LOCUS       gnlProkkaIHKOLFOI_30   31898 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IHKOLFOI_30.
ACCESSION   gnlProkkaIHKOLFOI_30
VERSION     gnlProkkaIHKOLFOI_30
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 12:25:50
            Original ID  :: gnl|Prokka|IHKOLFOI_30
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 31898
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..31898
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1951:26898]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1952..26898
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..31898
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..31898
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..584
                     /locus_tag="ctg30_1"
                     /transl_table=11
                     /translation="MNNSQKYLTKYQYVSTLDVACGIGRWADALPEDIKEYCGMDFSEE
                     LVAIANKRNHRNRFFYCVGGANEIAAVLKKNGKGLYNRILIVGILIYLNDVDMADSLRQ
                     IEKVCETKSVICIREPIAIEERLTLKDFFSEELNDYYNAIYRTRDELMVSINEMFLNKG
                     FRIKEEGFLFDDDALNNRKETAQYYYILER"
     CDS             591..914
                     /locus_tag="ctg30_2"
                     /transl_table=11
                     /translation="MYREKVGIIGGFGAYATLNFYKRLLEEFASESERNYPHIIMDNNF
                     TMPSRTRALLYGEAYDEVVDGISDSIQLMMQNDVSKIILVCGTAHYFLNDVYKKFRRQK
                     KKL"
     CDS             929..1318
                     /locus_tag="ctg30_3"
                     /transl_table=11
                     /translation="MVEELKLKDEGEVLVIAAEGALQKKLYQTRLKKYGIKCVNPDEED
                     FIDIRYFIECVKRNELNEDLVHQFGNFLDKFGKRNVVLGCTEFPVLVEYIDKCQKTEST
                     VNLRKQYCFYDPLQMTIKWLKENLQ"
     CDS             1336..1938
                     /locus_tag="ctg30_4"
                     /transl_table=11
                     /translation="MSRYIFLFDLDSTVTKQEILPTISKRLGIYERMSELTESTMRGEI
                     PFKQSFLQRVELLKDVPVSEVNEMVSRIQLNNHLVDFIQKNHDRCHIVTGNLDVWIDGV
                     IRKLGMERNTFCSKAIVKNDYIEDVFNIVDKNAVIGQMVLPFVAIGDGNNDAEMIEAAE
                     VGIGYGGVREIAPAVLACASHAIYDEEKLVEFLERLL"
     CDS             1952..2602
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_5"
                     /sec_met_domain="NTP_transf_3 (E-value: 3e-14, bitscore:
                     45.2, seeds: 297, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.3e-07,
                     bitscore: 22.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVSRTVIISCAGMGNRLGLGTTKALVEVEGKPLIMHHLEKLKDE
                     SDIRVVVGYQAEKVINVVRKYRKDVVFVFNHNYRETGTGASVALASQYANEYILSLDGD
                     LIIHPDDMKKILECDHEFVSGGIPDTDEPWMLQTYKDDGKEFVSAFSKNIGNYEWNGIT
                     QMKSAKIKNGQGHVFQLIEPYLPIPFLELRTREIDTVNDYERAVEWVRNNFRE"
     CDS             2636..2788
                     /locus_tag="ctg30_6"
                     /transl_table=11
                     /translation="MKRNILLNPGPATTTDTVKQAQIVPDICPREQEFVEIMKQIRTDL
                     VKIVH"
     CDS             2840..3766
                     /NRPS_PKS="Domain: Aminotran_5 (5-234). E-value: 5.3e-33.
                     Score: 106.3. Matches aSDomain:
                     nrpspksdomains_ctg30_7_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 67.6; E-value:
                     1.6e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_7"
                     /sec_met_domain="Aminotran_5 (E-value: 6e-31, bitscore:
                     99.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVCLNSLLPEEKKILVVNNGAYSSRAVEICKYYGLPFIDLKFPI
                     DERPSLEVIERTLKENEDIALVYTTHNETGTGILNPVREIGALVHQYHAVFVVDTTSTY
                     AMRPINIKEDNIDFCMASAQKGLMAMTGVSFVVGKRSIIEQSKDYPKRSYYCNLYLQYD
                     YFEKHREMHFTPPVQTIYAMRQALKEYFAEGEQEKWKRHTRVFVALHQGLEELGFQDVI
                     KREWQAGLVITVKYPDDPNWSFSAIHDYCYERGFTIYPGKINNTETFRLCALGAVDEAD
                     IQEFFKVFQAGLESMKVAVPVFYREEK"
     aSDomain        2855..3541
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg30_7_Aminotran_5.1"
                     /evalue="5.30E-33"
                     /label="ctg30_7_Aminotran_5.1"
                     /locus_tag="ctg30_7"
                     /protein_end="234"
                     /protein_start="5"
                     /score="106.3"
                     /tool="antismash"
                     /translation="NSLLPEEKKILVVNNGAYSSRAVEICKYYGLPFIDLKFPIDERPS
                     LEVIERTLKENEDIALVYTTHNETGTGILNPVREIGALVHQYHAVFVVDTTSTYAMRPI
                     NIKEDNIDFCMASAQKGLMAMTGVSFVVGKRSIIEQSKDYPKRSYYCNLYLQYDYFEKH
                     REMHFTPPVQTIYAMRQALKEYFAEGEQEKWKRHTRVFVALHQGLEELGFQDVIKREWQ
                     AGLVITV"
     CDS             3796..4506
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_8"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.9e-13, bitscore:
                     42.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNEIAILMAAGLGTRMRPLTDKIAKPLVSVHGKSLIETIIEAL
                     QQRGVTIIYVVVGYRKEQFAYLTEKYDHLVLIENKEYLKKNNISSLYAVGDILGSKDCF
                     ICEADLYVTDPAIFLRKFKKSCYFGKMIPGYSDDWVFEIREGKITRVGKGGTDTYNMAG
                     ISYWKKEDAVLIRNAIQEAYKTAGHEQLFWDEIVDQELDNLDVTVEEIPADSVVEIDTF
                     DELCKIDETYRNAE"
     CDS             4521..5654
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 46.3;
                     E-value: 4.3e-14)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_9"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.6e-19, bitscore:
                     60.9, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-15, bitscore:
                     48.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVTDFIKQIKKVGIKTLTGVPDSALRPFCDYINGVGKEEFTHYV
                     PANEGAAVGIAIGEYLSTGVPACVYMQNSGLGNIVNPITSLANEEVYGIPMLLLVGYRG
                     EPGKKDEPQHKYMGKITESLLDVLGIEHMVLGKELTEQEISEGFGRAAQKLKEGQQFAF
                     VLKKDFLEIEEKSIYVNDNSLIREDVIAQIIESLDESDVVVSTTGKISREVYEQSDRIN
                     GSHAQDFLTVGGMGHASMIAFGIAENAKEKRVYCMDGDGAELMHMGSLAFIAKQKPQNF
                     VHICLNNEAHESVGGMPTGCVGLSYAEVARTVGYEAVYYIDTMEELKQVLHDIKPERKL
                     TFIEIKVSMQSRADLGRPKETAAENKENFMKYHGVKE"
     CDS             5651..6946
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 210.2;
                     E-value: 6e-64)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_10"
                     /sec_met_domain="CTP_transf_like (E-value: 4.5e-16,
                     bitscore: 50.8, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 3.8e-118, bitscore:
                     385.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.8e-67, bitscore:
                     218.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVYACFCTDVIHEGHLNIIHEAKKYGKVIAGVLSDAAMIRYNR
                     FPTVSFEERKKMLEQIPEVDEVVVQNEVMYGNILEQIKPDYVIHGDNWLNDPMEVIRDN
                     VIENLAKWGGQLIEVPYTYNEQVKNIEAVMRERAAMPEYRRKRLRQLLKLCPIVKTLEV
                     HSGLTGLIAEKTVVANQGEIDQFDAMWLSSLCDSTAKGKPDIELVDMSSRLRTVDDVLE
                     VTTKPIILDGDTGGMIEHFVYNVRTLERIGVSAVIIEDKTGLKKNSLFGTEVEQTQDSI
                     ENFTAKIRAGKHAQRTQDFMIIARIESLILEKGMDDALERASAYVEAGADGIMIHSRKK
                     EPDEIFEFCDKFRNRDAVTPIVVVPTSYNATYESELQAHGVNIVIYANQLTRSAFAAMQ
                     KTATDILTYHRAKEIDDRLMPIKEIITLIDEI"
     CDS             6959..8902
                     /locus_tag="ctg30_11"
                     /transl_table=11
                     /translation="MLVDRLTLQKIDDIGRNIMNDMSIKEQMMQLTKQCILSNDDKAML
                     ECLQIYKSSFGYDDFYITSLSSLRITPEPLVSLIYIKQPDEDEQACCDNINRYNNYQNL
                     EITVLSADNLLEDFYHCFTSMSGQYICFCDCNHKYDSNRIRALLLLLSQNDSVDGVVCS
                     RNFIEADNTILAHPERIYREVLDEHIFGGNQLLTYSIENDVNIYGDLSTLLLSMDYVKT
                     VPFFECDIPDSMQQSALLYQLLYSAKVLYTYMPLVSAILTPALHDAELVHDFQKFLNIF
                     QNQLLEHTSATVNNFSQTENFVPCKKDITFFYTDMGEYYNLKPIADEAEARGYRVSFTR
                     DIFAPAEIGVYCQHVCHPENSRFSVILLHDLAQGHKPNIWEYEPWNKFDIGILPGKFWN
                     NLWSRCAFNYYVNPRCGTYEFGYPKSDLVSSPELAQRVSSLKEKLNLKYDISILYAPSW
