LOCUS       c00217_gnlPro..         8992 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ELOGBILD_217.
ACCESSION   c00217_gnlPro..
VERSION     c00217_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 19:08:24
            Original ID  :: gnl|Prokka|ELOGBILD_217
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8992
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8992
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2627:8607]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2628..8607
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..8992
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8992
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             150..1439
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg217_1"
                     /sec_met_domain="SDH_alpha (E-value: 5.8e-63, bitscore:
                     201.8, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIESERKRIIDLIKKEVIPAIGCTEPIAVALCVAKAAETLGMKPE
                     KIEVLLSANILKNAMGVGIPGTDMVGLPIAVALGALIGRSEYQLEVLRDCTPEAVEQGK
                     LFIAEKRICISLKEDITEKLYIEVICTAGSQKATAVIAGGHTTFVYIATDEKVLLDKQQ
                     TANEEEEDASLELNLRKVYDFALTSPLDEIRFILDTARLNKAAAEQAFKGNYGHSLGKM
                     LRGTYEHKVMGDSVFSHILSYTSAACDARMAGAMIPVMSNSGSGNQGISATLPVVVFAE
                     ENGKTEEELIRALMLSHLTVIYIKQSLGRLSALCGCVVAATGSSCGITWLMGGNYNQVA
                     FAVQNMIANLTGMICDGAKPSCALKVTTGVSTAVLSAMMAMEDRCVTSVEGIIDEDVDQ
                     SIRNLTRIGSQAMNETDKMVLDIMTHKGGC"
     CDS             complement(1578..2153)
                     /locus_tag="ctg217_2"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYTVEDGEKELFEETNAEHPFQFISGLGTTL
                     ESFENQITALSKGDKFDFTIPADEAYGAYDEQHVFDLPKNIFEIDGKFDSERVTEGSIV
                     PLMTGDGQRVNASVVEIKPDVVVVDLNHPLAGADLIFEGEVIESRPATNEEIQELVKMM
                     SGEGCGCGCDSCGSDCGDDCGCEGGHCH"
     CDS             2628..4430
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg217_3"
                     /sec_met_domain="ILVD_EDD (E-value: 2.6e-218, bitscore:
                     714.6, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQLRSSFSTQGRRMAGARALWAANGMKKNQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQLVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADDSVSDQEVANIEQNACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRTKLFEDAAKLIVENAMKYYEEGDESVLPRSIATRQAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGVDFKMDDIDMLSRKTPCLCKVAPNTQKYHIQDVNRAGGIIAILAELAKGG
                     LIDTSVLRVDGMSLAEAIDQYSITSPNVTEKAMSKYSSAAGNRFNLVLGSQGAYYQELD
                     KDRANGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEA
                     ACEGILGGRVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIVDGDIIEIDIPARTINVRLTDEELAARPMTPVTRDRY
                     VPKSLKAYASMVSSADKGAVRLID"
     CDS             4478..6175
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg217_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.8e-48, bitscore:
                     152.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDLITGAEAMMRSLEHQGVTTIFGYPGGSIMPTFDALYDHQNT
                     LNHILVRHEQGAAHAAQGYARVSGKVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAG
                     QVGTGFLGTDAFQEVDLVGITQPIAKWSYQIRRAEDVAWAIARAFYIASSGRPGPVVLD
                     FAKNAQVEKTKYEPTKQEFIRSYVPVPDTDEESVKAAAELINNAERPLVLVGQGVELGS
