LOCUS       c00058_gnlPro..        16561 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BAADKHLK_58.
ACCESSION   c00058_gnlPro..
VERSION     c00058_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:59:17
            Original ID  :: gnl|Prokka|BAADKHLK_58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 8757
            Orig. end    :: 25318
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16561
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[18757:21284]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12527
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16561
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16561
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             90..347
                     /locus_tag="ctg58_13"
                     /transl_table=11
                     /translation="LKDVSSVSGSIDGEVECHPVECLARETEDGIRDRETAVVYIVLIV
                     GWVQPFIVVVVDVGTGLYQHIRFENEIPLLGSDCKTFFAV"
     CDS             313..471
                     /locus_tag="ctg58_14"
                     /transl_table=11
                     /translation="LVAIVKPSLPFSDTTPFSVSSSYWAMTANGKSNNAAIMIISCFIL
                     VCLMDKL"
     CDS             complement(466..1521)
                     /locus_tag="ctg58_15"
                     /transl_table=11
                     /translation="MLVYISRRNGAFFRDYGRVLHDQAIYGVKPEGKLSVTYDKQTFSF
                     PDGETYELCKPNYTITEWYKDSIAPEDLFCTVRIPLRHVGMGQMMAIDRREIEALAAKS
                     NYPEYGISGRCNYITEKGVTGVGLSGNKAQHLDLTVELGFSSDMGVTNSRYPEDICEGQ
                     AQINQGSMMGLSYDQLDISTADMEDVDLYMQSLGVPARRNINDPQVILGEQKFYEAKCH
                     LCHVTTLHTQAGGSTLLNGTRLPWLGGQTIHPYSDFLLHDMGSEIMGVGLNDNYVSGLA
                     RGNEWRTTPLWGIGLQEKVNGHTYFLHDGRARNLTEAIMWHGGEGEASKNLFKQMSKEE
                     REAVIAFLNSL"
     CDS             1591..1752
                     /locus_tag="ctg58_16"
                     /transl_table=11
                     /translation="MATAAGIAGINRSETASVAIVAGAYIVVETVAVVETDRVGSCYPV
                     GVRIVGDR"
     CDS             1749..1955
                     /locus_tag="ctg58_17"
                     /transl_table=11
                     /translation="MSLGKSLKSLLTAHIRSGHLFYPYPFYRPLHKLRMQRAGVARMLT
                     GKIASYHFIGFLNLFPNNASRIV"
     CDS             complement(2046..3311)
                     /locus_tag="ctg58_18"
                     /transl_table=11
                     /translation="MKKKNYFYLAALSLAMTFSMGACSDNDDPTPDGGGKDPVSLDYSS
                     ENASAWGNYMYNVAMLLNNDATTLYNSWVTDYVDEQGSHGPYATIFKDQTAGAYQSPLS
                     CIEEMIESGMWNIANEVGDAKIKDPYTKYTSGDKEGGLYAVESWYSWHSRDDYTNNIFS
                     IRNTYYGRIDDNDVSKVDGNLSAFNSYKDFDDEGDIAEHSLSKLIASTNPDLDEEIKTL
                     IFASAKAIQAIPQPFRNNIDSEESVAAMNTCMELANLLLNEAKPYVNQTFGDPEYDDDL
                     DAIAEQFVDAVVLPTYKDLQEKNKLLLDAVNQFRQNPSNDNFEKACNLWITAREPWEKS
                     EAFLIGPVANLGLDPNMDSWPLDQNGIVQVLNSQNWDDLEWSGNFDEEDEAIGAAQSVR
                     GYHTLEYLLFKDGQPRTVDGAK"
     CDS             3525..3923
                     /locus_tag="ctg58_19"
                     /transl_table=11
                     /translation="VLAFAFFLWVVVFVADERIDYGYAHIVFTNRTQVEPHFATIADRT
                     FGDRGCLCIRRTAALVVVDTAEVVGFAQVAVYHVCACGDIFVFVLQVSRIDAQRYVSIF
                     DVCFRFVGIGSRIVAIVEGTAYFQSRYS"
     CDS             3981..4385
                     /locus_tag="ctg58_20"
                     /transl_table=11
                     /translation="LLTTGNPCVAVETVGVQSGNDQSLVVETCVASAERTEHFDTVFVP
                     GRRKDGRFAFRTRSSEEVDRLMMLVGQTDRDDQMTGTDIEGRMDKTCDVELFQSNFTAF
                     FNFHFVFSVFCVFYLIGTTRTSSLKFYFCS"
     CDS             4392..4655
                     /locus_tag="ctg58_21"
                     /transl_table=11
                     /translation="LGIEFVIESQDKTGYGDRIAMVFLASVVRTPETVDAVVHKVCEDL
