LOCUS       gnlProkkaFPJGKBHH_7    10796 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FPJGKBHH_7.
ACCESSION   gnlProkkaFPJGKBHH_7
VERSION     gnlProkkaFPJGKBHH_7
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 12:28:05
            Original ID  :: gnl|Prokka|FPJGKBHH_7
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10796
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..582)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_1"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 3.4e-31,
                     bitscore: 99.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.4e-07, bitscore: 23.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5e-15, bitscore: 48.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHQYQLNGYNIVLDTCSGSVHVVDEVAYDVIAMYPEHTADEIVA
                     AMLAKYGSRPDVTEEDLRQCIDDVTSLKENGKLWSPDVYKDMAFDFKNRNTVVKALCLH
                     VAHSCNLSCSYCFASQGRYHGDRALMSFEVGKRAMDFLIENSGTRRNLEVDFFGGEPLM
                     NFEMVKKLVAYCREQEKIHNKNFRFTMTTNG"
     protocluster    1..10796
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[0:796]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..796
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..10796
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10796
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(650..796)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_2"
                     /sec_met_domain="TIGR03973 (E-value: 7.2e-26, bitscore:
                     82.1, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 4.1e-25, bitscore: 79.7,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERIKTIATRDLTKSVKTGGCGECQTSCQSACKTSCGVANQQCEN
                     SNK"
     CDS             complement(1093..1380)
                     /locus_tag="ctg7_3"
                     /transl_table=11
                     /translation="MPERTTQNAQTLLSPRVPRDTEHERYHPELEEELKECLFCLKRNE
                     MMFDMEVDTDLIEQRIYERQALLCRYRYLLARARELGLHTVLTRYQPMGG"
     CDS             complement(1817..3577)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283:2`,3`-cyclic-nucleotide 2`-phosphodiesterase
                     (Score: 253.3; E-value: 8.5e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_4"
                     /transl_table=11
                     /translation="MKQLISRRSFLKAAGVTAAAASMAIGAPAASACWYGDKSDVTILY
                     TNDVHTYIDKQSPKLTYAAIADLKQSYQNAGKDVLLVDAGDHVQGTAYGSMDEGASIIK
                     LMNAAGYDVATPGNHEFDYGMDRAKAIMKEADFPYLSCNWVDLRTTLRVLPSVKVFVRG
                     GRRIAFVGVTTPETFTKSTPAYFMDKAQRKYIYDIQGGEDGKKLYDAVQKAIDKAKLLA
                     DVVIGLGHLGVDPSSSPWTSEEVIAHTSGFDAFIDGHSHTVMENKQVQDASGKAVTLTQ
                     TGSYFANVGEMTIAADGTITTKLIPTHEGMDAGIAAMQTGWVNTVDDMLGEKIAVGDSD
                     FYVSDPATGKRRIRSAETNLGDFVADGIYTYFNEVEKLHCDVAIMNGGGIRADVPAGDW
