LOCUS       c00004_gnlPro..        23228 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EILEMEPP_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 19:00:08
            Original ID  :: gnl|Prokka|EILEMEPP_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 61576
            Orig. end    :: 84804
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23228
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[71576:74804]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13228
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23228
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23228
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             774..1523
                     /locus_tag="ctg4_56"
                     /transl_table=11
                     /translation="MAKIEPIRLQKFIAQCGIASRRKAEELILGGHVKVNGKTAILGDK
                     VLPTDKVFVRGKRIVVPKGGNYRYIMLNKPRGFITTMNDERGRKCVAQLVENVGERVYP
                     IGRLDKDSEGMLVFTNDGDFANKVMHPKNNVYKIYRVTVRPSIDEDQLVKLETGVELDG
                     KKTAPAYVRVIHKEQGRVVLEMILHEGKNREIRRMCEAVGLEVARLKRTQIGGVKMGML
                     KQGDWRDLTEQEVKKLLANPFLNGKQL"
     CDS             1754..3067
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CT_Btheta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_57"
                     /sec_met_domain="CT_Btheta (E-value: 1.2e-67, bitscore:
                     222.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIEKINQAKAEIAATSAYKTITAFFDADSFCEIDAFAKSGEGFA
                     EVVAGFGTVEGMPVYAFAQNSDICGGAMSKAQAAKLKKLYDLALKTGAPVVGFYDSVGG
                     RLNQGTELLAGCGDVLNAAASLSGVVPQISVVLGTCLGTNALNAASADIVIMSKDAQLS
                     LSVTGKHSDAAYNAENGIASIVCDDADKAIKAAKELILYLPSNNLTMAPQSFEEAPAED
                     GCGCVVSRTVDGNSIVKLFNDYGKEANVRFARLGGQVVGIVVTKGKELGCKSANKVAKF
                     VRFCDAFSLPVVTFVNCPGFESIKSATKASAAYAEATTVKISVVTGKAIGSGYVALAGT
                     GANADVVYALPDAVISPVNVEAAAFIMAPEVMNVATDKQAEVAQKFADENLSAYNAAQN
                     GYVDGIVEEAQLRQTLISALDMLSGKRVSTLSKKHSTI"
     CDS             3106..3471
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.7; E-value:
                     8.2e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_58"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.3e-20, bitscore:
                     65.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLRITVNGTAYDVQVEELGGSSAPAAAAPAPAAAPAPAAKPAA
                     TAGAQGSVVVKAPMPGTVVNVVVSAGQAVKAGDDLVFIEAMKMETPVKAPQDGTVATVD
                     VAKGESVDSGKVLVTLN"
     CDS             3502..4905
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PYC_OADA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_59"
                     /sec_met_domain="HMGL-like (E-value: 7.5e-49, bitscore:
                     160.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 9.2e-55, bitscore:
                     178.9, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKIRVTETALRDAHQSLIATRMTTEEMLPVLDKLDKIGYYSLE
                     CWGGATYDSCLRFLNEDPWDRLRTIREHCPNTKLQMLFRGQNMLGYRHYADDCVEYLVQ
                     RSIANGIDIIRIFDALNDIKNLKTAIKAANKEGGHAQVAISYTTGPVFTDEYYVEYAKR
                     IADAGADSICIKDMAALLTPTRTESLVKAIKAAVPELPLQLHTHYTSGLASMCLLKGVE
                     AGADGIDTAISPLALGTSHAPTESMVAALSGTEFDTGLDLKQFTDIRAYFMTLREKYIK
                     SGLLDPKMLATDANALIYQVPGGMLSNLLSQLKQAGKEDKLDEVLAEVPRVRKDSGYPP
                     LVTPTSQIVGTQAVFNVITGKRYSMCTNEFKGLVAGEYGTTPMPIDPEFQKKIIGDKKI
                     IKGRPADQLEPELDKLRGEIEQWIEQPEDVLSYAQFPKVALDFFEKRRNAKVGINGDKL
                     DKKNMVHPV"
     CDS             5100..6122
                     /locus_tag="ctg4_60"
                     /transl_table=11
                     /translation="MKKFLTTLIAFAMCFSVVTTAFAATPDETSDSDLISDIKQAMLDT
                     YYGDEKPDFIEVRIYGTASDGGVYFDFIDSFTHWADEVEFDLGNYTISYPSDCPVMLYK
                     NNKVYTLSDAYETGAIDDDMLYELYTWGNLWGKMDIIQKGENSSLIFKIKREFIDTYHD
                     GKAPEYLNIEIVGSTSDGGVYFMHNEGFSLDYSIEETIGDYTYYYNHNDDVMLYKNGNV
                     YSIKEAYESGVIDDSILEELSKINFGLESNKPNTTVPTEPTTSVATVDEPVTVPDTTSA
                     TSATKPVSTSDTATNDTPSNSQNNSGAVQTGQNSVAVILLVAMLAGCAVIFAKRRNYFK
                     "
     CDS             6319..7965
                     /locus_tag="ctg4_61"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKISKAESVYGGVKLTWNKVKGVAKYRVYYKGSKGWTKLADTTSTSYTDKKVSSGKS
                     YTYTIRCISKDGKKFTSGYDSKGKTVKYVATPKISKIETVYDGTKITWNKVTGAEKYRV
                     YYKDRTGWNKLVDTTGTSVVDEGLYPAEYNVSQGVANTIYTVRCISKDGKSYKSGYDSK
                     GKALTGYKQSVPDVMNISTVSGGIKLEFNYALPENSKYRVYKKENGSWKKLAETYNQYY
                     TDKNVKAGKSYTYTVRGVSKDGKKFTTSYNPSGVTLKYKTTNKTRDDFVNYLMNHQSEW
                     LPHDYMGMRAQAGFEFVDLDFDGIPELIVQESGGTMCNVDAAIYSFKNGKLVKSKYNRN
                     DAVQNRFNFYYNKGTKKYEILGTAISAAGTANDHTYEKFQLKYDGYSVTTDYFAAYYVT
                     YPMNTPNGNYSYTYYNGADSYYFGIGNHKKISKSNYNDILRSRFANRVNAHKRSQFIYR
                     TAADTNWNNMSYSQKKQALLDSYDSFSYDKY"
     CDS             7984..9822