                     PISAEAELVISVGINVCGLFHCGFFCCCFFLSLCKSRYTRGE"
     CDS             complement(5139..5270)
                     /locus_tag="ctg58_22"
                     /transl_table=11
                     /translation="MTQLAYVLVVPYLCNDRFLGMKRLCQAYVTGVSYSGNSCAKPM"
     CDS             5361..5723
                     /locus_tag="ctg58_23"
                     /transl_table=11
                     /translation="LFVRRERAFAFSHAVVSPASEPSHQLANGFLHQFVGHPVQHPDET
                     ERIGQFIGRAEISTSVGLLLLVFRADDVPQFDFVADLLFCDSPQASSGFGAILFHAEQI
                     GGGDVGRVDFFFHIFH"
     CDS             6391..9120
                     /locus_tag="ctg58_24"
                     /transl_table=11
                     /translation="MNKRFSTLLAAALVAGSFSSAFAQLEGRNVEWKDAQASRAYYLAG
                     VHFVSPTDYLQAFSLQGLVNGADITAANPVAAAQWTVETKKVGTVTHYAFKNIEGEQYL
                     AFEKKDGAYALAAKKEANDETKSFRWFTVAANGNLQAVLSDEKEPYFLGLKNDGTADWS
                     LALLQSSEHHTDGSTSVIKKKVALYEIYNDQITAEAFASKFGENFTIEFPETLDDMDVF
                     ENVSVEKIANDNLGFKLVDNKGTKDTKDDEYVVLANERVSNSELAANAIGYRYAKMTAK
                     AIKDKKIDDKNTVFYAEENETNIGDGKYALVQKVKVGDLDNKDVTFGKVTNDETTRQLA
                     SVEYDCHSTFMGVTVGKGTRVANTEVANERMLIVNVTAKVADKKNSSALGLKNDFTGAR
                     WYDKVSEADFDQPQGQWLVAAGSAANTIKLINVQKPGFVQDNIRLYEAEGENTYTVFAS
                     DLGLSGLETITLTKVEDYDKLNGYYSTLSDINQKFAFVTTGEYANEEAGSDLYLKAGVE
                     GDVVTVVPHAGSEWELIRNEKAQAVTANYKYYDGEKWVELNGKGNEEKGILPADTVRLA
                     YSYAINADELGLGTAWKMAKDDIEFFLKENGKGTYAIVYGATADEVKEYGVINGSEELV
                     AETTDFTNSTPFEIIDLDAAPSLAADSKHMTFEATNSIGFIASDENNNAVLAKETAALW
                     VDSVNAEGYATPKFFISYAGKMMTTAKKFKEIVDKAYANDEISKKEYAELTADENLYYK
                     SVERIKFVDAERLSGEDTLVIADEKYTGKDIEDFKFKVTENEDGDYVLKANGNYVYVIN
                     GNLVYGTDAKEAEAFVIEVTSAPTANEGIATSEVKVIAGEGNVTIAGAAGKKVVISNIL
                     GQVVANTVVSSDNATIAAPAGVVVVAVEGEAAVKAIVK"
     CDS             complement(9316..9582)
                     /locus_tag="ctg58_25"
                     /transl_table=11
                     /translation="LNCAQFSFSNFISLSCLFRFRHAKIRLFPLSEKDCKGRGMLNRRK
                     YLQIGIRGIKTKPRQYEYRRGLFFVCHPVFTEGKAVELLISLL"
     CDS             complement(9707..9967)
                     /locus_tag="ctg58_26"
                     /transl_table=11
                     /translation="VRLSVFGEDFFCHRIQMIAIGFQTVFDHADTAFREDTALQRGVCL
                     QADDYFVFLIDVTGSVCVNPLGKLRFGIIYSFLPFNLKHLG"
     CDS             10001..11788
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_27"
                     /sec_met_domain="Gly_radical (E-value: 1.6e-45, bitscore:
                     145.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 7.4e-221, bitscore:
                     725.6, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAARRSAIITGLPDAYGRGRIIGDYRRVPLYGTQILIEEKKRFQ
                     KRLDIQELTEEIIQSREEITEQIKALKAFERMCAGYGFDVTRPAKDAREAVQFLYLAYL
                     AAVKDQDGAAMSLGRTSTFLDIYIEKDICEGKLTEEEAQELIDQFIIKLRIVRFLRTPE
                     YNDLFSGDPVWVTESLGGQGVDGRSLVTKTSYRYLHTLYNLGPAPEPNLTVLWFNNAPD
                     NWKNFCAKVSIDTSAIQYENDDLMRPDYGDDYGIACCVSPMKIGKQMQYFGARANLAKC
                     LLYAINGGRDEKSGVQVAPRFEPITSEYLDYNEVMEKYEQMMRWLAKVYVNALKIIHYM
                     HDKYAYEAFEMGLHDGDVERIRATGIAGLSIVADSLAAIRDTKVKVIRDERGLAVDFER
                     EGEYVPFGNNDDRTDSIAVDITEKFMEYLRQHQTYRKATPTQSILTITSNVVYGKKTGT
                     TPDGRPGGTPFAPGANPMNGRDTKGAVAALASVAKLPFQHAHDGISYTFAVSPATLGKE
                     RDIQVNNLVSLLDGYFTPDGGQHLNVNVFDKDLLLDAMEHPEKYPQLTIRVSGYAVNFV
                     KLTREQQLDVISRTINNSL"
     CDS             11796..12527
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 73; E-value:
                     9.7e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_28"