                     ENDGKEDDFIKALSSLNVNLLIKQADWSEVYSNITENIRQMRELHEGKYENVYYIEPQE
                     SIMTALAMSDIIVSDESNVMAEALMFGKLSIAVADWLIPDCTPSRYANPMDYVIKTTKK
                     DLRKDVERFLSSPKYYSDFFEKGRELFSNAGNCCVEILDAIGYFTSDKHSTSTAFLKKR
                     MSSKYSICSLWN"
     CDS             9072..10145
                     /locus_tag="ctg30_12"
                     /transl_table=11
                     /translation="MCAGYNAGMQSSDAKYKVYLHHDVFIKESKFIFYLLERFCSAPDV
                     GMIGMVGGCGMPKTGVAYLAWNEGTVDCREPDFAYQLICDPAQQADCLVDAVDGLLIAT
                     QYDVAWREDLFVNFDFYDVSQSFEMRKAGYHILVPYQKTPWVIHDSSFAKLNHYDENRK
                     IALETYPDFFTEEDGFSFVYEEEWENLSEALADEVRRLIDVGNWEDAGKIIELYHKNQM
                     KNSALELYGVMCEIYEKEQECGIKEHFFDKTGDYEAACQKYITVRFLLRRVECEMESAA
                     YSELKDAVVEGRISAETLLLMILHGSYDKATVLRKVIPWCEAAGDNDGAQKLQAFYDRV
                     KGKKLPFAYSKRVSVKR"
     CDS             10177..11073
                     /locus_tag="ctg30_13"
                     /transl_table=11
                     /translation="MYKIAIIYAGATYESALNHIRLQELLGKIKVIGIGTQDIYAEYVD
                     GYPVTTIENILQQEWDYLLIAGQEQNFAQMKALLVSIGIEADRIFSIMVFSLPMFDMEE
                     YVQFVNKKVSIISNHCWGGFTYHSLKAEFLSPFINMFIPQADYIRLLESFDAYMNEKVK
                     YYKNEYESNLKREYPVALLGDIELHFNHYKSFEEAEQKWYERKQRMNEERLFVEMQTDS
                     EELAERFDKLPFKQKVVFVPFETKLTSAISLKKINANYSGAFYESVNRLATGQQAFYNI
                     LKLLNGERDFFRVSEKM"
     CDS             11143..11382
                     /locus_tag="ctg30_14"
                     /transl_table=11
                     /translation="MNLYEKMKSGIYVIAEMSANHAGKIENAFKIIEEAAKAGADCVKI
                     QTYTADTLTIDCDDSKYVIIRICQQLYFSDTLFS"
     CDS             11406..11744
                     /locus_tag="ctg30_15"
                     /transl_table=11
                     /translation="MKTDEKITLWSERIHEFQFSGQTCKTWCQEHHVPVSSMNYWMRKL
                     KKLDEQSDTDMIFAKMPTEKEISKNETLNISPSPVRIFITNAIRIEVMPECPPEFFRIL
                     IQGLKDHA"
     CDS             11953..12105
                     /locus_tag="ctg30_16"
                     /transl_table=11
                     /translation="MKRLDKDSFHWPDTPDELQKVTLKEMHWLCDGLSLTPKGAFEERH
                     PKIVV"
     CDS             12395..13897
                     /locus_tag="ctg30_17"
                     /transl_table=11
                     /translation="MNAMLSDRLALAQRRRFGSSSEKYADGYEQMDLFNEAEVNADTDT
                     AEIEEEIVIPSHKRKKRTGKKEEDLSNFEVTETIEYKLTGEDRYCPDCGTKYKVVTKEV
                     VKRLKFIPSTFEVVEEVTYVYSCPKCGAMIRPEKEFPLIKGSIATPSLVAGIMNAKYVN
                     GMPLARQEREFARYDLNLSTKTMANWIISCADRYLGLLYGQMKEEFLKSRYIHCDETRI
                     QVIDEPDQKGSSQNWMWVYLTDHYSEAPQMVLFDYERTRAGYHPVNFLGDTFHGYLTCD
                     GYQAYHGLNDSITVTGCFTHARRRFDAALTALKKDFTKEQLKETVAYQAMTRIGILYKV
                     EELIKDKTPEERYQERQKQSRPVVEALFEWLHSMEDSVDRSSLIGDAILYTLDQENYLR
                     RYLDDGHLSIDNNSAERAIKNFAVGRRNWLFAKSIRGADASAVVYSIAETALLNGLKPY
                     VYLSYVLDELRKMGPFPKPDDLNRLLPWSNELPEGFRTKKKK"
     CDS             14087..15067
                     /locus_tag="ctg30_18"
                     /transl_table=11
                     /translation="MQFTQDFFKPEIREEFEIQAMMKRAWAAQMEVLQVVADICEENGL
                     QYFADGGTLLGAVRHQGFIPWDDDIDICLKREDYNRLISILQRQLPYGFVMSGMYAGTV
                     RLRMAANVSHLRVIADETLWNFNDYMKYFHGFPYQRVGIDIFPLDYIPVEAKLADIQKI
                     MMIQGMNLLENWTTLEKAGKLEESLQEYEKLCNVRIDRQNTKNGLWKLTDAIASLCHKE
                     EAEYITNYIYWIEKDSYKMKKECYDEAVMLQFENIQIPVPAMYDEVLRAEYGGDYMTPV
                     QGAADHDYPFYGHMEEELKKQIKAVGFDGSVEEFCQEVSSGRLWV"
     CDS             complement(15192..17234)
                     /locus_tag="ctg30_19"
                     /transl_table=11
                     /translation="MKQPDKDLIESALQHSNMNLVETLLQDLHLIYPYDRDFYFYQCIY
                     FLTIKQYEQAQNIITDCLRKFPTSYECYYYQASIYQAQNMTLPALKNYEICAFLFDYFN
                     ADWNDIRTDANTQISILSSQLKILIDEYTEKKDLKGLLDIAAFFERRETIWGKNDSAPR
                     DPNNYVIGNKYYVSDTEARYIGIYRNPTHYVTKQIHNMSLVYNQGEFLKFHEYGVSSYI
                     NGNAKEYLLPIAVETPNTIHKIQNGDITYTILQRIPQHFNYYRIPNRVHINSSNKAYYG
                     EPIALGHSSKRKKLVLSLFVDGLTQEIIQGSHLKERMPNTYRFFSKGIICSQAYSTAEW
                     TFPSLASYETGLDTLNHMLFHNNLNNELPYDFPTLSEYFKEQGYFTSKLDGDWRSTYSC
                     GYTRGIDQYIYQHQLLGARAEQEIINIIEHLEAFKDTDHYLWMCIGDLHDVADELDLSP
                     AMQNNLALKYRTYEKQSKTSVKQSYSENKSETYKKMVTYIDTLLELLYSYIENNYKNTE
                     ILISLFADHGQGYLVPSDKPFLSKERSHVAFMFRSSDLNPCCTDEIISSTDYLPVMCKL
                     AGISQSDAPINGQLPKIFGGQTEREYAITESLHPGDPYCAVAHTRNFEIFFDNPIPADD
                     EGRFTLGNYSVYGFFNSGEPITDSELLKKYEHIFISRIAMHIIYD"
     CDS             17315..18253
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_20"
                     /sec_met_domain="APH (E-value: 1.2e-09, bitscore: 29.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKLKQDKLLDEEALTVICEALHVNNQDITDIDIMKKGMTNRSFT
                     FRCKGKRYMIRISGVGTEKLIDRCQEKEVYEAIRDMDICDPVIYIDSEKGYKISEFLEN
                     SRVCDPMNGLDVKRSMECLKRFHDKKLAVGHTFDLFGQIEKYELLRGNSKSVYADYEKT
                     KRDVYWLKSFIDRNIEEKVLTHIDAVPDNFLFVKDEYGKEQIKLIDWEYAGMQDPHVDI
                     AMFGIYSLYDREHMEQLIDAYFPEGCSKRIRTKIYCYIAVGGLLWSNWCEYKEKLGNSF
                     MEYATHQYQYAKEYSYIALLKLQEMERTLHA"
     CDS             18246..18971
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_21"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.3e-15, bitscore:
                     48.3, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHKVERAIILAAGIGKRMNPVTLGTPKPLVKVNGVRMIDTIIKAL
                     YQNDITEIYIVVGYLKEQFCEIRKEYQGITLIENPYYATCNNISSLYVARKYLENAIIL
                     DGDQIICNERILISEFCRSGYNSVWTFEETDEWLQTVKDGIVTACSRVGGGCGWQLYSI
                     SRWTAEDGRKLKKHLELEFEQKHNTQIYWDDIVMFCHSQEYQLGIFEMQPDDVIEIDSL
                     EELISIDNNYVKYREKGLA"
     CDS             18968..20509
                     /locus_tag="ctg30_22"
                     /transl_table=11
                     /translation="MKKKEREQIDWLITIVPFLLIISLFVLFIILPEQSNYILGRIRFF
                     LGDTFGSYYIMIGIVFFCVSIYLAGSKYGNIILGTQGEKPKNSFFSWGAMMFTCGLAAD
                     ILFYSFSEWMMYASDPHIIELGNIQKWAGIYPLFHWSFIPWSFYLVLAVAFGFMLHVRN
                     RERQKYSEACRPILGKQTDGIGGRMIDLLAVFALIAGTATTFGIATPLISEILTDVFQI
                     QLERTALNLIILIITCLIYTYSLLHGFHGISFLAKICIYMFFGILLYVLLFGGKTRYII
                     ESGISSLGIMMQNFISLATDTDPLRTSYFPQNWTIYYWAYWMVWCVASPFFIGRISKGR
                     SIRQVILGGYMFGAGSTMVSFIVLGNYSMEMQMSGTVDYVGEYNRTGDLYHIIVSIIKT
                     LPGATIVLLAVVFTMIAFYATSFDSIALIASCYSYRKLDGQKQPHKVVQLIWCILLILF
                     PIALLFTNSSMSNLQSVSIIAAFPIGMVMILIVISFFKDVEKYKKDLDNSQKQTK"
     CDS             20554..22584
                     /locus_tag="ctg30_23"
                     /transl_table=11
                     /translation="MVTRCVMKNDKKEKIWDLFDQKENANDIQTMILEYENEFSDDMDI
                     FLMKMCLFIYENKIQAAIEIGKQALRKNPYLLEIHLKLAEAYKDQSKYIEAYKHYCISK
                     LLASFAGEEKICRDCELLAKGSLEQLEELITYLPDEQKIYLSQKMIPAFLGYEKNQFGY
                     NERRFRTFEHIGGDYYYESEEVKKYVGMYHRPRHVINELDAVHWKIEFQEVVEANYLKL
                     PDTEKKWIVPVAVEKNTTHWFETDNGKMPVIQRDIKSFYYYRVGGGREIISSDICYWGN
                     PIPIKSDKNKKRLVLSIFVDGLAQVLLTADKFAYLMPNTAKFFKNGMVCKQAYSSGEWT
                     YPSIAGVMSGLATTQHMMFHNEIDWKLPNSVKTLMEYFHESGYYTSAFSGDWRIIPSYG
                     YARGCDRFIYQLQHTGFSVEKMIGGVINEIDALKEINQFVWVSLGDLHDVADEMELPTS
                     VQTHLKIEDRVCEKGSETSVKQKYDMAKKIQYEQMLQYMDRYLGMLFSYLENTYEENEL
                     IVALFSDHGQGFLIPEDGQFLGPERTNIAFMFRNGQLKGETEEVMSSLDYTAILCKMAG
                     IAYCEQGVEGRTPRIFGGSGRRWALTESLHPKDYYRAALVSENYRFYFCNPIPVGYDGR
                     FEIGDYSICLTDKEGRNVYAEDVEKECLDIIMRQIANLCIY"
     CDS             22625..23749
                     /NRPS_PKS="Domain: Aminotran_5 (25-292). E-value: 4.3e-39.
