LOCUS       c00048_gnlPro..        14449 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AOMFIFAP_48.
ACCESSION   c00048_gnlPro..
VERSION     c00048_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-08 00:18:36
            Original ID  :: gnl|Prokka|AOMFIFAP_48
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 9791
            Orig. end    :: 24240
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14449
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[19791:21301]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..11510
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14449
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14449
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             728..889
                     /locus_tag="ctg48_17"
                     /transl_table=11
                     /translation="MATAAGIAGINRSETASVAIVAGAYIVVETVAVVETDRVGSCYPV
                     GVRIVGDR"
     CDS             886..1092
                     /locus_tag="ctg48_18"
                     /transl_table=11
                     /translation="MSLGKSLKSLLTAHIRSGHLFYPYPFYRPLHKLRMQRAGIARMLT
                     GKIASYHFIGFLNLFPNNASRIV"
     CDS             complement(1183..2448)
                     /locus_tag="ctg48_19"
                     /transl_table=11
                     /translation="MKKKNYFYLAALSLAMTFSMGACSDNNDPNPDGGGKDPVNLDYSS
                     ENASAWGNYMYNVAMLLNDDATTLYNSWVTDYVDEQGSHGPYATIFKDQTAGAYQSPLS
                     CIEEMIESGMWNIANEVGDAKIKDPYTKYTSGDKEGGLYAVESWYSWHSRDDYTNNIFS
                     IRNTYYGRIDDNDVSKVDGNLSAFNSYKDFDDEGDIAEHSLSKLIASTNPDLDEEIKTL
                     IFASAKAIQAIPQPFRNNIDSEESVAAMNTCMELANLLLNEVKPYVNQTFGDPEYDDDL
                     DAIAEQFVDAIVLPTYKDLQEKNKLLLDAVNQFRQNPSNDNFEKACNLWITAREPWEKS
                     EAFLIGPVANLGLDPNMDSWPLDQNGIVQVLNSQNWDDLEWSGNFDEEDEAIGAAQSVR
                     GYHTLEYLLFKDGQPRTVDGAK"
     CDS             2476..2604
                     /locus_tag="ctg48_20"
                     /transl_table=11
                     /translation="MLFLFAEEPADVGDGQAEFVFAVIFAASDFACCIVCFHDKIR"
     CDS             2662..3060
                     /locus_tag="ctg48_21"
                     /transl_table=11
                     /translation="VLAFAFLLRVVVFVADERIDDGHVPVVFTNRTQVEPHFATIADRT
                     FGDRGCLCIRRTAALVVVDTAEVVGFAQVAVYHVCACGDIFVFVLQVGRIDAQRYVSIF
                     DVCFRFVGIGSRIVAIVEGTAYFQSRYS"
     CDS             3247..3522
                     /locus_tag="ctg48_22"
                     /transl_table=11
                     /translation="MPGRRKDGRFAFRTRSSEEVDRLMMLVGQTDRDDQMTGTDIEGRM
                     DKTCDVELFQSNFTAFFNFHFVFSVFCVFYLIGTTRTSSLKFYFCS"
     CDS             3529..3792
                     /locus_tag="ctg48_23"
                     /transl_table=11
                     /translation="LGIEFVIESQDKTGYGDRIAMVFLASVVRTPETVDAVVHKVCEDL
                     PISAEAELVISVGINVCGLFHCGFFCRCFFLFLCKCRYTRGE"
     CDS             4152..4517
                     /locus_tag="ctg48_24"
                     /transl_table=11
                     /translation="VKRGFFFMFPFPISFCPESVRRRVLDLFPQGYVCYFGCAKTITSA
                     WHNRFLGMKRSLHRHETLVGLFLLVFRADDVPQFHLVADLLFCDPSQASGDFGAVLFHT
                     EQIGGGDVRSIDFYILY"
     CDS             5104..8103
                     /locus_tag="ctg48_25"
                     /transl_table=11
                     /translation="LEKVAAPANNAAWTGGPYVLVADEDGTLEGSDLLLQAVVSEDGKT