                     /locus_tag="ctg4_62"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKISKAESVYGGVKLTWGKVSGAAKYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRN
                     YTYTVRCISADGKSFTSGYDSKGKSVKYIAAPEISKLENVNGGVKISWGKVSGATKYRV
                     YYKGSKGWTKMVDTTSTSYTDKDVSSGRNYTYTVRCITSDAKKFTSGYNPTGKSVKYVA
                     TPKISKLEVTYDGVKLTWNKVAGAEKYRVYYKDRNGWTKLGDTTGTTMLDMNVVSKEFD
                     LSVDDIYYTVRCISKDAKSFTSGYDSKGTPIGDHQDCPEIYSIGAVNNGVEMHWTGDAP
                     KFRVYIKENGSWKKIAETYDNYYVHKGAKSGSNTYTVRGVSKDGKKFTTMFNPTGVTYR
                     YKTSDKTRDAYINYMMNHTDEWMPSLGSNHNLSGVMFLDFDFDGVPELVAQKADSKEYG
                     FHSVVYKFEDGKLKRVGNVNDGFSIYYNKTAKKYEVHDLDIYLNVDDGYYWTGNSIITY
                     DGENLFANMYSARGVGEESNNNIYYKYFDGNDKNISRAKYNEINLKQFNNCVNAHMFTE
                     FIATGYGDTSVWGEKTTAENKQSLLDAYNSFSYEKY"
     CDS             complement(10001..11041)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_63"
                     /sec_met_domain="IlvN (E-value: 5.3e-83, bitscore: 270.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 8.3e-60, bitscore: 194.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLR
                     DSGCDVIIGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKLAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(11102..11593)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_64"
                     /sec_met_domain="ALS_ss_C (E-value: 5.8e-29, bitscore:
                     93.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRVNTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             complement(11606..13228)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_65"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.8e-42, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             complement(13529..15853)
                     /locus_tag="ctg4_66"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCAHCAGKIEAKIAETDGFEDVNFNFATKLLNFKS
                     EKQNPVSEIQAICDSIEDGVTVVDKTPKTDLKKYTYTLDNLNCAHCAGKIEAKIAETDG
                     FEDVNFNFATKLLNFKSEKQNPVSEIQAICDSIEDGVTVVDKTPKNDITTKADPEITKK
                     KINHDTIFLAISIVLAVVSEILHLTLDGVTAVHYVVLAACFVATILSGYKVFIKGAKNI
                     LKLRIDETTLMAVAVIAAFCLGDFVEAAMVTILFSIGEIFEDRAVDASRRDIEKLANIR
                     PDTATIIVDSAEQIVPAESVEIGSIIEVKPYERVPLDGIIIKGKTTLDTSALTGESLPV
                     DAGEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDAAAQKGNSEKLISRFASV
                     YTPVVVLIAVAIAVIPPLCGLGAFSEWLYRALVCLVASCPCAIVISVPLSYYSGIGAAS
                     EVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLRVNKVNTVGSYSADEVLALAAASEK
                     YSAHPIASAIREKANGLKLPELSDYSESAGHGTSAVYNGKTIQCGGSKILSDEQKKIAN
                     KDDSVFVIYDGQLIGSLNVSDTVRPEAKEVISQLKALGVKNTVMLTGDRQQPAENVKNE
                     LGLSECHAELLPAQKLELFKGLKSKSKGACFVGDGINDAPVLSASDCGIAMGFGSEAAI
                     EASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKALVIILAAFGLAQIWMSVI
                     ADTGVSVVCVLIAARLLKKKY"
     CDS             complement(15865..16185)
                     /locus_tag="ctg4_67"
                     /transl_table=11
                     /translation="MENEKEKVTTPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENE
                     MSVLNIAEALNMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHV
                     LE"
     CDS             16820..18112
                     /locus_tag="ctg4_68"
                     /transl_table=11
                     /translation="LEKFVVTGGKPLSGEVTISGAKNAAVAIIPAVILCDEPCQIENIP
                     NISDVSLISRILQQMGANVRRINRSSLYIDPTKIRTCNAVTDLVRGMRASYYLLGALLG
                     KYGKAKVALPGGCNFGVRPIDQHLKGFEALGATTQLVDGAIIEAECENLVGTHVYLDVV
                     SVGATMNIMLAASKAKGQTIIENAAREPHIVDLANFLNSMGADVRGAGTDVIKIRGVEY
                     LHGITYSIIPDQIEAGTYMCAAAATRGCITVKNITPKHLESISAKLREMGVKITEYDEA
                     LKVDASSAPLKRCNIKTMPHPGFPTDCQPQFAALLMSVPGTSIINENVWDNRYQYVSEL
                     VRMGAQISVEGRLAIIEGGTPLTAAPVKATDLRAGAAMIIAALEINGTTEISNIQFIER
                     GYEDVVEKFRALGADIKKVYFTGDNEQELGA"
     CDS             18239..19027
                     /locus_tag="ctg4_69"
                     /transl_table=11
                     /translation="LARAVPLFSGSKGNSYYIGSATEGVLIDAGRSCKQIENAMLANGI
                     DMSSIGAVFITHEHTDHCSALRVLAKRYGFKVYSSLGTLNALRAGNKLDPNTDADVITD
                     EVVIGNMRVQRFDTPHDTAESCCYRVTAPDGKSALIATDMGVMLSDVRTAAEQSDFVVL
                     ESNHDINMLKNGFYPYPLKQRILSNRGHLSNEACAKELVNLVEKGTLRLMLGHLSEENN
                     TVPLAMSTSVDLLTSNGMKYKSDYSLDVAPSISTTKTIIF"
     CDS             19049..19534
                     /locus_tag="ctg4_70"
                     /transl_table=11
                     /translation="MIKINIICIGKIKEKYFTDAIAEYAKRLTAFCKFNIVELSEERIK
                     SNTPNQSQIDEVISSEGKRIMQKISPSDYVVAMCIEGKLMSSEELSKLIDNASVSGKST
                     VDFIIGGSYGLDESVKKRADVRLSMSKMTFPHQMARMILSEQIYRAFEISSNGKYHK"
     CDS             19549..21297
                     /locus_tag="ctg4_71"
