## Sun Jul 21 12:03:16 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_959019875.1/GCA_959019875.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_959019875.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_959019875.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
FNPCBABE_00005	180332.JTGN01000005_gene3042	1.59e-36	137.0	COG3764@1|root,COG3764@2|Bacteria,1V3I1@1239|Firmicutes,24IU2@186801|Clostridia	186801|Clostridia	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
FNPCBABE_00006	742741.HMPREF9475_00291	5.66e-64	209.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,2215Z@1506553|Lachnoclostridium	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
FNPCBABE_00008	702459.BBPR_0282	5.22e-08	67.0	COG2304@1|root,COG4932@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria,2I2FM@201174|Actinobacteria,4CZ4I@85004|Bifidobacteriales	201174|Actinobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cna_B,FctA,PA14,VWA_2
FNPCBABE_00009	428125.CLOLEP_00213	0.0	1325.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3WGPN@541000|Ruminococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
FNPCBABE_00010	1120746.CCNL01000008_gene473	1.67e-152	448.0	COG0768@1|root,COG0768@2|Bacteria	2|Bacteria	M	penicillin binding	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
FNPCBABE_00011	428125.CLOLEP_03718	4.58e-180	526.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,3WI08@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
FNPCBABE_00013	397287.C807_02623	1.32e-52	173.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,27NIJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
FNPCBABE_00014	1121115.AXVN01000099_gene787	4.56e-186	519.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3XZ5J@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
FNPCBABE_00015	411473.RUMCAL_00604	1.15e-66	233.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3WH0E@541000|Ruminococcaceae	186801|Clostridia	O	Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
FNPCBABE_00016	702459.BBPR_1112	3.98e-89	273.0	COG2865@1|root,COG2865@2|Bacteria,2IF0U@201174|Actinobacteria,4D0I9@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00017	428125.CLOLEP_02468	4.32e-203	575.0	COG3581@1|root,COG3581@2|Bacteria,1TRVV@1239|Firmicutes,24947@186801|Clostridia,3WH15@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
FNPCBABE_00018	428125.CLOLEP_02467	0.0	1381.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,3WGW6@541000|Ruminococcaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
FNPCBABE_00020	410358.Mlab_0596	1.87e-16	82.8	arCOG07861@1|root,arCOG07861@2157|Archaea	2157|Archaea	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
FNPCBABE_00021	428125.CLOLEP_01479	1.82e-202	565.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
FNPCBABE_00022	428125.CLOLEP_01481	1.22e-150	425.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,3WGYK@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
FNPCBABE_00023	759913.SDSE_0284	2.82e-30	107.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli,1MA5A@119603|Streptococcus dysgalactiae group	91061|Bacilli	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
FNPCBABE_00025	1507.HMPREF0262_00298	1.39e-26	98.6	2BRIM@1|root,32KHM@2|Bacteria,1US5F@1239|Firmicutes,24S12@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00028	66692.ABC1368	1.4e-95	323.0	COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,1ZEU3@1386|Bacillus	91061|Bacilli	S	D5 N terminal like	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5,PriCT_1,Prim-Pol
FNPCBABE_00030	742738.HMPREF9460_00730	1.84e-15	70.1	2EK06@1|root,33DQR@2|Bacteria,1VM6B@1239|Firmicutes,24VVM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00031	1378168.N510_02622	4.73e-05	48.1	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes	1239|Firmicutes	K	Transcriptional	ansR	-	-	-	-	-	-	-	-	-	-	-	HTH_3
FNPCBABE_00032	1410670.JHXF01000004_gene1688	5.36e-120	361.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WHXB@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
FNPCBABE_00033	1507.HMPREF0262_00298	2.79e-17	75.1	2BRIM@1|root,32KHM@2|Bacteria,1US5F@1239|Firmicutes,24S12@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00034	397291.C804_01058	5.41e-19	79.7	2EGS0@1|root,33AI4@2|Bacteria,1VKKN@1239|Firmicutes,24VA8@186801|Clostridia,27T0H@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
FNPCBABE_00035	1235802.C823_05129	7.47e-14	70.5	2ET36@1|root,33KMC@2|Bacteria,1VKQN@1239|Firmicutes,24UID@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HIRAN
FNPCBABE_00041	428125.CLOLEP_01746	1.5e-62	198.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,3WJSY@541000|Ruminococcaceae	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
FNPCBABE_00042	428125.CLOLEP_01747	3.4e-154	446.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3WG8A@541000|Ruminococcaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
FNPCBABE_00043	428125.CLOLEP_01748	3.32e-35	122.0	COG2740@1|root,COG2740@2|Bacteria	2|Bacteria	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K02600,ko:K07742	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	DUF448
FNPCBABE_00044	1449063.JMLS01000018_gene5928	2.18e-13	68.2	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,26Y6Y@186822|Paenibacillaceae	91061|Bacilli	J	ribosomal protein	ylxQ	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
FNPCBABE_00045	428125.CLOLEP_01750	0.0	1013.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,3WHTD@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
FNPCBABE_00046	428125.CLOLEP_01751	1.26e-53	171.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3WJYA@541000|Ruminococcaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
FNPCBABE_00047	428125.CLOLEP_01752	2.65e-97	297.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WGKS@541000|Ruminococcaceae	186801|Clostridia	S	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
FNPCBABE_00048	1120746.CCNL01000017_gene3269	1.7e-102	309.0	COG0130@1|root,COG0130@2|Bacteria,2NP9J@2323|unclassified Bacteria	2|Bacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177,ko:K03483	-	-	-	-	ko00000,ko01000,ko03000,ko03016	-	-	iSB619.SA_RS06305	TruB-C_2,TruB_C_2,TruB_N
FNPCBABE_00049	203119.Cthe_0539	1.75e-106	313.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WH0X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
FNPCBABE_00050	1410633.JHWR01000009_gene1907	5.08e-110	366.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,27K7N@186928|unclassified Lachnospiraceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
FNPCBABE_00051	562743.JH976442_gene682	6.39e-62	200.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,4HDD2@91061|Bacilli	91061|Bacilli	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
FNPCBABE_00052	246199.CUS_5839	8.29e-59	201.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia,3WJ10@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase- DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
FNPCBABE_00053	632245.CLP_0027	4.53e-165	533.0	COG0366@1|root,COG1501@1|root,COG0366@2|Bacteria,COG1501@2|Bacteria,1TP9E@1239|Firmicutes,248DX@186801|Clostridia,36DSD@31979|Clostridiaceae	186801|Clostridia	G	Alpha-amylase domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,CBM26
FNPCBABE_00054	522772.Dacet_0298	2.16e-60	192.0	COG1853@1|root,COG1853@2|Bacteria,2GFRT@200930|Deferribacteres	200930|Deferribacteres	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
FNPCBABE_00055	742765.HMPREF9457_03735	6.05e-68	207.0	COG1598@1|root,COG1598@2|Bacteria,1VAII@1239|Firmicutes,24I04@186801|Clostridia	186801|Clostridia	S	HicB family	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB,HicB_lk_antitox
FNPCBABE_00056	428125.CLOLEP_03644	2.34e-240	667.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3WGG9@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
FNPCBABE_00057	1120746.CCNL01000017_gene3125	2.82e-231	648.0	COG0165@1|root,COG0165@2|Bacteria,2NP70@2323|unclassified Bacteria	2|Bacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,4.3.2.1	ko:K01755,ko:K14681	ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230	M00028,M00029,M00844,M00845	R00259,R01086	RC00004,RC00064,RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Acetyltransf_1,Lyase_1
FNPCBABE_00058	1121334.KB911067_gene360	2.73e-181	512.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,3WGZJ@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
FNPCBABE_00059	428125.CLOLEP_03649	3.01e-181	517.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,3WGSI@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
FNPCBABE_00060	428125.CLOLEP_03650	8.82e-150	427.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,3WGF0@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10565	AA_kinase
FNPCBABE_00061	742733.HMPREF9469_01580	3.87e-34	123.0	COG0454@1|root,COG0456@2|Bacteria,1V4GU@1239|Firmicutes,24IME@186801|Clostridia,2209N@1506553|Lachnoclostridium	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	RimI	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
FNPCBABE_00062	428125.CLOLEP_03651	2.96e-167	483.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3WGQA@541000|Ruminococcaceae	186801|Clostridia	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iHN637.CLJU_RS10560	Aminotran_3
FNPCBABE_00063	428125.CLOLEP_03652	1.77e-167	474.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,3WG9U@541000|Ruminococcaceae	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
FNPCBABE_00065	1262915.BN574_01425	4.65e-39	143.0	COG3503@1|root,COG3503@2|Bacteria,1V8H3@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
FNPCBABE_00066	1209989.TepiRe1_0942	4.57e-96	288.0	COG1511@1|root,COG1511@2|Bacteria,1TPFN@1239|Firmicutes,24DWU@186801|Clostridia	186801|Clostridia	S	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
FNPCBABE_00067	1408303.JNJJ01000024_gene2951	1.96e-88	268.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4IPMF@91061|Bacilli,1ZRD4@1386|Bacillus	91061|Bacilli	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
FNPCBABE_00068	1385514.N782_12495	8.89e-38	132.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,MazE_antitoxin
FNPCBABE_00071	1384066.JAGT01000001_gene872	1.58e-129	375.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,3WGBQ@541000|Ruminococcaceae	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
FNPCBABE_00073	1105031.HMPREF1141_2184	2.08e-136	397.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,36FBU@31979|Clostridiaceae	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
FNPCBABE_00074	428125.CLOLEP_00077	1.01e-186	529.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,3WH82@541000|Ruminococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
FNPCBABE_00075	1105031.HMPREF1141_3189	0.0	941.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,36DJ7@31979|Clostridiaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
FNPCBABE_00076	1120746.CCNL01000017_gene3180	9.3e-45	154.0	COG0576@1|root,COG0576@2|Bacteria,2NPSS@2323|unclassified Bacteria	2|Bacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
FNPCBABE_00077	1321778.HMPREF1982_04002	2.76e-52	183.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,267M7@186813|unclassified Clostridiales	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
FNPCBABE_00079	1408436.JHXY01000049_gene257	9.82e-113	327.0	COG2184@1|root,COG2184@2|Bacteria,1TPUZ@1239|Firmicutes,248XF@186801|Clostridia,25W8Z@186806|Eubacteriaceae	186801|Clostridia	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Bro-N,Fic
FNPCBABE_00080	1033837.WANG_0423	3.99e-56	184.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,3F3JG@33958|Lactobacillaceae	91061|Bacilli	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
FNPCBABE_00082	428125.CLOLEP_00268	3.25e-94	278.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,3WI2S@541000|Ruminococcaceae	186801|Clostridia	C	Hydrolyase, tartrate beta subunit fumarate domain protein, Fe-S type	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
FNPCBABE_00083	428125.CLOLEP_00267	4.11e-143	410.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3WH30@541000|Ruminococcaceae	186801|Clostridia	C	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
FNPCBABE_00084	394503.Ccel_0246	3.08e-126	363.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,36DGI@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	-	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
FNPCBABE_00085	1291050.JAGE01000001_gene1916	7.1e-137	412.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,3WH1I@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
FNPCBABE_00086	632245.CLP_3839	3.08e-49	176.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,36EKJ@31979|Clostridiaceae	186801|Clostridia	S	N-methylation of lysine residues in flagellin K00599	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
FNPCBABE_00087	445973.CLOBAR_00924	4.71e-17	76.3	2E7YJ@1|root,33A8K@2|Bacteria,1VQP8@1239|Firmicutes,24QA7@186801|Clostridia,25U19@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00089	1120746.CCNL01000017_gene3190	2.66e-26	99.4	COG0268@1|root,COG0268@2|Bacteria	2|Bacteria	J	rRNA binding	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
FNPCBABE_00090	697329.Rumal_0372	1.07e-132	380.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,3WGSY@541000|Ruminococcaceae	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
FNPCBABE_00091	1304866.K413DRAFT_0121	1.21e-124	361.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,36H9K@31979|Clostridiaceae	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
FNPCBABE_00092	509191.AEDB02000098_gene3535	1.36e-241	669.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,3WGIV@541000|Ruminococcaceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
FNPCBABE_00093	1226325.HMPREF1548_04439	9.18e-105	311.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,36EKM@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
FNPCBABE_00094	556261.HMPREF0240_04079	4.25e-134	392.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,36ERC@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
FNPCBABE_00095	610130.Closa_3621	7.76e-87	260.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,21YT9@1506553|Lachnoclostridium	186801|Clostridia	EH	Peptidase C26	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
FNPCBABE_00096	180332.JTGN01000016_gene992	2.6e-215	612.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
FNPCBABE_00097	1282887.AUJG01000005_gene174	1.67e-145	430.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
FNPCBABE_00098	585394.RHOM_02225	6.87e-124	367.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
FNPCBABE_00099	537013.CLOSTMETH_02396	2.59e-222	632.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,25AZ5@186801|Clostridia,3WH41@541000|Ruminococcaceae	186801|Clostridia	I	AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,Cupin_2,HTH_3
FNPCBABE_00100	877411.JMMA01000002_gene1715	2.17e-175	501.0	COG1160@1|root,COG1160@2|Bacteria,1UI84@1239|Firmicutes,25EDI@186801|Clostridia,3WSKW@541000|Ruminococcaceae	186801|Clostridia	S	Ferrous iron transport protein B	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
FNPCBABE_00101	585394.RHOM_04680	1.35e-272	754.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia	186801|Clostridia	C	biosynthesis protein ThiH	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
FNPCBABE_00102	411489.CLOL250_01571	3e-157	451.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,36DIQ@31979|Clostridiaceae	186801|Clostridia	C	radical SAM domain protein	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
FNPCBABE_00104	180332.JTGN01000025_gene1558	2.94e-93	290.0	COG1594@1|root,COG1594@2|Bacteria,1UHVH@1239|Firmicutes,25E4D@186801|Clostridia	186801|Clostridia	K	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00105	397290.C810_03926	1.03e-145	428.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,27ICK@186928|unclassified Lachnospiraceae	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1
FNPCBABE_00106	689781.AUJX01000037_gene2163	4.17e-31	122.0	2EN4B@1|root,33FSE@2|Bacteria,1VPF9@1239|Firmicutes,24SXK@186801|Clostridia,2PS4P@265975|Oribacterium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tim44,zinc_ribbon_2
FNPCBABE_00107	1514668.JOOA01000002_gene3012	0.0	895.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,3WGX1@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
FNPCBABE_00108	1121334.KB911078_gene1208	1.14e-198	563.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,3WHGY@541000|Ruminococcaceae	186801|Clostridia	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
FNPCBABE_00109	428125.CLOLEP_01229	4.36e-85	251.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3WII3@541000|Ruminococcaceae	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
FNPCBABE_00110	118173.KB235910_gene4709	2.25e-36	136.0	COG2894@1|root,COG2894@2|Bacteria,1G2A5@1117|Cyanobacteria,1H745@1150|Oscillatoriales	1117|Cyanobacteria	D	Belongs to the ParA family	minD	GO:0000910,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0032506,GO:0036214,GO:0051179,GO:0051301,GO:0061640	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA,ParA
FNPCBABE_00111	1105031.HMPREF1141_1472	9.47e-177	528.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,36DW0@31979|Clostridiaceae	186801|Clostridia	M	Penicillin-binding Protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
FNPCBABE_00113	1507.HMPREF0262_01942	5.22e-29	117.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,36EKP@31979|Clostridiaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
FNPCBABE_00114	428125.CLOLEP_01234	1.77e-184	519.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,3WGF8@541000|Ruminococcaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
FNPCBABE_00115	428125.CLOLEP_01236	2.65e-59	187.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,3WK0P@541000|Ruminococcaceae	186801|Clostridia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
FNPCBABE_00116	877411.JMMA01000002_gene2088	4.88e-137	425.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,3WH8K@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase U32	ydcP	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
FNPCBABE_00118	1121334.KB911078_gene1195	6.38e-213	614.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,3WGCV@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain protein	apu	-	2.4.1.25,3.2.1.133,3.2.1.135,3.2.1.20,3.2.1.54	ko:K00705,ko:K01187,ko:K01208	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R02112,R03122,R05196,R06087,R06088,R11262	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH13,GH31,GH77	-	Alpha-amylase,Alpha-amylase_N,Glyco_hydro_77,Malt_amylase_C
FNPCBABE_00119	1160721.RBI_I00554	2.09e-220	629.0	COG2197@1|root,COG2197@2|Bacteria,1U63E@1239|Firmicutes,24F84@186801|Clostridia,3WKYE@541000|Ruminococcaceae	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00120	471875.RUMLAC_00727	9.65e-112	358.0	29URU@1|root,30G3W@2|Bacteria,1UF59@1239|Firmicutes,25K62@186801|Clostridia,3WP2M@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00122	428125.CLOLEP_01250	0.0	1074.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,3WGW0@541000|Ruminococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
FNPCBABE_00123	1232666.JANE01000070_gene1317	5.03e-29	110.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli,4GYXX@90964|Staphylococcaceae	91061|Bacilli	S	Acyl-ACP thioesterase	yneP	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
FNPCBABE_00124	428125.CLOLEP_01253	0.0	1001.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,3WGZ0@541000|Ruminococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
FNPCBABE_00126	428125.CLOLEP_01255	4.52e-31	112.0	2E36Q@1|root,32Y6E@2|Bacteria,1VEZV@1239|Firmicutes,24MQP@186801|Clostridia,3WKJK@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF370)	-	-	-	-	-	-	-	-	-	-	-	-	DUF370
FNPCBABE_00127	1235797.C816_01896	2.26e-86	273.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,2N6MG@216572|Oscillospiraceae	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
FNPCBABE_00128	1519439.JPJG01000095_gene930	6.04e-25	94.7	COG2501@1|root,COG2501@2|Bacteria,1TU9W@1239|Firmicutes,25NDU@186801|Clostridia,2N7QR@216572|Oscillospiraceae	186801|Clostridia	S	S4 domain	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
FNPCBABE_00129	428125.CLOLEP_01258	1.78e-141	416.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,3WGZ2@541000|Ruminococcaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
FNPCBABE_00130	428125.CLOLEP_01262	4.13e-199	566.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,3WGJH@541000|Ruminococcaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
FNPCBABE_00131	742735.HMPREF9467_03124	0.0	920.0	COG0741@1|root,COG0741@2|Bacteria,1V3F0@1239|Firmicutes,249C4@186801|Clostridia,222B9@1506553|Lachnoclostridium	186801|Clostridia	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Lysozyme_like
FNPCBABE_00132	1321372.AQQB01000003_gene1507	5.93e-189	524.0	COG4509@1|root,COG4509@2|Bacteria,1TRWN@1239|Firmicutes,4HFQW@91061|Bacilli	91061|Bacilli	S	sortase, SrtB family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
FNPCBABE_00133	1321372.AQQB01000003_gene1506	0.0	1519.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,4HUB9@91061|Bacilli,1WSV1@1307|Streptococcus suis	91061|Bacilli	U	'COG3451 Type IV secretory pathway, VirB4 components'	XK27_00545	-	-	-	-	-	-	-	-	-	-	-	DUF87
FNPCBABE_00134	1321372.AQQB01000003_gene1505	4.25e-82	243.0	COG3451@1|root,COG3451@2|Bacteria,1V6F7@1239|Firmicutes	1239|Firmicutes	U	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
FNPCBABE_00136	1321372.AQQB01000003_gene1504	1.44e-191	532.0	2DB6V@1|root,2Z7IJ@2|Bacteria,1TRNS@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TrbL
FNPCBABE_00137	1321372.AQQB01000003_gene1503	1.89e-75	226.0	2DMPF@1|root,32SVU@2|Bacteria,1VA0M@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00138	1321372.AQQB01000003_gene1502	0.0	1182.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,4H9ZN@91061|Bacilli,1WU5I@1307|Streptococcus suis	91061|Bacilli	U	Type IV secretory system Conjugative DNA transfer	traK	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
FNPCBABE_00139	1321372.AQQB01000003_gene1501	2.16e-39	130.0	2ENF6@1|root,33G2N@2|Bacteria,1VND9@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00140	1321372.AQQB01000003_gene1500	8.13e-206	570.0	COG4227@1|root,COG4227@2|Bacteria,1V3C4@1239|Firmicutes	1239|Firmicutes	L	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00141	1321372.AQQB01000003_gene1499	7.71e-164	461.0	295P2@1|root,2ZT0F@2|Bacteria,1TT96@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
FNPCBABE_00142	411468.CLOSCI_02608	1.66e-260	717.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,247ME@186801|Clostridia,21XNK@1506553|Lachnoclostridium	186801|Clostridia	L	COG COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Trans_reg_C,Transposase_20
FNPCBABE_00143	1321372.AQQB01000003_gene1498	0.0	887.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes	1239|Firmicutes	U	Relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
FNPCBABE_00144	1321372.AQQB01000003_gene1497	2.45e-75	225.0	2CDK1@1|root,32G0D@2|Bacteria,1V6YH@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MobC
FNPCBABE_00145	1321372.AQQB01000003_gene1496	4.61e-222	612.0	COG4734@1|root,COG4734@2|Bacteria,1VCY1@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF3846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3846
FNPCBABE_00146	1321372.AQQB01000003_gene1495	1.11e-235	647.0	COG0358@1|root,COG0358@2|Bacteria,1TSIU@1239|Firmicutes	1239|Firmicutes	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3991,Toprim_2
FNPCBABE_00148	742735.HMPREF9467_03142	0.0	4915.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia,21Y2C@1506553|Lachnoclostridium	186801|Clostridia	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,SNF2_N
FNPCBABE_00149	742735.HMPREF9467_03143	2.82e-168	469.0	29XBT@1|root,30J1H@2|Bacteria,1UK6U@1239|Firmicutes,25FNG@186801|Clostridia,221FG@1506553|Lachnoclostridium	186801|Clostridia	S	Domain of unknown function (DUF4314)	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00150	1321372.AQQB01000003_gene1491	8.99e-133	376.0	2ECXH@1|root,336UQ@2|Bacteria,1VT65@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00151	1321372.AQQB01000003_gene1490	4.16e-46	148.0	2C6KJ@1|root,33B28@2|Bacteria,1VKZ3@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00152	742735.HMPREF9467_03146	7.28e-138	390.0	28MNI@1|root,2ZAY2@2|Bacteria,1TQI0@1239|Firmicutes,24BEQ@186801|Clostridia,220DB@1506553|Lachnoclostridium	742735.HMPREF9467_03146|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00153	742735.HMPREF9467_03147	3.76e-67	203.0	2BAZG@1|root,324FD@2|Bacteria,1UQQX@1239|Firmicutes,258H7@186801|Clostridia,223FI@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00155	742735.HMPREF9467_03149	0.0	2720.0	COG4932@1|root,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,2492K@186801|Clostridia,2246F@1506553|Lachnoclostridium	186801|Clostridia	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Sortase
FNPCBABE_00156	742735.HMPREF9467_03150	1.27e-89	271.0	2CAZ8@1|root,2ZRZD@2|Bacteria,1W2TG@1239|Firmicutes,254UZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00157	742735.HMPREF9467_03151	5.09e-198	551.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,221X1@1506553|Lachnoclostridium	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
FNPCBABE_00158	742735.HMPREF9467_03152	1.18e-188	525.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,21ZKM@1506553|Lachnoclostridium	186801|Clostridia	D	COG COG1192 ATPases involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
FNPCBABE_00159	642492.Clole_1999	1.5e-166	478.0	COG0025@1|root,COG0025@2|Bacteria,1UHUI@1239|Firmicutes,25E2Y@186801|Clostridia	186801|Clostridia	P	Transporter, CPA2 family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
FNPCBABE_00160	742735.HMPREF9467_03153	2.19e-31	110.0	2DIMN@1|root,303NN@2|Bacteria,1TUX8@1239|Firmicutes,25I11@186801|Clostridia,223GZ@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00161	742735.HMPREF9467_03154	0.0	958.0	COG1996@1|root,COG1996@2|Bacteria,1UZSK@1239|Firmicutes,24A4V@186801|Clostridia	186801|Clostridia	K	Probable Zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4379
FNPCBABE_00162	742735.HMPREF9467_03155	3.62e-135	384.0	COG0671@1|root,COG0671@2|Bacteria,1V0H7@1239|Firmicutes,25D3K@186801|Clostridia	186801|Clostridia	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
FNPCBABE_00163	742735.HMPREF9467_03156	2.06e-130	371.0	COG1476@1|root,COG1476@2|Bacteria,1V3Q1@1239|Firmicutes,24HI5@186801|Clostridia,220M0@1506553|Lachnoclostridium	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
FNPCBABE_00164	478749.BRYFOR_06776	3.2e-277	773.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
FNPCBABE_00165	1120746.CCNL01000017_gene3148	1.71e-49	163.0	COG0782@1|root,COG0782@2|Bacteria,2NPT2@2323|unclassified Bacteria	2|Bacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624,ko:K06140	-	-	-	-	ko00000,ko03000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
FNPCBABE_00167	428125.CLOLEP_01623	7.17e-51	185.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,3WGCB@541000|Ruminococcaceae	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
FNPCBABE_00168	1120746.CCNL01000017_gene3151	2.52e-90	278.0	COG2177@1|root,COG2177@2|Bacteria	2|Bacteria	D	cell division	ftsX	GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531	-	ko:K09811,ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
FNPCBABE_00169	1507.HMPREF0262_03282	1.05e-96	289.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,36DHJ@31979|Clostridiaceae	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
FNPCBABE_00170	428125.CLOLEP_01620	3.19e-216	602.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia,3WHDV@541000|Ruminococcaceae	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	Diacid_rec,HTH_30
FNPCBABE_00171	1120746.CCNL01000017_gene3154	2.19e-204	572.0	COG3842@1|root,COG3842@2|Bacteria,2NNU0@2323|unclassified Bacteria	2|Bacteria	E	ATPases associated with a variety of cellular activities	msmX	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
FNPCBABE_00172	537013.CLOSTMETH_01071	8.85e-70	221.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,3WHTI@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
FNPCBABE_00174	411461.DORFOR_01437	6.49e-41	145.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,27VI1@189330|Dorea	186801|Clostridia	S	HAD-hyrolase-like	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
FNPCBABE_00175	756499.Desde_2535	1.3e-17	80.1	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,262M7@186807|Peptococcaceae	186801|Clostridia	S	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
FNPCBABE_00176	428125.CLOLEP_03768	8.19e-209	583.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,3WG9I@541000|Ruminococcaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
FNPCBABE_00178	1120746.CCNL01000008_gene579	2.33e-158	451.0	COG3958@1|root,COG3958@2|Bacteria,2NQFH@2323|unclassified Bacteria	2|Bacteria	G	Transketolase, pyrimidine binding domain	tklB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
FNPCBABE_00179	1120746.CCNL01000008_gene578	2.11e-138	397.0	COG3959@1|root,COG3959@2|Bacteria,2NP12@2323|unclassified Bacteria	2|Bacteria	G	Transketolase, thiamine diphosphate binding domain	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
FNPCBABE_00180	428125.CLOLEP_02571	1.85e-83	257.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,3WHZV@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
FNPCBABE_00181	1410638.JHXJ01000016_gene228	4.15e-38	137.0	COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,249YQ@186801|Clostridia,3WK03@541000|Ruminococcaceae	186801|Clostridia	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
FNPCBABE_00182	1410661.JNKW01000002_gene1616	9.31e-70	227.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
FNPCBABE_00183	428125.CLOLEP_01772	0.0	1852.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,3WGRN@541000|Ruminococcaceae	186801|Clostridia	F	phosphoribosylformylglycinamidine synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
FNPCBABE_00184	471875.RUMLAC_01710	6.17e-56	186.0	COG0546@1|root,COG0546@2|Bacteria,1V3MH@1239|Firmicutes,25F06@186801|Clostridia	186801|Clostridia	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
FNPCBABE_00185	411463.EUBVEN_02823	3.37e-101	306.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,25VNT@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
FNPCBABE_00187	478749.BRYFOR_09532	8.23e-14	76.6	COG3279@1|root,COG3279@2|Bacteria,1V7ED@1239|Firmicutes,24K36@186801|Clostridia	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
FNPCBABE_00188	1235793.C809_04307	1.59e-83	270.0	COG3290@1|root,COG3290@2|Bacteria,1V0KZ@1239|Firmicutes,25BG0@186801|Clostridia,27TX7@186928|unclassified Lachnospiraceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
FNPCBABE_00189	931626.Awo_c23170	2.81e-29	126.0	COG3942@1|root,COG3942@2|Bacteria,1VFAV@1239|Firmicutes,25BXN@186801|Clostridia	186801|Clostridia	N	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHAP,CW_binding_1,GBS_Bsp-like,RicinB_lectin_2
FNPCBABE_00190	749222.Nitsa_1646	2.37e-24	97.8	2CCSR@1|root,32RWC@2|Bacteria,1MZFP@1224|Proteobacteria,42U6B@68525|delta/epsilon subdivisions,2YQ44@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
FNPCBABE_00192	428125.CLOLEP_03923	6.56e-229	643.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,3WHAH@541000|Ruminococcaceae	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
FNPCBABE_00193	1096546.WYO_0710	2.08e-11	70.5	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2TRDB@28211|Alphaproteobacteria,1JRDW@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM Lytic transglycosylase catalytic	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
FNPCBABE_00194	1484460.JSWG01000015_gene1099	1.23e-15	79.3	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1I1XH@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
FNPCBABE_00195	428125.CLOLEP_03920	1.01e-134	394.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,3WGIY@541000|Ruminococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
FNPCBABE_00196	428125.CLOLEP_03918	2.64e-176	500.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3WGA4@541000|Ruminococcaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
FNPCBABE_00197	643648.Slip_2351	8.88e-17	73.6	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,42K83@68298|Syntrophomonadaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
FNPCBABE_00198	698758.AXY_19270	5.2e-41	145.0	28JM5@1|root,2Z9DQ@2|Bacteria,1TS2D@1239|Firmicutes,4HRPU@91061|Bacilli	91061|Bacilli	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00199	545694.TREPR_3601	5.97e-18	90.1	COG1752@1|root,COG1752@2|Bacteria,2J6JW@203691|Spirochaetes	203691|Spirochaetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
FNPCBABE_00200	1232453.BAIF02000102_gene3673	3.94e-36	149.0	2AHKI@1|root,317YB@2|Bacteria,1V965@1239|Firmicutes,24MIW@186801|Clostridia,26BP7@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
FNPCBABE_00201	1121334.KB911072_gene2601	7.91e-287	809.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
FNPCBABE_00202	290402.Cbei_0271	2.49e-06	53.9	COG1309@1|root,COG1309@2|Bacteria,1V59K@1239|Firmicutes,24BGP@186801|Clostridia,36HTF@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
FNPCBABE_00203	1226325.HMPREF1548_04814	5.66e-155	451.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia,36DM6@31979|Clostridiaceae	186801|Clostridia	P	Transporter, CPA2 family	napA	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
FNPCBABE_00204	457570.Nther_2650	2.01e-10	69.3	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia	186801|Clostridia	EJ	L-asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
FNPCBABE_00205	931276.Cspa_c25100	6.66e-35	126.0	COG3467@1|root,COG3467@2|Bacteria,1V7MR@1239|Firmicutes,25B09@186801|Clostridia,36W93@31979|Clostridiaceae	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
FNPCBABE_00206	428125.CLOLEP_01062	4.45e-210	592.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,3WK6T@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
FNPCBABE_00208	1235799.C818_03247	7.39e-205	569.0	COG3177@1|root,COG3177@2|Bacteria,1V3AX@1239|Firmicutes,248VF@186801|Clostridia,27NE7@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
FNPCBABE_00209	764299.STRIC_1753	0.000624	42.7	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,4HNVM@91061|Bacilli	91061|Bacilli	K	Transcriptional	lanR	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
FNPCBABE_00210	1345695.CLSA_c26760	2.77e-11	64.3	2DETX@1|root,2ZP8Z@2|Bacteria,1W4UB@1239|Firmicutes,24VW4@186801|Clostridia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36
FNPCBABE_00211	1340434.AXVA01000004_gene2579	4.21e-05	48.9	COG0454@1|root,COG0454@2|Bacteria,1V78S@1239|Firmicutes,4HJMM@91061|Bacilli,1ZIJF@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
FNPCBABE_00212	1449050.JNLE01000003_gene2028	2.41e-217	643.0	COG0366@1|root,COG3291@1|root,COG0366@2|Bacteria,COG3291@2|Bacteria,1V0U1@1239|Firmicutes,24ZQ4@186801|Clostridia	186801|Clostridia	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
FNPCBABE_00213	1214166.ALLG01000001_gene1573	5.46e-12	77.8	COG0366@1|root,COG5492@1|root,COG0366@2|Bacteria,COG5492@2|Bacteria,1V0U1@1239|Firmicutes,4HV3E@91061|Bacilli	91061|Bacilli	G	alpha-amylase	aml1	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM26,CBM53,CBM_35,CHB_HEX_C_1
FNPCBABE_00214	428125.CLOLEP_03258	9.08e-207	585.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,3WGT0@541000|Ruminococcaceae	186801|Clostridia	L	ATPase, AAA family	yrvN	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
FNPCBABE_00215	1151292.QEW_3406	1.64e-53	202.0	COG2247@1|root,COG4870@1|root,COG2247@2|Bacteria,COG4870@2|Bacteria,1TVCW@1239|Firmicutes,25B7E@186801|Clostridia,25S9K@186804|Peptostreptococcaceae	186801|Clostridia	M	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,CW_binding_2,Flg_new,Peptidase_C1
FNPCBABE_00216	428125.CLOLEP_02521	2.35e-108	323.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,3WGVA@541000|Ruminococcaceae	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
FNPCBABE_00217	411489.CLOL250_02890	2.04e-21	102.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,36F21@31979|Clostridiaceae	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
FNPCBABE_00218	1160721.RBI_I00829	4.76e-188	540.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,3WGU8@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
FNPCBABE_00219	1280679.ATVX01000008_gene2065	2.53e-136	406.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,4BW25@830|Butyrivibrio	186801|Clostridia	P	TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
FNPCBABE_00220	641112.ACOK01000105_gene633	6.05e-256	711.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WGEA@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
FNPCBABE_00221	641112.ACOK01000105_gene634	2.97e-155	441.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,3WGGC@541000|Ruminococcaceae	186801|Clostridia	C	domain protein	nfnA	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
FNPCBABE_00222	428125.CLOLEP_02890	1.66e-139	406.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,3WH12@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
FNPCBABE_00223	658086.HMPREF0994_05067	1.41e-78	239.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,27MTS@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
FNPCBABE_00224	742765.HMPREF9457_02977	3.83e-24	102.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,27WBF@189330|Dorea	186801|Clostridia	K	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
FNPCBABE_00227	428125.CLOLEP_01608	1.35e-75	236.0	28P0Q@1|root,2ZBX8@2|Bacteria,1V22P@1239|Firmicutes,248XV@186801|Clostridia,3WJK7@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00228	1121334.KB911071_gene2146	2.66e-98	296.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,3WGHY@541000|Ruminococcaceae	186801|Clostridia	L	8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
FNPCBABE_00229	1345697.M493_16510	1.2e-10	71.6	COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,1TT2K@1239|Firmicutes,4ISYS@91061|Bacilli,1WF59@129337|Geobacillus	91061|Bacilli	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,PG_binding_1
FNPCBABE_00230	428125.CLOLEP_02036	1.69e-149	439.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,3WH9K@541000|Ruminococcaceae	186801|Clostridia	S	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
FNPCBABE_00231	1203606.HMPREF1526_00041	1.85e-109	330.0	COG1086@1|root,COG1086@2|Bacteria,1U3RH@1239|Firmicutes,24K9I@186801|Clostridia,36KEF@31979|Clostridiaceae	186801|Clostridia	GM	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
FNPCBABE_00233	428125.CLOLEP_01183	8.06e-79	243.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3WISD@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
FNPCBABE_00235	428125.CLOLEP_01611	5.61e-103	306.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,3WGPU@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
FNPCBABE_00237	471856.Jden_2236	4.64e-05	52.0	COG0494@1|root,COG2062@1|root,COG0494@2|Bacteria,COG2062@2|Bacteria,2GNRV@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the NUDIX hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
FNPCBABE_00238	428125.CLOLEP_02548	1.91e-52	187.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,24GSB@186801|Clostridia,3WHJM@541000|Ruminococcaceae	186801|Clostridia	S	DHHW protein	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
FNPCBABE_00239	428125.CLOLEP_00283	5.8e-205	579.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,3WGG5@541000|Ruminococcaceae	186801|Clostridia	EK	Aminotransferase, class I	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
FNPCBABE_00240	428125.CLOLEP_00284	1.18e-182	514.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
FNPCBABE_00241	1121296.JONJ01000005_gene1237	4.36e-47	180.0	COG4346@1|root,COG5542@1|root,COG4346@2|Bacteria,COG5542@2|Bacteria,1TSHX@1239|Firmicutes,24AN2@186801|Clostridia	186801|Clostridia	M	PFAM glycosyl transferase family 39	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT,PMT_2,PMT_4TMC