                     TFKTCKQVSPFGNVACLMSVTGKQIQDALEFAARFAGEDGKENGGFLQVAGATYEIHTD
                     IPNTVQTDEKNVWIGSATGTPRVQNVKIYDKASGSYLPLDPGATYALAGMNYTLRNLGD
                     GFAMFDGAELIKDYVSEDYLVMSTYAMIFDGADAAGLPHLSSANSPLAAYPGYLLNYEQ
                     PYGAGRITIL"
     CDS             complement(3855..5627)
                     /locus_tag="ctg7_5"
                     /transl_table=11
                     /translation="MYYSSGNYEAFAHPKKPEGVDHKSAYIIGSGLAALTAACYLVRDG
                     QMKGEHVHVFEKNALAGGACDGYKYDIGYVMRGGREMDNHFEVMWDLLHSIPSLETEGA
                     SVLDEYYWLNKEDPNFSLCRATVNRGEDAHTDGKFGLSDKGAMEIMKLFFTPDEQLQDK
                     KITDFFDDEVLNTNFWMYWRTMFAFENWHSALEMKLYLKRYIHHIGGLPDFTALRFTRY
                     NQYESIILPMVRYLEGFGVQFHYNTKVTDVKFDIQKGRKLASSVTVEHEGETTNIDLTE
                     NDLLFITNGGCVESCTVGAQDKATGFDPTIQPGNGWDLWKKIAAQDPSFGHPEKFCSEP
                     ELSNWESATITTLDDKIPQYIRKICKRDPFSGHTVTGGIVTVKDSSWLLSWTLNRQQQF
                     KDQPKNQLCVWVYGLFSDKPGDYVKKPMRDCTGREICMEWLYHIGVPEDQIAELAEHSA
                     NTVPVMMPYIDAFFMPRAMGDRPDVVPEGAVNFAFLGQFAETARDTIFTTEYSMRTGME
                     AVYTLLNIDRGVPEVWGSTYDVRALIDATVKLRDGKKITDMDLPLIPRLALKEALKKIE
                     GTDLEKFLKEYNAI"
     CDS             complement(5995..6258)
                     /locus_tag="ctg7_6"
                     /transl_table=11
                     /translation="MSKEFSFPNKGTCSKQTNFVLNDDHTIASIEVVGGCNGNLKGICQ
                     LLTGMKAEDAIARLDGTLCGFRSTSCPDQIAKNLKKALEEMN"
     CDS             complement(6264..7124)
                     /locus_tag="ctg7_7"
                     /transl_table=11
                     /translation="MSCDLHIHSTCSDGAVPIERLAPIAARTGLHAIALSDHDTLLSAQ
                     YAYAHTGQDGVELIPAVELTGYDFERQHRVHLLCYYPDIDCPALREHCAIMKERRNACA
                     LQSAKELEQLYPQFTTDLAWETTKASGVLFKSGLMQALELLGLTDGSIYGETYHKLFGW
                     NPRGIVLHSPEYLPVRQVLATAKASGGAVVFAHPTVYKSMPLLRELAAEGAVDGIEVYH
                     PSNSPEDSAECLALCKQYGLVATAGTDFHGRNHKHPHPIGTCTAPDEAAAQLRAIAEKR
                     KRERT"
     CDS             complement(7139..9415)
                     /locus_tag="ctg7_8"
                     /transl_table=11
                     /translation="MLDMIKCSTGGAYYARGEWVPADGNAPAALAAKGFDAAAVAAAKT
                     GTMAYNIMQAHNTSGDAENLKIKFDAMASHDITFVGIIQTARASGLEKFPIPYVLTNCH
                     NSLCAVGGTINEDDHRFGLSAAKKYGGIFVPPHMAVIHQYMRERFAGCGKMILGSDSHT
                     RYGALGTMAIGEGGGELAKQLLGRTYDVARPGVVAIYLTGSLPAGCGPHDVAIALVGKL
                     FKSGYVKNKVMEFVGPGIASLRQDTRNAIDAMTTETTCLSSIWETDEVTQRFLAVHGRA
                     ADYKKLAPADLAYYDGVVEVDLSAIRPMIALPMHPSNAFTIEELNANLEDILHACEQDV
                     QKLIGRKDVQLDLCSKIENGKLRVDQGVIAGCAGGLYDSIYEAASILKGHTGGCGDYAL
                     SVYPGSQPIMMELVRTGVIGELMASGATIRTAFCGPCFGAGDVPANGALSIRHTTRNFP
