LOCUS       c00050_gnlPro..        16852 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HIHJGBMA_50.
ACCESSION   c00050_gnlPro..
VERSION     c00050_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 21:22:26
            Original ID  :: gnl|Prokka|HIHJGBMA_50
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16852
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16852
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3381:6852]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3382..6852
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..16852
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16852
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(448..1671)
                     /locus_tag="ctg50_1"
                     /transl_table=11
                     /translation="MKSVKLASILFYLNSVFVVSCFVSCGSSPTEASSLLTADIRGGMD
                     KPGLLGLGDEIKGVTFVPLEVTTDDASLIDGVYDYAVTDRYIYVLPVKEPRIVLFDRQG
                     RFIRTLVKEGQGPGEFSGILPCIQVDERNDRFFLFSNNRVWEYTLEGEFIGQSTHEYSV
                     IYMRHIGKDRFAAISFPFQPFNGGGFGLGLFSRKGDTIAIKNDFYSFLLPHEKSGFTTS
                     IAPAYSDAQNSVLFKTGSNDTVFSISADRISAACVLDLKNSDAEVIRSLDVTDMSNLRI
                     EKKDPKDIFVQDMIEFPEHYYFRLLYNQGYYIASVDKKTGKTLVEKCEMPGSIYELADA
                     NLQHGMQGTRSYRNFPVWGRVIKDELVQVVTPYELNLYKSLRSITIPQELNLKGEEGNP
                     VFVFYSLI"
     CDS             complement(1781..3259)
                     /locus_tag="ctg50_2"
                     /transl_table=11
                     /translation="MGEVRACAPTHEIMRKEKAFLMNNLYTFAYMRKDLNGARHFSIGI
                     KFTILLFTIAILVLVLFSYRSDKHGNLFWQVEKLIPHHPDSALVLLEKVTDVNGLSLRE
                     KARYCLLWTESRDEAGLRHTSDSIISIATDYYRTTRGCYWPPKAWFYRGKVYEDMDQPS
                     LALECYLRALEYEGGNWDYEFWGRLYNQIGRLYAEQELYGKAMSFLRKASAQYQLLNDT
                     AGQGRILEEVKKYEALRDSIGSLSARESIYQITSRYDVRPVREDLYRKELMLSQRGQER
                     YLYAFIIGIILFICFLLYRRWRNTQENALRREEALRRSIASQQQRMREEKEENERQITL
                     LEKRITKIKEEKDQELMLVSLQLEKQRLEICNESIHNKESKHLLSVAILRKSEVYEKFH
                     DRDAGKIVSEDWELLEVLLNKAYDDFTLRLKKLYPAISDTELKVCMLTKIGVPANQITR
                     VLKYNSSVLRPRLFRKIFKKEGSTEAFVEFISSF"
     CDS             3382..4074
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_3"
                     /sec_met_domain="SucD_FumR (E-value: 1.4e-74, bitscore:
                     239.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLVLFLLFHLSMNVAAVFSGEAYNMV
                     CSLLGSNWYAVAATLVLAAGVVIHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGLIVILFMLLHFSQFWYKMMFAELIGHHEVALGSAMVSPQDGAAFINYYFQGNAV
                     ITVLYLIWYVALWFHLTHGFWSAIQTIGWNNTIWMNRWECISKIVATVICGLFAIITII
                     FFLNGVGA"
     CDS             4123..6066
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.5; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_4"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.5e-60, bitscore:
                     194.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-38,
                     bitscore: 122.0, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEINSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERYAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDNPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAIKDRIQKLMNVKGKETVDTIHRKLGHI
                     MWEHIGMARDAKGLQEAIQMLKDLKKEFWSNVFIPGNADNLNTELEKALRVADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     EFVVPQTRNYKK"
     CDS             6097..6852
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_5"
                     /sec_met_domain="Fer2_3 (E-value: 1.6e-26, bitscore: 82.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3.1e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDISVTLKVWRQRGPKEKGQFETYKIEKINQSVSFLEMLDILN
