LOCUS       gnlProkkaMNJPIAAD_17   14206 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MNJPIAAD_17.
ACCESSION   gnlProkkaMNJPIAAD_17
VERSION     gnlProkkaMNJPIAAD_17
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 08:12:32
            Original ID  :: gnl|Prokka|MNJPIAAD_17
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14206
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14206
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1515:4206]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1516..4206
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..14206
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14206
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             complement(408..638)
                     /locus_tag="ctg17_1"
                     /transl_table=11
                     /translation="METTVMNVAVSQGIWAVLAVFLLIYIVKSNEQRDTKQEEREKNYQ
                     TVIESLTEKFQILNQVQSDLKEIKDNLFNKN"
     CDS             939..1463
                     /locus_tag="ctg17_2"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIAQKLKLSRQYVNRMKK
                     KLILRYISENK"
     CDS             complement(1516..4206)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     762.8; E-value: 9.3e-231)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_3"
                     /sec_met_domain="DUF4135 (E-value: 2.5e-93, bitscore:
                     304.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.6e-52, bitscore:
                     169.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKLDYLCRKNRTMFLKILILDVHRQKNFGNLKGSTPKEQYDYYE
                     KKYLNNATYVKSLLQEYPELKRLLELKNNSIQRAECEIRKSLYAEKEQIQKIFCDGRKF
                     SGTVGIYMSKGDTHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGISC
                     RTVQYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAHG
                     EYPVIIDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNSR
                     VLISAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYTE
                     CIIRGFCRAYMVAMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSREC
                     RKALLNVIHKEGESSFMKGIHDYEIESLLEMDIPCFEIDANSRSVYDGNGGEHKEYLPC
                     TPYESWRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIYS
                     QIRKIVHRICSRAIIREQSAGWAGLQFWDNGHWNLRSGGIYLYDGISGIVLFLAKYLHD
                     FEEKNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLTG
                     KRVWMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVVAVMLYKETGNLKYYEIAADMEK
                     DLWKKGQETGNGYGWRLKGTDGPLAGMSHGNSGFMMAYAMLYECDHKVEYADKIQLLLR
                     YEDSLYSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLNA
                     ADSLFYGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAKI
                     SGTEYLNLAFMNGISGTGMALMEIL"
     CDS             complement(4200..4328)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_4"
                     /transl_table=11
                     /translation="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYGTIVCC"
     CDS_motif       complement(4218..4328)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /locus_tag="ctg17_4_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4200..4217)
                     /prepeptide="core"
                     /locus_tag="ctg17_4_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="519.7"