                     AQEELRIFIEKADMPAGCTLLGLSALPTDHPLNKGMLGMHGNLGPNINTNKCDVLIAVG
                     MRFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDIAVLGDCKKTLAAVTGLLKKNR
                     HTEWVDSFKEYEAVEEEKVIRPELHPATDSLSMGEVVRAVSEATRHEAILVTDVGQNQM
                     ISARYFKYTRERSIVTSGGLGTMGFGLPAAIGATFGRPDRTVCVFMGDGGLQMNIQELG
                     TIMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKIASAYDIPSKRVF
                     SREELKAAIDEMLSTDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             6194..6757
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg217_5"
                     /sec_met_domain="ALS_ss_C (E-value: 3.8e-20, bitscore:
                     60.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDTIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQETP
                     EASKVIRRYNARIVEVNPVFSIVEKNGMSEEITSLYEELRALKCVLQFVRSGRVAITTS
                     CFERVNEFLDGQEAKYKQSKKEQE"
     CDS             6757..7500
                     /locus_tag="ctg217_6"
                     /transl_table=11
                     /translation="MSEENKIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHASDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYEKFSVQTWVENVYRLFTDRNFAVIDKDGK
                     KIGYARSVWAMINLNTRKPADLLALHGGSIVDYICDEPCPIEKPSRIKVTSNQPVATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYQTKRIRRFEMAYVAESYFGDELSFFCDEV
                     SENEFHVEVKKNGSEVVCRSKVIFE"
     CDS             7564..8607
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg217_7"
                     /sec_met_domain="IlvN (E-value: 2.3e-47, bitscore: 149.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.2e-40, bitscore: 128.0,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTVENVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQRQGKTYDKAVADGWVPGETLFGIEEACEKGTIIMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWSDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGNAMDRTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYHSVKTGNEAQISIDSNSKPDYREKLEEELKALRESEMWQTAVTVR
                     KLRPENN"
ORIGIN
        1 cgtgttttgc tttcactttt ctaccattct tactgttaaa gttcggttct tggaagattt
       61 tataacaatc tgcaatttta tttgttcact aatggatgtt tgataaaaaa gaattttcta
      121 cttttgtgga aactaaagcc ttatagggta tgattgaatc ggaaagaaaa cggataatag
      181 acttgatcaa aaaagaggtg attccggcga tagggtgtac ggaacccatt gcggtagcgc
      241 tttgtgtagc taaagctgcc gaaacattag gaatgaaacc ggaaaagatt gaggtgttat
      301 tgagtgccaa tatattaaag aatgcaatgg gagtcggtat ccccggcaca gatatggtcg
      361 gacttcctat agctgtagcc ttgggagcgt tgatcggccg atcggaatat caactggaag
      421 tgttgagaga ctgcacaccg gaggcagtag aacaaggcaa actgtttatc gcagagaagc
      481 gaatctgtat ttctctcaaa gaagatatta cggaaaaact gtacatcgaa gtaatctgca
      541 cagccggcag ccaaaaagcg acggctgtga ttgccggcgg acatactact tttgtctata
      601 tagctacgga tgaaaaagta ctgcttgaca agcaacagac tgccaatgaa gaggaagaag
      661 acgcttcact ggaactgaat ctgcgcaaag tctatgattt tgccctgaca tcccctctgg
      721 atgaaatccg ttttattctc gatacggcac gtctgaacaa agcagccgcc gagcaagcct
      781 ttaaaggcaa ttatgggcat tctttaggta agatgctccg tggaacgtat gaacataaag
      841 tgatgggtga cagcgtattc tctcatatac tatcttatac ttccgccgct tgcgacgcca
      901 gaatggccgg tgcaatgatt cccgtcatga gtaactccgg cagtggcaat cagggcatat
      961 ccgccacact tcccgttgtc gtatttgccg aagaaaatgg taaaaccgaa gaggaactga