                     VKYYGENLSAFATGAKLKEITWTFTETPVKDVAGVPNGYYYTLTSAASGKPLTVNQSGD
                     LIEKLENCKLDAANHLYTQFSVLSNDFTSRFLQGSGLYPYAGGAGLNPVSLTRAELTSI
                     VGLTGSKLYLYKLKTQELVDQVAVEAMNETMAGEGFNFDFTPKKKLDWANDVLSDVKLK
                     AFYVDNDFDLGNDMKIPAGVYFATSYPEELVGTDKIADSDLFKQCTFIAIDPTGNYDIN
                     ATDRDNGLGYELITMQGSEMNFFHGAATSDNFSHAEEVFVGNACFVVEVPNAVTAPETY
                     NIKAKNIHVFVTATDNAAKKHVAKAGLYIGCIADQNKNYMVTTVVTDALAFTTTNTTLL
                     DGDGLVGFLQEEDAPSVYTIQFVSGEKNEGASEYEQYLTVNKPAGFELASTVDFNEADP
                     MYQFVVTGVDKTNKTITLANRQTKVDFTVSLYENEDGVYTVLPATGSKDKVYVEYINGT
                     VGNNSKDEVVTFEAIDLTNMKIVLTPYTVEDKFATFVNRADNMGLVQFELALNSDIAPA
                     FYVGGEKDVDGNLAPNKDILAYADADSMVQFELIKSKKPVNVLNNYIYLDGKRIRTSTE
                     RDTVAFYTYAVKAFDDANDRYLSNTWELEVATDVSADEFIIKQNLDGSVSLIKAATTTD
                     VNGAFAMVNDLKKDRETAWKDAYNYELEHKIDKGLKTFMVDETPAVSLEAVPQHVSFAL
                     TRGGFLTNKDNDAFQSIATEASEDLTFWVDTVKSDKNIPTFYISKAGHFLYNAEDSVEY
                     YEARGNYRFNLENQKGEAAKLIFNAGELVSSDTLRTVVDGKSVLVAEKDNAPKKIKGGL
                     DNFQFQIIKAEDGSDEYVIRQGRANYVQMINSYFYLEANKNTAVRFLIESQSTPTANEG
                     VAVSEVKVLAGEGNVTIAGAAGKKVVISNILGQVVANTVISSDNAVIAAPAGVVVVAVE
                     GEAAVKAIVK"
     CDS             complement(8299..8565)
                     /locus_tag="ctg48_26"
                     /transl_table=11
                     /translation="LNCAQFSFSNFISLSCLFRFRHAKIRLFPLSEKDCKGRGMLNRRK
                     NLQIGIREIKTKPRQYEYRRGLFFVCRPVFTEGKAVELLISLL"
     CDS             complement(8690..8950)
                     /locus_tag="ctg48_27"
                     /transl_table=11
                     /translation="VRLSVFGEDLFCHRVQMITIGFQTVFDHADTAFREDTTFQRGICL
                     QADDYFVFLIDVTGSVCVNPLGKLRFGIIYSFLPFNLKHLG"
     CDS             complement(8966..9997)
                     /locus_tag="ctg48_28"
                     /transl_table=11
                     /translation="VNDLQCIDIDFCQPAHHLLVFLHHFVVVQILAGDRFETGSHLHTR
                     FLVTSAIDRIQQALCQVGTSSEILHLLTDLHWRNTAGDTVIVAIVRTHQIVVLVLDGRG
                     IDRYFCAEVFPVIRSIVEPKHRQIGFGCRAEVIQGMQITVRCLCHQRTAVNTLSAQRFS
                     HPNRVAGEQVVVFRSTQETDNTQFDNKLVDQFLCLFFRQLAFANIFFDIDIEESRSTSE
                     RHGCSILILYGCQVSQIQELHGFAGILCRTCHIETITGTHFLKCFQRFDLLRYLLTALN
                     DFFCQFLYIETFLETFLFFDQDLGSVQRYTTVITDDTSASVSIRQPGNDGGTTCRNHLV
                     CIG"
     CDS             10001..10771
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_29"
                     /sec_met_domain="Gly_radical (E-value: 3.9e-46, bitscore:
                     147.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 6.6e-46, bitscore:
                     148.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDKYAYEAFEMGLHDGDVERIRATGIAGLSIVADSLAAIRDTKV
                     KVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVDITEKFMEYLRQHQTYRKATPTQSI
                     LTITSNVVYGKKTGTTPDGRPGGTPFAPGANPMNGRDTKGAVAALASVAKLPFQHAHDG
                     ISYTFAVSPATLGKERDIQINNLVSLLDGYFTPDGGQHLNVNVFDKDLLVDAMEHPEKY
                     PQLTIRVSGYAVNFVKLTREQQLDVISRTINSSL"
     CDS             10734..11510
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.8;
                     E-value: 1.2e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_30"