                     /sec_met_domain="Radical_SAM (E-value: 1.2e-35, bitscore:
                     114.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LINMLGRIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWE
                     VKRETPYLLEPEALLAEVLRYKNFIAKGGVTVTGGEPLLQPEFLKEFFRLCRENGIHTA
                     LDTSGYICSGKALEVLEQVDLVLLDIKTIDAGLHPRLTAVKLDNTLRFLDELEKRGIPV
                     WIRHVIVPGLTDDDEALSKLAEYISSYNVVQKAELLPYHTMGAYKYEAQGLDYKLKGVE
                     PLSAERLANAKAIFMKHGITV"
     CDS             13112..13678
                     /locus_tag="ctg58_29"
                     /transl_table=11
                     /translation="MEPIINSQVPEFKVQAFQNGSFKTVSSEDIKGKWAIFFFYPADFT
                     FVCPTELVDMADKYGKFQEMGVEVYSVSTDSHFVHKAWHDASETIRKIKYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKIAEIHDNGIGRNADELLRKVEAAQFVASHP
                     NEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             13665..15248
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg58_30"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.2e-48, bitscore:
                     156.0, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVRSKVMLDSAMKDQLSGIFSGLVSQYVFDIQVAPDHESRQELID
                     LLGDVASCSDHLSCSVADGEGLQFTIVKDGMPTGIRFRAVPNGHEFTSLLLAVLNSDGK
                     GKNIPDESICARIRALNGPIKLTTYVSLTCTNCPDVVQALNVMATLNSRITHETVDGAI
                     NQKEVEAMKVQGVPSVFADGRLINVGRSDLGELLSKLEAQYGINEGGVDNSVEKPVKNY
                     DVLIVGGGPAGAASAIYSARKGLNVAVIAERIGGQVKETVGIENLISVPQTTGQQLAND
                     LLTHINDYPVDILEHRRVDKVELDGSAKFLTTSTGERFSAPALIVATGASWRKLNVPGE
                     ADYIGKGVAFCPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKAD
                     QVLQEKAKSLPNVEVFLHSQSLEVLGNGDKVTGLRVKDRKTDAERVIDLDGIFVQIGLA
                     ANSGVFRDVVETNKPGEIVIDAHCRTNVPGIYAAGDVSTVPYKQIIIAMGEGAKAALSA
                     FEDRMRGSIG"
     CDS             15264..15392
                     /locus_tag="ctg58_31"
                     /transl_table=11
                     /translation="MNDEGVQIELHECVFKIAHLFFFTHKAPTFTTGQPHQNFPRL"
     CDS             complement(15966..16172)
                     /locus_tag="ctg58_32"
                     /transl_table=11
                     /translation="LQGNCTKIQKSYKIYQRKKQGLIIQVFPISSVTVSLISFLSIDIQ
                     SVSLVIYARFLYHYGITTLSLAI"
ORIGIN
        1 gtagtcaggt aagcgtgtga gaatggagtc ttgaacttgc cgacacgtat ggcaaaactc
       61 ttttttatct ctacgtcgaa ccaagcctgt tgaaggatgt ttcctccgtt tccggcagca
      121 ttgatggaga ggttgaatgt cacccggtcg aatgccttgc ccgtgaaacc gaggatggca
      181 taagggatcg agaaaccgct gttgtgtata ttgtcctgat tgtaggctgg gtccagccct
      241 tcatcgtcgt agtagttgat gttggcactg gtctgtacca acatataagg tttgaaaacg
      301 aaatccccct tcttggtagc gattgtaaaa ccttctttgc cgtttagcga tacgacaccg
      361 ttttccgtat cttcctcata ttgggccatg acggccaacg gcaagagtaa taatgctgca
      421 attatgatta tcagttgttt cattttagtt tgtcttatgg ataaattata aggagttgag
      481 gaatgcgatc actgcctcac gctcttcctt gctcatttgt ttgaataaat ttttggaggc
      541 ttccccttcg cctccatgcc acatgatggc ttcggtcagg ttgcgggcgc gtccgtcatg
      601 aaggaaatag gtatgaccgt tgactttctc ctgcagcccg ataccccaaa gcggcgtagt
      661 acgccattcg tttcctcgtg ccaggccgct gacataattg tcgttcaacc cgactcccat
      721 gatctccgac cccatgtcat gcagtaggaa atcagaataa ggatgtatgg tctgtccgcc
      781 gagccatggc aaacgtgtgc cgttgagcag tgtggaaccg cccgcttgcg tgtgcagcgt
      841 agtgacgtgg cagagatggc atttcgcttc gtaaaacttt tgttctccta agatgacctg
      901 agggtcgttt atgttgcgcc gtgccggtac accgaggctt tgcatgtaaa ggtccacatc
      961 ttccatatcg gcggtcgata tgtcgagctg gtcatacgag agccccatca tgctgccttg
     1021 gttgatctga gcctgccctt cgcaaatatc ttccggatag cggctgtttg tcacgcccat
     1081 atcgcttgaa aagcccagtt cgacggtcag gtcgagatgc tgtgccttgt ttcctgaaag
     1141 gccgacaccg gtgacaccct tctcggtgat atagttgcaa cgtccgctga tgccatattc
     1201 cggataattg cttttggcag cgagcgcttc gatttccctg cggtcgattg ccatcatctg