                     EQLVNEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFHDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFTSVNTGGVPDANAIPIPKKDADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             7275..8486
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_6"
                     /sec_met_domain="Radical_SAM (E-value: 9.1e-17, bitscore:
                     51.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKRTTSSFRAMSTERKLESIFLFVTGRCNAKCAMCFYAQEMDK
                     KQPDLTFDEIKKISETAGQFNRLWISGGEPTLREDLPEILELFYKNNHIKDVNIPTNGL
                     KPDRIVEWVKRFRQNCPDCNINVSLSLDGFGTTHDTQRGVPGNFYKALETLRKIQENFG
                     DDGKVLKNIATVITKYNIDQIEDFMTWVYGRFRTSTHTIEAARGMTRDDGVKILTESTL
                     RKIQDDISPIYSAYADRMVADTTGLRKPITRFFYLGLIRTLYNVRASNIDHPTPWGMDC
                     TAGETTLVIDYDGRFRACELREPLGNIKEYGCDISKVMNSEAMKQEIAAIGHGYKANCW
                     CTHGCWITSSVIFNPRKMIRSVYKGYRETKRLNHPLAINEQKLQTMEAKYHLDIERLRQ
                     LNIR"
     CDS             8520..9752
                     /locus_tag="ctg50_7"
                     /transl_table=11
                     /translation="MKILLVTRGSQGDVLPYLAIAAELERRGHEVTINLPQIFEETVKP
                     YGFKYVLQQFDDIGGMIDSAAQNSHKFRPFLKWMRNVIDKQFDQLIPLLKEHDILVSTN
                     SEFAVASIAEYCKKPLIRTAYAPFLPGKKIPPAVLPFPKPNPIITPAILWKLMNRMTNF
                     MVKDTINKNRAKYGLAPIRNFGYHAGERSYNYLLFSQHLGNIDPDWTFKWSIGGYCFND
                     TFQYDEKAYEEMISFVDSAQSPIIFFTLGSCSSKDGNRFSKALVDICKKHDYRLIIGSG
                     WAKTGITLQADKHLFLMKQPVPHNLIFPHCDGVIHHGGCGTTHSVGRAGKPQLITPLII
                     DQPYWSYRIHQLGLGPEGVKIAKASEQEIERKVCDLVTNPLYKKNAAHIGEMIQKEGGI
                     KNICDSIERFQ"
     CDS             complement(9958..13095)
                     /locus_tag="ctg50_8"
                     /transl_table=11
                     /translation="MIRNIINLKAIILYFGLILCLIAGMPTPAYGSSSYPVKEESYVLV
                     INSYVDGERWSGNLLNMISKFATPEEYTLRIDHISVMLVDTPEKLKEKQEVFFEANKKK
                     PDGIIYLGVNGWAFMRDKIREKWGDIPTLVCSETGEMAENECYFNQRHSSDRVIPLQEA
                     VKGYNATGLVIPYYVKGSIDLVKELIPGLKRLIFISDRRYVSTWLRDEMEKHMETSFPE
                     GKVDFYTEGSCSMDSLMAVLSEKDPHRATAVMYYSWITEKPFLNHSLLYSTLYQGINGI
                     SRHPVFSLYDMGVEEGYTIGGYYNSSKTIETALIPLLQQVYNGEDMGKIPVSTVDDPHK
                     YLNYVSLMSAMSNEDNFPHDAIYLNAPPSFLEKYWMPLLGFLIFFLVVVFLAWHYVYRS
                     KQKMKEVELRLLSRYRDLFNNMPLPYIRQRLIREGTQIDVQVLDVNHAFEEKIAPKDFV
                     VNKHGKEIANLIGGSYPLLLSAVPTVLESGKSFTCEYYFEPTGLYYTIIIMPTSEENVV
                     DAFFIDITDIHKFQTHLKAMNHKLAMALEAADLLPWRYNLAEGKIIYESKVHPEDNIET
                     AEIHTHEVSLKEYFSKIHPSFRACVEKAFDDLCNGKIKKVRKEYCLERLIPGEDRHEWE
                     EIQVMAEYDASGEPKALIGSTISITERKQLEHDLRMARDKAEESNKLKSAFLANMSHEI
                     RTPLNAIVGFSNILASTDDLEDKKEFADIIENNNSLLLQLINDILDLSKIEAGTLEFTY
                     DYVDINAVLRDLEQSAHLKNKNPDVQISFKDYLEPCVIYTDRNRLSQLMINLLNNAMKF
                     TLAGSILFGYKLKDDNTLWFYVEDTGCGIPENKRKDIFGRFVKLNTFAQGTGLGLSICE
                     MIVTQMKGTIGVDSMEGKGSKFWFTLPFQPKKELFPSEEQKPVTLEKIARSEVTILIAE
                     DNSSNYRLFESILKPEYKLIHAWNGKEAVELFHQHKPQLILMDIKMPVMDGYEATAEIR
                     KVSASVPIIAVTAYAFAQDEQRIINSGFDAYTAKPINGKILKDKISTLLTHRIILM"
     CDS             13326..14102
                     /locus_tag="ctg50_9"
                     /transl_table=11
                     /translation="MELMDMKDYDIDFKEKRTSGYLIATLFIIVGILFLLRNLGMIDPS
                     LFDLLVSWPMLLVVSGIFTIFHRNPVGGMLLVGVGVYFLFPQLNWITNDFLRVYWPLGL
                     ILLGLVIMLKRKDSIRTKKHKRPFNHPPFGHRKPNDEINYETDNGFVSVDTTFNSVRHI