     1021 tccgcgcctt aatgctgagt catctcactg taatctatat taaacaaagt ttgggacgtc
     1081 tctctgcctt gtgtggctgt gtagtagctg ccacgggttc cagttgcgga atcacctggc
     1141 tgatgggtgg aaactataat caggtagcct ttgccgttca aaacatgatt gccaacctga
     1201 cgggaatgat ttgcgacggt gcaaaaccga gctgcgcact caaagtaaca accggagtct
     1261 caacagccgt attatctgct atgatggcaa tggaggaccg ttgtgtgact tctgtagaag
     1321 gcattattga cgaagatgtc gatcagagca tccgtaactt gacaagaatc ggctcgcaag
     1381 ccatgaacga aacggataag atggtgcttg atatcatgac gcacaaagga ggatgttaac
     1441 aggtaataag taacaagtaa caagtaataa gtaataggta atagctggaa taacggcata
     1501 aaaaaagtat taagtattaa cttccgccta tatccgcatg gaattaatac ttaatactta
     1561 ttacctatta cttaaaatta gtggcagtgt ccgccttcgc aaccgcagtc atcgccacag
     1621 tcgctgccgc agctgtcgca tccgcaaccg caaccttcac cgctcatcat cttcaccagt
     1681 tcctgaattt cttcgttggt agcaggacgg ctttcgatta cttcaccttc aaagatcagg
     1741 tcagcgcctg ccaatgggtg gttaaggtca actactacta catccggttt gatttctacg
     1801 acgctggcgt ttacgcgttg accgtctccg gtcatcaaag gtacaatgct gccttctgtt
     1861 acgcgttcgc tgtcgaactt gccatctatt tcaaagatat ttttaggaag atcaaataca
     1921 tgttgctcat cgtaggctcc gtaagcttca tctgccggaa tggtaaaatc gaatttatca
     1981 cccttagaaa gagctgttat ctggttctcg aagctttcga gcgttgtgcc taatcctgaa
     2041 atgaactgaa aaggatgttc tgcatttgtt tcttcgaaca attctttttc accatcttcc
     2101 actgtatata gcttatatgc aacggtgatg tacttgtttt ctactgtttc catctgatat
     2161 ttatagtttc taattaataa atcccttatt tagggtggac aaagatacga ataatttgct
     2221 tgctaccggg tgcatacgga gtaaatttca gattattaag cgcttttgtc agaaatggac
     2281 agtcattctc tactaactga tagttgcaaa ttcaaccttt aagtgataaa atttaggttt
     2341 attaccgttc ttttcttacg attattcgct ttttagtgat ttttttcttc gatttgtttg
     2401 gagataataa aaaagccctt acctttgcag cacgaaaata aagaaaagaa gatatgaata
     2461 tattacatac atctattaac ctagcagttc tgcatattat tcgcgtcgtg gtggtgccat
     2521 caagagcgtg agaaaggttt tgtgtatgta ttcgtaccat aaaagataga atttggagcc
     2581 tttctcactg atgtgaggga ggctctttaa ttaaaagata gattgaaatg aaaaagcaat
     2641 tacgcagttc gtttagtaca caaggccgtc gcatggcggg agcccgcgca ttatgggcag
     2701 ccaacggcat gaagaaaaat cagatgggaa aacccattat cgctatcgtc aattcgttta
     2761 cacaatttgt tccgggacac gtgcacctgc atgaaatcgg gcagttggtg aaggcggaaa
     2821 ttgagaagct gggatgcttc gctgcggaat ttaatacgat tgctattgat gacggtatcg
     2881 ctatgggaca tgacggaatg ctttactcgc ttccttcccg tgatatcata gcggacagcg
     2941 tagaatatat ggtcaatgcg cacaaggcgg atgcaatggt atgtatcagc aactgcgata
     3001 agattacccc agggatgctg atggctgcca tgcgcctgaa tatccctacc gtatttgtat
     3061 ccggcggacc gatggaagcc ggagagtgga acggtcagca tctggacttg atcgatgcca
     3121 tgattaaatc agcggacgac agtgtaagcg atcaggaagt agcgaatatc gaacagaatg
     3181 cctgtcctac ctgcggatgt tgttccggaa tgtttacggc aaactcgatg aactgtctga
     3241 atgaagctat cggcttggct cttccgggaa acggcacaat cgtggctacg cacgaaaatc
     3301 gtacgaaact gtttgaagat gctgccaaac tgattgtgga aaatgcaatg aaatattatg
     3361 aagaaggtga cgaaagtgta cttccccgca gcatagctac ccgtcaggca ttcctcaatg
     3421 ccatgacgct ggatattgcg atgggcggtt ctaccaatac ggtgcttcac ctgttggccg
     3481 tggcacatga ggcaggagtc gatttcaaga tggacgacat cgatatgctg tcacgcaaga
     3541 caccctgcct gtgtaaagtc gctccgaata ctcaaaaata tcatattcag gacgttaacc
     3601 gtgcgggtgg catcattgct atcctggcag agttggcaaa aggcggtctg attgatactt
