagag ccgttctatt
     5461 caaagtggaa agagctaatg gaatatacgg atttgctgtt gcttgatata aagcatatcg
     5521 acaacgaaca gcacaaaatc cttacaggac agccaaacac caatattctt gaaatggcaa
     5581 gacagctttc cgatatgggc aagcccgtat ggataagaca tgttctcgtg cctgaaagaa
     5641 atgataagga cgagtatctt ttcagacttg ccgattttat ccgttcgctc aggaatgttg
     5701 aaagagttga agttcttccg tatcacacac tcggtgtgta caagtggaag gctctcggtt
     5761 atgactatcc tctcgagggc attaatcccc cgacaaaaga gcgtgttaag aatgcggaaa
     5821 tgattcttaa cggcgaaaaa acaagagatt aatttcttat ataacaacgg cagtaccgat
     5881 tttttttggt actgccgttt ttgttttgat ttttatttgt tattctgctt ttgttgtttc
     5941 ttctgcagcc aaaattgatg aatcaaaggt gtattcaaag atttttgagc tatccttgtt
     6001 gagaaatcat cacagtcggt tcagactgct ccgacgggtg agcctgcaac tgtcggtaca
     6061 acctctgtaa atccgacttc ggcaacaggc ggtgccgcaa catcggacag cactccttca
     6121 cagcctgata aaaacggtag tgttcagaca ggagtgacag caacggctgt tatgatgctt
     6181 gttgtaattt cgggcggagt gctttttgcc cttgcagagc gtaaaaagag aatataacac
     6241 actgacagcc atttgtgcaa agattatcag ttgtctattg aaaaatttgt aaaaatgata
     6301 taaaatagca ataagtagaa aaatacggtt tttccgctga tttatattaa tactgaaaga
     6361 ggtgccggaa tggataaaaa caaaaaatta ttctacacaa tcatcggtgc aatctctgca
     6421 cttgcggctg ccacagcagc atttctcgct ttaaaaaagc acagatgcgc agagcagaag
     6481 cttattgagg aaattgacga tattgtttcc gaaaaagagc ctgaggaggt tgcaaaggaa
     6541 gaaccgcagg cagaagttac agccgatgag cttgctgagg aagaataagc aacaagttgt
     6601 tgcacccaat tcgggtagca gtatttgcat gtgcgaaagt taagtacccg agcggtgctt
     6661 tcaattaaga attgaaagtt gaaaacagat aatgatgtca gcggtgtgcc accgcagtct
     6721 attcaagaaa acagtttaaa aaagaaaatg catcagatgc ccgaaaaggt ctgatgcatt
     6781 tttgttttgt taggctgttt tgtcacagcc ccatcgaaat tgctcttgac gcagactttt
     6841 ttgttacaaa acaattgttg taaaaaatta aatacgatag tattattatc agttatttct
     6901 gaactgagga acatggataa gacaatattc acaataatca gacaatgaat ttgtatataa
     6961 tagcaaactt accgttaatt tgcacatatt ttagggcaaa aaattttcgc taaaagaata
     7021 acagattcat tgcccgaaca acttaaatgt gctataattt aaatgtcctc ggaaattttg
     7081 tactgttaaa gtttccgaag ctagaagtat tgccacaaaa ctgtggcgaa cggtaatttt
     7141 attttattaa aggagcagca agtatgaaaa aaattcagaa aaagctttct gtggttcttg
     7201 cggtaatgat ggtgctgtgc atgttcacag ctctgccttt ctcagcaagt gctgccgaaa
     7261 caagcgaaga aacaagtgca ggcaacaaga tcaatgttac atcaaatgtg acagatcctg
     7321 tttcgtatga ttacaatgca cagacagagc aggttgttgt tacttacctt ctcaaggcag
     7381 atcacatgat cgttgataca cagagcagtc ttacatacga cagcaaggtt ctcaagcttg
     7441 catcaacaac aacaacaaat acaaagaaaa aggttttccc tgtattccag agcagcatcg
     7501 tttggaatac aagcattaca aatcaggttt acttcaactg ctcaagcctt gatcttttca