                     Score: 126.3. Matches aSDomain:
                     nrpspksdomains_ctg30_24_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 84.9; E-value:
                     8.7e-26)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_24"
                     /sec_met_domain="Aminotran_5 (E-value: 1.2e-37, bitscore:
                     121.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRNILLNPGPATTTDTVKQAQVVPDICPREQEFVEIMKQIRKDL
                     VKIVHGDEQDDTSVLFCGSGTISMDVCLNSLLPEEKKILIINNGAYSSRAVEICEYYGM
                     PFINLEFPIDERPSLELIEQVLKENNDIALVYTTHNETGTGILNPVREIGALVHRYGAV
                     FVVDTTSTYAMRPIDIKKDNIDFCMASAQKGLMAMTGVSFVIGNKSIIERSKDYPKRSY
                     YCNLYLQYDYFEKHGEMHFTPPVQTVYAMRQAIAEYFAEGEQEKWKRHTRVYDALYSGL
                     ERLGFQNVIKKEWQAGLVAAVKYPDDPNWSFSAIHDFCYERGFTIYPGKINNTETFRLC
                     ALGAIDETDIEDFFEIFEEGLKQMGVSLPVYYQK"
     aSDomain        22700..23500
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg30_24_Aminotran_5.1"
                     /evalue="4.30E-39"
                     /label="ctg30_24_Aminotran_5.1"
                     /locus_tag="ctg30_24"
                     /protein_end="292"
                     /protein_start="25"
                     /score="126.3"
                     /tool="antismash"
                     /translation="DICPREQEFVEIMKQIRKDLVKIVHGDEQDDTSVLFCGSGTISMD
                     VCLNSLLPEEKKILIINNGAYSSRAVEICEYYGMPFINLEFPIDERPSLELIEQVLKEN
                     NDIALVYTTHNETGTGILNPVREIGALVHRYGAVFVVDTTSTYAMRPIDIKKDNIDFCM
                     ASAQKGLMAMTGVSFVIGNKSIIERSKDYPKRSYYCNLYLQYDYFEKHGEMHFTPPVQT
                     VYAMRQAIAEYFAEGEQEKWKRHTRVYDALYSGLERLGFQNVIKK"
     CDS             23768..24055
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_25"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.2e-13, bitscore:
                     41.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKEKDEIAILMAAGLGTRMRPLTEQIPKPLVPVMGTPLIETVIC
                     ALERRGIKRIYVVVGYLKEQFSYLLEKYDNLEIVENKEYLKKTIFRHCMQ"
     CDS             24052..24480
                     /locus_tag="ctg30_26"
                     /transl_table=11
                     /translation="MRDILGSSDCFICEADLYVPDDTIFLRQYSTSCYFGKMIEGYSSD
                     WVFDVQNGNITRVGKGGTDTYNMAGISYWKRSDALIIKKAIEASYKKPGHEKLFWDEIV
                     DQELKRLKVQVEEISPESVIEVDTLEELSQLDSRYKTC"
     CDS             24474..25607
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 46.8;
                     E-value: 3.1e-14)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_27"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5e-22, bitscore:
                     69.8, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.6e-15, bitscore:
                     47.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVTDFVEQIKKIGIKTLAGVPDSALKSFCDYINGTGKNEFEHYV
                     PVNEGAAVGIAIGSYLATGVPACVYMQNSGLGNIVNPITSLANKDVYGIPMLLLVGWRG
                     EPGTKDEPQHKYMGKITEDLLRVLEIEYIVLEKELSMQEIMRSFERAAQVLKEGKQFAF
                     VLKRDFLQNNNSSDYKNNNSLVREDAIAAIIKMLDESDVVISTTGKISREVYEQSDRIK
                     GSHAQDFLTVGGMGHASMIALGMAHKLEKKRVYCLDGDGAVLMHMGSMAYIAKQKPQNL
                     IHICLNNDAHESVGGMPTGCVGLSYADIAGTVGYERVYCVDKQQDLTKVLSDIKKKRNL
                     TFIEIKVAMQSRADLGRPKETAEENKNNFMKYHGVGL"
     CDS             25604..25693
                     /locus_tag="ctg30_28"
                     /transl_table=11
                     /translation="MKKVYACFCTDVIHEGHLNIIREAKNMEN"
     CDS             25720..26898
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 206.3;
                     E-value: 9.2e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_29"
                     /sec_met_domain="CTP_transf_like (E-value: 2.3e-08,
                     bitscore: 25.8, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 5.1e-117, bitscore:
                     381.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.1e-65, bitscore:
                     213.0, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRYNRFPTVSFEERKKMLEQIPEVDEVVVQDEVMYGSILERIKP
                     DYVIHGDNWLNDPMEVIRDNVIENLKKWGGQLIEIPYTYNEQVRNIEAVMRERTAMPEY
                     RRKRLRQLLQLCPIVKTLEVHSGLTGLIAEKTVVANNGEIDQFDAMWLSSLCDSTAKGK
                     PDIELVDMSSRLRTVDDVLEVTTKPIILDGDTGGMIEHFVYNVRTLERVGVSAVIIEDK
                     TGLKKNSLFGTEVEQTQDSIENFTAKIRAGKRAQRTKDFMIIARIESLILEKGLEDALV
                     RAFAYVDAGADGIMIHSRKKTPDEIFAFCDRFREKDKITPLVVVPTSYNETYESELQQH
                     GINIVIYANQLTRSAFPAMQQTATDILRYHRAKEVDDRLMSIKDIITLVDEV"
     CDS             complement(27046..28059)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_30"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.4e-33,
                     bitscore: 107.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVSVIIPCFNATKYLPKCFMSLVQQTIGIDQIELIFVDDASTD
                     EDATWNMLQEFERAYPESIMILKLEENMRQGGARNVALQYATGEYIAFVDADDFVAENF
                     LLETYEKAKESDADIIQFEYFYYTDRLGAVDSGRNIMPEVIEISSVNDRKEFLISEKIT
                     YGCWNKLYRHDLLKTAHTAYAEHVIYEEPLFVYPLLYFANKIVILNDAYYYYRQNDSGT
                     MRNDMRQEETLKMHADVQLAVWNFMKNTPFFQEYYDEIKLYFLHTYLYETLYFAKLRDF
                     KPSYSFYKELEKTVFTEVPDYSQSVYSALIPKQLELYRMIEEGMTEEKFGGYCERL"
     CDS             28180..29892
                     /locus_tag="ctg30_31"
                     /transl_table=11
                     /translation="MSGNIAIGIQDFSTIIQGNYFYIDKTPFIKEWWDCGDSATLITRP
                     RRFGKTLTMSMVEQFFSIDYAGRSDLFEHLAIWKEEKYRELQGTYPVISLSFARIKERD
                     YEKTKQKMCEVLRNIYIKFCYIKDSEKLTDADRAYYERMLEENIKETDATSSLYQLSDF
                     LYRYYGKKVIILLDEYDTPMQEAFVDGYWDELVAFTRSLFNSTFKTNPALERGIMTGIT
                     RVSKESVFSDLNNLKIVTTTSNEYASVFGFTEKEVFDALEQYGLEKEKKEVKRWYDGFI
                     FGEHKDIYNPWSILNYLDTQLYKTFWANTSANSLVGKLIQEGNRTIKEKFEKLLCGECI
                     WSEIDEQIVYNQLNGNEKAVWSLLLASGYLKVLSYETYQDIEEGKMPKYQLALTNLEVK
                     LMFQGMVHDWFAPVQPDYNDFVKAMLLDDVDAMNEYMNRIAIQTFSYFDTGERASGAEP
                     ERFYHGFVLGLLVDLRDRYHLKSNRESGFGRYDVMLEPKNSKECNAVILEFKVRNPRKE
                     KSLQETVLSALKQICEKKYDADLLDKGIRQEQIYHYGFAFEGKKVLIGTDREE"
     CDS             29937..31088
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_32"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6.3e-20,
                     bitscore: 63.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVCIITKNEEHNIARCLKSFQKTGFELIVADTGSTDQTKKIAA
                     EYTENIYDFPWCDDFSAAKNFAVSKAAHPYVMVIDSDEYLQQIDRVQLEKMIAEHPGEV
                     GRIRRINIISGKDGKQENKEWINRIFAKESFHYTGRIHEQVTACDEKEYRTYEAPVVIG
                     HTGYDLPKKEKKAKALRNIRLLEQELKNSGWDAEAHATQLDQNIAKQDTDAEQKSKITD
                     AKKEQQIPYLLYQLGKSYYMAEDYNEACFWFAHGLSYDLEPKLEYVIDMVETYGYALIN
                     SGRAGEALFFENIYEEFGNSADFQFLMGLIYMNNAMFDAAVGEFLKAVKHRDCRMAGVN
                     SYAAYYNVGVIYECLEKISEAKYYYQKCGGYEPAKKRLRLINS"
ORIGIN
        1 acggcaataa cagccagaaa tatttaacta aatatcaata tgtcagtaca ctagatgttg
       61 catgcggaat tggaagatgg gcagatgctt tgccagaaga tattaaagag tattgtggta
      121 tggattttag tgaagaattg gtagcaattg cgaataaaag aaatcataga aacagatttt
      181 tttactgtgt aggtggtgcc aatgaaattg cagcggtact gaaaaaaaat ggaaagggtt
      241 tgtataacag gattttgatc gttggaattt taatatattt gaatgatgta gatatggcag
      301 attcattaag acagatagaa aaagtttgtg agacaaaatc cgttatatgt atccgggaac
      361 ctattgcaat agaagaaagg ctcacattaa aagatttttt ttctgaggaa ttgaacgatt
      421 attataatgc tatatataga acacgggatg aattgatggt aagtataaat gaaatgttct
      481 taaataaagg attcaggata aaagaggaag gatttttatt tgatgacgat gcgcttaaca
      541 atagaaaaga gaccgctcaa tattactata tcttggaaag gtgaccaaac atgtataggg
      601 aaaaggtagg gattataggt ggctttgggg catatgcaac gttaaatttt tataaaagat
      661 tgttggaaga attcgcttca gaaagtgaac gaaattatcc tcatataata atggataata