                     /monoisotopic_mass="519.2"
                     /core_sequence="TIVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /leader_location="[4217:4328](-)"
     CDS             complement(4345..5826)
                     /locus_tag="ctg17_5"
                     /transl_table=11
                     /translation="MLKVLLYGLATFMETGIGVWIFSQTFSERRILEKKYYVLEWLLYS
                     LIFFGIYNFSVSLWQIDKKIEKYVIKVICIYIIGLIAGIIYDIFFVKKKEMVLRRILYI
                     GMIFWLTAQYWAGYQSLLMIILGSGIIVLYVFCYFDCTFKQAYVWNFFYAVNIGLIKEA
                     YVVYAGVFNHKQWDDFYSYPRGHTYQEVIFWILGCLFIFWIIKFILSVNSIKGILRTRL
                     RELFIIGLLEYVLLIVSIIYKFGTIKKENFVMTACLLAVSNIALIGVYVKFQKKTLEMR
                     NQILDMRCKLMEEEYEELRMSYDRYRCLVHDEKHLLLYIKECLENGELDSCITFLNHYK
                     RESIRYSGVAWTGIPEINFMLNIKVRKMEEKNIFFKVDSKIEKIPMKDIDFVVLLGNLL
                     DNAIEAAEKCEDGKGKITCIFRNINDMFIFKVKNTSIYKPYEKNTKFYTSKKEKDEHGW
                     GIESVKQIVRKYNGEIDFKYDKDFFEVEIIISDNT"
     CDS             complement(5830..6537)
                     /locus_tag="ctg17_6"
                     /transl_table=11
                     /translation="MIRIMILDDDEMYLKKEKDITEQYFAEKNVDCTVTIYQNVEWFLL
                     GLNEEKFDMYILDIRMPGENGIEAAREIRRLYPDPVIIFITNFVDYAIEAYEVNTYRYI
                     PKECLKEKLPQAYDALLPGIMEKEERYYIINKRNEVEKLAYSDIFYMKKEGKYVIFVHR
                     RGEVKIRASLSTIEKELNSKEFIISDRGYLANIQHVMKMKGRDLYMRDGNIITVGRERF
                     KGVREAILNYWGV"
     CDS             complement(6543..7097)
                     /locus_tag="ctg17_7"
                     /transl_table=11
                     /translation="MDEYTKDLYTMMFSLQTLQNQGITIRETVYKSLDKLLLWNKESEN
                     SKYLELALLHMQAYANMGFALDEENKTIREILKKTGKTREDFFPKGYLLGKRIKLTKSQ
                     VRGMIGRWRPSRDSPMTIGELVDDIIRKVKNHEEGRYIYQYHRTDVTTKGDIEVYELVI
                     NKDESYFYDVKKFRFYTFMEE"
     CDS             7216..7551
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 59.6; E-value: 8.2e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg17_8"
                     /transl_table=11
                     /translation="MKNNTIGKRIAEARINRNITQEHLEELSGLSISTISRIETGKYMP
                     TIENLLKLSEILDVGLDYFLYDLLPHNKDIQSPAIQDAISIMNQMGERQTEYIVKILKI
                     YQASHQD"
     CDS             7739..8626
                     /locus_tag="ctg17_9"
                     /transl_table=11
                     /translation="MTKTEKAVTWAIEIANDPAHGYDQDNRWGPDYDCSSLVISAWQQA
                     GVPVKTKGATYTGNMKSVFLSCGFKDVTSKVNLSTGSGMKRGDVLLNIASHTVMHIGNG
                     QVVSASKNENNGYHGGKPGDQSGKEIKLQNYYNFPWDCVLRYTEDSSTTDPEPQPTTGN
                     AKIRKGQSYANKFANAGISITGKRDAATKKAGIKVLQTALNRDYGAGLDVDGIWGTNTS
                     DALGKHYVKSGETQYMVTAAEILLLLRAYDPNGVEIPGTFGSGLLSAVKAFQKAQGLTV
                     SGTCDRNTFLKLIS"
     CDS             complement(8769..9527)
                     /locus_tag="ctg17_10"
                     /transl_table=11
                     /translation="MKQKKIVIIMAGILAAAAAMTGCAEQNKTATQVDYTQNSQGKSEQ
                     TKQKTAEKSQPDKKQVNKSTFDGKENSNQTADKKTKVFASSNNAGDVQNSGNGTDGTAG
                     TDTDDSQTTGVDTSTSEDNGSTGNDGTQSDQRADQAMIYDSEGNGRLISEADDGNWYDS
                     DGNYYGSWEDIEDAMVNENGVTDQDGNKYYWTAPHDASEEVTDPYDLYSWDPGTNSYIP
                     FQAAESDCSPIGRGNGWYYYDEDSGEYVPW"