     3661 ctgttctccg tgtggatggc atgtcgctgg cggaagcgat cgatcaatat tcaattacca
     3721 gcccgaacgt aacagaaaaa gcaatgagca aatattcaag tgcggcagga aacagattca
     3781 atctcgtact tggttctcag ggagcttatt atcaggaatt agataaagat cgcgcgaacg
     3841 gatgtatccg tgatctggag cacgcctata gcaaggacgg aggcctggcg gtactgaaag
     3901 gaaatatcgc tcaggacggt tgcgtagtaa aaacggcggg tgtagacgaa agcatctgga
     3961 agtttaccgg acctgccaaa gtattcgact cacaagaagc agcctgtgaa ggcatcctcg
     4021 gaggccgagt cgtcagcggc gacgttgtcg tcatcacgca cgaaggtccg aagggcggtc
     4081 ccggtatgca ggaaatgctt tacccgactt cttatatcaa atcccgtcac ctcggcaaag
     4141 aatgtgcctt gattaccgac ggacgtttca gtggtggaac ttccggattg agtatcggac
     4201 acgtttctcc cgaagccgcc gccggaggta atataggaaa aatagtagat ggagatatca
     4261 tcgaaatcga cattcccgcc cgaacgatta acgtgcgact aacagatgaa gaactggctg
     4321 cccgcccgat gactcccgtc acccgtgacc gttacgtgcc gaagagcctg aaagcatacg
     4381 ccagcatggt aagctctgcc gataagggag cagtgagatt aatagactga tccacttcat
     4441 tatccattat gaatcatcca ttatccatta aagaactatg agtaaggact taataacagg
     4501 cgcagaggca atgatgcgct ctctggaaca tcagggagtg actaccattt tcggttatcc
     4561 cggcggttcc atcatgccta cgttcgatgc cctgtacgac catcaaaata cattgaacca
     4621 tatcttggtt cgccatgaac agggagctgc ccatgcggca caaggctacg cccgtgtatc
     4681 gggtaaagtc ggtgtttgct tggtgacaag cggccccgga gcaaccaata cgatcacagg
     4741 tattgcagat gcgatgatag acagtacgcc tatcgttgtc attgcaggac aggtgggaac
     4801 aggctttctt ggaacagacg cttttcagga agtcgatctc gtaggtatca ctcagccaat
     4861 cgctaaatgg agttatcaga ttcgccgtgc cgaagacgta gcctgggcga tagcacgtgc
     4921 tttctacatt gccagtagtg gtcgtcccgg tccggtggta ctcgactttg ccaagaatgc
     4981 gcaggttgaa aaaacgaaat acgagccgac aaagcaggag tttatccgca gctatgttcc
     5041 ggttcccgat acagacgaag aatcggtaaa ggctgccgcc gaactgatca ataacgccga
     5101 acgcccgctt gtcttggtag gacagggagt ggaactggga agcgctcagg aagaactgcg
     5161 tatctttatc gaaaaggcgg atatgcccgc aggttgtacc ttgctcggac tttccgcatt
     5221 gcctaccgac catccgttga ataaaggaat gctgggtatg cacggaaatc tgggaccgaa
     5281 tatcaatact aacaaatgtg atgtactgat tgctgtcggt atgcgtttcg acgaccgtgt
     5341 gaccggtaat ctggctactt acgccaaaca agcgaaagtg atccattttg acattgatcc
     5401 ggcggaagta aataagaatg taaaggtaga tattgccgtt ttgggcgact gcaaaaagac
     5461 gctggctgct gtgaccggac tgttgaaaaa gaaccggcac accgagtggg tcgatagttt
     5521 caaggaatat gaagcggtag aggaagaaaa agtcattcgt cctgaacttc atcctgcaac
     5581 ggattcactg agtatgggcg aagtggtgcg tgcggtaagc gaagcgaccc gtcacgaagc
     5641 catattggtg acagatgtag gtcagaatca gatgatctct gcccgctact ttaaatatac
     5701 cagggaacgt agtatcgtta cttcgggtgg actcggcacg atgggttttg gccttccggc
     5761 agctatcgga gctactttcg gccgtcccga ccgcacggta tgtgtattta tgggtgacgg
     5821 cggactgcaa atgaacattc aggagctggg tacgatcatg gaacagaaag ctccggtgaa
     5881 gattatctgc ctgaacaaca attatctcgg caacgtgcgc caatggcagg ctatgttctt
     5941 taatcgccgt tattcattta ctccgatgct gaatccggat tacatgaaaa tcgcttccgc
     6001 ctacgatatt ccttccaaac gtgtcttttc acgggaagaa ttgaaagcgg ctatcgacga
     6061 aatgctctcg acagacgggc cgttcctgct cgaagcctgt gtggtagaag aaggcaatgt
     6121 cctgccgatg acccctccgg gcggttcagt caatcagatg ttgctggaat gttaatcctt
     6181 aatttagaaa gttatgagtg ataagacatt atatacgatt atagttcatt ctgaaaatat
     6241 agccggattg ctaaatcagg tgaccgctgt atttacccgt cggcaaataa acatcgagag
     6301 tttgaacgtt tctgcttctt ccattaaagg agtacataaa tatacgatta cagcgtggac