                     SREGSKPGSGQLAGVALMDARSIAATTANGGILTPATDIDYDPTVPEYQYDASSYDTRV
                     YQGFGKGDYDALLKFGPNIKDWPEIAPLGDNLLLKVASYITDPVTTTDELIPSGETSSY
                     RSNPLGLAEFTLSRKDPEYVSRAKAVQAEEAARRAGAGDAALLAKVNAVPGCEKLSWND
                     IQIASTIFAVKPGDGSAREQAASCQRVLGAGANIVTEYATKRYRSNLINWGMLPLQLAG
                     ATPFGLGDYVLIPNVREALKGDLQSIKAYVLGDTVKEFELYMAPLTTDERQILADGCLI
                     NFYKH"
ORIGIN
        1 accgttggtg gtcatggtaa agcggaagtt cttgttatgg atcttttcct gctcacggca
       61 gtaggccacc agctttttga ccatctcaaa gttcatcagc ggctcgccgc caaagaagtc
      121 cacttccaga ttgcggcggg tgccgctgtt ctcgatgagg aagtccatgg cgcgcttgcc
      181 cacctcaaag ctcatcaggg cgcggtcgcc gtggtagcgc ccctgcgagg caaagcagta
      241 agagcagctc agattgcagc tatgggcaac gtgcaggcac agagccttta ccacggtgtt
      301 gcggttcttg aagtcaaaag ccatgtcctt atagacatcc gggctccaca gcttgccgtt
      361 ttccttcagg ctggtcacgt cgtcgatgca ctggcgcaga tcctcctcgg tcacgtccgg
      421 gcggctgccg tattttgcca gcatggcggc aacgatctcg tctgcggtat gctccgggta
      481 catggcgatg acatcgtagg ccacctcgtc cacaacgtgc accgagccgc tgcaggtgtc
      541 cagcacgatg ttataaccgt tcaattgata ctgatgtacc attttacact ccattccaga
      601 ttacacaaaa aaatgccgcc cggcaaaggc ggcatagggt ttgcaaaaat tacttgttgc
      661 tgttctcgca ctgctggtta gccacgccgc aggaggtctt gcaggcggac tggcaggaag
      721 tctggcactc gccgcagcca ccggtcttaa cgctcttggt caggtcacga gtagcaatag
      781 tcttaatacg ctccatgata gaaacctctc taactctcaa aaatttatcg cgccggacat
      841 agttccggta cgcttttatc ttgtaatagg atatcacgca gcgcgccttt tgtcaagatt
      901 ttttcgctaa ggcaataccg cataattcta ggtgccgata cggcgagtga ggtgcggcag
      961 atgctaagcc aaaagcgcag ataatacttt gtgtattatc gagcattttg gcaacgcaga
     1021 tgccgtgccg caaccgccgg agtggtgctt aagccgtaag gcgggaattg tgcggtgttg
     1081 ccctaagcct tttcacccgc ccatgggctg gtagcgggta agcaccgtgt gcagccccag
     1141 ctcccgggcg cgcgccagta agtaccggta acgacacagc agcgcctgcc gctcgtagat
     1201 gcgctgctcg atcaggtccg tatccacctc catatcaaac atcatctcgt tgcgcttcaa
     1261 acagaacagg cattccttca gctcctcctc cagttccgga tggtagcgct cgtgctcggt
     1321 atcccgcggg acgcggggcg aaagcaaggt ctgggcgttt tgtgtggttc gttccggcat
     1381 aggcatcctc cttctggtgc tttgtaaggt tttgtacctt ccagtatagg cggtgcggtg
     1441 cgcagaacct gccgaagcgt ggcagcgctc tggcatagat tatccggcgc tgctgcggca
     1501 ttttccaaaa aagtacaact tttttcaaaa atatgcttga caactccggg cttttcccgt
     1561 ataatagcac acgttgagcg gctcaccccg caaaacacaa cagaatattg gggatttgca
     1621 tagtggtagt gcggtagact ctgactctac ttgtgggagt tcgattctct catccccaac
     1681 cagaacaaag ccatctgagg aagctcaggt ggcttttctg attatatcat tccgcgcgga
     1741 aaaactatta tagatagagc gaacccggaa agtccgcagg actttccggg ttcgcctttt
     1801 cacgggaaat ataaatttac agaatggtga tgcggcctgc gccgtagggc tgctcgtagt