     7561 acttcaagtc agagaatgtt tattgcacat ttacatttga tgttgtaggc agcggtgaca
     7621 caacagtaaa tctcaatgtt gattatctta caggtacaga ggctgaatca tatgatgatt
     7681 tcttcgaaag tgaaaagaag gacatcgatt atatttacga tagtgctaac aaagtagaag
     7741 gtgctgcatt tactgcaaag gcagttctcg ttcagggcga agagccaaca acagttcctc
     7801 agcctgcaac agagccgaca cagccacaga gcggagtaag tgtaacagga gatatcgcac
     7861 tcccgcttgc agatgacggc aacggcattt atacaggctc aactgaactt gaagcaggtt
     7921 catacacatt caagatgagt gtaaacggag ttgcattcgg taacggttca acattcacag
     7981 ataaaacaac aaacgcaaca tacagttcaa agtggaaaag ttctacaacg cttaaggcaa
     8041 caggcggtaa gtacacattt aagtttaata ctgcaaagaa tacccttaca attgaatatc
     8101 ttgcaccttc aaaggcttca atagtcggcg atatcaacct tgatcttcag gcaacaaagg
     8161 atgcaaatgt ttattcggca tcagttaagc ttaacaaggg caactatgaa ttcagagtaa
     8221 tgaatcagga tgttcgttat tgttgcggtt acacatacaa ggactttaca gtcggaagcc
     8281 agttcagctc aaagtggtcg agtgcgtcaa cgcttgcagc atcaggcggt acatatacat
     8341 tcagctatga tattgataca aacaagctta caatatcata tcttccttca ggagcagaag
     8401 taagtgtagt aggtaacttt acacttgccc ttgcaaagac agataaagaa aatgtatatt
     8461 caggtacaaa gacacttaag gcaggaaaat atcagataaa gatgaataac tacggcaagc
     8521 tctgcggaac atcagcggta gtaaaggatg caacaccggg tcttgtattc agtccaaagt
     8581 ggagcaagta cacaacattt gtagcaacag gcggaacata cacattcaca tacaacacag
     8641 caacaaataa acttgtagtg acagcagata agggagatat tccggtaaag gtaacaggag
     8701 atatcaacct tacactcaag aagagcgata caaatgtatt tacaggttcg gtaaagctta
     8761 aaaggggtga ccactcgttt aagatgaatg ttaacggtac agatttctgc agcggtgcaa
     8821 caatcagaaa tgcaacaaca ggtactgtta agtacaactc aaagtttaca agtgcaacaa
     8881 cacttgtagc aattggcggt acttacacat ttacttataa tacacttaca aatcagcttt
     8941 ctgtgaagta ttctaagtaa atcggcttag catcaacaga atataatttc aagcactccg
     9001 cacatcagtg tggggtgctt ttttttgctc aatatcaata gttagttggg ctaacccgaa
     9061 aaaacggaat ctgcgcttct tgagaaacaa atttttcgaa tgcaggaatg atcttgatta
     9121 tatgtttccg ataatcgtga atattatcag tgtgttttcc acacacagga tattcgtgca
     9181 tttttagttc aagcttgcag taaatatgaa tggtgctgtc aatttcttcg atgttttaaa
     9241 ttaaaatgtt ttgcaatgcc aagcgttttt ctgtaaaata tctttagagc atatttttcc
     9301 tccgtttcag gtttttaagc aattccattt taacggattt tggtaaaata agctctactt
     9361 ttttgctttt catttgtagg cttttttcta cccaaacttt tattatagag ccgaaataaa
     9421 taatattgca aaaatcagta aaataatacg catactcagt gtaaattgca ccgaggatgc
     9481 gtttcttgaa ttattgatat ttaaagttct tctctgactt ttttaccgtt tcgttttaca
     9541 atatatgccc tactgccgac aacaacacaa tctgaaggga catctttaac gattattgct