      721 attttaccat gccaagcagg acaagggcat tattgtatgg tgaggcatat gatgaggtgg
      781 tggatggtat ttctgattcc atacagttaa tgatgcagaa tgatgtgagc aagatcatat
      841 tagtgtgtgg aacagcgcat tattttttaa atgatgtata taaaaaattc cggaggcaaa
      901 agaaaaaatt gtagacatta ttaatattat ggtcgaagaa ctgaaattga aggatgaggg
      961 agaagtgttg gttattgctg cggagggggc gttacagaaa aaattatatc aaacacgttt
     1021 aaaaaagtat ggaataaaat gtgtaaatcc agatgaagag gattttatag atattcggta
     1081 tttcattgaa tgtgtgaaaa gaaatgaatt gaatgaagat ttagtgcatc agtttggaaa
     1141 ttttcttgac aaatttggca aaagaaatgt ggttttaggg tgtacagaat ttccagtcct
     1201 ggtagaatat attgataaat gccaaaaaac agagagtaca gtaaatttac gaaaacaata
     1261 ttgcttttac gatccactac agatgacgat aaagtggttg aaagaaaatt tacaatagca
     1321 aaagagaggt agaggatgag cagatatatt tttctattcg atttggattc aacggtaacc
     1381 aaacaggaaa tattgcctac tatttcaaaa aggctaggaa tatatgagag gatgagcgaa
     1441 cttacagaga gtacaatgag gggggaaata ccgtttaaac agagtttttt gcaaagggtt
     1501 gaactattga aagatgttcc tgtaagtgaa gtgaatgaaa tggtcagcag aattcaatta
     1561 aacaatcatt tagtggattt tatacagaaa aatcacgata gatgccatat tgttacaggg
     1621 aatttggatg tatggattga tggggtgatc aggaagttgg gaatggaacg aaatacgttt
     1681 tgttctaaag cgattgtgaa aaatgattat attgaagacg tgtttaatat tgtagacaaa
     1741 aatgcggtta ttggtcaaat ggttttacca tttgttgcaa ttggagatgg aaataatgat
     1801 gctgagatga tagaggcagc ggaagtagga attgggtatg gtggggtaag ggagattgca
     1861 ccggcagtac ttgcatgtgc cagtcatgca atttatgatg aggaaaaatt agtcgaattt
     1921 ttagaaaggc tcttgtaaag gaggaaatgc aatgcaggtt tcgaggacag taatcattag
     1981 ctgcgcaggc atggggaatc gtttggggct tggaactaca aaagcactgg ttgaagtaga
     2041 aggtaaaccg ttaattatgc atcatcttga aaagctgaaa gatgagagtg atattcgtgt
     2101 agtagttggt tatcaggcag aaaaggtaat taatgtagtt agaaaatatc gaaaagatgt
     2161 tgtgtttgta tttaaccata attatagaga aacaggaaca ggtgcaagtg ttgcgttagc
     2221 atcacaatat gcaaatgagt atattttatc tttggatgga gatttaataa tacatcctga
     2281 tgatatgaaa aaaatattgg aatgtgatca tgaatttgtg agtggaggaa taccggatac
     2341 agatgagccg tggatgcttc agacatacaa agatgatggt aaagagtttg taagtgcatt
     2401 ttcaaagaat attggcaatt atgaatggaa tggcattaca caaatgaaga gcgcaaagat
     2461 caaaaatgga caaggacatg tttttcagtt aatagaacca tatttgccaa ttccgttttt
     2521 ggaacttaga acacgcgaaa ttgatacggt aaatgattat gaaagagcgg ttgagtgggt
     2581 tagaaataat ttcagggaat aagatgtatg caacgtattt gaaggagaaa acaacgtgaa
     2641 aagaaatata ttattaaatc cgggacccgc cacaaccact gacacggtaa aacaggcaca
     2701 gatagtgccg gatatttgtc cgcgggaaca ggaatttgtt gagataatga aacagatccg
     2761 cacagatctg gtcaaaatcg tacattgaga tttagaggaa tatacatctg tattattctg
     2821 cggttcggga acgatttcca tggatgtatg tttaaattcg ctgttgccgg aggaaaagaa
     2881 aatactggtg gtcaataacg gtgcatacag ttcaagagcg gtcgagatct gtaaatatta
     2941 cggactgccg tttattgatc tgaaatttcc gattgatgag agaccatcgt tggaagtaat
     3001 tgagcgtaca ttaaaagaaa acgaggatat tgcccttgtc tatacgacgc acaatgagac
     3061 aggtacggga attctgaatc cggtacggga gattggggcg ctggtgcatc agtatcatgc
     3121 agtatttgtg gtagatacaa catccaccta tgcgatgcgt ccgatcaata tcaaagaaga
     3181 taatattgat ttttgtatgg catccgcaca gaaaggtctt atggcaatga caggagtatc
     3241 ttttgttgtc ggcaaaagaa gtattattga acagtcaaag gattatccaa agagatctta
     3301 ttattgcaat ttatatctgc aatatgatta tttcgaaaaa catagagaaa tgcactttac
     3361 cccaccggta cagactattt acgcgatgcg gcaggcacta aaggaatatt ttgcagaggg
     3421 tgagcaggaa aagtggaaac gtcataccag agtttttgtg gccttacatc agggattgga
     3481 agagctggga tttcaggatg tgataaagcg ggaatggcag gcaggactgg tcattactgt
     3541 aaaataccca gatgatccaa actggagttt ttctgcaatc catgattatt gctatgagag
     3601 aggatttacg atatatcctg gaaaaatcaa caatacggaa accttccggc tttgtgcgtt
     3661 aggtgctgtt gatgaagctg atatccagga gttttttaaa gtatttcaag caggattgga
     3721 aagcatgaaa gtggcggttc ctgtttttta ccgtgaagaa aaataaaagg atcagattat
     3781 gaggtgatat gcaatatggc agataacgag attgctattt taatggcagc gggacttggg
     3841 acaagaatga gacctctgac agataaaatt gccaagccat tggtaagtgt tcatgggaaa
     3901 tcactgattg aaacaattat tgaagcgttg cagcagcgtg gtgtcacaat aatttatgtt
     3961 gttgtaggat atcggaaaga gcagtttgct tatttaacag aaaaatatga tcatttggta
     4021 ttgattgaaa ataaggagta tctgaaaaaa aataatattt catcactgta tgctgtgggg
     4081 gatattctgg gaagtaagga ctgttttatt tgcgaggcag atctgtatgt gacggatcct
     4141 gcaatttttc tgaggaaatt taagaaatcc tgctattttg gaaaaatgat tccgggatat
     4201 tcggatgact gggtatttga aatacgggaa ggaaaaatta ccagagtcgg aaaaggcggc
     4261 acggatactt ataatatggc aggaatctcg tattggaaaa aggaagatgc cgtgttaatc
     4321 aggaatgcca ttcaagaagc atataaaaca gcaggacatg aacagctttt ctgggatgag
     4381 atcgtggatc aggaattgga caatcttgat gttacggtag aagagatacc ggcagatagt
     4441 gtggttgaga ttgatacatt tgacgaatta tgtaaaatag atgagacata ccgtaatgca
     4501 gaatagatgg gagaagagaa atgattgtaa cggattttat aaaacagatc aaaaaagtgg
     4561 gaattaaaac attgacaggt gtaccggatt ctgcactaag gccattctgc gattatatca
     4621 atggagtggg gaaagaggaa tttacacatt atgtaccggc aaatgaaggg gcagcagtcg
     4681 gtattgcaat cggagaatat ctttcgacgg gcgtacctgc ctgtgtatac atgcagaaca
     4741 gtggacttgg aaatattgtt aatccgatca catcgcttgc aaatgaggaa gtatacggaa
     4801 tcccgatgct gttattggtt gggtaccgcg gtgagccggg caaaaaggat gaaccacagc
     4861 acaaatatat gggtaagatc acagaaagcc tgctggatgt gcttggcata gaacatatgg
     4921 tgcttgggaa agaactcacg gagcaggaga tttcagaggg ctttgggaga gctgcacaaa
     4981 agttaaagga agggcagcag tttgcgtttg tcctgaagaa ggatttcctt gagattgaag
     5041 aaaaaagtat ttatgtaaat gacaattcac tgatccggga agatgttatt gcacagatta
     5101 tagagtcact ggatgaaagc gatgttgtgg tttctacgac tggaaagata tccagggagg
     5161 tatatgaaca gagtgacaga atcaacggaa gccatgcgca ggatttcctg accgtaggcg
     5221 ggatgggaca cgcatccatg atcgcatttg gaattgcgga gaatgcaaaa gaaaaacggg
     5281 tgtactgcat ggatggtgac ggagcagaac tgatgcatat gggaagtctg gcatttattg
     5341 caaagcagaa accgcaaaat tttgtccata tctgtctgaa caatgaggca catgaatcgg
     5401 ttggaggaat gccgaccgga tgcgtagggt tgagttacgc agaagttgcg cggacagttg
     5461 ggtacgaagc tgtttactac attgatacaa tggaagaact aaagcaggtt ttgcatgaca
     5521 ttaaaccaga aagaaaactt actttcattg agataaaggt ttccatgcag tcaagagcgg
     5581 atctgggaag accaaaagaa acagcagcag aaaacaaaga gaattttatg aaataccacg
     5641 gagtgaaaga atgaaaaaag tatatgcatg tttttgtaca gacgtgatcc acgagggtca
     5701 tctgaatatt attcatgaag caaaaaaata tggaaaagta attgcgggtg tattaagcga
     5761 tgctgcgatg atacgttata accgttttcc tactgtttca tttgaagagc ggaaaaagat
     5821 gttagagcag attcctgagg tggatgaagt agtagtacag aatgaggtca tgtacgggaa
     5881 tattttagag cagataaagc cggattatgt cattcatggg gataactggc tgaatgatcc
     5941 gatggaagtg atccgcgata atgtaatcga aaatctggca aaatggggtg gccaattaat
     6001 cgaagttcca tatacatata atgagcaggt aaaaaatata gaggcagtga tgcgggagcg
     6061 cgctgccatg cccgaatatc gcagaaaacg gctgcgccag ttacttaaat tatgtcctat
     6121 cgtaaagact ttggaagtgc atagtgggct gactggtctt atagccgaaa aaacggttgt
     6181 ggcaaaccag ggggagatcg atcagtttga tgcaatgtgg ctttcaagtc tgtgtgattc
     6241 cactgcgaaa ggaaaaccgg atattgaact ggtagatatg tcgtcaagac tgcgtaccgt
     6301 agatgatgta cttgaggtga cgacaaagcc gatcatttta gatggtgata ccggcggaat
     6361 gatcgaacat tttgtataca atgtgcgtac attggaacgc atcggcgtct ctgccgtgat
     6421 catcgaagat aagacaggat taaagaaaaa ttctttgttt gggacagagg tagagcagac
     6481 gcaggacagc atcgagaact ttactgccaa gatccgcgca ggaaagcatg cacagcgcac
     6541 acaggatttt atgattattg cccgcattga gagcctgatt ctagaaaagg gtatggatga
     6601 cgccttagag agggcatctg cctatgtgga agcaggtgca gatggaatca tgatccacag
     6661 caggaaaaaa gaaccggatg aaatctttga attttgtgat aagtttcgta atagggatgc
     6721 ggtaacaccg atcgttgttg tgccaacctc atataatgcc acctatgaga gtgagttgca
     6781 ggcacatggg gtcaacattg tgatttatgc aaatcagctt acgcgcagtg cgtttgcagc
     6841 aatgcagaaa acagctacag atattctgac atatcacaga gcgaaagaaa tcgatgacag
     6901 attgatgcca attaaggaga ttattacttt gattgatgag atttaggtat tgtagaatat
