LOCUS       c00189_gnlPro..        10280 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HGHCECKN_189.
ACCESSION   c00189_gnlPro..
VERSION     c00189_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 21:19:35
            Original ID  :: gnl|Prokka|HGHCECKN_189
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10280
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10280
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1791:6348]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1792..6348
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..10280
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10280
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(2..169)
                     /locus_tag="ctg189_1"
                     /transl_table=11
                     /translation="MKKGLHPESYRPVVFKDMSNGDMFLSRSTVATKETIEFEGETYPL
                     LKIEISNTSHP"
     CDS             603..1607
                     /locus_tag="ctg189_2"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPQEEVATINKYGGALKAAIGIPEEWLRKAAKSAVCKINIDSD
                     SRLAMTAAVRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAQ"
     CDS             complement(1792..2952)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg189_3"
                     /sec_met_domain="OAD_beta (E-value: 5.1e-154, bitscore:
                     501.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATVGHVVMILVGLVFIYLAIAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKNERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFVIATASGVIFVKIFNIFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDSTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(2954..3385)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.7; E-value:
                     2e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg189_4"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.9e-22, bitscore:
                     67.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKPV
                     AKPVTVRPMPNAPAAPTQVVKPTAPSTGKSGVKSPLPGVILDIKVNVGDTVKKGQTIII
                     LEAMKMENNINADKDGKITAINVNKGDSVLEGNDLVIIE"
     CDS             complement(3410..4330)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg189_5"
                     /sec_met_domain="OAD_gamma (E-value: 5e-16, bitscore: 48.5,
                     seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLVLNEILIDNQSNFQD
                     DYGLHSAWIEIFNKSFGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGKKLLDQIVVPAGALGPNQSYARVSDGAAEW
                     EVKSGSGDKYVTPSTNNKTLDSNSKMEKFEEHDADGVGMSISAMSVVFCGLILLFIAFK
                     IVGKVAVNLSKRNAMKSKGIDKHEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRETPPRK"
     CDS             complement(4362..5915)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg189_6"
                     /sec_met_domain="CT_Btheta (E-value: 1.4e-290, bitscore:
                     953.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERLAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYVFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGFELIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPT
                     KPYDMYEVIGAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             complement(5944..6348)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg189_7"
                     /sec_met_domain="Glyoxalase_4 (E-value: 9.5e-25, bitscore:
                     76.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             complement(6524..7522)
                     /locus_tag="ctg189_8"
                     /transl_table=11
                     /translation="MPLKLTTYYHGKDIPELPGKNAFHSKELFQIYEATPGYTPLLIVA
                     TEDGRPVARLLAAIRKAKKWLPSSLVKHCVVYSEGEFLDESLSTNKEKAEEVFGDMLEH
                     LTQEASRSCVLIEFRNLNNSMFGYRVFRANDYFPVNWLRVRNSLHSMKKTEDRFSPSRI
                     RQIKKGLKNGAKVEEAHTVEEIHDFSRMLHKVYSSRIRRYFPANDFFRHMNDMLIKGQQ
                     AKIFVVKYKEKIIGGSVCIYSGDDAYLWFSGGMKKTYALQYPGVLAVWKALEDARQRGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRVNWNWLNKLLVKFYV"
     CDS             7762..10278
                     /locus_tag="ctg189_9"
                     /transl_table=11
                     /translation="MRCNAFVEAWKNYHRRASMILGLSLLAAPLSYAVYAEDGVSNTMV
                     QVVTQTKTVKGTIIDESGEPLIGVSIVVKGTSTGTITDFNGNFSIDLPAGRKELVISYI
                     GYKEQTVTVTGNGPVNVKMVSDTQALDEVVVVGYGTMKKRDLTGAITSVKSEDVVMNPS
                     SNPMQALQGKVAGLDITRESGQAGSGVKMQLRGNRSFQKDSGNPLFIIDGMPGDYSTLN
                     PNDIESIEVLKDASSTAIYGSSGANGVILITTKGGKEGKAIVNFNAYVGVNGWSRTPEM
                     RSGESYIQTLRDASVGAGDGRWSSVADDKNLFTTDAEWNAHQNGQYIDWVDALLKTSVT
                     QNYSVSVAGGTEKTKAYFSLNFSNEDGQFAQDSYKLYSSKIRVDHKIKKWMKVGIDAQL
                     SYVHQNKADSDLQTLMASNPLGSLYNEDGSINPQPVADPSSTVYNYLLNEDKSLYRNQA
                     QNLKVYFNPYLEITPLKGLTFITRAGASLGYSRSNTFTGEGSVQWYKANQTADGIKAQV
                     KDNRSYNYKWENILTYNFQIKKVHDITLTAVTSWNHNRSDVTTLYQKGVSDNKFLWHNI
                     LDGNSATSGSTSYSMSKGMGYVGRLNYSYMGRYLFAASVRHDGSSRLAEGNKWDTFPAF
                     SLGWRISDEKFMESTTNWLSNLKIRFGYGVTGSTAGIDPYSSAASLDATAVNMILGGVL
                     TPIYKFSQNIPNYLLTWEKSYNTNIGIDAAFLNNRIDVSMEYYNTKTKDVIWNKALPVI
                     NGAFSPDGGPKANYTTNLNMCETSNKGFELALNTRNIITKNFTWSSSVTFNHNKEKITK
                     LSGGDSDVLNNGDTGYALALGEAINSY"
ORIGIN
        1 acgggtgaga agtgtttgag atttcaatct tcagcaacgg ataagtttca ccttcgaatt
       61 cgatggtttc tttagttgct acagttgatc tagacaaaaa catgtcacca tttgacatat
      121 ctttaaatac taccggacgg tatgattctg gatgaaggcc ttttttcatt tcagtatctg
      181 tttttttaat ttatattctg ttactatttt ggtaagaaat agtgtaatgg tcattttcag
      241 agcgcaaaga taatgctttt ctgtgaaata gaaaaaggtt ttctaaaatt tctgatttct
      301 aatttatgat ttctgatttg ctatgcagat tttgatgatt aaatgaatga aaaatgaggt
      361 ataaataagg tataaataag gagatataaa tccgaaggca tcaatcagaa ttcagaaatc
      421 ataaatccca aagtttgcaa ggtggacatt acaatctaat gtcacactcg tattcctgct
      481 aaattttgca gtctgattta aacctttttc tactatattt ttctttccga tgttcgttat
      541 tcgatggata atgcttactt ttgcgtagaa tttttattca ctaacaataa actttaaaca