     9601 cctgcaccga ttatgacatt gtcaccgata gtaacatttc cgagaacttt tgcacctgtc
     9661 attattttaa cattgtttcc gatttttggt ctgccttttt ctgtgtgacc aaccgtaact
     9721 tgctgattta tccaacaatt acttcccata gtttcaaccc ctacaattgt agaaaatcca
     9781 tgttgtataa ataagccggg tcccatattt ttactggtta agtacagcga atccaagggc
     9841 ttgcaaaaaa ttttcaaaaa atattttata tttccaagac gcagataaaa tacatttctg
     9901 aattccttaa aatgacacat catatagaaa aataagtatg tataactgca attgtttttt
     9961 ttaggacaaa gttttctcca actttcaaga tccttgcata gaacatcgtg tttttcacag
    10021 agtttaaata caaagaaatg cggaagaaga aaaattgagc gtaaggcaaa taataatttc
    10081 ataaatcctc ctgaggttca ataatcaatg aagcttggat accttgtttt ttaggctata
    10141 aaacttcatc tttattcatt attcttcttt tgattttctt tattataatt ttgttgtaat
    10201 attttttaaa tgtcttttca aaaccgtttt tataatagaa attccagaaa tcttctcgac
    10261 tgtcgggttt tgcggtaggg catgacagat tagggttaga ctttattgaa gcgttaaggt
    10321 cacattctac acaatgaata ttgccgatta ctttgttgag aatacgagat cctttttcgg
    10381 aatttaccaa caataaagaa actcccttgt tgtcattgaa attttcaact acacggtcga
    10441 ttccccagaa gtcagcaagt gtgagatcgg cgggtctatc aatgtttgaa tacttacaat
    10501 tatagcagga tggacgctca atatcgtctt cgtagaatag atatgtgtag ccgttaagaa
    10561 tatgcttatt gtcatcaatc caaatcgctt ccttgtgggt attccagcct atagttttat
    10621 cacgaaaatc tgccttggtt acttttccgc aaaacttttt ttcacaatgc ttgaggtact
    10681 ctttccatat aataggagag ggaactccgt gacaggcaat gtcacatgta tagagttttg
    10741 aggtgtcgca tttaccaaga tatcttttaa gtccggcaac ttgacaggct gttccggaaa
    10801 acatgacata catatcgtta tttaaatcat ttttgacaga tttaaatgtg tctttcatat
    10861 cgctctggac atattttgag cccttaaact tatctctgac ataacgatcc gttgctctta
    10921 tgtggctgac tgagaaatca tcctgaaacg cagcaccgta aacagaacct tttttattaa
    10981 gaatataatc ggataaggct ataaatgcag caccgctgcg gcttgtaaag cgagtattaa
    11041 agtctttatg cttgattgca tatgctgtct ttgaatggtt cttttcataa ccgttctgaa
    11101 atgcgcatat tttttggcag gcgccgcatt caatacagag tgagacatca atttgtgggt
    11161 agagaaaacc ttctgaatca ggcttcatag ctatagcgcc tttaggacat atctgtttac
    11221 aggctgaaca tccgcagcat tcactttttg aaggaaaaat ctgcatattt attccccttt
    11281 aattatatct ttaaggtaat caagcgagtg tttgcgctct gcttgaagta tgttatcgac
    11341 tttattccag tcaatatctg ttgtaacggc ttccccgtct ttaatttctc ggtttatgcc
    11401 tattgtctga agaagatttt ttgcacggtg attaaatcct tttgctgttt catattcaac
    11461 aaacatattt ttgtgaaaaa ttacagaaaa agcagttccg tgaaatgaat tggttaccgt
    11521 ataatctgcg tttgcaaaat aaccaagaaa ttcttcaact gttggggcag atacataggt
    11581 gaaattttta cgcttttttt gtggattatc tgttatataa acaacgggaa ttccggtctt
    11641 ttttgaaagt ttttccgcaa aatctatcag tgattttaca ggttttacat taaatacaag