                     VLDPVFKGADIDVSFGNVILDLKKTTLEADETIINIDSSFSGVVIYVPKGWLVRLKVDS
                     FLAGCQDMRDLTETTDMTHTLYICGDLSFSGLELRD"
     CDS             14110..14904
                     /locus_tag="ctg50_10"
                     /transl_table=11
                     /translation="MQEHPITTSILHKGLGSLLLLLAIAIQCALLTLYGDLPLSITLID
                     SLLSIALFAVAGYYLWYVQCTLHIMQARVAFAVLVQIACIAGCSILLQIFGLEDWEEFS
                     ITIPFRFLFGLMAWIILSQWYASRERKSEAEPIVRQMEEKTAPPPTTVPEEILDRISVK
                     DGARIHIIPIKEIFYLQACGDYVTLFTTSGQHVKEQTMKYFERSLPSPEFVRIHRSYIV
                     NTEQILRVELFGKETYQVRLKDGTYLRASSAGYKLLKERLSL"
     CDS             complement(15242..15760)
                     /locus_tag="ctg50_11"
                     /transl_table=11
                     /translation="MKKYWHIALMLFCVFMITSCGDDDEALEVDEVWKVQNEEAFQAQM
                     LVPGFEQLSSQSNAGFILYKVLKTGESKEPIYYTSKVECYYKGTFIDGTVFDDKSFEAG
                     APAELTVSEMVDGFATALQNMHPGDRWEIWIPQQMGYGSAGRSASGSVIIKPYTTLIFD
                     LEVTRIVKE"
ORIGIN
        1 aaatttaaac aaattattaa tatgaattcc gttgcatttg gaacttgaat tcagcttatt
       61 tataccgtta ttacacatac ttaccaacct ctaagcatat ccggatatta cgttggtttc
      121 gcaaatatac gaaatactcg taatataaat ataaacaata cgttaattaa cactaatagc
      181 catcaaaggc atagaaaaga taaaagaaca cgattattta ccgaacagtt aaaatacaca
      241 atatgcccac tttgcacgta aatattagta tatggctgat atctacgcag ttatacatac
      301 acgcctatta ccgatccaat tactatctat aataaatcag attactatca atagtaaatc
      361 agattttcta tagatagtaa ccatgaatac tatagcttct atcgctagat tattacaaga
      421 agtacaaccg agcgatacat atcgaagtca gataagcgaa taaaacacaa aaaccggatt
      481 gccctcctct ccttttaagt tcaactcctg cggaatcgtg atcgagcgaa gcgatttata
      541 taagtttagc tcatacgggg tcactacttg taccagctca tcttttatga ccctccccca
      601 gaccgggaaa ttccgataac ttctcgtacc ctgcatgcca tgttgaaggt tcgcatccgc
      661 cagttcatag atagaacccg gcatctcaca tttttccaca agtgtctttc ccgtcttttt
      721 atctacagag gctatataat agccttggtt atacaataag cggaaataat aatgttccgg
      781 aaactcaatc atatcttgca caaagatatc cttggggtcc tttttttcaa ttcgcaaatt
      841 actcatgtcc gtaacatcca acgaacgaat cacttccgca tccgagtttt tcagatcaag
      901 gacacaagcc gcacttattc gatccgccga gatactgaag accgtatcat tgctaccggt
      961 cttaaacaac acggagtttt gcgcatcaga ataagcgggg gcgatacttg tcgtgaaccc
     1021 gctcttctca tgaggtaata aaaaggaata aaaatcattc ttgatcgcta tcgtatcccc
     1081 tttcctcgaa aataggccta atccgaatcc tcctccgttg aaaggctgaa aagggaatga
     1141 tatggcggcg aaacgatcct ttccgatatg acgcatatag attacagaat actcatgggt
     1201 ggattgtccg ataaattcac cttccaacgt atattcccaa actcgattat tactaaataa
     1261 aaaaaagcgg tcattacgtt cgtccacttg gatacatggc agaataccgc taaattcacc
     1321 cggcccctgc ccttctttta ccaacgtccg gataaaacgc ccttgccgat cgaacaggac
     1381 gatacggggc tcttttacgg gaagcacata gatatatcga tctgtcacgg cataatcata
     1441 aactccgtct atcaacgagg catcatccgt ggtcacctct aaagggacaa aagtaacccc
     1501 cttgatctca tcgcctaatc ccaatagccc cggtttatcc atcccccctc ttatatccgc
     1561 agttaaaaga gaggacgctt ccgttggcga agaaccgcat gacacgaaac aagaaacgac
     1621 aaaaacacta tttaaataaa acaagataga ggctaacttt acacttttca taaccatgct
     1681 tttttgcctc caaaaatatc ccgcatatct cacaaatcac atgataaatg agaacaaaaa
     1741 tgagaacaaa cctgccaaga ccgctataaa tacataataa tcaaaaactt gagataaact
     1801 ccacaaatgc ctccgtagaa ccttctttct taaaaatctt ccggaacaga cgaggacgaa
     1861 gtaccgaact attatatttc aatacccgtg tgatctggtt ggcgggaacg ccgatcttcg
     1921 taagcataca gaccttcaac tccgtatcgg aaatagcagg atatagtttt ttcagccgta
     1981 aggtaaagtc atcataagcc ttattcaaca gcacctccaa aagctcccaa tcctcagaga
     2041 caatcttgcc ggcatcccga tcgtggaact tctcatagac ctccgatttc cgcaagatcg