     1261 tcccataccg acgtggcgta acgggatgcg tacggtgcag aacaaatctt ccggggcgat
     1321 actgtcttta taccattcgg ttatcgtgta attgggtttg catagttcgt aagtctctcc
     1381 gtcggggaag gaaaaagtct gcttgtcgta tgtgacggac aacttacctt ccggtttgac
     1441 gccgtagatg gcttggtcgt gcaatacacg tccgtagtcg cggaagaaag caccgttgcg
     1501 gcgggagata tagaccagca tggaagagaa accgtagttg cccgatccgc cgttttccca
     1561 caatgtcggt ttggtccttc ctgcgttgcg atggcaactg ccgcaggaat agccggcata
     1621 aacaggtccg agaccgcctc cgtcgccatt gttgctggtg cgtacatcgt cgtagagacc
     1681 gtcgccgttg ttgaaacgga tcgagttggc tcctgttatc cagtcggcgt tcgtatcgta
     1741 ggcgaccgat gagtttagga aaatcgttga agtccctgct gacagcgcat atccgttcgg
     1801 gacatctatt ttatccatat ccattttatc gtcctcttca caagctgcgc atgcaaagag
     1861 caggagtagc gaggatgtta acaggtaaga ttgcttcata tcattttatt ggttttctga
     1921 atttatttcc gaataacgcg agtcgcattg tgtaataact ctgaaaccct gaaacagcgg
     1981 gcatttgtct gctgtttcaa ggtttgtcat gatctattat caagttttat gtctcagagg
     2041 catgtttatt ttgctccatc gacagtgcgg ggctgcccgt ctttgaacag gagatattcc
     2101 aatgtatggt aaccacgtac gctctgtgcg gctccgatgg cctcatcttc ttcgtcaaag
     2161 tttccgctcc attccaggtc atcccagttt tgtgaattca atacctgtac gataccgttc
     2221 tggtccaaag gccagctgtc catgttgggg tccagaccta agttggcaac cgggccgata
     2281 aggaaagctt cgctcttttc ccacggttcg cgtgccgtga tccataagtt gcaggccttt
     2341 tcgaagttgt cgttgcttgg gttctgtctg aactgattca ctgcatccag caaaagcttg
     2401 ttcttttcct gcaagtcttt ataagtagga agaacgaccg catcgacaaa ctgttcggct
     2461 attgcatcaa ggtcatcgtc gtattcagga tcgccgaatg tttggtttac atacggtttt
     2521 gcttcattta acaacaggtt ggccagttcc atgcaagtgt tcattgcggc aacggactct
     2581 tcgctgtcga tgttgttgcg gaacggttgc ggaatagcct gaatcgcctt tgcagaagcg
     2641 aaaatcagcg ttttgatttc ttcgtcgaga tccgggttgg ttgaagcgat cagttttgaa
     2701 agcgagtgtt ctgcgatgtc tccttcatcg tcgaaatctt tgtaagagtt gaatgcactc
     2761 aggtttccgt ccactttgga cacgtcgttg tcgtcgatgc ggccgtagta tgtgttacgg
     2821 atggagaaga tattgttcgt atagtcgtcg cgcgaatgcc agctatacca tgattcgacg
     2881 gcataaagac cgccttcctt gtcaccgctg gtatatttgg tatacgggtc cttgatcttg
     2941 gcgtcaccta cttcgttggc gatgttccac ataccgcttt cgatcatttc ctcgatacac
     3001 gagagcgggc tttggtaagc tccggcagtc tggtctttga agatcgtggc gtatggaccg
     3061 tgtgaaccct gctcatcgac gtagtcggtc acccaggagt tgtagagcgt ggtcgcatcg
     3121 ttgttcagca acattgccac gttgtacata tagttacccc atgcactggc gttttcagaa
     3181 ctgtagtcca ggctgacagg atcttttccg ccaccatcag gcgtgggatc gtcgttgtcg
     3241 ctacatgctc ccatcgagaa tgtcatggcg agcgataagg ctgccagata gaaataattt
     3301 ttctttttca ttttattgat taagctatta aattgtttat gttgttttta tttgctgagg
     3361 aaccagccga tgtaggcgat agccaggctg aattcgtttt cgctgttata tttgccgcct
     3421 ccgattttgc gtgttgtata gtctgctttc acgacaagat taggtaaagc ataccaattg
     3481 gctccggctg tccacatgct tactttgttg cgtaaatcca tcgtgtgctt gccttcgcct
     3541 ttttcctgtg ggttgtagta ttcgtagcgg acgaacggat agattacggg tacgctcata
     3601 ttgtctttac aaaccgcacg caggttgaac cccacttcgc caccatagct gaccgcacgt
     3661 ttggcgatcg gggttgtctg tgtataagga gaaccgccgc tttggtggtt gttgacactg
     3721 ctgaggtcgt cggctttgct caggttgccg tatatcatgt ttgcgcgtgc ggtgacatat
     3781 ttgtttttgt attgcaggtc agccgtatag atgcgcaaag gtatgtttcc atatttgacg
     3841 tatgtttccg gtttgtcgga attggctccc gtattgtggc aatagtagaa ggaaccgcct
     3901 attttcaatc ccggtactcc taaatagttc aggcgggcca catagcccgg tgaggtgaag
     3961 ttatctgttt cgaatagtcc ttgcttacca ccggcaaccc atgtgttgcg gtcgaaaccg
     4021 ttggcgttca atccggcaac gaccaaagcc tggtagttga aacgtgtgta gcctcggccg
     4081 aacgtaccga acacttcgat accgttttcg tgccaggtag aaggaaggat ggtcgtttcg
     4141 ccttccggac gagaagttcc gaagaagttg atcggctcat gatgctcgtt ggtcaaaccg
     4201 accgggacga tcaaatgacc ggcacggaca ttgaaggccg gatggataag acgtgtgatg
     4261 tggaattgtt ccaaagcaac ttcaccgcct ttttcaactt ccatttcgta ttctccgttt
