LOCUS       gnlProkkaCAKCHGEE_13   14892 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CAKCHGEE_13.
ACCESSION   gnlProkkaCAKCHGEE_13
VERSION     gnlProkkaCAKCHGEE_13
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 08:29:27
            Original ID  :: gnl|Prokka|CAKCHGEE_13
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14892
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14892
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4541:4892]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4542..4892
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14892
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14892
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..1112
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 315.7; E-value:
                     9.2e-96)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg13_1"
                     /transl_table=11
                     /translation="MGVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEK
                     GAFTGAIGERKGYFGEADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTD
                     VRVVAATNVNLTQAIAEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEK
                     YRMPAIQLTEDAKKELLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQ
                     RLPALMGTRESKGFESEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTV
                     VTTPVVTAHQPSVPAIIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALER
                     HHGKRKSAAKDLNISERTLYRKIKEYELD"
     CDS             complement(1132..1596)
                     /locus_tag="ctg13_2"
                     /transl_table=11
                     /translation="MVGDLFRHFSNQSVLYGSQQLARVVGTERRKLLFKVFGMIGVVDK
                     TYINGDSQLRLRRITVGRYSLIVLIVTCDFSVNLQVGILTRLEQLQTGLPDEDIFQVLI
                     KLGCQRSIHILRLDREVGYRNGLYLIIIDRRSVKLIGNSARNDYQRQAEQ"
     CDS             1632..2405
                     /locus_tag="ctg13_3"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQPAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             2412..2807
                     /locus_tag="ctg13_4"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             3056..4444
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg13_5"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             4542..4892
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_6"
                     /sec_met_domain="PqqD_RRE (E-value: 2.7e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9.8e-18, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVVPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(4911..5195)
                     /locus_tag="ctg13_7"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(5232..6299)
                     /locus_tag="ctg13_8"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVSKKVAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVCLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             complement(6372..7883)