     2101 cgacagataa taaatgctta ctctccttat tatgaatcga ctcgttacaa atctccagcc
     2161 gttgtttttc caattgtaag gaaaccaaca tcaactcttg atccttttct tcctttattt
     2221 tcgtaattct tttttccaaa agggtgattt gccgttcatt ctcttctttt tcttctcgca
     2281 tacgttgttg ctggctagca atcgaacgtc gcaaggcttc ttcccttcga agagcgtttt
     2341 cctgcgtatt tctccatcgc cgataaagga ggaagcaaat aaataggatt atgccgataa
     2401 taaacgcgta cagataacgc tcctgtcccc tttgcgataa catcaattct ttcctatata
     2461 agtcctcacg aaccggcctt acatcatacc gggaagtgat ctgataaatc gattctctcg
     2521 ctgacagcga tccgatagaa tcccgtaacg cctcgtattt cttgacttcc tccagtatcc
     2581 ggccttgtcc ggccgtatca ttcaagagct gatattgggc actcgctttt ctcaaaaaag
     2641 acatagcctt gccatataat tcctgctcgg cgtacagcct ccctatctgg ttatataacc
     2701 gtccccaaaa ttcgtaatcc caattccctc cctcatattc caacgcacgt aaatagcatt
     2761 ccaaagctag ggacggttga tccatatcct catagacttt cccccggtaa aaccacgctt
     2821 tgggaggcca gtaacagcct cgtgtcgtcc tataataatc cgtagcgata gagattatgg
     2881 aatccgatgt atgcctcaat cccgcctcat cccgtgattc ggtccataac agacaataac
     2941 gggctttctc tcgaagcgat aatccattga catccgtcac tttctctaat aacaccaaag
     3001 cgctgtccgg atgatgcgga atcaatttct ctacctgcca gaacaggttg ccatgcttgt
     3061 cgctcctata cgaaaaaagc acaagaacca agatcgcgat cgtaaacaat aagatcgtaa
     3121 acttgatccc tatagaaaaa tgccgtgccc cattcaaatc cttacgcata taggcaaatg
     3181 tatataaatt attcataagg aaagcctttt ccttccgcat tatttcatgt gtcggggcac
     3241 atgccctgac ctctcccatt aatgcagaaa tatttcttta atcgtttgcg caatatatgg
     3301 atttagcata cctttgcgtg ataattacat agtttaagta gaaatttcta aatacaatta
     3361 aataacttaa attattatct tatgtggtta cttaattctt ctatcgggaa gaagctgata
     3421 atgagtatat caggcctctt tcttgttctg ttcttattgt tccacctgtc gatgaacgtg
     3481 gcggccgttt tctccggaga ggcttataac atggtttgtt cgctgttggg ctctaattgg
     3541 tacgctgtgg cagctactct cgtattggcc gcaggcgttg tgatccactt cgtgtacgct
     3601 atcattctta ccttgcaaaa ccgtaaggca cgtggtaacg accgttacgc tatcaacgct
     3661 cgtccgaaag gcgtggaatg ggcatctcag aacatgttcg ttttgggttt gatcgttatc
     3721 ctgttcatgc tgttgcactt cagccagttc tggtataaga tgatgttcgc cgaattgatc
     3781 ggtcatcacg aagttgcatt ggggtcagct atggtatctc cacaagacgg agccgctttt
     3841 atcaactatt acttccaagg taatgccgtg atcaccgttc tttatttgat ctggtacgtg
     3901 gctttgtggt tccacttgac tcacggtttc tggagcgcta tccaaacaat cggttggaat
     3961 aacacgatct ggatgaaccg ttgggaatgt atctctaaga tcgtagctac ggttatttgc
     4021 ggacttttcg caatcattac tatcatcttc ttcctaaacg gagtaggtgc ttaattgcaa
     4081 gctacaggtt ttataattaa gaacttttga aattaaatca ttatgtctga aataaattct
     4141 aaaatacctc aaggcccgtt ggctgagaag tggactaatt ataaaaatca ccagaaattg
     4201 gtgaaccccg ctaacaagcg tcgtttggat gttatcgtag tcggtacagg tttggctgga
     4261 gcttccgctg ccgcatcttt ggcagagatg ggattcaacg tattgaactt ctgtatccaa
     4321 gattctcccc gccgtgcgca ctctatcgcc gctcaaggtg gtatcaacgc cgctaagaac
     4381 taccagaatg atggtgactc tgtttaccgt ttgttctacg atacgatcaa aggtggtgac
     4441 taccgtgctc gtgaggctaa cgtttatcgt ttggctgagg tttctaactc aatcatcgac
     4501 cagtgcgtgg ctcaaggcgt tcctttcgct cgcgaatatg gtggtttgtt ggataaccgt
     4561 tcattcggtg gcgctcaggt atcgcgtacg ttctacgccc gtggccagac gggtcagcag
     4621 cttttgttag gcgcttattc agcgttgagc cgtcagatcg gtttgggtaa ggttaagatg
     4681 tacactcgtc atgagatgtt ggatgtagtt aaggtagacg gtcgtgctcg tggtatcatc
     4741 gcccgcaact tgattacagg taagatcgag cgttacgccg ctcacgctgt agttgtagct
     4801 acgggtggtt acgttaatac gttcttcttg tcaaccaacg ctatggcatc taacggttcc
     4861 gccgcatggc aatgctacaa gaaaggcgct tacttcgcta atccttgtat ggttcagatc
     4921 cacccgactt gcgtaccggt gaaaggtgac ttccaatcta aattgacttt gatgtccgaa
     4981 tccttgcgta acgacggccg tatctgggtt ccgaagaaac tggaagacgc taaagctcta
     5041 caggccggaa cgaagaaagg taaagatatt cccgaggcag accgtgatta ttatttggag