                     /sec_met_domain="Radical_SAM (E-value: 1.5e-35, bitscore:
                     114.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LTSSRAPSTAVYNCPLINMLGRIHSLESFGTVDGPGIRFVVFMQG
                     CPLRCLYCHNPDTWEVKRETPYLLEPEALLAEVLRYKNFIAKGGVTVTGGEPLLQPEFL
                     KEFFRLCRENGIHTALDTSGYICSGKALEVLEQVDLVLLDIKTIDAGLHPRLTAVKLDN
                     TLRFLDELEKRGIPVWIRHVIVPGLTDDDEALSKLAEYISSYNVVQKAELLPYHTMGAY
                     KYEAQGLDYKLKGVEPLSAERLANAKAIFMKHGITV"
     CDS             11697..11834
                     /locus_tag="ctg48_31"
                     /transl_table=11
                     /translation="VELFTGFSFVRGICETHEESHALQTSNRLAENVLYKLALLIFEYF
                     "
     CDS             12095..12661
                     /locus_tag="ctg48_32"
                     /transl_table=11
                     /translation="MEPIINSQVPEFKVQAFQNGSFKTVSSEDIKGKWAIFFFYPADFT
                     FVCPTELVDMADKYGKFQEMGVEVYSVSTDSHFVHKAWHDASETIRKIKYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKIAEIHDNGIGRNADELLRKVEAAQFVASHP
                     NEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             12648..14231
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_33"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.3e-48, bitscore:
                     154.8, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVRSKVMLDSAMKDQLSGIFSGLVSQYVFDIQVAPDHESRQELID
                     LLGDVASCSDHLSCSVADGEGLQFTIVKDGMPTGIRFRAVPNGHEFTSLLLAVLNSDGK
                     GKNIPDESICARVRALNGPIKLTTYVSLTCTNCPDVVQALNVMATLNSRITHETVDGAI
                     NQKEVEAMKVQGVPSVFADGKLINVGRSDLGELLSKLEAQYGINEGGVDNSVEKPVKNY
                     DVLIVGGGPAGAASAIYSARKGLNVAVIAERIGGQVKETVGIENLISVPQTTGKQLAND
                     LLMHINDYPVDILEHRRVDKVELDGSAKLLTTSTGERFSAPALIVATGASWRKLNVPGE
                     ADYIGKGVAFCPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKAD
                     QVLQEKAKSLPNVEVFLHSQSLEVVGDGDKVTGLRVKDRKTDAERVIDLDGIFVQIGLA
                     ANSGVFRDVVETNKPGEIVIDAHCRTNVPGIYAAGDVSTVPYKQIIIAMGEGAKAALSA
                     FEDRMRGPIG"
     CDS             14260..14448
                     /locus_tag="ctg48_34"
                     /transl_table=11
                     /translation="VCKLNYTNVCSKLHTFSFLRTKPRLSQQGNRIKIFQGCDLHTKFL
                     QILYHSITTKVVAINIQA"
ORIGIN
        1 tcgcttcgta aaacttttgt tctcctaaga tgacctgagg gtcgtttatg ttgcgccgtg
       61 ccggtacgcc gaggctttgc atgtaaaggt ccacatcttc catatcggcg gtcgatatgt
      121 cgagctggtc gtacgagagt cccatcatgc tgccttggtt gatctgagcc tgcccttcgc
      181 aaatctcttc cggatagcgg ctgtttgtca cgcccatatc gcttgaaaag cccagttcga
      241 cggtcaggtc aagatgctgt gccttgtttc ctgaaaggcc gacaccggtg acacccttct
      301 cagtgatata gttgcaacgt ccgctgatgc catattccgg ataattgctt ttggcagcga
      361 gcgcttcgat ttccctgcgg tcgattgcca tcatctgtcc cataccgacg tggcgtaacg
      421 ggatgcgtac ggtgcagaac aaatcttccg gggcgatact gtctttatac cattcggtta
      481 ttgtgtaatt gggtttgcat agttcgtaag tctctccgtc ggggaaggaa aaagtctgct
      541 tgtcgtatgt gacggacaac ttaccttccg gtttgacgcc gtagatggct tggtcgtgca
      601 atacacgtcc gtagtcgcgg aagaaagcac cgttgcggcg ggagatatag accagcatgg
      661 aagagaaacc gtagttgccc gatccgccgt tttcccacaa tgtcggtttg gtccttcctg
      721 cgttgcgatg gcaactgccg caggaatagc cggcataaac aggtccgaga ccgcctccgt
      781 cgccattgtt gctggtgcgt acatcgtcgt agagaccgtc gccgttgttg aaacggatcg