                     /transl_table=11
                     /translation="MALDGIFLRHIKNEIEKEALGARVSQIYQPNREELVFGLRTFSGN
                     KKLLLSARANSPRVNFCSSTPENPAQPPMFCMLLRKRIGGGKLVGLRQNGCDRVLMLDF
                     ECVNELGDTVMITVVCEIMGMYSNIIIVDSNGVIIDSLKRVDLTMSSKRLVLPNIKYEL
                     PESQNKLNLLECTALDVCTTVKNLDTEMPLNKALLRTIEGVSPIVCREIEYKVMEGATN
                     RIEGVLFDRLAVEIEKLKCVCSDCSGKPVVVYREDGKPMDFCFMNVEQYGDFARVEDRE
                     SFSDLLDGFYEARDSRDRMRVKSQSLTKLLNNTLERFARKIVKQQSELERCADREHLRI
                     CGDLLQANIYRIERGAEYVDVENFYDENNAILRIKLNPAISPSANAQKYYKDYRKAKNA
                     EIMLKEQLEKGREELDYIDSVLDTVDRAENEKDLSQIREELTEQGYLKVQKGKKPRQTT
                     LPPLEFESSDGFKILVGRNNRQNDKLTLKTASKNDMWLHTKDIHGSHVIVVSDGKEISD
                     TAIFEAAQLAAYHSKARNSSQVPVDYTLVRYVSKPNGSKPGMVIYVNNKTLYVKPSQTI
                     EKQKIQ"
ORIGIN
        1 gttttcacaa cgaatgaatg aaaaggcaaa gcaaatcggt atgacgaata ccaattttgt
       61 aacgccgagc ggacttgacg acgaaaacca ttactcaagt gcaaaagata tggctctgct
      121 tatgtcatat gcacttgaaa ataacgattt tgcaaatctt acggctaaga agagcgtgac
      181 cgttgaattt cttgaaccga aatcaaagaa aaccgcatat gcaaatcata acaggctttt
      241 gtcgctttat ccctactgta caggcggaaa aacaggctat acaacggcgg cagggcggtg
      301 ccttgtttcc tctgcaaaaa aagacggtgt aacgcttgtg tgcgtcactc tgaatgaccg
      361 caatgattgg aatgaccata tttctcttta tgattacgct tttgaaaagt acaggggagt
      421 tgactgcaag gacgctgact tttgtgccga tattccgtgc gtgggcggtg ataaggacag
      481 cgtgacggtt acaggcgaga agaacagcac aatcgtttta aagtgtgagg actgcgataa
      541 aatcaagaaa aaaatcttta tagacagctt tttgtatgct ccgattgaaa agaacgaatc
      601 ggtcggcaga attgaataca cactcggcgg aaagctgctt tataaatgca acattgttgc
      661 aggcgaaaag attaaatcgg ataaaaagag tgtgtcaata ttttcagcaa taggaaatct
      721 gttttcgtaa cagcttaaat atacagaaaa ttttaataaa aaggaattta catatggcta
      781 aaattgaacc tataagactt cagaaattca tagcgcaatg cggtattgcg tcaaggcgaa
      841 aagccgagga gcttattctc ggcggtcatg tcaaggtgaa cggcaaaacc gcaattctcg
      901 gtgacaaggt tcttcctaca gacaaggtgt ttgtaagagg caagaggatt gttgtgccga
      961 agggcggtaa ttaccgatat attatgctca acaagccccg cggattcatt accacaatga
     1021 atgatgagcg tggcagaaag tgcgttgcac agcttgttga gaatgtcggt gagcgagttt
     1081 atccgattgg cagacttgac aaagacagcg agggtatgct cgtttttaca aatgacggtg
     1141 attttgcaaa caaggttatg cacccgaaaa acaatgttta caagatttac agagtaaccg
     1201 ttcgaccgtc aattgacgaa gatcagcttg ttaagcttga aacaggtgtt gaacttgacg
     1261 gcaagaaaac cgctcccgca tatgttcgtg taattcacaa ggagcagggc agagtagttc
     1321 ttgaaatgat tcttcacgag ggcaagaacc gtgaaatcag aagaatgtgc gaggctgtcg
     1381 ggcttgaagt tgcaagactc aaacgcaccc agatcggcgg tgtaaaaatg ggtatgctca
     1441 aacagggcga ctggagagat ttgaccgaac aagaggtcaa aaaactgctt gcaaacccgt
     1501 ttttaaacgg caaacagctt taattttccg tttttgaaaa atacttccga aacggtcaat
     1561 aaaactattc gttaatttga caataaattt acggttttta cggaataact attaaatgtg
     1621 ttaaaaattg aaatagtgca tcgtgttttt cttgtacttt tgaagattat agagtataat
     1681 gtattgtgta gaaaattagt atgcacgctc agttttcgtg catattcaat acatggtatt
     1741 ggaggatttt aagatgagta ttgaaaaaat caatcaggca aaggctgaaa ttgctgcaac
     1801 atctgcttat aagacaatta cagcattttt tgacgcagac agcttttgtg aaattgatgc
     1861 ctttgcaaaa tccggtgaag gctttgccga ggttgttgca ggctttggaa cagtagaagg
     1921 tatgcctgtt tatgcgtttg cacagaacag cgacatttgc ggcggtgcca tgagtaaggc
     1981 acaggctgct aagcttaaaa agctttatga cctcgcactc aagacaggcg ctcctgttgt
     2041 aggtttctat gacagcgtag gcggcagact taatcaggga acagaacttc tcgcaggctg
     2101 cggtgatgtt cttaacgcag ctgcttcact ttcaggtgtt gtacctcaga tttcagttgt
     2161 tctcggcact tgcctcggaa caaacgctct taacgctgca agcgcagaca tcgttattat
     2221 gagcaaagac gcacagcttt cactttcggt aacaggcaag cattccgatg ccgcttacaa
     2281 tgctgaaaac ggtattgcct caatcgtttg tgacgatgca gacaaggcaa tcaaggctgc
     2341 aaaggaactt atcctttatc ttccgtcaaa taacctcacg atggctcctc agtcatttga
     2401 agaagctccc gcagaggacg gctgcggttg tgttgtcagc agaactgttg acggcaacag
     2461 cattgtaaaa ctcttcaatg actacggcaa ggaagcaaat gttcgttttg caagacttgg
     2521 cggacaggtt gtaggtattg ttgttacaaa gggcaaggag cttggttgca agtctgcaaa
     2581 caaggtagca aagtttgttc gtttctgcga cgctttctca ctccctgttg taacattcgt
     2641 aaactgcccg ggctttgagt caatcaagtc ggcaacaaag gcgtcagccg cttatgccga
     2701 ggcaacaaca gttaagattt ctgttgttac aggcaaggca atcggttcag gctatgttgc
     2761 tcttgcaggt acaggcgcta atgcagatgt tgtttacgca cttcccgatg cggttatttc
     2821 acctgttaat gttgaggctg ctgcattcat tatggctccc gaagttatga atgttgccac
     2881 agataagcag gctgaggttg ctcagaagtt tgctgacgag aatctttctg cttacaatgc
     2941 cgctcagaac ggctatgttg atggtattgt tgaagaagct cagctccgtc agactcttat
     3001 ttctgctctt gatatgctct cgggcaagcg tgtttcaaca ctttcaaaga agcattcaac
     3061 tatctgataa atgattactt gttaaaataa aaggggatac taaaaatgaa gaatttaaga
     3121 attacagtta acggcacagc atatgatgtt caggttgaag agctcggtgg ttcttcagct
     3181 cccgcagcag cagctcctgc tccggcagcc gctcccgctc ctgcagcaaa gccggcagct
     3241 accgcaggcg ctcagggttc tgttgttgta aaggctccta tgcccggtac agttgttaat