     5101 cgtcgttatc cggcattcgg aaacttggtt cctcgcgacg tggcttctcg tgccgctaaa
     5161 gagcgttgcg acgcaggttt cggcgtgaac agcacgggct tggccgtatt cttggatttc
     5221 tccgacgcga tcaatcgctt gggtaaagag gtcgttaagc agaaatacgg taacttgttc
     5281 gatatgtacg aagagatcac gaacgataat ccatacgaga ctccgatgat gatctacccg
     5341 gcattgcact actcaatggg tggattgtgg gttgactatg agttgatgac ctccattccg
     5401 ggtctgttcg ctatcggtga ggcaaacttc tccgatcacg gagcgaaccg tttaggtgct
     5461 tccgctttga tgcagggatt ggccgatggt tatttcgtat taccatacac gatccagaac
     5521 tatttgtccg accaaatcca agttcctcgc ttcagcacgg atctgccgga gttcgtcgag
     5581 gcagaaaagg ccatcaagga tcgtatccaa aaattgatga acgtcaaggg taaagaaacc
     5641 gtagacacta tccaccgcaa actaggtcat atcatgtggg aacatatcgg tatggcacgc
     5701 gacgcaaaag gtttgcaaga agctatccag atgctgaaag acttgaagaa agagttctgg
     5761 agcaacgtat tcatcccagg caacgcagac aacttgaata ccgagttaga gaaagcatta
     5821 cgtgtagccg actttatcga gatcggtaca ttgatggcac acgatgcttt ggaccgcgct
     5881 gagtcttgtg gtggtcactt ccgtacggag caccagacag aagaaggtga ggccttgcgt
     5941 catgacgata agttcatgta cgtatcttgc tgggagtacc aaggcgagga caaagatcct
     6001 gtcatgttga aagaggattt gaactatgag ttcgttgttc ctcaaacacg taactacaag
     6061 aagtaataat catcaatctc agaaaaaatt agaatcatgg ataaagatat aagtgtaaca
     6121 cttaaggttt ggcgtcagag aggtccgaag gagaaaggac agttcgagac atacaaaatt
     6181 gagaagatca atcagagtgt ctctttcttg gaaatgttgg atatcttgaa cgagcagttg
     6241 gtcaacgagg gtaaggaacc gatcgtattc gatcacgact gccgcgaggg tatctgtggc
     6301 atgtgttcat tgtatgtaaa cggacacccg cacggaccgg caactggagc tacgacttgc
     6361 cagttatata tgcgtcgttt ccacgatgga gagacgatca cgatcgaacc gtggcgttcc
     6421 gcaggtttcc ctgttatccg cgacttgatg gtagaccgct acgcttacga caaaatcatc
     6481 caagcgggtg gtttcacatc tgtcaacaca ggtggtgtac ccgacgctaa tgcgatacct
     6541 atcccaaaga aggacgcaga cttagccatg gacgctgccg cttgtatcgg ttgtggcgct
     6601 tgtgccgccg cttgtaagaa cggttcagct atgttgttcg tatccgctaa ggttagccag
     6661 ttggctttgt tacctcaagg taaagtcgag gctgctcgtc gtgcgaaagc aatggtcgct
     6721 aaaatggatg aacttggctt cggtaactgt acgaacacac gtgcttgcga gatggaatgt
     6781 ccgaagaata tctccgttag caacatcgct cgtttgaacc gtgagttcat ttgcgctaaa
     6841 ttacaagact aatatttgat tagtatatca tggaaaaggc gtctttctct aaaagaaagg
     6901 cgccttttta tttttgttat atgttgaaaa acataattta gcactacaga tcttgacagg
     6961 aattgaaaag tccgtatatt tgtatcgtgg ttttttcata atagtattag atttaaggtt
     7021 aacaaagttt ggttagggct tgtcgtgaga caggctttaa ttgtttatag acctaccttt
     7081 taaacatgga ccataaaata ctgcaaatag agattgttta gcgtcatttt atcgtcgatc
     7141 tttgccttta aagatcatat agtatatgct aataagtatt ttatttggct tcttatgtta
     7201 ttttctccgg gtgttgatca aacacaagga aaaaatcatg cgccagataa gacaaatggt
     7261 aaaacaaaaa taaaatggac aaaaaacgaa ccaccagttc tttcagggca atgagcacgg
     7321 aaagaaaact cgagtcgatc ttccttttcg taacaggccg atgcaacgcc aaatgcgcga
     7381 tgtgtttcta tgcccaagaa atggataaga agcaacccga cctcactttc gatgaaatca
     7441 agaagatatc agaaaccgcc gggcaattca atcgattatg gatatccggg ggtgagccta
     7501 ccttgcgtga ggatctaccg gaaatattgg agttattcta caaaaacaac catatcaaag
     7561 atgtgaacat ccctacgaac ggcttaaaac cagaccggat cgtcgaatgg gtaaaacggt
     7621 tccgccagaa ctgcccggat tgtaatatta acgtaagcct ttccttggat ggtttcggta
     7681 cgacccacga tacacagaga ggcgtaccgg gaaacttcta taaggcactg gaaaccctgc
     7741 gtaagataca ggagaatttc ggagacgacg gcaaggtcct gaaaaatata gcaaccgtta
     7801 tcacgaaata caatatagac cagatagaag acttcatgac ttgggtatac ggacgtttcc
     7861 gtacctccac gcatacgatt gaggctgcca gaggcatgac ccgtgacgat ggcgtgaaaa
     7921 tcctaaccga gtcaacgcta cgcaaaatac aagatgacat atcccctatc tattctgctt
     7981 atgcggatcg gatggtagcg gataccaccg gcttaaggaa accgatcaca cgcttcttct