FNPCBABE_00242	1123313.ATUT01000016_gene634	4.25e-175	504.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes	1239|Firmicutes	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
FNPCBABE_00243	411460.RUMTOR_01409	9.41e-64	228.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia,3XYKE@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
FNPCBABE_00244	1280689.AUJC01000001_gene2401	1.39e-47	162.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia,36JHH@31979|Clostridiaceae	186801|Clostridia	G	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
FNPCBABE_00245	1391646.AVSU01000026_gene2342	4.64e-115	352.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,25SUZ@186804|Peptostreptococcaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
FNPCBABE_00246	1121334.KB911067_gene247	2.84e-161	464.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,3WGQB@541000|Ruminococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
FNPCBABE_00247	428125.CLOLEP_03881	1.96e-210	587.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,3WGD1@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
FNPCBABE_00248	1160721.RBI_I00681	4.93e-158	450.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,3WH6X@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
FNPCBABE_00249	1336241.JAEB01000005_gene1441	1.18e-157	451.0	COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,247MU@186801|Clostridia,25V7F@186806|Eubacteriaceae	186801|Clostridia	E	HMGL-like	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
FNPCBABE_00250	1120746.CCNL01000017_gene2970	4.85e-191	543.0	COG0044@1|root,COG0044@2|Bacteria,2NNWP@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
FNPCBABE_00252	411473.RUMCAL_01644	3.4e-299	833.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3WGUC@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
FNPCBABE_00253	1410670.JHXF01000001_gene2655	8.15e-246	699.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,3WGZ4@541000|Ruminococcaceae	186801|Clostridia	GM	Polysaccharide biosynthesis protein	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
FNPCBABE_00254	742733.HMPREF9469_01977	1.15e-44	166.0	COG1215@1|root,COG1408@1|root,COG1215@2|Bacteria,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,21XRU@1506553|Lachnoclostridium	186801|Clostridia	M	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
FNPCBABE_00255	1408823.AXUS01000007_gene2970	8.07e-12	73.6	COG2207@1|root,COG3664@1|root,COG2207@2|Bacteria,COG3664@2|Bacteria,1TQGI@1239|Firmicutes,2490Q@186801|Clostridia	186801|Clostridia	G	PFAM glycoside hydrolase family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	AraC_binding,Cupin_2,Glyco_hydro_39,HTH_18
FNPCBABE_00256	1514668.JOOA01000002_gene2327	5.04e-61	199.0	COG0062@1|root,COG0062@2|Bacteria,1VE29@1239|Firmicutes,24JS0@186801|Clostridia,3WJPQ@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX	nnrE	-	5.1.99.6	ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	YjeF_N
FNPCBABE_00257	1410617.JHXH01000001_gene806	1.31e-45	159.0	28RJ8@1|root,2ZDY4@2|Bacteria,1V64R@1239|Firmicutes,25GI1@186801|Clostridia,3WSFI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00258	1469948.JPNB01000001_gene447	4.04e-88	279.0	2F3Y4@1|root,33WQ6@2|Bacteria,1UKAG@1239|Firmicutes,24JVD@186801|Clostridia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
FNPCBABE_00260	428125.CLOLEP_03715	3.31e-55	191.0	COG0110@1|root,COG0110@2|Bacteria,1V23V@1239|Firmicutes,24GGM@186801|Clostridia,3WJ74@541000|Ruminococcaceae	186801|Clostridia	S	COG COG0110 Acetyltransferase (isoleucine patch superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
FNPCBABE_00261	702450.CUW_1624	7.26e-65	218.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,3VPKC@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
FNPCBABE_00262	697329.Rumal_1534	1.83e-48	187.0	COG5279@1|root,COG5279@2|Bacteria	2|Bacteria	D	protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,LRR_5,Transglut_core
FNPCBABE_00263	411473.RUMCAL_03074	2.03e-28	105.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,3WKHX@541000|Ruminococcaceae	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
FNPCBABE_00264	435591.BDI_1838	7.13e-193	546.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,2FMKJ@200643|Bacteroidia,22ZYB@171551|Porphyromonadaceae	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
FNPCBABE_00265	1410638.JHXJ01000001_gene1756	9.52e-12	64.3	arCOG12654@1|root,330YI@2|Bacteria,1VGQU@1239|Firmicutes,24N61@186801|Clostridia,3WQ3R@541000|Ruminococcaceae	186801|Clostridia	S	HIRAN domain	-	-	-	-	-	-	-	-	-	-	-	-	HIRAN
FNPCBABE_00267	663952.SDD27957_04550	3.52e-28	117.0	COG2207@1|root,COG2207@2|Bacteria,1UZG6@1239|Firmicutes,4HCQS@91061|Bacilli,1M9XV@119603|Streptococcus dysgalactiae group	91061|Bacilli	K	AraC-type DNA-binding domain-containing proteins	bglC	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
FNPCBABE_00268	1232443.BAIA02000143_gene1661	1.13e-117	350.0	COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,247S2@186801|Clostridia,26844@186813|unclassified Clostridiales	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
FNPCBABE_00269	457412.RSAG_02538	3.42e-37	142.0	COG0679@1|root,COG0679@2|Bacteria,1UYFH@1239|Firmicutes,24AI3@186801|Clostridia,3WRXJ@541000|Ruminococcaceae	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
FNPCBABE_00270	471875.RUMLAC_02541	0.000283	47.4	2DQHF@1|root,336V9@2|Bacteria,1VIX0@1239|Firmicutes,24T9J@186801|Clostridia,3WKRP@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00271	658088.HMPREF0987_02627	7.28e-211	596.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,27I6Q@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
FNPCBABE_00272	428125.CLOLEP_01967	0.0	935.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3WGAB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
FNPCBABE_00273	428125.CLOLEP_01968	8.56e-186	525.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,3WGG1@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
FNPCBABE_00275	1507.HMPREF0262_01420	2.58e-39	135.0	COG2315@1|root,COG2315@2|Bacteria,1V4K7@1239|Firmicutes,25AZA@186801|Clostridia,36W6P@31979|Clostridiaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
FNPCBABE_00277	1105031.HMPREF1141_1414	8.01e-117	347.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,36E02@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
FNPCBABE_00278	428125.CLOLEP_03259	5.39e-250	692.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3WGJK@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
FNPCBABE_00280	1460634.JCM19037_1588	1.02e-14	72.0	COG0758@1|root,COG0758@2|Bacteria,1VNFT@1239|Firmicutes,4HZZP@91061|Bacilli	91061|Bacilli	LU	Protein of unknown function (DUF2493)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2493
FNPCBABE_00281	1487921.DP68_09690	4.19e-07	56.2	COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,24D98@186801|Clostridia,36I34@31979|Clostridiaceae	186801|Clostridia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2,SNARE_assoc
FNPCBABE_00282	1507.HMPREF0262_02714	5.11e-129	379.0	COG0183@1|root,COG0183@2|Bacteria,1UHVW@1239|Firmicutes,248BM@186801|Clostridia,36DQK@31979|Clostridiaceae	186801|Clostridia	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
FNPCBABE_00283	1094508.Tsac_2492	2.19e-29	129.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia,42EY6@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM VanW family protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
FNPCBABE_00284	428125.CLOLEP_00385	6.9e-92	288.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia,3WIYK@541000|Ruminococcaceae	186801|Clostridia	M	UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
FNPCBABE_00285	509191.AEDB02000042_gene4898	1.41e-20	101.0	COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,24B76@186801|Clostridia,3WGCD@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Dockerin_1,Serpin
FNPCBABE_00286	428125.CLOLEP_01561	3.1e-278	769.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WGJQ@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
FNPCBABE_00287	1120746.CCNL01000011_gene1544	0.0	927.0	COG0008@1|root,COG0008@2|Bacteria,2NNRW@2323|unclassified Bacteria	2|Bacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECIAI39_1322.ECIAI39_0637	tRNA-synt_1c,tRNA-synt_1c_C
FNPCBABE_00288	1121334.KB911067_gene286	1.23e-93	283.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia,3WIP8@541000|Ruminococcaceae	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	fabG5	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
FNPCBABE_00289	1121334.KB911077_gene2436	6.02e-205	583.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WHE3@541000|Ruminococcaceae	186801|Clostridia	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
FNPCBABE_00290	877421.AUJT01000007_gene736	3.24e-65	222.0	COG2182@1|root,COG2182@2|Bacteria,1VRPK@1239|Firmicutes,24Y63@186801|Clostridia,27ISU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
FNPCBABE_00291	1499683.CCFF01000016_gene784	9.07e-173	502.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia,36E1M@31979|Clostridiaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
FNPCBABE_00292	699246.HMPREF0868_0183	2.29e-118	348.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,248A7@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
FNPCBABE_00293	1408416.JNJT01000013_gene455	8.43e-108	340.0	COG0366@1|root,COG0366@2|Bacteria,3WSUF@544448|Tenericutes	544448|Tenericutes	G	alpha-amylase	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
FNPCBABE_00294	428125.CLOLEP_03944	5.61e-87	256.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3WIHG@541000|Ruminococcaceae	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
FNPCBABE_00295	1232443.BAIA02000045_gene2222	1.9e-94	277.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,268CC@186813|unclassified Clostridiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
FNPCBABE_00296	428125.CLOLEP_03946	0.0	1148.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
FNPCBABE_00297	1120746.CCNL01000011_gene1565	2.07e-264	727.0	COG0050@1|root,COG0050@2|Bacteria,2NNQV@2323|unclassified Bacteria	2|Bacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
FNPCBABE_00298	1410632.JHWW01000005_gene745	1.26e-136	392.0	COG1476@1|root,COG1476@2|Bacteria,1UUSK@1239|Firmicutes,247YW@186801|Clostridia,27KQ6@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Zn_ribbon_2
FNPCBABE_00299	428125.CLOLEP_02456	1e-51	169.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,3WJNA@541000|Ruminococcaceae	186801|Clostridia	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
FNPCBABE_00300	1120746.CCNL01000004_gene82	1.08e-134	396.0	COG1104@1|root,COG1104@2|Bacteria	2|Bacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
FNPCBABE_00301	428125.CLOLEP_01204	5.4e-175	500.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,3WGMK@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
FNPCBABE_00302	1120746.CCNL01000004_gene85	5.32e-70	238.0	COG4509@1|root,COG4509@2|Bacteria	2|Bacteria	S	Sortase family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	CinA,MoCF_biosynth,Sortase,SpoIID
FNPCBABE_00304	411473.RUMCAL_01858	5.14e-254	700.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia,3WIMR@541000|Ruminococcaceae	186801|Clostridia	E	Cys Met metabolism	megL	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
FNPCBABE_00306	428125.CLOLEP_03255	1.42e-125	371.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia,3WHG5@541000|Ruminococcaceae	186801|Clostridia	M	Peptidase, M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
FNPCBABE_00307	742738.HMPREF9460_00707	7.78e-172	498.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,268JH@186813|unclassified Clostridiales	186801|Clostridia	M	MBOAT, membrane-bound O-acyltransferase family	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
FNPCBABE_00308	1408437.JNJN01000003_gene1583	4.56e-71	234.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,25WPI@186806|Eubacteriaceae	186801|Clostridia	S	DHHW protein	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
FNPCBABE_00309	1121296.JONJ01000015_gene150	1.27e-36	132.0	COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,24JNB@186801|Clostridia,220HY@1506553|Lachnoclostridium	186801|Clostridia	H	ATP corrinoid adenosyltransferase	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
FNPCBABE_00310	1121334.KB911071_gene2124	3.52e-59	183.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,3WJB6@541000|Ruminococcaceae	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
FNPCBABE_00311	1121334.KB911071_gene2123	2.86e-114	331.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3WHH0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
FNPCBABE_00312	428125.CLOLEP_01035	3.25e-114	331.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
FNPCBABE_00313	411467.BACCAP_02877	6.99e-34	119.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,269KV@186813|unclassified Clostridiales	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
FNPCBABE_00314	428125.CLOLEP_01033	6.52e-168	472.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WGQK@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
FNPCBABE_00315	537013.CLOSTMETH_00184	9.8e-56	174.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3WJ9F@541000|Ruminococcaceae	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
FNPCBABE_00316	428125.CLOLEP_01031	2.1e-53	169.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3WJ9K@541000|Ruminococcaceae	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
FNPCBABE_00317	411473.RUMCAL_00581	6.3e-113	330.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3WGIF@541000|Ruminococcaceae	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
FNPCBABE_00318	428125.CLOLEP_01029	1.13e-86	256.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3WIIZ@541000|Ruminococcaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
FNPCBABE_00319	1121334.KB911071_gene2115	1.12e-21	86.3	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WKVV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
FNPCBABE_00320	97138.C820_00864	6.8e-42	138.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,36KIV@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
FNPCBABE_00321	428125.CLOLEP_01026	4.07e-76	228.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,3WITX@541000|Ruminococcaceae	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
FNPCBABE_00322	428125.CLOLEP_01025	4.2e-59	183.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3WJBH@541000|Ruminococcaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
FNPCBABE_00323	1121334.KB911071_gene2111	6.02e-110	318.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,3WGYQ@541000|Ruminococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
FNPCBABE_00324	1280694.AUJQ01000004_gene453	7.72e-35	119.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,3NHEX@46205|Pseudobutyrivibrio	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
FNPCBABE_00325	428125.CLOLEP_01022	2.44e-75	226.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,3WIYN@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
FNPCBABE_00326	428125.CLOLEP_01021	1.26e-96	284.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,3WIFT@541000|Ruminococcaceae	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
FNPCBABE_00327	1203606.HMPREF1526_02681	2.82e-52	167.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,36JQ0@31979|Clostridiaceae	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
FNPCBABE_00328	1105031.HMPREF1141_0331	1.6e-89	265.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,36DG4@31979|Clostridiaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
FNPCBABE_00329	537013.CLOSTMETH_00170	1.43e-24	92.8	COG1841@1|root,COG1841@2|Bacteria,1UG5U@1239|Firmicutes,24RUS@186801|Clostridia,3WKJT@541000|Ruminococcaceae	186801|Clostridia	J	ribosomal protein	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
FNPCBABE_00330	1121334.KB911071_gene2105	1.39e-65	203.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3WIV7@541000|Ruminococcaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
FNPCBABE_00331	1105031.HMPREF1141_0328	1.71e-208	588.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,36F8Y@31979|Clostridiaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
FNPCBABE_00332	1235835.C814_02981	2.92e-100	296.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3WHQ6@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
FNPCBABE_00333	428125.CLOLEP_01014	1.61e-140	401.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WGEW@541000|Ruminococcaceae	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
FNPCBABE_00334	537013.CLOSTMETH_00165	3.13e-14	68.6	COG2163@1|root,COG2163@2|Bacteria,1VEPA@1239|Firmicutes,24UP0@186801|Clostridia,3WMRS@541000|Ruminococcaceae	186801|Clostridia	J	COG2163 Ribosomal protein L14E L6E L27E	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00335	500635.MITSMUL_05084	1.51e-33	117.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4H53Q@909932|Negativicutes	909932|Negativicutes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
FNPCBABE_00336	999415.HMPREF9943_00576	9.35e-15	66.6	COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,3VSAE@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L36
FNPCBABE_00337	428125.CLOLEP_01010	3.22e-73	220.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3WJ08@541000|Ruminococcaceae	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
FNPCBABE_00338	1120746.CCNL01000017_gene2989	6.28e-70	213.0	COG0100@1|root,COG0100@2|Bacteria,2NPCN@2323|unclassified Bacteria	2|Bacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
FNPCBABE_00339	1519439.JPJG01000018_gene271	2.09e-95	283.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,2N67X@216572|Oscillospiraceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
FNPCBABE_00340	428125.CLOLEP_01007	6.18e-185	519.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WGUM@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
FNPCBABE_00341	428125.CLOLEP_01006	8.13e-56	176.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,3WIRR@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
FNPCBABE_00343	658086.HMPREF0994_01376	1.91e-33	144.0	COG1705@1|root,COG1705@2|Bacteria,1UMKN@1239|Firmicutes,25GKA@186801|Clostridia,27IXC@186928|unclassified Lachnospiraceae	186801|Clostridia	NU	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
FNPCBABE_00344	521460.Athe_1266	5.02e-124	380.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,42F1S@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
FNPCBABE_00345	289377.HL41_01960	3.75e-19	87.0	COG0703@1|root,COG0703@2|Bacteria,2GI06@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
FNPCBABE_00346	665956.HMPREF1032_03995	4.57e-67	213.0	COG1191@1|root,COG1191@2|Bacteria,1V296@1239|Firmicutes,24GTU@186801|Clostridia,3WGPV@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
FNPCBABE_00347	1232443.BAIA02000057_gene1351	1.69e-55	177.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,268UD@186813|unclassified Clostridiales	186801|Clostridia	T	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
FNPCBABE_00348	445972.ANACOL_01712	1.65e-22	91.7	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,3WKRQ@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
FNPCBABE_00349	1121334.KB911066_gene768	1.99e-133	398.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3WGH0@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
FNPCBABE_00350	1120746.CCNL01000017_gene3223	2.74e-130	377.0	COG0313@1|root,COG0313@2|Bacteria,2NP98@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
FNPCBABE_00351	411473.RUMCAL_01800	1.89e-50	172.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,24J47@186801|Clostridia,3WRTS@541000|Ruminococcaceae	186801|Clostridia	S	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	MTS
FNPCBABE_00352	645991.Sgly_0634	5.05e-11	58.5	COG4231@1|root,COG4231@2|Bacteria,1UIUE@1239|Firmicutes,25ES8@186801|Clostridia,267EQ@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
FNPCBABE_00353	428125.CLOLEP_03761	2.8e-148	424.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,3WHA4@541000|Ruminococcaceae	186801|Clostridia	S	PSP1 C-terminal domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
FNPCBABE_00354	1111732.AZOD01000005_gene866	5.88e-05	52.4	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1X34V@135614|Xanthomonadales	135614|Xanthomonadales	L	the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
FNPCBABE_00355	1121423.JONT01000001_gene1864	2.28e-24	99.4	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,262XS@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM phosphodiesterase, MJ0936	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
FNPCBABE_00357	428125.CLOLEP_01049	3.38e-12	66.6	2EH2J@1|root,33AUH@2|Bacteria,1VP6D@1239|Firmicutes,24QT3@186801|Clostridia,3WM9M@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00359	1120746.CCNL01000017_gene3264	9.99e-193	546.0	COG0014@1|root,COG0014@2|Bacteria,2NQM3@2323|unclassified Bacteria	2|Bacteria	E	Aldehyde dehydrogenase family	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iLJ478.TM0293,iYL1228.KPN_00280,iYO844.BSU13130	Aldedh
FNPCBABE_00360	428125.CLOLEP_01053	3.24e-118	345.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,3WGZ7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
FNPCBABE_00361	428125.CLOLEP_02491	2.49e-159	453.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3WGY0@541000|Ruminococcaceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	AA_kinase,HTS
FNPCBABE_00363	592027.CLG_B0490	1.45e-258	719.0	COG0441@1|root,COG0441@2|Bacteria,1UHT4@1239|Firmicutes,25E98@186801|Clostridia,36UJY@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
FNPCBABE_00364	96561.Dole_2083	4.75e-15	70.1	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
FNPCBABE_00365	272563.CD630_05760	9.99e-10	68.6	COG0642@1|root,COG0642@2|Bacteria,1V7G1@1239|Firmicutes,25ER0@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
FNPCBABE_00366	887929.HMP0721_0893	1.09e-77	236.0	COG0350@1|root,COG0350@2|Bacteria,1V2MB@1239|Firmicutes,24HJ0@186801|Clostridia,25W3N@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
FNPCBABE_00368	1298598.JCM21714_4747	5.1e-05	44.3	COG2314@1|root,COG2314@2|Bacteria,1VF2F@1239|Firmicutes,4HP9Y@91061|Bacilli,471ZJ@74385|Gracilibacillus	91061|Bacilli	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
FNPCBABE_00369	411473.RUMCAL_01843	1.05e-304	842.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,3WSPE@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
FNPCBABE_00370	59374.Fisuc_0146	3.02e-199	553.0	COG0175@1|root,COG0175@2|Bacteria	2|Bacteria	EH	sulfate reduction	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
FNPCBABE_00371	411473.RUMCAL_01841	7.27e-48	155.0	COG1146@1|root,COG1146@2|Bacteria,1VADW@1239|Firmicutes,24MQA@186801|Clostridia,3WQFA@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9
FNPCBABE_00372	411473.RUMCAL_01840	3.72e-313	863.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,3WNS7@541000|Ruminococcaceae	186801|Clostridia	C	Fumarate reductase flavoprotein C-term	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
FNPCBABE_00373	1235802.C823_02218	1.14e-107	322.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,25VWS@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
FNPCBABE_00374	411473.RUMCAL_01838	2.91e-76	229.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,3WJ1M@541000|Ruminococcaceae	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
FNPCBABE_00375	1160721.RBI_I01805	1.65e-177	496.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,3WGRI@541000|Ruminococcaceae	186801|Clostridia	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
FNPCBABE_00376	1514668.JOOA01000002_gene1873	1.16e-30	108.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia,3WKGM@541000|Ruminococcaceae	186801|Clostridia	H	TIGRFAM thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
FNPCBABE_00377	411473.RUMCAL_01835	8.64e-41	137.0	COG0526@1|root,COG0526@2|Bacteria,1UG1U@1239|Firmicutes,24SF7@186801|Clostridia,3WKHR@541000|Ruminococcaceae	186801|Clostridia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
FNPCBABE_00378	1160721.RBI_I01808	4.73e-47	151.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia,3WJTK@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
FNPCBABE_00379	1160721.RBI_I01809	1.78e-171	482.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,3WHZF@541000|Ruminococcaceae	186801|Clostridia	C	PFAM nitrite and sulphite reductase 4Fe-4S	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
FNPCBABE_00380	1160721.RBI_I01810	5.75e-226	630.0	COG2873@1|root,COG2873@2|Bacteria,1TXZ1@1239|Firmicutes,248M7@186801|Clostridia,3WH3A@541000|Ruminococcaceae	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
FNPCBABE_00381	1384065.JAGS01000001_gene1529	4.48e-36	129.0	COG1959@1|root,COG1959@2|Bacteria,1V6RP@1239|Firmicutes,24KGB@186801|Clostridia,3WKDJ@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
FNPCBABE_00382	1226325.HMPREF1548_06739	3.85e-199	564.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,36FBX@31979|Clostridiaceae	186801|Clostridia	H	Aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
FNPCBABE_00383	1160721.RBI_I00188	2.92e-169	479.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,3WGUW@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
FNPCBABE_00384	1160721.RBI_I00189	4.2e-159	467.0	COG0007@1|root,COG0007@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,3WHWX@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
FNPCBABE_00385	883156.HMPREF9282_01406	5.87e-54	184.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H1XA@909932|Negativicutes	909932|Negativicutes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
FNPCBABE_00386	1094508.Tsac_1653	9.09e-34	126.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,42GVT@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
FNPCBABE_00387	97139.C824_01556	1.8e-38	149.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,36EQI@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
FNPCBABE_00388	1392491.JIAE01000001_gene1839	1.71e-138	396.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,3WG8S@541000|Ruminococcaceae	186801|Clostridia	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
FNPCBABE_00389	59374.Fisuc_0152	6.46e-179	506.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2,TOBE_3
FNPCBABE_00390	59374.Fisuc_0151	6.11e-147	419.0	COG4208@1|root,COG4208@2|Bacteria	2|Bacteria	P	ATPase-coupled sulfate transmembrane transporter activity	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
FNPCBABE_00391	411473.RUMCAL_00438	5.22e-149	425.0	COG0555@1|root,COG0555@2|Bacteria,1TQHR@1239|Firmicutes,24ACM@186801|Clostridia,3WIAX@541000|Ruminococcaceae	186801|Clostridia	P	Sulfate ABC transporter, permease protein CysT	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
FNPCBABE_00392	411473.RUMCAL_00439	8.68e-190	533.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,24B9S@186801|Clostridia,3WGXR@541000|Ruminococcaceae	186801|Clostridia	P	Extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
FNPCBABE_00393	411470.RUMGNA_03389	2.75e-109	316.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,3XZBD@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	rbr	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubrerythrin
FNPCBABE_00394	500633.CLOHIR_01481	3.01e-184	518.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia,25T34@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
FNPCBABE_00396	411463.EUBVEN_00894	9.62e-186	533.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VAA@186806|Eubacteriaceae	186801|Clostridia	V	CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
FNPCBABE_00397	1121115.AXVN01000001_gene1113	7.98e-96	300.0	COG0038@1|root,COG0038@2|Bacteria,1UZ4F@1239|Firmicutes,24921@186801|Clostridia	186801|Clostridia	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
FNPCBABE_00398	1504822.CCNO01000011_gene176	8.28e-198	561.0	COG0366@1|root,COG0366@2|Bacteria,2NPAG@2323|unclassified Bacteria	2|Bacteria	G	PFAM Alpha amylase, catalytic	malS	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
FNPCBABE_00399	556261.HMPREF0240_01392	6.48e-121	350.0	COG0655@1|root,COG0655@2|Bacteria,1UI36@1239|Firmicutes,247R8@186801|Clostridia,36HCH@31979|Clostridiaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
FNPCBABE_00400	411473.RUMCAL_00791	2.52e-258	712.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae	186801|Clostridia	C	belongs to the iron- containing alcohol dehydrogenase family	adh	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
FNPCBABE_00401	1002367.HMPREF0673_02461	1.17e-18	92.0	COG0583@1|root,COG0583@2|Bacteria,4NJY4@976|Bacteroidetes,2G2WS@200643|Bacteroidia	976|Bacteroidetes	K	LysR substrate binding domain	-	-	-	ko:K11921	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
FNPCBABE_00402	1203606.HMPREF1526_03160	3.46e-170	489.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,36E5Q@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
FNPCBABE_00403	1123405.AUMM01000016_gene2465	4.26e-257	721.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HE02@91061|Bacilli	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
FNPCBABE_00404	994573.T472_0205785	6.53e-27	105.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia,36JT8@31979|Clostridiaceae	186801|Clostridia	S	acyl-CoA thioester hydrolase, YbgC YbaW family	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
FNPCBABE_00405	500632.CLONEX_00518	1.78e-50	163.0	COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,24MNA@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
FNPCBABE_00406	411473.RUMCAL_00859	6.11e-218	610.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,3WGAK@541000|Ruminococcaceae	186801|Clostridia	U	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
FNPCBABE_00407	428125.CLOLEP_03967	1.15e-232	656.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,3WGE5@541000|Ruminococcaceae	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
FNPCBABE_00408	1160721.RBI_II00643	1.28e-218	606.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
FNPCBABE_00409	428125.CLOLEP_00512	5.2e-282	793.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
FNPCBABE_00410	428125.CLOLEP_00513	7.13e-192	544.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3WGWG@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
FNPCBABE_00411	1121334.KB911072_gene2599	1.27e-99	306.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3WGWM@541000|Ruminococcaceae	186801|Clostridia	G	Glucose-1-phosphate adenylyltransferase, GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
FNPCBABE_00412	428125.CLOLEP_00515	8.07e-228	640.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3WGRA@541000|Ruminococcaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
FNPCBABE_00413	1121335.Clst_2135	3.35e-23	98.2	COG3275@1|root,COG3275@2|Bacteria,1VB87@1239|Firmicutes,24UWN@186801|Clostridia,3WKXZ@541000|Ruminococcaceae	186801|Clostridia	T	Pfam:DUF3816	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS,ECF_trnsprt
FNPCBABE_00414	537007.BLAHAN_04528	3.66e-62	200.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,3XZK2@572511|Blautia	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
FNPCBABE_00415	997829.HMPREF1121_00987	1.76e-27	112.0	COG4912@1|root,COG4912@2|Bacteria,4NRBZ@976|Bacteroidetes,2FPS0@200643|Bacteroidia	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
FNPCBABE_00416	997830.HMPREF1124_0933	2.77e-82	256.0	COG3475@1|root,COG3475@2|Bacteria,1TT6A@1239|Firmicutes,4HE2E@91061|Bacilli,43FUW@68892|Streptococcus infantis	91061|Bacilli	M	LicD family	licD3	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
FNPCBABE_00417	195103.CPF_0913	2.34e-100	307.0	COG1215@1|root,COG1215@2|Bacteria,1U4ZW@1239|Firmicutes,25P1E@186801|Clostridia,36EAF@31979|Clostridiaceae	186801|Clostridia	M	Succinoglycan biosynthesis protein exoa	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
FNPCBABE_00419	796606.BMMGA3_13435	3.42e-72	242.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,1ZBI2@1386|Bacillus	91061|Bacilli	E	Dipeptidase	ytjP	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
FNPCBABE_00420	1105031.HMPREF1141_0986	1.71e-241	702.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24C9R@186801|Clostridia,36VYV@31979|Clostridiaceae	186801|Clostridia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
FNPCBABE_00421	1105031.HMPREF1141_0987	3.91e-77	236.0	COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,24FT8@186801|Clostridia,36IZU@31979|Clostridiaceae	186801|Clostridia	S	HD containing hydrolase-like enzyme	yfbR	-	3.1.3.89	ko:K07023,ko:K08722	ko00240,ko01100,map00240,map01100	-	R01569,R01664,R01968,R02088,R02102,R10776	RC00017	ko00000,ko00001,ko01000	-	-	-	HD_2,HD_3
FNPCBABE_00422	641107.CDLVIII_2735	5.04e-36	142.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,36EYW@31979|Clostridiaceae	186801|Clostridia	K	Cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
FNPCBABE_00423	180332.JTGN01000001_gene4588	2.8e-47	172.0	COG1316@1|root,COG1316@2|Bacteria,1UY3P@1239|Firmicutes,24H37@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
FNPCBABE_00424	479437.Elen_1677	1.31e-58	194.0	COG4509@1|root,COG4509@2|Bacteria,2HVXP@201174|Actinobacteria,4CXPZ@84998|Coriobacteriia	84998|Coriobacteriia	S	Sortase family	-	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
FNPCBABE_00426	1514668.JOOA01000002_gene968	1.33e-156	446.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WGEP@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
FNPCBABE_00427	888727.HMPREF9092_1451	4.79e-154	444.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,3WCEM@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
FNPCBABE_00428	1499683.CCFF01000014_gene3594	1.21e-179	551.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,36E5I@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
FNPCBABE_00430	689781.AUJX01000010_gene419	7.26e-89	273.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia,2PRSD@265975|Oribacterium	186801|Clostridia	C	Radical SAM superfamily	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
FNPCBABE_00431	428125.CLOLEP_02682	2.7e-219	627.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,3WG7T@541000|Ruminococcaceae	186801|Clostridia	K	Fibronectin-binding protein	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
FNPCBABE_00432	537013.CLOSTMETH_01536	2.82e-55	178.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,3WIDB@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
FNPCBABE_00433	411473.RUMCAL_02677	3.87e-56	188.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,3WIBU@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
FNPCBABE_00434	428125.CLOLEP_02666	4.3e-201	570.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3WGXG@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
FNPCBABE_00436	246199.CUS_4928	2.31e-108	329.0	COG2954@1|root,COG3911@1|root,COG2954@2|Bacteria,COG3911@2|Bacteria,1TQK3@1239|Firmicutes,24FBY@186801|Clostridia,3WJKT@541000|Ruminococcaceae	186801|Clostridia	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28,CYTH
FNPCBABE_00437	411463.EUBVEN_02379	2.67e-228	630.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,25V2T@186806|Eubacteriaceae	186801|Clostridia	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
FNPCBABE_00438	411460.RUMTOR_01013	1.04e-30	120.0	28RJ8@1|root,2ZDY4@2|Bacteria,1V64R@1239|Firmicutes,24HMT@186801|Clostridia,3Y20R@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00441	875454.BAEW01000007_gene1104	1.72e-06	62.8	COG4932@1|root,COG4932@2|Bacteria,1VMCA@1239|Firmicutes,24DT5@186801|Clostridia,22GXX@1570339|Peptoniphilaceae	186801|Clostridia	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,Gram_pos_anchor,SdrG_C_C
FNPCBABE_00442	622312.ROSEINA2194_02621	4.81e-134	386.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
FNPCBABE_00443	1469948.JPNB01000001_gene2244	3.74e-132	385.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,36EMV@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
FNPCBABE_00444	411471.SUBVAR_05052	8.66e-137	399.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3WHHG@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
FNPCBABE_00445	1120746.CCNL01000011_gene1888	0.0	1446.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
FNPCBABE_00446	394503.Ccel_1904	2.97e-115	349.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,36EU5@31979|Clostridiaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
FNPCBABE_00447	641112.ACOK01000048_gene3892	1.64e-108	325.0	COG0533@1|root,COG0533@2|Bacteria,1TRPY@1239|Firmicutes,24CN4@186801|Clostridia,3WG7R@541000|Ruminococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	gcp1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
FNPCBABE_00448	658086.HMPREF0994_03117	1.39e-22	94.4	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,27NBK@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
FNPCBABE_00449	1121344.JHZO01000004_gene1612	3.88e-08	58.5	2E3US@1|root,32YS3@2|Bacteria	2|Bacteria	S	Stage III sporulation protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
FNPCBABE_00450	1232452.BAIB02000005_gene883	2.7e-11	65.5	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia,26CBE@186813|unclassified Clostridiales	186801|Clostridia	S	Stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
FNPCBABE_00452	1120746.CCNL01000011_gene1594	2.28e-56	196.0	2C2CG@1|root,2Z7PW@2|Bacteria	2|Bacteria	S	stage III sporulation protein AE	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
FNPCBABE_00453	537013.CLOSTMETH_02786	6.87e-19	83.6	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AD	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
FNPCBABE_00454	509191.AEDB02000109_gene5020	7.04e-19	79.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,3WKGF@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
FNPCBABE_00456	428125.CLOLEP_03176	1.65e-82	259.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,3WGH3@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
FNPCBABE_00458	428125.CLOLEP_03177	5.24e-296	828.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WGTP@541000|Ruminococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
FNPCBABE_00459	428125.CLOLEP_00564	4.05e-99	291.0	COG3481@1|root,COG3481@2|Bacteria,1TQEK@1239|Firmicutes,24BRR@186801|Clostridia,3WIKZ@541000|Ruminococcaceae	186801|Clostridia	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
FNPCBABE_00461	246199.CUS_7776	4.84e-133	392.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,3WGN5@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
FNPCBABE_00462	1410670.JHXF01000021_gene2399	7.22e-44	150.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3WIX8@541000|Ruminococcaceae	186801|Clostridia	J	Sigma 54 modulation/S30EA ribosomal protein C terminus	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
FNPCBABE_00463	1235835.C814_00754	4.16e-37	132.0	COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,24MPT@186801|Clostridia,3WJUX@541000|Ruminococcaceae	186801|Clostridia	J	S1 RNA binding domain	yugI	-	-	ko:K07570,ko:K07571	-	-	-	-	ko00000	-	-	-	S1
FNPCBABE_00464	663278.Ethha_0352	8.82e-10	59.7	COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,24WD9@186801|Clostridia,3WMB8@541000|Ruminococcaceae	186801|Clostridia	D	Septum formation initiator	-	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
FNPCBABE_00465	428125.CLOLEP_03271	5.45e-19	81.3	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia,3WKKJ@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YabP	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
FNPCBABE_00466	1282887.AUJG01000003_gene536	3.82e-32	113.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
FNPCBABE_00467	500635.MITSMUL_04770	1.19e-31	113.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4H539@909932|Negativicutes	909932|Negativicutes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
FNPCBABE_00468	1121334.KB911066_gene924	8.17e-101	302.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,3WHY1@541000|Ruminococcaceae	186801|Clostridia	S	MazG family	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