      841 agttggctcc tgttatccag tcggcgttcg tatcgtaggc gaccgatgag tttaggaaaa
      901 tcgttgaagt ccctgctgac agcgcatatc cgttcgggac atctatttta tccatatcca
      961 ttttatcgtc ctcttcacaa gctgcgcatg caaagagcag gaatagcgag gatgttaaca
     1021 ggtaagattg cttcatatca ttttattggt tttctgaatt tatttccgaa taacgcgagt
     1081 cgcattgtgt aattactctg aaaccctgaa acagcgggca tttgtctgct gtttcaaggt
     1141 ttgtcatgat ctattatcaa gttttatgtc tcagaggcat gtttattttg ctccatcgac
     1201 agtgcggggc tgcccgtctt tgaacaggag atattccaat gtatggtaac cacgtacgct
     1261 ctgtgcggct ccgatggctt catcttcttc gtcaaagttt ccgctccatt ccaggtcatc
     1321 ccagttctgt gagttcaata cctgtacaat gccgttctgg tccaaaggcc agctgtccat
     1381 gttggggtcc aaacctaagt tggcgaccgg accgataagg aaagcttcgc tcttttccca
     1441 cggttcgcgt gccgtgatcc ataagttgca ggccttttcg aagttgtcgt tgcttgggtt
     1501 ctgtctgaac tggtttaccg catccagcaa aagcttgttc ttttcctgca agtctttata
     1561 agtaggaaga acgatcgcat cgacaaactg ttcggctatt gcatcaaggt catcgtcgta
     1621 ttcaggatcg ccgaatgttt ggtttacata cggttttact tcatttaaca acaggttggc
     1681 cagttccatg caagtgttca ttgcggcaac ggactcttcg ctgtcgatgt tgttgcggaa
     1741 cggttgcgga atagcctgga tcgcctttgc agaagcgaaa atcagcgttt tgatttcttc
     1801 gtcgagatcc gggttggttg aagcgatcag ttttgaaagc gagtgttctg cgatgtctcc
     1861 ttcatcgtcg aaatctttgt aagagttgaa tgcactcagg tttccgtcta ctttggacac
     1921 gtcgttgtca tcgatgcggc cgtagtatgt gttacggatg gagaagatat tgttcgtata
     1981 gtcgtcgcgc gaatgccagc tataccatga ttcgacggca taaagaccgc cttctttgtc
     2041 accgctggta tatttggtat acgggtcctt gatcttggca tcacctactt cgttggcgat
     2101 gttccacata ccgctttcga tcatttcctc gatacacgag agcgggcttt ggtaagcccc
     2161 ggcagtctgg tctttgaaga tcgtggcgta tgggccgtgt gaaccctgct catcgacgta
     2221 gtcggtcacc caggagttgt agagcgtggt tgcgtcgtca ttcagcagca tggctacgtt
     2281 atacatatag ttaccccatg cactggcgtt ttcagaactg taatccaggt tgaccggatc
     2341 ttttccgcca ccatccggat tggggtcgtt gttgtcgcta catgctccca tcgagaatgt
     2401 catggcgagc gataaggctg ccagatagaa ataatttttc tttttcattt tattgattaa
     2461 gctattaaat tgtttatgtt gtttttattt gctgaggaac cagctgatgt aggcgatggc
     2521 caagctgaat tcgttttcgc tgttatattt gccgcctccg attttgcgtg ttgtatagtc
     2581 tgctttcacg acaagattag gtaaagcata ccaattggct ccggctgtcc acatgcttac
     2641 tttgttgcgt aagtccatcg tgtgcttgcc ttcgcctttc tcctgcgggt tgtagtattc
     2701 gtagcggacg aacggataga tgacgggcac gttcctgttg tctttacaaa ccgcacgcag
     2761 gttgaacccc acttcgccac catagctgac cgcacgtttg gcgatcgggg ttgtctgtgt
     2821 ataaggagaa ccgccgcttt ggtggttgtt gacactgctg aggtcgtcgg ctttgctcag
     2881 gttgccgtat atcatgtttg cgcgtgcggt gacatatttg tttttgtatt gcaggtcggc
     2941 cgtatagatg cgcaaaggta tgtttccata tttgacgtat gtttccggtt tgtcggaatt
     3001 ggctcccgta ttgtggcaat agtagaagga accgcctatt ttcaatcccg gtactcctaa
     3061 atagttcagg cgggccacat agcccggcga ggtgaagtta tctgtttcga atagtccctg
     3121 cttgccgccg gcaacccatg tattgcggtc gaacccgttg gcgttcaatc cggcaacgac
     3181 caaagcctgg tagttgaaac gtgtgtagcc tcggccgaac gtaccgaaca cttcgatacc
     3241 gttttcatgc caggtagaag gaaggatggt cgtttcgcct tccggacgag aagttccgaa
     3301 gaagttgatc ggctcatgat gctcgttggt caaaccgacc gggacgatca aatgaccggc
     3361 acggacattg aaggccggat ggataagacg tgtgatgtgg aattgttcca aagcaacttc
     3421 accgcctttt tcaacttcca tttcgtattc tccgttttct gtgttttcta tctcataggc
     3481 actacccgta cctccagcct caaattctat ttctgctcct aatacccatt gggaattgaa
     3541 tttgtaatcg aaagccaaga caaaacgggg tatggagatc gaattgcgat ggtctttctt