     4321 tctgtgtttt ctatctcata ggcactaccc gtacctccag cctcaaattc tatttctgct
     4381 cctaataccc attgggaatt gaatttgtaa tcgaaagcca agacaaaacg gggtatggag
     4441 atcgaattgc gatggtcttt cttgcttccg ttgtccgtac cccggaaacg gttgatgccg
     4501 tagtccataa agtttgcgag gatctcccca tatccgccga agcggaactt gttatatccg
     4561 tcggcataaa tgtctgcgga ttgttccact gcggattttt ctgttgttgt ttcttcttgt
     4621 ccctgtgcaa aagccgttat acaagaggtg aatagagtga ttgctaataa attagttaac
     4681 cttttcattg cgttttttaa tttttggcaa aattagaggg gctgtcaacg gtgtgcaatc
     4741 gcaattagta ggtaaaaagg ttccgatgtt acccatttgt aggtattgcg cctgaatatc
     4801 accttgatta ggtagtaaaa gacgtttttt tactcacata taggtattgt aggaggtggg
     4861 aagtgcccgt atctttgcaa tgtcattaag aaagtaacac tattagtata atcgctatat
     4921 caaaaccttt tgtcaattat gtaagcatat aagatgatta actatatcga aaagttttta
     4981 ttggttattt tcggtataaa aaagaagcct ctctgtgaag agaggcttct tttttatgtt
     5041 tccgtttccc attcgcttct gtccggaatc tgttcggcgt cgagtcttgg acttgttccc
     5101 gcaaaggtct gtttgctgct ccggctgtgc caaaacaatt acatcggctt ggcacaactg
     5161 tttcctgagt aggaaacgcc tgttacataa gcttggcaca accgtttcat gccgaggaaa
     5221 cggtcgttac ataggtatgg tacaaccaat acgtaggcaa gttgcgtcat gtgaacttac
     5281 cagtcgtatg cctcgaagta ggcatcgaac tttccgggat cgttgatacc gcactgtttc
     5341 agtatgttca acatgctttt ttgttcgtcc ggcgagagcg ggcgttcgcc ttttcgcacg
     5401 cggtagtaag tcctgcgtcc gaaccgtctc atcagcttgc aaatggcttc ctgcatcagt
     5461 ttgtagggca tccggtccag catcccgatg aaaccgagcg cataggtcag tttatcggca
     5521 gggcggaaat aagcacatcg gtcggtttgc ttctcttggt atttagggct gatgacgtgc
     5581 cacagtttga cttcgtcgcc gatctgttgt tctgcgattc tcctcaagca agtagtggct
     5641 ttggggcaat cttgtttcat gcagagcaga taggaggcgg ggatgtcgga agagtcgatt
     5701 ttttctttca tatattccat taatgtatta tagttgtttg atccgtctgt gacggacgtt
     5761 gatgtaaaga tacataataa tgtaaggttt tgcaagtctt gaagctgtta ttgagctaag
     5821 caaccaatac tccgtatttt gtatatcttt aacagaaggg gaagcttttc caagatgaaa
     5881 ttacgaaacc tgctgttttt gccgtttttc ccctccaatg tgaataaagg aagtttatct
     5941 tataggtgat tgattatctt tgttttgatg aagatgtaaa gatgtttggc gagcggttga
     6001 aaacagctct ttttttatat ggccttaggc actttttgca atgtaagtca ttgctaataa
     6061 gaagtatatg ggtataagaa gaaaaatagc gaaaaaacgt acgttttctt tcgccatttt
     6121 cactgcacaa aaatacaact actttttgaa cctgcaatcc tttcttccaa ttatttttcc
     6181 ttttctatat tctttcttat caatcagata gcttaacaag tacgaaaaac cagctttcca
     6241 acacaaaccc tcccgaaagc ccctcaaaaa tgactaaaaa aaacgtacgt tttctctcgt
     6301 caaaatacag gaatttggta aaaacctgtt aaacaggaag taagaacgat attcaatata
     6361 catattatta ttaattaaac attttagatt atgaacaaga gattttctac tcttttggct
     6421 gccgctttgg tagccggttc ttttagttca gctttcgcac agttggaggg gcgtaatgtt
     6481 gaatggaagg atgcacaagc aagccgcgct tattatttgg caggggtgca ttttgtgagt
     6541 ccgacagatt acttgcaggc tttttctttg caaggattag tgaatggtgc tgatattacg
     6601 gctgcaaatc ctgttgctgc tgcacaatgg actgttgaaa ctaaaaaggt tggaactgtt
     6661 acacattatg ctttcaaaaa tattgaagga gaacagtatc tggcttttga aaagaaagat
     6721 ggagcttatg ctttagctgc caaaaaagag gcaaacgatg aaacaaagtc gtttcgttgg
     6781 tttactgttg cagcaaacgg caatttgcaa gctgtgcttt ctgatgaaaa agaaccgtat
     6841 tttttaggac tgaagaacga tggcacagca gattggtcat tggctttatt acaaagttct
     6901 gagcatcata cggatggatc tacttccgtt atcaagaaga aggtagctct ctacgaaatc
     6961 tacaacgacc aaattacagc agaagctttt gcgagcaagt ttggcgaaaa cttcacaatc
     7021 gagttcccgg aaacattgga tgacatggat gtgtttgaaa atgtaagcgt agaaaaaatc
     7081 gccaatgata atttgggttt caagttggtt gacaacaaag gcacaaaaga tacaaaagac
     7141 gatgaatatg tagttttagc aaacgaacgt gtttccaact cagagttggc tgccaacgca
     7201 atcggttatc gctatgcaaa aatgactgct aaagcgatta aagacaagaa aattgacgac
     7261 aagaacactg tattctatgc tgaagagaac gaaacaaaca tcggagatgg taaatatgca
     7321 ttagttcaga aagtaaaagt tggtgacctg gacaacaaag atgtgacttt cggtaaagtg