     1861 tgagcaggta gccggggtat gcggccagcg ggctgttggc gctggacagg tgcggcagac
     1921 ccgcagcatc tgcgccgtca aaaatcatag cgtaggtaga catcaccaga taatcctcgg
     1981 acacatagtc cttgatcagc tctgcgccgt caaacatggc aaagccatcg cccagattgc
     2041 gcagggtgta gttcatgccg gccagtgcgt aagtagcgcc cgggtccagc ggcagatagc
     2101 tgccggaagc cttatcgtag atcttcacgt tctgcacgcg cggggtgccg gtggcgctgc
     2161 cgatccagac attcttctcg tcggtctgca cagtgttggg gatatcggtg tggatctcgt
     2221 aggtagcacc ggccacctgc aggaagccac cgttctcctt gccgtcctcg cctgcaaagc
     2281 gggctgcaaa ctccaatgcg tcctggatct gcttgccagt gaccgacatc aggcaggcca
     2341 cgttgccaaa ggggctgacc tgcttgcagg tcttgaaggt ccagtcgcct gcgggcacat
     2401 cggcgcggat gccgccgcca ttcatgatgg ccacatcaca gtgcagcttt tccacctcgt
     2461 tgaagtaggt gtagatgccg tcagccacaa agtcgccgag gtttgtctcg gcagagcgga
     2521 tgcggcgctt gccggtggcg gggtcagaga cgtagaaatc gctgtcgccc acagcgatct
     2581 tctcgcccag catatcgtcc acggtgttca cccagccagt ctgcatggcg gcgatgcctg
     2641 cgtccatgcc ctcgtgggtg gggatgagct tggtggtaat ggtgccgtcc gcagcgatgg
     2701 tcatctcgcc aacgtttgca aagtaagagc cggtctgggt cagggtgaca gccttgccgg
     2761 aagcatcctg cacctgcttg ttctccatta cggtatggga gtggccatcg ataaaggcgt
     2821 caaagccgct ggtgtgggca atgacttcct cactggtcca cggagaggaa gaggggtcta
     2881 cgcccagatg acccagaccg atgaccacgt ctgccagaag ctttgcctta tcaatggcct
     2941 tctgcacggc atcgtagagc tttttgccgt cctcgccgcc ctgaatatcg tagatgtact
     3001 tgcgctgtgc cttatccata aagtaggccg gggtggactt ggtaaaggtt tcgggggtgg
     3061 tcacgcccac aaaggcaatg cgtctgccgc cgcgcacgaa caccttgacg gagggcagca
     3121 cacgcagcgt agtgcgcagg tctacccagt tgcaggacag gtacgggaag tcggcttcct
     3181 tcatgatggc cttggcacgg tccatgccgt agtcaaactc gtggttgccg ggggtggcga
     3241 catcgtaacc ggcagcgttc atcagcttga tgatggaagc accctcgtcc atggagccgt
     3301 aggcagtgcc ctgcacatgg tcgcctgcat ccaccagcag cacatccttg ccggcattct
     3361 gatagctctg cttcaggtcg gcaatggcag cgtaggtcag cttggggctc tgcttgtcga
     3421 tgtaggtatg gacatcgttg gtgtacagga tggtaacgtc agacttgtca ccataccagc
     3481 aggccgatgc ggcaggcgca ccgatggcca tggatgcagc ggcagcggtc acaccagcag
     3541 cctttaaaaa gctgcgacgg gaaataagtt gtttcacagg aaaacgacct ccttttattt
     3601 ttggcgtatc gcatttgagg caggctcttc cctcctgccc tttcaatagc tctagcatag
     3661 cacagaacgc cgccgcaaac aagccaaaat cattcttttg gcacaaatta ttttcacgtt
     3721 ccgctttatt ttgacgcata ttgtaccatt tttacacaaa aaagacctcc ccgtgccctg
     3781 tcgcagagca gcggagaggt cttttttagg ggggtgttga cccgttgccg ggtctatcgg
     3841 aggagaggga aatatcagat ggcgttatac tccttgagga acttctcaag gtcggtgccc
     3901 tcgatcttct tcaaggcttc cttcaaagcc agacgcggga tcagcggcag atccatgtcg
     3961 gtgatcttct tgccgtcgcg cagcttcacg gtggcatcga tcagggcgcg cacatcgtag
     4021 gtgctgcccc aaacctcggg cacgccgcgg tcaatgttca gcagggtgta cacggcctcc