      601 aaatggtaaa ttacaaagat ttaggattgg taaacacaag agaaatgttt gctaaggcta
      661 tcaaaggtgg atatgctatc ccagcattca acttcaacaa tatggaacaa atgcaggcta
      721 tcatcaaggc tgctgttgaa actaaatctc ctgtgattct tcaggtttct aaaggtgctc
      781 gtcagtatgc taacgctact ttgttgcgtt acatggcaca gggtgctgta gaatatgcta
      841 aagaattagg ctgcgcacat ccggaaatcg ttcttcacct tgaccacgga gatacattcg
      901 aaacttgcaa atcttgtatc gattctggtt tctcttcagt aatgatcgat ggttctcacc
      961 ttccttacga agaaaacgta gcattgacta agaaagttgt tgaatacgct caccagtttg
     1021 acgtaactgt agaaggtgaa cttggcgtat tggctggtgt agaagatgaa gtttcttccg
     1081 accatcacac atatactgac cctgaagaag taatcgactt cgctactcgc actggttgcg
     1141 actctttggc tatctcaatc ggtacttctc acggtgctta caaatttact ccggaacaat
     1201 gccacatcga cccgaagact ggccgtatgg ttcctcctcc attggctttc gaagtattgg
     1261 acgctgtaat ggaaaaactt ccgggattcc ctatcgttct tcacggttca tcttctgttc
     1321 cacaggaaga agtggcaact atcaacaaat acggtggcgc attgaaagct gctatcggta
     1381 ttcccgaaga atggttgcgt aaagctgcta agtctgctgt ttgcaaaatc aacatcgact
     1441 ctgactctcg tctggctatg actgctgctg tacgtaaggt attcgctgaa aaaccggctg
     1501 aattcgaccc acgtaagtat cttggcccgg ctcgtgacaa tatggaaaaa ctgtacaagc
     1561 acaaaatcat caacgtgctc ggttctgaca acaaattggc acagtaataa tctccggatt
     1621 attccataaa taaaagaaag aggctgctcc ggtttgaaca ctggtagcag ccttttttat
     1681 gacgtttaat cgtttcagaa cggagagaag ataacactat ggctgtaata aagaacaccc
     1741 gtgtcacaac tgaatgtaac acgggtgttc ttatctatta tataatgttt cttacatcaa
     1801 gaatccaagc agaataccgg cagcaacagc tgaaccgatc actccggcaa cgttcggacc
     1861 catagcgtgc atcagcaaat agttggtcga atcatattcc aaaccaatca cttgcgagat
     1921 acgtgcagag tcgggaacag cagaaacacc tgcattaccg atcaacggat tgatcttatt
     1981 acccttcttc aggaagatat tgaagatctt aacgaagatg acaccggatg ccgttgcaat
     2041 aacaaatgac aatgcaccga gggcaaagat cttgatagag tcaagcgtca ggaattcgga
     2101 tgcttgtgta gaagcaccta ctgtcagacc caacaggata gtgattgtat caatcaacgg
     2161 accactggca gtattagcca aacggcgggt tacaccactt tctttcaaca ggttaccgaa
     2221 gaacagcata cccagcaaag gcagaccgga aggaaccagg aaacaagtca gcaacaaacc
     2281 gatgatcggg aaaatcacct tctccgtgtg agaaacggca cgcggcggtt tcatgcggat
     2341 gacacgttcg ttcttggtgg tgagcagacg catgataggc ggctgtatca ccggaaccaa
     2401 cgccatatag gagtaggcgg acaccgcaat ggctcccatc aggttaggtg ctagcttgga
     2461 agaaaggaag atggccgtcg ggccgtctgc tccaccaatg ataccgatag caccggcttg
     2521 catcgggtcg aagcccattt ctaacgcgat catataagca ccgaagatac cgaattgtgc
     2581 agctgcaccg atcagcatca attttggatt agagataagt gccgagaagt ccgtcatggc
     2641 accgatgccc aaaaagatga gcggcggata ccagccggag gtcactccct gatacaatat
     2701 attcaataca gaaccttctt cataaatacc gactttcagc ccggcatcca tattaaaagg
     2761 tatattaccg atcaatatac cgaaaccgat aggaatcagc agcatcggtt cgaactcttt
     2821 ggctattgcc aaatagatga ataccaagcc aacgagaatc atgactacat gccctaccgt
     2881 agcattggca aagcctgtgt atgtccagaa gtcggccagg ttatttccta aaaagtttat
     2941 aaagtctccc atattattca ataattacga ggtcattacc ttcaagaaca gagtctccct