     3601 gcttccgttg tccgtacccc ggaaacggtt gatgccgtag tccataaagt ttgcgaggat
     3661 ctccccatat ccgccgaagc ggaacttgtt atatccgtcg gcataaatgt ctgcggattg
     3721 ttccactgcg gatttttctg tcgttgtttc ttcttgttcc tgtgcaaatg ccgttacaca
     3781 agaggtgagt agagtgattg ctaataaatt agttaacctt ttcattgcgt tttttaattt
     3841 ttggcaaaat tagaggggct gtcaacggtg tgcaatcgca attagtaggt aaaaaggttc
     3901 cgatgttacc catttgtagg tattgcgcct gaatatcacc ttgattaggt agtaaaagac
     3961 gtttttttac tcacatatag gtattgtagg aggtgggaag tgcccgtatc tttgcaatgt
     4021 cattaagaaa gtaacactat tagtataatc gctatatcaa aaccttttgc tatttatgta
     4081 agcatataag atgattaact atatcggaaa gtttttattg gttattttcg atataaaaaa
     4141 gaagcctctc tgtgaagaga ggcttctttt ttatgtttcc gtttcccatt agcttctgtc
     4201 cggaatctgt tcggcgtcga gtcttggact tgttcccgca agggtatgtt tgctacttcg
     4261 gctgtgccaa aacaattaca tcggcttggc acaaccgttt cctcggcatg aaacggtcgt
     4321 tacataggca tgaaacactg gtcggtttgt ttctcttggt atttagggct gatgacgtgc
     4381 cacagtttca cctcgtcgcc gatctgttgt tctgcgatcc ttctcaagca agtggtgact
     4441 ttggagctgt cttgtttcat acagaacaga taggaggcgg ggatgtcaga agcatcgatt
     4501 tttatatatt atattaatgt attatagttg tttgatccgt ctgtaacgga cgttgatgta
     4561 aagatacata ataatgtaag gttttgcaag tcttgaaacc gttattgagc aagcaatcga
     4621 tatctccgta ttttgtatat ctttaacaaa aggggacgct tctccaagag gaaattacga
     4681 aaccagttgt ttttgccatt ttttcttccg atgcgagtaa aggatgtttg tcttgtatgt
     4741 ggctgataat ctttgtttta atgaagatgt aaagaggttt ggcgaatgat tgaaaacagt
     4801 tacttttata tatggcttta gctacttttg ggtgctataa attgttgtta ataagaagta
     4861 taggtgtatg agaagaaaaa tggtgaaaaa acgtacgttt tatctcgtca aaatacagga
     4921 atttggtaaa aacctgttaa acaggaagta agaacgatat tcaatataca tattattatt
     4981 aattaaacat tttagattat gaacaagaag ttttctactc ttttgacaat gggcttgttg
     5041 gctacaagtt cgttgtgtgg tagtgcttgg gcgcagactg ctcctacaat taatgggatt
     5101 gaattggaga aggttgctgc tcctgccaat aatgctgcat ggacgggcgg tccttatgtg
     5161 ctggttgctg atgaggatgg tacgcttgaa ggctctgatc ttttgctgca agcagtagtt
     5221 agtgaggatg gtaaaactgt aaagtactat ggtgaaaatc tttcagcttt cgcaactggt
     5281 gctaagttga aagagattac ttggactttt actgaaacac ccgtgaaaga tgttgctggt
     5341 gtacctaatg gctattatta cactttgact agcgctgctt ctggtaagcc gttgacagta
     5401 aatcaatcag gagatcttat agaaaaatta gaaaattgta aacttgatgc ggctaatcat
     5461 ttgtatactc aattctcagt gctgtctaat gattttacaa gccgcttttt gcaaggttca
     5521 ggattgtatc cctatgcagg aggggcaggg ttgaatcctg tttcattgac acgtgcagaa
     5581 cttacctcta ttgtaggttt aactggaagc aagttgtatc tctacaaact taaaacccag
     5641 gaattggttg accaagtagc tgttgaagcc atgaacgaga ctatggctgg cgaaggtttt
     5701 aacttcgatt tcactcctaa aaagaaattg gattgggcaa acgatgttct gtctgatgtg
     5761 aaattgaaag cgttttatgt tgataacgat tttgacctag gtaacgacat gaagattccc
     5821 gcaggtgttt actttgctac ttcttatccg gaagaattgg tcggaacaga taagattgct
     5881 gattcggatc tgttcaaaca gtgcacgttc attgctatcg acccgacagg caactatgac
     5941 atcaacgcga ctgaccgtga taatggctta ggttacgaac tgataactat gcagggtagt
     6001 gaaatgaact ttttccatgg tgctgctaca tctgacaact tctctcatgc agaagaggta
     6061 ttcgtaggca atgcttgttt cgtagttgaa gttcctaatg cagtgactgc tccggaaaca
     6121 tacaatatca aagccaagaa tattcacgtg tttgttactg caacagacaa tgcagctaaa
     6181 aagcacgtcg ccaaggctgg tctttatatt ggttgtatcg ctgatcagaa taagaactac
     6241 atggtaacta ctgttgttac tgatgctttg gctttcacta cgactaatac tactctgttg