     CDS             complement(9809..12490)
                     /locus_tag="ctg17_11"
                     /transl_table=11
                     /translation="MKSNYKIFTAVFLSAIMTAAAPLTVCGAEVFSAGESFSDGTGSIP
                     AILTDMVLPDGEIGTEYQVQLEADTDVNWSLEEGSELPAGFTLSSGGVISGMPQEEGSF
                     SFTVQADNGIGVSSQELSLYVAQREQEPVIKQYELTSGTALIDLGIHAEGEQSRKRLFL
                     YNAGTDSLHLSDFPQSRYFDFSYAPIFDTNTDEEMQPGSCAAVDIDDKKDLPAGNYEET
                     VTFETKEGASCKVTLKVIVGASSEKDYELSIETGTEEEFTESDFYDPEFRVEKYVVVRN
                     SGKKETRIRVDTSGLKNFEVDDQMAKWTEDYEEQDSKKLLKPGETLYFYILPKQEYGIY
                     DETFAFLADDGSRYPLHVTMNREKNPTEKKQLEITEKSAGGFPTMQWGYKTLPEAKTYI
                     LKNVTDTDMKLSFNRSKECSVLLSGNAYLAPGESTELRLWPKLGLSVGKYSFQVTVTAK
                     TVAGEHLTTQNLYNSFIVGDRTYQGLADAVEPVTGITNGAEKTADALHLPDWLEVYGAE
                     VDGKKTTFSASVKWDVEDCVYDPKSKAAQSFTVTGHLELNEDENNEGLDTAVQIMVQVD
                     AYQTLNRPVIDLLRTGVRTNYAMLYLRDLSNEADGYQFVTAKSQKDLKKGNYTAQTKIT
                     NSELNQYPELKYIPEGTHSLYCRAYKENSSHVMEYGEWSDGVPVTVKVKTPDAPVVQKV
                     QVKKNDVRIVLNSKGEEPDGYDVVAARSKNGKEPSDYIKVKSGYSGSSKELILRGVPAG
                     TWYIGVHAYKYLNGSNTKVLSKWAEVRKVTVKTSLVTGKPAVKSTKVSRQGTKRNVTVT
                     FTAPKSCDGTDWVLAKKVSKSDDGSYTGVSSYAYTKKNQTKTTVVFKSVKPGVYYLAGR
                     AYVKGYAKSYTKWSKIKKIVVK"
     CDS             complement(12685..13653)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 217.2; E-value: 6.3e-66)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_12"
                     /transl_table=11
                     /translation="MKLGILGAGGIASTMAKTVAGMKGVEAYAVAARDLERAREFAQKY
                     EVKKAYGSYEEMLADDEVGLVYIATPHSHHYLHAKMCLEAGKHVLCEKAFTVNAEQAQK
                     LFDLAKEKKLLITEAIWTRYMPSRKMINDIIESGVIGEVTAVTANLSYTVSHVERIRKP
                     ELAGGALLDVGVYPINFASMVLGDKVKDVKATAIFQNGVDILDSIAMVFEGDRMATLQC
                     GAREISDRMGSIFGTRGYMQVQNINNPEKITVFDTEHKEVASYVVPEQISGYEYEVESC
                     MKAIHEGKTECPEMPHAETIRIMKIMDDIRKSWNYEIPCIE"
     CDS             complement(13784..13972)
                     /locus_tag="ctg17_13"
                     /transl_table=11
                     /translation="MDKEKEIKAYLDGELLPEVRMKYEIAEEMGLLDRVLSDGWKSLSA
                     KETGRIGGLMTKRKKRN"
ORIGIN
        1 cgggcttttt taaaatttta ttttcgttag ggctactcat ttttggaagt taaggagaaa
       61 taaaaaaatt ttggcaaaag caaaaaagta gaaaaaacac catgaaaaaa tgacaaaaca
      121 gagaagccgc aatccagcat aaacacttgg attgcggcct tttttttaat ctattttaca
      181 ctacccaaaa gtcaggtttt attatcataa tataccattt actatacgaa catctgtaaa
      241 tctgggatta aaagtattct aatggacacg aatgttatgc ttatattcat ctaccatttt
      301 agtaaacata tttttctcaa attaacctat tttcttacct aaaatgacag aagccctctc
      361 cgctggaaaa atatatcctg cagaaaaggc ttttttcttt tccctattta atttttgtta
      421 aaaagattat ccttaatctc tttcagatcg ctttgaacct gattcagaat ctgaaatttc
      481 tcagttaaac tctcaatcac cgtctggtaa tttttctctc gttcttcctg ctttgtatcc
      541 ctctgttcat ttgatttcac aatgtaaatc agaagaaaaa ccgcaagcac agcccagatt
      601 ccctgtgaaa ctgccacatt cataaccgtt gtttccatgg tttctgcctc cttccttaat
      661 cttcttttat tatgcaaact ttttctatgt tttgtctact aaaagtcttt tctaatctta
      721 ttattaccgt tttaatttaa agcatatttc tattctctac aattattttg caaatctctt
      781 tttaccatgt atttcttctc ctatcgctga tctaaatttg caacctcact taataaagag