                     /locus_tag="ctg13_9"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASILAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             complement(8158..8274)
                     /locus_tag="ctg13_10"
                     /transl_table=11
                     /translation="MRNTLKYYENKVAFEPKYGRTYEKYRFEKVFLIRYLFD"
     CDS             8945..9169
                     /locus_tag="ctg13_11"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             9362..10906
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 46.8; E-value: 2.5e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg13_12"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKADHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             10947..11483
                     /locus_tag="ctg13_13"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             11543..12112
                     /locus_tag="ctg13_14"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             12376..13365
                     /locus_tag="ctg13_15"
                     /transl_table=11
                     /translation="MLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAE
                     TGEYLCDVTEDGQEVVLLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLL
                     ADVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGII
                     EGASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVL
                     AVTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIV
                     HRPKDVTRLQQELKDMGEDEDIVYEYEEDVDDDDDIDYEYEEEDWEEK"
     CDS             13362..14174
                     /locus_tag="ctg13_16"
                     /transl_table=11
                     /translation="MISLTKHNELKGYKSLEAYPEVAHFVTTRHEGISTGAYGSFNCSP
                     YTNDSCMNVNRNQSWLFQCMNHQIKELFIPEQNHGCASLIINESFFKESLEMRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSNVMDHLNKMF
                     GTQGEDVIACIGPSISLESFEVGDEVYDAFEESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNLGVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRTLSGIMIRK"
     CDS             14225..14890
                     /locus_tag="ctg13_17"
                     /transl_table=11
                     /translation="MFEIKVSKEIKDACPVFAGAAVYAAVKNTAYNEGLWQEIDAFTRQ
                     LTSTTQMEDIKHQPVIFATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGTHLELGIGKAGEPFEGIGRGVLNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDLETTHILAIVNGYNGKEGLREAAEMIQTLLRNYTESDGGEIVFFE"
ORIGIN
        1 aaagtggagt cggaaaagaa agttttccgc agattattca tcaatatagc cggaggaagc
       61 acggacagta tattgctgtc aactgtggtg ctattccgga gggcacgatt gattccgaac
      121 tgttcgggca tgagaagggt gcgtttaccg gtgcgattgg cgaacggaaa gggtactttg
      181 gcgaagctga cggtggtact atttttcttg atgaagtagg ggagttgccg atgtctaccc
      241 aggcacgttt gctccgtgta ctggagagtg gcgagtttat gaaagtaggt tcgtccaaag
      301 tacaaaaaac ggatgtgcgt gtggtggcgg ctaccaatgt caatctgaca caagcgattg
      361 cagaaggacg tttccgtgaa gatttatatt accggttgaa tacggtgcct atccaaatac
      421 cgcctttgcg tgaacgtggt gacgatgtac ttttgttgtt ccgtaagttt tccgcagact
