LOCUS       gnlProkkaBODIBGDG_35   15708 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BODIBGDG_35.
ACCESSION   gnlProkkaBODIBGDG_35
VERSION     gnlProkkaBODIBGDG_35
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 05:19:15
            Original ID  :: gnl|Prokka|BODIBGDG_35
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15708
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15708
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3017:5708]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3018..5708
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..15708
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15708
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             127..681
                     /locus_tag="ctg35_1"
                     /transl_table=11
                     /translation="MDEYTKDLYTMMFSLQTLQNQGITIRETVYKSLDKLLLWNKESEN
                     SKYLELALLHMQAYANMGFALDEENKTIREILKKTGKTREDFFPKGYLLGKRIKLTKSQ
                     VRGMIGRWRPSRDSPMTIGELVDDIIRKVKNHEEGRYIYQYHRTDVTTKGDIEVYELVI
                     NKDESYFYDVKKFRFYTFMEE"
     CDS             687..1394
                     /locus_tag="ctg35_2"
                     /transl_table=11
                     /translation="MIRIMILDDDEMYLKKEKDITEQYFAEKNVDCTVTIYQNVEWFLL
                     GLNEEKFDMYLLDIRMPGENGIEAAREIRRLYPDPVIIFITNFVDYAIEAYEVNTYRYI
                     PKECLKEKLPQAYDALLPGIMEKEERYYIINKRNEVEKLAYSDIFYMKKEGKYVIFVHR
                     RGEVKIRASLSTVEKELNSKEFIISDRGYLANIQHVMKMKGRDLYMRDGNIITVGRERF
                     KGVREAILNYWGV"
     CDS             1398..2879
                     /locus_tag="ctg35_3"
                     /transl_table=11
                     /translation="MLKVLLYGLATFMETGIGVWIFSQTFSERRILEKKYYVLEWLLYS
                     LIFFGIYNFSVSLWQIDKKIEKYVIKVICIYIIGLIAGIIYDIFFVKKKEMVLRRILYI
                     GMIFWLTAQYWAGYQSLLMIILGSGIIVLYVFCYFDCTFKQAYVWNFFYAVNIGLIKEA
                     YVVYAGVFNHKQWDDFYSYPRGHTYQEVIFWILGCLFIFWIIKFILSVNSIKGILRTRL
                     KELFIIGLLEYVLLIVSIIYKFGTIKKENFVMTACLLAVSNIALIGVYVKFQKKTLEMR
                     NQILDMRCKLMEEEYEELRMSYDRYRCLVHDEKHLLLYIKECLENGELDSCITFLNHYK
                     RESIRYSGVAWTGIPEINFMLNIKVRKMEEKNIFFKVDSKIEKIPMKDIDFVVLLGNLL
                     DNAIEAAEKCEEGKGKITCIFRNINDMFIFKVKNTSIYKPYEKNTKFYTSKKEKDEHGW
                     GIESVKQIVRKYNGEIDFKYDKDFFEVEIIISDNT"
     CDS             2896..3024
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_4"
                     /transl_table=11
                     /translation="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYGTIVCC"
     CDS_motif       2896..3006
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /locus_tag="ctg35_4_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3007..3024
                     /prepeptide="core"
                     /locus_tag="ctg35_4_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="519.7"
                     /monoisotopic_mass="519.2"
                     /core_sequence="TIVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /leader_location="[2895:3006](+)"
     CDS             3018..5708
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     763.2; E-value: 7.2e-231)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_5"
                     /sec_met_domain="DUF4135 (E-value: 1.4e-93, bitscore:
                     304.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.1e-52, bitscore:
                     168.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKLDYLCRKNRTMFLKILILDVHRQKNFGNLKGSTPKEQYDYYE
                     KKYLNNATYVKSLLQEYPELKRLLELKNNSIQRAECEIRKSLYAEKEQIQKIFCDGRKF
                     SGTVGIYMSKGDIHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGISC
                     RTVQYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAHG
                     EYPVIIDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNRG
                     VLISAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYTE
                     CIIRGFCRAYMVAMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSREC
                     RKALLNVIHKEGESSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLPC
                     TPYESWRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIYS
                     QIRKIVHRICSRAIIREQSAGWAGLQFWDNGHWNLRSGGIYLYDGISGIVLFLAKYLHD
                     FEEKNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLTG
                     KRVWMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVVAVMLYKETGNLKYYEIAADMEK
                     DLWKKGQETGNGYGWRLKGTDGPLAGMSHGNSGFLMAYAALYECNHKAEYADKIQLLLR
                     YEDSLYSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLNA
                     ADSLFYGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAKI
                     SGTEYLNLAFMNGISGTGMALMEIL"
     CDS             complement(5761..6285)
                     /locus_tag="ctg35_6"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIARKLKLSRQYVNRMKK
                     KLILRYISENK"
     CDS             6586..6816
                     /locus_tag="ctg35_7"
                     /transl_table=11
                     /translation="METTVMNVAVSQGIWAVLAVFLLIYIVKSNEQRDTKQEEREKNYQ
                     TVIESLTEKFQILNQVQSDLKEIKDNLFNKN"
     CDS             complement(7055..7291)
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MEVKVIMMPYLSCKKIENDVYNFPTWQYCKYKDIFDSRIIINSTA
                     KFYISISYQKDLLSIDTRIFTPSHKHLDCGHFF"
     CDS             7419..9128
                     /locus_tag="ctg35_9"
                     /transl_table=11
                     /translation="MYLKSRVKLPDVHGKLTRLRRGDITYIKYEYDRYYDPEKKYTYPQ
                     RATIGKVCPDDDTMMIPNEAFLKYFPDAVLSGMEDRTERSSCLRVGTYAVMHKIVLDYS
                     LDKLLGQFFSERDMALLLDLASYSIVEESNVAQHYPDYAYNHPLYSSGMKIYSDASVSD
                     FFKSITKDKSTGFLNEWNAKRNRRERIYISYDSTNKNCQAGEIELAEFGHAKTDIGSAI
                     INYSVGYDLKNKEPLFYEAYPGSINDVSQLRTMLGKITGYGYKKIGFILDRGYFSRGNI
                     RYLDECGYSFVIMAKGMSSFISDLILENKGTFENKRSCDMNAYGVYGKTVQRTLFEGDE
                     KKRYIHIYHSISKDADEREHFENALRERTALLMSHQNETVEFGSAYEKYFYLHYDKDGV
                     FLYPEEKTTVTEREISLCGYFVIITSERMTAKEALHLYKSRDVSEKLFASDKSFLGNKS
                     MRSHTNEGVEGRIFTQFIALIIRNKIYTALQEENEKLEKKQNYMTVPAAIRELEKIEMT
                     RQTDNVYRLDHAVTAKQKKILEAFGMNEGNITYRAGEISNTLKKSNIQKERR"
     CDS             9131..9358
                     /locus_tag="ctg35_10"
                     /transl_table=11
                     /translation="MAREINAELLDTKIEKAQKNLVKAKHRYDAAAATLKDLLDKRDAL
                     RQKKLLDAIAQSGRSYEEIMQYLHSKSEEA"
     CDS             9312..9641
                     /locus_tag="ctg35_11"
                     /transl_table=11
                     /translation="MKKSCSTCTVNLKRRDQMLTEYYFAVRYGDIIILLYHEDMMSVWE
                     LLFKNSQKEKALKRFLEYCYMIDVKVAFEGLKGEKTKGLKATLKFAKEHDMCMTEAQIQ
                     GANNM"
     CDS             9878..11053
                     /locus_tag="ctg35_12"
                     /transl_table=11
                     /translation="MKSKKVKKILLIALTCVAISASVSAEAAMKSQITIESKNKYEQLK
                     ISESRVYGEYPTGDYKKIMLLPSVSKVEKFCFEDNLNIEEVEWMASVDTVPVFAFSTCP
                     KLKRVILSDNVKKIGQSAFIYCGELTSVKLPQNLQSIDFFAFADCRKLKTLYIPETVTE