      841 ttttttctct tccatttgta aactcacaaa tttttttctt ttttagtttc tgatcagcag
      901 ttttcttact acttccccta aaaaggaggt agatacctat gaaaacactg acagaactta
      961 tccaaaatta tcaaaatggt atcccagatt cagacagtga aattctcaaa cgtatggaac
     1021 cgcttgtgaa aggatatgca tcccggattc actgcatgga acgcgaagat tccacacagg
     1081 aattgtatct tactctgtta aagacattgc catatttaag ttcttcatcc tcagaaggtg
     1141 aatgtatcag atacatgcag acctctgtcg aaaacagata tcgttccctt tgccgcagtt
     1201 gtctttccga acctgaaaaa gatgattttg attcttgttc tgtttcatta caggctcccg
     1261 acagttttga tgacacctat tatgatgtaa ccgcatatat caactcttac ccttcggaca
     1321 gtgtccagag aaaaattctg tccatgtact tttatcagga taaaagcgat gcccagattg
     1381 ctcagaaact gaagctgtcc cgccagtacg tcaatcggat gaagaagaaa ctaattctca
     1441 gatatatttc cgaaaacaaa taaaagaaac acctgctgac cataaattta cagtctgcag
     1501 gtgttccctt agttttcata aaatttccat taatgccatt cccgtaccgg aaatgccatt
     1561 cataaaagcc agattcagat attctgtccc agatattttt gccgggtgat ccagttgaaa
     1621 taaaaggcag tcacataacg cctcatattg ctccttcatt tttttgttac catattttcg
     1681 aagatacttc ttcataataa gtaaattccc ggacatccca tgacacagac aaattttttc
     1741 atcctgttct ccataaaaca aagagtctgc agcatttaac ctgtcttttt taatctgcat
     1801 atcctcagga aacagctcct ccagtttcat tcgtgaaagc aggattcccg gcgccccatg
     1861 gcaccatgca ttcatgaagc tttcccctga actctctcgt aaatccttcc agtttccggc
     1921 tttctctgag tacagagaat cctcatatct cagcaaaagc tgtattttat cagcatattc
     1981 cactttatga tcacattcat acaacattgc ataagccatc ataaatccac tgttgccatg
     2041 agacattcca gccagcggtc cgtctgttcc ttttaatctc catccgtatc catttccggt
     2101 ttcctgtcct ttcttccaca aatctttttc catatctgcc gctatttcat aatatttcag
     2161 atttccggtt tctttatata acatcactgc cactacaata gctccggcat ttccgctcag
     2221 ataatccagt tgtgaatctt ctttccatac cctctcaata atgctgaaat gcttttccgc
     2281 ataaatcatc cacactcttt ttcctgtaag tttaaacaga taaagatagg tatataccac
     2341 cgagctttct ccatttacaa tacctgtcag aagattttta tcataaatct gttttttgtg
     2401 tatttcatct gtataagctt tcaatctcaa aacagcaaga tgataaattt cttctgcact
     2461 tgcattcttt tcttcaaaat catgaagata ttttgcaaga aacaagacta tcccggatat
     2521 tccatcatat aaatatattc cacctgatct gagattccag tgaccattat cccagaattg
     2581 cagacccgcc cagccagcgc tctgttcccg gataattgct ctgctgcaga ttcgatgaac
     2641 tatctttctg atctgactgt atattttgcg ctctttatct gtgtcatatc cctttatcct
     2701 ggtcggaaac atctttttct ttccatcaga tgccttcagc atttccatgg acagcctgat
     2761 ataatcacac tgacattcca tatcagagta actcatctgc ttcatatgca ttcgccatga
     2821 ctcataagga gtacagggca gatattcttt atgttctccg ccatttccat cataaacaga
     2881 tctgctgttc gcatcaatct caaagcaggg tatatccatt tccagaagac tctcaatttc
     2941 ataatcatga atccccttca taaaagaaga ttccccctct ttgtgaatca cattcaaaag
     3001 agctttcctg cattctcttg acttcatata atccggatga aacgaagcca taagatacat
     3061 tgcatactgt tgggtatgcc gcagtacaac tctggaacgt ccgtcaaaaa agccggacaa
     3121 catcacctcc actttcttat ctgccattgc caccatgtac gctctgcaaa atcctctgat
     3181 aatgcattcc gtataatctg ccgcattgat aacctgatca tttagtctta caatgcattc
     3241 ctttatctgc atttccacag gttcatattc tatgtgaata tcagatgttt tatcatcctt
     3301 taccacagga agtttaaacg gcgtttttat cttttcctct gttcccattg cacttataag
     3361 aactctgctg tttcctctgc cccatgtgag aacagggagc attcctgtat gtataaccga
     3421 atttgccaat tttatttctg tacttttgtt tattttttct tctacactac ttccgtcttt
     3481 ttctgattgt tgttttaaat atcccggata cgtttccata tcgataatca caggatattc