      481 ttgcagagaa ataccggatg cctgctattc agttgacgga ggatgcgaag aaagagttgt
      541 tggcttaccc gtggcccgga aacgtgcgtc agttgaagaa catcaccgag caaatatcta
      601 tcattgaaac caatagggag atctctgctg ctatcttgca gaattatctt cccgcacaaa
      661 atacgcaacg tcttcccgcg ttgatgggaa cgcgtgagag taaaggcttt gagagcgaac
      721 gggagattct ttattccgtt ctgttcgata tgcgccagga agtggcggag ctgaagaaga
      781 tggtgcacaa cctgatggcg gaacgtgccg gacaggtggg gcaggtagga caaatgggaa
      841 cggtggttac tactccggta gtgacggcgc atcaaccttc ggtacctgct attattcaca
      901 ccatgcagcc tacggtttgc aaggatgatg atgacataca agacacggaa gaatatgtag
      961 aagaatctcc tttgtcactg gacgaagtgg agaaagaaat gatacgcaag gcacttgaga
     1021 ggcatcatgg aaagcggaag agtgcggcca aggacttgaa tatttccgag cgtacacttt
     1081 atagaaaaat aaaagaatat gaattggatt aagaaaataa tacgcccttt gttactgttc
     1141 ggcttgccgt tggtagtcat tgcgtgcact gtttcctata agtttaacgg atcgtctatc
     1201 aattatgata aggtaaagac catttcgata gccgacttcc cgatcaagtc ggagtatgtg
     1261 tatgctccgt tggcaaccaa gtttaatgag gacctgaaag atatcttcat ccggcagacc
     1321 cgtctgcaac tgctcaagcc gagtcaaaat gccgacttgc agattgacgg agaaatcaca
     1381 ggttacaatc agtacaatca ggctgtatct gccgacggtt attcttcgga gacgaagttg
     1441 actatcaccg ttaatgtacg ttttgtcaac aacaccaatc atgccgaaga ctttgaacaa
     1501 cagttttctg cgttccgtac ctacgactct agccagttgc tgactgccgt acaggacgga
     1561 ttgattgctg aaatgtctaa agagatcacc gaccaaattt ttaatgcaac tgtagcaaac
     1621 tggtaatata aatgacttct gttaactttc aacaatggat tcagcatccc gagacgctga
     1681 atagggatac tttgtacgaa ctgcgcaatc ttcttgcgag gtatccgtat tttcagtcac
     1741 ttcgtctgct gtatctgaag aatctgtata ttctccatga tattagtttc ggtggagaac
     1801 tgcggaaagc agttctttac attgcagaca gacggcagtt gttccggttg attgaaggtg
     1861 accgctatga tgtgcaagca cggaaaaagg gagtacctct cacggaggta ctgaaagacg
     1921 aaccgtccgt agaccgcaca ttagcattga tcgacgcttt cttgtccaca gtacccgaag
     1981 aggtgactgc ccgcaccagc ttcgactatt cgatggatta tacctcttat cttttggagg
     2041 agactccggc cacggaacag ccggccgaag aaacgcccaa actcaaaggc tacgaactga
     2101 ttgacgactt tatagaaaag agcgagagcg actctcccct ctgcaagaaa cctttaagag
     2161 aagaaatgcc atcttcgcca acctcttcgg acgaacttac cgaagaagaa acgatgaagg
     2221 aagaagagga agatgacagc tgttttacgg aaactttggc aaaaatctat gttaaacagc
     2281 aacgatattc aaaagctctt gaaataatta aaaaattaag cttgaaatat ccaaaaaaaa
     2341 atgcttactt tgcagaccaa atcagatttt tggagaaatt gattattaac gctaattcaa
     2401 aataactaaa aatgtactta ttattcgtta tcttaatggt tattgcagcc ttgttgatgt
     2461 gtttcatcgt gctgattcag aactcaaaag gaggcggact tgcttctggt ttctcttcat
     2521 ctaacgccat catgggcgtg cgcaagacta cagattttct ggaaaaagca acatggggct
     2581 tagctatctt catggtggta atgagcattg ctactgctta tgtagttcct cgctctgctg
     2641 ttgctaaaga cgcagtgttg gaacaggcac agaaagaaca acagactaac ccgtataact
     2701 tacccgcagg tacggctgcg ccgcaaactg aagctcctgc taccaatgca cctgctacag
     2761 aaactccggc accggctact gaaactcctg ctcctgcagc agagtaattc actccgttgt
     2821 caggtaagac tttggggtaa aaccattaat gggaaggtgc agacggatgc tgcatttctt