     7381 acaaatgatg aaacaactcg tcagttggct tctgtcgaat atgactgcca ttctactttc
     7441 atgggggtta cagtaggcaa gggtacacgt gtcgctaata ctgaagttgc caacgaaaga
     7501 atgttgatcg taaatgtaac tgccaaagtt gcagacaaga agaattcttc tgcactgggg
     7561 ttgaagaatg atttcactgg cgcacgttgg tatgataaag tttctgaagc tgacttcgat
     7621 cagccacagg ggcagtggtt ggttgctgcg ggttcagctg ctaacacaat taagttgatc
     7681 aatgttcaga aaccgggttt tgtacaagac aatatccgtc tatatgaagc agaaggtgaa
     7741 aatacttaca cagtatttgc ttctgattta ggtttgtctg gtcttgaaac aatcactttg
     7801 acgaaagttg aagattatga caagctgaac ggctactaca gtacattgtc tgacatcaat
     7861 cagaagttcg cctttgtaac aacaggtgaa tatgctaacg aagaagccgg ttcagatctg
     7921 tatttgaaag ctggtgtaga aggagatgtt gtaactgttg ttcctcatgc tggttctgaa
     7981 tgggaattga tccgtaacga aaaagcacag gctgttactg ccaactacaa atattatgac
     8041 ggtgaaaaat gggttgaact gaatggcaaa ggtaatgaag aaaaaggtat cctgccggct
     8101 gatacagttc gtctggctta ttcatatgca atcaatgctg atgaattagg tttgggaaca
     8161 gcttggaaga tggctaagga tgacatcgag ttcttcttga aagaaaatgg taaaggtaca
     8221 tacgctatcg tatatggcgc tactgctgat gaagtaaaag aatacggtgt aatcaatggt
     8281 tctgaggaat tagtagcaga aacaactgac tttactaact ctactccgtt cgaaatcata
     8341 gacttggatg ctgctccttc tttggctgct gacagcaagc acatgacatt cgaagctact
     8401 aatagcattg gcttcatcgc ttctgacgaa aataacaacg cagtattggc taaagaaaca
     8461 gctgctttgt gggttgactc tgtaaatgct gaaggttatg caactccgaa gttcttcatt
     8521 tcttacgctg gcaagatgat gacaactgct aagaagttta aagaaattgt tgataaggct
     8581 tatgctaatg atgaaatcag caagaaagaa tatgcagaac ttactgctga tgaaaatctt
     8641 tactacaaga gtgtagaacg tatcaaattt gtagacgctg aacgtctgtc tggtgaagac
     8701 actttggtta tcgccgatga aaagtatact ggcaaggata tcgaagactt caagttcaaa
     8761 gttactgaaa acgaagacgg tgactatgta ctgaaagcta atggtaacta tgtatatgta
     8821 atcaacggta acttggttta cggtacagat gctaaggaag ctgaagcatt tgtaatcgaa
     8881 gtaacttctg ctcctacagc caacgaaggc atcgcaacat ctgaagtgaa agtgatcgct
     8941 ggcgaaggta acgtaacaat cgcaggcgct gccggtaaga aagttgttat cagcaacatc
     9001 ttaggtcagg tagtagctaa cactgtcgtt tcttctgaca acgcaactat cgctgctccg
     9061 gcaggcgtag tagttgtagc tgttgaaggc gaagctgctg taaaagctat cgttaagtaa
     9121 cgattgatac taaaaaaaca atactgtcta tcgtaagggt ggttagtgaa ccacccttac
     9181 acaggcacaa tgacatttta taatcaaata attctagaca acctgcgtga aaccgtatgt
     9241 aagaggtttt cttgatctat ggtttcaatt accctgcgac aggcgaacaa gcggttggat
     9301 ttaatattaa taatactaaa gtaatgaaat taaaagttct actgcttttc cctctgtgaa
     9361 gaccggatgg cagacaaaaa acaggccccg gcggtattcg tactgccggg gcttcgtttt
     9421 tattcccctt atccctattt gtaggtattt tctccggttt aacattcctc gtcctttaca
     9481 atccttttca gataggggga aaagacgtat ctttgcgtgc ctaaaccgaa atagacaaga
     9541 taagcttatg aagtttgaaa acgagaactg ggcgcagttc aaaggagaaa cctggaaaaa
     9601 ggagatcaat gtaagagact ttatccagaa caattacaaa ccttataacg gagacgatac
     9661 gttcctcgta ccctcttcgg agaaaacgaa gaaagtgtgg aacaaactaa ccgagatgtt
     9721 taaggttgaa agggagaaag gagtatatga tgccgaaacg aagcttcccc aggggattga
     9781 cacatacgga cccggttaca tcgataagga aaacgaagta atcgtcggct tgcagacaga
     9841 cgccccgttg aagcgcggta tcttcccgaa aggcggtatc cgcatggtcg aaaacagtct
     9901 ggaagcctat ggctatcatc tggatccgat gacaaaagaa atcttcacca aatacagaaa
     9961 gacgcacaac gaaggcgttt tttcagccta tacagacgag atgattgcgg cacgtcgttc
    10021 cgccatcatt accgggttgc ctgatgccta cggacgcgga cgtatcatcg gtgattaccg
    10081 tcgtgtacct ctgtacggaa cccagatcct gatcgaagaa aagaaacgtt tccagaaacg
    10141 tctcgatata caggaactga cagaagaaat cattcagagc cgcgaggaga taacggagca
    10201 gatcaaagcg ctgaaagcat ttgagagaat gtgtgccggt tatggtttcg atgtgacacg
    10261 tccggcaaag gatgcccgcg aagccgtgca gttcttgtat ctggcttacc tggcagccgt
    10321 aaaggatcag gatggagcag ccatgtctct cggacgtact tctactttcc tcgatatcta
    10381 tatcgaaaaa gatatttgcg aaggtaagct gacggaagaa gaggcacagg aattgatcga