     3301 gttgttgttt cggcaggaca ggctgttaag gctggagatg acctcgtatt catcgaggct
     3361 atgaagatgg aaactcccgt taaggctccg caggacggca cagttgcaac agttgatgtt
     3421 gcaaagggtg agtcagttga ctcaggtaag gttctcgtaa cacttaacta atcaataatt
     3481 cggagaaagg gatgctgtaa aatggcaaaa aaaatcagag ttaccgaaac tgctctgcgt
     3541 gacgctcatc agtcactcat tgcaacaaga atgacaacag aggaaatgct ccctgttctt
     3601 gacaaactcg ataaaatcgg ttattactca ctcgaatgct ggggcggtgc aacatatgac
     3661 tcatgcctca gatttttaaa cgaagatccg tgggacagac tccgcacaat cagagagcat
     3721 tgccccaaca caaagctcca gatgcttttc agaggacaga atatgctcgg ttatcgtcac
     3781 tatgccgatg actgcgttga gtaccttgtt cagcgttcaa tcgcaaacgg tattgacatt
     3841 atccgtattt ttgatgctct taacgacatc aagaatctta aaacagctat caaggccgct
     3901 aacaaagaag gcggtcatgc gcaggttgct atcagctaca caacaggtcc tgtattcaca
     3961 gatgaatact atgttgagta tgctaagaga attgcagacg caggtgcaga ttcaatctgt
     4021 atcaaggata tggctgctct tcttactccg acaagaaccg aaagccttgt aaaggctatc
     4081 aaagccgctg ttccggagct tccgcttcag ctccacaccc actacacatc aggtcttgca
     4141 tcaatgtgtc ttttaaaggg tgttgaggca ggtgccgacg gcattgacac agcaatcagc
     4201 ccactcgctc tcggtacatc acacgctccg acagagtcaa tggttgccgc tctttcaggc
     4261 acagagttcg acacaggtct tgaccttaag cagttcactg acatccgtgc ttacttcatg
     4321 actctccgtg agaagtacat caagtcagga cttcttgatc ctaagatgct cgcaacagac
     4381 gctaacgctc ttatctatca ggttcccggc ggtatgcttt ccaaccttct ttcacagctt
     4441 aagcaggcag gcaaagagga caagctcgac gaagttcttg cagaagtacc ccgtgttcgt
     4501 aaggattcag gttatcctcc gcttgttact ccgacatcac agattgtcgg cacacaggct
     4561 gtattcaatg taatcacagg caagcgctac tcaatgtgta caaacgagtt caagggactt
     4621 gttgccggag agtacggtac aactccaatg ccgattgatc ctgaatttca gaagaagatt
     4681 atcggtgaca agaagattat caaaggtcgt cctgcagatc agcttgagcc tgagcttgat
     4741 aagcttcgtg gcgagattga gcagtggatt gaacagcctg aggatgttct ttcttatgca
     4801 cagttcccga aggttgccct cgacttcttt gaaaagagaa gaaatgccaa ggttggcatc
     4861 aacggcgaca agcttgacaa gaaaaatatg gttcacccag tttgatttga caactaaaat
     4921 taacatttat gccactttcg ctatgaaagt ggcattttta tttgaacaga attattcttg
     4981 ctaaattttt agcaactata ttgcattaca tatattttag cggtataatt aagtaaattg
     5041 aatatctgtt gcatatacca ttattataga tagaataaat aaaaggtgag gaaataaaaa
     5101 tgaaaaaatt tttaacaaca ttgatagcat ttgctatgtg tttttcggtg gttacaactg
     5161 cttttgcggc tacacctgat gaaacttctg attcagactt gatttcagat attaaacagg
     5221 ctatgttaga tacatattat ggtgatgaaa agcctgattt tattgaagta agaatatatg
     5281 gtacagccag tgacggtggt gtgtattttg attttattga cagttttaca cactgggcag
     5341 atgaagtgga atttgattta ggaaattata ctatttctta tccgagcgat tgtcctgtta
     5401 tgttatataa aaataataaa gtatatacat tgtctgatgc ctatgaaaca ggtgcaattg
     5461 atgatgatat gctctatgaa ttatacactt ggggaaatct ttggggaaag atggatatca
     5521 tccaaaaagg cgaaaattca tctctcattt ttaaaattaa aagagaattt atagatacat
     5581 accatgacgg caaagcacct gagtatctca acattgaaat tgttggttca acaagtgacg
     5641 gcggagtata ttttatgcac aatgaaggct ttagccttga ttattcaatt gaagaaacaa
     5701 ttggtgacta tacttattat tacaaccata acgatgatgt tatgctttat aagaatggca
     5761 atgtttactc aattaaagag gcttacgaaa gcggagttat tgatgatagt attcttgaag
     5821 aattgtcaaa aataaatttt ggtttggaat ctaataaacc gaatacaact gtacctactg
     5881 agcctacaac ttcggttgca acagttgacg aacctgtaac agtacctgat acaacttctg
     5941 caacttctgc aacaaagcct gtttcaacaa gcgacacagc aacaaatgac acaccgagca
     6001 attcacagaa taacagcggt gctgtacaga caggacagaa cagcgttgct gtaattcttc
     6061 ttgttgcaat gcttgctggc tgtgcagtaa tttttgcaaa acgcagaaat tattttaaat
     6121 aattcaaaac atcaacagaa tatataaaat aaaccgttct cgcttttgtg aacggtttat
     6181 ttattttagc ttaaaaattt gtgatagttt atcaagatgt attgcttttt atatcattta
     6241 atgttacaat taacttgcat aaaaatatag cgaaagtttt taataatgcg tagaatattt
     6301 acaaagcggg ggatagatat gaaaaagttt ttacctatag caatggcggc ggttatgtcg
     6361 atgtctgcgg ttgcggtttc agctgtttct gcaaatgcgg ttgaaccgct gaacacaccc
     6421 gtgcagtatg cacaggttgc aagggcaagc ttggcaactc cgaaaatttc aaaggctgaa
     6481 agcgtttacg gcggtgtaaa gcttacatgg aacaaagtta agggcgtggc taaatacaga
     6541 gtttactaca agggcagtaa aggctggact aaacttgccg acacaacctc aacttcatat
     6601 accgacaaaa aggtttcatc aggcaaaagc tatacataca caatcagatg tatcagcaag
     6661 gacggcaaaa aattcacaag cggttatgat tcaaagggca aaacagtaaa atatgttgcc
     6721 actccaaaaa tttctaagat tgaaactgta tatgacggca ccaaaattac atggaataaa
     6781 gttacaggtg cagagaagta tcgtgtgtat tataaagaca gaacaggttg gaataaactt
     6841 gttgacacaa caggtacaag tgttgttgat gagggattat atcctgcaga atataatgtt
     6901 tctcaagggg ttgctaatac gatatatact gtccgttgta taagtaaaga cggcaagagt
     6961 tataaaagtg gatatgattc caaagggaaa gcattaacag gatataagca atcagttccg
     7021 gatgtaatga atatatcaac cgttagtggc ggtataaaac ttgagtttaa ttatgcttta
     7081 cctgaaaact caaaataccg tgtgtataaa aaagaaaacg gctcttggaa gaaacttgct
     7141 gaaacttaca atcaatacta tacagataaa aatgttaaag ccggcaaaag ctatacttat
     7201 acagtaagag gtgtatctaa ggacggtaaa aagttcacaa cttcctataa cccgtcaggt