     2881 tgatatttaa gtgcggatta cgcagattac acggattttc aatcttccgc gtggtcagtg
     2941 taatccgcac ttaacttttt cttgtaaaaa caatctcttt ttgatagaaa caaacgagat
     3001 ttaactacct ttgttggtcg tatgaagatt attaactact tttttaaata taacaatgac
     3061 agaacatttg aaacagaaat tgaatgactc cgccgtactc cgatggagtg ttctagcatt
     3121 ggtcgcattt actatgctat gcggctattt cctcaccgac gtaatgtctc ctctaaaacc
     3181 catgcttgag aaagaactac tatgggacag tcttgattat ggtttcttca caagcgctta
     3241 cgggtggttt aatgtattcc tattgatgct gattttcggt ggtatcattt tggataagat
     3301 gggagttcgt ttcaccggaa tgggagcttg cttattgatg gtgtttggtt gtggattgaa
     3361 atactatgcg atttctacta cttttccgga aggtgccatg ctcttcggat tcaaaacaca
     3421 ggtaaccctg gctgcattgg ggtatgctat cttcggtgta ggtgtggaaa ttgccggtat
     3481 cacagtttcc aaaattatcg tgaaatggtt caagggtaag gaaatggcat tggctatggg
     3541 acttgaaatg gctacggcac gtatcggaac aactctggca atggtgctca cggttccttt
     3601 ggccgacttt ttcggatcta cggatgagag tggcacattc cataccaata ttcctgctcc
     3661 gattttgttt tgtctgatta tgttgtgcgt gggtacgatt gctttcttcc tttatacttt
     3721 ctatgataag aagttggatg cttctttgga tgcagaggga ttggaaccgg aagagccgtt
     3781 ccgtatgaaa gatattgtgt atatcattac caataaagga ttctggctga ttgcattact
     3841 atgtgtattg ttctactcgg ctgtattccc ctttatcaag tatgctgccg acttgatggt
     3901 gcagaagtat aatgtggatc cgaagttggc gggaacgatt cccggattgt tgccgattgg
     3961 tgcgattatt ctgactccgt tgtttggctc gctttatgac cgtatcggta agggagctac
     4021 gttgatgata atcggatcag tgatgcttat ttttgtgcat acgatgttcg ctctgcctat
     4081 actgaatata tggtggtttg ctactattat catgattata ttgggatttg ccttctcgtt
     4141 agtgccttca gctatgtggc cgtctgttcc gaagattatt ccggaaaaac agttgggtac
     4201 agcatacgca ttgattttct gggtacagaa ctggggattg atgggtgttc ctttgttgat
     4261 cggatgggtg ttgaatactt attgcaaagg tccggtagta gacggtgcac agacttatga
     4321 ctacacgttg ccgatgacta tttttgctct ttttggtgtg cttgctctga ttgtggcttt
     4381 gatgttgaag gcagagaaca agaagaaggg atacggtttg gaagaggcga atatccaaaa
     4441 gtaactggga aattcaatac ctaaagtaac aaaggaattt tgtatcaagg tgtaaacaaa
     4501 agggtatcag tatgaatact ctgaaataaa aaataagaag tatggctgcc aaagagaaaa
     4561 tcaacctgtt agaggtcgtt ccctgtcgca gtgaacatat tacagcagaa agggaagggg
     4621 agacaattgt gctctccttt ccccgtttta aatatccgtg gatgcaacgc ttccttgtgc
     4681 cgaaaggaat gtcgaaagaa cttcatgtga aattggaaga acacggtacg gctgtatggg
     4741 aactgataga tggaaaacgc aatgttcgtg agattataga aaaactcgca gaccactttc
     4801 aaaatgaaga gggctacgag tcgcgtgtat cggcttatct ttctcaaatg cagaaagatg
     4861 gatttataaa actggtgata ccagtcgtat aaataggaac ttattattat ttatttgata
     4921 aatacagccc aaagtatgac ggcaattgct atcaggaccc ccatgataat aagcgttccc
     4981 caaacaaaat aattgctgtc tttctctttc tttttctccg agtcgtggat gatacgttcc
     5041 atttcttcgg gggtggtgtt gggtagtgga taaggttcgt ttgcacggtt tagatgcttc
     5101 aacttatcgt tagcacgttc acgacgtagg cgggaagctt cccgtccctc ttttattcgg
     5161 cgtatcatgt cgaatgcatg tccttcacca accatattct ttgtttttta gaagttcact
     5221 tcctcgtttt tctatttccc ttcttctctg tccactttga gcaatcctcc cgtattcgga