                     IGAEAFINCDSLTVHGKKNSYAYYYCKMNGIPFVSEGTASKPETNRPYIKSVDSDIVNK
                     QIYVTIDLSGKVKNADGYQYQIYDGTKVLANKNSANTTCILKKVPTMGFARVRSYTVQN
                     GKKSYSRWSNEMRMPPVKLNKDNIKLIKITGKKKTVTAQFGNLKYSDGFDCVLKNADSG
                     ENIVLKNQKKNTVTFKNIKPGVYYLKAHAYTLLNGIKQFGVWSDNKKVVVK"
     CDS             complement(11134..12846)
                     /locus_tag="ctg35_13"
                     /transl_table=11
                     /translation="MPGTFNGTTLTISATPVDGALIPDKSATNVAGIAIVGSDMYCVKT
                     TGLKTTLLKTTDYMATKATAVKKDLNWFALGLTKIGNYLYMLAEDHKGYGGSTTIVKLD
                     TKGNQLGTYSINEICPKGALGITAADGTNEKFIIMHYADKSNAGTLAFSVVDWKAAEAA
                     STFTVTNSGFGYTTRLQDIYYHTSFGLFILTNNTFSTLQNRILVVDYHLTDDKGKKYTP
                     CSVINVNKTGEYKQYNLESICMKANHLVLASNVITSDGTAEDKFSVLEGITYSGKTYTF
                     ACGFKAGARVPTKVDPNYETTNLGCVSFNGNNTPYFIKQSQDKVAVLGYCKNYMNTSAG
                     VSHFKTFTDGLLGHANGMSCFNGKFFVVAGNNKVVAISSNKEDEEITYTVTSNDNDKSF
                     ALKAINYFYEANTALLLSVVDGTLKLYKCTFENEKNVKATYLCTLVNAGQPTSQDIFYH
                     NKLGLFVGTSNPHTVSGVTTKITTKNTLLHYNLKKLDDSKLLYPDFGFVTDIPAKDAQG
                     RTYNSFELESVALDQNNKLIAVCNVNVKDATHTSGLASTDGFFQYNTLEFITA"
     CDS             13368..14090
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 213.5; E-value:
                     5.4e-65)"
                     /gene_kind="transport"
                     /locus_tag="ctg35_14"
                     /transl_table=11
                     /translation="MRMSEMTDAYVKLDKVSKIYGTKEVKIVAVDEISFEIAKGEFVVI
                     VGPSGAGKTTVLNILGGMDQATSGEVLVDGRNIARYNSRQLTGYRRNDIGFVFQFYNLV
                     PNLTALENVELALQICKNPLDAREVLEEVGLKDRLTNFPAQLSGGEQQRVSIARALAKN
                     PKLLLCDEPTGALDYQTGKAILKLLQDMCRERGMTVIVITHNSALTPMADRVIKIKNGK
                     VSRMTMNDHPTPIEEIEW"
ORIGIN
        1 tttttcataa ataaaaatcc tttcctttga taaagtttaa cagacggaat taaatatgta
       61 taaggatata aatgacaagc gactaatcaa atttgatatg ttttatgaca ggaggaatat
      121 aggaatatgg acgaatatac aaaggatttg tataccatga tgttttcttt gcagactttg
      181 caaaatcagg gaattacaat cagagaaact gtatataaaa gtctggacaa attactgtta
      241 tggaataaag aatctgaaaa cagtaaatat ctcgaattag cgttgcttca tatgcaggct
      301 tatgctaata tgggatttgc tttagatgaa gaaaataaga caatacgtga gatattaaaa
      361 aagacaggaa agaccagaga agactttttc ccgaaaggat atcttcttgg aaagagaatt
      421 aaactgacca agtcacaggt tcgtggtatg attggaagat ggagaccttc cagagacagt
      481 ccgatgacaa tcggagaact ggtggatgat atcatcagaa aggtaaaaaa ccatgaggaa
      541 ggcagataca tttatcagta tcacagaact gatgtgacaa ccaaagggga tatcgaggtt
      601 tatgagctgg tcatcaataa ggatgaaagt tatttttatg atgtgaagaa attcagattt
      661 tatacattca tggaggaata attgctatga taagaataat gattctggat gatgacgaaa
      721 tgtatctgaa aaaagaaaag gatatcacag aacagtattt tgcagagaaa aacgtagatt
      781 gcacggtaac gatataccag aatgtggaat ggtttctgct gggattgaat gaagaaaaat
      841 tcgatatgta tcttctggat atccggatgc ctggagaaaa cggaatagag gcagcgaggg
      901 aaattcgcag actttatccg gatccggtta ttatatttat tacaaatttt gtggattatg
      961 caatagaagc atatgaggta aacacctatc gttatatccc caaagagtgt ctgaaggaaa
     1021 aacttccgca ggcttatgat gcgcttcttc ctggaattat ggagaaagaa gagcggtact
     1081 atatcataaa taaaagaaat gaagttgaaa aactggcata ttctgatatt ttctatatga
     1141 aaaaagaagg aaaatatgtc atttttgtgc acaggcgtgg ggaagtaaag atcagagcaa
     1201 gtctgtcaac agtagaaaag gaactgaatt caaaagaatt tattatatct gacagaggat
     1261 atcttgcaaa catccaacat gtgatgaaga tgaaaggaag ggatctttat atgcgggacg
     1321 gtaatattat tacagttggc agagaaagat tcaaaggtgt cagagaagca attctgaatt