     7261 gtgacattaa agtataagac aactaataaa acaagagatg attttgttaa ttatcttatg
     7321 aatcatcaga gtgaatggtt acctcatgat tatatgggta tgagagcaca ggctggattt
     7381 gaatttgttg atcttgactt tgatggcatt cctgaactca ttgtacagga atccggtgga
     7441 acgatgtgca atgtagatgc agcaatttat tcgtttaaga acggtaaact tgtaaagtcg
     7501 aaatataata gaaatgatgc agtacaaaac agatttaatt tttattataa taaaggcact
     7561 aaaaaatatg agatacttgg cactgctatt tcagcagcag gaacagccaa tgatcataca
     7621 tacgaaaaat ttcagctcaa atatgacggt tattctgtaa ctacagatta ttttgctgca
     7681 tactatgtga cttatccaat gaatactcca aatggaaatt attcatatac atattataac
     7741 ggtgctgata gttattattt tggtatagga aatcataaga aaatttcaaa atcaaattac
     7801 aatgatatat taagaagcag atttgcaaat cgtgtaaatg cacataaacg cagtcaattt
     7861 atttatcgta cagctgccga cacaaactgg aacaatatgt catattctca gaaaaaacag
     7921 gcattgcttg attcatacga ttcattctcg tatgataaat actaattaaa gcgagggata
     7981 gatatgaaaa agtttttacc tatagctatg gcggcggtta tgtcgatgtc tgcggttgcg
     8041 gtttcggcag tttctgcaaa tgcggttgaa ccgcttaaca cacctgtgca gtatgcacag
     8101 gttgcaaggg caagcttggc tactccgaaa atttcaaaag ccgaaagcgt ttacggcggt
     8161 gtaaaactga cttggggcaa ggtaagcggt gcggctaaat acagagttta ctacaagggc
     8221 cgtaaaggtt ggacacgaat ggttgataca acttcaacct catatatcga caaggatgtt
     8281 tcatcgggca ggaattacac ctatactgta agatgtattt ctgctgacgg aaagagcttt
     8341 acaagcggtt atgattcaaa gggcaaaagt gtaaaatata ttgccgcccc cgaaatttca
     8401 aagcttgaaa atgtaaacgg cggtgtgaaa atctcttggg gcaaagtaag cggtgcgact
     8461 aaatacagag tttactacaa gggcagtaag ggctggacaa aaatggttga tacaacttca
     8521 acctcatata ccgacaagga tgtttcatcg ggcagaaatt acacttatac tgtaagatgt
     8581 attacatcag acgcaaagaa atttacaagc ggttataacc cgacaggcaa gtcggtaaag
     8641 tatgtagcca caccgaaaat ttcaaaactt gaggttacat atgacggtgt aaagctgaca
     8701 tggaacaagg tcgcaggtgc agaaaaatac cgtgtgtact acaaggacag gaacggttgg
     8761 acaaagcttg gcgacacaac aggcacgact atgcttgata tgaatgttgt ttcaaaggaa
     8821 tttgatttaa gcgttgacga tatttattac acggttcgct gtatcagcaa ggatgccaag
     8881 agttttacaa gcggatacga ttcaaagggt acgcccattg gcgatcatca ggattgtccc
     8941 gaaatttaca gcattggtgc agtaaacaac ggtgttgaaa tgcattggac gggagatgcg
     9001 ccaaagttcc gtgtttatat taaagaaaac ggttcttgga agaagatagc agaaacttat
     9061 gacaactatt atgttcacaa gggtgcaaag tccggcagta acacttatac ggtaagaggt
     9121 gtttcaaaag acggtaaaaa gtttactacg atgtttaacc caaccggtgt aacatacaga
     9181 tataagacat ccgataaaac aagggacgct tatatcaatt atatgatgaa tcataccgat
     9241 gaatggatgc caagcttggg aagtaatcac aatttgtcag gtgttatgtt tttggatttc
     9301 gactttgacg gagttccgga gcttgttgca caaaaggctg attccaaaga gtatggtttc
     9361 cattccgttg tttacaaatt tgaagacggt aagttaaaaa gagtgggaaa tgttaacgac
     9421 ggtttttcga tatactataa taaaactgcc aaaaagtatg aggttcacga cctggatata
     9481 tatttaaatg tagatgacgg ttactattgg acgggtaatt caataatcac atacgacgga
     9541 gagaatcttt ttgcaaatat gtattcggca agaggcgtag gcgaagaatc aaataataat
     9601 atttattata aatattttga cggtaatgac aaaaatattt cacgggcaaa atataacgaa
     9661 attaacctta agcagtttaa taattgcgta aatgcacata tgtttaccga atttattgcg
     9721 acaggttatg gtgataccag cgtgtggggt gagaaaacta ccgctgagaa taagcagtct
     9781 ttgcttgacg cttataattc tttctcctat gagaagtatt gattatttaa aaattgataa
     9841 gttttaactg caaaagggtt cagccgtaaa aagctgaacc cttttattgc acaacaaaaa
     9901 aacggttcag ccaaattgac tgaaccgtta attcgtacta tgtaatgctc gggtgacaga
     9961 agtttggata tatcaaacta acttcacgaa ctaaaaaata ttagttgttg atgagcttat
    10021 cttcgtcaga ccagctgtag agctttctaa cttccttacc gaatacttcg gcaggagctt
    10081 cggcagcgag ctttctcata gccttgaagt gaacctgtga acctgcatcg ctcatgtcaa
    10141 ggaggaagtc cttagcaaat gtaccgtcct gaatgtcaga aagaaccttt ctcatagcct
    10201 tcttagtatc ctctgtgatg atctttggac ctgtgatgta gtcaccgtac tcagctgtgt
    10261 tagagattga atatctcatg cctgcaaaac ctgactgata gataaggtca acgatgagct
    10321 tcatctcatg gatacactca aagtaagcgt ttcttgggtc ataacctgca tcgcaaagtg
    10381 tttcaaagcc tgcctgcata agtgcgcaaa caccgccgca aagaacagcc tgctcaccga
    10441 agaggtctgt ttctgtttct gttctgaatg ttgtttcaag aacgcctgct cttgcaccgc
    10501 cgataccgag tgcatatgca agtgcgagat ccttagcctg acctgtagcg tcctgctcaa
    10561 cagcaacgag gcaaggtaca cccttaccaa cctgatactc tgaacgaact gtgtgacccg
    10621 gtcccttagg agctaccatt gtaacatcaa catcctttgg aggcttgatg cagccgaagt
    10681 gaatgttaaa gccgtgagca aacataagca tattgcctgc ttcgaggttt ggctcgatgt
    10741 cgttcttgta aagagctgcc tgcttttcat cgttgataag aatcatgatg atgtcagcct
    10801 gctttgcagc ctctgccgat gtatatacct taaagccctg agcttcagcc tttgcccagc
    10861 tcttgctgcc tttgtaaaga ccgatgatta catcgcaacc tgaatccctt aggttgagag
    10921 cgtgtgcatg accctggctg ccgtaaccga taatagcaat tttcttaccc ttgagaaggt
    10981 caaggttgca atctgactga tagtagattg gtgctgtcat gttctttgtg tagtctttca
    11041 tattaaagtc ctccttaccg caaacgcggc atataaatta gaatatatgc taactgtaag
    11101 attaaacgga aaccgaagct gtgcctctgt caatggcaac agtacctgtt cttacaatct
    11161 cacggatacc ataaggcttg agtaagtcaa caagcgtgtt gacgcggctt gcacattcgc
    11221 agtactcaac ggtaactgac gaaggggata catcaacgat tttcgcctgc ataatttcaa