     6301 gatggtgatg gtttagttgg cttcttgcag gaagaagatg caccatctgt ttacacaatc
     6361 cagtttgtaa gcggtgaaaa gaatgaaggt gcttctgagt atgaacaata tctgactgtg
     6421 aataaaccgg ctggtttcga attagcttct actgttgatt tcaacgaagc agacccgatg
     6481 taccagtttg ttgtaacagg tgttgacaag acaaacaaga caatcacttt ggctaaccgt
     6541 caaacaaaag ttgatttcac tgtttcgctg tatgaaaacg aagatggtgt atatacagta
     6601 cttccggcaa caggcagcaa ggataaggta tatgtagaat atatcaatgg tacagttgga
     6661 aataattcaa aggatgaagt cgttactttt gaagctattg acttgacgaa catgaagatc
     6721 gtcctgactc cgtacactgt agaagacaag ttcgctacat tcgtgaacag agctgacaac
     6781 atgggcttgg ttcagttcga attggccctt aacagcgata tcgctccggc attctatgtt
     6841 ggtggcgaga aagacgtaga tggcaatctg gcaccaaaca aagacatctt ggcttatgcc
     6901 gatgcagaca gcatggttca gtttgaactg attaagagca aaaagccggt taatgtattg
     6961 aacaattaca tctacttgga tggcaaacgt attcggactt caacagaaag agacacagtc
     7021 gctttctata cttatgcggt taaggcgttt gatgatgcaa acgacagata tctgagcaac
     7081 acttgggaac ttgaagtagc aacagatgtg tctgcagatg aattcatcat caagcagaat
     7141 ttggatggtt ccgtatcatt gatcaaagct gcgactacaa ctgatgttaa tggagctttc
     7201 gcaatggtta atgacttaaa gaaagacaga gaaactgctt ggaaagatgc atacaactac
     7261 gagttggagc ataagatcga caaaggcctg aagaccttca tggttgacga aactccggct
     7321 gtcagcctag aagctgttcc gcagcacgta tctttcgcac tgactcgtgg cggtttcttg
     7381 acgaacaagg acaacgatgc gttccagagc atcgcgacgg aagcaagtga agacttgaca
     7441 ttctgggtag acacagttaa atctgacaag aatattccta cgttctacat ttctaaggct
     7501 ggtcacttct tatacaatgc agaagactct gttgagtatt acgaagctcg tggcaactac
     7561 cgcttcaact tggaaaacca gaaaggtgaa gctgctaagc tgatcttcaa tgctggtgaa
     7621 ttggtctctt ccgacacatt gcgcactgtc gttgacggaa aatctgtcct ggtagcagaa
     7681 aaagacaatg ctccgaagaa aatcaaaggc ggtttggaca acttccagtt ccagatcatc
     7741 aaggctgaag atggtagcga tgaatatgtg atccgtcagg gtcgtgcaaa ctatgttcag
     7801 atgatcaata gctacttcta tctggaagca aacaagaaca cggctgttcg cttcctgatc
     7861 gaatcccagt ctactccgac agccaacgaa ggcgtagccg tatctgaagt gaaagttctc
     7921 gccggcgaag gcaatgtgac aatcgcaggt gctgccggca agaaggttgt catcagcaac
     7981 atcttgggtc aggtagtagc aaacacagta atctcttctg acaacgctgt aatcgctgct
     8041 ccggcaggcg tagtagttgt agctgttgaa ggcgaagctg ctgtaaaagc tatcgttaag
     8101 taacgattga tactaaaaaa acaatactgt ctatcgtaag ggtggttagt gaaccaccct
     8161 tacacaggca caatgacatt ttataatcaa ataattctag acaacctgcg tgaaaccgta
     8221 tgtaagaggt tttcttgatc tacggtttca attaccctgc gacaggcgaa cgagcggttg
     8281 gatttaatat taataatact aaagtaatga aattaaaagt tctactgctt ttccctctgt
     8341 gaagaccgga cggcagacaa aaaacaggcc tcggcggtat tcgtactgcc ggggcttcgt
     8401 ttttatttcc cttatcccta tttgtaggtt ttttctccgg tttaacatcc ctcgtccttt
     8461 acaatccttt tcagataggg ggaaaagacg tatctttgcg tgcctaaacc gaaatagaca
     8521 agataagctt atgaagtttg aaaacgagaa ctgggcgcag ttcaaaggag aaacctggaa
     8581 aaaggagatc aatgtaagag actttatcca gaacaattac aaaccttata acggagacga
     8641 tacgttcctc gtaccctctt cggagaaaac gaagaaagtg tggaacaaac taaccgagat
     8701 gtttaaggtt gaaagggaga aaggagtata tgatgccgaa acgaagcttc cccaggggat
     8761 tgacacatac ggacccggtt acatcgataa ggaaaacgaa gtaatcgtcg gcttgcagac
     8821 agatgccccg ttgaaacgtg gtatcttccc gaaaggcggt atccgcatgg tcgaaaacag
     8881 tctggaagcc tatggttatc atctggaccc gatgacaaaa gagatcttca ccaaatacag
     8941 aaagacgcac aacgaaggcg ttttttcagc ctatacagac gagatgattg cggcacgtcg