     3001 tgttgacgtt gatggcagta atcttaccgt ccttatccgc attgatattg ttttccatct
     3061 tcatggcttc caatatgata atggtctgtc ctttctttac agtatcgcct acattcactt
     3121 tgatgtcgag gatcacaccc ggcagcggag attttactcc tgattttccg gtagacggag
     3181 cggtcggttt cactacttga gtaggagcag caggagcatt aggcatcggg cgtactgtca
     3241 cgggtttcgc aacaggcttc ggctgtttct ccatttctac tttatagtgt gtaccgttca
     3301 cttctacatg agcgatgttg tcttcaatat ctccgatggt tactttatat gagttaccgt
     3361 tgattttata tttatattct ttcatcgttt ttacttttta aaaggtgact tactttctgg
     3421 gaggagtttc acgcaaagtg taaatcttcg aactccatgg tgagtagctg cgttttacgc
     3481 gggtgatggt cagcaccgtt tcttctacgt cgtgcacctc atcctgcatt tcgtgtaatg
     3541 ccatagaaat agcagcgtat acttcgcccg gagcctgtga cagttcctta gcttcatgct
     3601 tgtcaatgcc tttagatttc atagcgttgc gcttgctcaa attaacagct acttttccta
     3661 caatcttaaa agcaataaag agaagaatca atccgcagaa tactacgctc atggcagaaa
     3721 tggacattcc aacgccatca gcatcgtgtt cttcaaactt ttccatcttg gaattgctgt
     3781 caagagtctt gttgttggtg ctcggagtca cgtatttgtc accgcttcca ctttttactt
     3841 cccattcagc tgccccgtcg cttacacgag cgtatgattg gttgggaccg agcgcgcctg
     3901 caggcactac aatctggtcg agcaacttct tgccggagtc gaacagacct acccagttag
     3961 ctgtttccgg attcagcttg aagctggtat ggaaagtacc acggttaggt tcgccatctg
     4021 cccagaatag tgcatgttgg cgtggtttca ctaaggtaag tatatcacct ttcgggataa
     4081 aataagtaac tgtatcgccc ggttggctgc ttactttcag caagcaagct gccaggtcgg
     4141 cgctaccgaa tgatttattg aatatttcaa tccatgcgct gtgcaatccg taatcgtcct
     4201 gaaaattact ctgattgtct atcaggattt cgtttagcac cagcttattg ttcgactttt
     4261 gctctccaca agaagtcaga ccaatcagca acagcaaaga aaggaatatt ccgattttgg
     4321 ttttgttcat aatcgttctt gttttaatgt gaaaagtagg attacaacgg aatattacca
     4381 tgcttcttag ccggattgct caatttctta gtctgcaact gctgcaaagc acggatcaca
     4441 cggaaacgtg tgttgcgcgg ttcaatcaca tcgtcgatgt agccatattt agctgcattg
     4501 taaggattgg cgaacaattt cgtgtattct gcttctttct ctgcaaggaa ttgagcaggg
     4561 ttttcctgat ctttggcttc gcgtgcgtac aatacttcta ctgctcctgc accacccatt
     4621 actgcaattt cggcagtagg ccatgcatag ttcatgtcac cgcgaagttg cttacagctc
     4681 attacgatgt gagaaccacc gtaagattta cgcaatgtga tagtaacctt aggcacagta
     4741 gcttcaccgt aagcatacaa cagtttagca ccatgaagga taacgccatt gtattcctga
     4801 cctgttcccg gaaggaatcc cggtacgtct accaacgata cgataggaat attgaatgca
     4861 tcgcagaaac gaacgaaacg tgcaccctta cgagatgcgt tgctatcgag cacaccagcc
     4921 agatacttag gctgattagc aacgatacct accgattgtc cgttgaaacg ggcgaaaccg
     4981 atgatgatat tctttgcata atctttctgg atttcaagga attcaccgtt gtccacaata
     5041 gcgccgatca cttcgtacat gtcatacggt ttagtagggc tgtcggggat aatatcgttc
     5101 aaagaatctt ccagacggtc gattgggtct gtgcaatcta cataaggagc ttcttcaagg
     5161 ttgttttgag gaatatagct caacagtttg cgaatcagtt cgaaaccttc ttcttctgtt
     5221 tgggcggtga aatgagtcac acccgattta gtggagtgaa cgcttgcgcc accgaggttt
     5281 tcctggctaa cgtcttcacc tgtaacggtc ttcaccactt tcggtccggt gaggaacata
     5341 taagaagtgc cttccatcat cagtgtaaag tcggtcagag ccggagaata aacagcacca
     5401 ccggcacaag gaccgaagat accggaaatc tgcggaataa cacctgaagc aaggatgttg