    11281 ccgttttgac aatttcagct ctttttgagg cggcgcagtg aaccttgatt aaaacaagct
    11341 cacggctgat aaattcgccc tcgttaagcc tttttacctt aataacggga atgagcttgt
    11401 tgagctgttt ttcaagctgt tcaacaatgt actcgtcacc gtttgcaacg attgtgattc
    11461 gggaaaccga cgggtcctga gtaacaccta ctgcgagtga gtcgatgtta aaacctcggc
    11521 gagagaaaag tcccgaaatt tttgaaagaa cgcccgcctg attttcaaca agtattgata
    11581 atgtatactg cattttatca cctcattaaa ttgacggagt gtcggggtga acatcgcaaa
    11641 caagaatgaa cggtttttcc gaatcaacaa tacccttgat gatgttttca gcttccttgt
    11701 ttgaatgagc ctctgcatgg tcaatgccgt aagcatcggc aatcttcaag aagtcgggat
    11761 caccgttgag aattgttgcg gagtgtctgc cgccgtagtg tttgtcctga agttcacgaa
    11821 ccattccgag tcgtgcgttt ttcataatga tgattttaat tccgagctga ttgcctgcaa
    11881 tagtcgcaag ctcattaagc cccatctgaa aactgccgtc accgcagatt acaataacat
    11941 cacggtcggg tcttgcaaac tttgcaccga ttgcagcggg aattgagtaa cccattgtac
    12001 ccataccgcc tgttgtgagg aatctgccct cacgaatacg gaagttgttt gcacaccaga
    12061 tttgattttg tcctacatcg gcaacgagaa ttgcctttga gcggaacatt gcactgagat
    12121 gaccgacaag tgttctcggc tcaacaaagc cgtcaaaaac gggaggctca cggtaaaggt
    12181 cttttttcca gttctttacg gtttcgctcc acattgttgt aaccttgtaa tcgccaatgc
    12241 tgtcaagcag catattgatg acatttttca tatcgcctac aatcggaatt tccgttttaa
    12301 cattcttacc gatttcagca gggtcaatgt caatgtgaat tacctttgtg ttttcactca
    12361 tctggtcggg agccgcaaca gctctgtcgc cgagtcttgc accgcatacg attacaaggt
    12421 cggcttcgtg aagagcacgg ttggcaacag ccttgccgtg agtgccgagc attccgagat
    12481 aaagctcatg ctcgctgggc ataacaccga tgcccatcat agttgaaata acggggatac
    12541 ccgtagtttc tgcaaatttt tgaagtttaa gcttgatacc cgaactcagc acgccgccgc
    12601 ctgatacgat aacaggacgc ttgcttgcgt tgatggcctc aacagccttt ttaacctgaa
    12661 ttgcgtgtcc cttagtgttt ggcttgtaac cgataatgtt tacgctttcg ggatattcaa
    12721 aactttcaat ttcattttcc tgaatatcaa cgggaatgtc gataagtaca ggaccgggtc
    12781 tgccggttga ggcaatatgg aaagcctctt tgaaaactct cggaaggtct tctgttttgc
    12841 tgacgagata actgtgcttt acaaacggtt cacaagctcc cgtgatgtca gcttcctgaa
    12901 agacatctct gccgagaagg tcggaacgaa cctgacctgt aatggcaaca atcggaatag
    12961 agtccgtata ggcggttgca atgcctgtga tgaggttggt tgcaccggga ccggaagttg
    13021 ccacgcaaac accgggacga ttactgcatc ttgcatagcc gcttgccgca tgagcagcgt
    13081 tctgttcctg acgaacaaga atgtgggtaa tgctcgaatc gtaaacttta tcgtaaaatg
    13141 ggcagatagc cgcaccggga taaccaaaga ctatgtcaac gccctcggct tccaaacatt
    13201 ttaccataat ttcagcaccg ctgatcatta tgttttgtcc ctcctatcct ttttattgtg
    13261 agcaaaaggt gttttgtaac attaaatata cctttttgct ttaccgctaa ttatacaata
    13321 aataccttaa aaagtaaaga gcagtattgc ccataaatta aattttttgc aggattttaa
    13381 attattctgt catcgcctga aaaagatata ataaatgatt aacaacaaaa acaaaatgct
    13441 gaccaaaaaa gtatctgtat aagagtaata acaagaaaat tcccgaacag ttttacctgc
    13501 tcgggaacag taatgattgt tgagaaaatc aatatttctt tttgaggagt cttgcggcaa
    13561 tgagtacgca gactacgctg acgcctgtgt cggcgataac ggacatccag atttgtgcaa
    13621 gaccgaatgc ggcaaggata attacaagag ccttgattga gagggcaaag atgatgttgc
    13681 ccttgacagt gttgataaca cttcttgcaa ttttaattgc ctttggaagc tgtttgagtg
    13741 tgcctgatgc gagaactgcg tctgacgctt caatagcggc ttcactgccg aatcccattg
    13801 cgataccgca gtcgcttgcc gaaagaacag gggcatcatt gatgccgtca cccacaaagc
    13861 aagcaccctt ggattttgat ttcaagccct tgaaaagctc aagcttttga gcagggagaa
    13921 gctctgcgtg acattcggaa agtccgagtt catttttaac attttcggca ggctgttgtc
    13981 tgtcgcccgt gagcattacc gtgttcttga caccgagcgc tttaagctgt gagataacct
    14041 cttttgcctc aggccttact gtgtcgctga cattgagcga accgataagc tgaccgtcat
    14101 aaattacgaa aacagaatcg tctttgtttg caattttctt ctgttcgtcc gaaagaatct
    14161 ttgaaccgcc gcactgaata gttttgccgt tataaactgc gcttgttccg tgaccggcac
    14221 tttcgctgta gtcggaaagc tcgggaagtt taagaccgtt tgccttttct ctgattgcgg
    14281 aggcaatcgg atgagcggaa tatttttcgc ttgcagcggc aagagcaaga acttcgtcag
    14341 cactgtatga accgaccgta ttaaccttgt ttactctgag cttgccgctt gtgagcgtgc
    14401 ctgttttatc gaatacgaat gtgtctgctt ttgcaagagc ctcaatatat tttccgccct
    14461 tgatgagtac accgacttcg gatgccgcac cgatacccga atagtaggag agaggtacgg
    14521 aaataacaat agcacacgga catgacgcta caagacaaac aagtgcacgg tatagccatt
    14581 cgctgaatgc tccgagtccg caaagcggag ggattactgc gattgcaact gcaatgagta
    14641 caacaaccgg tgtgtaaacg gaggcaaatc ttgaaataag cttttcgctg ttgccctttt
    14701 gagcggcggc atcttcaaca agctgaagaa ttcttgttgc ggtactgtcg ccgaaatgct
    14761 ttgtggtttt gacggtaata aggttgctgc cgttgattgc gccgctgagt acctcactgc
    14821 cctcgcctgc atcaacagga aggctttcgc ctgtgagagc agatgtgtcg agagttgttt
    14881 tacctttaat aataatgccg tcaagcggaa ctctttcgta tggcttgact tcaatgatac
    14941 ttccgatttc aacgctttcg gcaggaacaa tctgttccgc actgtcaaca ataattgttg
    15001 ctgtatcggg acgaatgttt gcaagctttt caatgtcacg gcgggatgcg tcaactgctc
    15061 gatcctcaaa aatttcaccg atagaaaaga gaattgttac cattgccgcc tcaacaaaat
    15121 ctccaagaca gaatgccgca attaccgcaa cagccataag tgttgtttcg tcaattctca
    15181 gctttagaat gttttttgca cccttgatga ataccttgta acccgaaaga attgttgcaa