     5281 tcaaaataaa ctttgatggt agaattcttg ttgaacaaaa ccggagccag atattctatc
     5341 acaccgaatt gggtaatagg aagctcacct tcgtaaagtt tctttttacc gtcggtcagt
     5401 gtaaccatag cttgtccggg tacgttgtag gcgattccat ccaaatcttt cttcttctta
     5461 ccgtcttctt gtggtatctt gaccgatttc aggtctttca gactgatata aaacggagtt
     5521 cctgccaaat cattgttggc aactacacct aacttcttcg agaagcggaa ggcaacttca
     5581 ttgttgaatt ccttgtcagg ggtaaggcag acagtgaatg ttctctcttc tttgttgcag
     5641 gtgccggaga acatttgtgt catggcttct tcctgtgcat tcagattgtc gagcataatt
     5701 ttaagctgtg ccccatctga aggcatatta tcagcttgtc cgcgcaataa ggcatttttg
     5761 ctttcgcgga tgttatagat ctctttagcc accagctcgg ccatcttggc ggtagaacta
     5821 gccatcagaa tctcttcggt caggaattcg cgaggattcg ctttcttttg gaggactgcg
     5881 ggagcgggag caactttttt gcttacactg ctgttgctgt aaggaacatt gatcgttttc
     5941 acaatgccat cctctgtcag ttccatgagc ggtgctactg tcttatcctt caattttacg
     6001 aaatacgtag tttcgctgtt gggcacacct acggatttca cttttacgct agccagttcc
     6061 cagtactctt caggatcggc ggagacgttg gtcagtcgca ggtaacgatc agcatatttg
     6121 ctgaattctc cgggagtata gttgactttg ttggctttta tttcaagttc tatttgggtt
     6181 ttgggaagac tgtaaaccac tccatagtct tttcctcggg taacccccgt cagtacttcg
     6241 gtttgtgcat aggcggacgt tgtcataagt agtcctgctg ctataatcaa ctttttcata
     6301 ttcggttctt tttaactggt tttgaaaaca aagttaatga agttattgaa aaaactgtaa
     6361 gttcttaact tttattcgct tacaagtcgc catgctgtcg gcagacaggt gataatatcg
     6421 cttgcgatca ttccgatcat tccttgcttc ttttgagcga catcgcccgc caatccgtga
     6481 atgtaagtgc cgattttagc ggcttcctcg gtggggtaac cttgggcaag cagcgccagg
     6541 attactccgg tcagtacgtc accgctacct ccggttgcca ttcccggatt tccggttggg
     6601 ttgaagaaac atttaccttc gggggtgata atggcggagt aggctccttt taaaataatg
     6661 tgaacatggg cggcacgggc cagttcgcaa gccttcatca gacgttcgta agagtcctgg
     6721 catttgccgg tcagacgttc cagttctttc ggatgcgggg tgaggatgga acccttcggt
     6781 aggtgggtaa gtgcatgacg gtggttggcg aggatattaa gtgcgtcggc atccactaca
     6841 acaggagtct ggcagtgttc cagttgttcc aacaaggcag cttccgtttc ctcgtttcgt
     6901 cccagccctg ggccgatgcc gactgcttga tagtcgtccg tatcggtagg tacggcaaaa
     6961 caggtttcgt tgatatcggt ttctacgatt gcttcgggta tggaggtctg caagatgtcg
     7021 ttgttgcaca ttggtgcatg aacagtcagt aaccctactc ccgaacggag gcaggcgcgg
     7081 gcagcgagaa tagaggctcc tgccattcct tttgaaccgg caatcaatag tgcatggccg
     7141 aagttcccct tgtgggcaaa ctgtttgcgt ggcttgatga gtgaacggat ttgctctatt
     7201 tccaacattt cgtagttcgt ttccatctct tcaatgccgt cttcgctcaa ttggatatcc
     7261 aacaattccc attctccgac aaattccgtg ttctctgcga aaagaaaggc gagcttcggc
     7321 agttgcagac tgaaagttac gtcggcacgg ataatattag cttttacgtt gaatgtgttt
     7381 tcttctccca tcagtccgga aggaatgtcg atggctacta ccatggcagg ggaggaattg
     7441 atgtatttca ctacggcagc gaatccgccg ctcaacggtt tgttcaggcc tgaaccgaat
     7501 aatccgtcga ttactaggtg atcgggcgtc aggacgggag gtacgaattg ggtactgatt
     7561 tcgtggaatt ttacttcttc catcatttct accagttctt tattggtctg gcagtcgggt
     7621 gaaagttctc ctttcgtgtt gaagagaaat acctcgattt tatatccttt ttcagccatc