    10441 ccagtttatt atcaaactgc gtattgtccg tttcctgcgt actccggaat acaacgacct
    10501 gttctccggc gaccctgttt gggtgactga atcgctgggc ggacaaggtg ttgacggccg
    10561 ttcgctggtg acaaagacat cttaccgtta tctgcatacc ttgtataacc tcggcccggc
    10621 acccgaaccc aacctgacgg tgctttggtt caacaatgct ccggataact ggaaaaactt
    10681 ctgcgcaaaa gtatcgatcg atacctctgc catccagtac gagaacgacg atctgatgcg
    10741 tccggactat ggcgacgatt acggtatcgc ctgctgtgtg tctccgatga aaatcggcaa
    10801 gcagatgcag tatttcggag ctcgtgccaa cctggcaaaa tgcttgttgt atgcgatcaa
    10861 tggcggacgt gacgagaaat cgggtgtgca ggtggctccc cgtttcgaac cgatcaccag
    10921 cgagtatctg gattacaacg aagtgatgga gaaatacgag cagatgatgc gctggttggc
    10981 aaaagtctat gtcaatgcac tgaagatcat tcactacatg cacgacaaat atgcgtatga
    11041 agcattcgag atggggcttc atgacggaga tgtggaacgt attcgcgcaa ccggtatcgc
    11101 cggcctttct atcgtcgccg actcgctggc tgccatccgt gatacgaaag tgaaagtgat
    11161 ccgtgacgaa cgtggtttgg ctgtcgactt cgaacgcgaa ggcgaatatg tacctttcgg
    11221 aaacaatgac gaccgcacgg acagtattgc tgtcgacatt accgagaagt ttatggaata
    11281 tctgcgccag catcagacat accgcaaggc aactccgaca caatctatcc tgacgatcac
    11341 atcaaacgtg gtctacggaa agaaaaccgg aacgactccc gacggccgtc cgggcggtac
    11401 gccgtttgct ccgggagcca acccgatgaa cggacgcgat acgaaagggg ctgtcgccgc
    11461 tttggcttct gtagccaaac tgccttttca gcatgcgcat gacggtattt cctatacatt
    11521 cgccgtttct cctgcaacgt tgggtaagga acgcgatatc caggtgaaca acttagtgag
    11581 cctcttagat ggttatttca cgcccgatgg cggccagcat ctgaatgtga acgtattcga
    11641 taaagacttg ctgttagatg cgatggaaca tccggagaaa tacccgcagc ttacgatccg
    11701 tgtttcgggc tatgccgtca acttcgttaa gctgacacgc gaacagcaac tcgacgttat
    11761 ctcgcgcacc atcaacaaca gtttataatt gtccattgat taatatgttg gggcgtatac
    11821 attctttaga gagtttcggg accgttgacg gtcccggaat tcgctttgtc gtttttatgc
    11881 agggatgtcc gcttcgttgt ctgtattgcc acaatccgga tacttgggag gtaaagcgtg
    11941 aaacgcctta tctgctggaa cctgaagcgt tgcttgccga agtgctgcgc tataagaatt
    12001 ttatcgctaa aggtggtgtt accgtgaccg gtggcgagcc tttgttacaa cctgaattcc
    12061 ttaaagagtt tttccgcctt tgccgtgaga acggtattca tacggcgttg gacacttccg
    12121 gctatatctg ttccggtaaa gcattggagg tgctcgaaca ggtcgatctg gttctgttag
    12181 atatcaagac gatcgacgcc ggtcttcatc cccgtttgac ggccgtaaaa ctcgataata
    12241 ctttacgctt tcttgatgaa ctggagaaac gcggcatccc tgtatggatt cgccacgtga
    12301 tcgtgcccgg cctgacggac gatgatgaag ccttgagcaa gctggccgaa tatatcagtt
    12361 catataacgt ggtccagaaa gccgaacttc tgccttatca tacaatggga gcttacaaat
    12421 atgaggcaca aggcctggac tataagctga aaggtgtgga accgctttca gcagagcgtc
    12481 tggccaatgc gaaagcgatc tttatgaaac acgggataac cgtataagcc taatcgagtg
    12541 tctgctcttt gatgatgatc ggtttacggc tgatccggtt gactgtgcgg acactgtcgc
    12601 tttcaatact ggtaacatct ccctcgcagt tggtgaaata gatgtaatgt cccatatcca
    12661 tgaaacgata gaccttacac ccttcgtgtt cgaacagata ttcgacttga taagtggaat
    12721 tgtttaccgg tttttccttt gtaaggggta tttgtgagac acatgaagaa agacatgcgt
    12781 tgcaaacgag caatagactt gctgaaaatg tattatacaa actagctctt ctcatcttcg
    12841 aatattttta agttaacatc caaagttaac aattaaagaa tcacatggta tgatcgaaag
    12901 gtattttacc tacaattagg tatattttta ttgttccgga aaacattact ttgcttccta
    12961 ttgtcatagt agataagtat gcttgcagat agaaatccgt ctatcggcag ataaaaatta
    13021 tcaatttgaa aaattctttc aatcagtatc ttacgattta cctttgtagg gtaaacaaaa
    13081 aatagtagta acaaattaaa tagtaaaaat catggaacca attatcaatt cacaagtacc
    13141 cgaattcaaa gttcaagctt ttcagaatgg tagtttcaag acagtaagta gcgaagatat
    13201 caagggcaaa tgggccatct ttttcttcta tcctgccgac tttacgttcg tatgtccgac
    13261 cgaattggtc gatatggctg acaagtacgg caaatttcag gagatgggtg tcgaagtata
    13321 ttccgtaagt acagactcgc actttgtaca caaagcatgg catgatgctt ccgaaacgat
    13381 ccgtaagatc aaatatccga tgctggcaga cccgacaggg gctttaagcc gtgcattcgg
    13441 tgtgatgatt gaagaagagg gtatggctta tcgcggtacg ttcctggtaa atcccgaggg