     6961 gcttgtggac agactgacat tacagaaaat tgacgatata gggagaaata ttatgaacga
     7021 tatgtctatt aaagaacaaa tgatgcagtt aacaaaacaa tgtattttat ctaacgatga
     7081 taaagctatg cttgaatgtc tgcaaattta caaatcatct tttggctatg atgattttta
     7141 tattactagt ttatcttctt tgcgtattac accagagcca ttggtaagcc ttatttacat
     7201 aaaacagccg gatgaggatg aacaagcatg ttgtgataat atcaacagat acaataatta
     7261 tcaaaatctt gaaattacag ttctgtctgc agataatttg ctggaagatt tttatcattg
     7321 ttttaccagt atgtcaggtc aatatatctg cttttgcgac tgtaaccaca aatatgacag
     7381 caaccgtatt cgggctttgc ttttactact tagccagaat gattctgttg atggagtcgt
     7441 ttgcagtcga aattttattg aggcagataa tacaatcctt gcacatcctg agcgaattta
     7501 ccgggaagta cttgatgaac atatttttgg tggaaatcag ttattaactt atagcattga
     7561 aaatgatgta aatatatatg gcgatttatc taccctgtta ttatccatgg attatgtaaa
     7621 aaccgtgcct ttttttgaat gtgatattcc tgattcaatg cagcaatcag cgttgctgta
     7681 tcagttactt tattcggcta aagttttata tacctatatg ccattagtat ctgctatact
     7741 gacacccgct ttgcacgatg ccgaattagt tcatgatttt caaaaatttt taaatatctt
     7801 tcaaaatcag ttactggaac atacatcagc aacagtgaat aattttagcc agacagaaaa
     7861 ttttgtccca tgtaaaaagg atattacatt tttttatacc gatatgggtg aatattataa
     7921 tttaaaaccg attgcagatg aggctgaagc ccggggatat agagtgtctt ttaccaggga
     7981 tatctttgca ccggcagaaa ttggtgttta ttgtcagcat gtatgtcatc ctgaaaattc
     8041 aagattttct gtgattcttc tgcatgatct ggcacaggga cataaaccaa acatctggga
     8101 gtatgagcct tggaataagt ttgacattgg gattcttcca ggaaaattct ggaataatct
     8161 gtggagcaga tgcgccttta attattatgt caatccaaga tgtggaacat atgaatttgg
     8221 ttatcctaaa agtgatttgg tatcgtctcc tgaacttgca cagcgtgtta gcagtttgaa
     8281 agaaaagtta aatttaaagt atgatatttc gatactttat gcaccatcat gggagaatga
     8341 cggaaaagag gatgacttta ttaaggcatt gtcttcttta aatgtgaatt tgcttatcaa
     8401 gcaggccgac tggtcagagg tgtattctaa tattactgag aatatacggc aaatgcgaga
     8461 acttcatgag ggtaaatatg aaaatgtata ttacattgag ccgcaggaaa gtatcatgac
     8521 agcacttgca atgagcgaca ttattgtttc tgatgaatcc aatgttatgg cggaagcatt
     8581 aatgtttggt aagttaagta ttgcggttgc tgattggctt attcccgatt gtacgccaag
     8641 cagatatgcg aatccgatgg attatgttat taaaacaaca aaaaaagatt taagaaaaga
     8701 tgttgaaagg tttttgtcat ctcccaagta ttattctgat ttttttgaaa agggaagaga
     8761 acttttttca aatgcaggaa actgctgtgt agaaattttg gatgcgattg ggtattttac
     8821 atctgataaa cacagtacat cgactgcttt tttgaaaaaa agaatgtcat caaagtattc
     8881 tatctgcagt ctgtggaatt agtgatagtg gagataagag tggagaagaa tacatgaatg
     8941 aaaataaaat cgcatttatc atatgcacga acaatcaatt atattttaat gagtgctgct
     9001 actacataaa caggctgctt ctgccggaag gattcgagcg ggatgtcatc ggcattgagg
     9061 atgcaccatc gatgtgtgca ggatacaatg ccgggatgca gagcagtgac gctaaatata
     9121 aagtatatct gcaccatgat gtgtttatca aagaatcgaa gtttattttt tatctgttag
     9181 agcggttttg tagtgcaccg gatgtcggca tgattggaat ggtcggcgga tgcgggatgc
     9241 ccaaaaccgg agttgcttac cttgcgtgga atgagggcac tgtggattgc agggagccgg
     9301 attttgcata tcagctcatc tgcgacccgg cacagcaggc agactgtctg gtggatgcgg
     9361 tggacggact tttgatcgcg acacagtatg atgtggcatg gcgggaagat ttatttgtga
     9421 actttgattt ttatgatgta tcgcagtcct ttgagatgcg taaagcagga tatcatatct
     9481 tggttcctta tcagaagaca ccgtgggtga ttcacgacag tagttttgca aagttgaatc
     9541 attatgatga gaatcgaaaa attgcacttg aaacgtatcc ggattttttt acggaggagg
     9601 atggattttc attcgtctat gaggaggaat gggagaatct aagcgaggcg ctggcagatg
     9661 aggtgcgcag actaattgat gtggggaatt gggaagatgc tggaaaaatc atagagttgt
     9721 atcacaaaaa ccagatgaaa aattctgcgt tagaactgta tggtgtaatg tgtgaaatct
     9781 atgaaaaaga gcaggagtgt ggtataaaag aacacttttt tgataagaca ggtgactatg
     9841 aggcagcctg ccagaaatac ataaccgtaa gatttctttt gcgccgggta gagtgcgaaa
     9901 tggagagtgc ggcttattca gagttaaagg atgcagtggt ggaaggaaga atttctgcgg
     9961 agacacttct tttaatgatt ttgcacggaa gctatgataa ggcgacagtg cttcgaaaag
    10021 tcatcccatg gtgtgaagca gcgggagata atgacggtgc acagaaactg caggcattct
    10081 atgacagggt aaaaggaaag aagctgccat ttgcatacag taagcgggtt tctgtaaaac
    10141 ggtgaagaaa atatacaatg ttcgaagaga gaaaaaatgt ataagattgc aattatttat
    10201 gcaggtgcaa catacgagag tgcgttaaat catataagac ttcaggaatt gctcggaaag
    10261 ataaaagtta ttggaatcgg aacgcaggat atctatgcgg agtatgtaga tgggtatcca
    10321 gtgactacca tcgaaaatat tttgcaacag gagtgggatt atcttttgat tgcaggtcag
    10381 gaacagaatt ttgcacaaat gaaggcattg ttggtaagta tcggaataga ggcggacaga
    10441 attttttcga taatggtatt ttcgctgcca atgtttgaca tggaagaata tgtgcagttt
    10501 gttaacaaaa aggtaagcat catatcaaat cattgctggg gtggttttac ttatcattcg
    10561 ctgaaagcag aatttttgtc cccatttatt aatatgttta ttccacaagc agattacatc
    10621 agactgttag aaagttttga tgcttatatg aatgaaaaag taaaatatta taaaaatgaa
    10681 tatgagtcaa atttaaaaag agaatatcca gtggcattac ttggtgacat agagcttcat
    10741 ttcaatcact ataaatcttt tgaagaggca gaacaaaaat ggtatgaaag aaaacaacgg
    10801 atgaatgagg aaaggttgtt tgttgaaatg cagacggata gtgaagaact ggcagaacga
    10861 tttgataagt tgccgtttaa acaaaaagtg gtattcgttc cgtttgaaac aaagcttaca
    10921 tcagcaataa gtttaaagaa aatcaatgca aactattcgg gtgcatttta tgagagtgta
    10981 aataggttgg caacaggaca gcaggcattt tacaatattc tgaagttgtt aaatggagaa
    11041 agagatttct ttagggttag tgaaaaaatg taagcagtga atgatttgaa aaaatgccga
    11101 tattatattc agaaaagtga ataaatgcat aaaggagcag ctatgaattt atatgaaaaa
    11161 atgaaatccg gcatttatgt tattgcggag atgtctgcaa accatgccgg aaagattgaa
    11221 aatgcattta agattattga ggaagctgca aaagctggtg ctgattgtgt aaagatccag
    11281 acttatacag cggacacgct cacgattgac tgtgatgaca gtaagtacgt aatcatccgt
    11341 atctgtcagc aactatattt ttctgataca ctcttttcat aacaaagaaa ggaaactgta
    11401 tcattatgaa aacagatgaa aaaatcacac tgtggtctga aagaatccat gaatttcaat
    11461 tcagtgggca gacttgcaaa acatggtgtc aggaacatca cgttccagtc tcttcaatga
    11521 attattggat gcgcaagctg aaaaaattgg acgaacaatc agatacagat atgatttttg
    11581 caaaaatgcc aacggaaaaa gaaatttcaa agaatgagac tttgaatatc agcccatctc
    11641 cagtccgcat ttttatcaca aacgctattc ggattgaagt gatgcctgaa tgcccgccgg
    11701 aattttttcg tattctgatc caggggctga aagatcatgc ttgatctggc aggtggcaca
    11761 accgtttacc ttgcctgtgg agctaccgat ctgagaaaaa gctatcacgg actggctgca
    11821 attatcaagc taaaattcaa acttgatccc tattcgcgct gcatgtttgc gcgctgcatg
    11881 tttgcgttct gcaaccgcag gcggacttct attaagattc tgcaatggga cggatccggt
    11941 ttctggattc tgatgaagag gcttgacaaa gattcctttc actggccgga tactccggat
    12001 gaattacaga aagtgaccct gaaagaaatg cattggctgt gtgatggtct ttcacttact
    12061 ccgaagggag cttttgaaga aagacatcca aagattgttg tataaagaac ggatttgtca
    12121 attcgcaaaa agcacgaaat acttgtggat atcggtatat attcctacac agtaaaacgt
    12181 tgatttttct cgaacagctg gactttctat gctatactgg aattatcata taagagtttg
    12241 gagattgccg gatggatccg ttttttacag aggaacagct gaataacatg agccgtgaaa
    12301 acatgatgga agttatgaga atcatgcaga atcaggttca aaaaaagaga ccgaggtaca
    12361 gcttctgaaa gacaagcaga aagaactgga atttatgaac gcaatgcttt cagaccgtct
    12421 tgcgcttgca caaagaagac gtttcggttc ttccagtgaa aaatacgcag atggatatga
    12481 acagatggat ctgtttaatg aggctgaagt caatgcagat acggatactg ctgagattga
    12541 agaggaaatc gtgattccat cgcacaaacg gaaaaaacgc accggcaaaa aagaagaaga
    12601 tctttctaat ttcgaagtaa cagaaacaat cgaatataaa ctgaccggcg aagaccgcta
    12661 ttgtccggac tgtggaacaa agtataaagt cgtcacaaaa gaagtcgtaa aacgactgaa
    12721 attcatccct tccacctttg aagtggtgga agaagtaacc tatgtataca gttgtccaaa
    12781 atgtggtgct atgatccggc cggaaaaaga gtttccgttg atcaagggaa gcattgctac
    12841 accttcgctg gttgccggaa tcatgaatgc aaagtatgtc aatggcatgc cgctggcaag
    12901 acaggaacgg gaattcgcaa ggtatgactt aaatctttca acaaaaacaa tggcaaactg
    12961 gatcatcagc tgtgcagacc ggtatctggg actgctttat gggcagatga aggaagaatt
    13021 cctaaagagc agatacatcc attgcgatga aaccagaatc caggtgattg atgaaccgga
    13081 tcagaaagga tcatctcaaa actggatgtg ggtatatctg acagatcatt acagtgaagc
    13141 cccacagatg gttctctttg attatgagag aacgcgtgcc ggatatcacc cggtaaactt