     6361 tgataaggac actatcgaaa aggtggtgaa gcagatcgaa aagaagattg atgtgattca
     6421 ggcgcactat tttacggaag acgagattta tttccatgag atagccttat ataaggtatc
     6481 tactcctgct tttcaggaga ctccggaagc atctaaagtg atccgcagat ataatgcccg
     6541 cattgtagag gtgaatccgg tattctctat cgtcgagaag aacggcatga gtgaagagat
     6601 tacttccctt tacgaagaac ttcgggcttt gaaatgtgtg ctgcaatttg tccgttcggg
     6661 ccgtgtggct attactacca gctgtttcga acgtgtgaat gagttcctgg acggacagga
     6721 agcgaagtat aagcaaagta aaaaggaaca ggagtaatga gtgaagaaaa taaaataggg
     6781 acttatcagt ttgtggcaga gccgtttcac gtagatttta acggccgcct gaccatgggc
     6841 gtgctgggga atcatctgct gaattgcgca ggttttcatg ccagcgaccg tggatttggt
     6901 attgctacgc tgaacgagga caattacaca tgggtgcttt cccgcctggc gatcgagctg
     6961 gatgagatgc cttaccagta cgagaagttc tcggttcaga catgggtgga gaatgtctat
     7021 cgtctcttta ccgaccgtaa ctttgccgtc attgacaagg atggaaagaa gatcggctat
     7081 gcccgttccg tatgggcgat gatcaatctg aatacccgta agcctgccga tctgttggca
     7141 ttgcatggag gaagcatcgt cgattatata tgcgatgaac cctgcccgat agaaaagcct
     7201 tcgcgtatca aggtgacaag caatcagcct gttgcgacgc tgacggcaaa atacagtgat
     7261 atcgatatta acggacacgt aaacagtatt cgttatatcg agcacatact tgacttgttt
     7321 ccgatagaac tgtatcagac gaaacgtatc cgccggtttg aaatggcgta tgtggctgaa
     7381 agttatttcg gagatgaact ctctttcttc tgtgatgagg tgagtgaaaa cgagtttcat
     7441 gtagaggtga agaaaaacgg cagcgaggta gtatgccgtt ccaaagtgat atttgaataa
     7501 tatagagtat aaaatcaatt aataacagat ggcgcaagtc atcaaaacaa aaaaacaaaa
     7561 aaaatggcac agttgaattt tggcggaact gtagaaaatg tagttatccg tgatgaattt
     7621 ccattggaaa aagctcgtga agtattgaaa aatgaaacaa tcgctgtaat cggttatggc
     7681 gtacaaggtc ccggacaggc tctgaacctt cgtgataacg gtttcaatgt aatcgttggt
     7741 caacgccagg gaaagacata tgacaaagcg gttgctgacg gatgggttcc gggtgaaact
     7801 ttgttcggta ttgaagaagc ttgcgaaaaa ggtacgatca ttatgtgcct gttgtctgat
     7861 gcagcagtaa tgtctgtatg gcctactatc aagccttacc tgactgcagg aaaagctctt
     7921 tatttctctc atggttttgc tattacatgg agtgaccgca caggtgtagt tcctcctgca
     7981 gatatcgacg taatcatggt tgctcctaaa ggttcgggta catccttgcg tactatgttc
     8041 cttgaaggtc gcggcttgaa ctcttcttac gctatctatc aggatgcaac aggcaacgct
     8101 atggacagaa caatcgcatt gggtatcggt atcggttcag gttatttgtt cgaaacaact
     8161 ttcatccgcg aagctacttc cgacctgaca ggcgaacgtg gttcattgat gggagctatc
     8221 cagggtctgt tgctggcaca atacgaagtg ttacgtgaaa acggtcacac tccttccgaa
     8281 gcattcaacg aaactgtaga agagctgact cagtcattga tgccgttgtt tgcaaagaac
     8341 ggtatggact ggatgtatgc taactgctct actacagctc aacgtggtgc tctcgactgg
     8401 atgggcccct tccacgatgc tatcaaaccg gtagttgaaa agttgtatca cagcgtgaag
     8461 actggtaacg aagcacagat ttcaatcgac tctaactcca aaccggatta tcgtgagaaa
     8521 ctggaagaag aactgaaagc attgcgcgaa agcgaaatgt ggcagactgc cgtgacagtt
     8581 cgtaaacttc gtccggaaaa taattaatca gacttatact atataagttt ttcaaaaggc
     8641 gggaaaagcg tattttcccg ccttttctat gtagataccg gtcttttgag taatagaaaa
     8701 aggatgaaag tagaaaaaaa gattaaaaga tactgataat ataggtgaaa aagagcattt
     8761 atgatttcct gtacggcaac aaataaaaca gaataggcaa tgaagaaact ttttacttac
     8821 agaagatcga tacgtatgaa gatgatttct tctttaataa atagtatatc agaatgttac
     8881 attaaaagtt atttaagtta ttctctaccg aatggtagct gtaataccat ttcaagtcct
     8941 ttttatattt cgtgttccat tagtgattcg ttgatatgat gcagaatttt at
//