     9001 ttccgccatc attaccgggt tgcctgatgc ttacggacgc ggacgtatca tcggtgatta
     9061 ccgtcgtgta cctctgtacg gaacccagat cctgatcgaa gaaaagaaac gtttccaaaa
     9121 acgtctcgat atacaggaac tgacagaaga aatcattcag agccgtgagg agataacgga
     9181 gcagatcaaa gcgctgaaag catttgagaa aatgtgtgcc ggttatggtt tcgatgtgac
     9241 acgtccggca aaggatgccc gcgaagccgt gcagttcttg tatctggctt acctggcagc
     9301 cgtaaaggat caggatggag cagccatgtc tctcggacgt acttctactt tcctcgatat
     9361 ctatatcgaa aaagatattt gcgaaggcaa gctgacggaa gaagaggcac aggaattgat
     9421 cgaccagttt attatcaaac tgcgtattgt ccgtttcctg cgtactccgg aatacaacga
     9481 cctgttctcc ggcgaccctg tttgggtgac tgaatcgctg ggcggacaag gtgttgacgg
     9541 ccgttcgctg gtgacaaaga catcttaccg ttatctgcat accttgtata acctcggccc
     9601 ggcacccgaa cccaatctga cggtgctttg gttcaacaat gctccggata actggaaaaa
     9661 cttctgcgca aaagtatcga tcgatacctc tgccatccag tacgagaacg acgatctgat
     9721 gcgtccggac tatggcgacg attacggtat cgcctgctgt gtttctccaa tgaagatcgg
     9781 taagcagatg cagtatttcg gagctcgtgc caacctggca aagtgcttgt tgtatgcgat
     9841 caatggcgga cgtgacgaga aatcgggtgt gcaggtggct ccccgtttcg aaccgatcac
     9901 cagcgagtat ctggactaca acgaagtgat ggagaaatac gagcagatga tgcgctggtt
     9961 ggcaaaagtc tatgtcaatg cactgaagat cattcactac atgcacgaca aatatgcgta
    10021 tgaagcattc gagatggggc ttcatgacgg agatgtggaa cgtatccgcg caaccggtat
    10081 cgccggcctt tctatcgttg ccgactcgct ggctgccatc cgtgacacga aagtgaaagt
    10141 gatccgtgac gaacgtggtt tggctgtcga cttcgaacgc gaaggcgaat atgtaccttt
    10201 cggaaacaat gacgaccgca cggacagtat tgctgtcgac attactgaga agtttatgga
    10261 atatctgcgc cagcatcaga cataccgcaa ggcaactccg acacaatcta tcctgacgat
    10321 cacatcaaac gtggtctacg gaaagaaaac cggaacgact cccgacggcc gtccgggcgg
    10381 tacgccgttt gctccgggag ccaacccgat gaacggacgc gatacgaaag gggctgtcgc
    10441 cgctttggct tctgtcgcca aactgccttt tcagcatgcg catgacggta tttcctatac
    10501 attcgccgtt tcaccggcta cgttgggtaa ggagcgcgat attcagataa ataacctggt
    10561 gagcctgttg gatggctatt tcacgcctga cggcggccag catctgaatg tgaacgtgtt
    10621 cgataaggac ctgttggtcg atgcgatgga gcacccggag aaatacccac agcttacgat
    10681 ccgtgtttcg ggctatgccg tcaacttcgt gaagctgaca cgcgaacagc agcttgacgt
    10741 catctcgcgc accatcaaca gcagtttata attgtccatt gattaatatg ttggggcgta
    10801 tacattcttt agagagtttc gggaccgttg acggtcccgg aattcgcttt gttgttttca
    10861 tgcagggatg tccgcttcgt tgtctgtatt gccacaatcc ggatacctgg gaggtaaagc
    10921 gtgaaacgcc ttatctgctg gaacctgaag cgttgcttgc cgaagtgctg cgctataaga
    10981 attttatcgc taaaggtggt gttaccgtga ccggtggcga gcctttgtta caacctgaat
    11041 tccttaaaga gtttttccgc ctttgccgtg agaacggtat tcatacggcg ttggacactt
    11101 ccggctatat ctgttccggt aaagcattgg aggtgctcga acaggtcgat ctggttctgt
    11161 tagatatcaa gacgatcgac gccggtcttc atccccgttt gacggccgta aaactcgata
    11221 atactttacg ctttcttgat gaactggaga aacgcggcat ccctgtatgg attcgccacg
    11281 tgatcgtgcc cggcctgacg gacgatgatg aagccttgag caagctggcc gaatatatca
    11341 gttcatataa cgtggtccag aaagccgaac ttctgcctta tcatacaatg ggagcttaca
    11401 aatatgaggc acaaggcctg gactataagc tgaaaggtgt ggaaccgctt tcagcagagc
    11461 gtctggccaa tgcgaaagcg atctttatga aacacgggat aaccgtataa gcctaatcga
    11521 gtgtctgctc tttgatgatg atcggtttac ggctgatccg gttgactgtg cggacactgt
    11581 cgctttcaat actggtaaca tctccctcgc agttggtgaa atagatgtaa tgtcccatat
    11641 ccatgaaacg atagacctta cacccttcgt gttcgaacag atattcgact tgataagtgg
    11701 aattgtttac cggtttttcc tttgtaaggg gtatttgtga gacacatgaa gaaagccatg