     1381 actggggggt atgaagaatg ctgaaagttt tattgtatgg actggcaacg tttatggaga
     1441 cagggatagg tgtctggata tttagccaga cgttttctga acgaagaata ttagaaaaaa
     1501 aatattatgt tctagaatgg ctgttgtatt ctttgatttt ttttggaatt tataattttt
     1561 ctgtttcatt atggcagatt gataaaaaaa tagaaaaata tgtcataaaa gttatttgta
     1621 tatacataat tggattaatt gcaggaatta tatatgatat tttttttgta aagaaaaagg
     1681 agatggtctt aagaagaata ttatatatcg gcatgatatt ttggttaact gctcagtatt
     1741 gggctggata tcaatcgttg ttaatgatta ttcttgggag tggaataatt gtattatatg
     1801 ttttttgcta ctttgattgc acatttaaac aggcatatgt ttggaatttt ttctatgcag
     1861 ttaatatagg attgataaaa gaggcttatg ttgtatatgc aggggtgttt aaccataaac
     1921 agtgggatga tttttattca tatccgagag gacatacata tcaggaagtt atattttgga
     1981 ttttaggctg tttattcata ttttggataa ttaaatttat tttgtcagta aacagtataa
     2041 aaggaatatt gcgtacacgt ctgaaggaac tttttattat tggattgtta gagtatgttt
     2101 tattaatagt tagcatcata tacaaatttg gtacgattaa aaaggaaaat tttgtaatga
     2161 ccgcatgttt attagcagtt agtaatatag cattgattgg tgtatatgtt aagtttcaaa
     2221 aaaagaccct agaaatgaga aatcagattt tagatatgag atgcaaatta atggaagaag
     2281 aatatgaaga attgagaatg tcatatgacc ggtatcggtg tttggtgcac gatgaaaaac
     2341 atttgctttt atatataaaa gaatgcctgg aaaatggaga actggattca tgtatcactt
     2401 ttttgaatca ttacaagaga gaaagcatta gatatagtgg agtagcgtgg acaggaattc
     2461 cagaaataaa ttttatgttg aatataaaag tgcgaaaaat ggaagaaaag aatatttttt
     2521 ttaaagtaga ttcaaaaata gaaaaaattc cgatgaaaga catagatttt gttgtactcc
     2581 taggaaatct tttggataat gcaatagaag ctgctgaaaa gtgtgaagag ggaaaaggta
     2641 aaattacgtg tatttttcga aatattaatg atatgtttat ttttaaagta aagaatacaa
     2701 gcatatataa accttatgaa aaaaacacta aattttatac aagtaaaaaa gagaaagatg
     2761 agcacggatg ggggattgaa agtgtcaaac aaattgtaag aaagtataat ggtgaaatag
     2821 attttaaata tgataaagat ttttttgaag tagaaataat aattagcgat aatacataat
     2881 gggagagtga cggttatgaa cgaaatgaat gataaaataa taggaaatgt ggaaaaagaa
     2941 ttagatgaaa tagagataat agatacggaa agtatagaag agaaattgtc ttttattgta
     3001 tatggaacta tagtgtgttg ctgaaattgg attatttatg cagaaaaaat cgaactatgt
     3061 ttcttaaaat attaatctta gatgtacatc ggcagaaaaa ttttggaaat ctaaaaggaa
     3121 gtacgccaaa agaacaatat gattattatg aaaaaaaata tcttaacaat gcaacatatg
     3181 taaaatcttt actgcaggaa tatcccgagt taaaacgtct gcttgaattg aaaaataact
     3241 ctatccagag agcagaatgt gaaatcagga aatctcttta tgcagaaaaa gaacagatac
     3301 aaaaaatatt ctgtgatgga agaaagtttt ccgggactgt gggaatttac atgtcgaaag
     3361 gcgatataca cagaggagga cgaagtgtgg cgaaggtaga attggataat ggaacaattc
     3421 tgtactataa gccacatagt cttgataaga atataaaata tcaggaactt tataactatt
     3481 tatgcagaaa aacaggaatt tcctgcagga cggtacaata tttatctcat gattcctatg
     3541 gatgggaaga aaaaattgag aatattccct gtaaaaacga aagtgaggtg gagcattatt
     3601 atttcagaat gggcatacat ctgtttttgg gatatgccct cggagcaaca gatcttcatg
     3661 gtgaaaatat tattgcacat ggagaatatc ctgtgattat cgatatggag acatatccgg
     3721 gatatttaaa acaacaatca gagaaagacg gaagtagtgt agaagaaaaa ataaacaaaa
     3781 gtacagagat aaaattggca aattcggtta tacatacagg aatgcttcct gttctcacat
     3841 ggggcagagg aaacagagga gttcttataa gtgcaatggg aacagaggaa aagataaaaa
     3901 caccgtttaa acttcctgtg gtaaaggatg ataaaacatc tgatatccac atagaatatg
     3961 aacctgtgga aatgcagata aaggaatgca ttgtaagact aaatgatcag gttatcaatg
     4021 cggcagatta tacggaatgc attatcagag gattttgcag agcgtacatg gtggcaatgg
     4081 cagataagaa agtggaggtg atgttgtccg gcttttttga cggacgttcc agagttgtac
     4141 tgcggcatac ccaacagtat gcaatgtatc ttatggcttc gtttcatccg gattatatga
     4201 agtcaagaga atgcaggaaa gctcttttga atgtgattca caaagagggg gaatcttctt