FNPCBABE_00469	1232666.JANE01000034_gene1675	8.1e-15	86.3	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,4GXVB@90964|Staphylococcaceae	91061|Bacilli	S	Polysaccharide biosynthesis protein	ytgP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_C
FNPCBABE_00471	428125.CLOLEP_03103	2.16e-179	518.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,3WGA8@541000|Ruminococcaceae	186801|Clostridia	C	Coproporphyrinogen dehydrogenase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
FNPCBABE_00472	1235835.C814_01424	1.25e-48	165.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,3WHAR@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
FNPCBABE_00473	1160721.RBI_II00337	1.12e-55	178.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3WJM2@541000|Ruminococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
FNPCBABE_00474	428125.CLOLEP_03100	0.0	891.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,3WGUK@541000|Ruminococcaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
FNPCBABE_00475	428125.CLOLEP_03099	3.01e-233	672.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3WI09@541000|Ruminococcaceae	186801|Clostridia	L	exonuclease	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
FNPCBABE_00476	428125.CLOLEP_03158	4.85e-156	464.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3WHDP@541000|Ruminococcaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
FNPCBABE_00477	1230342.CTM_12810	5.69e-40	138.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,36IRA@31979|Clostridiaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
FNPCBABE_00478	1304888.ATWF01000001_gene1156	1.26e-44	159.0	COG0061@1|root,COG0061@2|Bacteria,2GEK1@200930|Deferribacteres	200930|Deferribacteres	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
FNPCBABE_00479	1121334.KB911066_gene622	1.18e-124	362.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3WGGG@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
FNPCBABE_00480	1410670.JHXF01000010_gene442	1.16e-208	604.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3WGVF@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
FNPCBABE_00481	537013.CLOSTMETH_02773	2.22e-83	259.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,3WINP@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
FNPCBABE_00482	545264.KB898746_gene691	3.66e-05	45.4	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
FNPCBABE_00483	641112.ACOK01000097_gene901	8.11e-63	208.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,3WHUA@541000|Ruminococcaceae	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
FNPCBABE_00484	411471.SUBVAR_05034	3.2e-94	286.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,3WGDD@541000|Ruminococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
FNPCBABE_00485	428125.CLOLEP_00067	1.51e-103	311.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3WGX6@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
FNPCBABE_00486	1105031.HMPREF1141_2476	2.77e-141	409.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,36F8F@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
FNPCBABE_00489	428125.CLOLEP_01990	1.8e-176	512.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,3WHDF@541000|Ruminococcaceae	186801|Clostridia	EG	spore germination protein	-	-	-	ko:K06295	-	-	-	-	ko00000	-	-	-	GerA
FNPCBABE_00490	1105031.HMPREF1141_1524	2.59e-60	194.0	COG2323@1|root,COG2323@2|Bacteria,1V3NW@1239|Firmicutes,24H1Q@186801|Clostridia,36DZ1@31979|Clostridiaceae	186801|Clostridia	K	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
FNPCBABE_00492	903814.ELI_0567	3.39e-108	321.0	COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,24875@186801|Clostridia,25V63@186806|Eubacteriaceae	186801|Clostridia	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
FNPCBABE_00493	1280696.ATVY01000006_gene865	4.5e-86	264.0	COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,248F1@186801|Clostridia,4BWZ2@830|Butyrivibrio	186801|Clostridia	P	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
FNPCBABE_00494	1292035.H476_2990	5.01e-92	285.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,25R39@186804|Peptostreptococcaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
FNPCBABE_00495	428125.CLOLEP_02702	1.03e-104	317.0	COG0341@1|root,COG0341@2|Bacteria,1TSZE@1239|Firmicutes,249A3@186801|Clostridia,3WGWX@541000|Ruminococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
FNPCBABE_00496	877411.JMMA01000002_gene2315	5.67e-138	422.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,3WGN7@541000|Ruminococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
FNPCBABE_00497	1120746.CCNL01000011_gene1841	6.25e-196	555.0	COG1167@1|root,COG1167@2|Bacteria	2|Bacteria	K	transaminase activity	aspT	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
FNPCBABE_00498	525378.HMPREF0793_0770	1.83e-37	138.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,4GXUA@90964|Staphylococcaceae	91061|Bacilli	D	ATPase MipZ	capB	-	-	-	-	-	-	-	-	-	-	-	AAA_31
FNPCBABE_00499	333138.LQ50_22235	2.94e-12	72.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,1ZBJ4@1386|Bacillus	91061|Bacilli	M	biosynthesis protein	ywqC	-	-	ko:K19420	-	-	-	-	ko00000	-	-	-	GNVR,Wzz
FNPCBABE_00500	1120746.CCNL01000010_gene1410	2.93e-199	562.0	COG1883@1|root,COG1883@2|Bacteria,2NP19@2323|unclassified Bacteria	2|Bacteria	C	Na+-transporting oxaloacetate decarboxylase beta subunit	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
FNPCBABE_00502	428125.CLOLEP_02350	3.06e-245	686.0	COG5019@1|root,COG5019@2|Bacteria,1UHVS@1239|Firmicutes,25E4Q@186801|Clostridia,3WGJE@541000|Ruminococcaceae	186801|Clostridia	DZ	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	-	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
FNPCBABE_00503	1105031.HMPREF1141_3016	6.63e-104	327.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,36EW2@31979|Clostridiaceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
FNPCBABE_00505	1121334.KB911066_gene526	1.08e-140	407.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,3WH5D@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
FNPCBABE_00506	428125.CLOLEP_01578	1.8e-112	332.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,3WHV2@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
FNPCBABE_00508	246199.CUS_5738	4.83e-83	249.0	COG0221@1|root,COG0221@2|Bacteria,1V2DF@1239|Firmicutes,24G1A@186801|Clostridia,3WI3Y@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
FNPCBABE_00509	428125.CLOLEP_03693	6.24e-134	387.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,3WGJ1@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
FNPCBABE_00510	1160721.RBI_I01220	2.8e-176	511.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,3WGEV@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
FNPCBABE_00511	478749.BRYFOR_08918	7.42e-19	78.6	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia	186801|Clostridia	S	COG NOG17973 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
FNPCBABE_00514	457396.CSBG_03069	1.23e-115	350.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,36FR4@31979|Clostridiaceae	186801|Clostridia	P	Chloride channel	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
FNPCBABE_00515	411489.CLOL250_02376	6.15e-170	481.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,36EYX@31979|Clostridiaceae	186801|Clostridia	M	Choloylglycine hydrolase	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
FNPCBABE_00517	411469.EUBHAL_01061	5.75e-213	596.0	COG0786@1|root,COG0786@2|Bacteria,1TQA4@1239|Firmicutes,247WX@186801|Clostridia,25V8Y@186806|Eubacteriaceae	186801|Clostridia	P	Catalyzes the sodium-dependent transport of glutamate	gltS	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter,NMT1_3
FNPCBABE_00518	748224.HMPREF9436_02554	5.49e-85	266.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,3WIYW@541000|Ruminococcaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
FNPCBABE_00519	428125.CLOLEP_02204	1.6e-155	449.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
FNPCBABE_00521	428125.CLOLEP_02201	5.65e-182	520.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3WG8Y@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA2	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
FNPCBABE_00522	428125.CLOLEP_02200	7.77e-177	503.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,3WGFH@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
FNPCBABE_00523	1121334.KB911066_gene756	4.98e-124	372.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WHWW@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
FNPCBABE_00524	428125.CLOLEP_02197	2.22e-123	365.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3WHMP@541000|Ruminococcaceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
FNPCBABE_00525	1121334.KB911066_gene759	2.17e-227	661.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WGI4@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
FNPCBABE_00527	1120746.CCNL01000010_gene1107	1.92e-132	385.0	COG0275@1|root,COG0275@2|Bacteria,2NP8Y@2323|unclassified Bacteria	2|Bacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
FNPCBABE_00528	1105031.HMPREF1141_1547	3.29e-28	109.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,36I1C@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
FNPCBABE_00530	1120746.CCNL01000010_gene1105	3.1e-32	119.0	COG0711@1|root,COG0711@2|Bacteria	2|Bacteria	C	ATP synthesis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00531	445972.ANACOL_00440	1.83e-61	194.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,3WJBF@541000|Ruminococcaceae	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
FNPCBABE_00532	428125.CLOLEP_02183	6.67e-69	215.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3WJC4@541000|Ruminococcaceae	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
FNPCBABE_00533	1120746.CCNL01000010_gene1102	2.89e-270	759.0	COG0322@1|root,COG0322@2|Bacteria,2NNQ4@2323|unclassified Bacteria	2|Bacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	DUF4837,GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
FNPCBABE_00534	537013.CLOSTMETH_02429	8.8e-48	153.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,3WK5I@541000|Ruminococcaceae	186801|Clostridia	G	phosphocarrier, HPr family	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
FNPCBABE_00535	428125.CLOLEP_02178	2.86e-125	361.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,3WH8Z@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
FNPCBABE_00536	411473.RUMCAL_01279	3.16e-59	189.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,3WIMH@541000|Ruminococcaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
FNPCBABE_00537	1105031.HMPREF1141_0222	6.36e-299	847.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,36EFY@31979|Clostridiaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
FNPCBABE_00538	1120746.CCNL01000010_gene1088	9.29e-81	250.0	COG1381@1|root,COG1381@2|Bacteria	2|Bacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
FNPCBABE_00540	428125.CLOLEP_02165	7e-148	424.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,3WGJ2@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
FNPCBABE_00541	1121423.JONT01000001_gene1980	1.48e-11	65.5	COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,248FD@186801|Clostridia,262TJ@186807|Peptococcaceae	186801|Clostridia	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar,PAP2
FNPCBABE_00542	1121334.KB911069_gene1749	1.67e-82	248.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,3WIDY@541000|Ruminococcaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
FNPCBABE_00543	1105031.HMPREF1141_0230	2.23e-182	514.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,36UI2@31979|Clostridiaceae	186801|Clostridia	T	PhoH-like protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
FNPCBABE_00544	1121334.KB911069_gene1756	6.65e-27	103.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,3WKPX@541000|Ruminococcaceae	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
FNPCBABE_00545	428125.CLOLEP_02173	3.97e-219	617.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3WH5J@541000|Ruminococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
FNPCBABE_00546	649747.HMPREF0083_02695	7.97e-32	113.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,26Y76@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
FNPCBABE_00547	1121334.KB911069_gene1759	2.52e-29	106.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,3WKWP@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
FNPCBABE_00548	411467.BACCAP_01285	1.33e-258	716.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,258AH@186801|Clostridia,26BAA@186813|unclassified Clostridiales	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
FNPCBABE_00550	1121334.KB911069_gene1714	0.0	1073.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WGYI@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
FNPCBABE_00551	1449063.JMLS01000035_gene6327	8.33e-92	285.0	COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,4HC6U@91061|Bacilli,26T89@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
FNPCBABE_00552	1382305.AZUC01000007_gene1475	3.06e-13	71.6	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HNM5@91061|Bacilli,26ICG@186818|Planococcaceae	91061|Bacilli	S	UvrB/uvrC motif	-	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
FNPCBABE_00553	1507.HMPREF0262_00628	1.6e-51	167.0	COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,24JH3@186801|Clostridia,36JKR@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the CtsR family	ctsR	-	-	ko:K03708	-	-	-	-	ko00000,ko03000	-	-	-	CtsR
FNPCBABE_00560	1410617.JHXH01000018_gene1171	1.52e-46	150.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
FNPCBABE_00561	861450.HMPREF0080_01893	2.29e-25	105.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,4H2TH@909932|Negativicutes	909932|Negativicutes	K	Belongs to the sigma-70 factor family	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
FNPCBABE_00562	428125.CLOLEP_02672	4.36e-212	603.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,3WH36@541000|Ruminococcaceae	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
FNPCBABE_00563	411473.RUMCAL_01098	2.27e-25	95.5	COG1251@1|root,COG1251@2|Bacteria,1W1DD@1239|Firmicutes,25EHF@186801|Clostridia,3WSM6@541000|Ruminococcaceae	186801|Clostridia	C	Hydrid cluster protein-associated redox disulfide domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
FNPCBABE_00564	1105031.HMPREF1141_2696	1.81e-41	147.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,36FNA@31979|Clostridiaceae	186801|Clostridia	S	SAM-dependent methyltransferase	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
FNPCBABE_00565	411473.RUMCAL_01095	4.08e-34	130.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,3WJ9H@541000|Ruminococcaceae	186801|Clostridia	S	dinuclear metal center protein, YbgI	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
FNPCBABE_00566	1514668.JOOA01000002_gene3410	3.43e-84	256.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia,3WIGB@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
FNPCBABE_00567	428125.CLOLEP_01976	9.96e-37	147.0	COG0457@1|root,COG0457@2|Bacteria,1V0WM@1239|Firmicutes,24D57@186801|Clostridia,3WS6H@541000|Ruminococcaceae	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
FNPCBABE_00568	428125.CLOLEP_01977	4.45e-139	396.0	COG0745@1|root,COG0745@2|Bacteria,1TPN8@1239|Firmicutes,248UA@186801|Clostridia,3WGQR@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
FNPCBABE_00569	1232443.BAIA02000041_gene2123	3.34e-118	361.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,2689S@186813|unclassified Clostridiales	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
FNPCBABE_00570	1120746.CCNL01000017_gene3067	2.87e-125	368.0	COG3872@1|root,COG3872@2|Bacteria,2NP59@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1385)	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385
FNPCBABE_00571	697329.Rumal_2214	3.93e-69	222.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,3WGK1@541000|Ruminococcaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
FNPCBABE_00572	428125.CLOLEP_01982	2e-197	556.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3WGST@541000|Ruminococcaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
FNPCBABE_00573	428125.CLOLEP_01983	2.78e-68	214.0	COG2137@1|root,COG2137@2|Bacteria,1VAFI@1239|Firmicutes,25DPI@186801|Clostridia,3WSGY@541000|Ruminococcaceae	186801|Clostridia	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
FNPCBABE_00574	1160721.RBI_II00118	3.5e-189	540.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,3WH46@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
FNPCBABE_00575	1423815.BACR01000014_gene910	8.43e-38	136.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,3F4BI@33958|Lactobacillaceae	91061|Bacilli	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06365	CDP-OH_P_transf
FNPCBABE_00576	428125.CLOLEP_01986	1.59e-96	287.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,3WHD9@541000|Ruminococcaceae	186801|Clostridia	E	serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
FNPCBABE_00577	411467.BACCAP_02437	1.57e-254	707.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,2684B@186813|unclassified Clostridiales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
FNPCBABE_00578	180332.JTGN01000011_gene571	1.05e-73	233.0	COG0726@1|root,COG0726@2|Bacteria,1UZGG@1239|Firmicutes,249C9@186801|Clostridia	186801|Clostridia	G	Polysaccharide deacetylase	pdaB	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
FNPCBABE_00579	471875.RUMLAC_01562	0.0	1241.0	COG1470@1|root,COG2247@1|root,COG3210@1|root,COG4733@1|root,COG1470@2|Bacteria,COG2247@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,1UVKS@1239|Firmicutes,257XV@186801|Clostridia,3WK9A@541000|Ruminococcaceae	186801|Clostridia	U	COG COG3210 Large exoproteins involved in heme utilization or adhesion	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
FNPCBABE_00580	394503.Ccel_0471	1.56e-66	225.0	COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,248J8@186801|Clostridia,36G8B@31979|Clostridiaceae	186801|Clostridia	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
FNPCBABE_00581	1120746.CCNL01000011_gene1765	4.6e-171	493.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	ymfH	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
FNPCBABE_00582	428125.CLOLEP_02649	6.33e-145	415.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3WGHP@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
FNPCBABE_00583	931276.Cspa_c51980	5.26e-31	112.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,36JGP@31979|Clostridiaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
FNPCBABE_00584	428125.CLOLEP_02655	4.07e-27	102.0	COG2868@1|root,COG2868@2|Bacteria,1VKWQ@1239|Firmicutes,24TYG@186801|Clostridia,3WJZE@541000|Ruminococcaceae	186801|Clostridia	J	Cysteine protease Prp	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
FNPCBABE_00585	1280689.AUJC01000001_gene2246	1.83e-51	163.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,36JKM@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
FNPCBABE_00586	428125.CLOLEP_02657	7.27e-233	649.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3WH1H@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
FNPCBABE_00587	397290.C810_01780	4.58e-31	115.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,27NXY@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
FNPCBABE_00588	537013.CLOSTMETH_02817	3.14e-74	236.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,249DE@186801|Clostridia,3WSC6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
FNPCBABE_00589	1410624.JNKK01000002_gene895	6.14e-58	200.0	COG0463@1|root,COG0463@2|Bacteria,1TQ8C@1239|Firmicutes,248MK@186801|Clostridia,27KKC@186928|unclassified Lachnospiraceae	186801|Clostridia	M	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
FNPCBABE_00590	511680.BUTYVIB_01595	4.46e-192	562.0	COG0366@1|root,COG0366@2|Bacteria,1TQSE@1239|Firmicutes,24C4V@186801|Clostridia,4BWVW@830|Butyrivibrio	186801|Clostridia	G	Starch-binding module 26	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Big_2,CBM26,CW_binding_1,Y_Y_Y
FNPCBABE_00592	1693.BMIN_1092	4.4e-60	228.0	COG0366@1|root,COG5492@1|root,COG0366@2|Bacteria,COG5492@2|Bacteria,2GM4Q@201174|Actinobacteria,4CYYI@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM26,CBM_25,SLH
FNPCBABE_00593	1120746.CCNL01000011_gene1679	1.36e-128	371.0	COG0107@1|root,COG0107@2|Bacteria,2NNMK@2323|unclassified Bacteria	2|Bacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
FNPCBABE_00594	428125.CLOLEP_03235	1.17e-96	286.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,3WGIA@541000|Ruminococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
FNPCBABE_00595	428125.CLOLEP_03186	3.16e-127	370.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia,3WGRZ@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
FNPCBABE_00596	1120746.CCNL01000011_gene1579	6.26e-173	496.0	COG2081@1|root,COG2081@2|Bacteria,2NPCB@2323|unclassified Bacteria	2|Bacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
FNPCBABE_00597	478749.BRYFOR_09888	1.89e-65	208.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
FNPCBABE_00598	883114.HMPREF9709_00773	5.07e-21	93.6	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,25B02@186801|Clostridia,22HER@1570339|Peptoniphilaceae	186801|Clostridia	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
FNPCBABE_00599	1120746.CCNL01000011_gene1583	5.87e-276	777.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	ispH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.4,2.7.4.25	ko:K00945,ko:K02945,ko:K03527	ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010	M00052,M00096,M00178	R00158,R00512,R01665,R05884,R08210	RC00002,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	iECIAI1_1343.ECIAI1_0030,iECW_1372.ECW_m0028,iEKO11_1354.EKO11_3884,iEcHS_1320.EcHS_A0031,iEcolC_1368.EcolC_3626,iIT341.HP0400,iLJ478.TM1444,iPC815.YPO0477,iSFV_1184.SFV_0023,iSF_1195.SF0026,iSFxv_1172.SFxv_0027,iS_1188.S0028,iWFL_1372.ECW_m0028,iYL1228.KPN_00024	LYTB,S1
FNPCBABE_00601	428125.CLOLEP_02910	2.12e-129	372.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3WHDN@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
FNPCBABE_00602	1120746.CCNL01000011_gene1698	9.69e-120	352.0	COG1561@1|root,COG1561@2|Bacteria,2NPG5@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1732)	yicC	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	DUF1732,YicC_N
FNPCBABE_00603	1514668.JOOA01000002_gene2086	1.14e-24	95.1	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,3WJWB@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
FNPCBABE_00604	1229172.JQFA01000004_gene1565	2.45e-50	168.0	COG0194@1|root,COG0194@2|Bacteria,1G515@1117|Cyanobacteria,1HAKW@1150|Oscillatoriales	1117|Cyanobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
FNPCBABE_00606	428125.CLOLEP_02337	0.0	915.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3WGTG@541000|Ruminococcaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
FNPCBABE_00607	1507.HMPREF0262_02227	1.56e-60	191.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,36IPZ@31979|Clostridiaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
FNPCBABE_00608	883156.HMPREF9282_01919	2.85e-95	291.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4H2M2@909932|Negativicutes	909932|Negativicutes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
FNPCBABE_00609	1203606.HMPREF1526_00451	5.27e-74	231.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,36FA7@31979|Clostridiaceae	186801|Clostridia	S	zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
FNPCBABE_00610	1304284.L21TH_0671	1.3e-108	335.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,36DEN@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
FNPCBABE_00611	428125.CLOLEP_02342	4.86e-153	441.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3WGYF@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
FNPCBABE_00612	1380390.JIAT01000009_gene1779	6.87e-41	152.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
FNPCBABE_00613	1121334.KB911066_gene645	2.57e-219	635.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WGK8@541000|Ruminococcaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
FNPCBABE_00614	428125.CLOLEP_02345	2.09e-109	326.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,3WGGY@541000|Ruminococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
FNPCBABE_00615	1291050.JAGE01000002_gene3742	8.17e-24	101.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3WJUT@541000|Ruminococcaceae	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
FNPCBABE_00617	1120746.CCNL01000014_gene2042	2.35e-105	334.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria	2|Bacteria	G	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,TIR_2
FNPCBABE_00618	537013.CLOSTMETH_00658	6.1e-40	134.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3WJT1@541000|Ruminococcaceae	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
FNPCBABE_00619	428125.CLOLEP_02071	1.32e-297	823.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3WGUG@541000|Ruminococcaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
FNPCBABE_00620	658088.HMPREF0987_00084	4.93e-20	83.6	2E5V7@1|root,330JA@2|Bacteria,1VFNT@1239|Firmicutes,24RD2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
FNPCBABE_00621	665950.HMPREF1025_02156	1.52e-23	97.1	COG0681@1|root,COG0681@2|Bacteria,1VFKY@1239|Firmicutes,24RQG@186801|Clostridia,27SM3@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
FNPCBABE_00622	485916.Dtox_2894	6.61e-56	196.0	28NW3@1|root,2ZBU0@2|Bacteria,1V2IM@1239|Firmicutes,24GA1@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
FNPCBABE_00623	521003.COLINT_02710	3.75e-36	138.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4CVJC@84998|Coriobacteriia	84998|Coriobacteriia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
FNPCBABE_00624	1280673.AUJJ01000009_gene2990	1.75e-33	142.0	2A1D0@1|root,30PK1@2|Bacteria,1UKEI@1239|Firmicutes,25G46@186801|Clostridia,4C2AI@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00625	357809.Cphy_3205	1.07e-130	382.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,21Z7T@1506553|Lachnoclostridium	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
FNPCBABE_00626	1121334.KB911074_gene2538	7.86e-30	109.0	COG3906@1|root,COG3906@2|Bacteria,1VF5Z@1239|Firmicutes,24V04@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0473 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
FNPCBABE_00627	411459.RUMOBE_02905	6.4e-79	243.0	COG2148@1|root,COG2148@2|Bacteria,1TP7V@1239|Firmicutes,25AZD@186801|Clostridia,3Y00N@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
FNPCBABE_00628	428125.CLOLEP_01530	1.71e-50	187.0	COG3307@1|root,COG3307@2|Bacteria,1VK2G@1239|Firmicutes,24S8D@186801|Clostridia	186801|Clostridia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
FNPCBABE_00629	641112.ACOK01000112_gene2108	1.99e-283	795.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,3WH2R@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
FNPCBABE_00631	1444309.JAQG01000172_gene446	1.84e-36	130.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,4HH9K@91061|Bacilli,26RX2@186822|Paenibacillaceae	91061|Bacilli	K	AsnC family transcriptional regulator	alaR	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
FNPCBABE_00632	428125.CLOLEP_03309	8.95e-210	588.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WGAJ@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
FNPCBABE_00633	521460.Athe_1538	1.57e-54	185.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,42GD3@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
FNPCBABE_00634	411460.RUMTOR_02734	8.27e-36	132.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,24J91@186801|Clostridia,3Y092@572511|Blautia	186801|Clostridia	S	Stage II sporulation protein R (spore_II_R)	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
FNPCBABE_00635	428125.CLOLEP_00237	1.63e-250	706.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3WGEY@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
FNPCBABE_00636	500632.CLONEX_00165	2.04e-103	333.0	COG3274@1|root,COG3274@2|Bacteria,1UYCP@1239|Firmicutes,24FH8@186801|Clostridia	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
FNPCBABE_00637	1536774.H70357_00975	1.25e-15	88.2	COG1807@1|root,COG1807@2|Bacteria,1V6SZ@1239|Firmicutes,4HRSD@91061|Bacilli,276RN@186822|Paenibacillaceae	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
FNPCBABE_00638	1280673.AUJJ01000011_gene1980	5.71e-145	418.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,4BYPC@830|Butyrivibrio	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
FNPCBABE_00639	428125.CLOLEP_00557	2.08e-165	471.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3WH67@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
FNPCBABE_00641	1120746.CCNL01000010_gene1198	1.01e-53	182.0	COG0668@1|root,COG0668@2|Bacteria,2NP91@2323|unclassified Bacteria	2|Bacteria	M	Mechanosensitive ion channel	mscS	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022607,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055082,GO:0055085,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
FNPCBABE_00644	428125.CLOLEP_02097	1.29e-109	321.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,3WGM5@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
FNPCBABE_00645	1120746.CCNL01000011_gene1798	8.69e-41	149.0	2APHB@1|root,31EKA@2|Bacteria,2NRSM@2323|unclassified Bacteria	2|Bacteria	S	Sporulation factor SpoIIGA	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U4
FNPCBABE_00646	318464.IO99_15925	1.2e-98	298.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,36EZJ@31979|Clostridiaceae	186801|Clostridia	S	DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
FNPCBABE_00647	663278.Ethha_1626	1.34e-16	75.5	COG1873@1|root,COG1873@2|Bacteria,1VGWH@1239|Firmicutes,259AU@186801|Clostridia,3WKPN@541000|Ruminococcaceae	186801|Clostridia	S	sporulation protein, YlmC YmxH family	-	-	-	-	-	-	-	-	-	-	-	-	PRC
FNPCBABE_00649	428125.CLOLEP_02104	1.51e-144	410.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
FNPCBABE_00650	428125.CLOLEP_02105	2.26e-141	408.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
FNPCBABE_00651	428125.CLOLEP_03303	9.04e-97	285.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,3WIZW@541000|Ruminococcaceae	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
FNPCBABE_00652	428125.CLOLEP_03302	5.89e-34	117.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,3WKKQ@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
FNPCBABE_00653	428125.CLOLEP_03301	3.15e-66	202.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,3WIYY@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
FNPCBABE_00654	428125.CLOLEP_03300	7.88e-84	258.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,3WIQ9@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
FNPCBABE_00655	935948.KE386494_gene301	2.14e-43	162.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,42FQZ@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
FNPCBABE_00656	428125.CLOLEP_03298	0.0	927.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,3WGDZ@541000|Ruminococcaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
FNPCBABE_00657	1120746.CCNL01000012_gene1942	1.29e-211	596.0	COG1206@1|root,COG1206@2|Bacteria,2NS4B@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
FNPCBABE_00658	1105031.HMPREF1141_2669	1.27e-133	390.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,36E96@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
FNPCBABE_00659	428125.CLOLEP_03295	8.05e-108	317.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3WG7D@541000|Ruminococcaceae	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
FNPCBABE_00660	246199.CUS_7441	4.21e-90	281.0	COG1243@1|root,COG1243@2|Bacteria,1TS1F@1239|Firmicutes,248YV@186801|Clostridia,3WGUJ@541000|Ruminococcaceae	186801|Clostridia	BK	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,Radical_SAM_C
FNPCBABE_00661	1120746.CCNL01000012_gene1938	0.0	959.0	COG1196@1|root,COG1196@2|Bacteria,2NNYZ@2323|unclassified Bacteria	2|Bacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
FNPCBABE_00662	428125.CLOLEP_03292	2.48e-157	448.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3WGFT@541000|Ruminococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
FNPCBABE_00663	1514668.JOOA01000002_gene3188	1.49e-62	199.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,3WIUM@541000|Ruminococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
FNPCBABE_00664	1410670.JHXF01000009_gene296	4.68e-33	117.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,3WKIM@541000|Ruminococcaceae	186801|Clostridia	J	RNA-binding protein, YhbY family	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
FNPCBABE_00665	338963.Pcar_2578	7.74e-31	119.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria,43TRZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Cytidylyltransferase-like	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
FNPCBABE_00666	235909.GK2521	5.14e-39	139.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,1WFI5@129337|Geobacillus	91061|Bacilli	H	Metal dependent phosphohydrolases with conserved 'HD' motif.	yqeK	-	-	-	-	-	-	-	-	-	-	-	HD
FNPCBABE_00667	1105031.HMPREF1141_2678	1.31e-38	132.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,36KHS@31979|Clostridiaceae	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
FNPCBABE_00668	1120746.CCNL01000012_gene1931	0.0	1351.0	COG0495@1|root,COG0495@2|Bacteria,2NNQH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
FNPCBABE_00669	720554.Clocl_2790	1.03e-22	88.2	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,3WKHJ@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
FNPCBABE_00670	1120746.CCNL01000011_gene1643	2.91e-75	227.0	COG0757@1|root,COG0757@2|Bacteria,2NPMW@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0349	DHquinase_II
FNPCBABE_00671	697284.ERIC2_c33050	1.1e-84	268.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,26QP9@186822|Paenibacillaceae	91061|Bacilli	E	Xaa-Pro dipeptidase	yqhT	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
FNPCBABE_00672	1105031.HMPREF1141_0768	8.22e-120	343.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,36DS4@31979|Clostridiaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
FNPCBABE_00673	1105031.HMPREF1141_0769	4.91e-28	108.0	2E3FE@1|root,32YE8@2|Bacteria,1VFR0@1239|Firmicutes,24MNV@186801|Clostridia,36W39@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00674	537013.CLOSTMETH_02581	1.42e-23	101.0	2B51H@1|root,31XUS@2|Bacteria,1V6KA@1239|Firmicutes,24JQP@186801|Clostridia,3WKHP@541000|Ruminococcaceae	186801|Clostridia	S	sporulation protein YunB	yunB	-	-	-	-	-	-	-	-	-	-	-	Spore_YunB
FNPCBABE_00675	1120746.CCNL01000011_gene1865	1.63e-231	649.0	COG0621@1|root,COG0621@2|Bacteria,2NNUN@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
FNPCBABE_00676	1121334.KB911070_gene1301	3.54e-27	105.0	COG3679@1|root,COG3679@2|Bacteria,1VDFJ@1239|Firmicutes,24MY6@186801|Clostridia,3WJJP@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0342 family	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
FNPCBABE_00677	428125.CLOLEP_01950	0.0	1086.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WGM4@541000|Ruminococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
FNPCBABE_00678	1105031.HMPREF1141_2196	1.25e-217	632.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,36EVN@31979|Clostridiaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
FNPCBABE_00679	537013.CLOSTMETH_02461	6.53e-99	301.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3WGGD@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
FNPCBABE_00680	1121334.KB911070_gene1297	3.29e-62	214.0	COG0845@1|root,COG0845@2|Bacteria,1V9GB@1239|Firmicutes,24HX2@186801|Clostridia,3WJMC@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00681	428125.CLOLEP_01955	4.81e-92	278.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3WGKD@541000|Ruminococcaceae	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
FNPCBABE_00682	1105031.HMPREF1141_2200	2.35e-62	196.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,36I3V@31979|Clostridiaceae	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
FNPCBABE_00683	386415.NT01CX_1947	3.1e-26	110.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,36IWC@31979|Clostridiaceae	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
FNPCBABE_00684	411471.SUBVAR_05058	2.38e-21	97.4	COG3599@1|root,COG3599@2|Bacteria,1VGCY@1239|Firmicutes,24TVY@186801|Clostridia,3WM0J@541000|Ruminococcaceae	186801|Clostridia	D	DivIVA domain protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
FNPCBABE_00685	428125.CLOLEP_01959	0.0	1390.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3WG9B@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
FNPCBABE_00686	644966.Tmar_0892	8.96e-27	107.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3WDCK@538999|Clostridiales incertae sedis	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
FNPCBABE_00687	1121334.KB911070_gene1291	1.41e-125	368.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,3WGKV@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
FNPCBABE_00688	428125.CLOLEP_02366	4.03e-59	184.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,3WJ8U@541000|Ruminococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
FNPCBABE_00689	1410670.JHXF01000010_gene542	1.19e-30	120.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24MVR@186801|Clostridia,3WSDM@541000|Ruminococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
FNPCBABE_00690	1105031.HMPREF1141_2304	9.02e-18	74.7	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,36P8G@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
FNPCBABE_00691	485916.Dtox_4369	1.57e-11	63.5	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,262VE@186807|Peptococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
FNPCBABE_00692	996637.SGM_3529	6.83e-26	99.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
FNPCBABE_00693	622312.ROSEINA2194_02514	9.01e-15	83.6	COG0706@1|root,COG1887@1|root,COG0706@2|Bacteria,COG1887@2|Bacteria,1V0BX@1239|Firmicutes,24DWH@186801|Clostridia	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,Glyphos_transf
FNPCBABE_00694	428125.CLOLEP_01268	2.99e-91	279.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3WHR4@541000|Ruminococcaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
FNPCBABE_00695	428125.CLOLEP_01269	3.65e-194	554.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,3WGHG@541000|Ruminococcaceae	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
FNPCBABE_00696	428125.CLOLEP_01270	0.0	959.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,3WGGQ@541000|Ruminococcaceae	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
FNPCBABE_00697	484770.UFO1_4489	7.19e-86	261.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4H2EW@909932|Negativicutes	909932|Negativicutes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
FNPCBABE_00698	428125.CLOLEP_01273	1.62e-95	289.0	COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,2488X@186801|Clostridia,3WINS@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the ParB family	noc	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
FNPCBABE_00699	1121334.KB911079_gene450	1.29e-124	361.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3WGTZ@541000|Ruminococcaceae	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
FNPCBABE_00700	1121334.KB911079_gene449	4.83e-107	319.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3WHV1@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
FNPCBABE_00701	411469.EUBHAL_00349	9.68e-265	730.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,25VBF@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
FNPCBABE_00702	411902.CLOBOL_00823	3.49e-23	93.6	COG4640@1|root,COG4640@2|Bacteria,1VB94@1239|Firmicutes,24N0R@186801|Clostridia,2204Y@1506553|Lachnoclostridium	186801|Clostridia	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234,zinc_ribbon_2
FNPCBABE_00703	585394.RHOM_02160	5.35e-28	106.0	2DNQ7@1|root,32YJ2@2|Bacteria,1VFJY@1239|Firmicutes,24S09@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