     4081 ataccggtgc gcatggaata ctcggtggta aagatggtgt cgcgggcagt ctcggcaaac
     4141 tgaccgagga aggcaaagtt cactgcgccc tcgggcacaa catcggggcg gtcgcccatg
     4201 gcgcggggca tgaagaaggc gtcgatatag ggcatcatca caggcacggt gttggcgctg
     4261 tgctctgcca gttccgcgat ctgatcctcc ggcacgccaa tgtggtacag ccactccatg
     4321 cagatctcgc ggccagtgca gtcacgcatg ggctttttga cgtaatcgcc gggcttatcg
     4381 ctgaacaggc cgtacaccca gacgcacagc tggttcttgg gctgatcctt gaactgctgc
     4441 tgacggttca gcgtccagct gagcagccag ctggagtcct tgacggtgac gatgccgccg
     4501 gtgacggtgt ggccgctgaa ggggtcacgc ttgcagatct tgcggatata ctgagggatc
     4561 ttgtcgtcca gcgtggtgat ggtggcactc tcccagttgc tcagttccgg ctcggagcag
     4621 aacttttccg ggtgaccgaa ggagggatct tgtgcggcga tcttcttcca cagatcccag
     4681 ccgttgccgg gctggatggt gggatcaaag ccggtggcct tatcctgtgc acccacggtg
     4741 cagctttcca cacagccgcc gttggtgatg aacagcagat cgttctcggt caggtcgatg
     4801 ttggtggtct cgccctcgtg ctccacggtg acggagcttg ccagcttgcg gcccttctgg
     4861 atatcgaact tcacatccgt gaccttggtg ttgtagtgga actgcacgcc aaagccttcc
     4921 agatagcgca ccatgggcag gatgatggac tcgtactgat tatagcgggt aaagcgcagg
     4981 gcggtaaagt ccggcagacc gccgatgtgg tggatatagc gcttgaggta caacttcatc
     5041 tccagagcgc tgtgccagtt ctcgaaggcg aacatggtgc gccagtacat ccagaagttg
     5101 gtgttgagca cctcgtcatc aaagaaatcg gtgatctttt tatcctgcag ctgctcgtcc
     5161 ggggtaaaga acagcttcat gatctccatg gcgcccttat cggacaagcc gaacttgcca
     5221 tcggtgtggg catcctcgcc gcggttgacg gtggcacggc acagggagaa gttggggtcc
     5281 tccttgttca gccagtagta ctcgtccagc acgctggctc cctcggtctc cagagacggg
     5341 atggagtgca gcagatccca catgacctcg aagtggttgt ccatctcgcg gccgccgcgc
     5401 atcacatagc cgatatcgta cttgtagcca tcgcaggcac cgcctgccag tgcgttcttt
     5461 tcaaacacat ggacgtgctc gcccttcatc tggccgtcac gcaccagata gcaggcagcg
     5521 gtcagggctg ccagaccgga gccgatgata taagcggatt tatgatccac gccctccggc
     5581 tttttggggt gtgcaaaagc ttcataattg ccactggaat agtacataaa aaagcctccc
     5641 tgcttcaaaa atatcttttc acagccttca tcgtgctgtt ctctatggca acagtatacc
     5701 ccgcaaagtg aaccggaaca acaaacaaac tttgcccggt gtatagattt tttacatccg
     5761 ccctcatttg ctggaaatgc gtacaaattg tgacataaag cgcagcgcaa aatcatttaa
     5821 aacactctct caaaagtgca atgccgggca gcccgcaggc tgcccggtat tgcactaatt
     5881 taaaataatt ttccgctatt catgcccaga gcatagcggc gggcattcaa aatcgtcccc
     5941 gcgcaaaaag agagccgccg cacaaggttc tgtgcagcgg ctctccggtg gattttagtt
     6001 catctcttcc agagcttttt tcaggttctt tgcaatctgg tccgggcagc tggtgctgcg
     6061 gaagccgcac aacgtgccgt ccagacgggc aatggcgtcc tctgccttca tgccggtaag
     6121 cagctggcag atgcccttca ggttgccgtt gcagccgccg acgacctcaa tggaagcaat
     6181 ggtgtggtca tcgttcagca caaagttggt ctgcttggag caggtaccct tgttcgggaa
     6241 ggaaaattcc ttgctcatag tctttacgtc ctctctcttt tacgtttttc ggcgatggcg
     6301 cgcagctgcg ctgcggcttc gtccggtgcg gtgcaggtgc cgatggggtg ggggtgcttg