     4261 ttatgaaaga gattcatgat tatgaaattg acagccttct ggaaatggat ataccctgct
     4321 ttgagattga tgcgaacagc agatctgttt atgatggaaa tggcggagaa cataaagaat
     4381 atctgccctg tactccttat gagtcatggc gaatgcatat gaagcagatg agttactctg
     4441 atatggaatg tcagtgtgat tatatcaggc tgtccatgga aatgctgaag gcatctgatg
     4501 gaaagaaaaa gatgtttccg accaggataa agggatatga cacagataaa gagcgcaaaa
     4561 tatacagtca gatcagaaag atagttcatc gaatctgcag cagagcaatt atccgggaac
     4621 agagcgccgg ctgggcgggt ctgcaattct gggataatgg tcactggaat ctcagatcag
     4681 gtggaatata tttatatgat ggaatatccg ggatagtctt gtttcttgca aaatatcttc
     4741 atgattttga agaaaagaat gcaagtgcag aagaaattta tcatcttgct gttttgagat
     4801 tgaaagctta tacagatgaa atacacaaaa aacagattta tgataaaaat cttctgacag
     4861 gtattgtaaa tggagaaagc tcggtggtat atacctatct ttatctgttt aaacttacag
     4921 gaaaaagagt gtggatgatt tatgcggaaa agcatttcag cattattgag agggtatgga
     4981 aagaagattc acaactggat tatctgagcg gaaatgccgg agctattgta gtggcagtga
     5041 tgttatataa agaaaccgga aatctgaaat attatgaaat agcggcagat atggaaaaag
     5101 atttgtggaa gaaaggacag gaaaccggaa atggatacgg atggagatta aaaggaacag
     5161 acggaccgct ggctggaatg tctcatggca acagtggatt tctgatggct tatgcagcgt
     5221 tgtatgaatg taatcataaa gcggaatatg ctgataaaat acagcttttg ctgagatatg
     5281 aggattctct gtactcagag aaagccggaa actggaagga tttacgagag agttcagggg
     5341 aaagcttcat gaatgcatgg tgccatgggg cgccgggaat cctgctttca cgaatgaaac
     5401 tggaagagct gtttcctgag gatatgcaga ttaaaaaaga caggttaaat gctgcagact
     5461 ctttgtttta tggagaacag gatgaaaaaa tttgtctgtg tcatgggatg tccgggaatt
     5521 tacttattat gaagaagtac cttcgaaaat atggtaataa aaaaatgaag gagcaatatg
     5581 aggcgttatg tgactgcctt ttatttcaac tggatcaccc ggcaaaaata tctgggacag
     5641 aatatctgaa tctggctttt atgaatggca tttccggtac gggaatggca ttaatggaaa
     5701 ttttatgaaa actaagggaa cacctgcaga ctgtaaattt atggtcagca ggtgtttctt
     5761 ttatttgttt tcggaaatat atctgagaat tagtttcttc ttcatccgat tgacgtactg
     5821 gcgggacagc ttcagtttcc gggcaatctg ggcatcgctt ttatcctgat aaaagtacat
     5881 ggacagaatt tttctctgga cactgtccga agggtaagag ttgatatatg cggttacatc
     5941 ataataggtg tcatcaaaac tgtcgggagc ctgtaatgaa acagaacaag aatcaaaatc
     6001 atctttttca ggttcggaaa gacaactgcg gcaaagggaa cgatatctgt tttcgacaga
     6061 ggtctgcatg tatctgatac attcaccttc tgaggatgaa gaacttaaat atggcaatgt
     6121 ctttaacaaa gtaagataca attcctgtgt ggaatcttcg cgttccatgc agtgaatccg
     6181 ggatgcatat cctttcacaa gcggttccat acgtttgaga atttcactgt ctgaatctgg
     6241 gataccattt tgataatttt ggataagttc tgtcagtgtt ttcataggta tctacctcct
     6301 ttttagggga agtagtaaga aaactgctga tcagaaacta aaaaagaaaa aaatttgtga
     6361 gtttacaaat ggaagagaaa aaactcttta ttaagtgagg ttgcaaattt agatcagcga
     6421 taggagaaga aatacatggt aaaaagagat ttgcaaaata attgtagaga atagaaatat
     6481 gctttaaatt aaaacggtaa taataagatt agaaaagact tttagtagac aaaacataga
     6541 aaaagtttgc ataataaaag aagattaagg aaggaggcag aaaccatgga aacaacggtt
     6601 atgaatgtgg cagtttcaca gggaatctgg gctgtgcttg cggtttttct tctgatttac
     6661 attgtgaaat caaatgaaca gagggataca aagcaggaag aacgagagaa aaattaccag
     6721 acggtgattg agagtttaac tgagaaattt cagattctga atcaggttca aagcgatctg
     6781 aaagagatta aggataatct ttttaacaaa aattaaatag ggaaaagaaa aaagcctttt
     6841 ctgcaggata tatttttcca gcggagaggg cttctgtcat tttaggtaag aaaataggtt
     6901 aatttgagaa aaatatgttt actaaaatgg tagatgaata taagcataac attcgtgtcc
     6961 attagaatac ttttaatccc agatttacag atgttcgtat agtaaatggt atattatgat
     7021 aataaaacct gacttttggg tagtgtaaaa tagattaaaa aaaatggccg caatccaagt