     8041 atctcggcct tatacgtacc ttatataatg tgcgtgccag caacatagat cacccgaccc
     8101 cttgggggat ggattgtacg gccggagaga ctaccttggt aatcgactac gacggacgtt
     8161 ttcgtgcctg cgagctacgg gaaccgctcg gaaatataaa agaatatggt tgcgatataa
     8221 gtaaagtgat gaatagcgaa gcgatgaaac aggaaatagc cgctatcgga catgggtata
     8281 aagccaactg ttggtgtacg cacggctgct ggatcacctc atccgtcatt ttcaatccac
     8341 gtaagatgat tcgctccgta tataaaggat accgggaaac gaaacgattg aatcatccct
     8401 tagccatcaa tgagcagaaa ctacaaacga tggaagccaa ataccatctg gacatcgagc
     8461 gtttgcgtca actgaatatc cggtaaacaa gaccctcata gcccataaat aaacgtagca
     8521 tgaaaatact attagtaacc agaggctcac aaggcgacgt ccttccttat ttggccatag
     8581 cggccgaatt ggaaagacgc ggtcatgagg tgaccatcaa tctccctcaa atattcgagg
     8641 agaccgttaa accctacgga tttaaatacg tattgcaaca gtttgacgat atcggcggca
     8701 tgatcgatag cgcagcgcaa aactcacata aattccggcc attccttaaa tggatgcgga
     8761 acgtgatcga taaacagttc gatcaattga ttcccctact aaaagagcat gatattttag
     8821 tatcgaccaa ctcggaattt gctgtcgcaa gtatcgccga gtattgcaag aagcccttga
     8881 tacgtaccgc ctacgccccg ttcttgccgg gtaagaagat tcccccggcc gtattgccat
     8941 ttcccaaacc caacccgatc atcacccctg ccatcttatg gaagttgatg aaccggatga
     9001 ccaatttcat ggtcaaagac acgatcaaca agaaccgggc taaatacgga ctcgcaccga
     9061 ttcgtaattt tggttatcat gcgggagagc gttcatataa ttacttgctt ttcagccagc
     9121 acctaggaaa catagatccg gactggacgt tcaaatggtc gatcggaggc tattgcttca
     9181 atgacacttt tcaatatgat gagaaggctt acgaggaaat gatatcattc gtcgacagcg
     9241 ctcaaagccc tattatcttt tttaccctcg ggagttgtag ttccaaggat ggtaaccgtt
     9301 ttagcaaagc cttggtcgat atttgcaaga aacatgatta tcggctcatc atcggttccg
     9361 gttgggcaaa gacaggaatc accttacaag cggataaaca tttattctta atgaagcagc
     9421 cggttccgca taatttgata tttccgcact gcgacggcgt tatccatcat ggaggttgcg
     9481 gcacgaccca tagcgtagga agggcgggaa agccccaatt aatcactccg ttgattatcg
     9541 atcaacccta ttggtcctat cgaatccacc aattagggtt agggccggaa ggggttaaga
     9601 tagcgaaagc gagcgagcag gagatcgaac gcaaggtttg tgatctggtc accaatccgc
     9661 tttataagaa aaatgccgct catataggcg agatgatcca aaaagaggga ggtataaaga
     9721 atatatgcga ctctatcgaa agatttcaat gaggcataag ttcctattag attttattac
     9781 atgttacaaa acacaattta gcacttaaac tattgacaaa tagcggtaac tccgtatatt
     9841 tgcatagtgg ttttttcata atagtattag atttaaggtt aacaaagttt ggttagggct
     9901 tgtcgtgaga caggctttaa ttgttttata aggtctgctt cccgcaaagc ccttcgatta
     9961 catcagaata atccgatgcg tcaataaagt tgatatcttg tcttttaaga tcttcccatt
    10021 aatcggtttc gccgtatagg catcaaatcc actattaatg atccgttgct catcttgggc
    10081 gaaagcataa gccgtcaccg caataatagg cacgctagca gaaaccttac gaatctctgc
    10141 ggtagcctcg tatccatcca tgaccggcat ctttatatcc atcaagatca actgcggttt
    10201 gtgctgatga aatagctcca cagcctcctt tccattccat gcatgaatca atttatattc
    10261 aggcttcaat atagactcaa acaggcgata attactggaa ttgtcctcag cgatcaagat
    10321 cgtaacctca cttcgggcga tcttctccaa agtaacaggc ttctgctctt cactaggaaa
    10381 taattctttc ttcggctgaa aaggcaatgt aaaccagaac ttagagcctt tcccttccat
    10441 agaatcaacc ccgatcgttc ctttcatctg ggtaacaatc atctcgcaga tgcttaaacc
    10501 cagtcctgtt ccttgagcga aagtattcag ttttacaaaa cgtccgaaaa tatctttccg
    10561 cttattctcc gggattccgc agcccgtatc ctctacatag aaccacaacg tattatcatc
    10621 cttcaactta tagccaaata aaatcgatcc tgccagcgta aatttcatgg cattgttcaa
    10681 cagattgatc atcagttgag acagacgatt tcgatccgta taaatcacgc aaggctccag
    10741 ataatcctta aatgagatct gtacatccgg attcttattc ttcaaatgag ccgattgctc
    10801 caaatccctc aatacagcgt taatatccac atagtcataa gtaaactcca aggtacccgc
    10861 ctcgatcttt gacaaatcca agatatcgtt tatcaactgc aacaataggg aattattatt
    10921 ctcgataata tcagcgaatt ccttcttatc ctcaaggtca tcggtcgagg caaggatatt