     3541 tccatgtgcg ataatatttt caccatgaag atctgttgct ccaagggcat atcccaaaaa
     3601 cagatgtatg cccattctga aataataatg ctccacctcg ctttcgtttt tacagggaat
     3661 attctcaatt ttttcttccc atccatagga atcatgagat aaatattgta ccgtcctgca
     3721 ggaaattcct gtttttctgc ataaatagtt ataaagttcc tgatatttta tattcttatc
     3781 aagactatgt ggcttatagt acagaattgt tccattatcc aattctacct ttgccacact
     3841 tcgtcctcct ctgtgtgtat cgcctttcga catgtaaatt cccacagtcc cggaaaactt
     3901 tcttccatca cagaatattt tttgtatctg ttctttttct gcataaagag atttcctgat
     3961 ttcacattct gctctctgga tagagttatt ttttaattca agcagacgtt ttaactcggg
     4021 atattcctgc agtaaagatt ttacatatgt tgcattgtta agatattttt tttcataata
     4081 atcatattgt tcttttggcg tacttccttt tagatttcca aaatttttct gccgatgtac
     4141 atctaagatt aatattttaa gaaacatagt tcgatttttt ctgcataaat aatccaattt
     4201 cagcaacaca ctatagttcc atatacaata aaagacaatt tctcttctat actttccgta
     4261 tctattatct ctatttcatc taattctttt tccacatttc ctattatttt atcattcatt
     4321 tcgttcataa ccgtcactct cccattatgt attatcgcta attattattt ctacttcaaa
     4381 aaaatcttta tcatatttaa aatctatttc accattatac tttcttacaa tttgtttgac
     4441 actttcaatc ccccatccgt gctcatcttt ctctttttta cttgtataaa atttagtgtt
     4501 tttttcataa ggtttatata tgcttgtatt ctttacttta aaaataaaca tatcattaat
     4561 atttcgaaaa atacacgtaa ttttaccttt tccatcttca cacttttcag cagcttctat
     4621 tgcattatcc aaaagatttc ctaggagtac aacaaaatct atgtctttca tcggaatttt
     4681 ttctattttt gaatctactt taaaaaaaat attcttttct tccatttttc gcacttttat
     4741 attcaacata aaatttattt ctggaattcc tgtccacgct actccactat atctaatgct
     4801 ttctctcttg taatgattca aaaaagtgat acatgaatcc agttctccat tttccaggca
     4861 ttcttttata tataaaagca aatgtttttc atcgtgcacc aaacaccgat accggtcata
     4921 tgacattctc aattcttcat attcttcttc cattaatttg catctcatat ctaaaatctg
     4981 atttctcatt tctagggtct ttttttgaaa cttaacatat acaccaatca atgctatatt
     5041 actaactgct aataaacatg cggtcattac aaaattttcc tttttaatcg taccaaattt
     5101 gtatatgatg ctaactatta ataaaacata ctctaacaat ccaataataa aaagttccct
     5161 cagacgtgta cgcaatattc cttttatact gtttactgac aaaataaatt taattatcca
     5221 aaatatgaat aaacagccta aaatccaaaa tataacttcc tgatatgtat gtcctctcgg
     5281 atatgaataa aaatcatccc actgtttatg gttaaacacc cctgcatata caacataagc
     5341 ctcttttatc aatcctatat taactgcata gaaaaaattc caaacatatg cctgtttaaa
     5401 tgtgcaatca aagtagcaaa aaacatataa tacaattatt ccactcccaa gaataatcat
     5461 taacaacgat tgatatccag cccaatactg agcggttaac caaaatatca tgccgatata
     5521 taatattctt cttaagacca tctccttttt ctttacaaaa aaaatatcat atataattcc
     5581 tgcaattaat ccaattatgt atatacaaat aacttttatg acatattttt ctattttttt
     5641 atcaatctgc cataatgaaa cagaaaaatt ataaattcca aaaaaaatca aagaatacaa
     5701 cagccattct agaacataat attttttttc taatattctt cgttcagaaa acgtctggct
     5761 aaatatccag acacctatcc ctgtctccat aaacgttgcc agtccataca ataaaacttt
     5821 aagcattctt catacccccc agtaattcag aattgcttct ctgacacctt tgaatctttc
     5881 tctgccaact gtaataatat taccgtcccg catataaaga tcccttcctt tcatcttcat
     5941 cacatgttgg atgtttgcaa gatatcctct gtcagatata ataaattctt ttgaattcag
     6001 ttctttttct attgttgaca gacttgctct gatctttact tccccacgcc tgtgcacaaa
     6061 aatgacatat tttccttctt ttttcatata gaaaatatca gaatatgcca gtttttcaac
     6121 ttcatttctt ttatttatga tatagtaccg ctcttctttc tccataattc caggaagaag