     7681 atgcgggcta cggcgagagc gtctccgcca ttattccccg gtccggcaaa gatagtgacc
     7741 ggcgtttccg tattccatct gtctgtgatg gcttttgtta atacggttgc tgcacgttcc
     7801 atcagatcga ttgatgcaat aggttcgttc tcaatggtat aagcgtccaa tttcttgata
     7861 ctgctgcttg gaaatatttt cattgcgatg ttcttttagt tttcggatta caaatgtaca
     7921 tgattcttct gacttttccc gtttgttgtg ggaagaaaac cataattgca acttttaatt
     7981 catcattagt tctatctttg ggtcagagaa atatctgttt ttgaactatt aagtgttaga
     8041 ataactccgc caaaaaataa ttcaatgcag caccattatg aacttacttt tatttctcct
     8101 gaaaaagatt tcttcatttc atttctcata ttctcattgt ttttcgataa acgaaagcta
     8161 atcaaataga tatcttatga gaaacacttt ttcgaaacgg tatttctcat aagttctccc
     8221 atattttggc tcaaaagcca ccttattctc atagtatttc agggtatttc tcatagtcaa
     8281 aagccatttg ttcttccttt tttctttcag cctgccttat ttttatcagg aaatgaagct
     8341 actatttaga taaaatagtg gctttttgct tgaagatgct cattggtctc gattgtccca
     8401 tatattgtgg gaaagttttc cttcaatata cgggaatact ttcccacaaa ataagggaat
     8461 actttcccaa gccttaggga atctattccc acaatatgtg gaactaagac actgtgtatg
     8521 gaagcaagca aaaggaatac atagttttat ttattcaatg tcagcttctg gcacactaca
     8581 ctatgagaaa tgaagcaaaa tccgggttat tttgcgaaga aactatgaga aatgcctgtt
     8641 tttaaatcat ttctcatagt ctatcttatt agtttactgc cacttgtttc ttatttatga
     8701 gaatatgaga aatgaaaaat ctttttctgt agaggcgcgg atggaaattg tgtttagttt
     8761 atcgccatac cttcttaaac aaatttttaa tgcggttccc ctgattaagc ctttgattat
     8821 ttgccgtttc cgataaaaat gttatctttg gagatagata atgtgcatca cattattttc
     8881 cagtgctcac aatgaaaatg aattaaaatc taaataacgg attgtttaat cttctaaagt
     8941 ttgcatgatg gaaaagacaa aaattggctt gaatgccggg aaagtatggc gcatcttaaa
     9001 tgaaaaaggt gaactttcaa tgttcgattt gtgccgtgaa ttaagtttga cgtttgaaga
     9061 cgtagctctt gctattggtt ggctggcccg agaagacaaa atctttttga ggaaaagaga
     9121 aggaatgctt tttgccagta tcgaaaatgt cgaatttact tttggctaag gtggtagcta
     9181 acctacattt aagatggatc tccactttat tatttacact gctaaaaaag taatgaagtg
     9241 gatcagtagg atttttatgc tcgtttttac tattccccct attattctgt ttgataagag
     9301 aagcatctaa tctacttttt ctgtaccttt gcaccccata aactactaaa cacataaatt
     9361 catgagtgca ttgaaagggc atccgaaagg cctttatctg attttcgcga caagcacggc
     9421 agaacgtttc agttactacg gtatgcgtgc gatctttatt cttttcctga cgcaggcatt
     9481 attgtttgac aaagaagcgg cagcatccat ctacggcagc tataccggac tagtttattt
     9541 aaccccgttg attggcggat acattgccga taaatattgg ggaatccgtc gttccgtgtt
     9601 ttggggagcg gtaatgatgg cagtcggaca attcctgatg tttatgagtg cctccacttt
     9661 agataatacg aaccttgccc actggatgat gtatggtgga ctcggcttcc tgattctagg
     9721 caatggttgc ttcaaaccca ctgtctcttc tctggtaggt cagctctacg aacccggaga
     9781 caggcggttg gatgctgcat acaccatttt ttatatggga gtgaatgtag gctcttttgc
     9841 tgctcctttg atttgtggtt atctgggtga taccggtgat ccgcatgact ttaaatgggg
     9901 atttcttgca gccggaatca tgacactgtt caccgttgtt cttttcgaga ctcaaaagaa
     9961 taaatatctt ttttctcctt ccggagaacc gattggtatt atccccgatg ctaaacgtga
    10021 aaagaaagaa gacaaggccg accatatctc acacccgaag atggacaaac gtaccaaagt