    13201 ccttggagat acatttcatg gatatctgac gtgtgatgga taccaggcgt atcatggact
    13261 gaacgattcc atcaccgtaa ccggatgctt tacccatgcg agacgccgtt ttgatgctgc
    13321 actcacggca ttaaaaaagg atttcacaaa ggagcagctg aaagaaacag ttgcatatca
    13381 ggcaatgacg aggatcggaa tcctgtataa agtagaggaa ctgatcaaag ataagacacc
    13441 ggaagaacgg tatcaggaac gccagaagca gtcgcgtcca gtagtggaag ccctgtttga
    13501 atggctgcat tcgatggaag attctgtaga cagatcttcc cttattggtg atgccatttt
    13561 atatacgctg gatcaggaaa actatcttcg caggtacttg gatgatgggc atctgagcat
    13621 tgataataat agtgcggagc gtgcaatcaa aaattttgca gtaggccgcc ggaattggct
    13681 gtttgccaag agtatccgtg gtgcagatgc cagtgctgtt gtttatagta tcgcagaaac
    13741 agccctgctg aatggtctga agccgtatgt atatctttcc tatgtattag acgagcttcg
    13801 taaaatggga ccttttccaa agccggatga tctaaatcgg cttttgccat ggtcaaatga
    13861 attaccggaa ggatttcgaa ccaaaaagaa gaaataaaat gtgccgccct gatgggcggc
    13921 atgtttaaaa aggcaaggta cagatgatta cgtacttacg ttgaatcggg agagagtctt
    13981 ttaatagcat cacaattcga tattacacag agggaagatc tgtttgcaca tttttatctt
    14041 tataatgtat cacagtcttt tttgatgaga gggaacagag agatatatgc aatttacaca
    14101 agattttttc aaaccggaaa taagagaaga atttgaaatc caagctatga tgaaacgcgc
    14161 ctgggcggcg caaatggaag tattgcaggt ggttgcagat atctgtgaag aaaatggtct
    14221 gcagtatttt gcagatggag gaaccttatt gggagctgtg agacatcagg ggtttattcc
    14281 gtgggatgat gatattgata tatgcttaaa gagagaagat tataaccgct tgatcagtat
    14341 tttacaacga cagttaccgt atggctttgt gatgtcagga atgtacgctg ggacagtgcg
    14401 tcttagaatg gcagcaaatg tgtcacatct gcgtgtcata gcggatgaaa cattgtggaa
    14461 ttttaatgat tatatgaagt attttcacgg attcccttat cagcgcgtgg gaatcgatat
    14521 ttttccattg gattatattc cggtggaagc caaactggca gatatacaaa agattatgat
    14581 gatacaggga atgaatcttt tagaaaattg gacaacactg gaaaaagcag gaaaactgga
    14641 agaaagtctg caggaatatg aaaaattatg taatgttagg atagacagac agaatacgaa
    14701 aaatgggcta tggaagctga cagatgcgat tgcttcgctt tgtcataaag aagaggcaga
    14761 atatataacc aattatattt attggataga gaaagacagc tataagatga aaaaagaatg
    14821 ctatgatgag gcagttatgc tacaatttga gaatatacag attccggtcc cggcaatgta
    14881 tgatgaggtt ttaagggcag agtatggtgg ggactacatg acaccggtgc agggagcagc
    14941 ggatcatgat tacccatttt atgggcacat ggaggaggaa ctgaaaaaac agataaaagc
    15001 ggttggcttt gatggaagcg tggaagaatt ctgtcaggaa gtttcaagcg gcagactatg
    15061 ggtttgagat gagaagtgaa agaagagcat atggcttaca gaaaatggtg tgtggaaaag
    15121 tgtgatcaaa atgaacagaa cacacagtgt gggcaactgc attgtcagca ttgcccaacc
    15181 gtgaatagta tttaatcata aataatatgc atagcaattc ttgatataaa gatatgctca
    15241 tattttttta aaagttctga atcggtaatt ggctcaccac tgttaaaaaa tccatatact
    15301 gagtaattgc ctaatgtaaa acgtccttca tcgtcggctg gtatagggtt gtcaaaaaat
    15361 atttcaaaat tccgtgtgtg tgcaacggca caataaggat caccgggatg aagtgattcg
    15421 gtaatagcat attctcgttc agtttgacca ccaaatattt taggtaattg cccatttata
    15481 ggagcatcac tttgagaaat acctgccagt ttacacatga cagggagata atctgtagac
    15541 gagataatct cgtcagtgca acacggattt aagtcgctgc tacggaacat gaaagctaca
    15601 tgagaacgtt cttttgacaa gaaaggctta tcagatggaa ctaaatatcc ctgtccatgg
    15661 tcagcaaaaa gactgattag aatttctgtg tttttataat tgttttcaat ataagaatat
    15721 aataattcca ataacgtgtc tatataagtt accatttttt tgtaagtttc tgatttgttt
    15781 tcactgtaac tttgtttgac agaggtttta ctttgtttct cgtaagtacg atatttaagt
    15841 gcaagattat tttgcatggc aggagacaga tcaagctcat ctgctacatc atgcaaatcg
    15901 ccaatacaca tccataaata gtgatcggta tctttaaatg cctccaaatg ttcaattata
    15961 tttattattt cctgttcggc acgcgcacct aataattgat gttgataaat gtattgatca
    16021 atacctcttg tatatccaca tgaataagta gagcgccagt ctccatctag tttactggta
    16081 aaatatccct gctccttaaa atattcagac agagttggga aatcgtaagg aagctcattg
    16141 tttaaattat tgtgaaataa catatgattt aatgtgtcca aaccagtttc atatgaggct
    16201 aaacttggga aagtccactc agcagtgctg tacgcttgag agcatattat acccttggaa
    16261 aagaaacggt aagtatttgg catgcgttct tttaaatgtg aaccttgaat aatttcttga
    16321 gtgagtccgt cgacaaagag acttaaaact aattttttac gtttggaact gtgtccaagt
    16381 gcaattggtt ctccataata ggctttattg gaagaattaa tgtgaacacg attaggtatt
    16441 cgataataat taaaatgctg tggtatcctt tgcagtatcg tatatgtaat atcaccattt
    16501 tgaattttat gaatggtgtt tggagtctcg acagctattg gaagaaggta ttctttggca
    16561 ttaccattga tatatgagga caccccatat tcatgaaatt ttaaaaattc cccctggtta
    16621 tatacgagac tcatgttgtg gatttgcttg gtaacataat gggttggatt gcgatagatg
    16681 ccaatatacc ttgcttcagt atcggatacg taatacttgt taccgattac atagttattt
    16741 ggatcacggg gggcagagtc atttttcccc caaattgttt cccggcgttc aaaaaatgct
    16801 gctatatcaa gcaaaccctt taaatccttt ttttcagtat attcatcaat aagtatttta
    16861 agttgagaac tcaaaatgct tatttgagta tttgcatcag ttcggatatc attccagtct
    16921 gcgttgaaat aatcaaataa aaaagcacag atctcataat tttttaatgc aggtaaagtc
    16981 atattctgag cctgataaat acttgcttgg taataatagc attcataact ggttggaaat
    17041 ttacggagac agtctgttat aatattttga gcctgttcat attgcttaat tgtaagaaaa
    17101 taaatacatt gataaaaata aaaatctcgg tcatatggat aaatgagatg taaatcctgt
    17161 aagagtgttt ctactaaatt catattagag tgctgcaaag cagattcaat gaggtcttta
    17221 tctggttgtt tcattgtaca atagcctcct atctgttata attgtatcat aaagtaaaat
    17281 tacagaaaag gcttatttgc atataggaga cgatatgtta aagttaaaac aggataaatt
    17341 attggatgaa gaagcactta cagtaatttg tgaagcactt catgttaaca accaagatat
    17401 tacagatata gatattatga aaaagggaat gacgaatcgg tcatttacat ttcgatgtaa
    17461 aggcaaacgt tatatgatac gaatttcagg agttggtaca gaaaaactga ttgatcggtg
    17521 tcaggaaaaa gaggtatatg aagcaatccg tgatatggat atttgtgatc cggtcattta
    17581 tatagattct gaaaaaggat ataaaatatc ggagtttttg gaaaattcgc gggtatgtga
    17641 tccgatgaat ggtttggatg taaaaagaag catggaatgc ctgaaaagat ttcatgacaa
    17701 aaagttagct gtcggccata cgtttgatct ttttggtcag attgaaaagt atgagttgct
    17761 tcggggaaat tcaaaatctg tctatgcaga ctatgaaaaa acaaagaggg atgtttactg
    17821 gttaaaatca tttattgatc gcaatataga agaaaaggta ctgacacata ttgatgcagt
    17881 tccagataat ttcttgtttg taaaagatga gtacggaaaa gaacagatta agttgattga
    17941 ttgggaatat gcaggaatgc aggatccaca tgtggatatc gctatgtttg gtatttattc
    18001 attatatgac agagaacata tggaacaatt gattgatgct tattttccag agggctgttc
    18061 gaaaagaatc agaacaaaga tttattgtta tattgcagtg ggtggtcttt tgtggagtaa
    18121 ttggtgtgaa tataaagaaa aattgggaaa tagttttatg gagtatgcaa cccatcagta
    18181 tcagtatgca aaagagtatt cttatattgc actgttgaaa ttgcaggaaa tggagagaac
    18241 attacatgca taaagtagaa cgtgccataa tcctggcagc cggaatagga aaaagaatga
    18301 accccgttac attaggaacg cccaaacctt tggtaaaggt aaatggagtt agaatgattg
    18361 atacgataat aaaggcactg tatcagaatg atattacaga gatttatatt gtagtaggat
    18421 atttaaaaga gcaattttgt gagatacgga aggagtatca ggggataaca ttgattgaga
    18481 atccatatta tgcaacatgc aataacattt catcattgta tgttgcgcgg aaatatcttg
    18541 aaaatgcaat tattctagat ggagatcaga tcatatgtaa tgagagaatt ttgatatcgg
    18601 agttttgccg gtcggggtat aatagtgtat ggacatttga agagacggat gagtggcttc
    18661 agacagtgaa agatggaatt gtgacagctt gtagcagagt tgggggggga tgtggatggc
    18721 aactgtatag catttcgcgt tggacagctg aggatggaag aaaactaaaa aaacatctgg
    18781 aactcgagtt tgaacaaaag cacaacacac aaatatattg ggatgatatt gttatgttct
    18841 gtcattcaca ggagtatcag cttggtattt ttgaaatgca gccagatgat gtgatagaga
    18901 tagatagttt agaagagctg ataagcatag ataataacta tgtgaaatat agggaaaagg
    18961 gactagcatg aaaaaaaaag aacgtgaaca aattgattgg ttaattacaa tcgtgccatt
    19021 tttattaatc attagtttat tcgtattatt tatcatattg ccagagcaat ctaattatat
    19081 tcttggtcgg atacgatttt tcttaggaga tacttttgga agttattata ttatgatagg
    19141 gatagttttt ttttgtgttt ccatctatct tgcgggctca aaatatggaa atattatttt
    19201 gggaacacag ggagaaaaac ctaaaaattc ttttttttca tggggagcaa tgatgtttac
    19261 ctgcggattg gcagcagaca ttttatttta ttctttttca gaatggatga tgtatgcatc
    19321 agatccacat atcatagaac taggaaacat tcagaaatgg gctggtatat atccactgtt
    19381 tcattggagt tttattccat ggagttttta tttggtgctt gcagtggcat ttggttttat