FNPCBABE_00705	428125.CLOLEP_01281	3.41e-284	785.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3WGWJ@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
FNPCBABE_00706	1410670.JHXF01000004_gene1724	9.42e-133	387.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WHCD@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
FNPCBABE_00711	1121334.KB911066_gene970	4.33e-30	113.0	COG0642@1|root,COG2205@2|Bacteria,1VNVZ@1239|Firmicutes,24VI6@186801|Clostridia	186801|Clostridia	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Usp
FNPCBABE_00712	537013.CLOSTMETH_01390	2.41e-63	197.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3WIWI@541000|Ruminococcaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
FNPCBABE_00713	428125.CLOLEP_00277	6.25e-83	246.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
FNPCBABE_00714	1235835.C814_01664	2.35e-42	144.0	COG2246@1|root,COG2246@2|Bacteria,1V7CF@1239|Firmicutes,24KKV@186801|Clostridia,3WKZZ@541000|Ruminococcaceae	186801|Clostridia	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
FNPCBABE_00715	511680.BUTYVIB_01614	5.54e-132	385.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,4BXYN@830|Butyrivibrio	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
FNPCBABE_00717	1341157.RF007C_14565	4.82e-168	521.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,24BHM@186801|Clostridia,3WHJ5@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	GtrA,YfhO
FNPCBABE_00719	1507.HMPREF0262_02715	2.68e-47	154.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,36JME@31979|Clostridiaceae	186801|Clostridia	S	stage V sporulation protein	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
FNPCBABE_00720	428125.CLOLEP_02434	5.01e-129	379.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,3WH5S@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
FNPCBABE_00721	411471.SUBVAR_05541	1.35e-25	108.0	COG1277@1|root,COG1277@2|Bacteria,1UZXS@1239|Firmicutes,248ME@186801|Clostridia,3WI9V@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3
FNPCBABE_00722	428125.CLOLEP_02436	3.43e-94	303.0	COG3225@1|root,COG3225@2|Bacteria,1V597@1239|Firmicutes,25DA0@186801|Clostridia,3WSG9@541000|Ruminococcaceae	186801|Clostridia	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
FNPCBABE_00724	1449050.JNLE01000003_gene2058	1.04e-36	136.0	COG3279@1|root,COG3279@2|Bacteria,1UYV2@1239|Firmicutes,24J31@186801|Clostridia,36VM5@31979|Clostridiaceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
FNPCBABE_00725	411469.EUBHAL_03061	8.46e-116	336.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,25V9I@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
FNPCBABE_00726	697329.Rumal_2513	4.29e-158	447.0	2CJP6@1|root,2Z7MS@2|Bacteria,1U6CA@1239|Firmicutes,24D7D@186801|Clostridia,3WHP5@541000|Ruminococcaceae	186801|Clostridia	L	Eco47II restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_Eco47II
FNPCBABE_00727	697329.Rumal_2514	2.32e-215	600.0	COG0270@1|root,COG3655@1|root,COG0270@2|Bacteria,COG3655@2|Bacteria,1TSNX@1239|Firmicutes,2490C@186801|Clostridia,3WGPT@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,HTH_26
FNPCBABE_00728	411463.EUBVEN_01765	2.09e-176	510.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,25VSJ@186806|Eubacteriaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
FNPCBABE_00729	428125.CLOLEP_00230	2.94e-248	699.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3WHFZ@541000|Ruminococcaceae	186801|Clostridia	H	acetolactate synthase large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
FNPCBABE_00730	1134413.ANNK01000048_gene1009	1.75e-32	125.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,1ZB7T@1386|Bacillus	91061|Bacilli	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
FNPCBABE_00731	1203606.HMPREF1526_02718	1.08e-62	203.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,36DGZ@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
FNPCBABE_00732	665956.HMPREF1032_00709	8.62e-43	155.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3WGRD@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
FNPCBABE_00733	1391647.AVSV01000018_gene766	5.8e-216	612.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,36DWR@31979|Clostridiaceae	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
FNPCBABE_00734	1499683.CCFF01000016_gene781	0.0	934.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,36E5W@31979|Clostridiaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
FNPCBABE_00735	428125.CLOLEP_00223	5.46e-90	266.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3WIGV@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R10170	RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
FNPCBABE_00736	428125.CLOLEP_00224	4.04e-251	695.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3WG9G@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
FNPCBABE_00737	1449338.JQLU01000005_gene1801	2.47e-17	85.1	COG0664@1|root,COG0664@2|Bacteria,1VD7I@1239|Firmicutes,4HMTP@91061|Bacilli	91061|Bacilli	K	cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
FNPCBABE_00738	877415.JNJQ01000067_gene1796	9.02e-20	98.2	COG5492@1|root,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,3VRCS@526524|Erysipelotrichia	526524|Erysipelotrichia	N	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FIVAR,LRR_5,SdrD_B
FNPCBABE_00739	1403819.BATR01000092_gene2664	1.78e-49	175.0	COG0657@1|root,COG0657@2|Bacteria,46TVH@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,EF-hand_5
FNPCBABE_00740	1410658.JHWI01000013_gene803	5.06e-19	91.7	COG2207@1|root,COG2207@2|Bacteria,1V27P@1239|Firmicutes,3VUDX@526524|Erysipelotrichia	526524|Erysipelotrichia	K	COG COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
FNPCBABE_00741	1123311.KB904449_gene273	2.8e-25	108.0	COG2207@1|root,COG2207@2|Bacteria,1UZ0Q@1239|Firmicutes,4IPX1@91061|Bacilli	91061|Bacilli	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
FNPCBABE_00742	1507.HMPREF0262_01199	2.12e-34	137.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,24997@186801|Clostridia,36DTZ@31979|Clostridiaceae	186801|Clostridia	S	G5 domain protein	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
FNPCBABE_00745	457412.RSAG_00309	3.79e-122	369.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,3WG7K@541000|Ruminococcaceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
FNPCBABE_00746	457412.RSAG_00308	5.98e-104	299.0	2CUHA@1|root,32SVB@2|Bacteria,1V9BJ@1239|Firmicutes,24MJT@186801|Clostridia,3WK7H@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00747	1121115.AXVN01000009_gene1496	1.69e-184	513.0	COG4509@1|root,COG4509@2|Bacteria,1V7UG@1239|Firmicutes,24KBR@186801|Clostridia,3Y2BT@572511|Blautia	186801|Clostridia	S	Sortase family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
FNPCBABE_00748	457412.RSAG_00306	0.0	940.0	COG0741@1|root,COG0741@2|Bacteria,1V3F0@1239|Firmicutes,249C4@186801|Clostridia,3WSRH@541000|Ruminococcaceae	186801|Clostridia	M	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Lysozyme_like
FNPCBABE_00749	1160721.RBI_I01303	3.81e-75	225.0	COG1396@1|root,COG1396@2|Bacteria,1V62J@1239|Firmicutes,24I2F@186801|Clostridia,3WRJH@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
FNPCBABE_00750	457412.RSAG_00304	1.38e-37	125.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_17
FNPCBABE_00751	1160721.RBI_I01304	7.45e-167	466.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,3WIXV@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
FNPCBABE_00752	457412.RSAG_00302	4.37e-284	777.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia,3WJ5X@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
FNPCBABE_00753	1160721.RBI_I01306	3.81e-159	446.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WH0X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
FNPCBABE_00754	457412.RSAG_04734	0.0	1500.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,3WI3D@541000|Ruminococcaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
FNPCBABE_00755	1160721.RBI_I01308	6.17e-201	556.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,3WJ5P@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	DUF1294,Metallophos
FNPCBABE_00756	1160721.RBI_I01310	5.01e-91	267.0	COG1595@1|root,COG1595@2|Bacteria,1V53N@1239|Firmicutes,24INY@186801|Clostridia,3WSF1@541000|Ruminococcaceae	186801|Clostridia	K	Putative ATPase subunit of terminase (gpP-like)	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
FNPCBABE_00757	457412.RSAG_00293	9.96e-82	242.0	COG2337@1|root,COG2337@2|Bacteria,1V3VN@1239|Firmicutes,24IES@186801|Clostridia,3WP5F@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
FNPCBABE_00759	457412.RSAG_00291	0.0	1181.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,3WG7M@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
FNPCBABE_00760	585501.HMPREF6123_1456	5.46e-274	758.0	COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,24ADD@186801|Clostridia,2PQYT@265975|Oribacterium	186801|Clostridia	S	cog cog1672	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
FNPCBABE_00762	1007096.BAGW01000017_gene812	8.53e-49	174.0	COG3299@1|root,COG3299@2|Bacteria,1UYY1@1239|Firmicutes,24FCN@186801|Clostridia,2N6VA@216572|Oscillospiraceae	186801|Clostridia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
FNPCBABE_00772	411467.BACCAP_00296	2.5e-141	410.0	28IS3@1|root,2Z8R9@2|Bacteria,1TSHH@1239|Firmicutes,24CQ6@186801|Clostridia,268KW@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
FNPCBABE_00774	428125.CLOLEP_03662	7.14e-81	256.0	28MWX@1|root,2ZB45@2|Bacteria,1UZ34@1239|Firmicutes,24EV8@186801|Clostridia,3WIEZ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00775	1105031.HMPREF1141_0089	1.22e-107	328.0	28KHP@1|root,2ZA34@2|Bacteria,1TQEJ@1239|Firmicutes,249F6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
FNPCBABE_00776	1121334.KB911067_gene273	7.18e-200	565.0	COG1783@1|root,COG1783@2|Bacteria,1TT2C@1239|Firmicutes,24A7T@186801|Clostridia,3WHDS@541000|Ruminococcaceae	186801|Clostridia	S	Phage terminase, large subunit, PBSX family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
FNPCBABE_00777	1160721.RBI_II00396	1.18e-17	82.0	2EQ5U@1|root,33HS4@2|Bacteria,1V3H5@1239|Firmicutes,24VF0@186801|Clostridia,3WKPZ@541000|Ruminococcaceae	186801|Clostridia	S	Terminase small subunit	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_2
FNPCBABE_00778	936589.HMPREF1521_0546	3.94e-11	66.2	COG4269@1|root,COG4269@2|Bacteria,1VA3P@1239|Firmicutes,4H7YK@909932|Negativicutes	909932|Negativicutes	S	Bacterial protein of unknown function (DUF898)	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
FNPCBABE_00779	1408311.JNJM01000001_gene366	1.27e-29	108.0	COG4495@1|root,COG4495@2|Bacteria,1VHEX@1239|Firmicutes,24RC9@186801|Clostridia,2PTRE@265975|Oribacterium	186801|Clostridia	S	Domain of unknown function (DUF4176)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4176
FNPCBABE_00784	397278.JOJN01000003_gene1719	2.13e-09	61.2	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4DQIX@85009|Propionibacteriales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
FNPCBABE_00789	1235800.C819_00912	1.64e-23	93.6	COG4842@1|root,COG4842@2|Bacteria,1VGZJ@1239|Firmicutes,24QQC@186801|Clostridia,27PX2@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Proteins of 100 residues with WXG	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
FNPCBABE_00791	1410628.JNKS01000001_gene2468	4.81e-13	65.5	2BH28@1|root,32B2T@2|Bacteria,1VQDM@1239|Firmicutes,258R3@186801|Clostridia,27QGH@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00793	1410628.JNKS01000001_gene2470	1.52e-40	146.0	COG3279@1|root,COG3279@2|Bacteria,1VD3A@1239|Firmicutes,24MP2@186801|Clostridia,27QNH@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
FNPCBABE_00794	1235802.C823_03151	0.0	1470.0	COG0433@1|root,COG1674@1|root,COG1716@1|root,COG0433@2|Bacteria,COG1674@2|Bacteria,COG1716@2|Bacteria,1TRA4@1239|Firmicutes,249Z1@186801|Clostridia,25V6X@186806|Eubacteriaceae	186801|Clostridia	D	Type VII secretion protein EssC	essC	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FHA,FtsK_SpoIIIE
FNPCBABE_00796	665950.HMPREF1025_01631	1.58e-44	172.0	COG4676@1|root,COG4676@2|Bacteria,1VF8Z@1239|Firmicutes,24S72@186801|Clostridia,27PHZ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TPR_11
FNPCBABE_00799	1410633.JHWR01000003_gene604	2.2e-74	258.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,27IAE@186928|unclassified Lachnospiraceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16
FNPCBABE_00800	1347086.CCBA010000022_gene3008	2.08e-127	445.0	COG3188@1|root,COG4447@1|root,COG3188@2|Bacteria,COG4447@2|Bacteria,1TPTP@1239|Firmicutes,4HT4E@91061|Bacilli,1ZS4X@1386|Bacillus	91061|Bacilli	NU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3
FNPCBABE_00801	404380.Gbem_2153	5.29e-12	77.4	COG4251@1|root,COG4936@1|root,COG4251@2|Bacteria,COG4936@2|Bacteria	2|Bacteria	KT	Sensory domain found in PocR	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,GAF_2,GGDEF,HAMP,HATPase_c,HD,HD_5,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,PocR,Response_reg
FNPCBABE_00802	1410638.JHXJ01000018_gene565	3.85e-59	192.0	COG0745@1|root,COG0745@2|Bacteria,1V5YC@1239|Firmicutes,25BJK@186801|Clostridia,3WSAK@541000|Ruminococcaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
FNPCBABE_00803	1226322.HMPREF1545_02484	5.72e-50	163.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia,2N7DV@216572|Oscillospiraceae	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
FNPCBABE_00805	1280663.ATVR01000034_gene1406	6.17e-85	254.0	2DBP0@1|root,2ZA6P@2|Bacteria,1V58E@1239|Firmicutes,24GG5@186801|Clostridia,4BZ73@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00806	1232453.BAIF02000051_gene1068	4.67e-18	92.4	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,268DZ@186813|unclassified Clostridiales	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
FNPCBABE_00807	585394.RHOM_10215	0.0	951.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
FNPCBABE_00808	1340434.AXVA01000003_gene2397	3.35e-06	54.3	COG1525@1|root,COG1525@2|Bacteria,1V3MZ@1239|Firmicutes,4HHPS@91061|Bacilli,1ZFIZ@1386|Bacillus	91061|Bacilli	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
FNPCBABE_00809	1292035.H476_1483	4.2e-29	129.0	COG2898@1|root,COG2898@2|Bacteria,1U5FR@1239|Firmicutes,248XI@186801|Clostridia,25TVG@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
FNPCBABE_00810	411474.COPEUT_02294	5.06e-130	374.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
FNPCBABE_00811	1160721.RBI_I01635	3.88e-93	278.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,3WIMP@541000|Ruminococcaceae	186801|Clostridia	S	protein, hemolysin III	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
FNPCBABE_00812	140626.JHWB01000009_gene1467	1.07e-222	639.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia	186801|Clostridia	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
FNPCBABE_00813	1304880.JAGB01000002_gene1714	1.24e-119	370.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
FNPCBABE_00814	476272.RUMHYD_02676	9.62e-87	263.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24EFS@186801|Clostridia,3XYU2@572511|Blautia	186801|Clostridia	KT	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
FNPCBABE_00815	877421.AUJT01000010_gene524	1.3e-54	181.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,27KAH@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
FNPCBABE_00816	1121115.AXVN01000010_gene2779	1.06e-145	414.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3XYGV@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
FNPCBABE_00817	622312.ROSEINA2194_04398	2.69e-124	364.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia	186801|Clostridia	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
FNPCBABE_00818	1232443.BAIA02000126_gene1111	4.86e-135	390.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,267YJ@186813|unclassified Clostridiales	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
FNPCBABE_00819	658088.HMPREF0987_00941	4.46e-86	267.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,27IMT@186928|unclassified Lachnospiraceae	186801|Clostridia	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
FNPCBABE_00820	1280679.ATVX01000002_gene807	7.68e-296	811.0	COG1350@1|root,COG1350@2|Bacteria,1UI01@1239|Firmicutes,25E8Q@186801|Clostridia,4BWG1@830|Butyrivibrio	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
FNPCBABE_00821	1392491.JIAE01000001_gene771	1.23e-31	125.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,3WIK7@541000|Ruminococcaceae	186801|Clostridia	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
FNPCBABE_00823	1120746.CCNL01000014_gene2198	9.48e-223	627.0	COG0064@1|root,COG0064@2|Bacteria,2NNPK@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.12,6.3.5.6,6.3.5.7	ko:K01876,ko:K02434	ko00970,ko01100,map00970,map01100	M00359,M00360	R03905,R04212,R05577	RC00010,RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GatB_N,GatB_Yqey
FNPCBABE_00824	1120746.CCNL01000014_gene2197	2.17e-244	683.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
FNPCBABE_00825	1308866.J416_14497	4.68e-08	53.5	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,470W4@74385|Gracilibacillus	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
FNPCBABE_00826	1121334.KB911066_gene492	1.43e-316	874.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,3WHZH@541000|Ruminococcaceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
FNPCBABE_00827	865861.AZSU01000006_gene1224	1.23e-166	528.0	COG0577@1|root,COG1511@1|root,COG4591@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,COG4591@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,36E94@31979|Clostridiaceae	186801|Clostridia	V	Permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
FNPCBABE_00828	903814.ELI_1949	1.72e-115	336.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,25V4X@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
FNPCBABE_00829	428125.CLOLEP_00759	5.31e-108	314.0	COG1573@1|root,COG1573@2|Bacteria,1V267@1239|Firmicutes,24DFW@186801|Clostridia,3WIGX@541000|Ruminococcaceae	186801|Clostridia	L	Uracil-DNA glycosylase	udgA	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
FNPCBABE_00830	428125.CLOLEP_00762	4.62e-96	283.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24EHP@186801|Clostridia,3WRUR@541000|Ruminococcaceae	186801|Clostridia	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	-	-	2.3.1.8	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTAC
FNPCBABE_00831	1140001.I571_00989	3.7e-36	130.0	COG0454@1|root,COG0456@2|Bacteria,1V1RG@1239|Firmicutes,4HFN7@91061|Bacilli,4B31W@81852|Enterococcaceae	91061|Bacilli	K	Protease synthase and sporulation negative regulatory protein pai 1	paiA	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
FNPCBABE_00832	1034807.FBFL15_1362	1.24e-31	124.0	COG2819@1|root,COG2819@2|Bacteria,4NH6C@976|Bacteroidetes,1HY0J@117743|Flavobacteriia,2NUQN@237|Flavobacterium	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
FNPCBABE_00833	553973.CLOHYLEM_06959	1.46e-11	65.9	2BVD7@1|root,32QT8@2|Bacteria,1V6S8@1239|Firmicutes,24JJP@186801|Clostridia,2215X@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00835	679200.HMPREF9333_01548	6.93e-98	292.0	28HKD@1|root,2Z7V8@2|Bacteria,1TQV8@1239|Firmicutes,24RRP@186801|Clostridia	186801|Clostridia	S	type ii restriction enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00836	1160721.RBI_II00479	0.0	987.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,3WGXZ@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
FNPCBABE_00837	428125.CLOLEP_02936	4.41e-44	147.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
FNPCBABE_00838	1378168.N510_00681	6.26e-44	151.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes	1239|Firmicutes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
FNPCBABE_00839	1121334.KB911074_gene2487	3.35e-135	386.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3WH4A@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
FNPCBABE_00840	1121334.KB911074_gene2488	2.78e-83	247.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WICR@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
FNPCBABE_00841	428125.CLOLEP_02931	6.72e-84	251.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,3WJ0G@541000|Ruminococcaceae	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
FNPCBABE_00843	428125.CLOLEP_02929	6.59e-26	97.1	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,24QK0@186801|Clostridia,3WKQN@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
FNPCBABE_00844	428125.CLOLEP_02928	1.34e-54	184.0	2C2S8@1|root,33RGY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00845	289376.THEYE_A1384	1.49e-79	248.0	COG0796@1|root,COG0796@2|Bacteria,3J132@40117|Nitrospirae	40117|Nitrospirae	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
FNPCBABE_00846	1121335.Clst_2422	3.37e-12	67.4	COG4506@1|root,COG4506@2|Bacteria,1U49U@1239|Firmicutes,259FV@186801|Clostridia,3WKB8@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1934
FNPCBABE_00847	1120746.CCNL01000009_gene1026	3.4e-276	771.0	COG0018@1|root,COG0018@2|Bacteria,2NNSE@2323|unclassified Bacteria	2|Bacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
FNPCBABE_00849	138119.DSY0630	3.24e-08	53.9	COG1476@1|root,COG1476@2|Bacteria,1VEIS@1239|Firmicutes,24R6J@186801|Clostridia,265V1@186807|Peptococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
FNPCBABE_00851	573061.Clocel_1295	8.47e-34	140.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,36DSK@31979|Clostridiaceae	186801|Clostridia	S	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
FNPCBABE_00853	1408322.JHYK01000022_gene1741	5.17e-57	195.0	COG3757@1|root,COG3757@2|Bacteria,1V5MP@1239|Firmicutes,24HFV@186801|Clostridia,27JZA@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25
FNPCBABE_00854	523794.Lebu_1770	3.12e-37	132.0	COG1854@1|root,COG1854@2|Bacteria,379PQ@32066|Fusobacteria	32066|Fusobacteria	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
FNPCBABE_00855	1410670.JHXF01000005_gene997	6.21e-36	147.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,3WGCB@541000|Ruminococcaceae	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
FNPCBABE_00857	428125.CLOLEP_01125	2.57e-93	275.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,3WIDH@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
FNPCBABE_00858	1160721.RBI_II00637	4.38e-245	678.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate kinase	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
FNPCBABE_00859	697329.Rumal_0090	1.79e-133	384.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
FNPCBABE_00860	428125.CLOLEP_01129	4.05e-291	803.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3WGBI@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
FNPCBABE_00861	658086.HMPREF0994_00793	4.2e-88	261.0	COG1051@1|root,COG1051@2|Bacteria,1V6RA@1239|Firmicutes,25BSE@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
FNPCBABE_00862	1507.HMPREF0262_02364	2.44e-216	620.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,36EMB@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
FNPCBABE_00863	1507.HMPREF0262_02365	1.56e-234	666.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E4P@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
FNPCBABE_00864	445972.ANACOL_01687	1.37e-146	427.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,3WGK3@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
FNPCBABE_00865	411489.CLOL250_00996	2.05e-133	387.0	COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,25CBN@186801|Clostridia,36WSY@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
FNPCBABE_00866	428125.CLOLEP_01614	0.0	1046.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae	186801|Clostridia	J	translation elongation	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
FNPCBABE_00867	1336241.JAEB01000008_gene1087	0.0	899.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,25VFE@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
FNPCBABE_00868	1235798.C817_01523	5.74e-98	289.0	COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,24IBW@186801|Clostridia,27VN6@189330|Dorea	186801|Clostridia	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
FNPCBABE_00869	742733.HMPREF9469_03138	8.42e-206	585.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,21YBJ@1506553|Lachnoclostridium	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
FNPCBABE_00870	500632.CLONEX_01450	4.23e-69	217.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia	186801|Clostridia	G	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Mannitol_dh_C
FNPCBABE_00871	445973.CLOBAR_02029	1.39e-74	238.0	COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,24B85@186801|Clostridia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
FNPCBABE_00872	479437.Elen_1892	8.75e-78	246.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CVBT@84998|Coriobacteriia	84998|Coriobacteriia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
FNPCBABE_00873	336407.RBE_0002	3.68e-24	95.9	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,47FJQ@766|Rickettsiales	766|Rickettsiales	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
FNPCBABE_00874	457396.CSBG_00890	1.59e-137	395.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,36F6F@31979|Clostridiaceae	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
FNPCBABE_00877	428125.CLOLEP_01892	0.0	1160.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
FNPCBABE_00878	1235835.C814_00095	8.5e-154	447.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,3WGFB@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
FNPCBABE_00879	1120746.CCNL01000010_gene1427	4.13e-105	326.0	COG1559@1|root,COG1559@2|Bacteria,2NP75@2323|unclassified Bacteria	2|Bacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
FNPCBABE_00880	945021.TEH_19900	1.33e-19	89.4	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,4B32U@81852|Enterococcaceae	91061|Bacilli	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
FNPCBABE_00881	1203550.HMPREF1475_01179	3.09e-51	169.0	COG0693@1|root,COG0693@2|Bacteria,4NPUE@976|Bacteroidetes,2FMXF@200643|Bacteroidia	976|Bacteroidetes	S	DJ-1 family	thiJ	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
FNPCBABE_00882	762968.HMPREF9441_00004	6.41e-06	55.5	COG4552@1|root,COG4866@1|root,COG4552@2|Bacteria,COG4866@2|Bacteria,4NGJE@976|Bacteroidetes,2FNB2@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	Acetyltransf_9,DUF2156
FNPCBABE_00883	471870.BACINT_00694	2.72e-62	206.0	COG4866@1|root,COG4866@2|Bacteria,4NGJE@976|Bacteroidetes,2FNB2@200643|Bacteroidia,4AK9E@815|Bacteroidaceae	976|Bacteroidetes	S	Conserved protein	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	Acetyltransf_9,DUF2156
FNPCBABE_00884	1120746.CCNL01000010_gene1423	1.35e-83	254.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iNJ661.Rv3247c	Thymidylate_kin
FNPCBABE_00885	1160721.RBI_I01407	4.93e-94	284.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,249DJ@186801|Clostridia,3WGNR@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
FNPCBABE_00886	1122217.KB899613_gene1458	2.12e-273	756.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4H2WK@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
FNPCBABE_00889	556261.HMPREF0240_03860	7.65e-10	60.5	COG1396@1|root,COG1397@1|root,COG1396@2|Bacteria,COG1397@2|Bacteria,1TSKF@1239|Firmicutes,25DA4@186801|Clostridia,36VE3@31979|Clostridiaceae	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
FNPCBABE_00891	1497679.EP56_03795	2.79e-24	111.0	COG0582@1|root,COG0582@2|Bacteria,1VR8Y@1239|Firmicutes,4HTPV@91061|Bacilli,26MZJ@186820|Listeriaceae	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
FNPCBABE_00892	457405.FSDG_01171	2.58e-05	45.1	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
FNPCBABE_00893	1408306.JHXX01000005_gene1146	1.35e-133	394.0	COG1674@1|root,COG1674@2|Bacteria,1UYYW@1239|Firmicutes,24EN0@186801|Clostridia	186801|Clostridia	D	FtsK/SpoIIIE family	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
FNPCBABE_00895	1160721.RBI_I01565	8.41e-42	143.0	COG4824@1|root,COG4824@2|Bacteria,1V81B@1239|Firmicutes,24JF5@186801|Clostridia,3WKV1@541000|Ruminococcaceae	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
FNPCBABE_00896	397288.C806_00777	2.62e-11	71.6	COG0860@1|root,COG1705@1|root,COG5632@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,COG5632@2|Bacteria,1V7JY@1239|Firmicutes,24C0T@186801|Clostridia,27M0W@186928|unclassified Lachnospiraceae	186801|Clostridia	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Amidase_3,CW_7,CW_binding_1,Cu_amine_oxidN1,Glucosaminidase,PG_binding_1
FNPCBABE_00899	97139.C824_05139	3.16e-31	130.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,36EWJ@31979|Clostridiaceae	186801|Clostridia	M	LICD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
FNPCBABE_00900	877411.JMMA01000002_gene2599	5.31e-65	217.0	COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,247JP@186801|Clostridia,3WJ79@541000|Ruminococcaceae	186801|Clostridia	GM	epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
FNPCBABE_00901	1160721.RBI_I00539	2.15e-108	319.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3WHVP@541000|Ruminococcaceae	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score	tagH	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
FNPCBABE_00902	1160721.RBI_I00538	4.02e-88	270.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,248R0@186801|Clostridia,3WKBW@541000|Ruminococcaceae	186801|Clostridia	GM	ABC-2 type transporter	tagG	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
FNPCBABE_00903	1120746.CCNL01000011_gene1905	5.98e-100	308.0	COG0687@1|root,COG0687@2|Bacteria,2NPSD@2323|unclassified Bacteria	2|Bacteria	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
FNPCBABE_00904	1007096.BAGW01000017_gene904	5.47e-77	242.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,2N6TV@216572|Oscillospiraceae	186801|Clostridia	E	Binding-protein-dependent transport system inner membrane component	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
FNPCBABE_00905	1203606.HMPREF1526_02247	1.6e-74	235.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,36EF3@31979|Clostridiaceae	186801|Clostridia	P	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
FNPCBABE_00906	1507.HMPREF0262_00678	7.87e-148	432.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,36EAA@31979|Clostridiaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
FNPCBABE_00907	1216932.CM240_0788	2.72e-87	317.0	COG0366@1|root,COG0860@1|root,COG3664@1|root,COG0366@2|Bacteria,COG0860@2|Bacteria,COG3664@2|Bacteria,1TQSE@1239|Firmicutes,24C4V@186801|Clostridia,36GZS@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Big_2,CBM26,CBM53,CW_binding_1,Y_Y_Y
FNPCBABE_00909	1216932.CM240_1512	4.51e-82	259.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,36DUP@31979|Clostridiaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
FNPCBABE_00910	1121334.KB911070_gene1357	5.24e-43	151.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
FNPCBABE_00911	428125.CLOLEP_01537	3.3e-287	812.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,3WGP3@541000|Ruminococcaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
FNPCBABE_00912	428125.CLOLEP_00456	1.94e-67	215.0	COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,24A80@186801|Clostridia,3WKVW@541000|Ruminococcaceae	186801|Clostridia	S	glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
FNPCBABE_00913	428125.CLOLEP_00455	2.18e-193	550.0	COG0769@1|root,COG0769@2|Bacteria,1UHY9@1239|Firmicutes,25E6X@186801|Clostridia,3WHF5@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
FNPCBABE_00915	754027.HMPREF9554_03119	4.19e-76	234.0	COG0110@1|root,COG0110@2|Bacteria,2J8I3@203691|Spirochaetes	203691|Spirochaetes	S	Bacterial transferase hexapeptide (six repeats)	wbbJ	-	2.3.1.18,2.3.1.79	ko:K00633,ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
FNPCBABE_00916	428125.CLOLEP_01459	2.32e-188	536.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,3WH00@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
FNPCBABE_00917	588581.Cpap_2408	5.41e-36	131.0	COG0671@1|root,COG0671@2|Bacteria,1V7XD@1239|Firmicutes,25BF5@186801|Clostridia,3WS6D@541000|Ruminococcaceae	186801|Clostridia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
FNPCBABE_00919	1410632.JHWW01000004_gene1539	8.65e-104	306.0	COG1207@1|root,COG1207@2|Bacteria,1UR9G@1239|Firmicutes,257VV@186801|Clostridia,27IDQ@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
FNPCBABE_00920	483218.BACPEC_01832	1.58e-289	795.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,2688C@186813|unclassified Clostridiales	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
FNPCBABE_00921	1105031.HMPREF1141_1004	2.4e-176	518.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,36DBN@31979|Clostridiaceae	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
FNPCBABE_00922	1121334.KB911072_gene2672	2.27e-52	167.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3WJW1@541000|Ruminococcaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
FNPCBABE_00923	697329.Rumal_1263	1.34e-91	273.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3WHNZ@541000|Ruminococcaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
FNPCBABE_00924	1121334.KB911072_gene2674	5.4e-78	235.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3WIZR@541000|Ruminococcaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
FNPCBABE_00927	1267005.KB911256_gene1623	1.95e-25	113.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,3N6J2@45401|Hyphomicrobiaceae	1224|Proteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
FNPCBABE_00929	33035.JPJF01000135_gene5078	1.36e-21	97.1	COG1802@1|root,COG3935@1|root,COG1802@2|Bacteria,COG3935@2|Bacteria,1VX1Z@1239|Firmicutes,25EAV@186801|Clostridia	186801|Clostridia	K	Conserved phage C-terminus (Phg_2220_C)	-	-	-	-	-	-	-	-	-	-	-	-	Phg_2220_C
FNPCBABE_00935	428125.CLOLEP_01534	9.01e-27	102.0	2CARW@1|root,33CNX@2|Bacteria,1W1RF@1239|Firmicutes,24X6E@186801|Clostridia,3WQR2@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00936	1120746.CCNL01000008_gene857	3.48e-17	74.3	2C3DI@1|root,33B22@2|Bacteria	2|Bacteria	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
FNPCBABE_00937	428126.CLOSPI_02502	3.81e-15	82.4	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,3VQFQ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	-	-	-	-	-	-	-	-	-	Mem_trans
FNPCBABE_00938	1211844.CBLM010000028_gene1902	2.32e-65	205.0	COG0778@1|root,COG0778@2|Bacteria,1V3ZT@1239|Firmicutes,3VQKT@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
FNPCBABE_00939	883156.HMPREF9282_01288	1.25e-86	258.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,4H4AS@909932|Negativicutes	909932|Negativicutes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
FNPCBABE_00940	742765.HMPREF9457_01906	1.39e-146	421.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,27WHM@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
FNPCBABE_00941	1160721.RBI_I01026	1.4e-201	565.0	COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,248U0@186801|Clostridia,3WH02@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
FNPCBABE_00942	1408321.JNJD01000009_gene1864	3.08e-68	222.0	COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,24BEN@186801|Clostridia,27MHV@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992,ko:K11051	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC2_membrane,ABC2_membrane_3
FNPCBABE_00943	1410650.JHWL01000001_gene975	4.63e-105	315.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,4BY83@830|Butyrivibrio	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990,ko:K11050	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC_tran,DUF4162
FNPCBABE_00945	693746.OBV_28900	8.12e-39	135.0	COG3279@1|root,COG3279@2|Bacteria,1VA36@1239|Firmicutes,24NJ5@186801|Clostridia	186801|Clostridia	K	LytTr DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
FNPCBABE_00946	903814.ELI_3079	1.59e-24	104.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,25WNV@186806|Eubacteriaceae	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
FNPCBABE_00947	1385520.N802_00195	8.68e-32	128.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4FFZV@85021|Intrasporangiaceae	201174|Actinobacteria	DM	biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA,Wzz
FNPCBABE_00948	1123284.KB899059_gene800	1.12e-15	75.5	COG2148@1|root,COG2148@2|Bacteria,1V2YT@1239|Firmicutes,4IQ2I@91061|Bacilli	91061|Bacilli	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
FNPCBABE_00949	1410622.JNKY01000015_gene329	2.17e-133	384.0	COG1208@1|root,COG1208@2|Bacteria,1TPII@1239|Firmicutes,249GT@186801|Clostridia,27IPM@186928|unclassified Lachnospiraceae	186801|Clostridia	JM	Nucleotidyl transferase	rfbF	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
FNPCBABE_00950	1123288.SOV_3c03250	8.55e-192	539.0	COG0451@1|root,COG0451@2|Bacteria,1TQW7@1239|Firmicutes,4H3HE@909932|Negativicutes	909932|Negativicutes	M	CDP-glucose 4,6-dehydratase	rfbG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
FNPCBABE_00951	1235803.C825_04476	2e-109	327.0	COG0451@1|root,COG0451@2|Bacteria,4NT4N@976|Bacteroidetes,2FU55@200643|Bacteroidia	976|Bacteroidetes	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
FNPCBABE_00952	1123288.SOV_3c03190	7.48e-100	293.0	COG1898@1|root,COG1898@2|Bacteria,1V2VG@1239|Firmicutes,4H7IN@909932|Negativicutes	909932|Negativicutes	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	dTDP_sugar_isom
FNPCBABE_00953	1487921.DP68_03600	1.99e-50	177.0	COG1442@1|root,COG1442@2|Bacteria,1UY89@1239|Firmicutes,249RV@186801|Clostridia,36J5F@31979|Clostridiaceae	186801|Clostridia	M	Glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPCC,Glyco_transf_8
FNPCBABE_00954	1131730.BAVI_17107	1.18e-99	307.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,4HC0S@91061|Bacilli,1ZEMI@1386|Bacillus	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
FNPCBABE_00955	762982.HMPREF9442_02466	1.43e-36	139.0	COG1216@1|root,COG1216@2|Bacteria,4NSIF@976|Bacteroidetes,2G2Z9@200643|Bacteroidia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
FNPCBABE_00957	1121105.ATXL01000021_gene608	1.65e-34	129.0	COG2327@1|root,COG2327@2|Bacteria,1U2UA@1239|Firmicutes,4HX1X@91061|Bacilli	91061|Bacilli	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
FNPCBABE_00958	553218.CAMRE0001_2235	8.42e-108	337.0	COG2244@1|root,COG2244@2|Bacteria,1NIMS@1224|Proteobacteria,42N68@68525|delta/epsilon subdivisions,2YMNN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Polysaccharide biosynthesis protein	pglK	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
FNPCBABE_00959	1173027.Mic7113_5414	1.07e-60	203.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
FNPCBABE_00960	357809.Cphy_3682	1.6e-93	290.0	COG2327@1|root,COG2327@2|Bacteria,1V4VX@1239|Firmicutes,24C2N@186801|Clostridia,223PJ@1506553|Lachnoclostridium	186801|Clostridia	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
FNPCBABE_00961	913865.DOT_0753	8.21e-66	218.0	COG1035@1|root,COG1143@1|root,COG1035@2|Bacteria,COG1143@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia,262D4@186807|Peptococcaceae	186801|Clostridia	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N
FNPCBABE_00962	483218.BACPEC_02375	1.44e-190	540.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,25B1W@186801|Clostridia,2682F@186813|unclassified Clostridiales	186801|Clostridia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
FNPCBABE_00965	931626.Awo_c13900	1.33e-86	289.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,25X42@186806|Eubacteriaceae	186801|Clostridia	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
FNPCBABE_00966	1256908.HMPREF0373_02731	5.07e-138	394.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,25VM2@186806|Eubacteriaceae	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
FNPCBABE_00967	1256908.HMPREF0373_02733	0.0	1319.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25VH6@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
FNPCBABE_00968	1196322.A370_05925	9.03e-58	184.0	COG1713@1|root,COG1713@2|Bacteria,1UJ6P@1239|Firmicutes,25EWR@186801|Clostridia,36UST@31979|Clostridiaceae	186801|Clostridia	H	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