    13501 aaagatcaag attgccgaaa tccacgataa cggtatcggc cgtaatgcag acgaattgct
    13561 tcgtaaagtt gaagctgccc agttcgttgc ttctcacccg aacgaagttt gtcctgcaaa
    13621 gtggaaaaaa ggcgaagcaa ccttgaagcc gagtatcgac ttggttggta agatctaaag
    13681 ttatgttaga ctcagcaatg aaagaccagc tttcgggtat tttctccgga ctggtatccc
    13741 aatatgtatt tgatatacaa gtcgctcccg atcacgaaag ccgtcaggag ctaatagacc
    13801 tgcttggtga tgtggcatca tgctcggatc atttgtcatg cagcgttgcg gatggcgaag
    13861 gacttcagtt tacaattgta aaagacggta tgcctaccgg tatccggttt cgtgcagtac
    13921 ctaacggaca tgagtttaca tccttgttgt tagctgtcct gaatagtgat ggaaaaggta
    13981 aaaatatacc ggacgaaagt atctgtgccc gtatcagagc cttgaatggt ccgatcaagc
    14041 tgacgactta tgtttctctt acttgcacca attgtccgga tgtagtgcag gcactcaatg
    14101 tcatggctac tctcaatagc cggatcaccc acgaaacggt ggatggcgct atcaaccaaa
    14161 aagaagttga ggccatgaaa gtacagggag tcccttctgt ttttgcagat ggcaggctga
    14221 tcaatgtggg gcgtagtgat ttgggagaat tgctttccaa actcgaagcc caatacggaa
    14281 ttaatgaagg gggtgttgat aactctgttg aaaaacctgt taagaactat gatgtgttaa
    14341 tagtgggggg tggacctgcc ggtgcagctt ctgccatcta ctcggcacgt aaaggcttga
    14401 atgtcgcagt gatagccgaa cgtatcggag gacaggtcaa agaaacggtc ggtatcgaga
    14461 acctgatttc cgttcctcag actaccggac agcagttggc gaacgacctt ctgacacata
    14521 tcaacgacta tccggtcgat atactggagc atcgccgtgt ggataaagtc gaactggatg
    14581 gatcggcgaa atttctgacc acttctaccg gtgaacgttt ttctgctcct gcccttatcg
    14641 tggcgacagg tgcaagctgg cgcaagttga atgttccggg cgaagcggac tatatcggaa
    14701 aaggtgtcgc tttttgccct cactgcgatg gtccgttcta taaaggtaag cacgtagcgg
    14761 ttgtcggcgg tggaaattcg ggtatcgaag cggctataga tttggcaggc atttgttcga
    14821 aagtgacggt tctggaattt atggacgaac tgaaagccga ccaagtgttg caggaaaaag
    14881 caaagagctt gccgaatgtg gaagttttct tgcattccca atctttggaa gtgcttggta
    14941 atggcgataa ggtgacaggt cttcgtgtaa aagaccgtaa gacggatgcg gagcgggtga
    15001 tcgacctgga cggaatcttt gtccaaatcg gcttggcagc caatagtggc gttttccgcg
    15061 acgttgtcga aacgaacaaa ccgggtgaga ttgtaatcga tgcgcattgt cggacgaatg
    15121 ttcccggcat ctatgcggcg ggcgacgtct cgaccgtacc ctataaacag ataatcatag
    15181 caatgggaga aggggcaaaa gcggctctat ctgcttttga agaccgcatg agaggttcaa
    15241 tcggttaata tttagtattt gctatgaacg acgaaggtgt gcaaattgaa ctacacgaat
    15301 gtgtgttcaa aattgcacac cttttctttt ttacgcacaa agccccgact ttcacaacag
    15361 ggcaaccgca tcaaaatttt ccaaggttgt gatctccata cgaagtttct acaaatcctc
    15421 tatcactcta tcactacgaa ggttgtagct attaatattc aagcgttaga ggagtgatag
    15481 aggaaaacat cctgtatcac tgcctctatc actcctctaa caggacgttt ttatcatatg
    15541 attggaaacc aatatattgc cttcttttgc ctttgaaaaa gcatataaaa taatcgaata
    15601 aacaaatgta aaaacgaatg caataggtgt taaattgacg aaatacggtt cttcatttca
    15661 caaaagccct ctcttttttt agcagaaaca agcagataat tccgtaaaca cccccatgtt
    15721 gccatcctta acatccgggt gtagagagcc ggtacatccg ggtgtaaaag ggggcaacat
    15781 gggggtgtcc ggcaacaaaa gtaccgtgcc gaacaatgaa aaccacccgg ctttacctat
    15841 tttatagccg tttttacata aaataatcga gtgatttata gggatggaaa ttgggtgttt
    15901 attgtttgtg ttattcataa tgcgctaata tacaggtgtg tataagcgta attcctgttt
    15961 cccatctaaa ttgccagtga tagggtagtg ataccgtagt gatagagaaa acgggcatat
    16021 atcactaacg aaacagattg aatatcaatc gataaaaaag aaatcagtga tacagtgaca
    16081 gaggaaatgg gaaaaacttg tatgataagg ccctgttttt ttctttggta tattttatac
    16141 gatttctgaa ttttagtgca gttgccctgc aaaatggcgt atcgttcatt acgacacact
    16201 ttcttttatt ttatggataa tttttcttct ttttgccacc taaaggccgt ttttaactcc
    16261 atttccccag ccttcttctc aaaatggcag tttgttactg cagtattact tgagtaaaag
    16321 tttataagtg attataaata aggatgatat gtctgtttgc gaagaacagt aaaaaagccc
    16381 gttttcaagg ggtaaaagtt acttgttttt acttgtaact tattgggaat aaaaaagata
    16441 gtagtcagaa acaaaatgac taaaaaaacg ttcgttttaa ttcgtcattt ttactgcaca
    16501 aaaatacaac tactttttga acctgcaatc ctttccacaa atattttttc tttttctata
    16561 t
//