    11701 aatatatggc ttatcaattt tttttacaga aatcttttgc cattcatctt tgttcagaag
    11761 aagtgtaggg tcaatatgac acacaccgtt cttaccggtt atcttcttta caatatttaa
    11821 tgcgcttttt tcacgaactg aaaaagactg aaaattttta agtaaaggtc tgagctgcat
    11881 tgcctttaca tcgcttatat ctgcaacacc aaaacttgct gcataactgt atttttggtt
    11941 atcgtctgca aagctcagaa aatagatgga atcaggattt attccttcct taccgggacc
    12001 ccacacctga tcgcttccgc tgatgaaagc atcataaaga tttttgcatt ctgatatatc
    12061 cgaattacta taggttttat tgctgatttt aagataattg ttgtagaagc ttgaaaactg
    12121 ttcaattttt ttagctctct tgcgatacat aacaatggat ttcaaaattg acttaatagg
    12181 atcagttttg ctaaactgaa acggtttgta gccattgtcg atattttcac atttataatc
    12241 tacgatttca cagtcacttc caagctgttt aagggtgtgt tgaagtgcat acgcctggag
    12301 aacagcgccg taatttttgg cacgatgaaa agtaattatt ccaatttttt tcatatccgt
    12361 taaatctcct tatgaatgct tgtacagcag gtaaccaata gggcttgtta ggagaacgag
    12421 caatctgcgg ggcttagtct tgagcatagt caatatttca ctaagtttgt agccgtttgc
    12481 aagtccatca cgggttattg ccacgatgtg ttcaaggtaa cgctttcgat tgtattttct
    12541 gtaatcccaa cagtcattta tataatgcag atgcatgaca aatttttctt ttgatgcctt
    12601 ttttctgttg acatttgtaa cagcattttc ctgatcttga atatagtatc tcaatgctgt
    12661 gcttaaatat ctgcatatat attttcttcc gacattatgc cagataacat tttccgggta
    12721 gaagtgatag ccttcgacaa cagggaatgg aaattcacgc ataatatcgg ttctaatcat
    12781 accccataat tcccctgtga tattgagttt aaaacgcaaa tcaaggtcat tgctgtcaat
    12841 atacggaaca ttcatttgtg ttccgttaat tttaccatcc ttatcatatg tacggcagga
    12901 tataccgtaa tatttttttt gctcctgttt aggaatttta ttccattcat ttacaaatgt
    12961 ttcaagggcg tcatttgtac aggtatcatc agagtcaagc gtaatgaaaa agtttcctct
    13021 gcacattttt acagcattgt ttgtggctat atgcttgcct tgattttttt gataaacata
    13081 aataatgtca aaaaaattat tttctttcag aaatccgtcg acaacatcct ttgtattatc
    13141 ttcactgccg tcatctataa ttatccattc aaagctttta taggtttgtt ttttcaaaca
    13201 ttcaaaaact cttggaagag tttttgcacg attataggat ggggtaaata cagttatttc
    13261 aacattactc ataattaact ccatttcatt tttttgtaag cttatttttg agcttgcaaa
    13321 gttccgcttt attaaataac aacggcaagg acaaggcata tgcaaggatt ccgcatatag
    13381 cacatatgaa tataaatgaa ctccaaccgg ttactgtaat taaattgctg ataattgaga
    13441 ataataccaa tataatgata aatccaacac aatctcggat tactgtcggg aaaaatattg
    13501 aaagtttttg ctttagtatg tatgcagaat atgcaggggt aaagatgagt gcacgcagtc
    13561 ccataagaac ggaactcgtt cctgctacaa aatatacgcc atagtcggtg aggttacagg
    13621 ctgcaattgc aactataacg ctgacaatgc caactgtaag gtttacaaat acaggtaatc
    13681 taagtttatt acatacggtg tttatcatca taagcgactg agtttgactg gaacaaagaa
    13741 atgtaataca agtcaacacc gacataaact gaatcattgt aatctcctcc ggtgactttg