    11761 cgctgcaaac gagcaataga cttgctgaaa atgtattata caaactagct cttctcatct
    11821 tcgaatattt ttaagttaac atccaaaggt aacaattaaa gaatcacatg gtatgaccga
    11881 aaggtatttt acctacaatt aggtatattt ttattgttcc ggaaaacatt actttgcttc
    11941 ctattgtcat agtagataag tatgcttgca gatagaagtc cgtctatcgg cagataaaaa
    12001 ttatcaattt gaaaaattct ttcaatcagt atcttacgat ttacctttgt agggtaaaca
    12061 aaaaatagta gtaacaaatt aaatagtaaa aatcatggaa ccaattatca attcacaagt
    12121 acccgaattc aaagtacagg cttttcagaa tggtagtttc aagacagtaa gtagcgaaga
    12181 tatcaagggc aaatgggcca tctttttctt ctatcctgcc gactttacgt tcgtatgtcc
    12241 gaccgaattg gtcgatatgg ctgacaagta cggcaaattt caggaaatgg gtgtcgaagt
    12301 atattccgta agtacagact cgcactttgt acacaaagca tggcatgatg cttccgaaac
    12361 gatccgtaag atcaaatatc cgatgctggc agacccgaca ggggctttaa gtcgtgcgtt
    12421 cggtgtgatg attgaagaag agggtatggc ttatcgcggt acgttcctgg taaatcccga
    12481 gggaaagatc aagattgccg aaatccacga taacggtatc ggccgtaatg cagacgaatt
    12541 gcttcgtaaa gttgaagctg cccagttcgt tgcttctcac ccgaacgaag tttgtcctgc
    12601 aaagtggaaa aaaggcgaag caaccttgaa gccgagcatc gacttggttg gtaagatcta
    12661 aagttatgtt agactcagca atgaaagacc agctttcggg tattttctcc ggactggtat
    12721 ctcaatatgt atttgatata caagtcgctc ccgatcacga aagccgtcag gagctaatag
    12781 acctgcttgg tgatgtggca tcatgctcgg atcatttgtc atgcagcgtt gcggatggcg
    12841 aaggacttca gtttacaatc gtaaaagacg gtatgcctac cggtatccgg tttcgtgcag
    12901 tacctaacgg acatgagttt acatccttgt tgttagctgt cctgaatagt gatggaaaag
    12961 gtaaaaatat accggacgaa agtatctgtg cccgtgtcag agctttgaac ggcccgatca
    13021 agctgacgac ttatgtttct cttacttgca ccaattgtcc ggatgtagtg caggcactca
    13081 atgtcatggc tactctcaat agccggatca cccacgaaac ggtggatggc gctatcaacc
    13141 aaaaagaagt tgaggcaatg aaagtacagg gagtcccttc tgtttttgcc gatggcaaac
    13201 tgatcaatgt ggggcgtagt gatttgggag aattgctttc caaactcgaa gcccaatacg
    13261 gaattaatga agggggtgtt gataactctg ttgaaaaacc tgttaagaac tatgatgtgt
    13321 taatagtggg gggtggacct gccggtgcag cttctgctat ctactcggca cgtaaaggct
    13381 tgaatgtcgc agtgatagcc gaacgtatcg gaggacaggt caaagaaacg gtcggtatcg
    13441 agaacctgat ttccgttcct cagactactg gaaagcagtt ggcgaacgac cttctgatgc
    13501 acatcaacga ctatccggtc gatatactgg agcatcgccg tgtggataaa gtcgaactgg
    13561 atggatcggc gaaacttctg accacttcta ccggtgaacg tttttctgct cctgccctta
    13621 tcgtggcgac aggtgcaagc tggcgcaagt tgaatgttcc gggcgaagcg gactatatcg
    13681 gaaaaggtgt cgctttttgc cctcactgcg atggtccgtt ctataaaggt aagcacgtag
    13741 cggttgtcgg cggtggaaat tcgggtatcg aagcggctat agatttggca ggcatttgtt
    13801 cgaaagtgac ggttctggaa tttatggacg agctaaaagc cgatcaagtg ttgcaggaaa
    13861 aagcaaagag cttgccgaat gtagaagttt tcttgcattc ccaatctttg gaagtggttg
    13921 gtgacggtga taaggtaaca ggtcttcgtg taaaagaccg taagacggat gcggagcggg
    13981 tgatcgacct ggacggaatc tttgtccaaa tcggcttggc agccaatagt ggcgttttcc
    14041 gcgacgttgt cgaaacgaac aaaccgggtg agattgtaat cgatgcgcat tgtcggacga
    14101 atgttcccgg catctatgcg gcgggcgacg tctcgaccgt accctataaa cagataatca
    14161 tagcaatggg agaaggggca aaagcggctc tatctgcttt tgaagaccgc atgagaggtc
    14221 caatcggtta atatttagta tttgctatga acgacgaagg tgtgcaaatt gaactacacg
    14281 aatgtgtgtt caaaattgca caccttttct tttttacgca caaaaccccg actttcacaa
    14341 cagggcaacc gcatcaaaat tttccaaggt tgtgatctcc atacgaagtt tctacaaatc
    14401 ctctatcact ctatcactac gaaggttgta gctattaata ttcaagcgt
//