     6181 cgcatcataa gcctgcggaa gtttttcctt cagacactct ttggggatat aacgataggt
     6241 gtttacctca tatgcttcta ttgcataatc cacaaaattt gtaataaata taataaccgg
     6301 atccggataa agtctgcgaa tttccctcgc tgcctctatt ccgttttctc caggcatccg
     6361 gatatccaga atatacatat cgaatttttc ttcattcaat cccagcagaa accattccac
     6421 attctggtat atcgttaccg tgcaatctac gtttttctct gcaaaatact gttctgtgat
     6481 atccttttct tttttcagat acatttcgtc atcatccaga atcattattc ttatcatagc
     6541 aattattcct ccatgaatgt ataaaatctg aatttcttca catcataaaa ataactttca
     6601 tccttattga tgaccagctc ataaacctcg atatcccctt tggttgtcac atcagttctg
     6661 tgatactgat aaatgtatct gccttcctca tggtttttta cctttctgat gatatcatcc
     6721 accagttctc cgattgtcat cggactgtct ctggaaggtc tccatcttcc aatcatacca
     6781 cgaacctgtg acttggtcag tttaattctc tttccaagaa gatatccttt cgggaaaaag
     6841 tcttctctgg tctttcctgt cttttttaat atctcacgta ttgtcttatt ttcttcatct
     6901 aaagcaaatc ccatattagc ataagcctgc atatgaagca acgctaattc gagatattta
     6961 ctgttttcag attctttatt ccataacagt aatttgtcca gacttttata tacagtttct
     7021 ctgattgtaa ttccctgatt ttgcaaagtc tgcaaagaaa acatcatggt atacaaatcc
     7081 tttgtatatt cgtccatatt cctatattcc tcctgtcata aaacatatca aatttgatta
     7141 gtcgcttgtc atttatatcc ttatacatat ttaattccgt ctgttaaact ttatcaaagg
     7201 aaaggatttt tatttatgaa aaacaatact attggaaaaa gaattgcaga agctcggatc
     7261 aacagaaata ttacccagga acacctggaa gaattaagtg gtttatctat aagtacgatc
     7321 agccggattg aaacaggtaa gtatatgcct actattgaaa atctccttaa gctttctgaa
     7381 attcttgatg tgggacttga ctattttctt tatgatctgc ttcctcataa taaagatatt
     7441 caaagcccgg ctattcagga tgcgatttca atcatgaatc aaatgggtga acgccagact
     7501 gaatacattg taaaaatact gaaaatatac caggcctctc atcaggatta aatataatta
     7561 caattcgaca attttcgtgt ttttgtcctc gaaaagcatt tttctgacct cgaagcaaca
     7621 atcaggaaat gctttttatt tttttctgtt tcatgtttac atttttccct tttctcactc
     7681 tttataagat gtatcaccgg tgagcaaata aataatcaaa tttcaggagg ataaaaaaat
     7741 gacaaaaaca gaaaaagcag taacatgggc aattgaaatc gcaaacgatc cggcacacgg
     7801 atatgatcag gataacagat ggggaccgga ctacgattgt tcttcactgg taatctccgc
     7861 atggcagcag gctggtgtac ctgtaaaaac aaaaggagcc acttatacag gaaatatgaa
     7921 atccgtcttt ctgtcctgcg gctttaagga tgtgacttcc aaagttaatc tcagcacagg
     7981 aagtggcatg aaacgtggtg acgtattatt aaacatcgca agtcatacag taatgcacat
     8041 tggcaatggt caggtggtat ctgccagcaa aaatgaaaat aatggatatc atggtggtaa
     8101 acccggagat cagagtggaa aagagatcaa acttcagaat tattacaatt tcccttggga
     8161 ttgtgttctc cgttatactg aagattcttc aactactgat cctgagccac agccaactac
     8221 tggaaatgca aaaatccgca aaggtcagag ttatgccaat aaattcgcaa atgccggaat
     8281 ttccattacc ggaaaaagag acgctgctac taaaaaagca gggattaaag ttcttcagac
     8341 agctctgaac agggattatg gtgccggtct ggatgtagac ggtatctggg gaaccaacac
     8401 aagcgacgct cttggtaaac attacgtaaa aagcggtgaa actcagtata tggtaactgc
     8461 cgccgagatt ctccttcttt tacgtgctta tgatccaaac ggtgtagaaa ttcccggtac
     8521 ctttggctca ggacttctct ctgctgtaaa ggcattccag aaggcacaag gcttaacggt
     8581 ttccggaacc tgtgacagaa acactttcct gaaactgatc agctgatttt taccagataa
     8641 acatccggca gaattctttt cactgattct gccggatatg ccccttcact atttcttgta
     8701 tataaaaaga aacagttttg aaacccatca aaatgatttc aaaactgttt cttttgtttt
     8761 cttatttttt accacggaac atattcgccg ctgtcttcat cataataata ccagccgttt
     8821 cctctgccta taggactaca gtcagattcc gcagcctgaa acggtatata ggaattggtt