     7081 gtttatgcga gggtgtaaaa attcttgtgt ctatggaaag taaatctttc tgataagaaa
     7141 tagatatgta aaattttgct gtcgaattaa tgattatgcg gctgtcgaat atatctttgt
     7201 acttacagta ttgccatgta ggaaaattat atacatcatt ttcgattttt ttgcatgaca
     7261 agtaaggcat catgattacc ttaacttcca aaaatgagta gccctaacga aaataaaatt
     7321 ttaaaaaagc ccgtatttct gcggaaatta ttgcaaaaat acgggttgtg ctgtacaata
     7381 aatttagggc tatataaacc tgaataaagg aggcaaatat gtacctgaaa tcaagagtta
     7441 agctaccgga tgtgcatgga aaattgaccc gattaagacg cggggatatc acatatatta
     7501 agtatgagta tgatcgctat tatgatccgg agaaaaaata tacctatcca cagagagcga
     7561 ctataggcaa ggtatgtcca gatgatgaca ctatgatgat tcctaacgaa gcctttctga
     7621 aatactttcc agatgcagtc ttatcaggga tggaagaccg gacagaacgt agcagctgtc
     7681 tgcgggttgg tacatatgct gtaatgcata aaatagtatt ggattattcg ttagacaagc
     7741 tgctcggaca gttcttctct gagcgggata tggcattatt gcttgacctt gcctcttact
     7801 ctattgtaga agaaagcaat gtggcacagc attatccgga ttacgcatac aatcatccac
     7861 tgtatagttc tggtatgaag atctatagtg atgcgtcggt aagtgatttc tttaagagca
     7921 tcaccaagga taagagtaca ggctttctga atgaatggaa tgcaaagaga aatcgaaggg
     7981 agcgtattta tatttcctat gattctacga ataagaactg tcaggccgga gagattgaac
     8041 tggctgaatt cggtcatgcc aagacagata tcggttcagc tatcatcaac tattcggttg
     8101 gatatgatct taagaataaa gaaccactct tttatgaagc ctatcctgga agtattaacg
     8161 acgtatcaca gcttaggacc atgcttggta aaatcactgg gtatggctat aaaaaaatcg
     8221 gtttcatttt ggacagggga tatttcagcc gtggaaatat acgctattta gacgaatgtg
     8281 gttatagttt tgtgatcatg gctaaaggca tgtcttcttt cataagtgat ttgatcttag
     8341 agaacaaagg aacgttcgaa aataagcgct cttgtgacat gaatgcctat ggtgtgtatg
     8401 gaaaaacagt acaaaggact ttatttgaag gcgatgaaaa aaagagatac attcatattt
     8461 atcatagtat ttcaaaagat gctgatgaac gggagcattt tgaaaacgca ctgagagagc
     8521 ggacagcttt gctgatgtca catcagaatg aaacagtaga gttcggttca gcttacgaaa
     8581 aatactttta tcttcactac gataaagatg gcgtgttttt atatccggaa gaaaaaacaa
     8641 ctgtgacaga acgggaaata tcattatgcg gatactttgt tattattaca tccgaaagga
     8701 tgaccgcaaa ggaagcactg catctttata agagccgtga tgtatctgag aaactttttg
     8761 cctctgataa atcattcctt ggaaacaaga gcatgcgttc acatacaaac gaaggagttg
     8821 agggaaggat ttttacacaa ttcatcgcac tgataatccg aaacaaaatt tatactgcat
     8881 tacaggaaga gaacgaaaaa cttgagaaga aacagaatta tatgacagtt ccggcagcaa
     8941 tcagggaact tgagaagatt gaaatgacac gccagacgga taatgtatac cggctggacc
     9001 atgctgtaac agcaaagcag aaaaaaatct tagaggcttt tgggatgaat gaaggaaaca
     9061 ttacttatcg agccggagag atcagtaata cacttaagaa atcaaacatt cagaaagaaa
     9121 ggcggtaaat atggcacgtg aaataaacgc agaactactg gacactaaaa ttgaaaaagc
     9181 acagaagaat ctggtgaaag caaagcatcg gtatgatgct gcggcagcaa cattaaaaga
     9241 tttattggat aagagggatg cacttcgcca gaaaaagtta ttggatgcta tagcacagag
     9301 tggacggagc tatgaagaaa tcatgcagta cctgcacagt aaatctgaag aggcgtgatc
     9361 aaatgttaac ggaatactat tttgcagtca ggtatggaga tatcattatt cttctctatc
     9421 atgaagatat gatgtctgta tgggaattat tatttaagaa cagccagaag gaaaaggcat
     9481 tgaaaagatt tttagaatac tgctacatga tagatgtaaa agtagcattc gaaggtttga
     9541 aaggagaaaa aaccaaaggg ttaaaggcaa ctcttaaatt tgcgaaagaa catgatatgt
     9601 gtatgactga agcacagatt caaggtgcca ataacatgta aatttccagc ccgagatgct
     9661 tttagggcta ttccaggctg gaaattaagg cagctgctaa acaaaaggct ttcagactac
     9721 aggcgaacat atgttgctgc aaaactgtgg agattaattt aaatttgcat tttggttcgg
     9781 ggtcattaga atacttttaa taccagaaat acaggatctt ttatagttag tgatatatta
     9841 tgataataga tgaatattat tgattggagg agattctatg aagtcaaaga aagtaaagaa
     9901 aatattgttg attgctttaa cgtgtgtagc aatttctgca tctgtctcag cagaagctgc