    10081 acgtaatacc cttgtaatca caattcttac cattgcttta atagccttct ttaactatgc
    10141 atttgaaggc gattgggtga gtatcggcat ttttaccgcc tgcattgttt tccctgttct
    10201 gatcctgtta gacggttcat tgacaaaaat agaacgcagc cgtattttcg ttatctatat
    10261 agtagccttc tttgtcatct tcttctgggc agcctacgaa caggcgggag cttctttaac
    10321 tctcttcgca tccgaacaga cgaatcgtga catattcggt tgggaaatgc cggcttcatg
    10381 gtttcaatcc ttcaatccac tgtttgtagt tgtcctggca tatatcatgc cgggtgtatg
    10441 ggggttcctg aacaagcgaa agatggaacc tgcttctcct accaaacaag cgattggtct
    10501 gttactcctt tctttaggtt atcttttcat ctgtttcgga gtgaaagatg cagttcccgg
    10561 agtgaaagtg agcatgattt ggctgacagg actttacttt attcatacca tgggtgaaat
    10621 agctttgtcg cctatcggac tttcaatggt aaataaattg agtccgctgc gtttcgcttc
    10681 cctgatgatg ggaatctggt atctgtctac tgccacagcc aataaatttg cgggaatgtt
    10741 gagcggactc tatccggaag ccggaaaagt gaagtcaatc tttggttatc agattgctac
    10801 catgtatgat ttctttatgg tattcgtcgt aatgtccggt gttgcttcgt tgattctgtt
    10861 ccttctctcg aagaaattac agaagatgat gcacggggta gaataaaaaa tcgtattttt
    10921 gcaaggttat ttttaaatta ccggttatgg ataccattca gataaaagac aaattgttta
    10981 ccgtttccat taaggaacaa gaaattcaga aagaagtgat tcgcgtagcg aacgaaatca
    11041 accgcgattt ggcaggtaag aatccgcttt tccttagtgt gttgaacggt tcgttcatgt
    11101 ttactgctga tttactgaag cacatcacca tcccttgtga aatctcattt gtgaagttgg
    11161 cgtcttatca gggcatcact tccaccggag tgattaaaga ggtaatcggc ctgaatgaag
    11221 acattgccgg acgtaccatt gtgatcgtag aagatatcgt agacacagga ctgacgatgc
    11281 agcgactgct cgaaacatta ggtacacgca atcccgaagc tattcatatc gcttctctgt
    11341 tggtgaaacc tgaaaagctc aaggtaaacc tcaacattga atatgtagcg atggaaatcc
    11401 cgaacgactt tatcgtaggt tacggactgg attatgatgg tttcggacgt aattatcccg
    11461 atatttatac agtagtagat taatattaaa taggtaccag tttaaatggt aaatagtaaa
    11521 tcgttaaatt gtaaataaca aaatgttgaa catcgtaatt ttcggtgctc cgggttcagg
    11581 aaaaggaaca cagagcgaac gtatcgtaga aaagtatgga atcaatcaca tctcgacagg
    11641 agatgtattg cgtgctgaaa tcaagaatgg cacagaactg ggtaaaacag ctaaaggtta
    11701 tatcgaccaa ggtcaattga ttcctgatga attaatgatt gatattctgg caagcgtatt
    11761 cgacagcttc aaagatagca aaggggtaat tttcgacggt ttcccaagaa caattgcaca
    11821 agcagaagca ttaaagaaaa tgttggcaga aagaggacag gacgtttctg taatggttga
    11881 cttggatgtt ccggaagaag aactgatggt acgtctcatt aaacgtggca aggattccgg
    11941 tcgtgctgat gataacgaag aaacaatcaa gaaacgtctg catgtatatc attcacagac
    12001 tgctccactg atcgactggt acaagaacga aaagaaatac caacacatca acggcttggg
    12061 tactatggaa ggtatcttcg ctgaaatctg cgaagcagta gataaattgt aataatacaa
    12121 tattataaat aaataagtca gtagccggag tgttctaatt aactgctcta actactgact
    12181 actttaactc tttaaaaaaa tatggctgag tcgaattttg ttgattacgt aaagatatac
    12241 tgtcgctcgg gtaagggcgg aagaggctct acgcacatga ggcgcgagaa atattgtcct
    12301 aacggaggtc ccgacggggg cgatggtgga agaggaggtc atatcatctt gcgcggtaac
    12361 cgtaattact ggacattgct gcacttgaag tatgaccgtc atgcaatggc cggtcatggt
    12421 gaatcgggga gcaaaggacg tagtttcgga aaagacggtg cggataaaat aatagaagta