     8881 cccggatccc aggaatacag gtcatacgga tctgtgacct cttctgatgc atcgtgaggt
     8941 gctgtccagt aatatttatt gccatcctga tctgtgacac cattttcatt taccatagca
     9001 tcttcaatat cttcccagct tccatagtaa tttccgtcac tgtcatacca gtttccatca
     9061 tcagcttcag aaatcagtct tccatttccc tcactgtcat atatcattgc ctgatctgcc
     9121 ctctggtcag attgagtacc atcattacct gttgaaccat tatcttcaga tgtagaagtg
     9181 tccacccctg tggtctggga atcatctgta tcagttcccg cagtaccgtc tgttccattc
     9241 cctgaattct gtacatcgcc cgcattattg gatgaggcaa atactttcgt cttcttatcc
     9301 gcagtctgat ttgaattttc ttttccatcg aatgtacttt tatttacctg ttttttatcc
     9361 ggctgagatt tttctgctgt tttttgtttt gtctgttcgg atttcccctg tgagttctgc
     9421 gtataatcaa cctgtgtcgc tgttttattc tgttccgcgc agcccgtcat agcagccgct
     9481 gctgctaaaa tccctgccat aataattaca atctttttct gcttcatttt gttgtccttt
     9541 ctacatttac taaaaatgtc attgccttta tcataatgtg cttttcctgt tcattattac
     9601 atactccaca ggcttcgatg cctcatatgt cccttatctg tcataaaaag gacattattt
     9661 atctccaaat tcagacaaga tttgagtata ataagtggca gtaccgtaaa ctttgagtat
     9721 tacaggaaaa agcaggtata aacgcctggt aaaaggggga tttttcttct taaaagtgaa
     9781 atctctgtga aacaaatgac agcagtgctt atttcacaac tattttcttt attttcgacc
     9841 atttcgtata actttttgca tagcctttta cataggcacg tcctgcaagg tagtagactc
     9901 cgggcttcac acttttaaag accaccgtgg tttttgtctg atttttcttt gtataagcat
     9961 aactgcttac acctgtatag ctgccgtcat cagatttgga aactttcttt gccagtaccc
    10021 agtctgttcc atcacaggac tttggagcag taaacgtcac cgttacattt ctttttgttc
    10081 cctgtctgga aaccttagtt gatttaacag caggttttcc tgttacaagg cttgttttta
    10141 cagttacctt cctgacctct gcccatttac tgagcacttt ggtattgctc ccattcagat
    10201 atttataagc atgtacgcca atataccacg ttcctgccgg tacgccccgt aagataagct
    10261 ctttactgct tccggaatac ccactcttta cctttatata atccgatggt tcttttccgt
    10321 tcttacttct ggcagcaaca acatcgtaac cgtccggttc ctcacccttg ctgttaagta
    10381 ctattctgac atcatttttc ttcacctgca ccttctgaac cacaggtgcg tccggagtct
    10441 ttacctttac cgtaaccgga accccgtctg accattcccc atattccata acatggctgc
    10501 tgttctcttt gtatgccctg caataaagac tatgtgttcc ctccggaata tacttcagct
    10561 caggatattg attcagttca gaatttgtaa tttttgtctg cgcagtataa ttcccctttt
    10621 tcagatcctt ctgagatttg gctgtcacaa actgatagcc gtctgcttca ttggaaagat
    10681 ctctcagata aagcattgca taatttgttc tcactccggt tctcaataag tcaataaccg
    10741 gtctgtttaa tgtctgatat gcatccacct gtaccattat ctgtacggca gtgtccagtc
    10801 cttcattatt ttcatcttca ttcagttcca gatgaccggt cactgtaaaa ctttgagctg
    10861 ccttgctttt cggatcatac acacaatcct ccacatccca cttcacagat gcagaaaatg
    10921 ttgttttctt tccatccacc tcggcaccat aaacttccag ccaatctggc agatgcaaag
    10981 catcagctgt tttttctgca ccattggtaa ttccggtcac aggctcaaca gcatctgcca
    11041 gtccctgata agtccggtct cctacaataa aagaattata cagattctgc gttgtcaggt
    11101 gttctcctgc cactgttttc gcagtcacag tcacctgaaa actatatttt cccaccgaaa
    11161 gccccagttt gggccagagt ctcagttctg tgctctcccc aggtgccaga taagcatttc
    11221 cagataataa cacactacat tctttactac ggttaaaaga cagcttcata tctgtatcag
    11281 taacattttt cagaatatat gtctttgctt ccggaagtgt cttatagccc cactgcattg
    11341 tcggaaaacc cccggcagac ttttcagtaa tttccagctg cttcttttct gtcggattct
    11401 tctctctgtt cattgtaaca tgaagaggat atctgcttcc gtcatctgcg agaaatgcaa
    11461 acgtttcatc ataaattccg tattcctgct tcggcaatat ataaaaataa agcgtttctc