FNPCBABE_00969	483218.BACPEC_02832	3.39e-74	227.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,26B99@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score	KatE	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00970	515620.EUBELI_00022	8.5e-72	235.0	COG1376@1|root,COG1376@2|Bacteria,1UK0I@1239|Firmicutes,249X8@186801|Clostridia,25W21@186806|Eubacteriaceae	186801|Clostridia	V	L,D-transpeptidase catalytic domain	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Cu_amine_oxidN1,DUF5011,YkuD
FNPCBABE_00971	428125.CLOLEP_02455	0.0	1917.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
FNPCBABE_00972	875454.BAEW01000002_gene430	1.45e-13	70.5	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia,22HV7@1570339|Peptoniphilaceae	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_00973	246199.CUS_7787	0.0	979.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3WH5Y@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
FNPCBABE_00974	515620.EUBELI_01383	1.04e-64	206.0	COG1410@1|root,COG1410@2|Bacteria,1V7JJ@1239|Firmicutes,24AE1@186801|Clostridia,25WR6@186806|Eubacteriaceae	186801|Clostridia	E	NOG21937 non supervised orthologous group	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
FNPCBABE_00975	411473.RUMCAL_02159	2.22e-131	381.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia,3WH1U@541000|Ruminococcaceae	186801|Clostridia	E	5,10-methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
FNPCBABE_00976	1121344.JHZO01000006_gene1882	7.08e-200	568.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,3WHBI@541000|Ruminococcaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
FNPCBABE_00977	657322.FPR_10150	3.88e-169	515.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,3WGSN@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,PUD
FNPCBABE_00978	632245.CLP_2315	1.27e-165	509.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,36E5I@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3372,PUD
FNPCBABE_00979	1105031.HMPREF1141_1654	8.71e-86	259.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,36EUI@31979|Clostridiaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
FNPCBABE_00980	1160721.RBI_I01385	3.29e-239	663.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,3WGXI@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
FNPCBABE_00981	1410617.JHXH01000004_gene1288	0.0	1005.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3WG9R@541000|Ruminococcaceae	186801|Clostridia	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
FNPCBABE_00982	428125.CLOLEP_01573	0.0	994.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3WGEU@541000|Ruminococcaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
FNPCBABE_00983	717606.PaecuDRAFT_3233	1.92e-05	54.7	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,26T6Z@186822|Paenibacillaceae	91061|Bacilli	L	helicase involved in DNA repair and perhaps also replication	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2,RNase_T,ResIII
FNPCBABE_00985	903814.ELI_2078	4.61e-99	313.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,25UX6@186806|Eubacteriaceae	186801|Clostridia	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
FNPCBABE_00986	428125.CLOLEP_01540	3.66e-224	630.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,3WGQ1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
FNPCBABE_00987	411463.EUBVEN_00557	1.83e-136	407.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25UR4@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
FNPCBABE_00989	1384066.JAGT01000001_gene409	1.04e-48	165.0	COG0500@1|root,COG2226@2|Bacteria,1V53X@1239|Firmicutes,24IQW@186801|Clostridia	186801|Clostridia	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653,Methyltransf_11,Methyltransf_25
FNPCBABE_00990	1105031.HMPREF1141_0695	8.04e-83	256.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,36IDY@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
FNPCBABE_00991	622312.ROSEINA2194_03846	1.73e-57	194.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia	186801|Clostridia	H	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
FNPCBABE_00993	1400520.LFAB_08920	1.53e-07	55.5	COG1846@1|root,COG1846@2|Bacteria,1TTKD@1239|Firmicutes,4HQ62@91061|Bacilli,3F7T9@33958|Lactobacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
FNPCBABE_00994	622312.ROSEINA2194_02623	2.42e-266	747.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
FNPCBABE_00995	397290.C810_04095	0.0	894.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,27I9D@186928|unclassified Lachnospiraceae	186801|Clostridia	V	overlaps another CDS with the same product name	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
FNPCBABE_00996	767817.Desgi_1323	6.34e-80	254.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,2617G@186807|Peptococcaceae	186801|Clostridia	S	PFAM Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,LTD,Lactamase_B
FNPCBABE_00997	1499685.CCFJ01000046_gene3155	7.49e-15	69.3	2DR1Y@1|root,339TZ@2|Bacteria,1VK7M@1239|Firmicutes,4HR6A@91061|Bacilli,1ZKCJ@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3006)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3006
FNPCBABE_00998	1160721.RBI_II00013	2.24e-74	226.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,3WK7E@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
FNPCBABE_00999	1301100.HG529429_gene1895	1.86e-74	232.0	COG0745@1|root,COG0745@2|Bacteria,1TR8K@1239|Firmicutes,24973@186801|Clostridia,36GND@31979|Clostridiaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
FNPCBABE_01000	1540257.JQMW01000009_gene2929	6.69e-26	117.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,36DKF@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
FNPCBABE_01001	883114.HMPREF9709_01434	1.33e-203	582.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,22GKH@1570339|Peptoniphilaceae	186801|Clostridia	Q	AMP-binding enzyme	-	-	6.1.1.13	ko:K03367,ko:K04784	ko00473,ko01053,ko01503,ko02020,ko05150,map00473,map01053,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008,ko01504	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
FNPCBABE_01002	700015.Corgl_0446	4.1e-112	340.0	COG0019@1|root,COG0019@2|Bacteria,2GIT5@201174|Actinobacteria,4CUJG@84998|Coriobacteriia	84998|Coriobacteriia	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
FNPCBABE_01003	883114.HMPREF9709_01432	1.86e-30	108.0	COG0236@1|root,COG0236@2|Bacteria,1VEX6@1239|Firmicutes,24QWP@186801|Clostridia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
FNPCBABE_01004	1123313.ATUT01000031_gene1457	9.86e-186	538.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,3VP7P@526524|Erysipelotrichia	526524|Erysipelotrichia	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
FNPCBABE_01005	479437.Elen_2186	1.81e-75	241.0	COG2755@1|root,COG2755@2|Bacteria,2HUFA@201174|Actinobacteria,4CUEM@84998|Coriobacteriia	84998|Coriobacteriia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01006	1449050.JNLE01000003_gene2028	5.51e-275	788.0	COG0366@1|root,COG3291@1|root,COG0366@2|Bacteria,COG3291@2|Bacteria,1V0U1@1239|Firmicutes,24ZQ4@186801|Clostridia	186801|Clostridia	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
FNPCBABE_01007	398511.BpOF4_18570	2.21e-72	230.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,1ZCPY@1386|Bacillus	91061|Bacilli	S	hydrolases of the HAD superfamily	yxeH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
FNPCBABE_01013	1278311.AUAL01000001_gene160	1.2e-13	83.6	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF2357,Peptidase_S24
FNPCBABE_01014	246199.CUS_7883	2.39e-180	523.0	COG1401@1|root,COG1401@2|Bacteria,1TRK1@1239|Firmicutes,24EKG@186801|Clostridia,3WI4A@541000|Ruminococcaceae	186801|Clostridia	V	ATPase associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01015	877411.JMMA01000002_gene466	2.15e-29	117.0	COG0681@1|root,COG0681@2|Bacteria,1VH6F@1239|Firmicutes,259NA@186801|Clostridia,3WGDR@541000|Ruminococcaceae	186801|Clostridia	U	Peptidase S24-like	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
FNPCBABE_01017	1410617.JHXH01000001_gene722	8.96e-41	149.0	2EV14@1|root,33NG8@2|Bacteria,1VU24@1239|Firmicutes,24Z1N@186801|Clostridia,3WHPM@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01019	394503.Ccel_2580	1.6e-17	75.1	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia,36PXP@31979|Clostridiaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01020	411489.CLOL250_01350	1.96e-66	209.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,24DSN@186801|Clostridia,36GYE@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
FNPCBABE_01021	1321778.HMPREF1982_04106	5.46e-106	329.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,268JM@186813|unclassified Clostridiales	186801|Clostridia	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
FNPCBABE_01022	1688.BCUN_0929	2.94e-77	242.0	COG1708@1|root,COG1708@2|Bacteria,2I2HJ@201174|Actinobacteria,4D03E@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,NTP_transf_2
FNPCBABE_01023	1120746.CCNL01000017_gene3268	3.89e-89	275.0	COG0196@1|root,COG0196@2|Bacteria,2NPCV@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
FNPCBABE_01024	428125.CLOLEP_01760	1.72e-85	256.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,3WJNN@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
FNPCBABE_01025	428125.CLOLEP_01759	1.09e-104	314.0	COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,249MT@186801|Clostridia,3WHJW@541000|Ruminococcaceae	186801|Clostridia	EM	Carboxypeptidase	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	LysM,PG_binding_1,Peptidase_M14
FNPCBABE_01026	1410612.JNKO01000021_gene2808	1.02e-264	739.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia,2PQR5@265975|Oribacterium	186801|Clostridia	K	Putative DNA-binding domain	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_24,HTH_DeoR
FNPCBABE_01027	428125.CLOLEP_03720	0.0	979.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,3WGJR@541000|Ruminococcaceae	186801|Clostridia	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
FNPCBABE_01028	203119.Cthe_1399	2.24e-52	171.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24J98@186801|Clostridia,3WJY6@541000|Ruminococcaceae	186801|Clostridia	S	TIGRFAM C_GCAxxG_C_C family	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
FNPCBABE_01029	428125.CLOLEP_01451	0.0	988.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WGRU@541000|Ruminococcaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
FNPCBABE_01030	658088.HMPREF0987_00851	1.17e-27	105.0	2DSCR@1|root,33FK0@2|Bacteria,1VKCD@1239|Firmicutes,24QWS@186801|Clostridia,27NWD@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF3783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3783
FNPCBABE_01031	471875.RUMLAC_02584	2.25e-42	153.0	COG0561@1|root,COG0561@2|Bacteria,1U3W2@1239|Firmicutes,2486H@186801|Clostridia,3WJGV@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
FNPCBABE_01032	428125.CLOLEP_03261	1.03e-98	292.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3WGWR@541000|Ruminococcaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
FNPCBABE_01033	999411.HMPREF1092_01739	1.44e-79	246.0	COG1011@1|root,COG1011@2|Bacteria,1UIG9@1239|Firmicutes,25EMR@186801|Clostridia,36G1V@31979|Clostridiaceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
FNPCBABE_01034	641112.ACOK01000001_gene3581	2.55e-278	772.0	COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3WGXK@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
FNPCBABE_01035	428125.CLOLEP_03227	2.94e-259	716.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3WGUF@541000|Ruminococcaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
FNPCBABE_01036	428125.CLOLEP_03228	6.6e-279	770.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3WG9P@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
FNPCBABE_01037	428125.CLOLEP_03229	4.46e-248	693.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3WH6T@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
FNPCBABE_01038	1121334.KB911072_gene2558	2.84e-133	381.0	COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,2483I@186801|Clostridia,3WGZE@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	4.3.2.2,6.3.2.6	ko:K01756,ko:K01923	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559,R04591	RC00064,RC00162,RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
FNPCBABE_01041	428125.CLOLEP_00048	3.1e-26	115.0	COG1266@1|root,COG1266@2|Bacteria,1VKW2@1239|Firmicutes,24QJG@186801|Clostridia,3WM89@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
FNPCBABE_01042	411483.FAEPRAA2165_00680	7.96e-51	166.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,3WJHQ@541000|Ruminococcaceae	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
FNPCBABE_01043	428125.CLOLEP_02025	4.74e-206	581.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,3WGF6@541000|Ruminococcaceae	186801|Clostridia	P	Cystathionine beta-lyase family protein involved in aluminum resistance	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
FNPCBABE_01045	877411.JMMA01000002_gene1096	2.08e-106	322.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia,3WGHW@541000|Ruminococcaceae	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
FNPCBABE_01046	1120746.CCNL01000017_gene3115	1.69e-33	134.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	cel	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
FNPCBABE_01047	428125.CLOLEP_02021	2.32e-218	617.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3WG85@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
FNPCBABE_01048	574375.BAGA_29485	2.46e-84	274.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB2U@91061|Bacilli,1ZB5R@1386|Bacillus	91061|Bacilli	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
FNPCBABE_01049	428125.CLOLEP_01917	7.34e-70	224.0	28J28@1|root,2Z8YU@2|Bacteria,1UYKD@1239|Firmicutes,24GNR@186801|Clostridia,3WHPZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01050	1033737.CAEV01000092_gene1892	7.64e-41	155.0	COG1680@1|root,COG1680@2|Bacteria,1TRR5@1239|Firmicutes,249KP@186801|Clostridia,36H4V@31979|Clostridiaceae	186801|Clostridia	V	beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,Cu_amine_oxidN1,DUF3471,Gram_pos_anchor
FNPCBABE_01051	428125.CLOLEP_01918	6.36e-313	878.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WGKX@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
FNPCBABE_01055	1120746.CCNL01000010_gene1368	1.33e-91	283.0	COG1484@1|root,COG1484@2|Bacteria	2|Bacteria	L	DNA-dependent DNA replication	-	-	-	ko:K02315,ko:K07452	-	-	-	-	ko00000,ko01000,ko02048,ko03032	-	-	-	AAA_5,DUF4357,IstB_IS21
FNPCBABE_01056	428125.CLOLEP_00529	7.12e-73	237.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia,3WJJV@541000|Ruminococcaceae	186801|Clostridia	L	DnaD domain protein	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
FNPCBABE_01057	272562.CA_C2387	1.52e-24	94.7	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,36MNV@31979|Clostridiaceae	186801|Clostridia	S	TSCPD domain	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
FNPCBABE_01059	428125.CLOLEP_00764	3.03e-208	585.0	COG3635@1|root,COG3635@2|Bacteria,1TQ5S@1239|Firmicutes,248U6@186801|Clostridia,3WH2J@541000|Ruminococcaceae	186801|Clostridia	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
FNPCBABE_01060	428125.CLOLEP_00523	1.63e-194	548.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,3WG91@541000|Ruminococcaceae	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
FNPCBABE_01061	1507.HMPREF0262_03702	1.43e-23	106.0	2E0TS@1|root,32WBE@2|Bacteria,1VBFI@1239|Firmicutes,24M0A@186801|Clostridia,36NAB@31979|Clostridiaceae	186801|Clostridia	S	Prokaryotic RING finger family 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF2628,Prok-RING_1,zinc_ribbon_2
FNPCBABE_01062	663278.Ethha_2193	9.63e-129	374.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,3WH3P@541000|Ruminococcaceae	186801|Clostridia	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
FNPCBABE_01063	515622.bpr_I2051	5.75e-36	136.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,4BXA3@830|Butyrivibrio	186801|Clostridia	E	PHP domain	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
FNPCBABE_01064	1160721.RBI_I00718	7.43e-29	106.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,3WJVR@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
FNPCBABE_01065	908340.HMPREF9406_1343	8.92e-232	649.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,36DX6@31979|Clostridiaceae	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
FNPCBABE_01067	1120746.CCNL01000013_gene1962	4.08e-81	258.0	COG1527@1|root,COG1527@2|Bacteria	2|Bacteria	C	subunit (C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
FNPCBABE_01068	1105031.HMPREF1141_2648	8.48e-198	578.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,36EI6@31979|Clostridiaceae	186801|Clostridia	U	Belongs to the V-ATPase 116 kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
FNPCBABE_01069	697329.Rumal_3162	5.04e-17	79.7	COG0636@1|root,COG0636@2|Bacteria,1VF4U@1239|Firmicutes,25CR4@186801|Clostridia,3WJIE@541000|Ruminococcaceae	186801|Clostridia	C	ATP synthase subunit C	ntpK	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
FNPCBABE_01070	428125.CLOLEP_03319	1.88e-49	159.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,3WJWV@541000|Ruminococcaceae	186801|Clostridia	C	Archaeal vacuolar-type H -ATPase subunit F	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
FNPCBABE_01072	428125.CLOLEP_01896	1.55e-55	211.0	COG0658@1|root,COG0658@2|Bacteria,1VGSX@1239|Firmicutes,249H4@186801|Clostridia,3WKE7@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
FNPCBABE_01073	1262449.CP6013_2186	9.87e-28	118.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,36FMH@31979|Clostridiaceae	186801|Clostridia	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
FNPCBABE_01074	1121334.KB911072_gene2649	5.23e-61	195.0	COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,24I8W@186801|Clostridia,3WIWX@541000|Ruminococcaceae	186801|Clostridia	L	Ribonuclease M5	rnmV	-	3.1.26.8	ko:K05985	-	-	-	-	ko00000,ko01000	-	-	-	DUF4093,Toprim,Toprim_4
FNPCBABE_01075	357809.Cphy_3715	2.1e-21	90.5	COG4905@1|root,COG4905@2|Bacteria,1VA0H@1239|Firmicutes,24NAK@186801|Clostridia,2210T@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
FNPCBABE_01076	428125.CLOLEP_02644	1.02e-124	375.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WGDS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
FNPCBABE_01077	428125.CLOLEP_02951	1.68e-107	320.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,3WGED@541000|Ruminococcaceae	186801|Clostridia	OU	Psort location Cytoplasmic, score	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
FNPCBABE_01078	1105031.HMPREF1141_2936	5.95e-92	283.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,36EFN@31979|Clostridiaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
FNPCBABE_01079	428125.CLOLEP_02952	1.75e-224	665.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3WGRB@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the FtsK SpoIIIE SftA family	spoIIIE	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
FNPCBABE_01080	428125.CLOLEP_02954	5.92e-312	867.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,3WGM7@541000|Ruminococcaceae	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
FNPCBABE_01081	260799.BAS3966	4.2e-21	97.4	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9N3@91061|Bacilli,1ZGQD@1386|Bacillus	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,LTD,Lactamase_B
FNPCBABE_01082	1121115.AXVN01000001_gene1052	9.15e-226	630.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3XYHR@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
FNPCBABE_01083	428125.CLOLEP_01583	7.66e-54	173.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,24JAB@186801|Clostridia,3WISA@541000|Ruminococcaceae	186801|Clostridia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
FNPCBABE_01084	1235802.C823_01019	7.28e-21	84.7	COG3655@1|root,COG3655@2|Bacteria,1VM6P@1239|Firmicutes,24UWM@186801|Clostridia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
FNPCBABE_01086	1410661.JNKW01000001_gene755	6.52e-20	86.3	COG0671@1|root,COG0671@2|Bacteria,1VB2R@1239|Firmicutes,24MQ9@186801|Clostridia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
FNPCBABE_01087	1499683.CCFF01000017_gene1801	1.98e-265	747.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,36ERR@31979|Clostridiaceae	186801|Clostridia	E	asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
FNPCBABE_01088	693746.OBV_35770	1.42e-24	109.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia,2N6DP@216572|Oscillospiraceae	186801|Clostridia	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
FNPCBABE_01090	946235.CAER01000056_gene2928	1.34e-19	97.8	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,4HC8P@91061|Bacilli,23J2M@182709|Oceanobacillus	91061|Bacilli	S	Putative stage IV sporulation protein YqfD	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
FNPCBABE_01091	663278.Ethha_0207	1.71e-89	272.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,3WHB0@541000|Ruminococcaceae	186801|Clostridia	S	metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
FNPCBABE_01092	428125.CLOLEP_03963	5.26e-231	655.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,3WH9C@541000|Ruminococcaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
FNPCBABE_01093	411483.FAEPRAA2165_01818	4.99e-178	530.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WG7A@541000|Ruminococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
FNPCBABE_01094	1120746.CCNL01000009_gene1037	3.34e-119	362.0	COG1686@1|root,COG1686@2|Bacteria,2NPJT@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
FNPCBABE_01095	665956.HMPREF1032_01357	2.01e-68	211.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3WJ07@541000|Ruminococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
FNPCBABE_01096	411469.EUBHAL_01639	2.54e-80	242.0	COG0716@1|root,COG0716@2|Bacteria,1V465@1239|Firmicutes,24DQZ@186801|Clostridia,25W9A@186806|Eubacteriaceae	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
FNPCBABE_01097	515620.EUBELI_00188	1.06e-89	265.0	COG1917@1|root,COG1917@2|Bacteria,1TRVH@1239|Firmicutes,249JY@186801|Clostridia,25VK4@186806|Eubacteriaceae	186801|Clostridia	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,CMD,Cupin_2
FNPCBABE_01098	1262449.CP6013_3931	1.09e-67	209.0	COG0716@1|root,COG0716@2|Bacteria,1V4P0@1239|Firmicutes,24INM@186801|Clostridia,36VIX@31979|Clostridiaceae	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
FNPCBABE_01101	1514668.JOOA01000002_gene1442	1.95e-21	89.7	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,25KIW@186801|Clostridia,3WMDA@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
FNPCBABE_01102	641112.ACOK01000025_gene2768	7.07e-192	541.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,3WGZH@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the TtcA family	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
FNPCBABE_01103	515622.bpr_I0245	5.98e-51	191.0	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia,4BWYS@830|Butyrivibrio	186801|Clostridia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE,dCache_1
FNPCBABE_01104	767817.Desgi_3550	1.09e-06	59.7	COG0791@1|root,COG0791@2|Bacteria,1VS0A@1239|Firmicutes,24CV4@186801|Clostridia,264BM@186807|Peptococcaceae	186801|Clostridia	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01105	1280390.CBQR020000120_gene3147	1.47e-112	330.0	COG0510@1|root,COG0510@2|Bacteria,1TQW6@1239|Firmicutes,4HC1S@91061|Bacilli	91061|Bacilli	M	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
FNPCBABE_01106	203119.Cthe_0423	0.0	1392.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae	186801|Clostridia	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
FNPCBABE_01108	1122217.KB899572_gene1163	3.84e-49	178.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4H3EU@909932|Negativicutes	909932|Negativicutes	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
FNPCBABE_01109	428125.CLOLEP_03328	2.01e-186	530.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
FNPCBABE_01110	1378168.N510_00350	6.17e-28	102.0	COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes	1239|Firmicutes	S	Conserved protein	yuzA	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
FNPCBABE_01112	318464.IO99_13040	5.22e-85	265.0	COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes,24AQF@186801|Clostridia,36FZA@31979|Clostridiaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
FNPCBABE_01113	1384066.JAGT01000001_gene320	3.49e-128	394.0	COG0249@1|root,COG0249@2|Bacteria,1UYBJ@1239|Firmicutes,249T9@186801|Clostridia,3WSH2@541000|Ruminococcaceae	186801|Clostridia	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
FNPCBABE_01114	1158607.UAU_04291	2.56e-05	45.4	COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,4B3FF@81852|Enterococcaceae	91061|Bacilli	S	Bacterial protein of unknown function (DUF896)	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
FNPCBABE_01117	428125.CLOLEP_00295	0.0	1331.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,3WGVW@541000|Ruminococcaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
FNPCBABE_01118	1514668.JOOA01000002_gene2338	1.25e-85	258.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3WIEP@541000|Ruminococcaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
FNPCBABE_01119	457421.CBFG_05521	1.33e-66	224.0	28JZ6@1|root,2Z9PA@2|Bacteria,1UQ35@1239|Firmicutes,24F3U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01120	1120746.CCNL01000017_gene3207	7.06e-171	483.0	COG0462@1|root,COG0462@2|Bacteria,2NNP6@2323|unclassified Bacteria	2|Bacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
FNPCBABE_01121	941824.TCEL_02147	1.16e-64	215.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,36EN8@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
FNPCBABE_01122	397290.C810_02529	0.0	1548.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,27J0E@186928|unclassified Lachnospiraceae	186801|Clostridia	G	PEP-utilising enzyme, TIM barrel domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
FNPCBABE_01123	457412.RSAG_02996	2.86e-90	271.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia,3WGWP@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
FNPCBABE_01124	1414720.CBYM010000030_gene1692	7.09e-59	191.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia,36I2K@31979|Clostridiaceae	186801|Clostridia	C	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
FNPCBABE_01125	406124.ACPC01000022_gene4114	8.13e-22	95.5	COG1878@1|root,COG1878@2|Bacteria,1UFUJ@1239|Firmicutes,4HD9U@91061|Bacilli,1ZQPZ@1386|Bacillus	91061|Bacilli	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
FNPCBABE_01127	1160721.RBI_I02050	1.18e-309	846.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3WGTU@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
FNPCBABE_01128	1160721.RBI_II00016	1.5e-205	578.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,3WGFU@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
FNPCBABE_01129	500632.CLONEX_00534	3.33e-295	816.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
FNPCBABE_01130	428125.CLOLEP_02638	0.0	2137.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,3WG9X@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
FNPCBABE_01131	1160721.RBI_II00014	9.3e-185	522.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,3WH1G@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
FNPCBABE_01132	246199.CUS_5563	2.92e-33	124.0	COG3707@1|root,COG3707@2|Bacteria,1V9FH@1239|Firmicutes,24JZU@186801|Clostridia,3WJ90@541000|Ruminococcaceae	186801|Clostridia	K	ANTAR domain protein	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
FNPCBABE_01133	397287.C807_02916	3.3e-265	743.0	COG0004@1|root,COG0347@1|root,COG0004@2|Bacteria,COG0347@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,27ITM@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
FNPCBABE_01134	1120746.CCNL01000017_gene2937	0.0	949.0	COG3968@1|root,COG3968@2|Bacteria,2NP30@2323|unclassified Bacteria	2|Bacteria	S	Glutamine synthetase type III N terminal	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
FNPCBABE_01135	1160721.RBI_II00513	0.0	2652.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,3WHE2@541000|Ruminococcaceae	186801|Clostridia	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
FNPCBABE_01136	1160721.RBI_II00514	8.14e-307	842.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,3WGBX@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
FNPCBABE_01137	180332.JTGN01000005_gene2811	6.01e-171	506.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
FNPCBABE_01138	1246995.AFR_05900	1.17e-80	244.0	arCOG13037@1|root,3342X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01143	713586.KB900536_gene296	9.02e-12	69.7	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,1WVZ9@135613|Chromatiales	135613|Chromatiales	S	subfamily IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
FNPCBABE_01144	411489.CLOL250_02176	2.63e-46	177.0	COG3307@1|root,COG3307@2|Bacteria,1UK9W@1239|Firmicutes,25FS0@186801|Clostridia,36KWE@31979|Clostridiaceae	186801|Clostridia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
FNPCBABE_01145	1249480.B649_02635	7.59e-25	112.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,43AG1@68525|delta/epsilon subdivisions,2YT1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Hypothetical glycosyl hydrolase family 13	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
FNPCBABE_01146	545695.TREAZ_0035	1.38e-40	139.0	COG0735@1|root,COG0735@2|Bacteria	2|Bacteria	P	belongs to the Fur family	fur	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
FNPCBABE_01147	1410631.JHWZ01000003_gene1467	6.24e-94	277.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27IW7@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Rubrerythrin	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
FNPCBABE_01148	626939.HMPREF9443_01862	1.87e-29	104.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes	1239|Firmicutes	C	rubredoxin	rubR2	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
FNPCBABE_01149	411474.COPEUT_00176	3.31e-151	428.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
FNPCBABE_01151	596315.HMPREF0634_0750	3.28e-55	192.0	COG2267@1|root,COG2267@2|Bacteria,1UHVZ@1239|Firmicutes,25E4X@186801|Clostridia,25UPB@186804|Peptostreptococcaceae	186801|Clostridia	I	Protein of unknown function (DUF2974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974
FNPCBABE_01152	1160721.RBI_I00834	5.76e-237	680.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,3WHAU@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
FNPCBABE_01153	537011.PREVCOP_05487	1.34e-44	151.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp20	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
FNPCBABE_01155	548479.HMPREF0573_10770	2.95e-34	138.0	2C1YG@1|root,2ZAA0@2|Bacteria,2GV42@201174|Actinobacteria,4D7DB@85005|Actinomycetales	201174|Actinobacteria	S	Domain of unknown function (DUF4428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4428
FNPCBABE_01157	592026.GCWU0000282_002052	3.51e-56	185.0	2A1UJ@1|root,30Q3Q@2|Bacteria,1V50E@1239|Firmicutes,24ITX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01160	246199.CUS_7978	8.68e-74	229.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,24E7M@186801|Clostridia,3WJQ7@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K07694	ko02020,map02020	M00480	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
FNPCBABE_01161	1280681.AUJZ01000003_gene1919	4.58e-47	174.0	COG4585@1|root,COG4585@2|Bacteria,1V4GJ@1239|Firmicutes,24M3N@186801|Clostridia,4BYYX@830|Butyrivibrio	186801|Clostridia	T	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01162	511680.BUTYVIB_00504	5.94e-55	201.0	2DBJI@1|root,2Z9M2@2|Bacteria,1V4CA@1239|Firmicutes,24IGG@186801|Clostridia,4BYMF@830|Butyrivibrio	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
FNPCBABE_01164	471875.RUMLAC_00178	0.0	1011.0	COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,249YY@186801|Clostridia,3WMAS@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer	csn1	-	-	ko:K09952	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas9-BH,Cas9_PI,Cas9_REC,HNH_4
FNPCBABE_01166	386415.NT01CX_2411	0.0	960.0	COG3410@1|root,COG3410@2|Bacteria,1TT74@1239|Firmicutes,24CMS@186801|Clostridia,36HRC@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
FNPCBABE_01168	742723.HMPREF9477_00163	1.99e-123	362.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,27J5Z@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Radical_SAM C-terminal domain	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
FNPCBABE_01171	1120746.CCNL01000011_gene1788	1.89e-136	390.0	COG0528@1|root,COG0528@2|Bacteria,2NNRY@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06240	AA_kinase
FNPCBABE_01172	1160721.RBI_II00035	7.44e-67	209.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3WIRX@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
FNPCBABE_01173	1105031.HMPREF1141_0177	1.37e-108	320.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,36DDR@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
FNPCBABE_01174	1235835.C814_01567	8.46e-38	141.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,3WH2Z@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score 10.00	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
FNPCBABE_01175	428125.CLOLEP_02963	1.42e-159	460.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WGCN@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
FNPCBABE_01176	428125.CLOLEP_02964	1.17e-59	207.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WGQW@541000|Ruminococcaceae	186801|Clostridia	M	Metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
FNPCBABE_01177	428125.CLOLEP_02965	2.42e-184	520.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3WGBA@541000|Ruminococcaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
FNPCBABE_01178	428125.CLOLEP_02966	0.0	1859.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,3WGJN@541000|Ruminococcaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
FNPCBABE_01179	596315.HMPREF0634_0411	1.09e-61	212.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,25QVB@186804|Peptostreptococcaceae	186801|Clostridia	S	AI-2E family transporter	yhhT	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
FNPCBABE_01180	1120746.CCNL01000011_gene1780	1.28e-131	390.0	COG3705@1|root,COG3705@2|Bacteria,2NQXE@2323|unclassified Bacteria	2|Bacteria	E	Histidyl-tRNA synthetase	hisZ	-	2.4.2.17,6.1.1.21	ko:K00765,ko:K01892,ko:K02502	ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230	M00026,M00359,M00360	R01071,R03655	RC00055,RC00523,RC02819,RC03200	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
FNPCBABE_01181	1120746.CCNL01000011_gene1779	2.99e-107	313.0	COG0040@1|root,COG0040@2|Bacteria,2NPCD@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
FNPCBABE_01182	428125.CLOLEP_02970	1.77e-212	598.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,3WGCJ@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
FNPCBABE_01183	641112.ACOK01000104_gene601	2.95e-114	342.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,3WGEN@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
FNPCBABE_01184	428125.CLOLEP_02972	3.76e-87	261.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,3WH5P@541000|Ruminococcaceae	186801|Clostridia	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
FNPCBABE_01185	1235835.C814_00219	4.66e-95	285.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,24GBJ@186801|Clostridia,3WH1N@541000|Ruminococcaceae	186801|Clostridia	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
FNPCBABE_01186	1232443.BAIA02000077_gene312	1.36e-60	187.0	COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
FNPCBABE_01187	428125.CLOLEP_02974	3.11e-54	171.0	COG0140@1|root,COG0140@2|Bacteria,1VB6S@1239|Firmicutes,24MP1@186801|Clostridia,3WJ8Q@541000|Ruminococcaceae	186801|Clostridia	E	Phosphoribosyl-ATP	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
FNPCBABE_01189	428125.CLOLEP_02630	1.44e-166	481.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,3WG80@541000|Ruminococcaceae	186801|Clostridia	J	tRNA methylthiotransferase YqeV	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
FNPCBABE_01190	1120746.CCNL01000012_gene1927	1.87e-107	330.0	COG1649@1|root,COG1649@2|Bacteria,2NP67@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,GHL10
FNPCBABE_01191	398512.JQKC01000007_gene1164	1.55e-17	78.2	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,3WKTD@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
FNPCBABE_01192	1410617.JHXH01000013_gene23	4.88e-68	220.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,3WI75@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
FNPCBABE_01197	1196028.ALEF01000065_gene1554	0.00025	42.4	COG3311@1|root,COG3311@2|Bacteria,1VEEK@1239|Firmicutes,4HP7U@91061|Bacilli	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
FNPCBABE_01202	428127.EUBDOL_01509	9.78e-91	278.0	COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,3VRYU@526524|Erysipelotrichia	526524|Erysipelotrichia	L	RecT family	-	-	-	-	-	-	-	-	-	-	-	-	RecT
FNPCBABE_01204	1485543.JMME01000021_gene802	2.86e-45	157.0	2CV27@1|root,32SWP@2|Bacteria,1VBY4@1239|Firmicutes	1239|Firmicutes	S	Putative HNHc nuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNHc_6
FNPCBABE_01205	1232453.BAIF02000057_gene1144	5.04e-33	130.0	COG3935@1|root,COG3935@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4373,DnaB_2
FNPCBABE_01206	641107.CDLVIII_2063	2.84e-33	128.0	COG1484@1|root,COG1484@2|Bacteria,1V48P@1239|Firmicutes,24B2B@186801|Clostridia,36ER6@31979|Clostridiaceae	186801|Clostridia	L	PFAM IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
FNPCBABE_01207	641107.CDLVIII_1315	1.19e-37	130.0	2C6KN@1|root,32Y69@2|Bacteria,1VANX@1239|Firmicutes,24MNG@186801|Clostridia,36KM4@31979|Clostridiaceae	186801|Clostridia	S	VRR-NUC domain	-	-	-	-	-	-	-	-	-	-	-	-	VRR_NUC
FNPCBABE_01210	1232452.BAIB02000007_gene1640	3.95e-99	299.0	COG0175@1|root,COG0175@2|Bacteria,1TSMI@1239|Firmicutes,24A18@186801|Clostridia	186801|Clostridia	EH	Phosphoadenosine phosphosulfate reductase	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
FNPCBABE_01214	411465.PEPMIC_00730	6.41e-19	83.2	COG1403@1|root,COG1403@2|Bacteria,1VEKN@1239|Firmicutes,24RGF@186801|Clostridia,22HYW@1570339|Peptoniphilaceae	186801|Clostridia	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
FNPCBABE_01215	1211814.CAPG01000074_gene3458	1.01e-14	72.4	2C080@1|root,3338D@2|Bacteria,1VH6C@1239|Firmicutes,4HRRT@91061|Bacilli,1ZRVQ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01216	1203606.HMPREF1526_00981	2.15e-257	723.0	COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,36E5Y@31979|Clostridiaceae	186801|Clostridia	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
FNPCBABE_01217	626523.GCWU000342_01027	6.29e-138	406.0	COG4695@1|root,COG4695@2|Bacteria	2|Bacteria	N	Portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
FNPCBABE_01218	1158610.UC3_02352	9.02e-49	167.0	COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,4HBZH@91061|Bacilli,4B2WY@81852|Enterococcaceae	91061|Bacilli	OU	Clp protease	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
FNPCBABE_01219	397290.C810_00421	1.35e-83	268.0	COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes	1239|Firmicutes	S	phage major capsid protein, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
FNPCBABE_01221	457396.CSBG_01051	2.29e-11	62.8	COG5614@1|root,COG5614@2|Bacteria,1VKVN@1239|Firmicutes,25I6N@186801|Clostridia,36PE7@31979|Clostridiaceae	186801|Clostridia	S	head-tail adaptor	-	-	-	-	-	-	-	-	-	-	-	-	Phage_H_T_join
FNPCBABE_01222	1414720.CBYM010000040_gene1650	1.51e-37	132.0	2C0WF@1|root,3340E@2|Bacteria,1VEHS@1239|Firmicutes,24JQC@186801|Clostridia,36RK6@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01224	1321814.HMPREF9089_00935	2.49e-52	174.0	2DFCM@1|root,2ZRBY@2|Bacteria,1V500@1239|Firmicutes,25FKQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01227	33035.JPJF01000093_gene2243	1.1e-08	67.4	COG3941@1|root,COG5412@1|root,COG3941@2|Bacteria,COG5412@2|Bacteria,1TQDE@1239|Firmicutes,249I0@186801|Clostridia,3Y0ZQ@572511|Blautia	186801|Clostridia	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01229	585506.HMPREF0877_0162	6.92e-19	97.4	COG1196@1|root,COG4926@1|root,COG1196@2|Bacteria,COG4926@2|Bacteria,1UHNG@1239|Firmicutes,4IS4E@91061|Bacilli,4AXAX@81850|Leuconostocaceae	91061|Bacilli	L	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01230	1378168.N510_01416	2.51e-37	130.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes	1239|Firmicutes	K	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon	mntR_1	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