     9961 tatgaaatca cagataacca ttgaaagtaa aaataagtat gaacagttga aaatttcaga
    10021 gagccgtgtg tatggagaat acccaactgg agattataag aagataatgc ttcttccttc
    10081 ggtttctaaa gtagaaaaat tttgttttga agataatttg aacatagaag aagtagagtg
    10141 gatggcttca gtagatactg ttccagtttt tgcctttagc acatgtccaa agcttaaaag
    10201 ggtaatactt tctgataatg tgaaaaaaat tggacaaagt gcatttatat actgcggtga
    10261 actgacgagt gttaaacttc cccaaaatct tcaaagtata gatttttttg catttgctga
    10321 ctgtcgaaaa ctgaaaacgt tatatatacc tgaaacagtt actgagatag gtgctgaggc
    10381 gttcataaat tgtgattctc taacagttca tggaaagaaa aattcatatg catactatta
    10441 ctgtaagatg aatggtattc cttttgtaag tgagggaact gcttcaaaac cagaaacaaa
    10501 tcgtccgtat ataaaatctg ttgattcaga tatagtaaac aaacaaatct atgttacaat
    10561 tgatttgagc ggaaaagtaa agaatgcaga tggatatcaa tatcaaatat atgatggtac
    10621 taaggtatta gctaataaaa attctgcaaa cacaacctgt atattaaaaa aagtgccgac
    10681 tatgggattt gccagagtcc gttcttatac tgttcaaaat ggtaaaaaaa gttatagcag
    10741 gtggtctaat gaaatgcgta tgcctcctgt taaactaaat aaagataata taaaattaat
    10801 aaaaattacc gggaaaaaga aaacagtaac cgcacagttt ggaaatttaa aatacagtga
    10861 tgggtttgat tgcgtactta agaatgcaga ttcaggagaa aatattgtat taaaaaatca
    10921 aaagaaaaat acagttactt ttaaaaatat aaaaccggga gtttactatt tgaaagcgca
    10981 tgcatatacg ttgttgaatg gtattaaaca gtttggcgta tggtcagata ataaaaaagt
    11041 tgttgttaaa tagaaaattg gaattataaa aagcaggcga aaaactgcct gctttttata
    11101 atggaaattt atgctgttat tgatgtagcg aaatcaagct gtaataaatt caagcgtatt
    11161 atactgaaag aagccgtcag tggatgctaa accactggtg tgggtagcat ctttgacatt
    11221 gacattgcac acagcgatta atttattatt ttgatccaga gccactgatt ccagttcaaa
    11281 actgttatat gtgcggccct gagcatcttt agcaggaata tctgtaacaa atccgaaatc
    11341 cggatataaa agtttgctat catcaagttt tttcagatta taatgaagca aggtgttttt
    11401 tgttgtgatt ttagtcgtta ctccacttac agtatgtgga ttactggttc cgacaaaaag
    11461 ccctaattta ttgtgataga aaatatcctg ggatgtaggc tgaccggcgt ttaccagtgt
    11521 acaaagataa gtggctttta catttttttc attttcaaat gtacatttat agagctttaa
    11581 tgttccgtca acaacggaca ataataaagc tgtatttgcc tcataaaaat aattaattgc
    11641 tttaagagca aatgatttat cgttatcgtt ggaagttact gtatatgtta tttcctcatc
    11701 ctctttgtta ctgctgatag caaccacttt gttatttcct gcgacaacaa agaattttcc
    11761 gttaaaacag ctcataccgt tggcatgacc taataaaccg tcagtgaatg ttttaaagtg
    11821 agatacacct gcgcttgtat tcatataatt tttacagtag ccaagaacag cgactttatc
    11881 ttgactttgt tttataaaat atggagtatt gtttccgtta aaggatacac atcccagatt
    11941 agttgtttca tagttgggat ctactttggt aggtacacgg gctcctgctt taaaaccgca
    12001 tgcaaaagta taggttttac cggagtaggt aatgccttcc agcacagaga atttatcttc
    12061 tgcggttcca tcagatgtta taacattgga tgcaagcaca aggtgattgg ctttcataca
    12121 gattgattca aggttgtact gcttatattc acctgtttta tttacattga tgaccgaaca
    12181 tggagtgtat tttttacctt tatcatcagt aagatgataa tcaactacca gaatacggtt
    12241 ctgaagtgtt gaaaaagtgt tatttgtcag gataaataat ccaaatgaag tgtgatagta
    12301 aatatcctga agccgtgtgg tataaccaaa acctgagtta gtaactgtga atgtacttgc
    12361 tgcttcagca gccttccagt ctacaacact gaaagctaat gtcccagcat tgctcttgtc
    12421 agcgtaatgc ataatgataa atttctcgtt agttccgtca gcagcagtga tacctaatgc
    12481 gccttttgga caaatttcat tgatactgta cgtaccgagc tgattgcctt tggtatccag
    12541 ttttacgatg gttgtagaac cgccgtaacc tttatggtct tctgcaagca tatacagata
    12601 atttccaatt ttggtaagtc ccagagcgaa ccagttcaga tcttttttta cggcagttgc
    12661 ttttgttgcc atgtagtcag tcgttttgag taatgtagtt ttaagaccgg ttgtctttac
    12721 gcaatacata tctgacccca caatggcaat tcccgctaca tttgttgcac ttttatcggg
    12781 aatcagtgca ccgtctacgg gggtagctga aatagttaaa gttgttccgt taaatgttcc