    19441 gttacatgtt cgaaatagag aacgtcaaaa atattcagaa gcatgcagac caatattagg
    19501 aaaacaaacc gatggcattg gtggaagaat gatagatcta ttggcagtat ttgcattgat
    19561 tgctggtaca gcaacaacat ttggtattgc cacaccgctt atatcagaaa ttttaacgga
    19621 tgtttttcag atacagttag agcgtacagc cttgaacttg atcattctga ttatcacatg
    19681 tttaatttat acatattctt tacttcatgg atttcatgga atcagtttcc ttgcaaaaat
    19741 ctgcatttac atgtttttcg gaatcttatt gtatgtatta ttatttggtg gaaaaacccg
    19801 atatattatt gaaagtggga tatcttcttt gggtatcatg atgcagaatt tcataagttt
    19861 agctactgat acagacccgt taaggacatc ttattttcct cagaattgga caatttatta
    19921 ttgggcttat tggatggtat ggtgtgtagc ttccccgttt tttattggaa gaatttcaaa
    19981 gggcaggagc atacggcagg taattctggg tggatatatg tttggtgcgg ggtctactat
    20041 ggtaagcttt atcgttttag gaaattattc aatggaaatg cagatgtctg ggacggtaga
    20101 ttatgtgggt gaatataatc ggacaggaga tttatatcat ataatcgtaa gcattattaa
    20161 aacacttccg ggtgcaacaa tagtactgtt ggcagtggta tttacgatga ttgcatttta
    20221 tgcgacatca tttgattcaa ttgcattgat agcttcttgt tatagctatc gtaaattgga
    20281 tgggcagaag cagccacata aagttgtgca gctgatatgg tgtattttat tgattctgtt
    20341 tccgattgct ttgttattca caaatagttc tatgagtaac ctgcaatcgg taagcattat
    20401 tgcagcattt ccaattggta tggtaatgat tttgattgta ataagtttct ttaaagacgt
    20461 tgagaagtat aaaaaagatc ttgacaatag tcaaaagcaa acaaaataaa ttgaaaatga
    20521 aatatttgat tagctggaag aggaagaaaa ataatggtga caagatgtgt tatgaaaaat
    20581 gacaagaagg aaaagatatg ggatttattt gaccaaaaag aaaatgcaaa tgatatacaa
    20641 acaatgattt tagaatatga aaatgaattt tctgatgaca tggatatctt tctgatgaaa
    20701 atgtgccttt ttatctatga gaataaaata caggcagcaa ttgaaatcgg aaaacaggca
    20761 ttaagaaaga acccatattt attagaaatc catcttaaac tggcagaagc atataaggat
    20821 caatcaaagt atattgaagc gtataagcat tattgtatat ccaaattatt agcgtcattt
    20881 gcaggagaag agaaaatatg cagagattgc gaattattag caaaaggttc gttagaacag
    20941 ttggaagaac taatcactta tttacctgat gaacagaaga tatatttgtc tcaaaaaatg
    21001 ataccagcat ttcttggtta tgaaaaaaat caatttggat ataatgagcg gcgttttagg
    21061 acgtttgagc atattggtgg cgattattat tatgagagtg aagaagtaaa aaaatatgtt
    21121 ggaatgtatc atagacctag gcatgtaata aatgaactgg atgcagtgca ctggaaaata
    21181 gaatttcagg aagttgtaga ggcaaattac ttgaaactcc ctgatacaga gaaaaaatgg
    21241 attgttccag tagcggtgga aaaaaatact acccattggt ttgaaacaga taatgggaaa
    21301 atgccagtta ttcagcgaga cattaaaagc ttttattatt atagagtcgg aggcggcagg
    21361 gaaataatat cttcggatat atgttattgg ggaaatccaa taccgattaa aagtgataaa
    21421 aataagaaaa gattggtgtt aagtatattt gttgatggtc tggcacaggt attgctgaca
    21481 gcagataaat ttgcatacct aatgcctaat actgcaaaat ttttcaaaaa tggaatggtt
    21541 tgtaaacagg cttacagttc tggggaatgg acatatccga gtatagctgg agttatgtca
    21601 ggacttgcaa caacccaaca tatgatgttt cataatgaaa ttgattggaa acttccaaat
    21661 tcagttaaaa cactgatgga atattttcat gagtcgggat actatacatc tgctttttca
    21721 ggcgattgga gaataatccc atcatatggg tacgcaaggg gatgtgaccg atttatttat
    21781 caattgcaac acacagggtt ttcagtcgaa aaaatgattg gcggtgttat caatgaaata
    21841 gatgcattaa aagagattaa tcagtttgtg tgggtatcgt taggggattt acatgatgtt
    21901 gctgatgaaa tggaattacc aaccagcgtg cagacgcatt tgaaaataga agatcgcgta
    21961 tgcgaaaaag gaagcgagac atctgtaaaa caaaaatatg atatggctaa aaaaattcaa
    22021 tatgaacaga tgttacaata tatggatcgt tatttgggaa tgttattttc atatttggag
    22081 aatacatatg aagaaaatga acttatagtg gcattgtttt cagaccatgg acaaggattt
    22141 ttgataccgg aggatgggca gtttttagga ccggaaagaa caaatatagc atttatgttt
    22201 cgaaatggac aacttaaagg cgaaacagag gaagttatgt catctttgga ttatacggca
    22261 attttatgta agatggcggg aatagcatat tgtgaacagg gggttgaggg acgaactcca
    22321 agaatatttg gtggaagtgg aagaagatgg gcgttaacag agagtttgca tccaaaagat
    22381 tattatagag cggcactggt aagcgaaaac tatcgatttt atttttgcaa cccgattccg
    22441 gttggatatg atggaagatt tgagattgga gattattcaa tttgtcttac agataaagaa
    22501 ggaagaaatg tttatgctga agatgttgaa aaggaatgct tagatattat tatgaggcag
    22561 atagcaaatc tgtgtattta ttaaatggcg cgttgagatt tgatgtataa tgggagagag
    22621 aactatgaaa cgaaatatat tgttaaatcc gggaccggct acgacaaccg atacagtaaa
    22681 acaggcacag gtagtgccgg atatctgccc gagggaacag gaatttgttg aaattatgaa
    22741 gcagatacga aaagatctag ttaaaattgt gcatggagat gagcaggatg atacatctgt
    22801 attgttttgt ggttcgggta cgatttctat ggatgtctgt ttaaattcat tattgccgga
    22861 agagaagaaa attctgatca ttaataatgg agcatatagt tccagagcgg tagagatatg
    22921 tgaatattat ggaatgccgt tcattaatct ggagttccca atagatgaaa gaccatcatt
    22981 agagctgata gaacaggtac taaaagaaaa taacgatata gcacttgtat atacaacaca
    23041 taatgaaaca ggaacaggta tcttaaatcc ggtgcgggaa atcggagcac ttgtacatcg
    23101 gtatggagcg gtttttgtgg tagatactac atcgacatat gcgatgaggc cgattgatat
    23161 taagaaggat aatattgact tctgtatggc atctgcgcaa aaaggattaa tggcgatgac
    23221 aggtgtatca tttgtgattg gtaataaaag cataatagag aggtcaaaag attatcccaa
    23281 acgttcctat tattgcaatt tgtatttaca atatgactat ttcgaaaaac atggagaaat
    23341 gcactttacg ccgccagtac agacagttta tgcaatgcgt caggcaatag cagagtattt
    23401 tgcggaagga gagcaggaaa agtggaagcg ccataccaga gtatatgatg cattgtacag
    23461 tggccttgaa cgactgggct ttcagaatgt gataaagaag gaatggcagg cgggactggt
    23521 ggctgcagtg aaatatcctg atgatccaaa ctggagtttt tctgccatcc atgatttctg
    23581 ctatgagaga ggttttacca tttatccggg taaaattaat aatacggaga catttcgctt
    23641 atgtgcgtta ggtgctattg acgaaactga tattgaagac ttctttgaaa tatttgaaga
    23701 aggattaaag cagatgggag tttctttgcc agtgtattac cagaaatgag gaacggatat
    23761 ttaaaatatg ttgaaagaaa aagatgagat agctatttta atggctgcag gattaggtac
    23821 aagaatgcgc ccgctgacag agcagattcc taagccactt gttcctgtta tgggaacacc
    23881 tctgatagaa acggttattt gcgctttaga acggcgggga ataaaaagaa tatatgttgt
    23941 tgttggttat ttaaaagaac aattttctta tttgttagaa aaatatgata acttagagat
    24001 tgttgaaaat aaagaatatt tgaaaaaaac aatatttcgt cattgtatgc agtgagagac
    24061 attcttggaa gttcagattg ttttatttgt gaagctgatt tgtatgtgcc cgatgatact
    24121 atttttttga gacaatattc aacttcgtgt tattttggaa aaatgataga gggctattct
    24181 tcggactggg tattcgatgt gcaaaatggt aatattacaa gagtaggaaa aggcggtaca
    24241 gacacatata acatggcagg tatttcttat tggaaaaggt cagatgcgtt aatcataaaa
    24301 aaagcaattg aagcatcata taagaaacca ggacatgaga aattattttg ggatgagatt
    24361 gttgatcagg aattaaaacg tttaaaggtt caggtagagg aaatatcacc ggaaagtgta
    24421 atagaagttg atacactgga ggaattgagc cagctggatt cgaggtataa gacatgttag
    24481 taacagattt tgttgagcaa ataaaaaaaa taggaataaa aacattagcc ggggtgcctg
    24541 attctgcatt aaagtctttt tgtgattata tcaatgggac agggaaaaat gaatttgaac
    24601 attatgtgcc ggtaaatgaa ggggcagctg ttggcattgc gattgggagt tatttggcaa
    24661 ctggagtacc agcctgcgtt tatatgcaga atagtgggct gggaaatata gtaaatccaa
    24721 ttacatcgct tgctaataaa gatgtatatg gcataccaat gttattatta gtgggatggc
    24781 gcggtgagcc aggaacgaaa gatgaacctc agcataaata tatggggaaa ataacggaag
    24841 acttactgcg tgtgttggaa atcgaatata tagtgttgga aaaggaactt tctatgcagg
    24901 aaataatgcg tagttttgaa agagcagcac aagtgttaaa agaaggaaaa caattcgcat
    24961 ttgttttgaa aagagacttt ctacagaata ataacagtag tgattataaa aacaataata
    25021 gtttagtaag agaagatgca atagcggcaa taataaaaat gttggatgaa agtgatgtcg
    25081 tcatttctac aacaggaaag atttcaagag aagtatatga gcagagtgat agaataaaag
    25141 ggagtcatgc acaggatttc ctgacggtag ggggaatggg acatgcatct atgatcgcac
    25201 ttggaatggc tcacaaatta gagaaaaaaa gggtgtattg tctggatgga gatggagcag
    25261 tgcttatgca tatgggaagt atggcatata tagcaaaaca gaaaccgcaa aatttgatcc
    25321 atatttgtct gaataatgac gcacatgaat cggtaggggg aatgccgact ggttgtgtgg
    25381 gattaagcta tgcagatatt gccgggaccg ttgggtatga aagggtgtat tgcgtggata
    25441 agcagcagga tttaacaaag gtgttgagtg acataaaaaa gaaaaggaat cttacattca
    25501 ttgagataaa ggtggcaatg caatcgaggg cagatctggg gagaccaaag gaaactgcag
    25561 aagaaaataa aaataatttt atgaaatatc atggggttgg cttatgaaaa aagtatatgc
    25621 ttgtttttgc acggacgtaa tacatgaagg acacctgaat attattcggg aagcaaaaaa