    10981 agagaaacct acgatcgcat ttaacggtgt acgtatctca tggctcatat ttgctaaaaa
    11041 cgctgatttc aatttattcg actcttccgc cttatcccta gccattcgaa ggtcatgttc
    11101 caattgctta cgctcggtaa tagatatcgt agaaccgatc aacgctttcg gttcaccgga
    11161 agcatcatat tcagccatta cctgtatctc ctcccactca tggcgatctt ctcccggaat
    11221 caaccgctcc agacaatatt cttttcgtac tttctttatt ttcccattac acaaatcatc
    11281 gaaagccttt tccacgcaag ccctgaaaga cgggtgtatc ttgctgaaat attccttcaa
    11341 cgaaacctca tgggtatgta tctcggcagt ctctatatta tcttccggat gtactttcga
    11401 ctcatagata atcttccctt cagccagatt atatcgccac ggtaaaagat ctgccgcctc
    11461 taacgccata gccagcttat gattcatggc tttcaaatgc gtctggaatt tatggatatc
    11521 cgtaatatca ataaaaaacg cgtcaactac attctcttcc gaggtaggca tgatgataat
    11581 cgtatagtaa agccctgtcg gctcaaaata atactcacaa gtaaaggatt tcccactctc
    11641 cagaactgta ggcacagccg atagaagcaa aggataactt cccccaatta aattagcgat
    11701 ctcttttcca tgcttattta ccacgaaatc tttaggagcg attttttcct cgaaagcatg
    11761 gtttacatcc aaaacctgca catcgatttg cgtaccttcc cgaatcagcc gctgccgtat
    11821 ataaggcaat ggcatattat taaataaatc acggtaacgg gataatagcc tcaactccac
    11881 ttccttcatc ttttgcttag aacgatacac gtaatgccac gctaaaaaca cgactaccag
    11941 aaagaaaatc agaaagccta atagcggcat ccaatatttt tctaaaaaag agggaggcgc
    12001 attcaaatag atcgcatcat gtgggaaatt atcttcatta gacatcgcgc tcatcagcga
    12061 aacataattc aagtatttat gaggatcatc caccgttgaa accgggatct tgcccatatc
    12121 ttcaccgtta taaacttgct gtagcaaggg aattagagct gtctcaatcg ttttagagct
    12181 attataatat ccaccaatcg tatatccttc ttccacgccc atatcatata aagaaaaaac
    12241 aggatgccta gaaatgccgt ttataccttg atacaaagta ctatataata acgagtgatt
    12301 caagaaaggt ttctcggtaa tccacgagta atacatcacg gccgtcgctc gatgtgggtc
    12361 tttctccgac agaaccgcca ttaaactatc catggagcaa gaaccctccg tataaaaatc
    12421 cactttcccc tcagggaaag aagtttccat atgtttctcc atctcatccc gaagccatgt
    12481 ggagacataa cgtctgtcgg atatgaaaat cagacgtttc aaacccggga ttaattcctt
    12541 caccaagtcg atcgaacctt taacataata agggataacc aagcccgtag cgttataccc
    12601 cttaaccgcc tcttgtaaag gaatcaccct atcagaggaa tgcctctgat taaaataaca
    12661 ttcattttct gccatttccc ccgtctccga acagaccaga gtgggaatat ccccccattt
    12721 ctcccggatc ttatcccgca taaaagccca tccatttacg cctaagtaga taattccatc
    12781 cggcttcttc ttgttagctt caaagaagac ctcttgtttc tcttttaatt tctctggcgt
    12841 atcaaccaac atcacgctta tatgatctat ccggagagtg tactcctccg gggtagcgaa
    12901 cttcgagatc atgtttaata aattaccaga ccaacgttcg ccatccacat atgaatttat
    12961 caccaataca tacgattcct ccttgaccgg atatgaagaa ctcccataag ccggagtcgg
    13021 cataccggct atcaagcata aaatcaatcc aaaataaagt attattgcct ttaaatttat
    13081 aatatttcgt atcattccct acattcctct attgcagttg taaagacaaa gatattcctt
    13141 aattatcaac taatcttatc aaactagttt ttttatcaag ttttggtgtc aaattcacgt
    13201 ttcttacaaa ctaaaggctt ttttaatcgg gattattcgg ttatttaccg atactcgtat
    13261 agaaatcagc ggtatttact tgtgtataga atgacgaacc cgtacatttg ataaaaaaca
    13321 aaaaaatgga acttatggat atgaaagatt atgacatcga ttttaaagag aagaggacaa
    13381 gcgggtatct gatcgctacc ttatttatca ttgtcggtat attattttta ctgcggaatc
    13441 taggaatgat agatccatcc ttatttgact tgcttgtatc ttggccgatg ctgcttgtcg
    13501 tgtcgggcat ctttacgatt ttccaccgta atccggtagg aggtatgctc ctcgtaggcg
    13561 tgggagtcta tttccttttc ccgcagttaa attggatcac gaacgatttt ttacgtgtat
    13621 attggccgtt aggattaatc ctgttaggat tggtcatcat gctgaagcgg aaagattcta
    13681 tccgcacgaa aaagcataaa cgtcccttta accatccccc tttcgggcac agaaagccta
    13741 acgatgagat caactacgag acagataacg gtttcgtatc ggttgacacc actttcaact
    13801 cggtaaggca catcgtactg gaccccgtat tcaagggggc ggacatagac gtatctttcg
    13861 gcaatgtgat cctcgatctt aaaaaaacaa cattagaggc tgatgaaacc atcataaaca