    12841 tggcataatt tttgcctcct ttaaattttt tgaatttgca aattcactat ataaagatgc
    12901 tgctttttgt gatttgtaaa ccataagtgt gtatatgagc atgatttttt tcttttatgc
    12961 ggaaatcagg taagaataaa aataaagatt cgaggtcaga tgatgtatgt ttagtcccac
    13021 ttttatattt tcgtcatcag cttaatgtaa aataataacg ggtaaagaag atataagatg
    13081 ttctggtaca tacaattaag aagaaagggg catgtgctgt gtatagtcaa aatgatgaac
    13141 cgcctgagat gatcaggcgg ttttgaagta tctggatttt ttatgaatat tttattttta
    13201 attacaggta taatgtgtta caataaatat aaccattaag actaccaggc aggtcagaat
    13261 ttgacctgcc tgtaaataaa tacggaaata aatcggggtc aaaagaatcg ttaataattg
    13321 taacaaaata aaattaccgg tgtagcaaaa ataaaattac aggggaaatg cggatgagtg
    13381 agatgacaga tgcatatgta aaactggata aggtttccaa gatatatgga accaaagaag
    13441 taaagatcgt tgcagtggat gagatcagct ttgagattgc caagggagag ttcgtagtga
    13501 tcgttggtcc cagcggtgcg ggcaagacga cagtgctgaa cattcttggg ggtatggatc
    13561 aggctaccag cggagaagtt ctggtggatg gaaggaatat tgccagatat aacagcaggc
    13621 agcttaccgg ttatcggaga aatgatattg gatttgtatt ccagttctat aatctggtgc
    13681 ctaatcttac agcgctggag aacgtagaac tggcattgca gatctgtaaa aatccgctgg
    13741 atgccaggga ggttctggag gaagtgggac tgaaggacag actgaccaat ttcccggcac
    13801 agctttccgg tggtgagcag cagagagttt ccattgccag ggcactggcg aagaatccca
    13861 agctcttact gtgtgatgag cccacaggtg cactggacta ccagactggt aaggcaatct
    13921 taaagctttt gcaggatatg tgcagggagc gtggaatgac agtgatcgtc attacccata
    13981 actcggcgct gacacctatg gcagaccgtg tgatcaagat caagaacggc aaggtttcca
    14041 ggatgacgat gaatgaccat cctacaccca tagaggagat tgaatggtag gtgatgaata
    14101 tgaaagcaat gcataaagat ttctggatgg agatacgaaa aagtaaggcc aggtttattt
    14161 ccatatttat gatcgttgct ctgggagttg cattcttttc cggaatacag gcgtcgtcac
    14221 cggatatgcg cttctcgggt gatgcctatt atgatgaaac caatcttatg gatatcaaag
    14281 taatgggaac tctgggactg acggaggatg atgtagctgc cattaagaag gtggacggag
    14341 tagagaatgc agagggcgcc tatggtacag atgtaatgtg tggagaaggc gagaagcaga
    14401 aggtacttca tgtggaagct gtggatcaaa ccatgaaccg gatctcagtg acagagggaa
    14461 aagctccgga aaaaagcgga gagattttcc ttgactgtat ttttgctgag agcaatggat
    14521 ataaggtggg tgatcagatt accctgaaag agggcggaga cagcgaactg ctgaaaaaga
    14581 cagattacac agttgtaggt ttaggagaga gtcctctcta catatcctat aatcgcggaa
    14641 attccacttt gggttccggt gaggttaatg gatttgccta tgtgctccct gaggattttg
    14701 accaggaggt ttatacacag atctatgtgc aggctcatgg ggcacaggat ctgatcagct
    14761 atacagatgc ttatgattcc ctgatagagc gagtgcagga gcgagtggag gggattgagg
    14821 cagaacggtg tcaggtcaga tatgatgaga ttgtagagga agccaatgac aagcttgcag
    14881 atgccagaca ggaacttgaa gacggaaaga aggaagctaa tgagaagctt gcggatgcca
    14941 gacaggaact ggaggacggc aaaaagaagt taaaagacgg caagaaggaa tataaggatg
    15001 gcaagaaaaa gcttgcagac gcaaaaaagg aactggagga cggaaaagcc cggcttgcag
    15061 atgcaaagaa ggagttagag gacggcagat cccagcttgc cagtgcgaaa gagcagcttg
    15121 ccagtggcag agcacagatc gcatctgcaa aggaacagct gaatgccgga tgggcggagg
    15181 tttccgaaaa ccaggcaaag cttgatgatg gaaaggctca gcttgaggat ggcaagaacc
    15241 agttaagtgc cggtgagaag aagattgcag atgcaaagac gcagcttacc cagagtcagc
    15301 aggagcttga caatggcaag gcgcagatcc agtcaggcag agagcagatt gcagcaacca
    15361 gacaggactt aaatgccaaa aaggaaagct gcaatcaggg acttgcgcag attgagcagc
    15421 aggaggccgg acttgcagaa ggagaggctc agcttgaggg tgccagaagt cagcttgcag
    15481 cattgcaggc acagtatgag caggcacaag cttcgggcac atattccgag gaagacctgg
    15541 cggctctggc agcacaggtt tccgcttatc aggagcaggt ggacagtcag gcagcccagc
    15601 tggaagcatc cagaaaccag atcgcagcag caagaagtga actggagagt ggtttaagcc
    15661 aggtggagag cggactggcc cagcttgatg caaaggaagc agaactga
//