     5461 cgttggaaga tttctgcata acctgccaaa gcgttgatac cttcctggat acgtgcacca
     5521 cccgagtcgt tgataccgat acaaggagca cccatcttca tggcctgatc cataatttta
     5581 caaatcttca atgacatcgt ttctgacagt gaaccggcag aaacagtgaa gtcctgtgcg
     5641 aacacatata ccagacgtcc ttcgattgta ccgcagccgg ttactacacc gtctcccgga
     5701 taatgttttt tctccattcc gaagttcgtg catctgtgct caacgaacat gtccatttct
     5761 tcgaagctac cctcgtcaag cagcatagcc aaacgctcgc gtgctgtgta tttccctttt
     5821 tcatgttgct tcgcaattgc tttttcgccg cctccgatac gtgctacggc acggcgttca
     5881 ataagctctt taattttttc aagttgatta ctcatgagtt cttgttggtt ttagagttta
     5941 tgattaatgt tcgcagagtt ctgtcaacac gcccaaagtt gatttcgggt gaaggaaagc
     6001 aatattcaaa ccttcggcac ctttgcgggg agctttgtcg ataaggcgga tttctttgct
     6061 ttctgcttct gccaaagcat tggctacgcc atcttctaca gcaaaggcaa cgtgatgaac
     6121 acctgcacct ttgttttcaa tgaatttggc aatagtactc tccgggcaag tcggctccaa
     6181 cagttcaatt ttggtttcgc ctacttttaa aaaagcagtt cttactttct gatcttccac
     6241 tgtttcaatg ttgtaacact tcagacctaa tacattttcg tagtaaggaa gggcttcttc
     6301 gatgcttttt acagcaatgc ccagatgttc aatgtgtgaa atcttcataa ctatactttt
     6361 tttatttggt tttaatcatg tgcttatatg gcataaaaca gcacaaagaa agacatttct
     6421 tacctaataa agaaatattt ctgcatttaa ttattggatt attaaacaga aaaaatggta
     6481 gggaaggagc atgaagagtc gttttgcaat cttgagatta catttagaca taaaatttga
     6541 ctaagagttt gttcagccaa ttccaattga cacggaacca gcggcgggta ctgctttgct
     6601 ttcctccgaa tcggagaacg aaatcacgat aaccgtgttt gcggaacgga agtcctacat
     6661 ccataaattc catgtgacgg aatccccgtt ggcgggcgtc ttccaatgcc ttccaaacgg
     6721 ccagcactcc cggatactga agtgcgtatg tctttttcat tcccccggag aaccaaaggt
     6781 aggcgtcatc tcccgagtag atacagacgg aaccgccaat gattttctct ttgtatttta
     6841 ctacgaatat ttttgcctgc tgtcctttga ttagcatatc gttcatgtga cggaaaaagt
     6901 cgttggcagg gaaatatctg cgtatgcggg aggaataaac cttgtgcagc atccgtgaga
     6961 aatcgtgtat ttcttccacg gtatgtgctt cctctacttt ggctccattc ttgagtcctt
     7021 tttttatctg acggatgcgt gacgggctga accggtcttc cgtctttttc atactgtgca
     7081 gcgaattgcg tacccgcagc caattgacag ggaaataatc attggcacgg aaaacccggt
     7141 aaccgaacat cgaattattg aggttccgga attcgatcag gacacagcta cgcgatgctt
     7201 cttgtgtgag atgttcgagc atatcgccaa agacttcttc tgccttttct ttgttggtcg
     7261 aaagcgactc atccagaaat tcaccttcgc tatatactac gcaatgtttc actaaagagg
     7321 agggaagcca ctttttcgct ttgcggatgg cagcaagcag gcgtgccaca ggtctgccgt
     7381 cttctgttgc cactattaat aaaggagtat accccggagt cgcttcataa atttgaaata
     7441 actctttgga atggaaggcg ttttttcccg gcaattcagg aatgtccttc ccatgataat
     7501 atgtggttag tttaagtggc atctaggtac aaatttacac tttttattct ttattcaaca
     7561 acaaaacaaa gattttgttg gaactgcctg aagtaaagta caatatatct ttgcatattt
     7621 aatggaaaaa atgtatttta taggagaaat atggtatgaa aagtgagtac gtattaaaat
     7681 tatgttcgtc ttaaattaag attataatcg aatagttttt gcaaaacaac gagaattaat
     7741 attaacttta aattagaacg aatgagatgt aatgcatttg ttgaagcatg gaagaattat
     7801 catagacgcg cttccatgat tttagggttg tctttattgg ctgcccctct gtcatacgct