    12481 ccctgcggaa cggtagttta taatgccgag acaggggagt atctttgtga cgtaacagaa
    12541 gacggacagg aagtggtctt gctcaaaggc ggtcgcggcg gtcagggtaa ctggcatttc
    12601 aagacggcca cccgtcaggc tccgcgtttt gcgcagccgg gagagccgat gcaggaaatg
    12661 accgttatca tggagctgaa actgcttgcc gatgtcggtc tggtaggttt cccgaatgcg
    12721 ggaaagtcaa ctttgctttc ttccatttcg gctgccaaac cgaaaattgc cgattacccg
    12781 tttactacgc tcgaacccaa cttgggcatc gtttcctatc acggtggaaa atcctttgtg
    12841 atggcggaca taccgggtat tatcgaaggt gccagccagg ggaaaggttt gggactgcgt
    12901 ttcttgcgtc atatcgagcg taattcatta ctgctgttta tggttccggc agacagcgac
    12961 gacattcgta aagaatacga agtcttgctg aacgaactgc gtaccttcaa tcctgaaatg
    13021 ttggacaagc aacgtgtgtt ggctgtcacc aagagtgata tgctcgatca ggagttgatg
    13081 gacgagattg aacctacatt gccggaaggc attccacatg tattcatatc ttctgtttcc
    13141 ggtttgggca tctcggtgtt gaaagacatc ctttgggaag aactgaacaa ggaaagcaat
    13201 aagatagagg acatcgttca ccgtccgaaa gacgtgaccc gtctgcaaca ggaactcaaa
    13261 gacatgggcg aagatgaaga catcgtttat gaatatgagg aagatgtcga cgatgacgat
    13321 gatatcgatt atgaatacga agaagaagat tgggaagaaa aatgatttca cttacaaaac
    13381 ataacgagtt gaagggatat aagtcactgg aggcatatcc cgaagtagct cattttgtaa
    13441 ctacgcgtca cgaaggtata agcaccggag cttacggctc tttcaactgt tcgccttata
    13501 ccaacgactc atgtatgaat gtcaatcgca atcagagctg gttgtttcag tgcatgaatc
    13561 atcagataaa ggaattattt attcctgaac agaatcatgg ctgtgccagt ctgattatca
    13621 atgaatcatt ttttaaagaa tcattggaaa tgagacggct acttctgcga ggaatggatg
    13681 ccttgataac taatgtgccg ggatattgcg tttgtgtcac gacggcggat tgtgttcctg
    13741 tattgctgta cgacaaaaaa caacacgttg tggctgccgt tcatgccgga tggaaaggaa
    13801 cagtgaagca tattgtcagt aatgtgatgg accacttgaa taagatgttc gggacgcaag
    13861 gcgaagatgt gatagcttgc atcgggccga gcatttcgct cgaatcattt gaagtaggtg
    13921 atgaggtgta tgatgctttt gaagaaagcg gcttcgatat gtctcttatt tctatgaaga
    13981 agaaggagac gggcaaatat catattgatt tgtgggaagc caaccggatt gaattactga
    14041 atctcggagt gcctgcagaa cagatagaag tggccggaat ctgtacctat attcatcatg
    14101 atgaattctt ctctgcacgt agactgggaa tagattccgg tcgtacattg tcgggaataa
    14161 tgattagaaa gtaataatta gcgtccgtaa tcgcaggacg ctgatgattg gtttatgata
    14221 agttatgttt gaaataaaag tatctaaaga aataaaagac gcatgcccgg tttttgccgg
    14281 agccgccgtg tatgctgcgg tgaagaatac tgcttacaac gaagggcttt ggcaggaaat
    14341 cgacgctttt actaggcaac tgacttccac aacacagatg gaagacatca aacatcaacc
    14401 cgttatcttt gctacccgtg aggcttataa acgttgtggc aaagaccccg gacgttaccg
    14461 cccgtcagcc gaagctctac gccgccgcct gatgcgtgga attcctttat atcagattga
    14521 tacgttggta gaccttatta atttagtgtc tcttcgcaca ggacattcga tcggtggttt
    14581 tgacgcggac aaaatacaag gtacgcatct tgaactcggt atcggcaaag caggagaacc
    14641 gtttgaaggt atcggacgcg gtgtattgaa tatcgaagga ttacctgtat atcgtgattc
    14701 tttcggcgga atcggaaccc cgacaagcga ccatgaacgt acgaagatgg acctcgaaac
    14761 tactcatatc ctagccatag tcaacggtta taacggaaaa gaaggtttgc gagaagctgc
    14821 tgaaatgata cagaccttat taagaaacta tacagaatcg gatggaggcg aaatcgtatt
    14881 cttcgaataa tt
//