    15241 caaaacacgc tgcgagtaca acataatgaa cagccgtaac accgtcaagt gtaaggtgga
    15301 gaatttcgga cactacagca agtacaattg aaattgcaag gaagattgtg tcatgattga
    15361 ttttcttttt cgtgatttcg gggtctgcct ttgttgtgat atcatttttc ggagttttgt
    15421 caacaacagt tacaccgtcc tcaatgctgt cgcaaattgc ctgaatttcg gaaacaggat
    15481 tctgcttttc gcttttgaag ttgagaagct ttgtcgcaaa gttgaagttt acatcctcaa
    15541 agccgtctgt ttctgcaatt ttagcctcaa ttttgcctgc acaatgagcg cagttgagat
    15601 tgtctaaagt gtaggtgtat tttttgagat cggttttcgg agttttgtca acaacagtta
    15661 caccgtcctc aatgctgtcg caaattgcct gaatttcgga aacaggattc tgcttttcgc
    15721 ttttgaagtt gagaagcttt gtcgcaaagt tgaagtttac atcctcaaag ccgtctgttt
    15781 ctgcaatttt agcctcaatt ttgcctgcac aatgagcgca gttgagattg tcaagctgat
    15841 atttgtacct catatgtttc ccccttattc aagaacatgg tcaagtccca tttcgatgat
    15901 tcgtttcaca tggtcatcgt caaggctgta ataaatctgt tttccttcac ggcgaacacg
    15961 caccagcttg ttctgcctta atacacgcag ttggtgggaa attgtacttt gctccatgtt
    16021 gagagcttca gcaatgttga gcaccgacat ttcattttca gaaatggtgt acataatgcg
    16081 aagtcgggtt gaatcaccga aaaccttaaa aagatctgca agctcaaaca gcacatcaat
    16141 gtcgggcatt tcgggagttg tgactttttc tttttcgttt tccatagcca ttctcctcaa
    16201 tattttatgt ttaatcaatt attacgattg aacatatgaa gatgtgttca tatgttgatt
    16261 ataatataac atctcttttt gcaaaagtca atagacacag aagaaaaagt gtaatatttt
    16321 tcaagatttt ttgccttaat atttcgcttg tttattgcat tcgtttggag agtatatata
    16381 atatagtata gggagaggat tttaaaatac tcaaaagctt ggcaatgaca tataaataac
    16441 acttatttca atttgtaata attctacaaa aaaatctctt gaattattac ctctttttaa
    16501 gaaaaatcaa ttcaaaaaat gatgcttggt tataataaaa acaaaaacag caaggaatca
    16561 acaaattgag tacaacttgc ccaaaaatag attacagttt tattattccg ttgactttac
    16621 tacaattttg tagtatcatt ttctgtagga gaattgtata gttacatctg cgtaaccgag
    16681 caggttcctt tttaataaaa tgtaacaaat tagttctcat tccgaatttt agattcgtgt
    16741 tatttttgat ttttacttat ttagatatat atttcagata ttttttaaat atcttctaca
    16801 cataattggg gtgtaacaat tggagaagtt cgtagttacc ggcggaaagc cattatcagg
    16861 tgaagtgaca atcagcggtg cgaaaaatgc agccgttgca attattccgg cagttattct
    16921 ttgtgatgaa ccctgccaaa tagaaaatat tcctaacatc agcgatgtat cgctcatcag
    16981 cagaattctt cagcagatgg gtgctaatgt aagacgaatc aaccgttcat ctttgtatat
    17041 tgaccctaca aaaatccgca cttgcaatgc ggttacagac cttgtaagag gtatgagagc
    17101 atcatattat cttctcggcg cacttttggg caaatacggc aaggcaaagg ttgctcttcc
    17161 gggcggctgt aactttggtg tgcgtccaat cgaccagcat ctcaagggct ttgaggctct
    17221 cggagcaaca actcagcttg ttgacggtgc aattattgag gcagaatgtg agaatcttgt
    17281 gggtacgcat gtgtaccttg atgttgtatc agttggtgca acaatgaaca ttatgcttgc
    17341 cgcttcaaaa gccaagggtc agactattat cgaaaatgcc gcaagagagc cgcatattgt
    17401 tgaccttgca aacttcctca actcaatggg tgcggatgtc agaggcgcag gtacggatgt
    17461 tatcaaaatc cgtggcgttg agtatcttca cggcattact tattcaatta ttcccgacca
    17521 gattgaggca ggaacatata tgtgtgccgc agccgcaaca agaggttgta ttacggtaaa
    17581 gaatattaca ccaaagcatc ttgaatcaat cagtgcaaag ttgcgtgaaa tgggtgttaa
    17641 gattacagag tatgacgagg ctctcaaggt tgatgcttca tctgctccgc tcaagcgttg
    17701 caatatcaag acaatgcctc atccgggttt cccgactgac tgtcagccac agtttgccgc
    17761 attgctcatg agcgttcccg gcacaagcat tattaacgaa aatgtttggg ataaccgcta
    17821 tcagtatgtc agcgaactcg tgagaatggg tgcacagatt tctgttgaag gcagacttgc
    17881 aatcattgag ggcggtactc cgcttacagc agctcccgtt aaggcaacag accttcgtgc
    17941 aggtgcggct atgattattg ccgctcttga aatcaacggt acaaccgaga tttcaaacat
    18001 tcagttcatt gagcgtggat atgaagatgt tgttgaaaag ttcagagcgc ttggtgcaga
    18061 catcaaaaag gtgtatttca caggtgacaa cgagcaggag ctcggtgcct gatttaaaac
    18121 ttaattaaaa agcaaagccg ttttctttgt gagaacggct ttttatgtgc aatgaaattt
    18181 acaaatttta aaatttgtgt tatcatattt ggcagactat agataaggat tgattgtttt
    18241 ggcaagagca gtgccgctgt tcagcggaag taagggtaac agttactaca taggttcggc
    18301 aaccgagggt gttttgattg acgcaggtcg ttcgtgcaag cagattgaaa atgcaatgct
    18361 tgcaaacgga attgatatga gcagtatcgg ggcggttttt ataactcacg aacacacaga
    18421 ccattgcagt gcgttgcgtg tgcttgcaaa gcgttacggc tttaaagtgt attcaagtct
    18481 tggtacgctc aatgctttga gggcaggtaa taagcttgat ccaaacacag atgcagatgt
    18541 tataacagac gaggttgtaa tcggcaatat gcgtgttcag cgatttgaca caccgcatga
    18601 tacggctgaa agctgttgct accgagttac cgctcctgac ggaaaatccg cacttatagc
    18661 aaccgatatg ggtgttatgc tgtctgatgt cagaactgcc gcagagcaga gtgactttgt
    18721 tgtgcttgaa tcaaatcacg atatcaatat gctcaaaaac ggattttatc cttatccact
    18781 taagcaaaga atcctttcaa acagaggaca cctttcaaat gaagcgtgtg caaaggaact
    18841 tgtcaacctt gttgaaaagg gaactttaag gcttatgctc ggacacttga gtgaagaaaa
    18901 taataccgtt ccgcttgcaa tgtcaacatc cgttgacctg ctcacatcaa acggaatgaa
    18961 gtacaaaagt gactattcgc ttgatgttgc accgagtatc agcacaacca aaactatcat
    19021 cttttaacta taaataagcg agaaaaatat gattaagatt aacataattt gcattggaaa
    19081 aatcaaggaa aagtatttta ccgacgcaat tgcagagtat gcaaaacgct tgaccgcttt
    19141 ttgtaaattt aatattgttg aactttcgga agaacgcata aagagcaaca ctccgaatca
    19201 gtcgcagatt gacgaggtta tttcttccga gggaaaacga attatgcaga aaatttcacc