    13801 tcggttgcca taatatgtag aactgtctgc caaaggcaat aaaaccggca ataggagtcg
    13861 agagtataaa gcttacaatt ttggtactga atttcgcctc gataattagc tccggtattt
    13921 ttttctttgc ataaagaatt gtgtaatgag gagtaaatac tgaacctaaa attacagtta
    13981 ggttgccgat actgttcggt acggtttttg cgatagagag aagtcccatc agtgccgttc
    14041 caagggttag gttgcatatc agaagatcaa gaccgcttag aagcacctga caaagttgtg
    14101 caagtgaaag ccaaatgccg gacgcaagaa gtgttttaac tattttaatg tcaaattttc
    14161 taatatcagc ctttacttcc gggagtacct tctttttaac agtaatattt gccagcaaaa
    14221 ggaaaatacc gcttccaaaa cttgcaaggg taacaaagta aagctgtgca gggaaaattg
    14281 caaataaaag tactatgagt gcaactttta taaggttgga tataatatct cgtatagaat
    14341 ttatatcaat tctgtttttt acaaaggctg ctgttgtgaa aatagcagta actgtgctga
    14401 caacaaatgt gagaaaagca aaagcaaagg ttatttttac gccggataca agatttgaag
    14461 gtattttaag cacagtgtca agaaaacaaa caaaaattga cgacagaatc aacattactg
    14521 cagcgaggaa caaatcggca acgagaaccg aactgaatat ttttgatgat ttctcaacat
    14581 cgcccttatg gtatgcaatc gaaataaatc tgcctgaaat tgaattcaaa gcggttgtaa
    14641 cgatggtagc atactgtaca aagttattag caagaccgat aaaaccatag gcatcactgc
    14701 cgacctcttt tacaagatac ggtgtcagaa aaaagttaat tccaacagta actgcaaatg
    14761 aaacgatact tgcaattatg tttatcgaca tttgttttcc ggcggatttt ggcattaaac
    14821 ggtcacctct gaagattcgt tctgtatcag ttcctttatt ttgtttatat attcctttga
    14881 tttatttctt tcctttaaaa gtacattgtc aaccctttcc caattaaccg caccgtttat
    14941 atttggaaaa acatcatttg ttatctcgcg atcattgatt ccaagattgt taagaagttc
    15001 ttcagcacgg atgtttctgc caccgatatg ttgcaattca actgcaaaat tctttttata
    15061 gattaccgaa aaggcagtgc cgtgaaatga atttgtgcaa atatattctg cgttttttat
    15121 taaacctaca aattcagtgg cattcaccgg atcgaggtac tctataccgt caatcttatg
    15181 gagcctctcc ttttgcaggt agtagatttt gtatccggtt tttttagaaa gttcaagagc
    15241 gtagctgata agtttaattg gctttcttac gctgaacaga aaaatatacg gttcttttgg
    15301 tacaggacat ctgcttattt tatcccaatc atcttcagta agcaacaacg agggatcaat
    15361 actgatttca gcttttctgt tgataagatt ttcaataata tctgctccgc ttttttcacg
    15421 aactgaaaag agctgaaatt gtgataacaa ctctttatat gtatgttcct tatcagcagg
    15481 aagcttatca actgcaaagc ttgccgcata ggagtatttt tgctttggtt ttgcaaaatc
    15541 aagtaaatat accgtatcaa agccaacgca gatgggactc cacacctgat cgctccctgc
    15601 aataaatgct gcatattcat tggaggcttc cccaatgttt ttggcatcaa aaggacgact
    15661 gaggtttaaa aattcgtttc tgaatgtaac ggactttttt ctgtcaattc ctacttgacg
    15721 catagtgatg agtgaacgga taaatgactt caacttatga tgcttgccta cgcgaatagg
    15781 tcttatgttt cttgtataca taaaatgaca tgtgtagtca attacatcat tttctatgcc
    15841 gtttttttcc aa
//