FNPCBABE_01231	1121289.JHVL01000064_gene299	1.54e-21	92.4	2ED9K@1|root,33761@2|Bacteria,1VEHV@1239|Firmicutes,24S9B@186801|Clostridia,36MUZ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01232	537013.CLOSTMETH_02184	4.96e-96	284.0	COG1073@1|root,COG1073@2|Bacteria,1U9AI@1239|Firmicutes,24B6Z@186801|Clostridia,3WHN9@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
FNPCBABE_01233	1120746.CCNL01000017_gene3231	0.0	916.0	COG2183@1|root,COG2183@2|Bacteria,2NP2S@2323|unclassified Bacteria	2|Bacteria	K	Tex-like protein N-terminal domain	yhgF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
FNPCBABE_01234	97139.C824_05257	9.91e-104	310.0	COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,24BU5@186801|Clostridia,36F4N@31979|Clostridiaceae	186801|Clostridia	P	Formate nitrite	fnt	-	-	ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.2	-	-	Form_Nir_trans
FNPCBABE_01235	411471.SUBVAR_05881	1.7e-43	153.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24JF9@186801|Clostridia,3WJRT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
FNPCBABE_01236	411470.RUMGNA_03224	1.59e-08	52.4	2EHCX@1|root,33B4S@2|Bacteria,1VKA0@1239|Firmicutes	1239|Firmicutes	S	Spore coat associated protein JA (CotJA)	-	-	-	-	-	-	-	-	-	-	-	-	CotJA
FNPCBABE_01237	272563.CD630_05970	1.87e-12	64.3	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia	186801|Clostridia	S	COG NOG18028 non supervised orthologous group	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
FNPCBABE_01238	1121335.Clst_2046	3.17e-09	53.5	COG3546@1|root,COG3546@2|Bacteria	2|Bacteria	P	catalase activity	cotJC	-	-	ko:K06334,ko:K07217	-	-	-	-	ko00000	-	-	-	Mn_catalase
FNPCBABE_01239	457412.RSAG_02474	3.72e-140	404.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,249AX@186801|Clostridia,3WJR3@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
FNPCBABE_01240	457412.RSAG_02475	7.05e-278	764.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WHBC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
FNPCBABE_01241	1160721.RBI_II00006	1.72e-14	73.9	COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,24MDJ@186801|Clostridia,3WSEJ@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
FNPCBABE_01242	1408323.JQKK01000009_gene1154	2.25e-79	241.0	COG1670@1|root,COG1670@2|Bacteria,1V4F3@1239|Firmicutes,24EZ6@186801|Clostridia,27IX6@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
FNPCBABE_01243	411474.COPEUT_02494	5.66e-141	400.0	COG1305@1|root,COG1305@2|Bacteria,1TS2V@1239|Firmicutes,24AFU@186801|Clostridia	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
FNPCBABE_01244	633697.EubceDRAFT1_1287	6.58e-112	334.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,25V8W@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
FNPCBABE_01245	537013.CLOSTMETH_00694	1.34e-61	196.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3WJIZ@541000|Ruminococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
FNPCBABE_01246	411463.EUBVEN_00590	8.73e-144	423.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,25VUJ@186806|Eubacteriaceae	186801|Clostridia	S	CobW P47K family protein	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
FNPCBABE_01248	97139.C824_02520	9.59e-111	327.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,36E89@31979|Clostridiaceae	186801|Clostridia	E	ABC transporter	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
FNPCBABE_01249	1121344.JHZO01000001_gene519	3.2e-82	251.0	COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,25C2S@186801|Clostridia,3WHKU@541000|Ruminococcaceae	186801|Clostridia	P	ABC transporter, permease protein	tcyB	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
FNPCBABE_01250	411469.EUBHAL_00834	2.1e-73	233.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,25VIV@186806|Eubacteriaceae	186801|Clostridia	ET	ABC transporter, substrate-binding protein, family 3	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
FNPCBABE_01251	1519439.JPJG01000060_gene1861	2.32e-94	298.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia,2N6BB@216572|Oscillospiraceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
FNPCBABE_01252	1121334.KB911080_gene1244	1.96e-78	238.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,3WHS3@541000|Ruminococcaceae	186801|Clostridia	P	PFAM Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
FNPCBABE_01253	1408311.JNJM01000002_gene1314	1.44e-132	377.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,2PQVZ@265975|Oribacterium	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
FNPCBABE_01254	518637.EUBIFOR_00112	1.12e-180	507.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,3VP0S@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	-	-	-	-	-	-	-	-	-	-	RmlD_sub_bind
FNPCBABE_01255	1410661.JNKW01000006_gene252	1.05e-251	689.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
FNPCBABE_01256	633697.EubceDRAFT1_0981	2.45e-195	543.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,25UUW@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
FNPCBABE_01257	1232453.BAIF02000026_gene4215	1.92e-219	610.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
FNPCBABE_01262	1235799.C818_02530	5.01e-254	705.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,27J6E@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
FNPCBABE_01263	1121115.AXVN01000001_gene1111	1.03e-32	120.0	COG1340@1|root,COG1340@2|Bacteria,1V7S0@1239|Firmicutes,24KZW@186801|Clostridia	186801|Clostridia	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
FNPCBABE_01264	1235793.C809_04026	4.55e-80	244.0	COG1180@1|root,COG1180@2|Bacteria,1UK6G@1239|Firmicutes,25FMZ@186801|Clostridia,27UKC@186928|unclassified Lachnospiraceae	186801|Clostridia	O	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
FNPCBABE_01265	1341157.RF007C_09930	1.09e-33	124.0	COG4720@1|root,COG4720@2|Bacteria,1VF2R@1239|Firmicutes,24QR3@186801|Clostridia,3WMJA@541000|Ruminococcaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
FNPCBABE_01266	1232453.BAIF02000002_gene1241	4.26e-94	286.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,24ABV@186801|Clostridia,267IY@186813|unclassified Clostridiales	186801|Clostridia	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
FNPCBABE_01267	638301.HMPREF0444_1301	9.81e-61	215.0	28HWX@1|root,2Z82S@2|Bacteria,1UGW9@1239|Firmicutes,4HU09@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01270	203275.BFO_1594	6.06e-48	155.0	COG1917@1|root,COG1917@2|Bacteria,4NWMU@976|Bacteroidetes,2FUS4@200643|Bacteroidia	976|Bacteroidetes	S	Cupin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
FNPCBABE_01271	1235800.C819_00658	3.62e-68	211.0	COG1247@1|root,COG1247@2|Bacteria,1V3XH@1239|Firmicutes,24HCN@186801|Clostridia,27N0Z@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
FNPCBABE_01272	428125.CLOLEP_01532	7.77e-218	611.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3WGI3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
FNPCBABE_01273	1160721.RBI_I01660	9.08e-67	204.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3WJG0@541000|Ruminococcaceae	186801|Clostridia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
FNPCBABE_01274	411473.RUMCAL_00117	3.27e-211	592.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WH1M@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
FNPCBABE_01275	411467.BACCAP_01256	1.95e-66	206.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,269HS@186813|unclassified Clostridiales	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
FNPCBABE_01276	1336241.JAEB01000011_gene2108	8.34e-66	206.0	2BYWB@1|root,32SGE@2|Bacteria,1V4H1@1239|Firmicutes,25CVU@186801|Clostridia,25ZJB@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3793)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
FNPCBABE_01277	1268072.PSAB_06350	7.55e-10	68.2	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V13G@1239|Firmicutes,4I9SE@91061|Bacilli,271XK@186822|Paenibacillaceae	91061|Bacilli	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
FNPCBABE_01278	742735.HMPREF9467_02854	1.93e-34	122.0	COG2608@1|root,COG2608@2|Bacteria,1VEMB@1239|Firmicutes,24REK@186801|Clostridia,220T7@1506553|Lachnoclostridium	186801|Clostridia	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA,P12
FNPCBABE_01279	411473.RUMCAL_03001	5.63e-218	637.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,247QW@186801|Clostridia,3WH6Z@541000|Ruminococcaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
FNPCBABE_01280	411463.EUBVEN_01417	4.06e-134	383.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,25V4X@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
FNPCBABE_01282	1160721.RBI_I00823	0.0	1239.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WGIX@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
FNPCBABE_01283	1410632.JHWW01000002_gene1956	4.77e-37	125.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,27PNN@186928|unclassified Lachnospiraceae	186801|Clostridia	P	FeoA	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
FNPCBABE_01284	693746.OBV_37940	1.1e-29	106.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,2N7Q6@216572|Oscillospiraceae	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
FNPCBABE_01285	1410617.JHXH01000009_gene1645	9.28e-44	152.0	COG0664@1|root,COG0664@2|Bacteria,1V8K7@1239|Firmicutes,24JZ5@186801|Clostridia,3WPPC@541000|Ruminococcaceae	186801|Clostridia	K	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
FNPCBABE_01286	246199.CUS_7762	0.0	1223.0	COG1327@1|root,COG1328@1|root,COG1327@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3WHPK@541000|Ruminococcaceae	186801|Clostridia	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
FNPCBABE_01287	1504823.CCMM01000012_gene2171	5.16e-88	263.0	COG0602@1|root,COG0602@2|Bacteria	2|Bacteria	H	queuosine metabolic process	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
FNPCBABE_01288	1280682.AUKA01000010_gene106	1.5e-13	72.0	2EFW8@1|root,339NG@2|Bacteria,1VI6U@1239|Firmicutes,24UK7@186801|Clostridia,4C05M@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01289	428125.CLOLEP_02735	1.1e-221	619.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3WHC9@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
FNPCBABE_01290	428125.CLOLEP_02733	7.81e-182	519.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3WGG4@541000|Ruminococcaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
FNPCBABE_01291	536232.CLM_3488	1.18e-73	265.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,36E3C@31979|Clostridiaceae	186801|Clostridia	M	penicillin-binding protein 1A	mrcB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
FNPCBABE_01293	877420.ATVW01000013_gene1889	2.17e-138	401.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia,27IQ1@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Nitronate monooxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
FNPCBABE_01294	428125.CLOLEP_02717	6.2e-126	368.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3WGWD@541000|Ruminococcaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
FNPCBABE_01295	97139.C824_01712	5.43e-80	248.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,36EGR@31979|Clostridiaceae	186801|Clostridia	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
FNPCBABE_01296	1120746.CCNL01000006_gene340	6.28e-187	531.0	COG0304@1|root,COG0304@2|Bacteria,2NNSX@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
FNPCBABE_01297	35841.BT1A1_2172	6.32e-28	108.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,1ZGFF@1386|Bacillus	91061|Bacilli	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
FNPCBABE_01298	877420.ATVW01000013_gene1893	8.1e-48	157.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,27MSY@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
FNPCBABE_01299	394503.Ccel_0934	2e-215	607.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,36DJ8@31979|Clostridiaceae	186801|Clostridia	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
FNPCBABE_01300	428125.CLOLEP_02724	1.72e-125	368.0	COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,3WGZ8@541000|Ruminococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
FNPCBABE_01301	428125.CLOLEP_02725	3.81e-130	375.0	COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,25E47@186801|Clostridia,3WSKG@541000|Ruminococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
FNPCBABE_01303	1121115.AXVN01000104_gene843	6.02e-240	675.0	COG0437@1|root,COG4624@1|root,COG0437@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,3XYSR@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
FNPCBABE_01304	641112.ACOK01000055_gene3805	4.67e-42	151.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia,3WIGF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
FNPCBABE_01307	1282664.H354_09836	4.74e-19	79.7	COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,4HNIW@91061|Bacilli	91061|Bacilli	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
FNPCBABE_01308	411463.EUBVEN_01864	3.1e-39	141.0	COG0571@1|root,COG0571@2|Bacteria,1UYIA@1239|Firmicutes,24CBC@186801|Clostridia,25Y4U@186806|Eubacteriaceae	186801|Clostridia	K	Double-stranded RNA binding motif	-	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
FNPCBABE_01309	585394.RHOM_15120	1.85e-18	77.4	2C3TZ@1|root,33DSH@2|Bacteria,1VM6H@1239|Firmicutes,254ZM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01310	1507.HMPREF0262_00031	7.67e-105	306.0	2DZPR@1|root,32VFM@2|Bacteria,1VC7J@1239|Firmicutes,24NY3@186801|Clostridia,36SM5@31979|Clostridiaceae	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
FNPCBABE_01311	428125.CLOLEP_03818	1.7e-51	166.0	2C5R4@1|root,31VPY@2|Bacteria,1V8EP@1239|Firmicutes,24JPJ@186801|Clostridia,3WJKA@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
FNPCBABE_01312	180332.JTGN01000003_gene2019	1.08e-314	896.0	COG2932@1|root,COG4694@1|root,COG2932@2|Bacteria,COG4694@2|Bacteria,1TQ19@1239|Firmicutes,25B75@186801|Clostridia	186801|Clostridia	K	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_13
FNPCBABE_01313	1123234.AUKI01000016_gene2993	0.0	1069.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,4NM4C@976|Bacteroidetes	976|Bacteroidetes	L	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
FNPCBABE_01314	585394.RHOM_10835	1.48e-126	370.0	COG1715@1|root,COG1715@2|Bacteria,1V7W8@1239|Firmicutes,25CUM@186801|Clostridia	186801|Clostridia	L	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_N,Mrr_cat
FNPCBABE_01315	1235799.C818_03964	7.01e-186	525.0	COG1846@1|root,COG2184@1|root,COG1846@2|Bacteria,COG2184@2|Bacteria,1TNY6@1239|Firmicutes,249XE@186801|Clostridia,27KEX@186928|unclassified Lachnospiraceae	186801|Clostridia	D	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
FNPCBABE_01316	1408436.JHXY01000049_gene257	3.91e-119	343.0	COG2184@1|root,COG2184@2|Bacteria,1TPUZ@1239|Firmicutes,248XF@186801|Clostridia,25W8Z@186806|Eubacteriaceae	186801|Clostridia	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Bro-N,Fic
FNPCBABE_01317	1256908.HMPREF0373_01165	6.72e-45	152.0	2C15H@1|root,332DU@2|Bacteria,1VIK1@1239|Firmicutes,24RAR@186801|Clostridia,25XY7@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01318	1507.HMPREF0262_00047	1.22e-36	124.0	COG3311@1|root,COG3311@2|Bacteria,1VFSN@1239|Firmicutes,24S51@186801|Clostridia,36PPB@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
FNPCBABE_01319	428125.CLOLEP_03808	1.72e-66	209.0	2DM9Q@1|root,329N9@2|Bacteria,1VQK9@1239|Firmicutes,24UVD@186801|Clostridia,3WRZH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01321	428125.CLOLEP_03812	4.4e-36	124.0	2DRZ1@1|root,33DRR@2|Bacteria,1VQMR@1239|Firmicutes,24UWB@186801|Clostridia,3WMDU@541000|Ruminococcaceae	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
FNPCBABE_01322	1507.HMPREF0262_00051	1.03e-145	421.0	COG0468@1|root,COG0468@2|Bacteria,1V9SB@1239|Firmicutes,25E2S@186801|Clostridia,36UGZ@31979|Clostridiaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
FNPCBABE_01323	1507.HMPREF0262_00052	4.11e-13	66.6	2DW4M@1|root,33YI1@2|Bacteria,1VNGI@1239|Firmicutes,25227@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01324	877414.ATWA01000005_gene696	2.59e-129	390.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,248VT@186801|Clostridia,267ZY@186813|unclassified Clostridiales	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
FNPCBABE_01325	1507.HMPREF0262_00054	4.5e-158	450.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,36HAM@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
FNPCBABE_01326	428125.CLOLEP_03840	5.1e-237	658.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247VU@186801|Clostridia,3WIAF@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
FNPCBABE_01328	1384065.JAGS01000001_gene3244	2.27e-154	455.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia,3WJKE@541000|Ruminococcaceae	186801|Clostridia	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
FNPCBABE_01329	428125.CLOLEP_02009	3.01e-38	129.0	COG1396@1|root,COG1396@2|Bacteria,1VJNB@1239|Firmicutes,24TZB@186801|Clostridia	186801|Clostridia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
FNPCBABE_01330	1519439.JPJG01000055_gene2199	2.24e-266	747.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,2N6Y1@216572|Oscillospiraceae	186801|Clostridia	F	Adenine deaminase C-terminal domain	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
FNPCBABE_01331	1160721.RBI_I00653	2.29e-215	600.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,3WMZC@541000|Ruminococcaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	gldA	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
FNPCBABE_01332	1235792.C808_02449	1.75e-238	665.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,27JSN@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
FNPCBABE_01333	537013.CLOSTMETH_03415	9.37e-68	217.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia,3WPVF@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator DeoR family	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
FNPCBABE_01334	411460.RUMTOR_00802	6.21e-219	606.0	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,24AVD@186801|Clostridia,3XZZ3@572511|Blautia	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	ko:K18471	ko00640,map00640	-	R10718	RC00739	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
FNPCBABE_01335	411460.RUMTOR_00803	4.26e-159	454.0	COG0524@1|root,COG0524@2|Bacteria,1UYF8@1239|Firmicutes,25MKN@186801|Clostridia,3Y0ZH@572511|Blautia	186801|Clostridia	G	Phosphomethylpyrimidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
FNPCBABE_01336	1232447.BAHW02000009_gene336	1.1e-191	533.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,268GH@186813|unclassified Clostridiales	186801|Clostridia	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
FNPCBABE_01337	1232453.BAIF02000087_gene258	6.03e-216	600.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24FHS@186801|Clostridia	186801|Clostridia	E	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
FNPCBABE_01338	1235792.C808_02440	4.16e-267	739.0	COG2271@1|root,COG2271@2|Bacteria,1UHSG@1239|Firmicutes,249UT@186801|Clostridia,27RBF@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Sugar (and other) transporter	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,Sugar_tr
FNPCBABE_01339	1232447.BAHW02000009_gene333	5.05e-142	403.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,268XI@186813|unclassified Clostridiales	186801|Clostridia	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783,ko:K17195	ko00030,ko00040,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529,R09031	RC00540,RC03111	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
FNPCBABE_01340	1235792.C808_02438	4.3e-233	644.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,2493N@186801|Clostridia,27TH1@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Glucose dehydrogenase C-terminus	-	-	1.1.1.103,1.1.1.14	ko:K00008,ko:K00060	ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100	M00014	R00875,R01465,R01896	RC00085,RC00102,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
FNPCBABE_01341	428125.CLOLEP_02484	0.0	1298.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3WHFT@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
FNPCBABE_01343	877414.ATWA01000045_gene1862	1.07e-48	157.0	COG0758@1|root,COG0758@2|Bacteria	2|Bacteria	LU	DNA mediated transformation	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,DUF2493,MoCo_carrier
FNPCBABE_01344	1378168.N510_01349	1.61e-19	80.1	2EJ02@1|root,33CR7@2|Bacteria,1VPEQ@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Arc
FNPCBABE_01346	1280676.AUJO01000002_gene1682	5.28e-211	601.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,4BW9U@830|Butyrivibrio	186801|Clostridia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K01176,ko:K05343	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
FNPCBABE_01349	1519439.JPJG01000008_gene1197	1.08e-147	426.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,2N7GX@216572|Oscillospiraceae	186801|Clostridia	S	Macro domain	-	-	-	-	-	-	-	-	-	-	-	-	Macro
FNPCBABE_01350	1519439.JPJG01000007_gene1206	4.63e-107	313.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,249HV@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01351	397291.C804_04364	3.39e-39	154.0	COG5305@1|root,COG5305@2|Bacteria,1UXXF@1239|Firmicutes,25Q2P@186801|Clostridia,27NZC@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
FNPCBABE_01353	1235835.C814_01774	1.04e-282	795.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,3WGTB@541000|Ruminococcaceae	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
FNPCBABE_01354	1235797.C816_02297	1.19e-287	805.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,2N70B@216572|Oscillospiraceae	186801|Clostridia	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
FNPCBABE_01355	1378168.N510_02309	1.08e-95	318.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes	1239|Firmicutes	M	Belongs to the LTA synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
FNPCBABE_01356	1280681.AUJZ01000004_gene2925	6.51e-13	79.3	COG0810@1|root,COG3210@1|root,COG5279@1|root,COG5492@1|root,COG0810@2|Bacteria,COG3210@2|Bacteria,COG5279@2|Bacteria,COG5492@2|Bacteria,1V4SN@1239|Firmicutes,24HXN@186801|Clostridia,4BXIE@830|Butyrivibrio	186801|Clostridia	DU	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new,LRR_5,Transglut_core
FNPCBABE_01357	1256908.HMPREF0373_02590	3.77e-32	137.0	COG3209@1|root,COG5279@1|root,COG3209@2|Bacteria,COG5279@2|Bacteria,1V8TE@1239|Firmicutes,24CI3@186801|Clostridia,25XC1@186806|Eubacteriaceae	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CW_binding_2,Cu_amine_oxidN1,Transglut_core
FNPCBABE_01358	1297617.JPJD01000034_gene748	4.65e-60	197.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,268T1@186813|unclassified Clostridiales	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
FNPCBABE_01359	428125.CLOLEP_00361	5.64e-174	490.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,3WGC5@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
FNPCBABE_01360	552398.HMPREF0866_02334	6e-51	173.0	COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,24CFP@186801|Clostridia,3WJQE@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
FNPCBABE_01361	357809.Cphy_3785	3.2e-271	766.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,222FN@1506553|Lachnoclostridium	186801|Clostridia	G	Galactose mutarotase-like	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF5110,Gal_mutarotas_2,Glyco_hydro_31
FNPCBABE_01362	1232446.BAIE02000015_gene1253	1.75e-32	127.0	COG1476@1|root,COG1476@2|Bacteria,1V36C@1239|Firmicutes,24933@186801|Clostridia,26980@186813|unclassified Clostridiales	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
FNPCBABE_01363	428125.CLOLEP_02426	1.04e-246	691.0	COG1109@1|root,COG1109@2|Bacteria,1TS6S@1239|Firmicutes,2491F@186801|Clostridia,3WN8S@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
FNPCBABE_01364	1256908.HMPREF0373_03429	7.81e-89	272.0	2F9WQ@1|root,34265@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01365	1256908.HMPREF0373_03441	0.0	1211.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,25XM1@186806|Eubacteriaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,T4SS-DNA_transf,Zn_ribbon_recom
FNPCBABE_01366	1256908.HMPREF0373_03440	8.4e-85	250.0	2C5R4@1|root,2ZBQ6@2|Bacteria,1V1T6@1239|Firmicutes,24GMD@186801|Clostridia,25X2W@186806|Eubacteriaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
FNPCBABE_01367	1256908.HMPREF0373_03439	1.46e-38	128.0	2FGU8@1|root,348PJ@2|Bacteria,1W0KZ@1239|Firmicutes,24QZ0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01368	1256908.HMPREF0373_03437	5.27e-64	195.0	2EJ89@1|root,33CZF@2|Bacteria,1VNWZ@1239|Firmicutes,24RJS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01369	1256908.HMPREF0373_03436	0.0	907.0	28JIM@1|root,2Z9BV@2|Bacteria,1TRP9@1239|Firmicutes,24DM5@186801|Clostridia,25VV2@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01370	1256908.HMPREF0373_03433	0.0	940.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,25VCP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	VirE
FNPCBABE_01371	1256908.HMPREF0373_03432	1.91e-31	110.0	2DY2E@1|root,347TF@2|Bacteria,1VYZ0@1239|Firmicutes,2537A@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
FNPCBABE_01372	1226322.HMPREF1545_00225	3.18e-88	258.0	COG3276@1|root,COG3276@2|Bacteria,1V4T9@1239|Firmicutes,25022@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01373	537013.CLOSTMETH_01950	2.98e-42	145.0	COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,24HSJ@186801|Clostridia,3WJ3S@541000|Ruminococcaceae	186801|Clostridia	S	PFAM nucleoside recognition domain protein	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
FNPCBABE_01374	428125.CLOLEP_00404	1.3e-57	187.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,249G0@186801|Clostridia,3WKEB@541000|Ruminococcaceae	186801|Clostridia	S	membrane protein required for spore maturation	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
FNPCBABE_01376	428125.CLOLEP_02917	3.22e-83	249.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,3WJ3A@541000|Ruminococcaceae	186801|Clostridia	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
FNPCBABE_01377	1485543.JMME01000006_gene442	1.04e-16	82.8	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,4H6EH@909932|Negativicutes	909932|Negativicutes	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
FNPCBABE_01378	641112.ACOK01000112_gene2150	2.42e-58	187.0	COG1309@1|root,COG1309@2|Bacteria,1V73E@1239|Firmicutes,25B5N@186801|Clostridia,3WJEZ@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
FNPCBABE_01379	203119.Cthe_1480	0.0	885.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,3WGDU@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
FNPCBABE_01380	203119.Cthe_1481	4.52e-84	291.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,3WGGJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
FNPCBABE_01381	1007096.BAGW01000021_gene434	5.28e-28	102.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia,2N7NG@216572|Oscillospiraceae	186801|Clostridia	S	Small, acid-soluble spore proteins, alpha/beta type	-	-	-	-	-	-	-	-	-	-	-	-	SASP
FNPCBABE_01383	1120746.CCNL01000009_gene1018	1.17e-280	781.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iYL1228.KPN_03016	HMGL-like,LeuA_dimer
FNPCBABE_01387	428125.CLOLEP_00448	3.37e-34	117.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
FNPCBABE_01388	428125.CLOLEP_00447	5.35e-74	231.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,24K0D@186801|Clostridia,3WJN0@541000|Ruminococcaceae	186801|Clostridia	S	peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
FNPCBABE_01389	1120746.CCNL01000011_gene1688	1.4e-80	249.0	COG1354@1|root,COG1354@2|Bacteria,2NPM8@2323|unclassified Bacteria	2|Bacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
FNPCBABE_01390	1120746.CCNL01000011_gene1689	4.41e-69	216.0	COG1386@1|root,COG1386@2|Bacteria,2NPPM@2323|unclassified Bacteria	2|Bacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
FNPCBABE_01391	428125.CLOLEP_00444	1.04e-24	103.0	2EMWG@1|root,33FIR@2|Bacteria,1VN82@1239|Firmicutes,24UV8@186801|Clostridia,3WR68@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2953)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
FNPCBABE_01392	428125.CLOLEP_00443	6.11e-47	156.0	COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,24JJ5@186801|Clostridia,3WJU2@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YtfJ	ytfJ	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
FNPCBABE_01393	428125.CLOLEP_00442	3.53e-100	308.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WGET@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
FNPCBABE_01394	1514668.JOOA01000002_gene3224	1.07e-94	285.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,3WHAC@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
FNPCBABE_01395	1120746.CCNL01000011_gene1695	4.16e-117	357.0	COG4799@1|root,COG4799@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	mdcD	-	2.1.3.10,4.1.1.87	ko:K13932,ko:K13933,ko:K20510,ko:K20511	-	-	-	-	ko00000,ko01000,ko02000	3.B.1.1.4	-	-	Carboxyl_trans,MdcE
FNPCBABE_01396	237368.SCABRO_01762	0.000279	47.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,2J0WT@203682|Planctomycetes	203682|Planctomycetes	C	Conserved carboxylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
FNPCBABE_01397	428125.CLOLEP_00436	1.39e-277	766.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate carboxylase, C-terminal domain subunit K01960	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
FNPCBABE_01399	877414.ATWA01000007_gene201	7.4e-34	148.0	COG4733@1|root,COG4733@2|Bacteria,1VU1V@1239|Firmicutes,24Y5S@186801|Clostridia,26CE8@186813|unclassified Clostridiales	2|Bacteria	G	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_48,Peptidase_M43,fn3
FNPCBABE_01400	411490.ANACAC_01419	4.9e-221	612.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
FNPCBABE_01401	428125.CLOLEP_00059	1.43e-71	219.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,3WJ0F@541000|Ruminococcaceae	186801|Clostridia	E	Acetolactate synthase small	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
FNPCBABE_01402	428125.CLOLEP_00060	3.99e-279	776.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3WHFZ@541000|Ruminococcaceae	186801|Clostridia	H	acetolactate synthase large subunit	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
FNPCBABE_01404	1121334.KB911073_gene1924	2.77e-65	202.0	COG3773@1|root,COG3773@2|Bacteria,1V4KW@1239|Firmicutes,24GK5@186801|Clostridia,3WJ6D@541000|Ruminococcaceae	186801|Clostridia	M	cell wall hydrolase	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2
FNPCBABE_01405	428125.CLOLEP_03844	4.27e-27	109.0	2E8BQ@1|root,332QD@2|Bacteria,1VH5U@1239|Firmicutes,24R1P@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01407	1519439.JPJG01000058_gene2064	3.21e-98	303.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,2N6V9@216572|Oscillospiraceae	186801|Clostridia	H	HemN C-terminal domain	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
FNPCBABE_01408	1105031.HMPREF1141_1128	6.15e-296	817.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,36DUQ@31979|Clostridiaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
FNPCBABE_01409	1449050.JNLE01000003_gene340	8.33e-110	340.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,36DPH@31979|Clostridiaceae	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
FNPCBABE_01410	97138.C820_02724	1.28e-10	57.0	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,36N0I@31979|Clostridiaceae	186801|Clostridia	S	Six-cysteine peptide SCIFF	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
FNPCBABE_01411	411483.FAEPRAA2165_01520	2.71e-278	768.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,3WGAH@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
FNPCBABE_01412	1268240.ATFI01000013_gene1110	3.79e-109	323.0	COG1234@1|root,COG1234@2|Bacteria,4NH9K@976|Bacteroidetes,2FP6X@200643|Bacteroidia,4AP3W@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
FNPCBABE_01413	445972.ANACOL_03047	7.28e-210	610.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WH9H@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB2	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
FNPCBABE_01414	1232446.BAIE02000048_gene178	7.31e-12	62.4	COG1918@1|root,COG1918@2|Bacteria,1VK8Z@1239|Firmicutes	1239|Firmicutes	P	Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
FNPCBABE_01415	1499689.CCNN01000011_gene2957	2.39e-79	277.0	COG1657@1|root,COG5492@1|root,COG1657@2|Bacteria,COG5492@2|Bacteria,1UZVS@1239|Firmicutes,24DV2@186801|Clostridia,36ESQ@31979|Clostridiaceae	186801|Clostridia	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,Prenyltrans,SLH,SQHop_cyclase_C
FNPCBABE_01416	1121289.JHVL01000037_gene3042	1.76e-76	241.0	COG1657@1|root,COG1657@2|Bacteria,1VBUR@1239|Firmicutes,24F29@186801|Clostridia,36HXY@31979|Clostridiaceae	186801|Clostridia	I	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
FNPCBABE_01417	138119.DSY3852	2.35e-107	321.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,2616E@186807|Peptococcaceae	186801|Clostridia	P	PFAM Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
FNPCBABE_01418	138119.DSY3851	0.0	952.0	COG1129@1|root,COG4720@1|root,COG1129@2|Bacteria,COG4720@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,267B9@186807|Peptococcaceae	186801|Clostridia	G	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF-ribofla_trS,ECF_trnsprt
FNPCBABE_01419	411474.COPEUT_02205	9.87e-308	843.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF_1	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
FNPCBABE_01420	1203606.HMPREF1526_02111	3.73e-161	456.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,36DNY@31979|Clostridiaceae	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
FNPCBABE_01421	1120746.CCNL01000011_gene1801	3.2e-71	235.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
FNPCBABE_01423	1514668.JOOA01000002_gene1723	1.58e-192	541.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3WGWV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
FNPCBABE_01424	1280694.AUJQ01000005_gene1380	0.0	1081.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,3NGHV@46205|Pseudobutyrivibrio	186801|Clostridia	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
FNPCBABE_01425	445972.ANACOL_03424	9.22e-36	122.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,3WJXE@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
FNPCBABE_01426	1120746.CCNL01000011_gene1810	8.58e-36	124.0	2DG94@1|root,337GI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01427	553184.ATORI0001_0085	3.32e-29	107.0	COG3041@1|root,COG3041@2|Bacteria,2GT66@201174|Actinobacteria,4CYIY@84998|Coriobacteriia	84998|Coriobacteriia	S	addiction module toxin, RelE StbE family	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
FNPCBABE_01428	1321782.HMPREF1986_01587	4.72e-20	84.3	COG3077@1|root,COG3077@2|Bacteria,1VDWV@1239|Firmicutes,24T0S@186801|Clostridia	186801|Clostridia	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
FNPCBABE_01429	478749.BRYFOR_08890	0.0	1097.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
FNPCBABE_01430	411462.DORLON_02320	9.92e-47	152.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,27VQM@189330|Dorea	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
FNPCBABE_01431	457412.RSAG_02439	2.61e-49	157.0	COG3041@1|root,COG3041@2|Bacteria,1TUTV@1239|Firmicutes,25NAT@186801|Clostridia,3WQD7@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial toxin of type II toxin-antitoxin system, YafQ	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
FNPCBABE_01432	457412.RSAG_02440	5.4e-48	154.0	COG3077@1|root,COG3077@2|Bacteria,1VABY@1239|Firmicutes,24PQZ@186801|Clostridia,3WKWU@541000|Ruminococcaceae	186801|Clostridia	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
FNPCBABE_01433	1120746.CCNL01000010_gene1362	1.23e-36	125.0	COG0238@1|root,COG0238@2|Bacteria,2NQ53@2323|unclassified Bacteria	2|Bacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
FNPCBABE_01434	713605.ADHG01000001_gene405	2.12e-29	112.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,3F66N@33958|Lactobacillaceae	91061|Bacilli	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
FNPCBABE_01435	428125.CLOLEP_00519	2.95e-42	140.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3WK85@541000|Ruminococcaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
FNPCBABE_01436	246199.CUS_7705	4.35e-70	219.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,3WM7Q@541000|Ruminococcaceae	186801|Clostridia	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
FNPCBABE_01437	1410674.JNKU01000024_gene1981	4.14e-154	440.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,3F4VD@33958|Lactobacillaceae	91061|Bacilli	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
FNPCBABE_01438	1160721.RBI_I00452	2.78e-246	684.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WGNF@541000|Ruminococcaceae	186801|Clostridia	E	O-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
FNPCBABE_01439	246199.CUS_8114	1.8e-59	187.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3WJN5@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
FNPCBABE_01440	665956.HMPREF1032_01860	5.12e-174	503.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,3WP2F@541000|Ruminococcaceae	186801|Clostridia	S	Permease family	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
FNPCBABE_01441	445972.ANACOL_00781	1.07e-87	266.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia,3WG7B@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
FNPCBABE_01444	476272.RUMHYD_02454	1.45e-143	407.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,3XYW9@572511|Blautia	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
FNPCBABE_01445	445972.ANACOL_02977	4.03e-55	183.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,3WJ3Y@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	HHH,RadC
FNPCBABE_01446	428125.CLOLEP_03191	0.0	1040.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,3WGH5@541000|Ruminococcaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
FNPCBABE_01447	428125.CLOLEP_02601	0.0	1044.0	COG0187@1|root,COG0187@2|Bacteria,1TQ6U@1239|Firmicutes,249NI@186801|Clostridia,3WH8Y@541000|Ruminococcaceae	186801|Clostridia	L	DNA topoisomerase	-	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
FNPCBABE_01448	428125.CLOLEP_02604	0.0	1094.0	COG0188@1|root,COG0188@2|Bacteria,1TPPU@1239|Firmicutes,24CU3@186801|Clostridia,3WG8X@541000|Ruminococcaceae	186801|Clostridia	L	PFAM DNA gyrase topoisomerase IV, subunit A	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
FNPCBABE_01449	1105031.HMPREF1141_0303	7.81e-22	87.8	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
FNPCBABE_01450	1120746.CCNL01000013_gene2015	7.72e-09	55.1	2FBQ5@1|root,343V3@2|Bacteria	2|Bacteria	S	SigmaK-factor processing regulatory protein BofA	-	-	-	-	-	-	-	-	-	-	-	-	BofA
FNPCBABE_01451	1121334.KB911071_gene2074	1.19e-42	149.0	COG3432@1|root,COG3432@2|Bacteria,1VDQ8@1239|Firmicutes,24R9Q@186801|Clostridia,3WK5T@541000|Ruminococcaceae	186801|Clostridia	K	Domain of unknown function (DUF4364)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
FNPCBABE_01452	445975.COLSTE_02427	4.49e-43	146.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4CW6P@84998|Coriobacteriia	84998|Coriobacteriia	K	transcriptional regulator, Rrf2 family	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
FNPCBABE_01453	887929.HMP0721_1836	3.27e-125	362.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,2489I@186801|Clostridia,25VGE@186806|Eubacteriaceae	186801|Clostridia	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
FNPCBABE_01454	411489.CLOL250_02466	2.04e-296	813.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,36G21@31979|Clostridiaceae	186801|Clostridia	O	FeS assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
FNPCBABE_01455	626939.HMPREF9443_01188	4.57e-91	284.0	COG0719@1|root,COG0719@2|Bacteria,1TRQJ@1239|Firmicutes,4H43G@909932|Negativicutes	909932|Negativicutes	O	SufB sufD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UPF0051