     7861 gtttatgcag aagatggagt ttctaatact atggtgcaag ttgtcacaca aacgaaaact
     7921 gtgaaaggaa ctatcattga tgaaagcggg gagccgctga ttggagtttc tatcgttgtg
     7981 aaaggaacaa gtacaggtac gattaccgat tttaacggta acttctctat cgatcttccg
     8041 gcgggaagaa aagaactggt catttcttat atcggttaca aagaacaaac ggtgacagtg
     8101 acaggcaacg gaccggtcaa tgtgaaaatg gtttcggaca cacaggcatt ggatgaagtg
     8161 gttgttgtgg gttacggtac gatgaaaaaa cgcgatttga caggagctat cacttctgta
     8221 aaaagtgaag atgtagtgat gaatccaagt tcaaatccga tgcaggcttt acaaggtaag
     8281 gtggcaggat tggatattac gcgtgaatcg ggacaggccg gttcgggagt aaagatgcag
     8341 ttgcgtggta accggtcatt ccagaaggat tccggaaatc ctttatttat aattgatggt
     8401 atgccggggg attattctac attgaatccg aatgatattg aaagcattga agttttaaaa
     8461 gatgcttctt cgacagctat ttatggttca agtggtgcga acggtgttat tttaattact
     8521 actaaaggtg gtaaggaagg taaagcaatt gttaatttta atgcatacgt aggtgtaaac
     8581 ggctggtcaa ggactccgga gatgcgtagt ggagaaagtt atatacaaac cttgagagat
     8641 gcatctgttg gtgctggcga tggacgttgg agttcggttg ctgatgataa aaatctgttt
     8701 actactgatg ctgaatggaa tgcacatcaa aatggccaat atatagattg ggtggatgct
     8761 ttgttgaaaa ccagtgtaac acagaattat tctgtttctg tggctggtgg aacggaaaag
     8821 acaaaggcat atttttctct gaacttctct aatgaggatg ggcagtttgc acaagatagc
     8881 tataaacttt attcatctaa aatccgggta gatcataaga ttaaaaagtg gatgaaggtg
     8941 ggcattgatg ctcaactgtc ttatgtacat caaaataaag ctgattctga tttacagact
     9001 ttgatggcgt caaatcctct tggatcgttg tataatgaag atggaagcat caatccgcaa
     9061 cctgttgccg atccttcatc tacagtatat aattatcttt taaatgagga taaaagtttg
     9121 taccgcaatc aggctcaaaa ccttaaggtc tattttaatc cttacttgga aatcactcct
     9181 cttaaagggc tgacttttat tactcgtgct ggtgctagtt tgggatattc acgtagtaac
     9241 actttcacag gagaggggtc tgttcaatgg tataaggcaa atcaaacggc agacggcatt
     9301 aaggcgcaag ttaaggacaa ccgttcgtat aattataagt gggaaaatat acttacttac
     9361 aatttccaga ttaagaaagt gcatgatata actcttactg cagttacatc ttggaatcac
     9421 aatcgtagcg atgtcactac tttgtatcaa aaaggtgttt ctgataataa attcttatgg
     9481 cataatattc ttgatggtaa ttccgcaact tcgggaagta cttcttatag tatgtctaag
     9541 gggatgggat atgtcggccg tttgaactat tcatatatgg gtaggtattt atttgctgca
     9601 tctgtccgcc atgacggctc ttccagactg gcagaaggta ataaatggga tactttcccg
     9661 gctttctctt tgggatggag aatttctgat gaaaaattta tggagagtac gactaactgg
     9721 ttgagtaatc tgaaaattcg cttcggatat ggtgttacgg gtagtacagc gggtattgat
     9781 ccgtattcgt ctgctgcatc attggatgct actgctgtaa atatgatatt aggaggtgtt
     9841 ctgacaccga tttataaatt ctcacagaat attccgaact atttgcttac atgggaaaag
     9901 tcgtataaca cgaatattgg tattgacgct gcattcttaa ataatcgcat tgatgtcagt
     9961 atggaatatt ataatacaaa aacaaaagat gttatatgga acaaggcact tcctgttatt
    10021 aatggagcat tctccccgga tggcggacct aaagcgaatt atactactaa tttaaatatg
    10081 tgtgagacta gcaataaagg ttttgagttg gctcttaata cacgtaatat tataacaaag
    10141 aactttactt ggagttcaag tgtaactttc aatcataata aagagaaaat aaccaaattg
    10201 tccggtggag attcagatgt gcttaataat ggtgacaccg gttatgcatt ggcattggga
    10261 gaagctatta actcttatta
//