    19261 ctccgactat gttgtcgcaa tgtgcattga gggcaagttg atgtcaagcg aagagctttc
    19321 aaagctgatt gacaacgctt ccgttagcgg aaaaagtacc gttgatttta ttatcggcgg
    19381 aagttacgga cttgacgaat cggttaagaa aagggcggat gttcgccttt cgatgagcaa
    19441 aatgaccttt ccgcatcaga tggcaagaat gattttaagc gaacaaattt accgtgcatt
    19501 tgagatttca tcaaatggta aatatcacaa ataatttacg gagttactat ggcacttgac
    19561 ggaatttttt taagacatat taaaaatgaa atagaaaaag aggctctcgg tgcaagagtg
    19621 tcgcagattt atcagccaaa cagggaagaa ctcgtgttcg gtctgcgaac attttcgggc
    19681 aacaaaaagc tgttgctttc tgcaagggca aattcaccga gggtgaactt ttgctcttca
    19741 acacctgaaa atcctgcaca accgccaatg ttctgtatgc ttttgagaaa aagaatcggc
    19801 ggcggaaaat tggtgggact tcgccagaac ggttgcgacc gtgttcttat gctcgacttt
    19861 gagtgcgtga atgaactcgg cgatacggtg atgataaccg ttgtctgcga aattatgggt
    19921 atgtacagca acataattat tgttgattca aacggtgtta tcatcgactc gctcaagcgt
    19981 gtagatctta caatgagcag taaaagactt gtactgccaa atataaaata cgaacttccc
    20041 gaatcgcaga acaagctgaa tctccttgaa tgtactgcac ttgatgtgtg tacgacggta
    20101 aaaaatcttg acacggaaat gccgcttaac aaggctcttt tgagaacgat tgagggtgtt
    20161 tctccgattg tctgccgtga gattgaatat aaggttatgg agggcgcaac caacagaatt
    20221 gaaggtgtgc tttttgaccg actcgcagtt gaaatcgaaa agctgaaatg cgtttgttcc
    20281 gactgttcgg gaaagcctgt tgtggtttac cgtgaggacg gcaagcctat ggacttctgc
    20341 tttatgaatg ttgagcagta cggcgatttt gcaagggttg aggacaggga aagcttctcc
    20401 gatttgcttg acggattcta tgaggctcgt gacagtcgtg accgaatgag ggtgaaatcg
    20461 caaagcctta caaagctttt gaacaatacc cttgaaaggt ttgcacgaaa gattgtaaaa
    20521 cagcagagcg agcttgaacg ctgtgcagac cgtgagcatc ttcgcatatg cggtgacctt
    20581 ttacaggcaa atatctatcg cattgagcgt ggtgcggagt atgttgatgt tgaaaacttt
    20641 tacgatgaga acaacgcaat tttacgcata aagcttaatc cggcaatctc accttcggca
    20701 aatgctcaga agtattacaa ggattaccgc aaggctaaaa atgccgaaat tatgctcaaa
    20761 gaacagcttg aaaagggcag agaagagctt gattatatag actccgttct tgatacggtt
    20821 gaccgtgcag agaatgaaaa agacctttcg caaattcgtg aagagcttac cgagcagggc
    20881 tatctcaagg ttcaaaaggg caaaaagccc cgtcagacaa ctttgccgcc gcttgaattt
    20941 gaatcaagtg acgggtttaa aattcttgtc ggaagaaata accgtcagaa tgataagctg
    21001 actttgaaaa cagcgtcaaa gaacgatatg tggcttcata caaaggacat tcacggctct
    21061 catgtaattg ttgtttcgga cggcaaagag atttccgaca cggcaatttt tgaagcggca
    21121 cagcttgcgg catatcacag caaggcgaga aacagcagtc aggttcccgt tgactacaca
    21181 ctcgttcgct atgtgtcaaa acccaacggc tcaaaacccg gtatggtgat ttatgtcaat
    21241 aacaagacgc tgtatgttaa gccgtcacag acaattgaaa agcagaaaat tcaataaaag
    21301 aattaaacgg agagcgtttt gccctccgtt tttttgtatc aaaaataaaa aatcggttta
    21361 aattgaataa tatattccaa aagcgacagt gattaacctc ccgcttgttt ttattaaacg
    21421 caaatttgca ctcacgccta aaatctttta ttagttccat aaaagaataa ataattgtaa
    21481 tttatttaaa attgtaaaaa atacatacta atagtattaa ctaaatcaag aaaatactat
    21541 tgataataac taaatgtgtg atataataag cacggaaggt atagcagcaa tctaaagtat
    21601 ttatgagcgc ttattatatg aatttatgtt cccttaaaat cttgccttgc aaaattctcg
    21661 atgggtgatt atgatataaa tttctttgga ggtgattata tggattatat tgctcatgct
    21721 acgccggata ataggacgca gacagtgatc gaacatagcg taggtgtgtt taataaaggc
    21781 aaatcggatg cggaattgat atctgctttg aatttatata aattgtgcag ttgcttgcac
    21841 gatatgggta aaaacacatt aaaaagcagt gagtatcaaa aaactgtcgg tttgggtaat
    21901 aagtggagcg gtggaaaggt tgttcattca aactgtggcg gaagatttat ctatgaaaca
    21961 tttattgaaa acaatgataa tcttgatgaa tttgacgcct taaccgctga atttattgca
    22021 acggtaatta tgtcgcatca cggacttttt gacattttga aaccttacga tgataaaggt
    22081 cttaattatt tcatcgaaaa attacataat gacagttatg attatgcgga gtgtaagaaa
    22141 aaaacacttg ctgaattttt agacttggat acaatcaagc agattttttc aatggcaaaa
    22201 gatgaaataa aagcctttga atccgaaaac gaatatcaag acagcaggat gaataagttt
    22261 agccgttcaa tgtttgtccg tatggtgctt tcaattctga ttaacagcga tcatgctgat
    22321 gctgcagatt ttgcttataa aaccgacact catgatgagt atgtagacag tgaattttgg
    22381 aaaaagtgtt ctgactatct tgaagaaaaa ataacgcatt ttaaaaatga tactttactc
    22441 aataaaataa ggtcagaaat ttcaaacaaa gcctacgaat tttcatctca acccgccgga
    22501 atagtgagaa tgacagtccc tacgggagga ggaaaaacaa tttcttcttt aagatatgcc
    22561 gttcatcatg cggaaaagtt taataaacga agaattatat atgttgcacc ttttaattct
    22621 atattagaac aaaattgtct tagcattaaa gattatttgc ccgaagatgt tactatttta
    22681 ccgcactttg gcgattggat tgacaaaaaa gactcggaat ccgaaagttc agaaaacact
    22741 ctgaaatata tttcagaata ctggggtgcg ccgataatag ccacctcaat ggtgcagttt
    22801 ttaaattctc tttttgacgg caaaattact tctctaagaa gaatgagagg tcttattgat
    22861 tctgtcataa taattgacga ggtgcagtca attcctattg attgtcttgt tatgtttaat
    22921 cgtgctgttg atttccttgc aaagcattgc aaatgtacag tcgtactttg tacagcaact
    22981 caaccgcctt ttgaaaaact taaagagggt tttgttttac ccgaaaattg cgagatgatt
    23041 gacgaatttg cccattactc tcagcttatg aaaaggactc aaataattga taaaattaaa
    23101 cctcgtggtt acgattctga aaaagcggca gattttataa ctgatttgct tgaaaataat
    23161 gacagcattt tgtgtgtagt gaatactaaa aatgccgcaa ggtctatata caaagaggtt
    23221 gatttaaa
//