FNPCBABE_01456	742733.HMPREF9469_05810	1.54e-199	563.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,21Z26@1506553|Lachnoclostridium	186801|Clostridia	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
FNPCBABE_01457	1408436.JHXY01000010_gene886	2.92e-67	207.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,25WT8@186806|Eubacteriaceae	186801|Clostridia	C	SUF system FeS assembly protein, NifU family	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
FNPCBABE_01459	1235799.C818_02530	2.9e-239	667.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,27J6E@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
FNPCBABE_01460	1235793.C809_00466	0.0	948.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,27J01@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha amylase, catalytic domain	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
FNPCBABE_01461	537013.CLOSTMETH_00841	1.55e-218	624.0	COG0366@1|root,COG4728@1|root,COG0366@2|Bacteria,COG4728@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia,3WGMX@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain protein	-	-	3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R10223,R11262	RC00477	ko00000,ko00001,ko01000,ko03016	-	GH13	-	Alpha-amylase,Alpha-amylase_C,DUF1653,Malt_amylase_C
FNPCBABE_01465	411473.RUMCAL_00965	7.42e-60	190.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,3WIS5@541000|Ruminococcaceae	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
FNPCBABE_01466	1203606.HMPREF1526_00607	5.32e-46	157.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,36IEQ@31979|Clostridiaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
FNPCBABE_01467	428125.CLOLEP_02989	2.52e-199	558.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,3WGXE@541000|Ruminococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
FNPCBABE_01468	428125.CLOLEP_02990	1.73e-213	602.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3WGDW@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
FNPCBABE_01469	1120746.CCNL01000008_gene588	5.32e-171	481.0	COG1092@1|root,COG1092@2|Bacteria	2|Bacteria	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
FNPCBABE_01470	428125.CLOLEP_02992	4.65e-140	402.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WG9K@541000|Ruminococcaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
FNPCBABE_01471	428125.CLOLEP_02993	1.89e-135	391.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WG8V@541000|Ruminococcaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	cbiO	-	-	ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
FNPCBABE_01472	1120746.CCNL01000008_gene591	1.22e-100	301.0	COG0619@1|root,COG0619@2|Bacteria	2|Bacteria	P	transmembrane transporter activity	ecfT	-	-	ko:K16783,ko:K16785	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
FNPCBABE_01473	428125.CLOLEP_02995	3.85e-125	363.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,3WIKF@541000|Ruminococcaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
FNPCBABE_01475	411474.COPEUT_00066	5.88e-164	459.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia	186801|Clostridia	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
FNPCBABE_01476	411474.COPEUT_00067	0.0	1234.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD
FNPCBABE_01477	411474.COPEUT_00068	1.21e-44	145.0	2FJ5Y@1|root,34AW2@2|Bacteria,1W1C4@1239|Firmicutes,253GU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01478	411474.COPEUT_00069	2.68e-142	402.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia	186801|Clostridia	P	domain protein	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
FNPCBABE_01479	411474.COPEUT_00070	4.82e-281	773.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia	186801|Clostridia	P	Potassium uptake protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
FNPCBABE_01480	1280694.AUJQ01000014_gene1156	2.91e-91	271.0	COG0406@1|root,COG0406@2|Bacteria,1V25J@1239|Firmicutes,24FZT@186801|Clostridia,3NGMI@46205|Pseudobutyrivibrio	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
FNPCBABE_01481	1392493.JIAB01000001_gene1643	9.77e-85	253.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24HQM@186801|Clostridia,27MPZ@186928|unclassified Lachnospiraceae	186801|Clostridia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
FNPCBABE_01482	1035197.HMPREF9999_02353	2.88e-25	110.0	COG3680@1|root,COG3680@2|Bacteria,4NJA4@976|Bacteroidetes	976|Bacteroidetes	O	regulation of methylation-dependent chromatin silencing	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01483	1160721.RBI_II00420	1.02e-269	768.0	COG1961@1|root,COG2002@1|root,COG1961@2|Bacteria,COG2002@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3WI42@541000|Ruminococcaceae	186801|Clostridia	KL	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,SpoVT_C,Zn_ribbon_recom
FNPCBABE_01485	1321372.AQQB01000003_gene1497	7.01e-31	112.0	2CDK1@1|root,32G0D@2|Bacteria,1V6YH@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MobC
FNPCBABE_01486	243275.TDE_0496	2.94e-29	105.0	COG1396@1|root,COG1396@2|Bacteria,2J8UK@203691|Spirochaetes	203691|Spirochaetes	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
FNPCBABE_01487	553177.CAPSP0001_1735	2.24e-35	124.0	COG3550@1|root,COG3550@2|Bacteria,4NTCR@976|Bacteroidetes,1I43U@117743|Flavobacteriia,1ESH9@1016|Capnocytophaga	976|Bacteroidetes	S	HipA N-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA
FNPCBABE_01488	221027.JO40_03155	5.17e-144	415.0	COG3550@1|root,COG3550@2|Bacteria,2J6CS@203691|Spirochaetes	203691|Spirochaetes	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	HipA_C
FNPCBABE_01489	483218.BACPEC_01747	0.0	1033.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,267SN@186813|unclassified Clostridiales	186801|Clostridia	V	type I restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	HsdM_N,N6_Mtase
FNPCBABE_01491	1235835.C814_00054	3.11e-144	442.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,3WHFQ@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the V-ATPase 116 kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
FNPCBABE_01492	1151292.QEW_3577	5.39e-38	134.0	COG0636@1|root,COG0636@2|Bacteria,1V786@1239|Firmicutes,24HBF@186801|Clostridia,25TT6@186804|Peptostreptococcaceae	186801|Clostridia	C	ATP synthase subunit C	ntpK	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
FNPCBABE_01495	1232443.BAIA02000097_gene3411	1.72e-31	114.0	COG1436@1|root,COG1436@2|Bacteria,1VAX7@1239|Firmicutes,24MXC@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
FNPCBABE_01496	641112.ACOK01000082_gene3311	7.76e-316	873.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,3WGBK@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
FNPCBABE_01497	1232443.BAIA02000097_gene3413	1.52e-288	793.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,267RU@186813|unclassified Clostridiales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
FNPCBABE_01498	457421.CBFG_04902	1.54e-92	277.0	COG1394@1|root,COG1394@2|Bacteria,1TQ1Y@1239|Firmicutes,247TC@186801|Clostridia,268C8@186813|unclassified Clostridiales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
FNPCBABE_01503	97139.C824_00384	0.0	947.0	COG2015@1|root,COG2015@2|Bacteria,1TR7Q@1239|Firmicutes,248SN@186801|Clostridia,36K01@31979|Clostridiaceae	186801|Clostridia	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
FNPCBABE_01504	478749.BRYFOR_09129	8.22e-77	239.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24DB9@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
FNPCBABE_01505	478749.BRYFOR_09130	8.28e-141	417.0	COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
FNPCBABE_01506	903814.ELI_0510	4.13e-146	424.0	COG3049@1|root,COG3049@2|Bacteria,1TRTI@1239|Firmicutes,24AFG@186801|Clostridia,25X6F@186806|Eubacteriaceae	186801|Clostridia	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT,CBAH
FNPCBABE_01507	411473.RUMCAL_00834	2.55e-230	637.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
FNPCBABE_01508	1211844.CBLM010000055_gene429	4.02e-40	140.0	COG1329@1|root,COG1329@2|Bacteria,1V7IF@1239|Firmicutes,3VRZS@526524|Erysipelotrichia	526524|Erysipelotrichia	K	CarD-like/TRCF domain	-	-	-	-	-	-	-	-	-	-	-	-	CarD_CdnL_TRCF
FNPCBABE_01509	573061.Clocel_0310	0.000776	51.6	COG3055@1|root,COG5492@1|root,COG3055@2|Bacteria,COG5492@2|Bacteria,1V5WF@1239|Firmicutes,24H47@186801|Clostridia,36IV6@31979|Clostridiaceae	186801|Clostridia	N	PFAM Kelch	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1
FNPCBABE_01510	552398.HMPREF0866_02539	1.11e-129	386.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia,3WG7U@541000|Ruminococcaceae	186801|Clostridia	G	Hydrolase Family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
FNPCBABE_01511	97139.C824_03631	1.26e-64	201.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,24HPW@186801|Clostridia,36J4K@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
FNPCBABE_01512	1410628.JNKS01000019_gene1298	2.46e-83	254.0	COG0652@1|root,COG0652@2|Bacteria,1V1SP@1239|Firmicutes,24G4H@186801|Clostridia,27MJD@186928|unclassified Lachnospiraceae	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
FNPCBABE_01513	411467.BACCAP_01604	1.52e-90	277.0	COG1682@1|root,COG1682@2|Bacteria,1UY8J@1239|Firmicutes,24CN9@186801|Clostridia,26ACB@186813|unclassified Clostridiales	186801|Clostridia	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
FNPCBABE_01514	1280696.ATVY01000002_gene3515	5.94e-129	385.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,4BYR2@830|Butyrivibrio	186801|Clostridia	GM	ATPases associated with a variety of cellular activities	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
FNPCBABE_01515	428125.CLOLEP_01588	1.06e-84	256.0	COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,1TQ50@1239|Firmicutes,249IF@186801|Clostridia,3WIH3@541000|Ruminococcaceae	186801|Clostridia	MT	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3,SPOR
FNPCBABE_01516	755731.Clo1100_3749	6.17e-77	238.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,36FNS@31979|Clostridiaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
FNPCBABE_01518	1120746.CCNL01000011_gene1609	1.91e-155	454.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,2NPE2@2323|unclassified Bacteria	2|Bacteria	J	N-terminal domain of 16S rRNA methyltransferase RsmF	rsmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176,2.1.1.178	ko:K03500,ko:K11392	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
FNPCBABE_01519	1235835.C814_02088	2.11e-124	363.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3WGWE@541000|Ruminococcaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
FNPCBABE_01521	610130.Closa_3038	0.0	1136.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,21XE0@1506553|Lachnoclostridium	186801|Clostridia	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
FNPCBABE_01522	397288.C806_00777	1.3e-13	78.2	COG0860@1|root,COG1705@1|root,COG5632@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,COG5632@2|Bacteria,1V7JY@1239|Firmicutes,24C0T@186801|Clostridia,27M0W@186928|unclassified Lachnospiraceae	186801|Clostridia	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Amidase_3,CW_7,CW_binding_1,Cu_amine_oxidN1,Glucosaminidase,PG_binding_1
FNPCBABE_01524	633147.Olsu_1195	5.78e-06	47.4	2B2D6@1|root,31UXQ@2|Bacteria,2HWBK@201174|Actinobacteria,4CY7Q@84998|Coriobacteriia	84998|Coriobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01525	1120746.CCNL01000011_gene1768	0.0	1465.0	COG0178@1|root,COG0178@2|Bacteria,2NNT3@2323|unclassified Bacteria	2|Bacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
FNPCBABE_01526	1121334.KB911071_gene2085	4.42e-274	773.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3WG86@541000|Ruminococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
FNPCBABE_01527	386415.NT01CX_1039	1.17e-65	206.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,36HYM@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
FNPCBABE_01528	1158318.ATXC01000002_gene1468	5.01e-62	214.0	COG0037@1|root,COG0037@2|Bacteria,2G41C@200783|Aquificae	200783|Aquificae	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
FNPCBABE_01529	428125.CLOLEP_02597	1.53e-210	595.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WH8B@541000|Ruminococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
FNPCBABE_01530	428125.CLOLEP_02596	1.8e-64	200.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,3WJCC@541000|Ruminococcaceae	186801|Clostridia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
FNPCBABE_01531	1105031.HMPREF1141_0312	8.38e-182	538.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,36E60@31979|Clostridiaceae	186801|Clostridia	T	domain protein	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
FNPCBABE_01532	428125.CLOLEP_02592	1.53e-300	841.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3WH9M@541000|Ruminococcaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
FNPCBABE_01533	428125.CLOLEP_03333	7.53e-71	216.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3WJA1@541000|Ruminococcaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
FNPCBABE_01534	1105031.HMPREF1141_2858	7.83e-65	208.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,36EHE@31979|Clostridiaceae	186801|Clostridia	O	Glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
FNPCBABE_01535	1120746.CCNL01000013_gene1976	1.92e-60	189.0	COG0802@1|root,COG0802@2|Bacteria,2NPU4@2323|unclassified Bacteria	2|Bacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	2.7.1.221	ko:K06925,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	TsaE
FNPCBABE_01536	428125.CLOLEP_03336	3.01e-312	861.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
FNPCBABE_01537	428125.CLOLEP_03338	9.27e-115	347.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,3WJ15@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
FNPCBABE_01539	411483.FAEPRAA2165_01954	2.95e-63	208.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,3WGY9@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
FNPCBABE_01540	428125.CLOLEP_03096	1.86e-134	396.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,3WH06@541000|Ruminococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
FNPCBABE_01542	428125.CLOLEP_03141	1.88e-105	312.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,3WH3Y@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
FNPCBABE_01543	1120746.CCNL01000011_gene1753	3.5e-128	374.0	COG0329@1|root,COG0329@2|Bacteria,2NP5Q@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1521	DHDPS
FNPCBABE_01544	428125.CLOLEP_03139	6.12e-202	565.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3WGVU@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
FNPCBABE_01545	246199.CUS_6206	4.69e-179	506.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3WGMR@541000|Ruminococcaceae	186801|Clostridia	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
FNPCBABE_01546	1120746.CCNL01000011_gene1750	2.36e-214	598.0	COG0343@1|root,COG0343@2|Bacteria,2NNQS@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
FNPCBABE_01547	428125.CLOLEP_03125	1.46e-15	75.1	COG1862@1|root,COG1862@2|Bacteria	2|Bacteria	U	protein transport	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
FNPCBABE_01549	515620.EUBELI_00888	6.08e-70	215.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,24HSW@186801|Clostridia,25WA3@186806|Eubacteriaceae	186801|Clostridia	S	small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
FNPCBABE_01550	86416.Clopa_4831	1.26e-89	284.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia,36EA5@31979|Clostridiaceae	186801|Clostridia	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
FNPCBABE_01551	272563.CD630_32870	3.15e-195	562.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,25QFR@186804|Peptostreptococcaceae	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
FNPCBABE_01552	873513.HMPREF6485_0820	4.5e-142	452.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM26,SLH
FNPCBABE_01553	428125.CLOLEP_02820	1.13e-212	595.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3WG9F@541000|Ruminococcaceae	186801|Clostridia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
FNPCBABE_01554	1410625.JHWK01000002_gene560	3.09e-151	449.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,27JFR@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Binding-protein-dependent transport system inner membrane component	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
FNPCBABE_01555	457421.CBFG_01643	3.39e-122	354.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,2689B@186813|unclassified Clostridiales	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
FNPCBABE_01556	537013.CLOSTMETH_01463	1.56e-126	380.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WGBR@541000|Ruminococcaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
FNPCBABE_01557	1120746.CCNL01000010_gene1377	9.88e-219	642.0	COG0474@1|root,COG0474@2|Bacteria	2|Bacteria	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
FNPCBABE_01558	1121334.KB911066_gene589	3.08e-210	592.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,3WHCB@541000|Ruminococcaceae	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18870	Orn_Arg_deC_N,Orn_DAP_Arg_deC
FNPCBABE_01559	1507.HMPREF0262_00789	2.25e-58	189.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,36EDR@31979|Clostridiaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
FNPCBABE_01560	1120746.CCNL01000011_gene1732	3.37e-302	856.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
FNPCBABE_01561	1121334.KB911066_gene586	6.42e-198	562.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WGYG@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
FNPCBABE_01562	428125.CLOLEP_02375	6.23e-107	311.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,3WGQP@541000|Ruminococcaceae	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
FNPCBABE_01563	428125.CLOLEP_02374	1.86e-159	463.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
FNPCBABE_01564	1235835.C814_00651	6.41e-91	274.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,249BN@186801|Clostridia,3WIIA@541000|Ruminococcaceae	186801|Clostridia	S	Ser Thr phosphatase family protein	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
FNPCBABE_01565	428125.CLOLEP_02372	3.04e-229	646.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3WGWF@541000|Ruminococcaceae	186801|Clostridia	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
FNPCBABE_01566	1378168.N510_03492	1.75e-51	180.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes	1239|Firmicutes	E	Dipeptidase	dp2	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
FNPCBABE_01567	272562.CA_C1763	2.54e-20	86.7	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,36MV2@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
FNPCBABE_01568	1507.HMPREF0262_00800	1.99e-69	217.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,36DHX@31979|Clostridiaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
FNPCBABE_01569	428125.CLOLEP_02368	3.3e-143	411.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,3WGB7@541000|Ruminococcaceae	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
FNPCBABE_01570	877411.JMMA01000002_gene1335	3.08e-33	123.0	COG0681@1|root,COG0681@2|Bacteria,1V6R3@1239|Firmicutes,25CN6@186801|Clostridia,3WKCK@541000|Ruminococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
FNPCBABE_01571	626939.HMPREF9443_00821	1.09e-69	217.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4H42H@909932|Negativicutes	909932|Negativicutes	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
FNPCBABE_01572	428125.CLOLEP_02052	8.55e-195	560.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,3WGAA@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
FNPCBABE_01573	1105031.HMPREF1141_0022	6.12e-137	405.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,36ES8@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,5.1.1.18	ko:K01775,ko:K18348	ko00473,ko01100,ko01502,ko02020,map00473,map01100,map01502,map02020	M00652	R00401	RC00285	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	-	-	-	Acyl_transf_3,Ala_racemase_C,Ala_racemase_N
FNPCBABE_01574	428125.CLOLEP_03726	0.0	988.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WGRT@541000|Ruminococcaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
FNPCBABE_01575	663278.Ethha_2634	1.22e-26	104.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,3WSE6@541000|Ruminococcaceae	186801|Clostridia	T	Low molecular weight phosphatase family	-	-	3.1.3.48,5.3.1.6	ko:K01104,ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LMWPc,LacAB_rpiB
FNPCBABE_01576	1235835.C814_00269	3.78e-40	139.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3WKHF@541000|Ruminococcaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
FNPCBABE_01577	1120746.CCNL01000004_gene59	2.76e-179	506.0	COG0533@1|root,COG0533@2|Bacteria,2NNXP@2323|unclassified Bacteria	2|Bacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	R10648	RC00070,RC00416	ko00000,ko00001,ko00002,ko01000,ko02044,ko03016	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Peptidase_M22
FNPCBABE_01578	1336241.JAEB01000005_gene1429	1.02e-101	296.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,25W2U@186806|Eubacteriaceae	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
FNPCBABE_01579	1410670.JHXF01000020_gene2216	6.68e-172	488.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,3WGSG@541000|Ruminococcaceae	186801|Clostridia	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
FNPCBABE_01582	180332.JTGN01000001_gene5260	2.91e-188	539.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
FNPCBABE_01587	1514668.JOOA01000002_gene2989	0.0	1053.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3WGVM@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
FNPCBABE_01589	1235797.C816_00840	6.21e-39	129.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,2N7PC@216572|Oscillospiraceae	186801|Clostridia	J	Ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
FNPCBABE_01590	1121334.KB911066_gene1113	2.81e-74	230.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,3WIHN@541000|Ruminococcaceae	186801|Clostridia	S	YigZ family	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
FNPCBABE_01591	537013.CLOSTMETH_02105	3.53e-168	499.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3WGFW@541000|Ruminococcaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
FNPCBABE_01592	428125.CLOLEP_03935	1.09e-203	570.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WGMV@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
FNPCBABE_01593	742738.HMPREF9460_00778	6.86e-22	90.9	COG3824@1|root,COG3824@2|Bacteria,1VFAZ@1239|Firmicutes,24RK0@186801|Clostridia,2693S@186813|unclassified Clostridiales	186801|Clostridia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Maf,Zincin_1
FNPCBABE_01594	673839.D2J077_9CAUD	2.07e-07	55.1	4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses  no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae	10699|Siphoviridae	S	peptidoglycan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01595	457421.CBFG_01177	1.57e-180	516.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,268GV@186813|unclassified Clostridiales	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
FNPCBABE_01598	1120998.AUFC01000008_gene1121	1.04e-136	412.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
FNPCBABE_01599	1410631.JHWZ01000005_gene231	5.73e-70	223.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,27IS7@186928|unclassified Lachnospiraceae	186801|Clostridia	O	prohibitin homologues	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
FNPCBABE_01600	1235800.C819_01113	2.96e-77	256.0	COG4905@1|root,COG4905@2|Bacteria,1TQUM@1239|Firmicutes,25CKD@186801|Clostridia,27J1N@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
FNPCBABE_01601	1384065.JAGS01000001_gene2814	3.56e-74	226.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3WITM@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
FNPCBABE_01602	1160721.RBI_II00080	1.5e-166	485.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3WH6T@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
FNPCBABE_01603	428125.CLOLEP_02078	8.61e-185	521.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,3WHKH@541000|Ruminococcaceae	186801|Clostridia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
FNPCBABE_01604	1120746.CCNL01000011_gene1814	4.52e-94	280.0	COG0299@1|root,COG0299@2|Bacteria,2NPFD@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2,6.3.2.6,6.3.4.13	ko:K11175,ko:K13713	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04144,R04325,R04326,R04591	RC00026,RC00064,RC00090,RC00162,RC00166,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N,YjbR
FNPCBABE_01605	1160721.RBI_II00077	4.78e-129	371.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3WGGF@541000|Ruminococcaceae	186801|Clostridia	F	IMP cyclohydrolase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
FNPCBABE_01606	1122931.AUAE01000009_gene4706	2.72e-238	660.0	COG0138@1|root,COG0138@2|Bacteria,4NIY8@976|Bacteroidetes,2FMYP@200643|Bacteroidia	976|Bacteroidetes	F	AICARFT IMPCHase bienzyme	purH2	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
FNPCBABE_01607	1120746.CCNL01000011_gene1811	3.12e-225	629.0	COG0151@1|root,COG0151@2|Bacteria,2NP0B@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the GARS family	purD	-	6.3.2.6,6.3.4.13	ko:K01945,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
FNPCBABE_01608	428125.CLOLEP_03274	1.21e-108	321.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia,3WGU4@541000|Ruminococcaceae	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
FNPCBABE_01609	509191.AEDB02000109_gene5077	1.76e-55	189.0	COG0750@1|root,COG0750@2|Bacteria,1TPIR@1239|Firmicutes,24AFA@186801|Clostridia,3WHID@541000|Ruminococcaceae	186801|Clostridia	M	Stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
FNPCBABE_01610	927704.SELR_04440	1.3e-70	216.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
FNPCBABE_01611	1219080.VEZ01S_07_00030	2e-33	127.0	COG3183@1|root,COG3183@2|Bacteria,1MZRA@1224|Proteobacteria,1SA0W@1236|Gammaproteobacteria,1XYI8@135623|Vibrionales	135623|Vibrionales	V	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
FNPCBABE_01612	411473.RUMCAL_02661	0.0	925.0	COG1196@1|root,COG1196@2|Bacteria,1VEQ8@1239|Firmicutes,24S20@186801|Clostridia	186801|Clostridia	L	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
FNPCBABE_01613	397290.C810_00457	0.0	1702.0	COG1002@1|root,COG1002@2|Bacteria,1U23X@1239|Firmicutes,25J2T@186801|Clostridia,27T5E@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01614	428125.CLOLEP_03218	3.57e-81	241.0	2C5R4@1|root,31VPY@2|Bacteria,1V8EP@1239|Firmicutes,24JPJ@186801|Clostridia,3WJKA@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
FNPCBABE_01615	428125.CLOLEP_03219	2.98e-268	735.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,3WHRE@541000|Ruminococcaceae	186801|Clostridia	M	plasmid recombination	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
FNPCBABE_01616	411460.RUMTOR_02162	1.32e-188	533.0	COG3598@1|root,COG3598@2|Bacteria,1TU5N@1239|Firmicutes,247KK@186801|Clostridia,3Y28V@572511|Blautia	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,PriCT_1,Prim-Pol
FNPCBABE_01617	1519439.JPJG01000056_gene2250	1.11e-49	160.0	2AQJ5@1|root,31FRY@2|Bacteria,1V6TG@1239|Firmicutes,24JD1@186801|Clostridia,2N8GP@216572|Oscillospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01618	428125.CLOLEP_03222	1.37e-247	681.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WHJS@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
FNPCBABE_01619	428125.CLOLEP_03223	3.84e-32	112.0	2E5UB@1|root,331IU@2|Bacteria,1VH5Y@1239|Firmicutes,24S88@186801|Clostridia,3WKFA@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mga
FNPCBABE_01620	545697.HMPREF0216_02278	2.89e-67	212.0	COG0546@1|root,COG0546@2|Bacteria,1V4W6@1239|Firmicutes,24C82@186801|Clostridia,36IKK@31979|Clostridiaceae	186801|Clostridia	S	IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
FNPCBABE_01622	1280694.AUJQ01000004_gene558	1.3e-49	166.0	COG0560@1|root,COG0560@2|Bacteria,1V8Y8@1239|Firmicutes	1239|Firmicutes	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
FNPCBABE_01623	642492.Clole_0404	7.76e-31	124.0	2A16J@1|root,30PCK@2|Bacteria,1UPNY@1239|Firmicutes,25HKA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01624	428125.CLOLEP_03188	2.2e-60	194.0	COG0484@1|root,COG0484@2|Bacteria,1V1GK@1239|Firmicutes,2494E@186801|Clostridia,3WITE@541000|Ruminococcaceae	186801|Clostridia	O	DnaJ domain protein	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,TPR_2
FNPCBABE_01625	553973.CLOHYLEM_06652	9.46e-05	49.3	2DQ8Z@1|root,335CG@2|Bacteria,1V9R5@1239|Firmicutes,24I50@186801|Clostridia,2237K@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01626	1195236.CTER_5025	1.19e-07	63.2	COG5492@1|root,COG5492@2|Bacteria,1V4A5@1239|Firmicutes,24IM0@186801|Clostridia	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
FNPCBABE_01627	428125.CLOLEP_03121	8.48e-88	269.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,3WGT7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
FNPCBABE_01629	1304880.JAGB01000002_gene1652	2.1e-07	59.7	COG5578@1|root,COG5578@2|Bacteria,1V3G3@1239|Firmicutes,24H3P@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
FNPCBABE_01632	1321778.HMPREF1982_00514	2.46e-141	406.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,268M6@186813|unclassified Clostridiales	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
FNPCBABE_01633	1232449.BAHV02000020_gene1353	1.64e-19	81.6	2E5HW@1|root,33098@2|Bacteria,1VFFD@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01634	428125.CLOLEP_00589	7.29e-176	504.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3WGV5@541000|Ruminococcaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
FNPCBABE_01635	411477.PARMER_01961	2.23e-121	357.0	COG0463@1|root,COG0463@2|Bacteria,4NGTD@976|Bacteroidetes,2FPNS@200643|Bacteroidia,22ZF2@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
FNPCBABE_01636	1131730.BAVI_17107	4.98e-111	335.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,4HC0S@91061|Bacilli,1ZEMI@1386|Bacillus	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
FNPCBABE_01637	665950.HMPREF1025_00995	7.75e-36	141.0	2BSY6@1|root,32N1Z@2|Bacteria,1U4V5@1239|Firmicutes,259JE@186801|Clostridia,27QPU@186928|unclassified Lachnospiraceae	186801|Clostridia	S	EpsG family	-	-	-	-	-	-	-	-	-	-	-	-	EpsG
FNPCBABE_01638	411462.DORLON_01605	1.63e-143	425.0	COG0438@1|root,COG2148@1|root,COG0438@2|Bacteria,COG2148@2|Bacteria,1TQX9@1239|Firmicutes,24874@186801|Clostridia,27WQN@189330|Dorea	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf
FNPCBABE_01639	742723.HMPREF9477_01866	6.43e-87	275.0	COG0438@1|root,COG2148@1|root,COG0438@2|Bacteria,COG2148@2|Bacteria,1TP49@1239|Firmicutes,249F1@186801|Clostridia,27JIX@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Bacterial sugar transferase	epsL	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf
FNPCBABE_01642	411459.RUMOBE_00569	4.79e-60	189.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,3Y08X@572511|Blautia	186801|Clostridia	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
FNPCBABE_01643	1423734.JCM14202_3512	3.55e-18	86.7	COG1309@1|root,COG1309@2|Bacteria,1V6CF@1239|Firmicutes,4HJIC@91061|Bacilli,3FCEJ@33958|Lactobacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
FNPCBABE_01644	1123075.AUDP01000014_gene2999	1.04e-289	864.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,3WGTT@541000|Ruminococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
FNPCBABE_01645	665956.HMPREF1032_02805	9.76e-65	202.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,3WIUH@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
FNPCBABE_01647	1392493.JIAB01000001_gene949	1.4e-159	451.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,27IRB@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
FNPCBABE_01648	411468.CLOSCI_03983	5.09e-105	308.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,21ZN5@1506553|Lachnoclostridium	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
FNPCBABE_01649	536232.CLM_4044	1.54e-41	147.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24FYY@186801|Clostridia,36F85@31979|Clostridiaceae	186801|Clostridia	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
FNPCBABE_01650	411461.DORFOR_02063	4.74e-147	419.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,27UR1@189330|Dorea	186801|Clostridia	H	Carbohydrate kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
FNPCBABE_01651	742765.HMPREF9457_02237	5.29e-197	556.0	COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,248EP@186801|Clostridia,27VZ9@189330|Dorea	186801|Clostridia	F	COG COG1457 Purine-cytosine permease and related proteins	cytX	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
FNPCBABE_01652	742735.HMPREF9467_03198	3.68e-258	716.0	COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,24ADD@186801|Clostridia,21ZF4@1506553|Lachnoclostridium	186801|Clostridia	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
FNPCBABE_01653	1048834.TC41_0250	4.66e-12	66.2	COG1694@1|root,COG2002@1|root,COG2002@2|Bacteria,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli	91061|Bacilli	K	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like	yabN	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
FNPCBABE_01654	428125.CLOLEP_03218	2.14e-54	173.0	2C5R4@1|root,31VPY@2|Bacteria,1V8EP@1239|Firmicutes,24JPJ@186801|Clostridia,3WJKA@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
FNPCBABE_01655	663278.Ethha_0960	0.0	945.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,1TP20@1239|Firmicutes,24BMH@186801|Clostridia,3WHBK@541000|Ruminococcaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726,DUF3320,DUF4011
FNPCBABE_01656	1280681.AUJZ01000004_gene2787	0.0	877.0	COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,1TQ81@1239|Firmicutes,259S3@186801|Clostridia,4C0IX@830|Butyrivibrio	186801|Clostridia	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
FNPCBABE_01658	428125.CLOLEP_02533	4.76e-184	552.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,3WH68@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
FNPCBABE_01659	1121334.KB911067_gene255	6.99e-51	166.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,3WJ8E@541000|Ruminococcaceae	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
FNPCBABE_01661	1160721.RBI_I00132	2.5e-24	93.6	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,252JX@186801|Clostridia,3WKI0@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
FNPCBABE_01662	428125.CLOLEP_03943	0.0	1875.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
FNPCBABE_01663	428125.CLOLEP_03941	0.0	1955.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,3WH6H@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
FNPCBABE_01664	1121115.AXVN01000092_gene77	0.0	998.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,3XYMW@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
FNPCBABE_01665	1235793.C809_01817	7.07e-69	212.0	COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,24MDJ@186801|Clostridia,27MDF@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
FNPCBABE_01666	411463.EUBVEN_01214	6.72e-94	277.0	COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,24HEU@186801|Clostridia,25WKB@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF436)	-	-	-	-	-	-	-	-	-	-	-	-	DUF436
FNPCBABE_01667	552396.HMPREF0863_00660	9.47e-285	819.0	COG1215@1|root,COG1887@1|root,COG1215@2|Bacteria,COG1887@2|Bacteria,1UYH3@1239|Firmicutes	1239|Firmicutes	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
FNPCBABE_01668	1392493.JIAB01000001_gene1584	1.91e-60	206.0	COG3274@1|root,COG3274@2|Bacteria,1V9EN@1239|Firmicutes,25CM5@186801|Clostridia,27U5U@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
FNPCBABE_01669	1069534.LRC_19370	3.55e-32	121.0	COG0454@1|root,COG0456@2|Bacteria,1VEW7@1239|Firmicutes,4HPE4@91061|Bacilli,3FBRU@33958|Lactobacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
FNPCBABE_01670	1211844.CBLM010000110_gene3478	2.6e-85	276.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,3VNYJ@526524|Erysipelotrichia	526524|Erysipelotrichia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
FNPCBABE_01671	5888.CAK75268	1.17e-06	60.8	KOG0032@1|root,KOG0032@2759|Eukaryota	2759|Eukaryota	T	protein serine/threonine kinase activity	-	GO:0000075,GO:0000077,GO:0000278,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007030,GO:0007049,GO:0007093,GO:0007095,GO:0007154,GO:0007165,GO:0007346,GO:0008150,GO:0008152,GO:0008361,GO:0009987,GO:0010256,GO:0010389,GO:0010564,GO:0010948,GO:0010972,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019538,GO:0022402,GO:0023052,GO:0031570,GO:0031572,GO:0032535,GO:0033554,GO:0035556,GO:0036211,GO:0042770,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0044773,GO:0044774,GO:0044818,GO:0045786,GO:0045792,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051726,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0072395,GO:0072401,GO:0072413,GO:0072422,GO:0090066,GO:0140096,GO:1901564,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902402,GO:1902403,GO:1902749,GO:1902750,GO:1903047	2.7.11.1	ko:K08269,ko:K13412	ko04136,ko04138,ko04139,ko04140,ko04150,ko04212,ko04626,ko05145,map04136,map04138,map04139,map04140,map04150,map04212,map04626,map05145	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03029,ko04131	-	-	-	DCX,EF-hand_1,EF-hand_5,EF-hand_7,Pkinase
FNPCBABE_01674	665956.HMPREF1032_02548	1.08e-32	125.0	COG1373@1|root,COG1373@2|Bacteria,1TPFF@1239|Firmicutes,24A52@186801|Clostridia,3WH6C@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
FNPCBABE_01675	1200567.JNKD01000042_gene973	4.49e-22	94.7	COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,1RN1I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
FNPCBABE_01677	520709.F985_01018	2.25e-11	66.6	COG5527@1|root,COG5527@2|Bacteria,1R7A6@1224|Proteobacteria,1RQMU@1236|Gammaproteobacteria,3NMCS@468|Moraxellaceae	1236|Gammaproteobacteria	L	Initiator Replication protein	repA	-	-	-	-	-	-	-	-	-	-	-	Rep_3
FNPCBABE_01678	471875.RUMLAC_01556	3.11e-30	108.0	COG4456@1|root,COG4456@2|Bacteria,1VGGR@1239|Firmicutes,2536S@186801|Clostridia,3WQKK@541000|Ruminococcaceae	186801|Clostridia	S	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
FNPCBABE_01679	471875.RUMLAC_01555	3.84e-68	208.0	COG1487@1|root,COG1487@2|Bacteria,1VCFS@1239|Firmicutes,24WCU@186801|Clostridia,3WJY2@541000|Ruminococcaceae	186801|Clostridia	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
FNPCBABE_01680	742740.HMPREF9474_01719	8.95e-122	360.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia,21XS8@1506553|Lachnoclostridium	186801|Clostridia	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
FNPCBABE_01681	927658.AJUM01000034_gene378	7.58e-62	207.0	COG2148@1|root,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,2FNC2@200643|Bacteroidia,3XIYM@558415|Marinilabiliaceae	976|Bacteroidetes	M	CoA-binding domain	-	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf,CoA_binding_3
FNPCBABE_01682	420246.GTNG_3268	8.8e-35	131.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,1WETZ@129337|Geobacillus	91061|Bacilli	D	Cellulose biosynthesis protein BcsQ	ywqD	-	2.7.10.2	ko:K00903	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,ParA
FNPCBABE_01683	246199.CUS_8055	4.05e-26	109.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,3WJVW@541000|Ruminococcaceae	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
FNPCBABE_01684	632245.CLP_2136	5.31e-25	99.8	COG2172@1|root,COG2172@2|Bacteria,1VGIQ@1239|Firmicutes,25DQ1@186801|Clostridia	186801|Clostridia	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
FNPCBABE_01685	1280664.AUIX01000037_gene2627	7.18e-23	91.7	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24NE7@186801|Clostridia,4BZWP@830|Butyrivibrio	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
FNPCBABE_01686	386456.JQKN01000009_gene1214	4.24e-100	322.0	COG0534@1|root,COG2172@1|root,arCOG01732@2157|Archaea,arCOG06892@2157|Archaea,2XVF5@28890|Euryarchaeota,23PHB@183925|Methanobacteria	183925|Methanobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