     6361 tggttgcggc catggaagtc cgtgcccgca gtagccacaa ggccgtactg tttgcacagg
     6421 gcaaggcact cggcgctgtc ctccgggctg ttgctgggat ggtacacttc aatgccgtcc
     6481 actgcgccct ctgctgccag ctcccgcagc aggggcatac ttttatacac cgtggggtgg
     6541 gcaaacacca ccgcgccgcc gcttgccttg gcggtagcca gcacctgccg caccggcaga
     6601 tactccggcg agtgcagcac gatgccccgg gggttccacc cgaacagctt gtggtaggtc
     6661 tcgccgtaga tgctgccatc ggtcagaccc agcagttcca gtgcctgcat cagcccgctt
     6721 ttgaacagca ccccgctggc ctttgtggtc tcccatgcaa ggtcggtggt aaactgcggg
     6781 tacagctgtt ccagctcctt tgcgctctgc aaagcgcagg cgttgcggcg ctccttcatg
     6841 atggcgcaat gctcgcgcag cgccgggcag tcaatgtccg ggtagtagca cagcaggtgc
     6901 acccggtgct ggcgctcgaa gtcgtagccg gtcagctcca cggcggggat cagctctacc
     6961 ccgtcctgcc cggtgtgggc ataggcgtac tgagcgctga gcagggtgtc gtggtccgaa
     7021 agggcgatgg cgtgcagccc ggtgcgggcg gcgatgggtg ccagccgctc gatgggcaca
     7081 gcaccgtccg agcaggtgga atggatatgc aggtcacagg acatagcggg ttacttcctt
     7141 agtgcttata gaaattgatc aggcagccgt cagccaggat ctggcgctcg tcggtggtga
     7201 gcggagccat gtacagctca aactccttga cggtatcgcc cagaacatag gccttgatgc
     7261 tctgcaggtc gcccttgagt gcctcccgca cattggggat gagcacatag tcccccagac
     7321 caaagggggt ggcgcctgcc agctgcaggg gcagcatgcc ccagttgatg agattagagc
     7381 ggtaacgctt ggtggcgtac tcggttacga tattggcacc ggcacccagc acacgctggc
     7441 agctggcggc ctgctcacgg gcagagccgt cgccgggctt gaccgcaaag atggtagagg
     7501 cgatctggat atcgttccag ctcagcttct cgcagccggg cacggcgttc acctttgcca
     7561 gcagggcggc gtcccctgca ccggcgcggc gggcagcttc ctcggcctgc acggccttgg
     7621 cgcgactcac atactccggg tccttgcggc tgagggtgaa ctcagccaga cccagcggat
     7681 tggaacggta agaggacgtc tcgccggagg ggatcagctc atcggtggtg gtgacggggt
     7741 cggtgatata agaagccacc ttcagcagca gattgtcgcc cagcggtgcg atctccggcc
     7801 agtccttgat gttggggcca aatttgagca gggcatcgta atcgcccttg ccaaagccct
     7861 gatagacgcg ggtgtcgtag ctggaagcat cgtactggta ctccggcacg gtgggatcgt
     7921 aatcaatgtc ggtggcgggg gtcaggatgc cgccgtttgc ggtggtggct gcaatgctgc
     7981 gggcatccat cagtgccaca ccggccagct ggccgctgcc gggcttggag ccctcgcggc
     8041 tggggaagtt gcgggtggtg tgacggatgg acagtgcacc gttggcgggc acatcgcctg
     8101 cgccgaagca ggggccgcag aaggcggtgc ggatggtagc gccgctggcc atcaactcgc
     8161 caatgacgcc ggtgcgcacc agttccatca tgatgggctg actgccgggg taaacgctca
     8221 aggcgtagtc gccgcagccg ccggtatgac ccttgaggat ggaagcagcc tcgtagatgc
     8281 tgtcgtacag accgcctgcg cagcctgcaa tgacgccctg atccacacgc agcttgccgt
     8341 tttcgatctt gctgcacaga tccagctgca catccttgcg gccgatcagc ttctgcacat
     8401 cctgctcgca ggcgtggagg atgtcctcca gatttgcgtt cagttcctcg atggtaaagg
     8461 cgttggaggg gtgcatgggc agggcgatca tgggacggat ggcagaaaga tccacctcca
     8521 ccacgccatc gtagtaggca aggtctgccg gtgccagctt tttatagtct gctgcacggc