    13921 tagatagctc cttcagcggc gtagtaatat atgtccctaa aggatggctg gttcgtctaa
    13981 aggttgattc cttcttggct ggatgccaag atatgaggga cctgacagaa acaaccgaca
    14041 tgacgcacac gttgtatata tgtggagact tgtcgttcag cggccttgaa ctaagagact
    14101 aaactcatca tgcaagaaca tcctattaca acatccatat tacataaagg gctgggaagc
    14161 ctattattac ttttagccat agcgatccaa tgcgcattat taactcttta tggcgatctt
    14221 ccgttgagca tcactttgat cgatagctta ctttccatcg cattgttcgc cgtagcggga
    14281 tattatcttt ggtatgtaca atgtacgtta catatcatgc aagcacgagt ggctttcgcc
    14341 gtactcgtac aaatcgcttg catagccgga tgctcgatct tgctacaaat attcggattg
    14401 gaagattggg aggaattctc gatcacgatt ccttttcgat tcctgttcgg cctaatggca
    14461 tggatcattc tatcccaatg gtatgccagt cgggaaagaa agagtgaggc ggaacctatc
    14521 gtgagacaaa tggaggaaaa gacggcacct cccccgacta ccgttccgga ggagattcta
    14581 gatcgtatat ccgtaaaaga cggggcacgt attcatatca tcccgataaa agagatattc
    14641 tatttgcaag catgtggcga ctatgtgacc ttattcacca cttccggtca gcacgtaaag
    14701 gagcaaacca tgaagtattt cgagcgaagc cttccttctc cggagttcgt tcgtatacac
    14761 cgctcttata tcgttaatac ggaacagata ttgcgagtag aactattcgg aaaagaaacc
    14821 tatcaagtac gattaaagga tggaacatat cttcgtgcca gtagcgctgg ctataagcta
    14881 ctcaaagaac gtctttccct ttagcagtcc tataaaaggg acctaatcat cgttaaaatt
    14941 agaagatttt gattgtaata tatagagttt tgtgttgtgt aacacttttt ggcaagcata
    15001 gatatgttac ttaacatata ttagttgcaa aagacttgac aaatggtctt gacgaacgta
    15061 tctttgcatc gtggtttttt cataatagta ttagatttaa ggttaacaaa gtttggttag
    15121 ggcttgtcgt gagacaggct ttaattgttt atagaggttt gcttccctag atttacatat
    15181 aactataaaa aaacggccac ccctaaaaag aggcggccgt aattattctt aatgaaagaa
    15241 cctactcttt gacaatcctt gtaacttcca aatcaaagat caaagtcgta taaggcttta
    15301 ttatgacact tcccgaagca ctccttccag ccgaaccgta tcccatctgt tgaggaatcc
    15361 aaatctccca acgatctcct gggtgcatat tctgtaacgc tgtagcaaaa ccatctacca
    15421 tctcagaaac agtaagttcg gcaggggcac ctgcctcaaa cgatttatca tcaaaaaccg
    15481 ttccatcaat aaacgtccct ttataataac attccacctt gctcgtataa taaatcggct
    15541 ccttactctc tcctgtcttc aagaccttgt aaaggataaa tccggcatta ctttgagaac
    15601 tcaattgctc gaaacccgga accagcatct gggcttgaaa agcctcctca ttctggacct
    15661 tccaaacctc atccacctct agtgcctcat catcatcccc acaagaggtg atcatgaaca
    15721 cgcaaaacaa catcaacgcg atatgccagt acttcttcat tcgtttactc tattaccttt
    15781 ttcaataaat tcttcatgct caccttctcc gtgataatat cgtgaagctt atcgatgctt
    15841 acgcgctctt gctccatcgt gtcacggaaa cggatcgtta cgcaattatc cttcaaggtg
    15901 tcatggtcta ccgtaataca atacggggta ccgatcgcat cctgacggcg ataacgctta
    15961 ccaatagaat ccttctcgtc gtattggcaa cggaagtcga aacgcaacat atttataatc
    16021 tcctcagctt tctcgggcag gccatctttc ttcaccaatg gcaatacggc caacttgatc
    16081 ggagccaagg ctgcgggcaa cttcaatacc acacggctct cgccattcgc caatgtctcc
    16141 tcgcagtaag aacccgccat gatgctcaag aacacacggt ctacaccgat cgaggtctcg
    16201 attacatacg gagtgtaact ctggttcaac tccggatcga aatattggat ctttttaccg
    16261 gaaaacttct catgctgact caagtcgaaa ttcgtacggc tatgtatacc ctccacttcc
    16321 ttgaatccga acggcatctc gaactcgata tccgtagcgg cgttagcgta gtgagccaac
    16381 ttctcatgat cgtgataacg atacttctga tctcccaagc caagagcttg atgccatttt
    16441 aagcgagtag acttccattt cttgaaccac tcgatctcct cacccggacg aacgaagaat
    16501 tgcatctcca tttgctcgaa ctcgcgcata cggaagataa actgacgagc cacgatctca
    16561 ttacggaacg ccttaccgat ctgggcgata ccgaacggga tcttcatacg gccagtcttc
    16621 tgcacattca agaagttcac gaaaatacct tgagccgtct ccggacgaag ataaatctta
    16681 gtcgctccat cagcggtaga acccatatcc gtagagaaca tcaagttaaa ctggcgaacc
    16741 tccgtccagt tacgagttcc ggaaatcggg caaacgatct cgcaatccaa gatcaattgg
    16801 cgaagatcct cgaagttaga ctcgttcatc gccttactat aacgctcatg aa
//