    11521 ccggtttcag cagctttttg gaatcctgtt cctcataatc ttctgtccac tttgccatct
    11581 ggtcatctac ttcaaagttc ttaagaccgg aagtgtctac ccgtattctg gtttcctttt
    11641 tccctgaatt tctgactact acatacttct ccacacgaaa ttccggatca tagaaatcgc
    11701 tttctgtaaa ctcttcttct gtacctgttt ctatactcag ctcataatct ttttcagagg
    11761 aagctcccac aattactttc agagtaacct tacaggaagc accttctttt gtctcaaatg
    11821 tcactgtctc ttcataattt ccggcaggca gatccttctt atcatcaatg tccacagccg
    11881 cacaacttcc gggctgcatt tcttcatccg tatttgtatc gaaaatcggt gcgtaggaaa
    11941 aatcaaaata tctgctctgc ggaaaatcag agagatgaag cgagtctgtt cctgcattat
    12001 aaagaaataa ccgcttacgt gactgttctc cctctgcatg aattcccaga tcgatcaaag
    12061 cagtacctga tgtcagctca tactgcttta taacaggttc ctgctcacgc tgtgcaacat
    12121 aaaggctcag ttcctgtgaa gaaactccaa taccattgtc cgcctgtaca gtaaagctga
    12181 aactcccttc ctcctgtggc attccactga tcactccccc ggaagacaac gtaaatcccg
    12241 ccggaagctc acttccctct tccagactcc agttcacatc tgtatcagct tcaagctgta
    12301 cctgatattc cgttccaatc tctccatccg gcagaaccat atctgtcaat atggcaggaa
    12361 tactccccgt tccatcactg aaagattctc ccgccgaaaa aacttccgcc ccacatactg
    12421 ttaacggagc tgctgctgtc ataattgccg ataaaaaaac tgctgtaaaa attttgtaat
    12481 tacttttcat tcttctcctc cagataataa aatataaaag tatcaattta cctaattaat
    12541 attaatatac cactggacgg gaatgtttct gtaattacgg aatgacatgt tgtataatgg
    12601 tcatgaatat cagaaaagcc agtaatgttt cgggtatatg tcaaaaacat tactggtctt
    12661 ttttataaga ttattccaca ctttttattc gatacaggga atctcataat tccaggattt
    12721 acggatgtcg tccatgattt tcatgatcct tattgtttcc gcatgaggca tttccggaca
    12781 ctccgttttt ccctcatgaa ttgctttcat gcaggattct acctcatatt catatcctga
    12841 gatctgttcc ggcacaacat aagaagccac ttctttatgt tcggtatcaa acactgtaat
    12901 cttttccgga ttattgatat tctgcacctg catatatcct ctggttccga aaatacttcc
    12961 cattctgtct gagatttctc ttgctccaca ctgaagggtt gccatgcggt ctccctcaaa
    13021 caccatggca atgctgtcca gaatatccac tccattctga aagattgcag tagcctttac
    13081 atcctttacc ttatcgccaa gcaccatgga ggcaaaattg atcggatata cgcctacatc
    13141 cagaagagca cctcctgcaa gctccggttt acggatacgt tccacatgac ttactgtata
    13201 gctgagattc gcggtaactg ccgtaacttc tccgatcaca ccactttcaa taatatcgtt
    13261 gatcatcttt ctggacggca tatatcttgt ccagattgct tctgtgatca gaagcttttt
    13321 ctcttttgca aggtcaaata atttttgtgc ctgctctgca tttacagtaa atgccttttc
    13381 acaaagcaca tgctttcccg cttccagaca cattttcgca tgcagataat ggtgtgaatg
    13441 aggagttgcg atataaacca gtccaacctc atcatctgcc agcatttcct cataggatcc
    13501 atatgctttt tttacttcat atttctgtgc aaattcccgg gcacgttcca gatcacgggc
    13561 agcaaccgca tacgcctcca cacctttcat tcctgccact gttttcgcca tagtagaagc
    13621 aatgcctcct gctcccagaa tacctaactt cattttattg tcctcccata tttatagcag
    13681 ataaaattat ccacttcgct acttgctcta attttacagc atcatcgccc ggagaacaag
    13741 tttattccgt tatatgttta tcccatatca ttcatttatt ttttcagttt ctcttttttc
    13801 gttttgtcat caaccctcca atccttccag tctctttcgc agacagactt ttccatccat
    13861 cactcaatac tctgtccagc agtcccattt cctctgcaat ttcatacttc attctgacct
    13921 ccggcaataa ttctccatca agataagctt ttatttcctt ctctttatcc aaaacagccc
    13981 acactccttt tctttggagt atgggctgtt ttcttaattt ttatactgta tttcattcaa
    14041 acggatattc gcaatccgct tcgctgcctg cctgattcgg ttaaacttct gtctattaca
    14101 gattggatcc tgagattctg ttatcttttc ggaataataa ttgcagcaat aatatatgcc
    14161 cagattcccg caccgccaaa gcaggtaagg atcacccatg ccagac
//