     8581 cgtgcaccgc cagaaaacgc tgggtaactt cgtcggtctc ccagatggag gacaggcagg
     8641 tggtctcggt ggtcatggca tcaatggcgt tgcgggtatc ctgccgcagg gaggcaatgc
     8701 cggggcccac gaactccatg accttgttct tgacgtagcc gctcttgaac agcttgccca
     8761 caagggcaat ggctacatcg tgggggccgc agcccgccgg cagactgccg gtcaggtaga
     8821 tggccaccac acccgggcgg gcaacatcat aggtgcggcc cagcagctgc tttgccagct
     8881 cgccgccgcc ttcaccgata gccatggtgc ccagtgcgcc gtagcgtgtg tgggagtccg
     8941 agccaaggat cattttgccg cagccggcaa agcgctcgcg catatactgg tggatgactg
     9001 ccatgtgcgg gggcacaaag ataccgccgt actttttggc agcggacagg ccaaagcggt
     9061 ggtcgtcctc gttgatggtg ccgcccacag cgcacaggct gttgtggcag ttggtaagca
     9121 cataaggaat gggaaacttt tccagcccgg aagcacgggc ggtctggatg atgcccacaa
     9181 aggtgatgtc atggcttgcc atggcatcaa acttgatctt caggttctcg gcatcgccgc
     9241 tggtgttgtg tgcctgcata atattgtagg ccatggtacc ggtcttagcc gcggcaacgg
     9301 cagcggcatc aaagcccttt gctgccagtg ctgcgggtgc attgccatct gcgggcaccc
     9361 actctccgcg cgcatagtac gcaccgccag tgctgcattt gatcatatcc aacatctcga
     9421 ttcgcctctc tttttgtatt ttcccgcccg ccgcaattgc gggcattgcc ccggcagtgc
     9481 ggctattcat cccgaaaaca gccgtcccct tagccttcac cccttggggg ggaagccatt
     9541 aagcaaacca gcttttcaaa gacttataac ccctgccctg ttacggcaaa agccgtattt
     9601 aatttttatt atagcatgaa agggcgaaaa gaaaaagcat tttttatgaa cccttactgc
     9661 acctttgcgg cggcttcctg ctgcttttcc ttttgcagtc tgcggaacac cacaaaatag
     9721 gccgggatca ggaagaagca ggcaaagagc catgccaccg ggcttgcgat gcaggcggca
     9781 aagtagcccc acagcggcac gaaccagaag cccaccatgg cgcgggcgat catttcagcc
     9841 acaccggcaa acatggcaag gccggagtgt cccagaccct gaatggtgta gcggtagatg
     9901 ataagcactg ccagcgggat gtagaacaca ctgttccaga agatgaagtc ctgcgcattg
     9961 gccataatgg cggtctcgcc tgcgtccaaa aacaggccga tcaggggctt gtccagcacg
    10021 cgcaggatga ggaaggaggc cacgctgtac acgcagccga tgcccagtgc ggtgttcacg
    10081 ccgcggttca cgcggcccag atccttcgcg cccatattct ggctggtgta ggtggtcatg
    10141 gcggtgccga tgctctccag cggcacgctg aggaactgcg cagccttgcc gccggcggtc
    10201 tgcgcggcta cgatatcgct gcccagaccg ttcaccgcgc cctgcagcac cacgctgccg
    10261 atggcagtaa tactgcactg cagacccatg gggaggccca tggcgcaaag ctttgcgcag
    10321 tgcggagcgc tgatgcgccc ttcttcctta ttccagcgca gttccgggta gtggcgcatg
    10381 atgtaaataa ggctgccgat gcctgccaca gcctgactga acacggtggc aaaagccgcg
    10441 ccgaacacgc ccatgttgaa caggatgatg caggcaaggt ccagcccgat gttcagcacg
    10501 ctggccacca gcaggaaata cagcgggcgc ttgctgtcgc ccagtgcacg catcagggcg
    10561 ctggtcacat tataaagcag cgtgaagggg atgcctgcaa aaatggtgcg gatatagata
    10621 tccgcaaggt cgatgatatc ggccggggtg ttcgtccaca ccagcaccag atgggtcatt
    10681 gccaccgtaa cgatggtaag caccgtggca aaggcgatgg acagccacac ggtattggcg
    10741 gtgtagcggc gcatctcgtg gtggtcgtgg gcaccgaagg tccatgagat ggggat
//