FNPCBABE_01687	97139.C824_00379	0.0	2187.0	COG1020@1|root,COG3320@1|root,COG1020@2|Bacteria,COG3320@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	6.1.1.13	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding
FNPCBABE_01688	1384057.CD33_13020	1.78e-07	59.3	COG3947@1|root,COG3947@2|Bacteria,1V85E@1239|Firmicutes,4HWPH@91061|Bacilli,3IW0K@400634|Lysinibacillus	91061|Bacilli	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Response_reg,Trans_reg_C
FNPCBABE_01690	1235835.C814_00044	2.19e-83	262.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3WH9Z@541000|Ruminococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
FNPCBABE_01691	1122915.AUGY01000018_gene6246	0.0006	50.8	COG2374@1|root,COG3225@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3225@2|Bacteria,COG5492@2|Bacteria,1UI3P@1239|Firmicutes,4HJMZ@91061|Bacilli,27713@186822|Paenibacillaceae	91061|Bacilli	GN	S-layer homology domain	-	-	3.4.21.96	ko:K01361	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CBM_X2,Cadherin-like,Cohesin,LRR_5,Metallophos,NAGPA,PA,Peptidase_S8,Pur_ac_phosph_N,SLH,fn3_5
FNPCBABE_01692	1408311.JNJM01000010_gene1085	1.84e-15	83.2	2E1EY@1|root,32WTR@2|Bacteria,1VDET@1239|Firmicutes,24NZ7@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01698	931626.Awo_c16100	1.07e-38	149.0	COG3942@1|root,COG3942@2|Bacteria,1VFAV@1239|Firmicutes,25BXN@186801|Clostridia	186801|Clostridia	N	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHAP,CW_binding_1,GBS_Bsp-like,RicinB_lectin_2
FNPCBABE_01699	500632.CLONEX_04032	8.28e-121	386.0	COG0433@1|root,COG0433@2|Bacteria,1W186@1239|Firmicutes	1239|Firmicutes	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
FNPCBABE_01701	1519439.JPJG01000083_gene437	1.26e-08	65.9	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,2N77I@216572|Oscillospiraceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,Peptidase_M56
FNPCBABE_01703	545696.HOLDEFILI_01435	2.16e-130	390.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,3VQCE@526524|Erysipelotrichia	526524|Erysipelotrichia	S	RmuC domain protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
FNPCBABE_01704	428125.CLOLEP_02938	3.27e-125	367.0	COG0539@1|root,COG0539@2|Bacteria,1UV93@1239|Firmicutes,249P6@186801|Clostridia,3WH6M@541000|Ruminococcaceae	186801|Clostridia	J	S1 RNA binding domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
FNPCBABE_01705	1121334.KB911069_gene1717	6.52e-59	198.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,2504A@186801|Clostridia	186801|Clostridia	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
FNPCBABE_01706	1519439.JPJG01000019_gene338	9.14e-123	359.0	COG0560@1|root,COG0560@2|Bacteria,1TRRS@1239|Firmicutes,249NX@186801|Clostridia,2N6BI@216572|Oscillospiraceae	186801|Clostridia	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
FNPCBABE_01707	1410638.JHXJ01000012_gene2628	2.9e-113	337.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia,3WGAD@541000|Ruminococcaceae	186801|Clostridia	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
FNPCBABE_01708	411474.COPEUT_00441	1.38e-08	63.9	COG1721@1|root,COG1721@2|Bacteria,1UZHY@1239|Firmicutes,24DE8@186801|Clostridia	186801|Clostridia	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
FNPCBABE_01712	665950.HMPREF1025_01637	5.01e-190	552.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,27IE6@186928|unclassified Lachnospiraceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
FNPCBABE_01713	665950.HMPREF1025_01638	1.04e-90	275.0	COG0631@1|root,COG0631@2|Bacteria,1V2F5@1239|Firmicutes,24KFQ@186801|Clostridia,27KK6@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
FNPCBABE_01714	1410633.JHWR01000003_gene609	7.49e-48	183.0	COG0265@1|root,COG1196@1|root,COG1716@1|root,COG0265@2|Bacteria,COG1196@2|Bacteria,COG1716@2|Bacteria,1V0I9@1239|Firmicutes,24F2G@186801|Clostridia,27PEI@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,FIVAR,Trypsin_2
FNPCBABE_01717	411490.ANACAC_02875	1.69e-29	128.0	COG1813@1|root,COG1813@2|Bacteria,1V5YI@1239|Firmicutes,24R8T@186801|Clostridia	186801|Clostridia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
FNPCBABE_01718	1089550.ATTH01000001_gene2110	4.5e-34	120.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1FJEP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
FNPCBABE_01719	1203606.HMPREF1526_03009	1.16e-21	94.4	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,36GRI@31979|Clostridiaceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
FNPCBABE_01720	1196322.A370_01710	2.03e-24	109.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,36GAX@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77	ko:K00833,ko:K03851,ko:K12256,ko:K15372	ko00330,ko00410,ko00430,ko00780,ko01100,map00330,map00410,map00430,map00780,map01100	M00123,M00573,M00577	R00908,R01684,R03231,R05652,R08714	RC00006,RC00008,RC00062,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
FNPCBABE_01722	1232446.BAIE02000018_gene1461	5.96e-87	263.0	COG0745@1|root,COG0745@2|Bacteria,1TT73@1239|Firmicutes,2487E@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
FNPCBABE_01723	537013.CLOSTMETH_01407	2.65e-78	259.0	COG0642@1|root,COG2205@2|Bacteria,1TRD2@1239|Firmicutes,247M3@186801|Clostridia,3WJ0M@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
FNPCBABE_01725	1235835.C814_01868	2.59e-84	265.0	COG2348@1|root,COG2348@2|Bacteria,1TRZU@1239|Firmicutes,24AU8@186801|Clostridia,3WI7M@541000|Ruminococcaceae	186801|Clostridia	V	Methicillin resistance	femX	-	2.3.2.10,2.3.2.16	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	-	R08776,R08779	RC00055,RC00096	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
FNPCBABE_01726	398512.JQKC01000005_gene5374	1.78e-54	185.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,3WGKR@541000|Ruminococcaceae	186801|Clostridia	S	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
FNPCBABE_01727	33035.JPJF01000014_gene4839	7.57e-172	489.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,249UX@186801|Clostridia,3Y2CJ@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
FNPCBABE_01731	1235797.C816_02616	5.95e-49	161.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,2N7D7@216572|Oscillospiraceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
FNPCBABE_01733	1069534.LRC_16350	5.59e-70	214.0	COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4HH53@91061|Bacilli,3F7ID@33958|Lactobacillaceae	91061|Bacilli	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
FNPCBABE_01735	515620.EUBELI_20326	4.22e-70	225.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,25VW9@186806|Eubacteriaceae	186801|Clostridia	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
FNPCBABE_01736	189426.PODO_29870	6.4e-09	61.2	COG1309@1|root,COG1309@2|Bacteria,1V45P@1239|Firmicutes,4HHJU@91061|Bacilli,26VXN@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
FNPCBABE_01737	1410638.JHXJ01000001_gene1913	3.66e-84	257.0	COG0655@1|root,COG0655@2|Bacteria,1TRKM@1239|Firmicutes,24AD6@186801|Clostridia,3WJYP@541000|Ruminococcaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,Flavodoxin_2,SCP2
FNPCBABE_01738	515620.EUBELI_20279	5.15e-61	192.0	COG0764@1|root,COG0764@2|Bacteria,1VWSM@1239|Firmicutes,252FM@186801|Clostridia	186801|Clostridia	I	K02372 3R-hydroxymyristoyl ACP dehydrase	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
FNPCBABE_01739	1410638.JHXJ01000001_gene1912	2.14e-107	317.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WGIW@541000|Ruminococcaceae	186801|Clostridia	IQ	reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
FNPCBABE_01740	1410638.JHXJ01000001_gene1911	1.81e-264	755.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WGGB@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
FNPCBABE_01741	1410638.JHXJ01000001_gene1910	7.78e-21	84.7	COG0236@1|root,COG0236@2|Bacteria,1W4GV@1239|Firmicutes,255Z4@186801|Clostridia	186801|Clostridia	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
FNPCBABE_01744	1145276.T479_23625	1.73e-27	108.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,3IW7Y@400634|Lysinibacillus	91061|Bacilli	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
FNPCBABE_01746	1139219.I569_00373	1.17e-24	117.0	COG0714@1|root,COG4548@1|root,COG0714@2|Bacteria,COG4548@2|Bacteria,1TPW1@1239|Firmicutes,4HF8H@91061|Bacilli,4B127@81852|Enterococcaceae	91061|Bacilli	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5,CobT_C,VWA
FNPCBABE_01747	1196323.ALKF01000179_gene1597	2.43e-32	135.0	COG4548@1|root,COG4548@2|Bacteria,1TPW1@1239|Firmicutes,4HCPJ@91061|Bacilli,26WE9@186822|Paenibacillaceae	91061|Bacilli	P	Cobalamin biosynthesis protein CobT VWA domain	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
FNPCBABE_01749	1408324.JNJK01000014_gene2005	6.81e-117	339.0	COG1961@1|root,COG1961@2|Bacteria,1U31Z@1239|Firmicutes,249GR@186801|Clostridia,27MDN@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
FNPCBABE_01750	469378.Ccur_02760	1.22e-25	100.0	2C6KN@1|root,32Y69@2|Bacteria	2|Bacteria	S	VRR-NUC domain	-	-	-	-	-	-	-	-	-	-	-	-	VRR_NUC
FNPCBABE_01752	1203606.HMPREF1526_01814	8.69e-134	387.0	2DB92@1|root,2Z7UD@2|Bacteria,1URJ1@1239|Firmicutes,24FG5@186801|Clostridia,36RMU@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01753	641112.ACOK01000099_gene305	2.02e-57	202.0	COG3843@1|root,COG3843@2|Bacteria,1V2SB@1239|Firmicutes,24GQD@186801|Clostridia,3WGDT@541000|Ruminococcaceae	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
FNPCBABE_01754	203119.Cthe_3236	8.4e-23	91.3	2DSIE@1|root,33G9G@2|Bacteria,1VPGG@1239|Firmicutes,24TSQ@186801|Clostridia,3WSJG@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
FNPCBABE_01755	997296.PB1_04210	9.16e-18	76.3	COG3311@1|root,COG3311@2|Bacteria,1VFSN@1239|Firmicutes	1239|Firmicutes	K	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
FNPCBABE_01756	1117315.AHCA01000008_gene4082	9.9e-116	382.0	COG0210@1|root,COG0551@1|root,COG0210@2|Bacteria,COG0551@2|Bacteria,1MVWI@1224|Proteobacteria,1RN1N@1236|Gammaproteobacteria,2Q0UU@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	COG0210 Superfamily I DNA and RNA helicases	helD	-	3.6.4.12	ko:K03658	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_IV_N,UvrD-helicase,UvrD_C,zf-C4_Topoisom
FNPCBABE_01757	1378168.N510_03158	1.55e-222	629.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes	1239|Firmicutes	L	resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
FNPCBABE_01758	1160721.RBI_II00419	3.71e-115	356.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3WG90@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
FNPCBABE_01762	1120746.CCNL01000011_gene1736	9.64e-107	319.0	COG1281@1|root,COG1281@2|Bacteria,2NPFF@2323|unclassified Bacteria	2|Bacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
FNPCBABE_01763	1514668.JOOA01000002_gene3489	1.51e-71	226.0	COG2227@1|root,COG2227@2|Bacteria,1V218@1239|Firmicutes,25EUC@186801|Clostridia,3WSKE@541000|Ruminococcaceae	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
FNPCBABE_01764	428125.CLOLEP_02383	1.07e-29	108.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,3WKB9@541000|Ruminococcaceae	186801|Clostridia	S	protein, YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
FNPCBABE_01765	1121334.KB911066_gene504	7.07e-141	403.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,3WGQ0@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
FNPCBABE_01766	580331.Thit_0786	8.28e-14	74.3	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,42FJC@68295|Thermoanaerobacterales	186801|Clostridia	K	aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2,GntR
FNPCBABE_01767	411463.EUBVEN_02376	2.11e-94	288.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia,25VUY@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase component	ytrB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
FNPCBABE_01768	1120746.CCNL01000017_gene2947	6.09e-23	112.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
FNPCBABE_01769	1282887.AUJG01000001_gene1541	2.44e-94	278.0	COG3760@1|root,COG3760@2|Bacteria,1V1JF@1239|Firmicutes,24FVD@186801|Clostridia	186801|Clostridia	J	YbaK proline--tRNA ligase associated domain protein	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
FNPCBABE_01771	97139.C824_03107	2.33e-05	48.1	COG1476@1|root,COG1476@2|Bacteria,1VHT2@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
FNPCBABE_01772	428125.CLOLEP_03740	1.05e-126	376.0	COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,3WI13@541000|Ruminococcaceae	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
FNPCBABE_01773	428125.CLOLEP_03741	1.11e-152	441.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,3WG94@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
FNPCBABE_01774	1120746.CCNL01000017_gene3029	5.12e-147	431.0	COG0128@1|root,COG0128@2|Bacteria,2NNZ5@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
FNPCBABE_01775	537013.CLOSTMETH_02791	9.96e-123	364.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,3WGPK@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
FNPCBABE_01776	428125.CLOLEP_03745	2.27e-120	352.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,3WI06@541000|Ruminococcaceae	186801|Clostridia	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
FNPCBABE_01777	428125.CLOLEP_03746	1.34e-185	522.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,3WG9J@541000|Ruminococcaceae	186801|Clostridia	E	synthase	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS14395	DAHP_synth_1
FNPCBABE_01778	428125.CLOLEP_03749	4e-57	184.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,3WJBW@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
FNPCBABE_01779	428125.CLOLEP_03750	1.2e-98	297.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WGF4@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,Shikimate_DH,Shikimate_dh_N
FNPCBABE_01780	428125.CLOLEP_03305	2.54e-253	754.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,3WG8U@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent helicase deoxyribonuclease subunit B	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
FNPCBABE_01781	1121334.KB911069_gene1504	2.21e-281	831.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,3WGE1@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
FNPCBABE_01782	1410630.JNKP01000001_gene1813	2.05e-05	51.6	COG3247@1|root,COG3247@2|Bacteria,1VFKP@1239|Firmicutes,24RBX@186801|Clostridia,27NK8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
FNPCBABE_01783	1410670.JHXF01000010_gene522	7.55e-146	424.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WG83@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
FNPCBABE_01784	411473.RUMCAL_02985	5.03e-33	116.0	2EGCF@1|root,33A48@2|Bacteria,1TV0R@1239|Firmicutes,2586M@186801|Clostridia,3WM1Y@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01785	658655.HMPREF0988_00619	8.17e-120	349.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,27IU0@186928|unclassified Lachnospiraceae	186801|Clostridia	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
FNPCBABE_01786	1449335.JQLG01000004_gene618	1.57e-85	306.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli,27FS7@186828|Carnobacteriaceae	91061|Bacilli	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
FNPCBABE_01787	1408322.JHYK01000002_gene1254	5.48e-97	301.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,27JDN@186928|unclassified Lachnospiraceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
FNPCBABE_01788	411483.FAEPRAA2165_02425	5.85e-37	127.0	2CCD5@1|root,32RVD@2|Bacteria,1UPQI@1239|Firmicutes,25HM0@186801|Clostridia,3WREV@541000|Ruminococcaceae	186801|Clostridia	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
FNPCBABE_01789	1235792.C808_04249	1.88e-99	296.0	COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,27JI9@186928|unclassified Lachnospiraceae	186801|Clostridia	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
FNPCBABE_01790	909943.HIMB100_00013920	0.000396	47.8	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2TUI7@28211|Alphaproteobacteria,4BQK8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	CDP-alcohol phosphatidyltransferase	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
FNPCBABE_01791	428125.CLOLEP_02998	0.0	959.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,2486F@186801|Clostridia,3WGI2@541000|Ruminococcaceae	186801|Clostridia	O	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03697	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small
FNPCBABE_01792	411463.EUBVEN_02432	3.11e-120	353.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,25UYF@186806|Eubacteriaceae	186801|Clostridia	P	sugar transport system permease	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
FNPCBABE_01793	1504822.CCNO01000011_gene91	5.23e-123	359.0	COG1175@1|root,COG1175@2|Bacteria,2NQWJ@2323|unclassified Bacteria	2|Bacteria	G	Binding-protein-dependent transport system inner membrane component	msmF	-	-	ko:K10118,ko:K15771	ko02010,map02010	M00196,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2,3.A.1.1.28	-	-	BPD_transp_1
FNPCBABE_01794	665956.HMPREF1032_01809	9.81e-201	570.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	amyE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8,TAT_signal
FNPCBABE_01795	1105031.HMPREF1141_3054	6.09e-11	70.1	COG5578@1|root,COG5578@2|Bacteria,1V87X@1239|Firmicutes,24PJA@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
FNPCBABE_01800	1235835.C814_00341	3.15e-34	137.0	COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,249SB@186801|Clostridia,3WKYR@541000|Ruminococcaceae	186801|Clostridia	L	YqaJ viral recombinase family	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
FNPCBABE_01801	1391646.AVSU01000017_gene3118	3.17e-129	409.0	COG0272@1|root,COG0507@1|root,COG0272@2|Bacteria,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,25QNC@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
FNPCBABE_01804	1408437.JNJN01000035_gene1812	3.78e-66	208.0	COG3481@1|root,COG3481@2|Bacteria,1TQEK@1239|Firmicutes,24BRR@186801|Clostridia	186801|Clostridia	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
FNPCBABE_01806	556261.HMPREF0240_04024	5.12e-92	286.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia,36F59@31979|Clostridiaceae	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
FNPCBABE_01807	1235802.C823_02334	3.2e-233	657.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,25VII@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
FNPCBABE_01808	1232447.BAHW02000028_gene2239	2.28e-196	549.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,2689A@186813|unclassified Clostridiales	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
FNPCBABE_01809	537007.BLAHAN_04166	1.14e-190	542.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3XZFW@572511|Blautia	186801|Clostridia	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
FNPCBABE_01810	411462.DORLON_02853	2.29e-232	652.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
FNPCBABE_01811	457396.CSBG_01643	4.24e-66	218.0	COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,248K0@186801|Clostridia,36FT7@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
FNPCBABE_01812	411474.COPEUT_01919	1.06e-70	215.0	2DU3D@1|root,32UWH@2|Bacteria,1V6ZJ@1239|Firmicutes,24PSR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4829
FNPCBABE_01814	428125.CLOLEP_02095	2.72e-57	180.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,3WJE1@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
FNPCBABE_01815	428125.CLOLEP_02912	8.72e-55	182.0	COG1396@1|root,COG1396@2|Bacteria,1V2ZX@1239|Firmicutes,24EC9@186801|Clostridia,3WIEA@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
FNPCBABE_01816	428125.CLOLEP_02913	2.06e-82	251.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3WJCY@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
FNPCBABE_01817	428125.CLOLEP_02914	7.35e-199	557.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,3WG9H@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
FNPCBABE_01818	478749.BRYFOR_06424	3.16e-20	94.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia	186801|Clostridia	GM	capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
FNPCBABE_01819	1120746.CCNL01000013_gene2030	1.79e-87	258.0	COG0822@1|root,COG0822@2|Bacteria,2NPRS@2323|unclassified Bacteria	2|Bacteria	C	NifU-like N terminal domain	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
FNPCBABE_01820	1120746.CCNL01000013_gene2029	3.42e-206	579.0	COG1104@1|root,COG1104@2|Bacteria,2NNVR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
FNPCBABE_01821	663278.Ethha_2290	2.36e-68	210.0	COG0328@1|root,COG0328@2|Bacteria,1V4A0@1239|Firmicutes,24FSS@186801|Clostridia,3WISH@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
FNPCBABE_01823	537013.CLOSTMETH_00769	5.65e-68	216.0	COG3764@1|root,COG3764@2|Bacteria,1V9CM@1239|Firmicutes,24UPX@186801|Clostridia,3WMIS@541000|Ruminococcaceae	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
FNPCBABE_01825	428125.CLOLEP_02541	1.66e-98	295.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3WGAW@541000|Ruminococcaceae	186801|Clostridia	L	Hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
FNPCBABE_01826	1160721.RBI_I01468	0.0	1047.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3WGEI@541000|Ruminococcaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
FNPCBABE_01827	483218.BACPEC_00627	1.06e-222	625.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,268FU@186813|unclassified Clostridiales	186801|Clostridia	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
FNPCBABE_01829	428125.CLOLEP_03321	0.0	934.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,3WGBK@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
FNPCBABE_01830	1120746.CCNL01000013_gene1968	8.62e-278	766.0	COG1156@1|root,COG1156@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
FNPCBABE_01831	1121334.KB911069_gene1487	1.48e-87	264.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,3WH3C@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
FNPCBABE_01833	661087.HMPREF1008_00694	1.03e-64	197.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	yphJ	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD,Cupin_2
FNPCBABE_01834	1160721.RBI_II00300	1.08e-308	854.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3WH8S@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs1	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
FNPCBABE_01838	428125.CLOLEP_01895	1.05e-83	252.0	COG0503@1|root,COG0503@2|Bacteria,1V1XS@1239|Firmicutes,25QBJ@186801|Clostridia,3WIP6@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
FNPCBABE_01839	1196322.A370_05779	4.07e-47	154.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,36JIP@31979|Clostridiaceae	186801|Clostridia	FG	Hit family	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
FNPCBABE_01840	428125.CLOLEP_00450	2.61e-62	202.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3WJFE@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
FNPCBABE_01841	428125.CLOLEP_00451	8.13e-231	645.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,3WGNU@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
FNPCBABE_01842	428125.CLOLEP_00452	2.61e-170	491.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,3WGI9@541000|Ruminococcaceae	186801|Clostridia	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
FNPCBABE_01843	883081.HMPREF9698_00103	2.8e-12	62.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,4HNIZ@91061|Bacilli,27GR9@186828|Carnobacteriaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
FNPCBABE_01844	411470.RUMGNA_02867	3.29e-18	84.3	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,3Y029@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
FNPCBABE_01845	1029718.SFBM_1150	1.66e-114	333.0	COG1244@1|root,COG1244@2|Bacteria,1UZ5M@1239|Firmicutes,24AIM@186801|Clostridia,36G6G@31979|Clostridiaceae	186801|Clostridia	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01846	1203606.HMPREF1526_02400	1.61e-101	301.0	COG1738@1|root,COG1738@2|Bacteria,1TSAY@1239|Firmicutes,24EFG@186801|Clostridia,36Q0T@31979|Clostridiaceae	186801|Clostridia	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
FNPCBABE_01849	272558.10172614	1.71e-05	55.1	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,1ZAVV@1386|Bacillus	91061|Bacilli	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
FNPCBABE_01850	557436.Lreu_0830	6.49e-17	84.3	292Y9@1|root,2ZQFR@2|Bacteria,1W1P1@1239|Firmicutes,4I14X@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01851	999413.HMPREF1094_00594	2.74e-44	160.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,3VNX4@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
FNPCBABE_01852	483216.BACEGG_01108	6.48e-10	60.5	2C15K@1|root,34BD6@2|Bacteria,4P6AU@976|Bacteroidetes,2FTXZ@200643|Bacteroidia,4ARYP@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01856	865861.AZSU01000010_gene729	9.11e-57	187.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,36EIP@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
FNPCBABE_01857	1410630.JNKP01000001_gene1953	1.25e-73	225.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,27M94@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
FNPCBABE_01858	428125.CLOLEP_00565	7.66e-150	435.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,3WHE1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
FNPCBABE_01859	428125.CLOLEP_00566	1.35e-255	708.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WHJX@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
FNPCBABE_01860	445972.ANACOL_03704	6.89e-38	132.0	COG0433@1|root,COG0433@2|Bacteria,1VF8X@1239|Firmicutes,24N9T@186801|Clostridia,3WJSW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01862	428125.CLOLEP_01486	8.82e-56	183.0	COG0283@1|root,COG0283@2|Bacteria,1VB1M@1239|Firmicutes,24YPD@186801|Clostridia,3WSQB@541000|Ruminococcaceae	186801|Clostridia	F	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
FNPCBABE_01864	180332.JTGN01000022_gene1505	9.61e-05	52.8	COG3408@1|root,COG5492@1|root,COG3408@2|Bacteria,COG5492@2|Bacteria,1TUGS@1239|Firmicutes,24AS7@186801|Clostridia	186801|Clostridia	G	F5 8 type C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,F5_F8_type_C,FIVAR
FNPCBABE_01870	1280671.AUJH01000010_gene3518	1.43e-237	673.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,4BXQH@830|Butyrivibrio	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
FNPCBABE_01871	1042156.CXIVA_17750	4.13e-35	121.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,36KJQ@31979|Clostridiaceae	186801|Clostridia	G	HPr family	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
FNPCBABE_01872	471855.Shel_13280	4.81e-261	738.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,2GJU4@201174|Actinobacteria,4CUBT@84998|Coriobacteriia	84998|Coriobacteriia	G	TIGRFAM PTS system, fructose subfamily, IIC	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
FNPCBABE_01873	1410661.JNKW01000008_gene2116	1.02e-118	350.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
FNPCBABE_01874	411467.BACCAP_02217	1.17e-88	270.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia,269MK@186813|unclassified Clostridiales	186801|Clostridia	K	DeoR C terminal sensor domain	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
FNPCBABE_01875	1280694.AUJQ01000003_gene1501	3.72e-24	97.8	COG5652@1|root,COG5652@2|Bacteria,1UQX6@1239|Firmicutes,258Q5@186801|Clostridia,3NHFC@46205|Pseudobutyrivibrio	186801|Clostridia	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
FNPCBABE_01876	428125.CLOLEP_02353	2.48e-149	440.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3WHF6@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
FNPCBABE_01878	489825.LYNGBM3L_56700	0.000436	47.8	COG1994@1|root,COG1994@2|Bacteria,1G05Y@1117|Cyanobacteria,1H8MI@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the peptidase M50B family	-	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
FNPCBABE_01879	1120746.CCNL01000011_gene1718	0.0	911.0	COG1032@1|root,COG1032@2|Bacteria,2NNKI@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
FNPCBABE_01880	1120746.CCNL01000011_gene1719	2.58e-67	213.0	COG5011@1|root,COG5011@2|Bacteria	2|Bacteria	C	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
FNPCBABE_01881	871963.Desdi_0549	1.41e-24	105.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,261QS@186807|Peptococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
FNPCBABE_01882	1120746.CCNL01000011_gene1739	1.01e-227	639.0	COG1066@1|root,COG1066@2|Bacteria,2NNQG@2323|unclassified Bacteria	2|Bacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
FNPCBABE_01883	1105031.HMPREF1141_3059	5.43e-36	133.0	28NR9@1|root,2ZBQJ@2|Bacteria,1UZEN@1239|Firmicutes,24G0V@186801|Clostridia,36I0Y@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01884	1120746.CCNL01000011_gene1743	1.59e-137	400.0	COG4974@1|root,COG4974@2|Bacteria,2NP4H@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
FNPCBABE_01885	742765.HMPREF9457_01771	1.16e-255	708.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,27V70@189330|Dorea	186801|Clostridia	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
FNPCBABE_01886	873448.STRPO_0013	0.00091	45.4	COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1V758@1239|Firmicutes,4HIKZ@91061|Bacilli	91061|Bacilli	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
FNPCBABE_01887	1120945.ATUW01000004_gene432	2.88e-38	130.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4D5ZB@85005|Actinomycetales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
FNPCBABE_01888	1121334.KB911075_gene1802	0.0	1134.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
FNPCBABE_01889	411483.FAEPRAA2165_00683	2.1e-19	80.9	2CBNP@1|root,33J1I@2|Bacteria,1VP33@1239|Firmicutes,24WEX@186801|Clostridia,3WQQK@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01890	537013.CLOSTMETH_00282	5.45e-28	103.0	COG2026@1|root,COG2026@2|Bacteria,1UHB7@1239|Firmicutes,24T4T@186801|Clostridia,3WMC8@541000|Ruminococcaceae	186801|Clostridia	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
FNPCBABE_01891	397290.C810_02057	6.16e-195	550.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,27I60@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5,Lactamase_B
FNPCBABE_01892	537013.CLOSTMETH_03303	1.64e-194	577.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WG9Y@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
FNPCBABE_01893	1121344.JHZO01000001_gene443	1.02e-33	120.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3WK18@541000|Ruminococcaceae	186801|Clostridia	K	regulatory protein, arsR	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
FNPCBABE_01894	1410632.JHWW01000002_gene1988	2.82e-61	199.0	2BMR8@1|root,32GAN@2|Bacteria,1UR6G@1239|Firmicutes,25909@186801|Clostridia,27MMC@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01895	1216932.CM240_0035	3.19e-19	96.3	COG4990@1|root,COG4990@2|Bacteria,1V714@1239|Firmicutes,24JG8@186801|Clostridia,36JN8@31979|Clostridiaceae	186801|Clostridia	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
FNPCBABE_01896	397291.C804_06447	5.54e-49	169.0	COG5527@1|root,COG5527@2|Bacteria,1V1XJ@1239|Firmicutes,24PSJ@186801|Clostridia,27SKW@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Initiator Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
FNPCBABE_01897	1321782.HMPREF1986_00138	9.12e-59	184.0	COG4679@1|root,COG4679@2|Bacteria,1VBJ4@1239|Firmicutes,24RVP@186801|Clostridia,2PTXG@265975|Oribacterium	186801|Clostridia	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
FNPCBABE_01898	936573.HMPREF1147_1611	4.74e-38	129.0	COG3620@1|root,COG3620@2|Bacteria,1V77U@1239|Firmicutes,4H4Q3@909932|Negativicutes	909932|Negativicutes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
FNPCBABE_01899	585501.HMPREF6123_0869	8.73e-88	266.0	2E4MT@1|root,32ZGR@2|Bacteria,1W3T2@1239|Firmicutes,256Y8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01900	428125.CLOLEP_03218	1.39e-67	206.0	2C5R4@1|root,31VPY@2|Bacteria,1V8EP@1239|Firmicutes,24JPJ@186801|Clostridia,3WJKA@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
FNPCBABE_01901	428125.CLOLEP_03219	4.6e-240	664.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,3WHRE@541000|Ruminococcaceae	186801|Clostridia	M	plasmid recombination	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
FNPCBABE_01902	428125.CLOLEP_03220	5.55e-215	601.0	COG3598@1|root,COG3598@2|Bacteria,1TU5N@1239|Firmicutes,247KK@186801|Clostridia,3WSPN@541000|Ruminococcaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,PriCT_1,Prim-Pol
FNPCBABE_01903	1519439.JPJG01000056_gene2250	3.05e-49	159.0	2AQJ5@1|root,31FRY@2|Bacteria,1V6TG@1239|Firmicutes,24JD1@186801|Clostridia,2N8GP@216572|Oscillospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01904	428125.CLOLEP_03222	2.76e-247	680.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WHJS@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
FNPCBABE_01905	428125.CLOLEP_03223	3.84e-32	112.0	2E5UB@1|root,331IU@2|Bacteria,1VH5Y@1239|Firmicutes,24S88@186801|Clostridia,3WKFA@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mga
FNPCBABE_01906	877411.JMMA01000002_gene2598	4.02e-157	442.0	COG1211@1|root,COG1211@2|Bacteria,1TS1B@1239|Firmicutes,2484P@186801|Clostridia,3WJ9I@541000|Ruminococcaceae	186801|Clostridia	I	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
FNPCBABE_01907	877411.JMMA01000002_gene2599	9.18e-157	451.0	COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,247JP@186801|Clostridia,3WJ79@541000|Ruminococcaceae	186801|Clostridia	GM	epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
FNPCBABE_01908	1286171.EAL2_c20090	4.61e-39	152.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,25X1J@186806|Eubacteriaceae	186801|Clostridia	M	LicD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
FNPCBABE_01909	471855.Shel_21300	6.04e-71	221.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria,4CW2F@84998|Coriobacteriia	84998|Coriobacteriia	M	Acetyltransferase (GNAT) family	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
FNPCBABE_01910	742738.HMPREF9460_02046	3.9e-120	347.0	2E1QU@1|root,32X10@2|Bacteria,1VAGG@1239|Firmicutes,24H1T@186801|Clostridia	186801|Clostridia	S	RloB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	RloB
FNPCBABE_01911	742738.HMPREF9460_02047	9.89e-261	720.0	COG1106@1|root,COG1106@2|Bacteria,1TSBY@1239|Firmicutes,249DS@186801|Clostridia,26923@186813|unclassified Clostridiales	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
FNPCBABE_01912	1105031.HMPREF1141_2114	9.69e-27	106.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,36EWT@31979|Clostridiaceae	186801|Clostridia	O	SPFH domain Band 7 family	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
FNPCBABE_01913	1120971.AUCA01000007_gene2156	3.81e-09	59.3	COG1585@1|root,COG1585@2|Bacteria,1VCUJ@1239|Firmicutes,4HPB4@91061|Bacilli	91061|Bacilli	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
FNPCBABE_01916	1235799.C818_01939	9.23e-92	274.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,27K3J@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
FNPCBABE_01919	1385512.N784_13830	1.45e-16	83.6	28KBJ@1|root,2Z9YJ@2|Bacteria,1V10F@1239|Firmicutes,4HDQW@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01921	877414.ATWA01000002_gene1127	2.95e-53	182.0	COG0111@1|root,COG0111@2|Bacteria,1TPUC@1239|Firmicutes,253BG@186801|Clostridia,26810@186813|unclassified Clostridiales	186801|Clostridia	EH	Dipicolinate synthase subunit A N-terminal domain	spoVFA	-	-	ko:K06410	-	-	-	-	ko00000	-	-	-	2-Hacid_dh_C,AlaDh_PNT_C,DpaA_N
FNPCBABE_01922	1105031.HMPREF1141_0806	2.94e-79	241.0	COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,24HE6@186801|Clostridia,36I49@31979|Clostridiaceae	186801|Clostridia	H	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)	spoVFB	-	-	ko:K06411	-	-	-	-	ko00000	-	-	-	Flavoprotein
FNPCBABE_01923	768710.DesyoDRAFT_1911	3.45e-24	92.8	COG1476@1|root,COG1476@2|Bacteria,1VEIS@1239|Firmicutes,24R6J@186801|Clostridia,265K6@186807|Peptococcaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
FNPCBABE_01924	665956.HMPREF1032_00166	3.9e-28	102.0	COG1396@1|root,COG1396@2|Bacteria,1UHV9@1239|Firmicutes,25E41@186801|Clostridia,3WRBW@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
FNPCBABE_01927	428125.CLOLEP_02625	9.63e-205	595.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3WGHX@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
FNPCBABE_01929	718252.FP2_09220	1.69e-18	80.1	2CF79@1|root,32RHV@2|Bacteria,1V7CD@1239|Firmicutes,24QYF@186801|Clostridia,3WMFW@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
FNPCBABE_01930	428125.CLOLEP_02423	3.42e-38	129.0	2E6AD@1|root,330Y9@2|Bacteria,1VGZN@1239|Firmicutes,2589N@186801|Clostridia,3WM9E@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01931	411489.CLOL250_02700	5.62e-86	255.0	COG0454@1|root,COG0456@2|Bacteria,1V3IC@1239|Firmicutes,24HK5@186801|Clostridia,36JMS@31979|Clostridiaceae	186801|Clostridia	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,Acetyltransf_7
FNPCBABE_01932	717605.Theco_1066	2.91e-74	253.0	COG1595@1|root,COG1595@2|Bacteria,1VTM3@1239|Firmicutes,4HWYI@91061|Bacilli,26WAY@186822|Paenibacillaceae	91061|Bacilli	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
FNPCBABE_01934	1160721.RBI_I01604	9.58e-51	169.0	COG2856@1|root,COG2856@2|Bacteria,1V9YR@1239|Firmicutes,258D5@186801|Clostridia,3WMGC@541000|Ruminococcaceae	186801|Clostridia	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
FNPCBABE_01936	428125.CLOLEP_01329	5.08e-50	179.0	COG4974@1|root,COG4974@2|Bacteria,1VU9F@1239|Firmicutes,25FU1@186801|Clostridia,3WIT0@541000|Ruminococcaceae	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Arm-DNA-bind_2,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
FNPCBABE_01937	883109.HMPREF0380_00748	1.21e-37	133.0	2C15H@1|root,332DU@2|Bacteria,1VIK1@1239|Firmicutes,24RAR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
FNPCBABE_01938	1408436.JHXY01000049_gene257	5.86e-124	355.0	COG2184@1|root,COG2184@2|Bacteria,1TPUZ@1239|Firmicutes,248XF@186801|Clostridia,25W8Z@186806|Eubacteriaceae	186801|Clostridia	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Bro-N,Fic
FNPCBABE_01939	1235799.C818_03964	3.65e-181	513.0	COG1846@1|root,COG2184@1|root,COG1846@2|Bacteria,COG2184@2|Bacteria,1TNY6@1239|Firmicutes,249XE@186801|Clostridia,27KEX@186928|unclassified Lachnospiraceae	186801|Clostridia	D	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
FNPCBABE_01940	665950.HMPREF1025_02619	1.4e-84	253.0	COG1502@1|root,COG1502@2|Bacteria,1V2WP@1239|Firmicutes,24DM2@186801|Clostridia,27RU2@186928|unclassified Lachnospiraceae	186801|Clostridia	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
FNPCBABE_01941	471855.Shel_19070	2.17e-94	297.0	COG0732@1|root,COG0732@2|Bacteria,2HV7Z@201174|Actinobacteria,4CXW9@84998|Coriobacteriia	84998|Coriobacteriia	V	type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
FNPCBABE_01942	1392491.JIAE01000001_gene727	0.0	942.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,3WGXV@541000|Ruminococcaceae	186801|Clostridia	L	N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
FNPCBABE_01943	180332.JTGN01000020_gene1238	1.35e-32	114.0	COG3655@1|root,COG3655@2|Bacteria,1VEM0@1239|Firmicutes,24QPN@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
FNPCBABE_01945	742735.HMPREF9467_03109	2.41e-23	90.9	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,24MDN@186801|Clostridia,221HQ@1506553|Lachnoclostridium	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
FNPCBABE_01946	1235802.C823_06031	4.31e-20	83.2	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,24RTS@186801|Clostridia	186801|Clostridia	S	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
FNPCBABE_01947	742735.HMPREF9467_03110	6e-28	102.0	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,24MDN@186801|Clostridia,221HQ@1506553|Lachnoclostridium	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
FNPCBABE_01948	469596.HMPREF9488_02263	3.26e-09	55.8	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,3VU5D@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
FNPCBABE_01949	742735.HMPREF9467_03106	1.91e-256	708.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,21YWZ@1506553|Lachnoclostridium	186801|Clostridia	L	DNA binding domain of tn916 integrase	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_integrase
## 1587 queries scanned
## Total time (seconds): 610.6792793273926
## Rate: 2.60 q/s