    25681 tatggaaaat tgattgcagg tgtattgagt gatactgcaa tgattcgata taaccgcttt
    25741 ccgacggtat catttgaaga acgaaaaaaa atgttagaac agataccgga agtggatgag
    25801 gtggttgttc aggacgaggt aatgtatggt tcgattttag aaagaataaa accggattat
    25861 gttatacatg gagataattg gctaaatgat ccaatggaag tgatccgtga taatgtcatt
    25921 gaaaatctga aaaaatgggg aggtcagtta atagaaatcc catatacata taatgagcag
    25981 gtaaggaata ttgaagctgt tatgcgagaa aggactgcta tgccggaata tcgtagaaaa
    26041 cggttacggc aattattaca gttatgtcca atagtaaaga cactggaagt gcatagtggt
    26101 ctgaccggat tgatagcgga aaagacagtt gtggccaata acggtgagat tgatcaattt
    26161 gatgcaatgt ggttatcaag tctgtgtgat tcgacagcga aaggaaaacc tgatattgaa
    26221 ctggtagaca tgtcttccag acttcgtacg gtggatgacg tgttggaggt tacaacgaag
    26281 ccaatcatat tagatgggga tactggtggt atgattgagc attttgtata caacgtaaga
    26341 acattagaac gtgtaggggt ctcagcagtt attatcgagg ataagacggg actcaagaaa
    26401 aactctttgt ttggaacaga ggtagagcag acacaggata gtatagaaaa ctttactgca
    26461 aaaatcagag cggggaaacg tgcgcagcgt acaaaagatt ttatgattat tgcacggatt
    26521 gagagcctta ttttagaaaa gggattagag gatgcacttg tgagagcatt tgcatatgtg
    26581 gacgcagggg cagacggcat tatgattcac agtagaaaaa aaactcctga tgaaatattt
    26641 gcgttttgtg acagatttcg tgaaaaagat aaaattactc ctctggtcgt tgtgccgacc
    26701 tcttataatg agacatatga aagtgaacta caacagcatg gaattaatat tgtaatatat
    26761 gcgaatcagc ttacaagaag tgcctttcca gcgatgcagc agactgcaac agatatttta
    26821 agatatcata gagcaaagga agtggatgac agactgatgt caattaaaga tattattaca
    26881 ttggttgatg aagtttaagg taaatttctt gagagggttc atattcaaat cagattgaag
    26941 atgcatttca agctggaaga ggatatcaat attcagttga tcatcagtag aaaattgagg
    27001 acttacaatt gagataacaa atcatcatga gtaaccggga gcggctcaca gccgctcaca
    27061 ataccccccg aacttctcct ccgtcatccc ctcctcaatc atccgataca gctccagctg
    27121 cttcggaatc agagcactgt acacagactg agaataatcc ggcacctctg tgaacaccgt
    27181 tttttctaat tctttgtaga aagaatagga gggtttaaaa tcccggagtt ttgcaaaata
    27241 cagtgtctca tacagatagg tatggagaaa atatagtttg atttcatcat agtattcctg
    27301 gaaaaacggc gtattcttca taaaattcca gacggcaagt tggacatcgg catgcatttt
    27361 tagggtttct tcctgtctca tatcatttcg catggttcca gaatcatttt gtctgtaata
    27421 atagtaggca tcgtttaaga ttacgatttt atttgcaaaa tataaaagcg gatatacaaa
    27481 gagcggttct tcgtaaataa catgctctgc ataagcggta tgagcagttt ttaaaagatc
    27541 gtgacggtaa agtttattcc agcagccata ggtaattttc tctgagatca aaaattcttt
    27601 tcggtcattg acagaagaaa tttcaatcac ttccggcata atgttccgac cggagtccac
    27661 ggcacccaga cggtctgtat aataaaaata ttcaaactgg atgatatcag catccgattc
    27721 tttggctttt tcataagttt ccaacagaaa attctcagcg acaaagtcat cagcgtcaac
    27781 aaatgcaata tattcacccg ttgcatactg cagggcaaca tttcttgcac cgccctggcg
    27841 catattttcc tcaagtttta agatcataat gctttccgga taggcgcgtt caaattcctg
    27901 cagcatgttc caggtagcat cctcatctgt ggatgcatcg tctacaaaga tcagttcgat
    27961 ctggtcaatt ccgattgtct gctgtacaag tgacataaag catttcggaa gatattttgt
    28021 tgcattaaaa catgggatga tgacacttac ttttttcata gatcgaaatt ctcctggtaa
    28081 aaaggttaca tatggtataa taaacaaaaa tggtatatta ttaatttatc acaacaaaaa
    28141 ggaacgcaca atatcagtct gaaaagcagg gaggtcataa tgtctggaaa tatagcgatc
    28201 ggtatacagg atttttccac aatcatccag ggaaactatt tttatataga taaaacgcct
    28261 tttattaaag aatggtggga ttgcggggac agtgcgactt tgatcacccg tccgcgtcgt
    28321 tttggaaaga cacttacaat gagtatggtg gagcagttct tttccataga ctatgccggc
    28381 aggtcagatt tgtttgaaca tctggcaatc tggaaagaag aaaaataccg tgagctgcag
    28441 ggaacttatc ctgtcatcag tctgtcattt gcgcggatta aagagagaga ttatgagaaa
    28501 acaaaacaaa agatgtgtga ggtgttaaga aacatatata taaagttttg ttatattaaa
    28561 gacagtgaaa agcttacaga tgccgacaga gcatattatg agcgtatgtt ggaggaaaat
    28621 ataaaagaga cggatgcgac atcttcttta tatcagttat cagattttct gtatagatat
    28681 tatggaaaaa aagttatcat tttgttagac gaatatgata cacccatgca ggaagcattt
    28741 gtggatggtt actgggatga acttgtcgca ttcacccgaa gcctgtttaa ttcgacattt
    28801 aaaacgaatc cggcactgga acgtggaatt atgacgggaa tcacaagagt aagtaaggag
    28861 tccgtttttt cagatttgaa taacttaaag atagttacga ctacatcaaa tgaatatgct
    28921 tctgtatttg gttttacaga gaaggaagtc tttgatgcat tggaacagta tggtcttgag
    28981 aaagaaaaaa aggaagtaaa aagatggtac gatggtttca tttttgggga gcacaaagat
    29041 atttataatc catggtcaat tttaaattat ctcgatacac agttatacaa aacattttgg
    29101 gcaaatacaa gtgcgaatag tctggtagga aaattgattc aggaaggaaa ccgtacaatt
    29161 aaggaaaaat ttgaaaaatt attatgcgga gaatgcatct ggtcagaaat tgatgagcag
    29221 attgtataca atcaactaaa tggaaatgaa aaagcggttt ggagtctttt gctggcgagt
    29281 ggatatttga aagtattatc ttatgaaacg tatcaggata ttgaggaggg gaagatgccg
    29341 aaataccagc ttgcgttgac gaatctggaa gtaaagttaa tgtttcaggg tatggtacat
    29401 gactggttcg ctcctgtaca accagattac aatgattttg taaaggcgat gttacttgat
    29461 gatgtggatg cgatgaatga atacatgaat cgaattgcta tacagacatt tagttatttc
    29521 gacaccggag aaagggcatc cggggcagag cctgagcgtt tttatcatgg ctttgtatta
    29581 ggtctgcttg ttgacctgcg ggatagatat caccttaaat ccaaccgcga aagtgggttt
    29641 ggcagatatg atgtaatgtt agaacccaaa aattcaaagg aatgcaatgc agttatttta
    29701 gaatttaaag ttcgaaatcc acgaaaggaa aaaagtcttc aagagacagt tctgtctgcc
    29761 ttaaagcaga tttgtgaaaa aaaatacgat gcagacctgc ttgataaagg aatcagacag
    29821 gaacagatat atcattatgg atttgcattt gaaggcaaaa aagttttgat tgggacagac
    29881 agggaggagt gaatatgccc accaatatag cgatcggcac acaggagaac aaccacatgt
    29941 tatcagtctg catcatcacc aaaaacgaag aacacaatat agcgcgctgc ctcaaatcat
    30001 tccagaaaac cggatttgag ctgatcgtag cggacaccgg atcgacagat cagacaaaaa
    30061 aaatcgccgc agaatatacg gaaaatatct atgatttccc atggtgcgat gatttttcgg
    30121 cagcaaagaa ttttgcggtt tcaaaagcag cacatccgta tgtgatggtc attgacagcg
    30181 atgaatattt acagcagatt gatcgggtac agttagagaa aatgattgcc gaacatccag
    30241 gtgaggttgg caggatccgg agaatcaata ttatttccgg aaaagatgga aagcaggaaa
    30301 ataaagagtg gatcaaccgc atttttgcaa aagaaagttt tcattacacg ggaagaatcc
    30361 atgagcaggt aactgcctgt gacgaaaagg aatatcgtac atacgaagca ccggtcgtca
    30421 tcggccatac gggttatgat cttccgaaga aagaaaaaaa ggcaaaagcg ctgcgcaaca
    30481 taagactgtt agagcaggaa ttaaagaatt caggatggga tgccgaagca catgccacgc
    30541 agttagatca gaatatcgca aagcaggata cggatgcaga gcagaaatct aaaattacgg
    30601 atgcaaaaaa agagcagcag atcccgtatc tattgtatca gcttggaaaa agctattaca
    30661 tggcagaaga ttataacgag gcatgcttct ggttcgccca tgggctcagt tatgaccttg
    30721 aaccaaagtt agaatatgtc atcgatatgg tggaaaccta cggctatgcc ttgatcaaca
    30781 gcggacgcgc cggggaagca cttttctttg aaaatattta tgaagaattt ggaaatagtg
    30841 cggattttca gttcctgatg ggactcattt atatgaacaa cgctatgttt gatgcagcag
    30901 ttggagaatt tttgaaagcg gtcaaacacc gggactgcag gatggcggga gtaaattcct
    30961 atgcagctta ttataatgtt ggagttattt atgaatgtct ggagaaaatc agtgaggcaa
    31021 agtattatta tcagaagtgc ggtggttatg agccggcaaa aaaacgttta agattgataa
    31081 acagttaaat ttattatagt cagcttattg gagaaacaga gtgaaaaata taatttttca
    31141 aatgcagaat ggagattaga atgggaatat atttaaatcc gggaaatgaa gaatttcaga
    31201 aagcacttaa ttccaagata tatgtggata aaaccatgct gatttctgaa atgaatcaga
    31261 atctgaatac cgaacatcag aatatatgcg taagcagacc tcgccgtttt ggaaaatcta
    31321 tgactgcaaa tatgcttgta gcttattata gcaagggatg tgattcgaaa agcatgtttg
    31381 cggattataa gattgcacag gatgaaagtt ttgaggcaaa tctgaataaa tataatgtcc
    31441 ttcatgtcaa catgcttgac tttcttaacc gggcgcagtc ggtggatgca atgatcgatt
    31501 atatgcaaaa gagactttta tgggatatca ggcgggaata cggagatgta gactgttttg
    31561 accgggaaga tcttattgat gtattagaga acatctatag tcagaaaaaa cagaaattta
    31621 tcatcattat cgacgagtgg gattgcatat ttcgaaagta tccgggggat gatgaagcac
    31681 agaaaaaata tctggatttc ttgtgcctgt ggatgaaaga taagccatat attgcgttgg
    31741 cttatatgac gggaatactg ccgattaaaa agtatggcga gcattcagct ctcaatatgt
    31801 ttgatgaata ttccatgacc aatcaaaggg aactcgctga atttaccggg tttacggaag
    31861 aggaagttca aagtctgtgt gtgtcatatg gtatgcct
//
